# terms

id: MONDO:0014933
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any early infantile epileptic encephalopathy in which the cause of the disease is a mutation in the UBA5 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"undetermined early-onset epileptic encephalopathy","termid":"MONDO:0018614"},{"relation_name":"is_a","term_name":"neonatal-onset developmental and epileptic encephalopathy","termid":"MONDO:0100455"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0700092"},{"rel_name":"is_a","termid":"MONDO:0004736"},{"rel_name":"is_a","termid":"MONDO:0005027"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0700092","MONDO:0005066","MONDO:0004736","MONDO:0005027"],"is_obsolete":false,"name":"developmental and epileptic encephalopathy, 44","secondary_identifiers":["DOID:0080424","GARD:16198","MEDGEN:934667","OMIM:617132","UMLS:C4310700"],"synonyms":[{"name":"DEE44","type":"exact"},{"name":"EIEE44","type":"exact"},{"name":"UBA5 early infantile epileptic encephalopathy","type":"exact"},{"name":"developmental and epileptic encephalopathy 44","type":"exact"},{"name":"early infantile epileptic encephalopathy caused by mutation in UBA5","type":"exact"},{"name":"epileptic encephalopathy, early infantile, 44","type":"exact"},{"name":"epileptic encephalopathy, early infantile, 44; EIEE44","type":"exact"},{"name":"epileptic encephalopathy, early infantile, type 44","type":"exact"}],"termid":"MONDO:0014933","xrefs":{"Monarch":{"xref_id":"0014933"}}}


id: MONDO:0004045
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Retinoblastoma during childhood that has not spread beyond the eye.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intraocular retinoblastoma","termid":"MONDO:0003077"},{"relation_name":"is_a","term_name":"childhood malignant neoplasm","termid":"MONDO:0006517"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0005328"],"is_obsolete":false,"name":"pediatric intraocular retinoblastoma","secondary_identifiers":["NCIT:C9047","DOID:6938","MEDGEN:230836","UMLS:C1321869"],"synonyms":[{"name":"childhood intraocular retinoblastoma","type":"exact"},{"name":"intraocular retinoblastoma","type":"broad"},{"name":"intraocular retinoblastoma of childhood","type":"exact"},{"name":"pediatric intraocular retinoblastoma","type":"exact"}],"termid":"MONDO:0004045","xrefs":{"Monarch":{"xref_id":"0004045"}}}


id: MONDO:1012537
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hypopigmentation and deafness, non-human animal","termid":"MONDO:1011900"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hypopigmentation and deafness, pig","secondary_identifiers":["OMIA:002287-9823"],"termid":"MONDO:1012537","xrefs":{"Monarch":{"xref_id":"1012537"}}}


id: FYPO:0003572
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 in heterochromatin at subtelomeric regions occurs to a lower extent than normal.","definition_xrefs":["PomBase:mah","PMID:18761674"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased histone H3-K9 methylation during vegetative growth","termid":"FYPO:0000872"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000002","FYPO:0005447","FYPO:0002274","FYPO:0002494","FYPO:0001985"],"is_obsolete":false,"name":"decreased histone H3-K9 methylation at subtelomeric heterochromatin during vegetative growth","synonyms":[{"name":"decreased histone H3 K9 methylation at subtelomeric heterochromatin during vegetative growth","type":"exact"},{"name":"decreased histone H3-K9 methylation at subtelomeres during vegetative growth","type":"exact"},{"name":"decreased histone H3-K9 methylation at subtelomeric heterochromatin during mitotic cell cycle","type":"related"},{"name":"decreased histone H3-K9 methylation at telomeric heterochromatin during vegetative growth","type":"related"},{"name":"decreased histone H3K9me at subtelomeric heterochromatin during vegetative growth","type":"exact"},{"name":"decreased histone lysine H3 K9 methylation at subtelomeric heterochromatin during vegetative growth","type":"exact"},{"name":"reduced histone H3-K9 methylation at subtelomeric heterochromatin during vegetative growth","type":"exact"}],"termid":"FYPO:0003572"}


id: GO:2000561
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of alpha-beta T cell proliferation","termid":"GO:0046640"},{"relation_name":"is_a","term_name":"regulation of CD4-positive, alpha-beta T cell activation","termid":"GO:2000514"},{"relation_name":"regulates","term_name":"CD4-positive, alpha-beta T cell proliferation","termid":"GO:0035739"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of CD4-positive, alpha-beta T cell proliferation","termid":"GO:2000561"}


id: MONDO:0010452
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any non-syndromic X-linked intellectual disability in which the cause of the disease is a mutation in the DLG3 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"non-syndromic X-linked intellectual disability","termid":"MONDO:0019181"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"intellectual disability, X-linked 90","secondary_identifiers":["MEDGEN:477074","DOID:0112041","OMIM:300850","UMLS:C3275443","GARD:22690"],"synonyms":[{"name":"DLG3 non-syndromic X-linked intellectual disability","type":"exact"},{"name":"MRX90","type":"related"},{"name":"intellectual developmental disorder, X-linked 90, X-linked recessive","type":"exact"},{"name":"intellectual disability, X-linked 90","type":"exact"},{"name":"intellectual disability, X-linked type 90","type":"exact"},{"name":"mental retardation, X-linked 90","type":"related"},{"name":"mental retardation, X-linked type 90","type":"exact"},{"name":"non-syndromic X-linked intellectual disability caused by mutation in DLG3","type":"exact"}],"termid":"MONDO:0010452","xrefs":{"Monarch":{"xref_id":"0010452"}}}


id: RO:0002151
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"x partially overlaps y iff there exists some z such that z is part of x and z is part of y, and it is also the case that neither x is part of y or y is part of x","direct_ancestors":[{"relation_name":"is_a","term_name":"overlaps","termid":"RO:0002131"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"partially_overlaps","termid":"RO:0002151"}


id: PBO:0082875
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Covalently linked cell wall glycoprotein; present in the inner layer of the cell wall","termid":"PBO:0082875"}


id: GO:0002555
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The regulated release of histamine by a platelet or group of platelets.","definition_xrefs":["GOC:add","PMID:9117517"],"direct_ancestors":[{"relation_name":"is_a","term_name":"histamine secretion involved in inflammatory response","termid":"GO:0002441"},{"relation_name":"is_a","term_name":"establishment of localization in cell","termid":"GO:0051649"},{"relation_name":"is_a","term_name":"exocytic process","termid":"GO:0140029"},{"relation_name":"part_of","term_name":"platelet degranulation","termid":"GO:0002576"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"part_of","termid":"GO:0016192"}],"interesting_parent_ids":["GO:0008150","GO:0051179","GO:0016192","GO:0006810","GO:0023052"],"is_obsolete":false,"name":"histamine secretion by platelet","termid":"GO:0002555"}


id: PBO:0000395
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2.7.1.7","termid":"PBO:0000395"}


id: MONDO:0017511
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Split hand, unilateral is a rare, non-syndromic limb reduction defect, clinically and genetically heterogeneous, characterized by unilateral underdevelopment or absence of the central rays of the autopod, with absence of all, or just some, of the central phalanges and at least part of the associated metacarpal bones, yielding a cleft appearance of the hand. It is frequently associated with syndactyly and aplasia/hypoplasia of remaining digits and metacarpal bones. No other dysmorphic features are observed and development is appropriate for age.","definition_xrefs":["Orphanet:295120"],"direct_ancestors":[{"relation_name":"is_a","term_name":"split hand","termid":"MONDO:0017449"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"split hand, unilateral","secondary_identifiers":["icd11.foundation:1675694993"],"termid":"MONDO:0017511","xrefs":{"Monarch":{"xref_id":"0017511"}}}


id: GO:1900547
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in negative regulation of phenotypic switching.","definition_xrefs":["GOC:di","GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter (obsolete GO:1900547)","synonyms":[{"name":"negative regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter","type":"related"}],"termid":"GO:1900547"}


id: GO:0031631
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of vesicle fusion","termid":"GO:0031339"},{"relation_name":"is_a","term_name":"regulation of synaptic vesicle fusion to presynaptic active zone membrane","termid":"GO:0031630"},{"relation_name":"is_a","term_name":"negative regulation of synaptic vesicle membrane organization","termid":"GO:1901633"},{"relation_name":"is_a","term_name":"negative regulation of synaptic vesicle exocytosis","termid":"GO:2000301"},{"relation_name":"negatively_regulates","term_name":"synaptic vesicle fusion to presynaptic active zone membrane","termid":"GO:0031629"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"negatively_regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0016192"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"negatively_regulates","termid":"GO:0016192"},{"rel_name":"regulates","termid":"GO:0061024"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0061024"}],"interesting_parent_ids":["GO:0061024","GO:0006810","GO:0016192","GO:0023052","GO:0008150"],"is_obsolete":false,"name":"negative regulation of synaptic vesicle fusion to presynaptic active zone membrane","synonyms":[{"name":"down regulation of synaptic vesicle fusion to presynaptic active zone membrane","type":"exact"},{"name":"down regulation of synaptic vesicle fusion to presynaptic membrane","type":"broad"},{"name":"down-regulation of synaptic vesicle fusion to presynaptic active zone membrane","type":"exact"},{"name":"down-regulation of synaptic vesicle fusion to presynaptic membrane","type":"broad"},{"name":"downregulation of synaptic vesicle fusion to presynaptic active zone membrane","type":"exact"},{"name":"downregulation of synaptic vesicle fusion to presynaptic membrane","type":"broad"},{"name":"inhibition of synaptic vesicle fusion to presynaptic membrane","type":"broad"},{"name":"negative regulation of synaptic vesicle fusion to pre-synaptic active zone membrane","type":"exact"},{"name":"negative regulation of synaptic vesicle fusion to pre-synaptic membrane","type":"broad"},{"name":"negative regulation of synaptic vesicle fusion to presynaptic membrane","type":"broad"}],"termid":"GO:0031631"}


id: PBO:0004752
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcription factor Ste11","termid":"PBO:0004752"}


id: GO:0030285
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. The component of the synaptic vesicle membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.","definition_xrefs":["GOC:dos","GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete integral component of synaptic vesicle membrane (obsolete GO:0030285)","synonyms":[{"name":"integral to synaptic vesicle membrane","type":"narrow"}],"termid":"GO:0030285"}


id: FYPO:0008212
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 in silent mating-type cassettes does not occur.","definition_xrefs":["PomBase:vw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished histone H3-K9 methylation during vegetative growth","termid":"FYPO:0002566"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001985","FYPO:0001320","FYPO:0005447","FYPO:0002274","FYPO:0002494"],"is_obsolete":false,"name":"abolished histone H3-K9 methylation at silent mating-type cassette during vegetative growth","termid":"FYPO:0008212"}


id: GO:0140770
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-lysyl-[protein] + tetradecanoyl-CoA = CoA + H+ + N(6)-tetradecanoyl-L-lysyl-[protein].","definition_xrefs":["RHEA:59752","PMID:1402651"],"direct_ancestors":[{"relation_name":"is_a","term_name":"peptidyl-lysine N6-myristoyltransferase activity","termid":"GO:0018030"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0016740","GO:0003674","GO:0140096","GO:0003824","GO:0016746"],"is_obsolete":false,"name":"CoA-dependent peptidyl-lysine N6-myristoyltransferase activity","termid":"GO:0140770"}


id: PBO:0072574
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribonucleotide reductase M2 polypeptide pseudogene 2","termid":"PBO:0072574"}


id: MONDO:0000097
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete thyroid dyshormonogenesis (obsolete MONDO:0000097)","termid":"MONDO:0000097","xrefs":{"Monarch":{"xref_id":"0000097"}}}


id: FYPO:0005281
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"OBSOLETE. A cell morphology phenotype in which a vegetatively growing cell is inviable, is elongated, and contains DNA broken into small fragments when the cell is exposed to ionizing radiation.","definition_xrefs":["PomBase:mah","PMID:1594599"],"gene_count":0,"genotype_count":0,"name":"obsolete inviable elongated vegetative cell with fragmented DNA during cellular response to ionizing radiation (obsolete FYPO:0005281)","synonyms":[{"name":"elongated inviable cell with fragmented DNA during cellular response to ionizing radiation","type":"exact"},{"name":"inviable elongated cell with fragmented DNA during cellular response to ionizing radiation during vegetative growth","type":"exact"},{"name":"inviable elongated vegetative cell with fragmented DNA during cellular response to gamma radiation","type":"narrow"},{"name":"inviable elongated vegetative cell with fragmented DNA during cellular response to ionizing radiation","type":"exact"},{"name":"inviable elongated vegetative cell with fragmented DNA during cellular response to ionizing radiation during mitotic cell cycle","type":"related"},{"name":"inviable elongated vegetative cell with fragmented nucleus during cellular response to ionizing radiation","type":"related"},{"name":"lethal; elongated vegetative cell with fragmented DNA during cellular response to ionizing radiation","type":"exact"}],"termid":"FYPO:0005281"}


id: PBO:0085999
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein of unknown function; similar to Listeria monocytogenes major sigma factor (rpoD gene product); the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies","termid":"PBO:0085999"}


id: FYPO:0006143
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dephosphorylation of protein tyrosine residues begins later than normal. All protein tyrosine dephosphorylation may be affected, or tyrosine residues in one or more specific proteins, or at specific protein sites, or even specific sites within specific proteins.","definition_xrefs":["PomBase:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete delayed onset of protein tyrosine dephosphorylation during vegetative growth (obsolete FYPO:0006143)","synonyms":[{"name":"delayed onset of peptidyl-tyrosine dephosphorylation during vegetative growth","type":"exact"},{"name":"delayed onset of protein tyrosine dephosphorylation during mitotic cell cycle","type":"related"},{"name":"delayed protein tyrosine dephosphorylation during vegetative growth","type":"exact"}],"termid":"FYPO:0006143"}


id: GO:0051019
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a mitogen-activated protein kinase.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein kinase binding","termid":"GO:0019901"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0005488","GO:0003674","GO:0005515"],"is_obsolete":false,"name":"mitogen-activated protein kinase binding","synonyms":[{"name":"MAP kinase binding","type":"exact"},{"name":"MAP-kinase anchoring activity","type":"related"},{"name":"MAPK binding","type":"exact"}],"termid":"GO:0051019"}


id: PBO:0091924
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dpb3 was previously considered to be SPAC17G8.03c but this new gene product appears to be the true ortholog of DPB3/POLE4 see TreeFam:TF103009 and PMID:29109278","termid":"PBO:0091924"}


id: PBO:0001848
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATPase with bromodomain protein (predicted)","termid":"PBO:0001848"}


id: PBO:0064310
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proteolipid protein 2","termid":"PBO:0064310"}


id: PR:O74804
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- est1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O74804"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"telomere elongation protein est1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC2D10.13","synonyms":[{"name":"Spom972h-est1","type":"exact"},{"name":"ever shorter telomeres protein 1 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O74804"}


id: SO:0000928
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"An edit to insert a AA dinucleotide.","definition_xrefs":["SO:ke"],"gene_count":0,"genotype_count":0,"name":"OBSOLETE SO:0000928 insert_AA (obsolete SO:0000928)","synonyms":[{"name":"insert AA","type":"exact"}],"termid":"SO:0000928"}


id: GO:0006139
data:
  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id: MONDO:0005763
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  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Infections with viruses of the family flaviviridae.","definition_xrefs":["MESH:D018178"],"direct_ancestors":[{"relation_name":"is_a","term_name":"primary viral infectious disease","termid":"MONDO:0100329"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Flaviviridae infectious disease","secondary_identifiers":["EFO:0007274","SCTID:111865007"],"synonyms":[{"name":"Flaviviridae caused disease or disorder","type":"exact"},{"name":"Flaviviridae disease or disorder","type":"exact"}],"termid":"MONDO:0005763","xrefs":{"Monarch":{"xref_id":"0005763"}}}


id: GO:1990804
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  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any protein phosphorylation process that is required for double-strand break repair via nonhomologous end joining.","definition_xrefs":["PMID:22563681","GOC:rb","GO_REF:0000060","GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete protein phosphorylation involved in double-strand break repair via nonhomologous end joining (obsolete GO:1990804)","synonyms":[{"name":"protein amino acid phosphorylation involved in NHEJ","type":"exact"},{"name":"protein amino acid phosphorylation involved in double-strand break repair via nonhomologous end joining","type":"exact"},{"name":"protein phosphorylation involved in NHEJ","type":"exact"}],"termid":"GO:1990804"}


id: MONDO:0018347
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete severe intellectual disability-progressive postnatal microcephaly- midline stereotypic hand movements syndrome (obsolete MONDO:0018347)","termid":"MONDO:0018347","xrefs":{"Monarch":{"xref_id":"0018347"}}}


id: PBO:0054077
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1427","termid":"PBO:0054077"}


id: PBO:0057289
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 509-1","termid":"PBO:0057289"}


id: GO:1904316
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  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine stimulus.","definition_xrefs":["GOC:TermGenie","PMID:9321918","GO_REF:0000071"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to lipid","termid":"GO:0033993"},{"relation_name":"is_a","term_name":"response to ether","termid":"GO:0045472"},{"relation_name":"is_a","term_name":"response to organophosphorus","termid":"GO:0046683"},{"relation_name":"is_a","term_name":"response to nitrogen compound","termid":"GO:1901698"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine","synonyms":[{"name":"response to PAF","type":"exact"},{"name":"response to platelet-activating factor","type":"exact"}],"termid":"GO:1904316"}


id: PBO:0045450
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dihydropyrimidinase like 3","termid":"PBO:0045450"}


id: MONDO:0022875
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cortada Koussef Matsumoto syndrome","termid":"MONDO:0022875","xrefs":{"Monarch":{"xref_id":"0022875"}}}


id: GO:0018448
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: hydroxymethylmethylsilanediol + O2 + 2 H+ + 2 e- = formylmethylsilanediol + 2 H2O.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete hydroxymethylmethylsilanediol oxidase activity (obsolete GO:0018448)","termid":"GO:0018448"}


id: GO:0052427
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process in which an organism effects a change in symbiont peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"gene_count":0,"genotype_count":0,"name":"obsolete modulation by host of symbiont peptidase activity (obsolete GO:0052427)","synonyms":[{"name":"modulation by host of symbiont protease activity","type":"narrow"}],"termid":"GO:0052427"}


id: GO:0090324
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.","definition_xrefs":["GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of oxidative phosphorylation","termid":"GO:0002082"},{"relation_name":"is_a","term_name":"negative regulation of cellular respiration","termid":"GO:1901856"},{"relation_name":"negatively_regulates","term_name":"oxidative phosphorylation","termid":"GO:0006119"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0006091"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006091"}],"interesting_parent_ids":["GO:0008150","GO:0006091"],"is_obsolete":false,"name":"negative regulation of oxidative phosphorylation","termid":"GO:0090324"}


id: PBO:0048276
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"polypeptide N-acetylgalactosaminyltransferase 12","termid":"PBO:0048276"}


id: MONDO:0019914
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Maternal uniparental disomy of chromosome 9 is an uniparental disomy of maternal origin that most likely does not have any phenotypic expression except from cases of homozygosity for a recessive disease mutation for which only mother is a carrier.","definition_xrefs":["Orphanet:96183"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chromosome 9 disorder","termid":"MONDO:0700016"},{"relation_name":"is_a","term_name":"uniparental disomy","termid":"MONDO:0700086"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"maternal uniparental disomy of chromosome 9","secondary_identifiers":["MEDGEN:1634619","SCTID:766240006","UMLS:C4707721","icd11.foundation:102102686","GARD:19335"],"synonyms":[{"name":"UPD(9)mat","type":"exact"},{"name":"maternal uniparental disomy of chromosome type 9","type":"exact"}],"termid":"MONDO:0019914","xrefs":{"Monarch":{"xref_id":"0019914"}}}


id: GO:0055105
data:
  {"annotated_genes":["SJAG_01515","SJAG_04699","SJAG_02485"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[114229],"is_not":false,"summary":null,"term":"GO:0055105"},{"annotations":[98200,115163],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990948"}]},"cv_name":"molecular_function","definition":"Binds to and stops, prevents or reduces the activity of a ubiquitin-protein transferase.","definition_xrefs":["GOC:BHF","GOC:rl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"enzyme inhibitor activity","termid":"GO:0004857"},{"relation_name":"is_a","term_name":"ubiquitin-protein transferase regulator activity","termid":"GO:0055106"}],"gene_count":3,"genes_by_uniquename":{"SJAG_01515":null,"SJAG_02485":null,"SJAG_04699":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0098772"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0030234"},{"rel_name":"is_a","termid":"GO:0004857"},{"rel_name":"is_a","termid":"GO:0140678"}],"interesting_parent_ids":["GO:0030234","GO:0098772","GO:0004857","GO:0003674","GO:0140678"],"is_obsolete":false,"name":"ubiquitin-protein transferase inhibitor activity","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0055105","terms_by_termid":{"GO:0055105":null,"GO:1990948":null}}


id: PATO:0002421
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"Having or resembling the characteristic of a cicatrix - a scar resulting from formation and contraction of fibrous tissue.","definition_xrefs":["mw:http://www.merriam-webster.com/dictionary/cicatricial"],"direct_ancestors":[{"relation_name":"is_a","term_name":"shape","termid":"PATO:0000052"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cicatricial","termid":"PATO:0002421"}


id: PBO:0005646
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"purine nucleoside transmembrane transporter (predicted)","termid":"PBO:0005646"}


id: GO:0005646
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete importin (obsolete GO:0005646)","synonyms":[{"name":"importin","type":"exact"},{"name":"karyopherin","type":"exact"}],"termid":"GO:0005646"}


id: MONDO:0019224
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. An inherited metabolic disease that is has its basis in the disruption of gamma-aminobutyric acid metabolic process.","definition_xrefs":["MONDO:patterns/inborn_metabolic"],"gene_count":0,"genotype_count":0,"name":"obsolete inborn disorder of gamma-aminobutyric acid metabolism (obsolete MONDO:0019224)","synonyms":[{"name":"disorder of GABA metabolism","type":"exact"},{"name":"disorder of gamma-aminobutyric acid metabolism","type":"related"},{"name":"inborn error of gamma-aminobutyric acid metabolic process","type":"exact"},{"name":"inborn gamma-aminobutyric acid metabolic process disorder","type":"exact"},{"name":"rare inborn error of gamma-aminobutyric acid metabolic process","type":"exact"}],"termid":"MONDO:0019224","xrefs":{"Monarch":{"xref_id":"0019224"}}}


id: PBO:0075602
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SPOC domain containing 1","termid":"PBO:0075602"}


id: MONDO:0032598
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"developmental and epileptic encephalopathy","termid":"MONDO:0100062"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0700092"},{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0700092","MONDO:0005027"],"is_obsolete":false,"name":"developmental and epileptic encephalopathy, 68","secondary_identifiers":["DOID:0112204","MEDGEN:1648479","GARD:16310","OMIM:618201","UMLS:C4748688"],"synonyms":[{"name":"DEE68","type":"exact"},{"name":"EIEE68","type":"exact"},{"name":"EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 68","type":"exact"},{"name":"developmental and epileptic encephalopathy 68","type":"exact"},{"name":"epileptic encephalopathy, early infantile, 68","type":"exact"}],"termid":"MONDO:0032598","xrefs":{"Monarch":{"xref_id":"0032598"}}}


id: GO:0035209
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the pupa over time, from its formation to the mature structure. The pupa is a dormant life stage interposed between the larval and the adult stages in insects that undergo a complete metamorphosis.","definition_xrefs":["GOC:mtg_sensu","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"instar larval or pupal development","termid":"GO:0002165"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"pupal development","termid":"GO:0035209"}


id: FYPO:0008119
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype characterized by normal cell morphology (i.e. size, shape, and structure indistinguishable from wild type) when the cell is subject to phophate starvation.","definition_xrefs":["PMID:36794724"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal cell morphology","termid":"FYPO:0000672"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0000002"],"is_obsolete":false,"name":"normal morphology during phosphate starvation","termid":"FYPO:0008119"}


id: PBO:0071034
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L21 pseudogene 36","termid":"PBO:0071034"}


id: GO:0038034
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals initiated by the absence of a ligand or the withdrawal of a ligand from a receptor.","definition_xrefs":["GOC:pr","GOC:al","GOC:ppm","PMID:15044679"],"direct_ancestors":[{"relation_name":"is_a","term_name":"signal transduction","termid":"GO:0007165"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"signal transduction in absence of ligand","synonyms":[{"name":"addiction receptor signaling pathway","type":"broad"},{"name":"basal signaling","type":"narrow"},{"name":"dependence receptor signaling pathway","type":"broad"},{"name":"negative signal transduction","type":"related"},{"name":"non-classical signal transduction","type":"broad"},{"name":"signal transduction in absence of agonist","type":"exact"}],"termid":"GO:0038034"}


id: GO:1904671
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any negative regulation of cell differentiation that is involved in stem cell population maintenance.","definition_xrefs":["GO_REF:0000060","GOC:BHF","GOC:BHF_miRNA","GOC:rph","PMID:19409607","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cell differentiation","termid":"GO:0045596"},{"relation_name":"part_of","term_name":"stem cell population maintenance","termid":"GO:0019827"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of cell differentiation involved in stem cell population maintenance","synonyms":[{"name":"down regulation of cell differentiation involved in maintenance of pluripotency","type":"related"},{"name":"down regulation of cell differentiation involved in stem cell population maintenance","type":"exact"},{"name":"down-regulation of cell differentiation involved in maintenance of pluripotency","type":"related"},{"name":"down-regulation of cell differentiation involved in stem cell population maintenance","type":"exact"},{"name":"downregulation of cell differentiation involved in maintenance of pluripotency","type":"related"},{"name":"downregulation of cell differentiation involved in stem cell population maintenance","type":"exact"},{"name":"inhibition of cell differentiation involved in maintenance of pluripotency","type":"related"},{"name":"inhibition of cell differentiation involved in stem cell population maintenance","type":"narrow"},{"name":"negative regulation of cell differentiation involved in maintenance of pluripotency","type":"related"}],"termid":"GO:1904671"}


id: GO:0140296
data:
  {"annotated_genes":["SJAG_03900","SJAG_00692","SJAG_01523","SJAG_02174","SJAG_00650","SJAG_03095","SJAG_00202","SJAG_02458","SJAG_00159","SJAG_03007","SJAG_03120","SJAG_00095"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[81658],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0001179"},{"annotations":[78613,72394,73803,77493,58333,72244,67561,79043],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0017025"},{"annotations":[80988],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0001096"},{"annotations":[77932],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0001097"},{"annotations":[73565],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0001156"}]},"cv_name":"molecular_function","definition":"Binding to a general transcription initiation factor, a protein that contributes to transcription start site selection and transcription initiation.","definition_xrefs":["GOC:txnOH-2018"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transcription factor binding","termid":"GO:0008134"}],"gene_count":12,"genes_by_uniquename":{"SJAG_00095":null,"SJAG_00159":null,"SJAG_00202":null,"SJAG_00650":null,"SJAG_00692":null,"SJAG_01523":null,"SJAG_02174":null,"SJAG_02458":null,"SJAG_03007":null,"SJAG_03095":null,"SJAG_03120":null,"SJAG_03900":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005515"}],"interesting_parent_ids":["GO:0003674","GO:0005488","GO:0005515"],"is_obsolete":false,"name":"general transcription initiation factor binding","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null},"termid":"GO:0140296","terms_by_termid":{"GO:0001096":null,"GO:0001097":null,"GO:0001156":null,"GO:0001179":null,"GO:0017025":null}}


id: MONDO:0054832
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"posterior polymorphous corneal dystrophy","termid":"MONDO:0020364"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"corneal dystrophy, posterior polymorphous, 4","secondary_identifiers":["OMIM:618031","DOID:0080669","MEDGEN:1648359","UMLS:C4747961","GARD:18215"],"synonyms":[{"name":"PPCD4","type":"related"},{"name":"corneal dystrophy, POSTERIOR polymorphous, 4","type":"related"}],"termid":"MONDO:0054832","xrefs":{"Monarch":{"xref_id":"0054832"}}}


id: GO:0051628
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the directed movement of epinephrine into a cell.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of transport","termid":"GO:0051050"},{"relation_name":"is_a","term_name":"regulation of epinephrine uptake","termid":"GO:0051626"},{"relation_name":"positively_regulates","term_name":"epinephrine uptake","termid":"GO:0051625"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0008150"],"is_obsolete":false,"name":"positive regulation of epinephrine uptake","synonyms":[{"name":"activation of epinephrine uptake","type":"narrow"},{"name":"positive regulation of adrenaline uptake","type":"exact"},{"name":"positive regulation of epinephrine import","type":"exact"},{"name":"stimulation of epinephrine uptake","type":"narrow"},{"name":"up regulation of epinephrine uptake","type":"exact"},{"name":"up-regulation of epinephrine uptake","type":"exact"},{"name":"upregulation of epinephrine uptake","type":"exact"}],"termid":"GO:0051628"}


id: GO:0019501
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of arsonoacetate, a synthetic, organic compound containing a single arsenic atom.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"arsonoacetate metabolic process","termid":"GO:0018872"},{"relation_name":"is_a","term_name":"xenobiotic catabolic process","termid":"GO:0042178"},{"relation_name":"is_a","term_name":"carboxylic acid catabolic process","termid":"GO:0046395"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0044281"],"is_obsolete":false,"name":"arsonoacetate catabolic process","secondary_identifiers":["MetaCyc:P482-PWY"],"synonyms":[{"name":"arsonoacetate breakdown","type":"exact"},{"name":"arsonoacetate catabolism","type":"exact"},{"name":"arsonoacetate degradation","type":"exact"}],"termid":"GO:0019501"}


id: PBO:0001900
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA polymerase zeta catalytic subunit Rev3 (predicted)","termid":"PBO:0001900"}


id: PBO:0083814
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Essential SNARE protein localized to the ER; involved in retrograde traffic from the Golgi to the ER and Sey1p-independent homotypic ER fusion; required for efficient nuclear fusion during mating; forms a complex with the SNAREs Sec22p, Sec20p and Ufe1p","termid":"PBO:0083814"}


id: GO:1901789
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of benzoyl-CoA.","definition_xrefs":["GOC:TermGenie","GOC:yaf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acyl-CoA biosynthetic process","termid":"GO:0071616"},{"relation_name":"is_a","term_name":"benzoyl-CoA metabolic process","termid":"GO:1901787"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006790"}],"interesting_parent_ids":["GO:0055086","GO:0006790","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"benzoyl-CoA biosynthetic process","synonyms":[{"name":"benzoyl-CoA anabolism","type":"exact"},{"name":"benzoyl-CoA biosynthesis","type":"exact"},{"name":"benzoyl-CoA formation","type":"exact"},{"name":"benzoyl-CoA synthesis","type":"exact"}],"termid":"GO:1901789"}


id: MONDO:0007256
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation.","definition_xrefs":["NCIT:C3099"],"direct_ancestors":[{"relation_name":"is_a","term_name":"adenocarcinoma","termid":"MONDO:0004970"},{"relation_name":"is_a","term_name":"carcinoma of liver and intrahepatic biliary tract","termid":"MONDO:0018531"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002515"},{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0002515","MONDO:0004992"],"is_obsolete":false,"name":"hepatocellular carcinoma","secondary_identifiers":["GARD:16773","MEDGEN:389187","DOID:686","MedDRA:10049010","Orphanet:88673","UMLS:C2239176","icd11.foundation:1294035808","MESH:D006528","NORD:1907","DOID:684","OMIM:114550","ICDO:8170/3","NANDO:2200047","ONCOTREE:HCC","EFO:0000182"],"synonyms":[{"name":"HCC","type":"exact"},{"name":"adult hepatoma","type":"narrow"},{"name":"adult primary hepatocellular carcinoma","type":"narrow"},{"name":"cancer, hepatocellular","type":"exact"},{"name":"carcinoma of liver","type":"exact"},{"name":"carcinoma of liver cells","type":"exact"},{"name":"carcinoma of the liver cells","type":"exact"},{"name":"carcinoma, hepatocellular, malignant","type":"exact"},{"name":"hepatoblastoma","type":"related"},{"name":"hepatoblastoma caused by somatic mutation","type":"related"},{"name":"hepatoblastoma, somatic","type":"exact"},{"name":"hepatocellular adenocarcinoma","type":"exact"},{"name":"hepatocellular cancer","type":"exact"},{"name":"hepatocellular cancer, somatic","type":"exact"},{"name":"hepatocellular carcinoma","type":"exact"},{"name":"hepatocellular carcinoma, childhood type, somatic","type":"exact"},{"name":"hepatocellular carcinoma, somatic","type":"exact"},{"name":"hepatoma","type":"exact"},{"name":"liver and intrahepatic bile duct carcinoma","type":"related"},{"name":"liver cancer","type":"related"},{"name":"liver carcinoma","type":"exact"},{"name":"liver cell cancer (hepatocellular carcinoma)","type":"exact"},{"name":"liver cell carcinoma","type":"exact"},{"name":"primary carcinoma of liver cells","type":"exact"},{"name":"primary carcinoma of the liver cells","type":"exact"}],"termid":"MONDO:0007256","xrefs":{"Monarch":{"xref_id":"0007256"}}}


id: PBO:0027997
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-inviable_multinucleate_aseptate_vegetative_cell","termid":"PBO:0027997"}


id: FYPO:0005010
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"OBSOLETE. A cellular process phenotype in which the phosphorylation of serine residues three positions C-terminal to arginine residues (i.e. in Arg-X-X-Ser, or RxxS, sequences) occurs to a greater extent than normal when the cell is subject to nitrogen starvation.","definition_xrefs":["PMID:22976295","PomBase:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete increased protein serine phosphorylation at RxxS site during nitrogen starvation (obsolete FYPO:0005010)","synonyms":[{"name":"increased protein serine phosphorylation at Arg-X-X-Ser site during nitrogen starvation","type":"exact"},{"name":"increased protein serine phosphorylation at PAS site during nitrogen starvation","type":"exact"},{"name":"increased protein serine phosphorylation at RxxS site during cellular response to nitrogen starvation","type":"exact"},{"name":"increased protein serine phosphorylation at RxxS site during nitrogen depletion","type":"exact"},{"name":"increased protein serine phosphorylation at RxxS site during nitrogen deprivation","type":"exact"},{"name":"increased protein serine phosphorylation at arginine-X-X-serine site during nitrogen starvation","type":"exact"},{"name":"increased protein serine phosphorylation at phospho-Akt site during nitrogen starvation","type":"exact"}],"termid":"FYPO:0005010"}


id: PBO:0058478
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 5585","termid":"PBO:0058478"}


id: GO:0090482
data:
  {"annotated_genes":["SJAG_02780","SJAG_02779","SJAG_02962","SJAG_03503","SJAG_04673","SJAG_05175","SJAG_03652","SJAG_00835"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[73545,81005],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015225"},{"annotations":[75647],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008517"},{"annotations":[100197],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034216"},{"annotations":[74226],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015233"},{"annotations":[103167],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0090422"},{"annotations":[89617,89616],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015234"}]},"cv_name":"molecular_function","definition":"Enables the transfer of a vitamin from one side of a membrane to the other.","definition_xrefs":["GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transmembrane transporter activity","termid":"GO:0022857"}],"gene_count":8,"genes_by_uniquename":{"SJAG_00835":null,"SJAG_02779":null,"SJAG_02780":null,"SJAG_02962":null,"SJAG_03503":null,"SJAG_03652":null,"SJAG_04673":null,"SJAG_05175":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0003674","GO:0005215","GO:0022857"],"is_obsolete":false,"name":"vitamin transmembrane transporter activity","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["GO:0051183"],"synonyms":[{"name":"vitamin or cofactor transporter activity","type":"broad"},{"name":"vitamin transporter activity","type":"related"}],"termid":"GO:0090482","terms_by_termid":{"GO:0008517":null,"GO:0015225":null,"GO:0015233":null,"GO:0015234":null,"GO:0034216":null,"GO:0090422":null}}


id: MONDO:0010261
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"eye disorder","termid":"MONDO:0005328"},{"relation_name":"excluded_subClassOf","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"},{"relation_name":"excluded_subClassOf","term_name":"microphthalmia, Lenz type","termid":"MONDO:0018924"},{"relation_name":"excluded_subClassOf","term_name":"X-linked syndromic intellectual disability","termid":"MONDO:0020119"},{"relation_name":"is_a","term_name":"syndromic microphthalmia","termid":"MONDO:0016073"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"microphthalmia, syndromic 2","secondary_identifiers":["Orphanet:2712","DOID:0111809","GARD:4628","MEDGEN:337547","SCTID:699300009","UMLS:C1846265","ICD9:759.89","OMIM:300166"],"synonyms":[{"name":"ANOP2 (formerly)","type":"related"},{"name":"MAA2 (formerly)","type":"related"},{"name":"MCOPS2","type":"related"},{"name":"OFCD syndrome","type":"exact"},{"name":"cataract-microphthalmia-radiculomegaly-cardiac septal defect syndrome","type":"exact"},{"name":"microphthalmia cataracts radiculomegaly and septal heart defects","type":"related"},{"name":"microphthalmia syndromic 2","type":"exact"},{"name":"microphthalmia, cataracts, radiculomegaly, and septal heart defects","type":"related"},{"name":"microphthalmia, syndromic 2","type":"exact"},{"name":"microphthalmia, syndromic 2, X-linked dominant","type":"exact"},{"name":"microphthalmia, syndromic type 2","type":"exact"},{"name":"oculofaciocardiodental syndrome","type":"exact"},{"name":"syndromic microphthalmia type 2","type":"related"}],"termid":"MONDO:0010261","xrefs":{"Monarch":{"xref_id":"0010261"}}}


id: GO:0007207
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A phospholipase C-activating G protein-coupled receptor signaling pathway initiated by acetylcholine binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.","definition_xrefs":["GOC:mah","GOC:tb","GOC:dph","GOC:signaling"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phospholipase C-activating G protein-coupled receptor signaling pathway","termid":"GO:0007200"},{"relation_name":"is_a","term_name":"G protein-coupled acetylcholine receptor signaling pathway","termid":"GO:0007213"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway","synonyms":[{"name":"activation of phospholipase C activity by G-protein coupled acetylcholine receptor signaling pathway","type":"related"},{"name":"activation of phospholipase C activity by muscarinic acetylcholine receptor signaling pathway","type":"related"},{"name":"activation of phospholipase C activity by muscarinic acetylcholine receptor signalling pathway","type":"exact"},{"name":"muscarinic acetylcholine receptor, phospholipase C activating pathway","type":"related"},{"name":"muscarinic receptor signaling pathway via activation of PLC","type":"exact"},{"name":"phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway","type":"exact"}],"termid":"GO:0007207"}


id: GO:0046904
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to calcium oxalate, CaC2O4, a salt of oxalic acid. In animals, it may be excreted in urine or retained in the form of urinary calculi.","definition_xrefs":["ISBN:0721662544"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxylic acid binding","termid":"GO:0031406"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005488"],"is_obsolete":false,"name":"calcium oxalate binding","termid":"GO:0046904"}


id: GO:0090217
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that decreases the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.","definition_xrefs":["GOC:dph","GOC:tb"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity (obsolete GO:0090217)","termid":"GO:0090217"}


id: MONDO:0019399
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Isaac's syndrome is an immune-mediated peripheral motor neuron disorder characterized by continuous muscle fiber activity at rest resulting in muscle stiffness, cramps, myokymia, and pseudomyotonia.","definition_xrefs":["Orphanet:84142"],"direct_ancestors":[{"relation_name":"is_a","term_name":"muscular channelopathy","termid":"MONDO:0019119"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Isaac syndrome","secondary_identifiers":["UMLS:C0242287","SCTID:305719002","icd11.foundation:646523932","MEDGEN:116151","NANDO:1200510","GARD:6793"],"synonyms":[{"name":"Isaac's-Merten's syndrome","type":"related"},{"name":"Isaac-Mertens syndrome","type":"related"},{"name":"Isaacs' syndrome","type":"exact"},{"name":"Quantal squander syndrome","type":"exact"},{"name":"acquired neuromyotonia","type":"exact"},{"name":"continuous muscle fiber activity syndrome","type":"exact"},{"name":"continuous muscle fibre activity syndrome","type":"exact"},{"name":"neuromyotonia","type":"exact"},{"name":"peripheral nerve hyperexcitability","type":"exact"}],"termid":"MONDO:0019399","xrefs":{"Monarch":{"xref_id":"0019399"}}}


id: PBO:0041728
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"calcium/calmodulin dependent protein kinase II gamma","termid":"PBO:0041728"}


id: PBO:0035694
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-causally_upstream_of,_negative_effect","termid":"PBO:0035694"}


id: GO:0004196
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the degradation of gelatin; little activity on hemoglobin. Specificity on B chain of insulin more restricted than pepsin A; does not cleave Phe1-Val2, Gln4-His5 or Gly23-Phe24.","definition_xrefs":["EC:3.4.23.25"],"gene_count":0,"genotype_count":0,"name":"obsolete saccharopepsin activity (obsolete GO:0004196)","synonyms":[{"name":"PRA","type":"related"},{"name":"Saccharomyces aspartic proteinase activity","type":"narrow"},{"name":"aspartic proteinase yscA","type":"related"},{"name":"proteinase A","type":"related"},{"name":"proteinase yscA","type":"related"},{"name":"saccharomyces aspartic proteinase activity","type":"related"},{"name":"saccharomyces cerevisiae aspartic proteinase A","type":"related"},{"name":"saccharopepsin activity","type":"exact"},{"name":"yeast endopeptidase A activity","type":"narrow"},{"name":"yeast proteinase A","type":"related"}],"termid":"GO:0004196"}


id: MONDO:0100604
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A hereditary disease that encompasses the spectrum of clinical phenotypes resulting from loss of function of the TOR1AIP1 gene, including TOR1AIP1-related myopathy and TOR1AIP1-related multisystem disorder. Variability in the specific clinical features resulting from variants disrupting the function the TOR1AIP1 gene is thought to depend on the differential effects of variants on TOR1AIP1 transcript isoforms, for which there is evidence for tissue-specific expression and function.","definition_xrefs":["PMID:37108075"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TOR1AIP1-related nuclear envelopathy","termid":"MONDO:0100604","xrefs":{"Monarch":{"xref_id":"0100604"}}}


id: PBO:0062722
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 51 subfamily T member 1","termid":"PBO:0062722"}


id: PBO:0091313
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial ABC1 kinase family protein, human ADCK5 ortholog, unknown role","termid":"PBO:0091313"}


id: MONDO:0021476
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign neoplasm that involves the tongue.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sensory organ benign neoplasm","termid":"MONDO:0000633"},{"relation_name":"is_a","term_name":"tongue neoplasm","termid":"MONDO:0021240"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"benign neoplasm of tongue","secondary_identifiers":["icd11.foundation:487744161","ICD9:210.1","ICD10CM:D10.1","UMLS:C0153933","SCTID:92443005","NCIT:C3592","MEDGEN:57573"],"synonyms":[{"name":"benign neoplasm of the tongue","type":"exact"},{"name":"benign tongue neoplasm","type":"exact"},{"name":"benign tongue tumor","type":"exact"},{"name":"benign tongue tumour","type":"exact"},{"name":"benign tumor of the tongue","type":"exact"},{"name":"benign tumor of tongue","type":"exact"},{"name":"benign tumour of the tongue","type":"exact"},{"name":"benign tumour of tongue","type":"exact"},{"name":"tongue benign neoplasm","type":"exact"},{"name":"tongue neoplasm, benign","type":"exact"}],"termid":"MONDO:0021476","xrefs":{"Monarch":{"xref_id":"0021476"}}}


id: PBO:0041725
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"calcium/calmodulin dependent protein kinase II alpha","termid":"PBO:0041725"}


id: PBO:0090844
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nicotinamide riboside kinase Nrk1","termid":"PBO:0090844"}


id: PBO:0084846
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial ribosomal protein of the large subunit; homolog of prokaryotic L29 ribosomal protein; located at the ribosomal tunnel exit","termid":"PBO:0084846"}


id: MONDO:0009347
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"phagocytic cell dysfunction","termid":"MONDO:0024627"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"familial lipochrome histiocytosis","secondary_identifiers":["UMLS:C0334125","OMIM:235900","MESH:C562738","MEDGEN:90743","SCTID:234577004"],"synonyms":[{"name":"histiocytosis, familial lipochrome","type":"related"}],"termid":"MONDO:0009347","xrefs":{"Monarch":{"xref_id":"0009347"}}}


id: PBO:0002844
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP-dependent DNA helicase Snf21","termid":"PBO:0002844"}


id: PBO:0058839
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 8069","termid":"PBO:0058839"}


id: MOD:00984
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"modification from DeltaMass","definition_xrefs":["DeltaMass:0"],"direct_ancestors":[{"relation_name":"is_a","term_name":"3',5'-dichloro-L-tyrosine","termid":"MOD:01045"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"(35)Cl labeled 3',5'-dichlorotyrosine","termid":"MOD:00984"}


id: PBO:0088563
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DUF2433 metallo phosphatase superfamily conserved fungal protein","termid":"PBO:0088563"}


id: PBO:0059917
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-ND2 pseudogene 3","termid":"PBO:0059917"}


id: GO:0051677
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glucan biosynthetic process","termid":"GO:0009250"},{"relation_name":"is_a","term_name":"pullulan metabolic process","termid":"GO:0051676"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0005975","GO:0008150"],"is_obsolete":false,"name":"pullulan biosynthetic process","termid":"GO:0051677"}


id: PBO:0011125
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3-oxoacyl-[acyl-carrier-protein]reductase (predicted)","termid":"PBO:0011125"}


id: PBO:0065478
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PSMD14 divergent transcript","termid":"PBO:0065478"}


id: MONDO:0030998
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant nonsyndromic hearing loss","termid":"MONDO:0019587"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0019497"}],"interesting_parent_ids":["MONDO:0000426","MONDO:0019497"],"is_obsolete":false,"name":"hearing loss, autosomal dominant 80","secondary_identifiers":["GARD:18158","MEDGEN:1779667","OMIM:619274","UMLS:C5543289"],"synonyms":[{"name":"DFNA80","type":"narrow"},{"name":"deafness, autosomal dominant 80","type":"narrow"}],"termid":"MONDO:0030998","xrefs":{"Monarch":{"xref_id":"0030998"}}}


id: PBO:0061631
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nudix hydrolase 14","termid":"PBO:0061631"}


id: PR:O94649
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- atg2 gene.","definition_xrefs":["UniProtKB:O94649","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"autophagy-related protein 2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC31E1.01c","synonyms":[{"name":"Spom972h-atg2","type":"exact"},{"name":"meiotically up-regulated gene 36 protein (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O94649"}


id: MONDO:0002281
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Anemia that is characterized by increased red blood cell volume.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anemia","termid":"MONDO:0002280"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002280"},{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0002280"],"is_obsolete":false,"name":"macrocytic anemia","secondary_identifiers":["MESH:D000748","UMLS:C0002886","SCTID:83414005","MEDGEN:1920","NCIT:C34381","DOID:2361","HP:0001972"],"synonyms":[{"name":"D22S676","type":"exact"},{"name":"D22S750","type":"exact"},{"name":"anaemia macrocytic","type":"exact"},{"name":"anemia macrocytic","type":"exact"},{"name":"macrocytic Anaemia","type":"exact"},{"name":"macrocytic Anemia","type":"exact"},{"name":"macrocytic anaemia (disease)","type":"exact"},{"name":"macrocytic anaemia of unspecified cause","type":"exact"},{"name":"macrocytic anemia","type":"exact"},{"name":"macrocytic anemia (disease)","type":"exact"},{"name":"macrocytic anemia of unspecified cause","type":"exact"}],"termid":"MONDO:0002281","xrefs":{"Monarch":{"xref_id":"0002281"}}}


id: PBO:0061675
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nucleoporin 62 C-terminal like","termid":"PBO:0061675"}


id: PBO:0055630
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 3069","termid":"PBO:0055630"}


id: MONDO:0020142
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete metabolic disease with dementia (obsolete MONDO:0020142)","secondary_identifiers":["Orphanet:98543"],"termid":"MONDO:0020142","xrefs":{"Monarch":{"xref_id":"0020142"}}}


id: PBO:0025537
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by N. crassa TNC","termid":"PBO:0025537"}


id: PBO:0089010
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial fusion protein Ugo1","termid":"PBO:0089010"}


id: PBO:0083462
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the verified gene KTR3","termid":"PBO:0083462"}


id: PBO:0044256
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"C-X3-C motif chemokine ligand 1","termid":"PBO:0044256"}


id: FYPO:0007444
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which macroautophagy is normal (i.e. indistinguishable from wild type) during a cellular response to endoplasmic reticulum stress.","definition_xrefs":["PMID:32735772","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal macroautophagy","termid":"FYPO:0000385"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000257"],"is_obsolete":false,"name":"normal macroautophagy during cellular response to endoplasmic reticulum stress","synonyms":[{"name":"normal macroautophagy during cellular response to ER stress","type":"exact"},{"name":"normal macroautophagy during cellular response to endoplasmic reticulum stress during mitotic cell cycle","type":"related"},{"name":"normal macroautophagy during cellular response to endoplasmic reticulum stress during vegetative growth","type":"exact"}],"termid":"FYPO:0007444"}


id: MONDO:0007553
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"epidermolysis bullosa with deficiency of galactosylhydroxylysyl glucosyltransferase","secondary_identifiers":["MESH:C565049","UMLS:C1851570","MEDGEN:342036","OMIM:131880"],"synonyms":[{"name":"epidermolysis bullosa with deficiency of galactosylhydroxylysyl glucosyltransferase","type":"exact"}],"termid":"MONDO:0007553","xrefs":{"Monarch":{"xref_id":"0007553"}}}


id: GO:0033756
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: Oplophorus luciferin + O2 = oxidized Oplophorus luciferin + CO2 + hnu.","definition_xrefs":["EC:1.13.12.13"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)","termid":"GO:0016703"},{"relation_name":"is_a","term_name":"luciferin monooxygenase activity","termid":"GO:0045289"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"Oplophorus-luciferin 2-monooxygenase activity","secondary_identifiers":["MetaCyc:RXN-3361","RHEA:20417"],"synonyms":[{"name":"Oplophorus luciferase activity","type":"related"},{"name":"Oplophorus-luciferin:oxygen 2-oxidoreductase (decarboxylating) activity","type":"related"}],"termid":"GO:0033756"}


id: PR:O74942
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A peptidylprolyl isomerase domain and WD repeat-containing protein 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO04259","PANTHER:PTHR11071:SF40","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peptidyl-prolyl cis-trans isomerase 9 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC553.04","secondary_identifiers":["UniProtKB:O74942"],"synonyms":[{"name":"PPIase cyp9 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-PPWD1","type":"exact"},{"name":"cyclophilin 9 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"rotamase cyp9 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O74942"}


id: PBO:0080526
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WAS protein family homolog 8, pseudogene","termid":"PBO:0080526"}


id: PBO:0053922
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1219","termid":"PBO:0053922"}


id: PBO:0067984
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 286","termid":"PBO:0067984"}


id: GO:0006596
data:
  {"annotated_genes":["SJAG_04481","SJAG_04546","SJAG_03632","SJAG_00043"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[110755],"is_not":false,"rel_names":["negatively_regulates","regulates"],"summary":null,"term":"GO:0170066"},{"annotations":[77519],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033387"},{"annotations":[79628,76761],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008295"},{"annotations":[79627,102284],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006597"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polyamine metabolic process","termid":"GO:0006595"},{"relation_name":"is_a","term_name":"biogenic amine biosynthetic process","termid":"GO:0042401"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00043":null,"SJAG_03632":null,"SJAG_04481":null,"SJAG_04546":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"polyamine biosynthetic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-351200"],"synonyms":[{"name":"polyamine anabolism","type":"exact"},{"name":"polyamine biosynthesis","type":"exact"},{"name":"polyamine formation","type":"exact"},{"name":"polyamine synthesis","type":"exact"}],"termid":"GO:0006596","terms_by_termid":{"GO:0006597":null,"GO:0008295":null,"GO:0033387":null,"GO:0170066":null}}


id: PBO:0072299
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S24 pseudogene 17","termid":"PBO:0072299"}


id: GO:0005124
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to scavenger receptors, a family of proteins that are expressed on myeloid cells and are involved in the uptake of effete cellular components and foreign particles.","definition_xrefs":["GOC:ceb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"signaling receptor binding","termid":"GO:0005102"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005515"}],"interesting_parent_ids":["GO:0005515","GO:0005488","GO:0003674"],"is_obsolete":false,"name":"scavenger receptor binding","synonyms":[{"name":"scavenger receptor ligand","type":"narrow"}],"termid":"GO:0005124"}


id: GO:0071650
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of chemokine production","termid":"GO:0032682"},{"relation_name":"is_a","term_name":"regulation of chemokine (C-C motif) ligand 5 production","termid":"GO:0071649"},{"relation_name":"negatively_regulates","term_name":"chemokine (C-C motif) ligand 5 production","termid":"GO:0071609"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"negatively_regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"negative regulation of chemokine (C-C motif) ligand 5 production","synonyms":[{"name":"negative regulation of CCL5 production","type":"exact"},{"name":"negative regulation of RANTES production","type":"exact"},{"name":"negative regulation of Regulated upon Activation, Normal T-cell Expressed, and Secreted production","type":"exact"}],"termid":"GO:0071650"}


id: SO:1000094
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","gene_count":0,"genotype_count":0,"name":"OBSOLETE SO:1000094 sequence_variant_causing_conservative_amino_acid_substitution (obsolete SO:1000094)","synonyms":[{"name":"mutation causing conservative amino acid substitution","type":"related"},{"name":"sequence variant causing conservative amino acid substitution","type":"exact"}],"termid":"SO:1000094"}


id: PBO:0030098
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_cellular_glutathione_level_during_vegetative_growth","termid":"PBO:0030098"}


id: MONDO:0002573
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete pleomorphic rhabdomyosarcoma (obsolete MONDO:0002573)","termid":"MONDO:0002573","xrefs":{"Monarch":{"xref_id":"0002573"}}}


id: PBO:0038479
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP binding cassette subfamily B member 4","termid":"PBO:0038479"}


id: GO:0033887
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 4-sulfate + H2O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H+ + sulfate.","definition_xrefs":["EC:3.1.6.9","RHEA:11444"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sulfuric ester hydrolase activity","termid":"GO:0008484"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016788"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016788","GO:0016787"],"is_obsolete":false,"name":"chondro-4-sulfatase activity","secondary_identifiers":["MetaCyc:CHONDRO-4-SULFATASE-RXN","KEGG_REACTION:R03517"],"synonyms":[{"name":"4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase activity","type":"related"}],"termid":"GO:0033887"}


id: MOD:01621
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that crosslinks two or more amino acid residues by forming an adduct with a compound containing a flavin group.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"crosslinked residues","termid":"MOD:00033"},{"relation_name":"is_a","term_name":"flavin modified residue","termid":"MOD:00697"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"flavin crosslinked residues","termid":"MOD:01621"}


id: PBO:0054050
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1392","termid":"PBO:0054050"}


id: GO:0033264
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete bontoxilysin activity (obsolete GO:0033264)","synonyms":[{"name":"BoNT","type":"related"},{"name":"bontoxilysin activity","type":"exact"},{"name":"botulinum neurotoxin activity","type":"exact"}],"termid":"GO:0033264"}


id: PBO:0089896
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"trans-aconitate 3-methyltransferase","termid":"PBO:0089896"}


id: MONDO:0000267
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete cryptogenic organizing pneumonia (obsolete MONDO:0000267)","termid":"MONDO:0000267","xrefs":{"Monarch":{"xref_id":"0000267"}}}


id: GO:0002307
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta regulatory T cell.","definition_xrefs":["ISBN:0781735149","GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"CD8-positive, alpha-beta T cell differentiation","termid":"GO:0043374"},{"relation_name":"is_a","term_name":"regulatory T cell differentiation","termid":"GO:0045066"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"CD8-positive, alpha-beta regulatory T cell differentiation","synonyms":[{"name":"CD8-positive, alpha-beta regulatory T cell development","type":"related"},{"name":"CD8-positive, alpha-beta regulatory T lymphocyte differentiation","type":"exact"},{"name":"CD8-positive, alpha-beta regulatory T-cell differentiation","type":"exact"},{"name":"CD8-positive, alpha-beta regulatory T-lymphocyte differentiation","type":"exact"}],"termid":"GO:0002307"}


id: GO:2001032
data:
  {"annotated_genes":["SJAG_00823","SJAG_03048"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[101892],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:2001033"},{"annotations":[106962],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:2001034"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of double-strand break repair via nonhomologous end joining.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of double-strand break repair","termid":"GO:2000779"},{"relation_name":"regulates","term_name":"double-strand break repair via nonhomologous end joining","termid":"GO:0006303"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00823":null,"SJAG_03048":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006281"},{"rel_name":"regulates","termid":"GO:0006259"}],"interesting_parent_ids":["GO:0006259","GO:0006281","GO:0008150"],"is_obsolete":false,"name":"regulation of double-strand break repair via nonhomologous end joining","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"regulation of NHEJ","type":"exact"}],"termid":"GO:2001032","terms_by_termid":{"GO:2001033":null,"GO:2001034":null}}


id: MONDO:0030750
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"junctional epidermolysis bullosa","termid":"MONDO:0017612"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"epidermolysis bullosa, junctional 4, intermediate","secondary_identifiers":["MEDGEN:382015","OMIM:619787","UMLS:C2608084"],"synonyms":[{"name":"JEB4","type":"exact"},{"name":"epidermolysis bullosa, generalised atrophic benign","type":"exact"},{"name":"epidermolysis bullosa, generalized atrophic benign","type":"exact"},{"name":"epidermolysis bullosa, junctional 4, intermediate","type":"exact"},{"name":"epidermolysis bullosa, junctional 4, non-herlitz IIA","type":"exact"},{"name":"epidermolysis bullosa, junctional, localisata variant","type":"exact"}],"termid":"MONDO:0030750","xrefs":{"Monarch":{"xref_id":"0030750"}}}


id: PBO:0054310
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1702","termid":"PBO:0054310"}


id: MONDO:1010533
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Gingival hypertrophy that occurs in dog.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gingival hypertrophy, non-human animal","termid":"MONDO:1010038"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"gingival hypertrophy, dog","secondary_identifiers":["OMIA:000409-9615"],"termid":"MONDO:1010533","xrefs":{"Monarch":{"xref_id":"1010533"}}}


id: PBO:0050999
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"intraflagellar transport associated protein","termid":"PBO:0050999"}


id: MONDO:0006260
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A type of renal carcinoma affecting mostly young African-Americans. It is located in the medulla of the kidney, and follows an aggressive clinical course. Most reported cases have shown metastatic disease at the time of diagnosis.","definition_xrefs":["NCIT:C7572"],"direct_ancestors":[{"relation_name":"is_a","term_name":"renal cell carcinoma","termid":"MONDO:0005086"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0005240"],"is_obsolete":false,"name":"kidney medullary carcinoma","secondary_identifiers":["EFO:1000314","GARD:13175","UMLS:C4049328","MedDRA:10064886","NORD:1999","MEDGEN:888108","MONDO:0017888","ONCOTREE:MRC","Orphanet:319319","DOID:0070475"],"synonyms":[{"name":"Renal Medullary Carcinoma","type":"exact"},{"name":"carcinoma of renal medulla","type":"exact"},{"name":"kidney medullary carcinoma","type":"exact"},{"name":"renal medulla carcinoma","type":"exact"},{"name":"renal medullary carcinoma","type":"exact"}],"termid":"MONDO:0006260","xrefs":{"Monarch":{"xref_id":"0006260"}}}


id: GO:0051914
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a chemical substance increases synaptic plasticity, the ability of synapses to change as circumstances require.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of synaptic plasticity","termid":"GO:0031915"},{"relation_name":"is_a","term_name":"regulation of synaptic plasticity by chemical substance","termid":"GO:0051913"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"positive regulation of synaptic plasticity by chemical substance","synonyms":[{"name":"activation of synaptic plasticity by chemical substance","type":"narrow"},{"name":"positive regulation of synaptic plasticity by drug","type":"narrow"},{"name":"stimulation of synaptic plasticity by chemical substance","type":"narrow"},{"name":"up regulation of synaptic plasticity by chemical substance","type":"exact"},{"name":"up-regulation of synaptic plasticity by chemical substance","type":"exact"},{"name":"upregulation of synaptic plasticity by chemical substance","type":"exact"}],"termid":"GO:0051914"}


id: MONDO:0018494
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Microcephaly-short stature-intellectual disability-facial dysmorphism syndrome is a rare genetic malformation syndrome with short stature characterized by postnatal microcephaly, failure to thrive and short stature, global developmental delay and intellectual disability, hypotonia, dysmorphic features (short nose, depressed nasal bridge, low set ears, short neck, clinodactyly and cutaneous syndactyly of T2-3 at birth and broad forehead, midface retrusion, epicanthal folds, laterally sparse eyebrows, short nose, long philtrum, widely spaced teeth, micrognathia and coarsening of facial features later in life). Other associated features include postnatal transient generalized edema, myopia, strabismus, hypothyroidism.","definition_xrefs":["Orphanet:423306"],"direct_ancestors":[{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microcephaly-short stature-intellectual disability-facial dysmorphism syndrome","secondary_identifiers":["GARD:21751","MEDGEN:1659920","UMLS:C4749647"],"termid":"MONDO:0018494","xrefs":{"Monarch":{"xref_id":"0018494"}}}


id: PBO:0083085
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA 5' AMP hydrolase involved in DNA repair; member of the histidine triad (HIT) superfamily of nucleotide-binding proteins; homolog of Aprataxin, a Hint related protein that is mutated in individuals with ataxia with oculomotor apraxia; relative distribution to nuclear foci decreases upon DNA replication stress","termid":"PBO:0083085"}


id: GO:0031906
data:
  {"annotated_genes":["SJAG_02432"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[97140],"is_not":false,"summary":null,"term":"GO:0031906"}]},"cv_name":"cellular_component","definition":"The volume enclosed by the membrane of a late endosome.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"endosome lumen","termid":"GO:0031904"},{"relation_name":"part_of","term_name":"late endosome","termid":"GO:0005770"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02432":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0031410"},{"rel_name":"part_of","termid":"GO:0005768"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0005575","GO:0005768","GO:0005737","GO:0031410"],"is_obsolete":false,"name":"late endosome lumen","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0031906","terms_by_termid":{"GO:0031906":null}}


id: GO:0006007
data:
  {"annotated_genes":["SJAG_02009","SJAG_06621","SJAG_01310","SJAG_03660","SJAG_02796","SJAG_04495","SJAG_02135","SJAG_03903","SJAG_02107","SJAG_06622","SJAG_04192","SJAG_00605","SJAG_03373","SJAG_00027","SJAG_04334","SJAG_03828","SJAG_00461","SJAG_02369","SJAG_00839","SJAG_02945"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[108966,79617,102911,103169,105001,108965,74194,115952,108961,105370,108967,105000,97771,108964,97500,104999,105371,108962,94013,108963],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061621"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glucose metabolic process","termid":"GO:0006006"},{"relation_name":"is_a","term_name":"hexose catabolic process","termid":"GO:0019320"}],"gene_count":20,"genes_by_uniquename":{"SJAG_00027":null,"SJAG_00461":null,"SJAG_00605":null,"SJAG_00839":null,"SJAG_01310":null,"SJAG_02009":null,"SJAG_02107":null,"SJAG_02135":null,"SJAG_02369":null,"SJAG_02796":null,"SJAG_02945":null,"SJAG_03373":null,"SJAG_03660":null,"SJAG_03828":null,"SJAG_03903":null,"SJAG_04192":null,"SJAG_04334":null,"SJAG_04495":null,"SJAG_06621":null,"SJAG_06622":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0005975","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"glucose catabolic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"glucose breakdown","type":"exact"},{"name":"glucose catabolism","type":"exact"},{"name":"glucose degradation","type":"exact"}],"termid":"GO:0006007","terms_by_termid":{"GO:0061621":null}}


id: MOD:00677
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces a hydrogen atom with an hydroxyl group.","definition_xrefs":["DeltaMass:0"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbon oxygenated residue","termid":"MOD:00679"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hydroxylated residue","synonyms":[{"name":"HyRes","type":"exact"},{"name":"Hydroxylation (of delta C of Lysine, beta C of Tryptophan, C3 or C4 of Proline, beta C of Aspartate)","type":"exact"}],"termid":"MOD:00677"}


id: GO:0010574
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of production of vascular endothelial growth factor.","definition_xrefs":["GOC:rl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cytokine production","termid":"GO:0001817"},{"relation_name":"regulates","term_name":"vascular endothelial growth factor production","termid":"GO:0010573"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"regulation of vascular endothelial growth factor production","termid":"GO:0010574"}


id: PBO:0071249
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L23a pseudogene 90","termid":"PBO:0071249"}


id: FYPO:0004847
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype that affects DNA-dependent transcription.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gene expression phenotype","termid":"FYPO:0000142"},{"relation_name":"is_a","term_name":"RNA metabolism phenotype","termid":"FYPO:0000294"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000294"}],"interesting_parent_ids":["FYPO:0000294","FYPO:0000002"],"is_obsolete":false,"name":"transcription phenotype","synonyms":[{"name":"fission yeast transcription phenotype","type":"exact"}],"termid":"FYPO:0004847"}


id: PBO:0072446
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S29 pseudogene 10","termid":"PBO:0072446"}


id: PBO:0043588
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"COL18A1 antisense RNA 2","termid":"PBO:0043588"}


id: MONDO:1012442
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"malignant melanoma, non-human animal","termid":"MONDO:1011821"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"malignant melanoma, dog","secondary_identifiers":["OMIA:001724-9615"],"termid":"MONDO:1012442","xrefs":{"Monarch":{"xref_id":"1012442"}}}


id: PBO:0050592
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HscB mitochondrial iron-sulfur cluster cochaperone","termid":"PBO:0050592"}


id: FYPO:0004232
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which methylated histone binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished protein-protein interaction","termid":"FYPO:0000705"},{"relation_name":"is_a","term_name":"abnormal methylated histone binding","termid":"FYPO:0004231"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000702"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000707","FYPO:0001985","FYPO:0000702","FYPO:0000652"],"is_obsolete":false,"name":"abolished methylated histone binding","synonyms":[{"name":"methylated histone binding abolished","type":"exact"}],"termid":"FYPO:0004232"}


id: PBO:0058788
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 7157","termid":"PBO:0058788"}


id: GO:2000995
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of mannan catabolic process.","definition_xrefs":["GOC:mengo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cellodextrin metabolic process","termid":"GO:2000925"},{"relation_name":"is_a","term_name":"negative regulation of cell wall polysaccharide catabolic process","termid":"GO:2000967"},{"relation_name":"is_a","term_name":"regulation of mannan catabolic process","termid":"GO:2000994"},{"relation_name":"negatively_regulates","term_name":"mannan catabolic process","termid":"GO:0046355"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0005975"},{"rel_name":"regulates","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0005975","GO:0008150"],"is_obsolete":false,"name":"negative regulation of mannan catabolic process","synonyms":[{"name":"negative regulation of mannan breakdown","type":"exact"},{"name":"negative regulation of mannan catabolism","type":"exact"},{"name":"negative regulation of mannan degradation","type":"exact"}],"termid":"GO:2000995"}


id: PBO:0030423
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-excess_endoplasmic_reticulum_membrane_present","termid":"PBO:0030423"}


id: MONDO:0018796
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete isolated constitutional thrombocytopenia (obsolete MONDO:0018796)","secondary_identifiers":["Orphanet:477797"],"synonyms":[{"name":"Cconstitutional thrombocytopenia without extra-hematopoietic manifestation","type":"exact"},{"name":"non-syndromic constitutional thrombocytopenia","type":"exact"}],"termid":"MONDO:0018796","xrefs":{"Monarch":{"xref_id":"0018796"}}}


id: PBO:0056835
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MGAT3 antisense RNA 1","termid":"PBO:0056835"}


id: PBO:0078029
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T cell receptor alpha joining 19 (non-functional)","termid":"PBO:0078029"}


id: PBO:0071171
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L23a pseudogene 11","termid":"PBO:0071171"}


id: PBO:0002770
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GTPase Ypt4","termid":"PBO:0002770"}


id: MONDO:0010618
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hypoparathyroidism in which the inheritance is recessive and linked to the q26-q27 region of the X chromosome. The parathyroid glands are usually incompletely developed (parathyroid dysgenesis) or absent (parathyroid agenesis).","definition_xrefs":["NCIT:C131079"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hypoparathyroidism, familial isolated 1","termid":"MONDO:0007796"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066"],"is_obsolete":false,"name":"familial isolated hypoparathyroidism due to agenesis of parathyroid gland","secondary_identifiers":["icd11.foundation:1282942432","DOID:0111388","OMIM:307700","UMLS:C0342344","GARD:16589","MESH:C563238","Orphanet:2239","MEDGEN:87437"],"synonyms":[{"name":"HYPX","type":"related"},{"name":"X-linked hypoparathyroidism","type":"exact"},{"name":"hypoparathyroidism, X-linked","type":"related"},{"name":"parathyroid glands, agenesis of","type":"related"}],"termid":"MONDO:0010618","xrefs":{"Monarch":{"xref_id":"0010618"}}}


id: PBO:0034609
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-inviable_after_spore_germination_with_elongated_germ_tube_and_fragmented_nucleus","termid":"PBO:0034609"}


id: PBO:0116272
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of SAGA and NuA4 histone acetyltransferase complexes; subunit of the TTT Hsp90 cochaperone complex that is involved in chromatin remodeling and telomeric chromatin regulation; interacts with acidic activators (e.g., Gal4p) which leads to transcription activation; similar to human TRRAP, which is a cofactor for c-Myc mediated oncogenic transformation","termid":"PBO:0116272"}


id: PBO:0054481
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1881","termid":"PBO:0054481"}


id: FYPO:0007431
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which mutations occur at a higher or lower rate than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vegetative cell phenotype","termid":"FYPO:0001320"},{"relation_name":"is_a","term_name":"abnormal phenotype","termid":"FYPO:0001985"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"altered mutation rate","synonyms":[{"name":"abnormal mutation rate","type":"exact"},{"name":"altered mutation rate during mitotic cell cycle","type":"related"},{"name":"altered mutation rate during vegetative growth","type":"exact"}],"termid":"FYPO:0007431"}


id: PBO:0072548
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"regulatory associated protein of MTOR complex 1","termid":"PBO:0072548"}


id: FYPO:0005127
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA transcribed from late meiotic genes measured in a cell is higher than normal (i.e. higher than observed in wild-type cells during vegetative growth). Late meiotic genes are normally transcribed during spore maturation.","definition_xrefs":["PomBase:mah","PMID:17927811","PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased level of meiotic gene mRNA during vegetative growth","termid":"FYPO:0002173"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0006551"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0006551","FYPO:0001320","FYPO:0005447","FYPO:0000002"],"is_obsolete":false,"name":"increased level of late meiotic gene mRNA during vegetative growth","synonyms":[{"name":"increased level of late meiosis gene mRNA during vegetative growth","type":"exact"},{"name":"increased level of late meiotic gene RNA during vegetative growth","type":"exact"},{"name":"increased level of late meiotic gene mRNA during vegetative growth during mitotic cell cycle","type":"related"},{"name":"increased level of late meiotic gene transcripts during vegetative growth","type":"exact"}],"termid":"FYPO:0005127"}


id: MOD:01550
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces a hydrogen atom of a protein N-terminal with the Applied Biosystems iTRAQ8plex-116 reporter+balance group.","definition_xrefs":["Unimod:730#N-term"],"direct_ancestors":[{"relation_name":"is_a","term_name":"iTRAQ8plex-116 reporter+balance reagent acylated residue","termid":"MOD:01549"},{"relation_name":"is_a","term_name":"iTRAQ8plex reporter+balance reagent acylated N-terminal","termid":"MOD:01712"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"iTRAQ8plex-116 reporter+balance reagent acylated N-terminal","synonyms":[{"name":"(4-methylpiperazin-1-yl)acetyl","type":"exact"},{"name":"Applied Biosystems iTRAQ(TM) multiplexed quantitation chemistry","type":"related"},{"name":"Representative mass and accurate mass for 113, 114, 116 & 117","type":"related"},{"name":"iTRAQ8plex","type":"related"},{"name":"iTRAQ8plex:13C(7)15N(1)","type":"related"}],"termid":"MOD:01550"}


id: GO:0042185
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of m-xylene, 1,3-dimethylbenzene, a colorless, liquid aromatic hydrocarbon.","definition_xrefs":["GOC:jl","GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"m-xylene metabolic process","termid":"GO:0018949"},{"relation_name":"is_a","term_name":"xylene catabolic process","termid":"GO:0042184"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"m-xylene catabolic process","secondary_identifiers":["MetaCyc:PWY-142"],"synonyms":[{"name":"m-xylene breakdown","type":"exact"},{"name":"m-xylene catabolism","type":"exact"},{"name":"m-xylene degradation","type":"exact"},{"name":"meta-xylene catabolic process","type":"exact"},{"name":"meta-xylene catabolism","type":"exact"}],"termid":"GO:0042185"}


id: GO:1900015
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of cytokine production involved in inflammatory response.","definition_xrefs":["GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cytokine production","termid":"GO:0001817"},{"relation_name":"regulates","term_name":"cytokine production involved in inflammatory response","termid":"GO:0002534"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"regulation of cytokine production involved in inflammatory response","synonyms":[{"name":"regulation of cytokine production involved in acute inflammatory response","type":"narrow"}],"termid":"GO:1900015"}


id: GO:0051100
data:
  {"annotated_genes":["SJAG_04887","SJAG_03088"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[104696,94787],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1904530"}]},"cv_name":"biological_process","definition":"Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of molecular function","termid":"GO:0044092"},{"relation_name":"is_a","term_name":"regulation of binding","termid":"GO:0051098"}],"gene_count":2,"genes_by_uniquename":{"SJAG_03088":null,"SJAG_04887":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of binding","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"down regulation of binding","type":"exact"},{"name":"down-regulation of binding","type":"exact"},{"name":"downregulation of binding","type":"exact"},{"name":"inhibition of binding","type":"narrow"}],"termid":"GO:0051100","terms_by_termid":{"GO:1904530":null}}


id: PBO:0047779
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FOXD1 antisense RNA 1","termid":"PBO:0047779"}


id: GO:1901960
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving isobutanol.","definition_xrefs":["GOC:TermGenie","PMID:22224870","GOC:mengo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"primary alcohol metabolic process","termid":"GO:0034308"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0044281"],"is_obsolete":false,"name":"isobutanol metabolic process","synonyms":[{"name":"isobutanol metabolism","type":"exact"}],"termid":"GO:1901960"}


id: PBO:0048131
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fucosyltransferase 11","termid":"PBO:0048131"}


id: PBO:0041542
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 17 open reading frame 100","termid":"PBO:0041542"}


id: PBO:0042890
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CFAP418 antisense RNA 1","termid":"PBO:0042890"}


id: GO:0051180
data:
  {"annotated_genes":["SJAG_04673","SJAG_02152","SJAG_03808","SJAG_02962","SJAG_02779","SJAG_03503","SJAG_02780","SJAG_00835","SJAG_05175","SJAG_03652"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[73547,81007],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905135"},{"annotations":[62453],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015884"},{"annotations":[103166],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990545"},{"annotations":[74227],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0098717"},{"annotations":[117077,118379,89603,89602],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903090"},{"annotations":[89605,117078,89604,118380],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903091"},{"annotations":[89606,89607,118381,117079],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903092"},{"annotations":[100196],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140125"},{"annotations":[89608,89609],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0071934"}]},"cv_name":"biological_process","definition":"The directed movement of vitamins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transport","termid":"GO:0006810"}],"gene_count":10,"genes_by_uniquename":{"SJAG_00835":null,"SJAG_02152":null,"SJAG_02779":null,"SJAG_02780":null,"SJAG_02962":null,"SJAG_03503":null,"SJAG_03652":null,"SJAG_03808":null,"SJAG_04673":null,"SJAG_05175":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0006810","GO:0051179"],"is_obsolete":false,"name":"vitamin transport","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null,"GO_REF:0000108":null},"synonyms":[{"name":"vitamin or cofactor transport","type":"broad"}],"termid":"GO:0051180","terms_by_termid":{"GO:0015884":null,"GO:0071934":null,"GO:0098717":null,"GO:0140125":null,"GO:1903090":null,"GO:1903091":null,"GO:1903092":null,"GO:1905135":null,"GO:1990545":null}}


id: PR:Q9P7Q7
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mak1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9P7Q7"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peroxide stress-activated histidine kinase mak1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1834.08","synonyms":[{"name":"Spom972h-mak1","type":"exact"},{"name":"his-Asp phosphorelay kinase phk3 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"mcs4-associated kinase 1 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9P7Q7"}


id: GO:0001578
data:
  {"annotated_genes":["SJAG_01546","SJAG_03073","SJAG_03264","SJAG_04566","SJAG_04841","SJAG_01613","SJAG_02624"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[96276,96784,98734,100963,112357,112367,117766],"is_not":false,"summary":null,"term":"GO:0001578"}]},"cv_name":"biological_process","definition":"A process that results in a parallel arrangement of microtubules.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"microtubule cytoskeleton organization","termid":"GO:0000226"}],"gene_count":7,"genes_by_uniquename":{"SJAG_01546":null,"SJAG_01613":null,"SJAG_02624":null,"SJAG_03073":null,"SJAG_03264":null,"SJAG_04566":null,"SJAG_04841":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0007010"},{"rel_name":"is_a","termid":"GO:0000226"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0000226","GO:0007010"],"is_obsolete":false,"name":"microtubule bundle formation","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"microtubule bundling","type":"exact"}],"termid":"GO:0001578","terms_by_termid":{"GO:0001578":null}}


id: PBO:0088700
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin activating enzyme E1 Uba1","termid":"PBO:0088700"}


id: PBO:0085647
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein involved in meiotic recombination; required for normal levels of crossing over, colocalizes with Zip2p to discrete foci on meiotic chromosomes, has homology to bacterial MutS protein","termid":"PBO:0085647"}


id: GO:0048867
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a cell becomes capable of differentiating autonomously into a stem cell regardless of its environment; upon determination, the cell fate cannot be reversed.","definition_xrefs":["CL:0000034","GOC:isa_complete"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell fate determination","termid":"GO:0001709"},{"relation_name":"part_of","term_name":"stem cell fate commitment","termid":"GO:0048865"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"stem cell fate determination","termid":"GO:0048867"}


id: FYPO:0001344
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the initiation of nuclear DNA replication is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal DNA replication initiation","termid":"FYPO:0000176"},{"relation_name":"is_a","term_name":"abnormal mitotic DNA replication","termid":"FYPO:0001343"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000293"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0005447","FYPO:0000002","FYPO:0001320","FYPO:0000631","FYPO:0000293"],"is_obsolete":false,"name":"abnormal mitotic DNA replication initiation","synonyms":[{"name":"abnormal DNA replication initiation during mitotic cell cycle","type":"exact"},{"name":"abnormal DNA replication initiation during vegetative growth","type":"exact"}],"termid":"FYPO:0001344"}


id: GO:0047330
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: beta-D-glucose + long chain polyphosphate = glucose-6-phosphate + long chain polyphosphate.","definition_xrefs":["EC:2.7.1.63","MetaCyc:2.7.1.63-RXN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"kinase activity","termid":"GO:0016301"},{"relation_name":"is_a","term_name":"phosphotransferase activity, alcohol group as acceptor","termid":"GO:0016773"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016301"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0003824","GO:0016301","GO:0016740","GO:0003674"],"is_obsolete":false,"name":"polyphosphate-glucose phosphotransferase activity","secondary_identifiers":["RHEA:22036"],"synonyms":[{"name":"polyphosphate glucokinase activity","type":"related"},{"name":"polyphosphate-D-(+)-glucose-6-phosphotransferase activity","type":"related"},{"name":"polyphosphate-glucose 6-phosphotransferase activity","type":"related"},{"name":"polyphosphate:D-glucose 6-phosphotransferase activity","type":"related"}],"termid":"GO:0047330"}


id: PBO:0045817
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"eukaryotic translation elongation factor 1 alpha 1 pseudogene 7","termid":"PBO:0045817"}


id: MONDO:0005659
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A chronic inflammation in which the nasal mucosa gradually changes from a functional to a non-functional lining without mucociliary clearance. It is often accompanied by degradation of the bony turbinates, and the foul-smelling mucus which forms a greenish crust (ozena).","definition_xrefs":["MESH:D012222"],"direct_ancestors":[{"relation_name":"is_a","term_name":"rhinitis","termid":"MONDO:0003014"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"atrophic rhinitis","secondary_identifiers":["UMLS:C0035459","EFO:0007159","SCTID:69646003","DOID:4731","MEDGEN:48450"],"synonyms":[{"name":"Ozaena","type":"exact"},{"name":"dry rhinitis","type":"exact"},{"name":"ozena","type":"exact"},{"name":"rhinitis sicca","type":"related"},{"name":"rhinitis, atrophic","type":"exact"}],"termid":"MONDO:0005659","xrefs":{"Monarch":{"xref_id":"0005659"}}}


id: MONDO:0030891
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"intellectual disability, autosomal dominant","termid":"MONDO:0100172"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426"],"is_obsolete":false,"name":"intellectual developmental disorder, autosomal dominant 66","secondary_identifiers":["MEDGEN:1812470","OMIM:619910","UMLS:C5677000"],"synonyms":[{"name":"MRD66","type":"exact"},{"name":"intellectual developmental disorder, autosomal dominant 66","type":"exact"},{"name":"mental retardation, autosomal dominant 66","type":"exact"}],"termid":"MONDO:0030891","xrefs":{"Monarch":{"xref_id":"0030891"}}}


id: PBO:0054961
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2375","termid":"PBO:0054961"}


id: PBO:0059563
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"metallothionein 1G","termid":"PBO:0059563"}


id: MONDO:0005650
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Virus diseases caused by the arenaviridae.","definition_xrefs":["MESH:D001117"],"direct_ancestors":[{"relation_name":"is_a","term_name":"primary viral infectious disease","termid":"MONDO:0100329"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Arenaviridae infectious disease","secondary_identifiers":["ICD9:078.89","EFO:0007150","DOID:3944","SCTID:3303004"],"synonyms":[{"name":"Arenaviridae caused disease or disorder","type":"exact"},{"name":"Arenaviridae disease or disorder","type":"exact"},{"name":"Arenaviridae infection","type":"related"},{"name":"arenavirus infection","type":"related"},{"name":"arenavirus infections","type":"related"},{"name":"arenavirus infectious disease","type":"exact"},{"name":"disease caused by arenavirus","type":"related"},{"name":"disease due to arenavirus","type":"exact"},{"name":"infection, Arenaviridae","type":"related"},{"name":"infection, arenavirus","type":"related"},{"name":"infections, Arenaviridae","type":"related"},{"name":"infections, arenavirus","type":"related"}],"termid":"MONDO:0005650","xrefs":{"Monarch":{"xref_id":"0005650"}}}


id: PBO:0062984
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PTGS2 antisense NFKB1 complex-mediated expression regulator RNA","termid":"PBO:0062984"}


id: FYPO:0004203
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of calcium ions into a cell occurs to a greater extent than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal calcium import","termid":"FYPO:0001953"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001985","FYPO:0000002","FYPO:0001320","FYPO:0000138"],"is_obsolete":false,"name":"increased calcium import","synonyms":[{"name":"increased calcium import during mitotic cell cycle","type":"related"},{"name":"increased calcium import during vegetative growth","type":"exact"},{"name":"increased calcium import into cell","type":"exact"},{"name":"increased calcium ion import","type":"exact"},{"name":"increased calcium ion import across plasma membrane","type":"exact"},{"name":"increased calcium uptake","type":"exact"},{"name":"increased calcium uptake into intracellular compartments","type":"related"},{"name":"increased cellular calcium import","type":"exact"}],"termid":"FYPO:0004203"}


id: PBO:0039158
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"adenylate kinase 4 pseudogene 5","termid":"PBO:0039158"}


id: GO:0034118
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of erythrocyte aggregation.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of homotypic cell-cell adhesion","termid":"GO:0034110"},{"relation_name":"regulates","term_name":"erythrocyte aggregation","termid":"GO:0034117"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0007155"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0007155","GO:0008150"],"is_obsolete":false,"name":"regulation of erythrocyte aggregation","synonyms":[{"name":"regulation of RBC aggregation","type":"exact"},{"name":"regulation of red blood cell aggregation","type":"exact"}],"termid":"GO:0034118"}


id: PBO:0041736
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CaM kinase like vesicle associated","termid":"PBO:0041736"}


id: PBO:0000470
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"1.14.13.70","termid":"PBO:0000470"}


id: FYPO:0007288
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein galactosylation is normal (i.e. indistinguishable from wild type). Protein galactosylation is the addition of a galactose residue to a protein amino acid.","definition_xrefs":["GO:0042125","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein glycosylation during vegetative growth","termid":"FYPO:0001909"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001312","FYPO:0001320","FYPO:0000257","FYPO:0000002"],"is_obsolete":false,"name":"normal protein galactosylation during vegetative growth","synonyms":[{"name":"normal protein galactosylation during mitotic cell cycle","type":"related"}],"termid":"FYPO:0007288"}


id: FYPO:0005199
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A regulation phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of a protein kinase activity occurs to a lower extent than normal.","definition_xrefs":["PomBase:mah","PMID:14739927"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal regulation of catalytic activity","termid":"FYPO:0004916"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0005447","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"decreased negative regulation of protein kinase activity","synonyms":[{"name":"decreased inhibition of protein kinase activity","type":"narrow"},{"name":"decreased negative regulation of protein kinase activity during mitotic cell cycle","type":"related"},{"name":"decreased negative regulation of protein kinase activity during vegetative growth","type":"exact"},{"name":"reduced negative regulation of protein kinase activity","type":"exact"}],"termid":"FYPO:0005199"}


id: GO:0042989
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The selective interaction of actin monomers with specific molecules that inhibit their polymerization by preventing their access to other monomers.","definition_xrefs":["GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete sequestering of actin monomers (obsolete GO:0042989)","synonyms":[{"name":"actin monomer retention","type":"exact"},{"name":"actin monomer sequestering","type":"exact"},{"name":"actin monomer sequestration","type":"exact"},{"name":"actin monomer storage","type":"exact"},{"name":"retention of actin monomers","type":"exact"},{"name":"sequestration of actin monomers","type":"exact"},{"name":"storage of actin monomers","type":"exact"}],"termid":"GO:0042989"}


id: MONDO:0019965
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. Any of the forms of ovarian benign neoplasm that have a rare incidence.","definition_xrefs":["MONDO:patterns/rare"],"gene_count":0,"genotype_count":0,"name":"obsolete rare benign ovarian tumor (obsolete MONDO:0019965)","secondary_identifiers":["Orphanet:97293"],"synonyms":[{"name":"rare ovarian benign neoplasm","type":"exact"}],"termid":"MONDO:0019965","xrefs":{"Monarch":{"xref_id":"0019965"}}}


id: PBO:0089858
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ER heat shock protein Lsh1","termid":"PBO:0089858"}


id: GO:0036429
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: adenosylcobinamide + ATP = adenosylcobinamide phosphate + ADP + H+.","definition_xrefs":["GOC:rynl"],"gene_count":0,"genotype_count":0,"name":"obsolete adenosylcobinamide kinase (ATP-specific) activity (obsolete GO:0036429)","termid":"GO:0036429"}


id: PBO:0027182
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_histone_H3-K9_dimethylation_at_centromere_outer_repeat","termid":"PBO:0027182"}


id: MONDO:0010978
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"portal vein, cavernous transformation of","secondary_identifiers":["MESH:C563407","UMLS:C1832917","MEDGEN:331396","OMIM:601004"],"synonyms":[{"name":"portal vein, cavernous transformation of","type":"exact"}],"termid":"MONDO:0010978","xrefs":{"Monarch":{"xref_id":"0010978"}}}


id: GO:0047077
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: O2 + ATP + Photinus luciferin = light + diphosphate + AMP + CO2 + oxidized Photinus luciferin.","definition_xrefs":["MetaCyc:1.13.12.7-RXN","EC:1.13.12.7"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)","termid":"GO:0016703"},{"relation_name":"is_a","term_name":"luciferin monooxygenase activity","termid":"GO:0045289"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity","secondary_identifiers":["RHEA:10732"],"synonyms":[{"name":"Photinus luciferin 4-monooxygenase (adenosine triphosphate-hydrolyzing)","type":"related"},{"name":"Photinus pyralis luciferase activity","type":"related"},{"name":"Photinus-luciferin 4-monooxygenase (ATP-hydrolysing)","type":"related"},{"name":"Photinus-luciferin:oxygen 4-oxidoreductase (decarboxylating, ATP-hydrolysing)","type":"related"},{"name":"firefly luciferase activity","type":"related"},{"name":"firefly luciferin luciferase activity","type":"related"},{"name":"luciferase (firefly luciferin)","type":"related"},{"name":"luciferase activity","type":"broad"}],"termid":"GO:0047077"}


id: SOFP:gbunit
data:
  {"annotation_feature_type":"gene","cv_name":"feature_property","definition":"Name of genbank scaffold sequence intersected by the feature","direct_ancestors":[{"relation_name":"is_a","term_name":"feature_property","termid":"SOFP:feature_property"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"gbunit","termid":"SOFP:gbunit"}


id: FYPO:0005728
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell cycle checkpoint phenotype in which deactivation of the mitotic spindle assembly checkpoint is normal (i.e. indistinguishable from wild type. The mitotic spindle assembly checkpoint normally delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.","definition_xrefs":["PMID:19592249","PomBase:vw","PMID:21664573","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal mitotic spindle assembly checkpoint","termid":"FYPO:0003762"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000298"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0001312","FYPO:0000298","FYPO:0000257","FYPO:0000002","FYPO:0000631"],"is_obsolete":false,"name":"normal deactivation of mitotic spindle assembly checkpoint","synonyms":[{"name":"normal deactivation of mitotic cell cycle spindle assembly checkpoint","type":"exact"},{"name":"normal mitotic spindle assembly checkpoint deactivation","type":"exact"},{"name":"normal mitotic spindle assembly checkpoint silencing","type":"exact"}],"termid":"FYPO:0005728"}


id: GO:1905664
data:
  {"annotated_genes":["SJAG_03631","SJAG_00296","SJAG_04551"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[112952,90688],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905949"},{"annotations":[101670],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905665"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of calcium ion import across plasma membrane.","definition_xrefs":["GO_REF:0000058","GOC:bhm","PMID:17640527","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of calcium ion import","termid":"GO:0090279"},{"relation_name":"is_a","term_name":"regulation of calcium ion transmembrane transport","termid":"GO:1903169"},{"relation_name":"regulates","term_name":"calcium ion import across plasma membrane","termid":"GO:0098703"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00296":null,"SJAG_03631":null,"SJAG_04551":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0055085"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0055085","GO:0008150"],"is_obsolete":false,"name":"regulation of calcium ion import across plasma membrane","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:1905664","terms_by_termid":{"GO:1905665":null,"GO:1905949":null}}


id: RO:HOM0000015
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"Structural homology that is detected at the level of the 3D protein structure, but maybe not at the level of the amino acid sequence.","direct_ancestors":[{"relation_name":"is_a","term_name":"in_structural_homology_relationship_with","termid":"RO:HOM0000006"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"in_protein_structural_homology_relationship_with","synonyms":[{"name":"protein structural homologous to","type":"exact"}],"termid":"RO:HOM0000015"}


id: PBO:0064777
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"diphosphoinositol pentakisphosphate kinase 2","termid":"PBO:0064777"}


id: PBO:0085048
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Non-essential protein of unconfirmed function; affects pre-rRNA processing, may act as a negative regulator of the transcription of genes involved in pseudohyphal growth; homologous to Srd1p","termid":"PBO:0085048"}


id: PBO:0067137
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 185, pseudogene","termid":"PBO:0067137"}


id: PR:O14228
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A phosphoribosylformylglycinamidine synthase that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO00539","PANTHER:PTHR10099:SF0","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphoribosylformylglycinamidine synthase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC6F12.10c","secondary_identifiers":["UniProtKB:O14228"],"synonyms":[{"name":"FGAM synthase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"FGAMS (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"FGAR amidotransferase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"FGAR-AT (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-PFAS","type":"exact"},{"name":"formylglycinamide ribonucleotide amidotransferase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"formylglycinamide ribotide amidotransferase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O14228"}


id: MONDO:0012502
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"familial tumoral calcinosis","termid":"MONDO:0018891"},{"relation_name":"is_a","term_name":"inborn errors of metabolism","termid":"MONDO:0019052"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066"],"is_obsolete":false,"name":"normophosphatemic familial tumoral calcinosis","secondary_identifiers":["OMIM:610455","GARD:10878","DOID:0080170","Orphanet:306658","UMLS:C1864861","MESH:C566473","MEDGEN:355311"],"synonyms":[{"name":"NFTC","type":"related"},{"name":"calcinosis, tumoral, with Normophosphatemia","type":"related"},{"name":"familial normophosphatemic tumoral calcinosis","type":"related"},{"name":"normophosphatemic familial tumoral calcinosis","type":"exact"},{"name":"tumoral calcinosis, familial, normophosphatemic","type":"exact"},{"name":"tumoral calcinosis, normophosphatemic, familial","type":"related"}],"termid":"MONDO:0012502","xrefs":{"Monarch":{"xref_id":"0012502"}}}


id: GO:1904769
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to isopentadecanoic acid.","definition_xrefs":["GOC:kmv","GOC:TermGenie","GO_REF:0000067","PMID:19828452"],"direct_ancestors":[{"relation_name":"is_a","term_name":"long-chain fatty acid binding","termid":"GO:0036041"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0008289"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0008289","GO:0003674","GO:0005488"],"is_obsolete":false,"name":"isopentadecanoic acid binding","synonyms":[{"name":"13-methylmyristic acid binding","type":"exact"}],"termid":"GO:1904769"}


id: MONDO:0018762
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Congenital hypopituitarism is characterized by multiple pituitary hormone deficiency, including somatotroph, thyrotroph, lactotroph, corticotroph or gonadotroph deficiencies, due to mutations of pituitary transcription factors involved in pituitary ontogenesis.","definition_xrefs":["Orphanet:467"],"direct_ancestors":[{"relation_name":"is_a","term_name":"non-acquired pituitary hormone deficiency","termid":"MONDO:0019824"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"non-acquired combined pituitary hormone deficiency","secondary_identifiers":["GARD:2252","ICD10CM:E23.0","MEDGEN:1842250","NANDO:2200312","UMLS:C5680091"],"synonyms":[{"name":"congenital combined pituitary hormone deficiency","type":"exact"},{"name":"congenital hypopituitarism","type":"exact"}],"termid":"MONDO:0018762","xrefs":{"Monarch":{"xref_id":"0018762"}}}


id: PBO:0058322
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4695","termid":"PBO:0058322"}


id: PATO:0001863
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A duration quality of a process inhering in a bearer by virtue of the bearer's having slow progressive course of indefinite duration.","definition_xrefs":["PATOC:cjm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"duration","termid":"PATO:0001309"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chronic","termid":"PATO:0001863"}


id: PBO:0089026
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"oligosaccharyltransferase epsilon subunit Ost2","termid":"PBO:0089026"}


id: PBO:0002951
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP-dependent DNA helicase Hrp3","termid":"PBO:0002951"}


id: PBO:0069446
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 711, pseudogene","termid":"PBO:0069446"}


id: FYPO:0000594
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of transposition is increased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal transposition","termid":"FYPO:0000591"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0005447","FYPO:0001320"],"is_obsolete":false,"name":"increased transposition","synonyms":[{"name":"increased transposable element transposition","type":"exact"},{"name":"increased transposition during mitotic cell cycle","type":"related"},{"name":"increased transposition during vegetative growth","type":"exact"},{"name":"transposable element transposition: increased","type":"related"}],"termid":"FYPO:0000594"}


id: PBO:0004899
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HC03 family inorganic anion exchanger (predicted)","termid":"PBO:0004899"}


id: FYPO:0002785
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which riboflavin binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal riboflavin binding","termid":"FYPO:0002388"},{"relation_name":"is_a","term_name":"abolished molecular function","termid":"FYPO:0005446"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000707"}],"interesting_parent_ids":["FYPO:0000652","FYPO:0000707","FYPO:0001985"],"is_obsolete":false,"name":"abolished riboflavin binding","synonyms":[{"name":"riboflavin binding abolished","type":"exact"}],"termid":"FYPO:0002785"}


id: PATO:0002400
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"Having a spindle-like shape that is wide in the middle and tapers at both ends.","definition_xrefs":["wikipedia:wikipedia"],"direct_ancestors":[{"relation_name":"is_a","term_name":"spindle-shaped","termid":"PATO:0001409"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fusiform","termid":"PATO:0002400"}


id: PBO:0088084
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UBX domain-containing substrate adaptor for Cdc48p; ubiquitin regulatory X domain-containing protein that acts as a substrate recruiting cofactor for Cdc48p; positively regulates Glc7p PPase activity to promote growth and mitotic progression in complex with Cdc48p; ubiquitinated protein interactor involved in ER-associated degradation (ERAD); regulated by nuclear Ub-dependent degradation (INMAD pathway) independent of the Asi and Doa10 complexes; homolog of human p47 (NSFL1C)","termid":"PBO:0088084"}


id: MONDO:0000300
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete tungiasis (obsolete MONDO:0000300)","termid":"MONDO:0000300","xrefs":{"Monarch":{"xref_id":"0000300"}}}


id: PBO:0028334
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_5-fluorouracil","termid":"PBO:0028334"}


id: GO:0050662
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Binding to a coenzyme, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.","definition_xrefs":["ISBN:0198506732"],"gene_count":0,"genotype_count":0,"name":"obsolete coenzyme binding (obsolete GO:0050662)","termid":"GO:0050662"}


id: MONDO:0800114
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A polyclonal hyperplasia of bronchiolar associated lymphoid tissue characterized by the development of lymphoid follicles with germinal centers in walls of the small airways.","definition_xrefs":["PMID:32040879"],"direct_ancestors":[{"relation_name":"is_a","term_name":"idiopathic interstitial pneumonia","termid":"MONDO:0002429"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"follicular bronchiolits","termid":"MONDO:0800114","xrefs":{"Monarch":{"xref_id":"0800114"}}}


id: PBO:0077709
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"troponin T2, cardiac type","termid":"PBO:0077709"}


id: GO:1902209
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of bacterial-type flagellum assembly.","definition_xrefs":["GOC:jl","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cell projection organization","termid":"GO:0031345"},{"relation_name":"is_a","term_name":"negative regulation of organelle assembly","termid":"GO:1902116"},{"relation_name":"is_a","term_name":"regulation of bacterial-type flagellum assembly","termid":"GO:1902208"},{"relation_name":"negatively_regulates","term_name":"bacterial-type flagellum assembly","termid":"GO:0044780"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0008150","GO:0044085"],"is_obsolete":false,"name":"negative regulation of bacterial-type flagellum assembly","synonyms":[{"name":"down regulation of bacterial flagellum assembly","type":"exact"},{"name":"down regulation of bacterial-type flagellum assembly","type":"exact"},{"name":"down-regulation of bacterial flagellum assembly","type":"exact"},{"name":"down-regulation of bacterial-type flagellum assembly","type":"exact"},{"name":"downregulation of bacterial flagellum assembly","type":"exact"},{"name":"downregulation of bacterial-type flagellum assembly","type":"exact"},{"name":"inhibition of bacterial flagellum assembly","type":"narrow"},{"name":"inhibition of bacterial-type flagellum assembly","type":"narrow"},{"name":"negative regulation of bacterial flagellum assembly","type":"exact"}],"termid":"GO:1902209"}


id: GO:0021915
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium.","definition_xrefs":["GO_REF:0000021","GOC:cls","GOC:dgh","GOC:jid","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tube development","termid":"GO:0035295"},{"relation_name":"is_a","term_name":"epithelium development","termid":"GO:0060429"},{"relation_name":"part_of","term_name":"nervous system development","termid":"GO:0007399"},{"relation_name":"part_of","term_name":"chordate embryonic development","termid":"GO:0043009"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"neural tube development","termid":"GO:0021915"}


id: MONDO:0001151
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A condition of mild to moderate high blood pressure that has no identifiable cause.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"essential hypertension","termid":"MONDO:0001134"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"benign essential hypertension","secondary_identifiers":["ICD9:401.1","MEDGEN:56371","SCTID:1201005","DOID:10913","UMLS:C0155583"],"synonyms":[{"name":"benign essential hypertension","type":"exact"}],"termid":"MONDO:0001151","xrefs":{"Monarch":{"xref_id":"0001151"}}}


id: PBO:0077482
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein 202","termid":"PBO:0077482"}


id: PBO:0026830
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_Lys63-specific_deubiquitinase_activity","termid":"PBO:0026830"}


id: PBO:0059257
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial ribosomal protein L22 pseudogene 1","termid":"PBO:0059257"}


id: MONDO:0015053
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hereditary angioedema type 1 (HAE 1) is a form of hereditary angioedema characterized by acute edema in subcutaneous tissues, viscera and/or the upper airway.","definition_xrefs":["Orphanet:100050"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary angioedema with C1Inh deficiency","termid":"MONDO:0033946"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"hereditary angioedema type 1","secondary_identifiers":["GARD:16933","ICD9:279.8","SCTID:234619000","MEDGEN:403466","UMLS:C2717906"],"synonyms":[{"name":"HAE 1","type":"exact"},{"name":"HAE-I","type":"exact"},{"name":"hereditary angioneurotic edema type 1","type":"exact"},{"name":"hereditary angioneurotic oedema type 1","type":"exact"}],"termid":"MONDO:0015053","xrefs":{"Monarch":{"xref_id":"0015053"}}}


id: PBO:0072201
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S18","termid":"PBO:0072201"}


id: GO:0036216
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus.","definition_xrefs":["PMID:7520444","PMID:18787413","GOC:uh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to stem cell factor","termid":"GO:0036215"},{"relation_name":"is_a","term_name":"cellular response to cytokine stimulus","termid":"GO:0071345"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to stem cell factor stimulus","synonyms":[{"name":"cellular response to KIT ligand","type":"exact"},{"name":"cellular response to KITLG","type":"exact"},{"name":"cellular response to SCF","type":"exact"},{"name":"cellular response to hematopoietic growth factor KL","type":"exact"}],"termid":"GO:0036216"}


id: PBO:0004810
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2.3.1.31","termid":"PBO:0004810"}


id: PBO:0084126
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Hexameric ring ATPase that remodels chromosome axis protein Hop1p; nucleolar component of the pachytene checkpoint, which prevents chromosome segregation when recombination and chromosome synapsis are defective; also represses meiotic interhomolog recombination in rDNA; required for meiotic double-stranded break formation","termid":"PBO:0084126"}


id: PBO:0041231
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 1 open reading frame 53","termid":"PBO:0041231"}


id: PBO:0046160
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"E74 like ETS transcription factor 2","termid":"PBO:0046160"}


id: PBO:0081561
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 485","termid":"PBO:0081561"}


id: PBO:0005880
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"intronic ORF","termid":"PBO:0005880"}


id: PBO:0031904
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/threonine protein kinase Tor1","termid":"PBO:0031904"}


id: PBO:0079170
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TSPO associated protein 1","termid":"PBO:0079170"}


id: PBO:0074754
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, H/ACA box 113","termid":"PBO:0074754"}


id: MONDO:0005849
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. Allergic reaction to milk (usually cow's milk) or milk products. milk hypersensitivity should be differentiated from lactose intolerance, an intolerance to milk as a result of congenital deficiency of lactase.","definition_xrefs":["MESH:D016269"],"gene_count":0,"genotype_count":0,"name":"obsolete milk allergic reaction (obsolete MONDO:0005849)","secondary_identifiers":["DOID:4376"],"synonyms":[{"name":"milk allergic reaction","type":"exact"},{"name":"milk allergy","type":"related"}],"termid":"MONDO:0005849","xrefs":{"Monarch":{"xref_id":"0005849"}}}


id: GO:0051500
data:
  {"annotated_genes":["SJAG_01248"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[75344],"is_not":false,"summary":null,"term":"GO:0051500"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: D-tyrosyl-tRNATyr + H2O = D-tyrosine + tRNATyr. Removal of a D-tyrosine from a charged tRNA(Tyr).","definition_xrefs":["RHEA:25347","PMID:14527667"],"direct_ancestors":[{"relation_name":"is_a","term_name":"D-aminoacyl-tRNA deacylase activity","termid":"GO:0051499"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01248":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0140101"},{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016787","GO:0003674","GO:0140101","GO:0140098","GO:0003824","GO:0016788"],"is_obsolete":false,"name":"D-tyrosyl-tRNA(Tyr) deacylase activity","references_by_uniquename":{"GO_REF:0000033":null},"termid":"GO:0051500","terms_by_termid":{"GO:0051500":null}}


id: FYECO:0000138
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"Experiments were performed in rich medium containing glycerol as the sole carbon source, yeast extract and other components. The concentration of glycerol is typically around 2-3% and supplemented with trace amounts of another carbon source (e.g. glucose).","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping rich medium","termid":"FYECO:0000080"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glycerol YE","secondary_identifiers":["FYECO:0000083"],"synonyms":[{"name":"glycerol rich medium","type":"broad"},{"name":"glycerol sole carbon source YE","type":"related"},{"name":"glycerol sole carbon source rich medium","type":"exact"},{"name":"non-fermentable glycerol sole carbon source rich medium","type":"exact"},{"name":"nonfermentable glycerol sole carbon source rich medium","type":"related"}],"termid":"FYECO:0000138"}


id: MONDO:0022397
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete retinal ciliopathy due to mutation in the retinitis pigmentosa-1 gene (obsolete MONDO:0022397)","secondary_identifiers":["Orphanet:156168"],"termid":"MONDO:0022397","xrefs":{"Monarch":{"xref_id":"0022397"}}}


id: MONDO:0006686
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Infarctions that occur in the brain stem which is comprised of the midbrain; pons; and medulla oblongata. There are several named syndromes characterized by their distinctive clinical manifestations and specific sites of ischemic injury.","definition_xrefs":["MESH:D020526"],"direct_ancestors":[{"relation_name":"is_a","term_name":"brain infarction","termid":"MONDO:0005394"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"brain stem infarction","secondary_identifiers":["ICD9:434.91","SCTID:95457000","DOID:3523","EFO:1000847","MEDGEN:101068","UMLS:C0521542"],"synonyms":[{"name":"brain infarction of brainstem","type":"exact"},{"name":"brainstem brain infarction","type":"exact"},{"name":"brainstem infarction","type":"exact"}],"termid":"MONDO:0006686","xrefs":{"Monarch":{"xref_id":"0006686"}}}


id: MOD:01730
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces the N6'-hydrogen atom of a lysine residue with the Proteome Sciences TMT6plex-127 reporter+balance group.","definition_xrefs":["Unimod:737#K"],"direct_ancestors":[{"relation_name":"is_a","term_name":"TMT6plex reporter+balance reagent N-acylated residue","termid":"MOD:01717"},{"relation_name":"is_a","term_name":"TMT6plex-127 reporter+balance reagent acylated residue","termid":"MOD:01728"},{"relation_name":"is_a","term_name":"N6-acylated L-lysine","termid":"MOD:01875"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:01875"}],"interesting_parent_ids":["MOD:01875"],"is_obsolete":false,"name":"TMT6plex-127 reporter+balance reagent N6-acylated lysine","synonyms":[{"name":"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl","type":"exact"},{"name":"Sixplex Tandem Mass Tag(TM)","type":"related"},{"name":"TMT6plex","type":"related"}],"termid":"MOD:01730"}


id: PBO:0050206
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"high mobility group nucleosome binding domain 1 pseudogene 23","termid":"PBO:0050206"}


id: MONDO:0005245
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete testicular seminoma (obsolete MONDO:0005245)","synonyms":[{"name":"obsolete testicular seminoma (disease)","type":"exact"}],"termid":"MONDO:0005245","xrefs":{"Monarch":{"xref_id":"0005245"}}}


id: PBO:0077287
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein 30B","termid":"PBO:0077287"}


id: PBO:0080290
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vomeronasal 1 receptor 54 pseudogene","termid":"PBO:0080290"}


id: PBO:0076358
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"synaptotagmin like 5","termid":"PBO:0076358"}


id: PBO:0027616
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-monopolar_mitotic_spindle_following_normal_mitosis","termid":"PBO:0027616"}


id: GO:0072725
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4-nitroquinoline N-oxide stimulus.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to 4-nitroquinoline N-oxide","termid":"GO:0072724"},{"relation_name":"is_a","term_name":"cellular response to nitrogen compound","termid":"GO:1901699"},{"relation_name":"is_a","term_name":"cellular response to oxygen-containing compound","termid":"GO:1901701"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to 4-nitroquinoline N-oxide","termid":"GO:0072725"}


id: MONDO:0003182
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Anterior horn disease is one of a number of medical disorders affecting the anterior horn of the spinal cord. Anterior horn diseases include spinal muscular atrophy, poliomyelitis and amyotrophic lateral sclerosis.","definition_xrefs":["Wikipedia:Anterior_horn_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"spinal cord disorder","termid":"MONDO:0002545"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"anterior horn disorder","secondary_identifiers":["SCTID:85672005","MEDGEN:102314","UMLS:C0154681","DOID:4873","ICD9:335","ICD9:335.9","MESH:D016472"],"synonyms":[{"name":"disease of ventral horn of spinal cord","type":"exact"},{"name":"disease or disorder of ventral horn of spinal cord","type":"exact"},{"name":"disorder of ventral horn of spinal cord","type":"exact"},{"name":"ventral horn of spinal cord disease","type":"exact"},{"name":"ventral horn of spinal cord disease or disorder","type":"exact"}],"termid":"MONDO:0003182","xrefs":{"Monarch":{"xref_id":"0003182"}}}


id: GO:0030573
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bile acid metabolic process","termid":"GO:0008206"},{"relation_name":"is_a","term_name":"monocarboxylic acid catabolic process","termid":"GO:0072329"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006629","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"bile acid catabolic process","secondary_identifiers":["GO:0019613"],"synonyms":[{"name":"bile acid 7alpha-dehydroxylation pathway","type":"narrow"},{"name":"bile acid breakdown","type":"exact"},{"name":"bile acid catabolism","type":"exact"},{"name":"bile acid degradation","type":"exact"},{"name":"cholate catabolic process","type":"narrow"}],"termid":"GO:0030573"}


id: PBO:0090930
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/threonine protein phosphatase (calcipressin) regulatory subunit Rcn1","termid":"PBO:0090930"}


id: GO:0009940
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to an amino terminal propeptide, which functions as a sorting signal to sort away the soluble vacuolar protein from Golgi to lytic vacuole via clathrin-coated vesicles.","definition_xrefs":["GOC:sm","PMID:10871276"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vacuolar sorting signal binding","termid":"GO:0010209"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0005048"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005048","GO:0005488"],"is_obsolete":false,"name":"amino-terminal vacuolar sorting propeptide binding","termid":"GO:0009940"}


id: MONDO:0004027
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete embryonal cancer (obsolete MONDO:0004027)","termid":"MONDO:0004027","xrefs":{"Monarch":{"xref_id":"0004027"}}}


id: GO:0005811
data:
  {"annotated_genes":["SJAG_03604","SJAG_02980","SJAG_03609","SJAG_03360","SJAG_03909","SJAG_02907","SJAG_00624","SJAG_02161","SJAG_03471","SJAG_02487","SJAG_01036","SJAG_02163","SJAG_04973","SJAG_02089","SJAG_04532","SJAG_02543","SJAG_04041","SJAG_03235"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[67801,72677,73244,75723,75757,76195,79053,80658,89496,89576,91370,94132,97185,97274,97972,113780,114389,117191],"is_not":false,"summary":null,"term":"GO:0005811"}]},"cv_name":"cellular_component","definition":"An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.","definition_xrefs":["GOC:tb","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracellular membraneless organelle","termid":"GO:0043232"}],"gene_count":18,"genes_by_uniquename":{"SJAG_00624":null,"SJAG_01036":null,"SJAG_02089":null,"SJAG_02161":null,"SJAG_02163":null,"SJAG_02487":null,"SJAG_02543":null,"SJAG_02907":null,"SJAG_02980":null,"SJAG_03235":null,"SJAG_03360":null,"SJAG_03471":null,"SJAG_03604":null,"SJAG_03609":null,"SJAG_03909":null,"SJAG_04041":null,"SJAG_04532":null,"SJAG_04973":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"lipid droplet","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"adiposome","type":"exact"},{"name":"lipid body","type":"exact"},{"name":"lipid particle","type":"exact"}],"termid":"GO:0005811","terms_by_termid":{"GO:0005811":null}}


id: PBO:0040013
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"armadillo repeat containing 2","termid":"PBO:0040013"}


id: PBO:0064168
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phospholipase A2 group IVE","termid":"PBO:0064168"}


id: PBO:0079747
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UCHL1 divergent transcript","termid":"PBO:0079747"}


id: MONDO:0001910
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A disorder characterized by bluish-black discoloration of the cartilaginous tissues due to accumulation of homogentisic acid. It is associated with alkaptonuria. Signs and symptoms include dark urine, skin pigmentation, and arthritis.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"connective tissue disorder","termid":"MONDO:0003900"},{"relation_name":"is_a","term_name":"skeletal system disorder","termid":"MONDO:0005172"},{"relation_name":"is_a","term_name":"disorder of organic acid metabolism","termid":"MONDO:0045022"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066"],"is_obsolete":false,"name":"ochronosis disorder","secondary_identifiers":["MESH:D009794","HP:0030764","MEDGEN:45177","NCIT:C84938","DOID:14223","ICD9:270.2","SCTID:410042009","UMLS:C0028817"],"synonyms":[{"name":"ochronosis","type":"exact"}],"termid":"MONDO:0001910","xrefs":{"Monarch":{"xref_id":"0001910"}}}


id: GO:0043308
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The regulated exocytosis of secretory granules containing preformed mediators such as major basic protein, eosinophil peroxidase, and eosinophil cationic protein by an eosinophil.","definition_xrefs":["ISBN:0781735149"],"direct_ancestors":[{"relation_name":"is_a","term_name":"leukocyte degranulation","termid":"GO:0043299"},{"relation_name":"part_of","term_name":"eosinophil activation involved in immune response","termid":"GO:0002278"},{"relation_name":"part_of","term_name":"eosinophil mediated immunity","termid":"GO:0002447"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016192"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0051179","GO:0008150","GO:0006810","GO:0016192"],"is_obsolete":false,"name":"eosinophil degranulation","synonyms":[{"name":"eosinophil granule exocytosis","type":"exact"}],"termid":"GO:0043308"}


id: MONDO:0002147
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete Coffin-Siris syndrome (obsolete MONDO:0002147)","termid":"MONDO:0002147","xrefs":{"Monarch":{"xref_id":"0002147"}}}


id: GO:0015891
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"iron coordination entity transport","termid":"GO:1901678"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0051179","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"siderophore transport","secondary_identifiers":["GO:0015892"],"synonyms":[{"name":"iron-siderochrome transport","type":"narrow"},{"name":"iron-siderophore transport","type":"exact"},{"name":"siderochrome transport","type":"narrow"},{"name":"siderophore-iron transport","type":"exact"}],"termid":"GO:0015891"}


id: GO:0102001
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-isoleucine + 2 O2 + 2 NADPH(4-) + 2 H+ = (E)-2-methylbutanal oxime + 2 NADP(3-) + carbon dioxide + 3 H2O.","definition_xrefs":["EC:1.14.14.39"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen","termid":"GO:0016709"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0016491","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"isoleucine N-monooxygenase (oxime forming) activity","secondary_identifiers":["RHEA:28602","MetaCyc:1.14.13.117-RXN"],"termid":"GO:0102001"}


id: PBO:0076089
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"STT3 oligosaccharyltransferase complex catalytic subunit B","termid":"PBO:0076089"}


id: PBO:0051569
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"interleukin 15","termid":"PBO:0051569"}


id: PBO:0040597
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BAG1 pseudogene 1","termid":"PBO:0040597"}


id: PBO:0057305
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 515-2","termid":"PBO:0057305"}


id: GO:0060999
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of developmental process","termid":"GO:0051094"},{"relation_name":"is_a","term_name":"regulation of dendritic spine development","termid":"GO:0060998"},{"relation_name":"positively_regulates","term_name":"dendritic spine development","termid":"GO:0060996"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of dendritic spine development","termid":"GO:0060999"}


id: GO:0075163
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G-protein beta subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:pamgo_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of G-protein beta subunit-mediated signal transduction in response to host (obsolete GO:0075163)","synonyms":[{"name":"positive regulation of symbiont G-protein beta subunit-mediated signal transduction in response to host","type":"exact"}],"termid":"GO:0075163"}


id: MONDO:0011495
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete Langerhans-cell histiocytosis (obsolete MONDO:0011495)","termid":"MONDO:0011495","xrefs":{"Monarch":{"xref_id":"0011495"}}}


id: PBO:0074326
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2","termid":"PBO:0074326"}


id: GO:0030441
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:mcc"],"gene_count":0,"genotype_count":0,"name":"obsolete activation of MAPKKK during sporulation (sensu Fungi) (obsolete GO:0030441)","synonyms":[{"name":"activation of MAPKKK during sporulation (sensu Fungi)","type":"exact"}],"termid":"GO:0030441"}


id: GO:1904188
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of transformation of host cell by virus.","definition_xrefs":["GO_REF:0000058","GOC:TermGenie","PMID:12200142"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of biological process","termid":"GO:0048519"},{"relation_name":"is_a","term_name":"regulation of transformation of host cell by virus","termid":"GO:1904187"},{"relation_name":"negatively_regulates","term_name":"symbiont-mediated transformation of host cell","termid":"GO:0019087"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of transformation of host cell by virus","synonyms":[{"name":"down regulation of transformation of host cell by virus","type":"exact"},{"name":"down regulation of viral transformation","type":"exact"},{"name":"down regulation of viral transformation of host cell","type":"exact"},{"name":"down-regulation of transformation of host cell by virus","type":"exact"},{"name":"down-regulation of viral transformation","type":"exact"},{"name":"down-regulation of viral transformation of host cell","type":"exact"},{"name":"downregulation of transformation of host cell by virus","type":"exact"},{"name":"downregulation of viral transformation","type":"exact"},{"name":"downregulation of viral transformation of host cell","type":"exact"},{"name":"inhibition of transformation of host cell by virus","type":"narrow"},{"name":"inhibition of viral transformation","type":"narrow"},{"name":"inhibition of viral transformation of host cell","type":"narrow"},{"name":"negative regulation of viral transformation","type":"exact"},{"name":"negative regulation of viral transformation of host cell","type":"exact"}],"termid":"GO:1904188"}


id: PATO:0001761
data:
  {"annotation_feature_type":"gene","cv_name":"quality","direct_ancestors":[{"relation_name":"is_a","term_name":"semi-fertile","termid":"PATO:0001767"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"male semi-fertile","termid":"PATO:0001761"}


id: PBO:0069391
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 651, pseudogene","termid":"PBO:0069391"}


id: PBO:0120018
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dynein regulatory complex subunit 11 like","termid":"PBO:0120018"}


id: PBO:0067567
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 720, pseudogene","termid":"PBO:0067567"}


id: GO:0032577
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the transfer of a linoleoyl ((9Z,12Z)-octadeca-9,12-dienoyl) group from phosphatidylcholine to an oxygen atom on a cardiolipin molecule.","definition_xrefs":["GOC:cb","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"O-linoleoyltransferase activity","termid":"GO:0032576"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0016740","GO:0003674","GO:0003824","GO:0016746"],"is_obsolete":false,"name":"phosphatidylcholine:cardiolipin O-linoleoyltransferase activity","synonyms":[{"name":"phosphatidylcholine:cardiolipin linoleoyltransferase","type":"exact"}],"termid":"GO:0032577"}


id: PBO:0054080
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1430","termid":"PBO:0054080"}


id: PBO:0082808
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of yeast cortical actin cytoskeleton; binds and cross links actin filaments; originally identified by its homology to calponin (contains a calponin-like repeat) but the Scp1p domain structure is more similar to transgelin","termid":"PBO:0082808"}


id: GO:0043030
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency or rate of macrophage activation.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of leukocyte activation","termid":"GO:0002694"},{"relation_name":"regulates","term_name":"macrophage activation","termid":"GO:0042116"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of macrophage activation","synonyms":[{"name":"regulation of macrophage polarization","type":"exact"}],"termid":"GO:0043030"}


id: FYPO:0001084
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of alpha-D-glucan measured in the cell wall is greater than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased cell wall polysaccharide level","termid":"FYPO:0004859"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001985","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"increased cell wall alpha-glucan level","synonyms":[{"name":"increased cell wall alpha-D-glucan level","type":"exact"},{"name":"increased cell wall alpha-glucan accumulation","type":"related"},{"name":"increased cell wall alpha-glucan level during mitotic cell cycle","type":"related"},{"name":"increased cell wall alpha-glucan level during vegetative growth","type":"exact"}],"termid":"FYPO:0001084"}


id: GO:0072586
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binds to and modulates the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"enzyme regulator activity","termid":"GO:0030234"},{"relation_name":"is_a","term_name":"ATPase regulator activity","termid":"GO:0060590"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0098772"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0030234"}],"interesting_parent_ids":["GO:0003674","GO:0030234","GO:0098772"],"is_obsolete":false,"name":"DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity","termid":"GO:0072586"}


id: GO:0048036
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the central complex over time, from its formation to the mature structure. The central complex region of the insect brain is thought to be crucial for control of locomotive behavior. Located in the middle of the two protocerebral hemispheres, it comprises four neuropilar regions, the fan-shaped body, the ellipsoid body, the protocerebral bridge and the paired noduli.","definition_xrefs":["PMID:12490252"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure development","termid":"GO:0048856"},{"relation_name":"part_of","term_name":"brain development","termid":"GO:0007420"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"central complex development","synonyms":[{"name":"central body development","type":"exact"}],"termid":"GO:0048036"}


id: GO:0090650
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose.","definition_xrefs":["PMID:21525936","GOC:sl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to nutrient levels","termid":"GO:0031669"},{"relation_name":"is_a","term_name":"cellular response to decreased oxygen levels","termid":"GO:0036294"},{"relation_name":"is_a","term_name":"response to oxygen-glucose deprivation","termid":"GO:0090649"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to oxygen-glucose deprivation","synonyms":[{"name":"cellular response to OGD","type":"exact"}],"termid":"GO:0090650"}


id: GO:0005042
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.","definition_xrefs":["PMID:15960985","GOC:dph","GOC:signaling"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transmembrane signaling receptor activity","termid":"GO:0004888"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0038023"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0038023","GO:0003674"],"is_obsolete":false,"name":"netrin receptor activity","termid":"GO:0005042"}


id: PBO:0000253
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"calcium channel regulatory subunit Yam8","termid":"PBO:0000253"}


id: PBO:0040522
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"AZGP1 pseudogene 2","termid":"PBO:0040522"}


id: PBO:0051448
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin lambda variable 4-60","termid":"PBO:0051448"}


id: GO:0019888
data:
  {"annotated_genes":["SJAG_03309","SJAG_00078","SJAG_04999","SJAG_03940","SJAG_04968","SJAG_00369","SJAG_01270","SJAG_00095","SJAG_03793","SJAG_03353","SJAG_00229","SJAG_02380","SJAG_04638","SJAG_01901","SJAG_03681","SJAG_01142","SJAG_00534","SJAG_00526","SJAG_04871","SJAG_03272","SJAG_04627"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[70041,80033,92458,95829],"is_not":false,"summary":null,"term":"GO:0019888"},{"annotations":[88184,74814],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008597"},{"annotations":[114582,76491,78280,92404,80668,117562,97207,74390],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0072542"},{"annotations":[72053,88843],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004864"},{"annotations":[77822,76372,87304],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004865"},{"annotations":[73471,77603],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008160"}]},"cv_name":"molecular_function","definition":"Binds to and modulates the activity of a protein phosphatase.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphatase regulator activity","termid":"GO:0019208"}],"gene_count":21,"genes_by_uniquename":{"SJAG_00078":null,"SJAG_00095":null,"SJAG_00229":null,"SJAG_00369":null,"SJAG_00526":null,"SJAG_00534":null,"SJAG_01142":null,"SJAG_01270":null,"SJAG_01901":null,"SJAG_02380":null,"SJAG_03272":null,"SJAG_03309":null,"SJAG_03353":null,"SJAG_03681":null,"SJAG_03793":null,"SJAG_03940":null,"SJAG_04627":null,"SJAG_04638":null,"SJAG_04871":null,"SJAG_04968":null,"SJAG_04999":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0030234"},{"rel_name":"is_a","termid":"GO:0098772"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0098772","GO:0003674","GO:0030234"],"is_obsolete":false,"name":"protein phosphatase regulator activity","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["GO:0008599","GO:0008601","GO:0030359","GO:0030362","Reactome:R-HSA-180038"],"synonyms":[{"name":"calcineurin regulator activity","type":"narrow"},{"name":"calcineurin, intrinsic regulator activity","type":"narrow"},{"name":"protein phosphatase 2 regulator activity","type":"narrow"},{"name":"protein phosphatase 2, intrinsic regulator activity","type":"narrow"},{"name":"protein phosphatase 3 regulator activity","type":"narrow"},{"name":"protein phosphatase 3, intrinsic regulator activity","type":"narrow"},{"name":"protein phosphatase type 1 regulator activity","type":"narrow"},{"name":"protein phosphatase type 1, intrinsic regulator activity","type":"narrow"},{"name":"protein phosphatase type 2A regulator activity","type":"narrow"},{"name":"protein phosphatase type 2A, intrinsic regulator activity","type":"narrow"},{"name":"protein phosphatase type 2B regulator activity","type":"narrow"},{"name":"protein phosphatase type 2B, intrinsic regulator activity","type":"narrow"},{"name":"protein phosphatase type 4 regulator activity","type":"narrow"},{"name":"protein phosphatase type 4, intrinsic regulator activity","type":"narrow"}],"termid":"GO:0019888","terms_by_termid":{"GO:0004864":null,"GO:0004865":null,"GO:0008160":null,"GO:0008597":null,"GO:0019888":null,"GO:0072542":null}}


id: PBO:0058606
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 6738","termid":"PBO:0058606"}


id: PBO:0035854
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_histone_H2A_phosphorylation_at_nucleosome-depleted_regions_during_vegetative_growth","termid":"PBO:0035854"}


id: PBO:0044520
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DAB adaptor protein 1","termid":"PBO:0044520"}


id: GO:0018192
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The formation of an enzyme active site via modification of peptidyl-cysteine to peptidyl-L-cysteine persulfide.","definition_xrefs":["RESID:AA0269"],"gene_count":0,"genotype_count":0,"name":"obsolete enzyme active site formation via cysteine modification to L-cysteine persulfide (obsolete GO:0018192)","synonyms":[{"name":"enzyme active site formation via L-cysteine persulphide","type":"exact"}],"termid":"GO:0018192"}


id: FYECO:0000432
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"Experiments were performed in rich medium containing galactose as the carbon source, yeast extract and other components. The concentration of galactose is typically around 2%.","definition_xrefs":["PomBase:mlr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping rich medium","termid":"FYECO:0000080"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"galactose YE","synonyms":[{"name":"galactose rich medium","type":"broad"}],"termid":"FYECO:0000432"}


id: GO:0052888
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: (S)-dihydroorotate + fumarate = orotate + succinate.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete dihydroorotate oxidase (fumarate) activity (obsolete GO:0052888)","synonyms":[{"name":"DHOD activity","type":"broad"},{"name":"DHOdase activity","type":"broad"},{"name":"DHodehase activity","type":"broad"},{"name":"dihydoorotic acid dehydrogenase activity","type":"broad"},{"name":"dihydroorotate dehydrogenase activity","type":"broad"},{"name":"dihydroorotate oxidase (fumarate) activity","type":"exact"},{"name":"dihydroorotate oxidase activity","type":"broad"}],"termid":"GO:0052888"}


id: PBO:0067098
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 138, pseudogene","termid":"PBO:0067098"}


id: PBO:0059995
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-ND4L pseudogene 15","termid":"PBO:0059995"}


id: GO:0046465
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving dolichyl diphosphate, a diphosphorylated dolichol derivative. In eukaryotes, these function as carriers of mono- and oligosaccharide residues in the glycosylation of lipids and proteins within intracellular membranes.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phospholipid metabolic process","termid":"GO:0006644"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0006629"],"is_obsolete":false,"name":"dolichyl diphosphate metabolic process","synonyms":[{"name":"dolichyl diphosphate metabolism","type":"exact"}],"termid":"GO:0046465"}


id: MONDO:0007636
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Frontorhiny is a distinct syndromic type of frontonasal malformation characterized by hypertelorism, wide nasal bridge, broad columella, widened philtrum, widely separated narrow nares, poor development of nasal tip, midline notch of the upper alveolus, columella base swellings and a low hairline. Additional features reported in some include upper eyelid ptosis and midline dermoid cysts of craniofacial structures and philtral pits or rugose folding behind the ears. An autosomal recessive inheritance has been proposed.","definition_xrefs":["Orphanet:391474"],"direct_ancestors":[{"relation_name":"is_a","term_name":"frontonasal dysplasia","termid":"MONDO:0016643"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"frontorhiny","secondary_identifiers":["DOID:0081045","NCIT:C129028","UMLS:C5574965","MEDGEN:1803615","GARD:12642","OMIM:136760"],"synonyms":[{"name":"ALX3-related frontonasal dysplasia","type":"exact"},{"name":"FND1","type":"related"},{"name":"frontonasal dysplasia","type":"related"},{"name":"frontonasal dysplasia 1","type":"related"},{"name":"frontonasal dysplasia type 1","type":"exact"},{"name":"frontonasal malformation","type":"related"},{"name":"frontorhiny","type":"exact"},{"name":"isolated median cleft face syndrome","type":"exact"},{"name":"isolated median cleft syndrome","type":"related"},{"name":"median Facial cleft syndrome","type":"related"}],"termid":"MONDO:0007636","xrefs":{"Monarch":{"xref_id":"0007636"}}}


id: PBO:0084648
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for prospore membrane development and the production of outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p; activated by Cak1p-mediated phosphorylation of threonine (T207) in the activation loop during meiosis I followed by Ssp2p-promoted autophosphorylation of tyrosine (T209) during meiosis II","termid":"PBO:0084648"}


id: MONDO:0022444
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Amyloidosis with tracheobronchial deposits in diffuse plaques that can cause stenosis or parenchymal nodules or masses.","definition_xrefs":["PMID:22197156"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amyloidosis","termid":"MONDO:0019065"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0021179"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0021179"],"is_obsolete":false,"name":"amyloidosis bronchopulmonary","secondary_identifiers":["GARD:1026"],"termid":"MONDO:0022444","xrefs":{"Monarch":{"xref_id":"0022444"}}}


id: PBO:0000404
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Erd1 homolog (predicted)","termid":"PBO:0000404"}


id: PR:Q10335
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A 26S proteasome non-ATPase regulatory subunit 6 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO02451","PANTHER:PTHR14145:SF1","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"26S proteasome regulatory subunit rpn7 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC582.07c","secondary_identifiers":["UniProtKB:Q10335"],"synonyms":[{"name":"Spom972h-PSMD6","type":"exact"}],"termid":"PR:Q10335"}


id: PBO:0004926
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tetra spanning protein 1, Tts1","termid":"PBO:0004926"}


id: PBO:0045342
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"docking protein 2","termid":"PBO:0045342"}


id: PBO:0045600
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"double homeobox 4 like 11 (pseudogene)","termid":"PBO:0045600"}


id: PR:Q10273
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC13G7.09c gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q10273"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C13G7.09c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC13G7.09c","synonyms":[{"name":"Spom972h-SPAC13G7.09c","type":"exact"}],"termid":"PR:Q10273"}


id: PBO:0041816
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"capping protein regulator and myosin 1 linker 2","termid":"PBO:0041816"}


id: PBO:0058374
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4746","termid":"PBO:0058374"}


id: PBO:0048712
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glutaredoxin 3 pseudogene 1","termid":"PBO:0048712"}


id: PBO:0043637
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coordinator of PRMT5 and differentiation stimulator","termid":"PBO:0043637"}


id: PBO:0002671
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PPPDE peptidase family (predicted)","termid":"PBO:0002671"}


id: GO:0099145
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of exocytic fusion of neurotransmitter receptor containing vesicles into the postsynaptic membrane.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of exocytosis","termid":"GO:0017157"},{"relation_name":"is_a","term_name":"regulation of protein transport","termid":"GO:0051223"},{"relation_name":"is_a","term_name":"regulation of biological quality","termid":"GO:0065008"},{"relation_name":"is_a","term_name":"regulation of receptor localization to synapse","termid":"GO:1902683"},{"relation_name":"is_a","term_name":"regulation of protein localization to cell periphery","termid":"GO:1904375"},{"relation_name":"is_a","term_name":"regulation of protein localization to membrane","termid":"GO:1905475"},{"relation_name":"regulates","term_name":"exocytic insertion of neurotransmitter receptor to postsynaptic membrane","termid":"GO:0098967"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0016192"}],"interesting_parent_ids":["GO:0008150","GO:0006810","GO:0016192"],"is_obsolete":false,"name":"regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane","termid":"GO:0099145"}


id: PBO:0053789
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1040","termid":"PBO:0053789"}


id: MONDO:0021513
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign neoplasm that involves the tonsil.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"respiratory system benign neoplasm","termid":"MONDO:0000382"},{"relation_name":"is_a","term_name":"tonsil neoplasm","termid":"MONDO:0021250"},{"relation_name":"is_a","term_name":"benign neoplasm of pharynx","termid":"MONDO:0021523"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"benign neoplasm of tonsil","secondary_identifiers":["icd11.foundation:2132438112","ICD10CM:D10.4","NCIT:C3594","MEDGEN:57804","SCTID:92263001","UMLS:C0153936","ICD9:210.5"],"synonyms":[{"name":"benign neoplasm of the tonsil","type":"exact"},{"name":"benign tonsil neoplasm","type":"exact"},{"name":"benign tonsil tumor","type":"exact"},{"name":"benign tonsil tumour","type":"exact"},{"name":"benign tonsillar neoplasm","type":"exact"},{"name":"benign tonsillar tumor","type":"exact"},{"name":"benign tonsillar tumour","type":"exact"},{"name":"benign tumor of the tonsil","type":"exact"},{"name":"benign tumor of tonsil","type":"exact"},{"name":"benign tumour of the tonsil","type":"exact"},{"name":"benign tumour of tonsil","type":"exact"},{"name":"tonsil benign neoplasm","type":"exact"},{"name":"tonsillar neoplasm, benign","type":"exact"}],"termid":"MONDO:0021513","xrefs":{"Monarch":{"xref_id":"0021513"}}}


id: _global:has_part
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"Inverse of part_of.","direct_ancestors":[{"relation_name":"is_a","term_name":"overlaps","termid":"_global:overlaps"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"has_part","secondary_identifiers":["BFO:0000051"],"synonyms":[{"name":"has part","type":"exact"}],"termid":"_global:has_part"}


id: PBO:0066821
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RN7SK pseudogene 120","termid":"PBO:0066821"}


id: MONDO:0016133
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete rare hereditary metabolic disease with peripheral neuropathy (obsolete MONDO:0016133)","secondary_identifiers":["Orphanet:207018"],"termid":"MONDO:0016133","xrefs":{"Monarch":{"xref_id":"0016133"}}}


id: PBO:0089808
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphoserine aminotransferase","termid":"PBO:0089808"}


id: FYPO:0005077
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell morphology phenotype in which a cell becomes elongated, i.e. has a greater length and length:diameter ratio than normal, when the cell is subject to glucose starvation.","definition_xrefs":["PomBase:mah","PMID:17179073"],"direct_ancestors":[{"relation_name":"is_a","term_name":"elongated cell","termid":"FYPO:0000017"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000005"},{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"has_part","termid":"FYPO:0000005"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000005","FYPO:0000002"],"is_obsolete":false,"name":"elongated cell during glucose starvation","synonyms":[{"name":"cell morphology, elongated cell during glucose starvation","type":"exact"},{"name":"elongated cell during glucose depletion","type":"exact"},{"name":"elongated cell during glucose deprivation","type":"exact"},{"name":"long cell during glucose starvation","type":"exact"}],"termid":"FYPO:0005077"}


id: FYPO:0007882
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of a protein kinase activity is normal (i.e. indistinguishable from wild type) during a cellular response to methyl methanesulfonate.","definition_xrefs":["PomBase:mah","PMID:34608864"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein kinase activity","termid":"FYPO:0003075"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000652"}],"interesting_parent_ids":["FYPO:0000654","FYPO:0000257","FYPO:0000652"],"is_obsolete":false,"name":"normal protein kinase activity during cellular response to methyl methanesulfonate","synonyms":[{"name":"normal protein kinase activity during cellular response to MMS","type":"exact"}],"termid":"FYPO:0007882"}


id: _global:different_in_magnitude_relative_to
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"q1 different_in_magnitude_relative_to q2 if and only if magnitude(q1) NOT =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale.","definition_xrefs":["PATOC:CJM"],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"different_in_magnitude_relative_to","termid":"_global:different_in_magnitude_relative_to"}


id: GO:0036205
data:
  {"annotated_genes":["SJAG_03387","SJAG_01670"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[72880,87138],"is_not":false,"summary":null,"term":"GO:0036205"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of a histone protein by individual cells.","definition_xrefs":["GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein catabolic process","termid":"GO:0030163"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01670":null,"SJAG_03387":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0030163"}],"interesting_parent_ids":["GO:0008150","GO:0030163"],"is_obsolete":false,"name":"histone catabolic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"histone protein catabolic process","type":"exact"}],"termid":"GO:0036205","terms_by_termid":{"GO:0036205":null}}


id: GO:1904500
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of chromatin-mediated maintenance of transcription.","definition_xrefs":["GO_REF:0000058","GOC:BHF","GOC:TermGenie","PMID:22723415","GOC:nc","GOC:BHF_telomere"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of chromatin-mediated maintenance of transcription (obsolete GO:1904500)","synonyms":[{"name":"down regulation of chromatin-mediated maintenance of transcription","type":"exact"},{"name":"down-regulation of chromatin-mediated maintenance of transcription","type":"exact"},{"name":"downregulation of chromatin-mediated maintenance of transcription","type":"exact"},{"name":"inhibition of chromatin-mediated maintenance of transcription","type":"narrow"}],"termid":"GO:1904500"}


id: PBO:0086204
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein that associates with mitochondrial ribosome; SWAT-GFP and mCherry fusion proteins localize to the mitochondria; involved in maintenance of telomere length","termid":"PBO:0086204"}


id: PR:Q9US51
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mtf1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9US51"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial transcription factor 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1002.08c","synonyms":[{"name":"Spom972h-mtf1","type":"exact"}],"termid":"PR:Q9US51"}


id: PBO:0066069
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RARB antisense RNA 1","termid":"PBO:0066069"}


id: FYPO:0000659
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which DNA binding by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal DNA binding","termid":"FYPO:0000656"},{"relation_name":"is_a","term_name":"abolished molecular function","termid":"FYPO:0005446"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000653"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000652"}],"interesting_parent_ids":["FYPO:0000653","FYPO:0001985","FYPO:0000652","FYPO:0000707"],"is_obsolete":false,"name":"abolished DNA binding","synonyms":[{"name":"DNA binding abolished","type":"exact"}],"termid":"FYPO:0000659"}


id: GO:0034349
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system.","definition_xrefs":["GOC:mtg_apoptosis","GOC:sart","CL:0000125"],"direct_ancestors":[{"relation_name":"is_a","term_name":"apoptotic process","termid":"GO:0006915"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"glial cell apoptotic process","synonyms":[{"name":"apoptosis of glia","type":"exact"},{"name":"apoptosis of glial cells","type":"exact"},{"name":"glia apoptosis","type":"exact"},{"name":"glia programmed cell death by apoptosis","type":"exact"},{"name":"glial cell apoptosis","type":"narrow"},{"name":"glial cell programmed cell death by apoptosis","type":"exact"},{"name":"programmed cell death of glia by apoptosis","type":"exact"},{"name":"programmed cell death of glial cells by apoptosis","type":"exact"},{"name":"programmed cell death, glia","type":"exact"},{"name":"programmed cell death, glial cells","type":"exact"}],"termid":"GO:0034349"}


id: PBO:0061575
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"neurotrophin 6 gamma (pseudogene)","termid":"PBO:0061575"}


id: PBO:0082737
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of the Rpd3S histone deacetylase complex; Esa1p-associated factor, nonessential component of the NuA4 acetyltransferase complex, homologous to Drosophila dosage compensation protein MSL3; plays a role in regulating Ty1 transposition","termid":"PBO:0082737"}


id: MONDO:0017526
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"polydactyly of a triphalangeal thumb","termid":"MONDO:0008270"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"polydactyly of a triphalangeal thumb, bilateral","secondary_identifiers":["icd11.foundation:866920497","Orphanet:295150"],"synonyms":[{"name":"bilateral PPD2","type":"exact"},{"name":"preaxial polydactyly type 2, bilateral","type":"exact"}],"termid":"MONDO:0017526","xrefs":{"Monarch":{"xref_id":"0017526"}}}


id: GO:0006303
data:
  {"annotated_genes":["SJAG_03048","SJAG_00640","SJAG_05372","SJAG_04199","SJAG_01677","SJAG_00441","SJAG_04372","SJAG_02527","SJAG_02237","SJAG_01076","SJAG_16460","SJAG_00823","SJAG_05373"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[87999,88626,99456,104578,110526,111310,113882,116405],"is_not":false,"summary":null,"term":"GO:0006303"},{"annotations":[115927,113485],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0097680"},{"annotations":[95372],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0061674"},{"annotations":[101892],"is_not":false,"rel_names":["negatively_regulates","regulates"],"summary":null,"term":"GO:2001033"},{"annotations":[106962],"is_not":false,"rel_names":["positively_regulates","regulates"],"summary":null,"term":"GO:2001034"}]},"cv_name":"biological_process","definition":"The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear.","definition_xrefs":["GOC:rph","PMID:10827453","PMID:24837021"],"direct_ancestors":[{"relation_name":"is_a","term_name":"double-strand break repair","termid":"GO:0006302"}],"gene_count":13,"genes_by_uniquename":{"SJAG_00441":null,"SJAG_00640":null,"SJAG_00823":null,"SJAG_01076":null,"SJAG_01677":null,"SJAG_02237":null,"SJAG_02527":null,"SJAG_03048":null,"SJAG_04199":null,"SJAG_04372":null,"SJAG_05372":null,"SJAG_05373":null,"SJAG_16460":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006259"},{"rel_name":"is_a","termid":"GO:0006281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006259","GO:0006281","GO:0008150"],"is_obsolete":false,"name":"double-strand break repair via nonhomologous end joining","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-5693571"],"synonyms":[{"name":"NHEJ","type":"exact"}],"termid":"GO:0006303","terms_by_termid":{"GO:0006303":null,"GO:0061674":null,"GO:0097680":null,"GO:2001033":null,"GO:2001034":null}}


id: PBO:0083659
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Endonuclease that cleaves pre-rRNA at site A2 for 18S rRNA biogenesis; subunit of U3-containing 90S preribosome processome complex involved in small ribosomal subunit assembly; stimulates Bms1p GTPase and U3 binding activity; similar to RNA cyclase-like proteins but no cyclase activity detected","termid":"PBO:0083659"}


id: GO:0016250
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate.","definition_xrefs":["EC:3.10.1.1"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, acting on acid sulfur-nitrogen bonds","termid":"GO:0016826"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"}],"interesting_parent_ids":["GO:0016787","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"N-sulfoglucosamine sulfohydrolase activity","secondary_identifiers":["Reactome:R-HSA-2090043","MetaCyc:N-SULFOGLUCOSAMINE-SULFOHYDROLASE-RXN","Reactome:R-HSA-1678708","Reactome:R-HSA-9036050","RHEA:17881","Reactome:R-HSA-2263444"],"synonyms":[{"name":"2-desoxy-D-glucoside-2-sulphamate sulphohydrolase (sulphamate sulphohydrolase)","type":"related"},{"name":"N-sulfo-D-glucosamine sulfohydrolase activity","type":"related"},{"name":"N-sulphoglucosamine sulphohydrolase activity","type":"exact"},{"name":"heparin sulfamidase activity","type":"related"},{"name":"sulfoglucosamine sulfamidase activity","type":"related"},{"name":"sulphamidase activity","type":"related"}],"termid":"GO:0016250"}


id: GO:0010947
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination.","definition_xrefs":["GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of meiotic joint molecule formation","termid":"GO:0010946"},{"relation_name":"is_a","term_name":"negative regulation of cell cycle process","termid":"GO:0010948"},{"relation_name":"is_a","term_name":"negative regulation of reproductive process","termid":"GO:2000242"},{"relation_name":"negatively_regulates","term_name":"meiotic joint molecule formation","termid":"GO:0000709"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0007049","GO:0008150"],"is_obsolete":false,"name":"negative regulation of meiotic joint molecule formation","termid":"GO:0010947"}


id: _global:coincident_with
data:
  {"annotation_feature_type":"gene","cv_name":"external","definition":"A relation that holds between two linear structures that are approximately parallel to each other for their entire length and where either the two structures are adjacent to each other or one is part of the other.","direct_ancestors":[{"relation_name":"is_a","term_name":"go_annotation_extension_relation","termid":"_global:go_annotation_extension_relation"},{"relation_name":"is_a","term_name":"mereotopologically_related_to","termid":"_global:mereotopologically_related_to"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coincident_with","secondary_identifiers":["RO:0002008"],"termid":"_global:coincident_with"}


id: FYPO:0006040
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubules attached to the kinetochore lengthen instead of shortening during mitotic metaphase chromosome recapture.","definition_xrefs":["PMID:27146110","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal microtubule polymerization during vegetative growth","termid":"FYPO:0004614"},{"relation_name":"is_a","term_name":"abnormal mitotic metaphase chromosome recapture","termid":"FYPO:0005362"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000641"},{"rel_name":"is_a","termid":"FYPO:0000054"},{"rel_name":"part_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000337"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"part_of","termid":"FYPO:0000631"},{"rel_name":"part_of","termid":"FYPO:0001320"},{"rel_name":"part_of","termid":"FYPO:0005447"},{"rel_name":"part_of","termid":"FYPO:0000641"},{"rel_name":"part_of","termid":"FYPO:0000337"}],"interesting_parent_ids":["FYPO:0000337","FYPO:0000002","FYPO:0000054","FYPO:0000138","FYPO:0000641","FYPO:0000631","FYPO:0005447","FYPO:0001985","FYPO:0001320"],"is_obsolete":false,"name":"abnormal kinetochore microtubule polymerization during mitotic metaphase chromosome recapture","synonyms":[{"name":"abnormal kinetochore microtubule polymerization during chromosome recapture during mitosis","type":"exact"},{"name":"abnormal kinetochore microtubule polymerization during chromosome recapture during mitotic metaphase","type":"exact"},{"name":"abnormal kinetochore microtubule polymerization during kinetochore retrieval in mitotic metaphase","type":"exact"},{"name":"abnormal kinetochore microtubule polymerization during metaphase chromosome retrieval to the spindle pole body","type":"exact"},{"name":"abnormal kinetochore microtubule polymerization during mitotic metaphase chromosome recapture during vegetative growth","type":"exact"},{"name":"abnormal kinetochore microtubule polymerization during mitotic metaphase kinetochore retrieval","type":"exact"},{"name":"abnormal kinetochore microtubule polymerization during sister kinetochore recapture","type":"exact"}],"termid":"FYPO:0006040"}


id: PBO:0001407
data:
  {"annotation_feature_type":"gene","cv_name":"misc","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"overlapping genome wide occupancy in promoters Nap1/Hrp1/Hrp3","termid":"PBO:0001407"}


id: GO:0030612
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: arsenate + [thioredoxin]-dithiol + H+ = arsenite + [thioredoxin]-disulfide + H2O.","definition_xrefs":["RHEA:43848"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor","termid":"GO:0030614"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"arsenate reductase (thioredoxin) activity","secondary_identifiers":["EC:1.20.4.4","MetaCyc:RXN-10737"],"termid":"GO:0030612"}


id: GO:0007143
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline.","definition_xrefs":["GOC:ems","GOC:vw","GOC:mah","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"meiotic nuclear division","termid":"GO:0140013"},{"relation_name":"part_of","term_name":"female gamete generation","termid":"GO:0007292"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0140013"},{"rel_name":"part_of","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0008150","GO:0007049","GO:0140013"],"is_obsolete":false,"name":"female meiotic nuclear division","synonyms":[{"name":"female meiosis","type":"broad"},{"name":"female meiotic division","type":"broad"}],"termid":"GO:0007143"}


id: GO:0044618
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. OBSOLETE. The process in which an organism effects a change in the relaxation of smooth muscle in the uterus of a second organism.","definition_xrefs":["GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete obsolete modulation of relaxation of uterine smooth muscle in another organism (obsolete GO:0044618)","synonyms":[{"name":"modulation of relaxation of uterine smooth muscle in other organism","type":"exact"},{"name":"regulation of relaxation of uterine smooth muscle in other organism","type":"exact"}],"termid":"GO:0044618"}


id: MONDO:1012428
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"complement component 4 deficiency, non-human animal","termid":"MONDO:1011730"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"complement component 4 deficiency, domestic guinea pig","secondary_identifiers":["OMIA:001626-10141"],"synonyms":[{"name":"C4 deficiency, domestic guinea pig","type":"exact"}],"termid":"MONDO:1012428","xrefs":{"Monarch":{"xref_id":"1012428"}}}


id: PBO:0001644
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"oligosaccharyltransferase subunit Ost4 (predicted)","termid":"PBO:0001644"}


id: PBO:0076881
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"testis expressed 30","termid":"PBO:0076881"}


id: PBO:0027498
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_MTT","termid":"PBO:0027498"}


id: PBO:0057723
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 1302-8","termid":"PBO:0057723"}


id: GO:0031981
data:
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id: FYECO:0000303
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which menadione was added to the medium or assay buffer in excess compared to standard medium or assay buffers.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping excess","termid":"FYECO:0000109"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ menadione","termid":"FYECO:0000303"}


id: PBO:0078159
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T cell receptor alpha variable 37 (pseudogene)","termid":"PBO:0078159"}


id: GO:0007252
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process of introducing a phosphate group into an inhibitor of kappa B (I-kappaB) protein. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing bound NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.","definition_xrefs":["PMID:7594468","PMID:21772278","GOC:jl","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein phosphorylation","termid":"GO:0006468"},{"relation_name":"part_of","term_name":"canonical NF-kappaB signal transduction","termid":"GO:0007249"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"I-kappaB phosphorylation","synonyms":[{"name":"IKB phosphorylation","type":"exact"},{"name":"IkappaB phosphorylation","type":"exact"},{"name":"inhibitor of NF-kappaB phosphorylation","type":"exact"},{"name":"inhibitor of kappaB phosphorylation","type":"exact"}],"termid":"GO:0007252"}


id: MOD:01523
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"The protein modification reporter fragment produced by an Applied Biosystems iTRAQ4plex 115 reagent derivatized residue.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"derives_from","term_name":"iTRAQ4plex-115 reporter+balance reagent acylated residue","termid":"MOD:01492"},{"relation_name":"is_a","term_name":"iTRAQ4plex reporter fragment","termid":"MOD:01521"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"iTRAQ4plex-115 reporter fragment","synonyms":[{"name":"4-methyl-1-methylidenepiperazin-1-ium","type":"exact"}],"termid":"MOD:01523"}


id: MONDO:0001741
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hyperfunction of the parathyroid glands resulting in the overproduction of parathyroid hormone. It may be primary or secondary; primary hyperparathyroidism is caused by parathyroid adenoma, parathyroid hyperplasia, parathyroid carcinoma, and multiple endocrine neoplasia. It is associated with hypercalcemia and hypophosphatemia. Signs and symptoms include weakness, fatigue, nausea, vomiting, constipation, depression, bone pain, osteoporosis, cystic bone lesions, and kidney stones. Secondary hyperparathyroidism is caused by the chronic stimulation of the parathyroid glands in patients with chronic renal failure, rickets, and malabsorption syndromes.","definition_xrefs":["NCIT:C48259"],"direct_ancestors":[{"relation_name":"is_a","term_name":"parathyroid gland disorder","termid":"MONDO:0001223"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hyperparathyroidism","secondary_identifiers":["UMLS:C0020502","icd11.foundation:9633776","SCTID:66999008","EFO:0008506","MEDGEN:6967","MESH:D006961","ICD9:252.0","NANDO:2200343","ICD9:252.00","DOID:13543","NANDO:2100123"],"synonyms":[{"name":"hyperparathyroidism","type":"exact"}],"termid":"MONDO:0001741","xrefs":{"Monarch":{"xref_id":"0001741"}}}


id: PBO:0082715
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of the NuA3b histone acetyltransferase complex; regulates interaction between NuA3b and H3K36me3 at the transcribed regions of genes; contains PWWP domain; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO); protein abundance increases in response to DNA replication stress; relocalizes to the cytosol in response to hypoxia","termid":"PBO:0082715"}


id: PBO:0085398
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Plasma membrane protein; involved in G-protein mediated pheromone signaling pathway; overproduction suppresses bem1 mutations; MDG1 has a paralog, CRP1, that arose from the whole genome duplication","termid":"PBO:0085398"}


id: GO:0008782
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenine + S-D-ribosyl-L-homocysteine.","definition_xrefs":["EC:3.2.2.9"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, hydrolyzing N-glycosyl compounds","termid":"GO:0016799"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016798"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016798","GO:0016787","GO:0003674"],"is_obsolete":false,"name":"adenosylhomocysteine nucleosidase activity","secondary_identifiers":["RHEA:17805","MetaCyc:ADENOSYLHOMOCYSTEINE-NUCLEOSIDASE-RXN"],"synonyms":[{"name":"5'-methyladenosine nucleosidase activity","type":"related"},{"name":"AdoHcy/MTA nucleosidase activity","type":"related"},{"name":"S-adenosyl-L-homocysteine homocysteinylribohydrolase activity","type":"related"},{"name":"S-adenosylhomocysteine hydrolase activity","type":"broad"},{"name":"S-adenosylhomocysteine nucleosidase activity","type":"related"},{"name":"S-adenosylhomocysteine/5'-methylthioadenosine nucleosidase activity","type":"related"}],"termid":"GO:0008782"}


id: PBO:0026947
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_transcription_during_meiotic_cell_cycle","termid":"PBO:0026947"}


id: FYPO:0002678
data:
  {"alleles_by_uniquename":{"SJAG_00610:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_00610","name":"pck2delta","uniquename":"SJAG_00610:allele-1"},"SJAG_04551:allele-4":{"allele_type":"partial_amino_acid_deletion","description":"Pmk1 from S. pombe with deleted residues 82-105","gene_uniquename":"SJAG_04551","name":"Pmk1Sp(delta82-105)","uniquename":"SJAG_04551:allele-4"}},"annotation_feature_type":"genotype","cv_annotations":{"single_locus_phenotype":[{"annotations":[118876,118884],"is_not":false,"summary":null,"term":"FYPO:0002678"},{"annotations":[118883],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0002033"}]},"cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein phosphorylation","termid":"FYPO:0002677"},{"relation_name":"is_a","term_name":"abolished cellular process","termid":"FYPO:0005449"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00610":null,"SJAG_04551":null},"genotype_count":2,"genotypes_by_uniquename":{"Pmk1Sp(delta82-105)-Pmk1_from_S._pombe_with_deleted_residues_82-105-partial_amino_acid_deletion-expression-not_assayed_or_wild_type":{"display_name":"Pmk1Sp(delta82-105)(Pmk1 from S. pombe with deleted residues 82-105 Δaa)","display_uniquename":"Pmk1Sp(delta82-105)-Pmk1_from_S._pombe_with_deleted_residues_82-105-partial_amino_acid_deletion-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04551:allele-4","expression":"Not assayed or wild type"}]}]},"pck2delta":{"display_name":"pck2delta","display_uniquename":"pck2delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_00610:allele-1","expression":"Null"}]}]}},"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0002274"}],"interesting_parent_ids":["FYPO:0002274","FYPO:0001985","FYPO:0002494","FYPO:0000002","FYPO:0005447"],"is_obsolete":false,"name":"abolished protein phosphorylation","references_by_uniquename":{"PMID:34198697":null},"single_locus_annotated_genes":["SJAG_04551","SJAG_00610"],"single_locus_genotype_uniquenames":["Pmk1Sp(delta82-105)-Pmk1_from_S._pombe_with_deleted_residues_82-105-partial_amino_acid_deletion-expression-not_assayed_or_wild_type","pck2delta"],"synonyms":[{"name":"protein phosphorylation abolished","type":"exact"}],"termid":"FYPO:0002678","terms_by_termid":{"FYECO:0000207":null,"FYPO:0002033":null,"FYPO:0002678":null}}


