# terms

id: GO:0036174
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: butane + O2 + NAD(P)H + H+ = butanol + NAD(P)+ + H2O.","definition_xrefs":["PMID:19383682","GOC:dh","PMID:17526838"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen","termid":"GO:0016713"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"butane monooxygenase activity","synonyms":[{"name":"sBMO","type":"related"},{"name":"soluble butane monooxygenase","type":"related"}],"termid":"GO:0036174"}


id: PBO:0067664
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 842, pseudogene","termid":"PBO:0067664"}


id: GO:0070634
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of ammonium ions from one side of an epithelium to the other.","definition_xrefs":["GOC:mah","GOC:yaf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transepithelial transport","termid":"GO:0070633"},{"relation_name":"is_a","term_name":"nitrogen compound transport","termid":"GO:0071705"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810","GO:0051179"],"is_obsolete":false,"name":"transepithelial ammonium transport","termid":"GO:0070634"}


id: PBO:0045201
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DnaJ heat shock protein family (Hsp40) member B12","termid":"PBO:0045201"}


id: MOD:01929
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively crosslinks an either an L-asparagine residue or an L-aspartic acid residue with an L-lysine residue by an isopeptide bond with the formation of N6-(L-isoaspartyl)-L-lysine.","definition_xrefs":["PubMed:11000116","DeltaMass:0","RESID:AA0294","ChEBI:21862","PubMed:6503713"],"direct_ancestors":[{"relation_name":"is_a","term_name":"isopeptide crosslinked residues","termid":"MOD:00688"},{"relation_name":"is_a","term_name":"N6-acylated L-lysine","termid":"MOD:01875"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:01875"}],"interesting_parent_ids":["MOD:01875"],"is_obsolete":false,"name":"N6-(L-isoaspartyl)-L-lysine","synonyms":[{"name":"(2S)-2-amino-6-([(3S)-3-amino-3-carboxypropanoyl]amino)hexanoic acid","type":"exact"},{"name":"CROSSLNK Isoaspartyl lysine isopeptide (Lys-Asn)","type":"exact"},{"name":"N(epsilon)-(beta-aspartyl)lysine","type":"exact"},{"name":"N-(beta-Aspartyl)-Lysine (Crosslink)","type":"exact"},{"name":"N6-(L-isoaspartyl)-L-lysine","type":"exact"},{"name":"XLNK-4Asp-N6Lys","type":"exact"},{"name":"beta-(N6-lysyl)aspartyl acid","type":"exact"},{"name":"isoaspartyl N6-lysine","type":"exact"}],"termid":"MOD:01929"}


id: PBO:0081006
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger and BTB domain containing 43","termid":"PBO:0081006"}


id: PBO:0060780
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADH:ubiquinone oxidoreductase subunit B9 pseudogene 2","termid":"PBO:0060780"}


id: GO:0101008
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.","definition_xrefs":["GOC:mec"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of transcription from RNA polymerase II promoter in response to increased salt (obsolete GO:0101008)","termid":"GO:0101008"}


id: PBO:0030932
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_glutamate-ammonia_ligase_activity","termid":"PBO:0030932"}


id: GO:0071928
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals generated as a consequence of tyramine binding to a cell surface receptor.","definition_xrefs":["GOC:mah","PMID:15355245"],"direct_ancestors":[{"relation_name":"is_a","term_name":"octopamine or tyramine signaling pathway","termid":"GO:0007211"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"tyramine signaling pathway","synonyms":[{"name":"tyramine signalling pathway","type":"exact"}],"termid":"GO:0071928"}


id: PR:O13828
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- dcp2 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O13828"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mRNA decapping complex subunit 2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC19A8.12","synonyms":[{"name":"Spom972h-dcp2","type":"exact"}],"termid":"PR:O13828"}


id: MONDO:0023059
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"excluded_subClassOf","term_name":"intellectual disability","termid":"MONDO:0001071"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Elliott ludman Teebi syndrome","secondary_identifiers":["MEDGEN:443982","UMLS:C2931128","MESH:C536204"],"synonyms":[{"name":"multiple congenital anomalies, severe psychomotor retardation and symmetrical circumferential skin creases of arms and legs","type":"related"}],"termid":"MONDO:0023059","xrefs":{"Monarch":{"xref_id":"0023059"}}}


id: PBO:0070179
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U7 small nuclear 94 pseudogene","termid":"PBO:0070179"}


id: GO:0018981
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways involving triethanolamine, a combustible, hygroscopic, colorless liquid commonly used in dry-cleaning solutions, cosmetics, detergents, textile processing, wool scouring, and as a corrosion inhibitor and pharmaceutical alkalizing agent.","definition_xrefs":["GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete triethanolamine metabolic process (obsolete GO:0018981)","synonyms":[{"name":"triethanolamine metabolism","type":"exact"}],"termid":"GO:0018981"}


id: GO:0072181
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The developmental process pertaining to the initial formation of a mesonephric duct. A mesonephric duct is a tube that drains the mesonephros.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mesonephric tubule formation","termid":"GO:0072172"},{"relation_name":"is_a","term_name":"nephric duct formation","termid":"GO:0072179"},{"relation_name":"is_a","term_name":"mesonephric duct morphogenesis","termid":"GO:0072180"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mesonephric duct formation","synonyms":[{"name":"Wolffian duct formation","type":"exact"}],"termid":"GO:0072181"}


id: PBO:0089937
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WW domain protein Wwm1","termid":"PBO:0089937"}


id: FYPO:0000908
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"OBSOLETE. A mixed population phenotype in which some cells in a population are viable and others are inviable.","definition_xrefs":["PomBase:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete mixed population including viable and inviable cells (obsolete FYPO:0000908)","termid":"FYPO:0000908"}


id: FYPO:0000688
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity is decreased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity","termid":"FYPO:0000687"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000652"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000652","FYPO:0000654","FYPO:0000707","FYPO:0000661"],"is_obsolete":false,"name":"decreased peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity","synonyms":[{"name":"reduced peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity","type":"exact"}],"termid":"FYPO:0000688"}


id: MONDO:0800175
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare, cardiac condition characterized by severely decreased cardiac output, hypoperfusion and end-organ dysfunction, in the presence of adequate intravascular volume. The clinical presentation is variable and may range from subtle hemodynamic alterations to overt cardiovascular collapse. Commonly reported features include dyspnea, crackles, elevated jugular venous pressure, altered mental state, abnormal pulse pressure, oliguria, cold extremities, and increased serum lactate levels.","definition_xrefs":["Orphanet:97292"],"direct_ancestors":[{"relation_name":"is_a","term_name":"heart disorder","termid":"MONDO:0005267"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"cardiogenic shock","secondary_identifiers":["GARD:19362","MEDGEN:48650","icd11.foundation:1974956233","UMLS:C0036980","ICD10CM:R57.0","MedDRA:10007625"],"termid":"MONDO:0800175","xrefs":{"Monarch":{"xref_id":"0800175"}}}


id: GO:0052629
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate + 2 H+.","definition_xrefs":["PMID:19901554","RHEA:39019"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphatidylinositol-3,5-bisphosphate phosphatase activity","termid":"GO:0106018"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016787","GO:0003824","GO:0016788"],"is_obsolete":false,"name":"phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity","secondary_identifiers":["Reactome:R-HSA-6809778","Reactome:R-HSA-1676105","Reactome:R-HSA-1676065","MetaCyc:RXN-10958","Reactome:R-HSA-6809320","Reactome:R-HSA-1676203","Reactome:R-HSA-6809944","EC:3.1.3.95"],"termid":"GO:0052629"}


id: PBO:0039080
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"alkylglycerone phosphate synthase","termid":"PBO:0039080"}


id: GO:0042951
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of arbutin, a glycoside found in the bearberry and related plants which has been used to treat urinary-tract diseases, from one side of a membrane to the other.","definition_xrefs":["GOC:mtg_transport","GOC:jl","PMID:19965875"],"direct_ancestors":[{"relation_name":"is_a","term_name":"beta-glucoside transmembrane transporter activity","termid":"GO:0015573"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0022857","GO:0003674","GO:0005215"],"is_obsolete":false,"name":"arbutin transmembrane transporter activity","termid":"GO:0042951"}


id: GO:0008726
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: an alkanesulfonate + O2 + FMNH2 = an aldehyde + sulfite + H2O + FMN.","definition_xrefs":["MetaCyc:RXN0-280"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen","termid":"GO:0016712"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"alkanesulfonate monooxygenase activity","secondary_identifiers":["EC:1.14.14.5","RHEA:23064"],"synonyms":[{"name":"FMNH(2)-dependent aliphatic sulfonate monooxygenase activity","type":"related"},{"name":"FMNH(2)-dependent alkanesulfonate monooxygenase activity","type":"exact"},{"name":"FMNH2-dependent aliphatic sulfonate monooxygenase activity","type":"related"},{"name":"SsuD","type":"related"},{"name":"alkanesulfonate, reduced-FMN:oxygen oxidoreductase activity","type":"related"},{"name":"alkanesulphonate monooxygenase activity","type":"exact"},{"name":"sulfate starvation-induced protein 6 activity","type":"related"}],"termid":"GO:0008726"}


id: GO:0060646
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an internal epithelial cell of the mammary gland bud. Internal cells are small and of irregular shape.","definition_xrefs":["PMID:12558599","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epithelial cell differentiation involved in mammary gland bud morphogenesis","termid":"GO:0060643"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"internal mammary gland bud epithelial cell differentiation","termid":"GO:0060646"}


id: GO:1903419
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a protein is transported to, or maintained in, a location within a cortical endoplasmic reticulum.","definition_xrefs":["GO_REF:0000087","GOC:TermGenie","PMID:25103238"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein localization to cell cortex","termid":"GO:0072697"},{"relation_name":"is_a","term_name":"protein localization to endoplasmic reticulum tubular network","termid":"GO:1903420"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0051179"],"is_obsolete":false,"name":"protein localization to cortical endoplasmic reticulum","synonyms":[{"name":"protein localisation in cortical endoplasmic reticulum","type":"exact"},{"name":"protein localisation to cortical endoplasmic reticulum","type":"exact"},{"name":"protein localization in cortical endoplasmic reticulum","type":"exact"},{"name":"protein localization to cortical ER","type":"exact"}],"termid":"GO:1903419"}


id: GO:0030279
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of ossification","termid":"GO:0030278"},{"relation_name":"is_a","term_name":"negative regulation of multicellular organismal process","termid":"GO:0051241"},{"relation_name":"negatively_regulates","term_name":"ossification","termid":"GO:0001503"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of ossification","synonyms":[{"name":"down regulation of ossification","type":"exact"},{"name":"down-regulation of ossification","type":"exact"},{"name":"downregulation of ossification","type":"exact"},{"name":"inhibition of ossification","type":"narrow"},{"name":"negative regulation of bone biosynthesis","type":"exact"},{"name":"negative regulation of bone formation","type":"exact"}],"termid":"GO:0030279"}


id: PBO:0060005
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-ND4L pseudogene 25","termid":"PBO:0060005"}


id: MONDO:1010767
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Vitiligo that occurs in horse.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vitiligo, non-human animal","termid":"MONDO:1010136"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vitiligo, horse","secondary_identifiers":["OMIA:001055-9796"],"termid":"MONDO:1010767","xrefs":{"Monarch":{"xref_id":"1010767"}}}


id: PBO:0071908
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RPS3A pseudogene 47","termid":"PBO:0071908"}


id: PBO:0086350
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"P-type ATPase sodium pump; involved in Na+ and Li+ efflux to allow salt tolerance","termid":"PBO:0086350"}


id: PBO:0047892
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fragile site, aphidicolin type, common, fra(6)(q21)","termid":"PBO:0047892"}


id: PBO:0070827
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L13a pseudogene 6","termid":"PBO:0070827"}


id: FYPO:0005244
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing arabinose as the carbon source.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased vegetative cell population growth","termid":"FYPO:0001355"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0002057"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0002057","FYPO:0005447","FYPO:0002060","FYPO:0000139","FYPO:0000003","FYPO:0002058"],"is_obsolete":false,"name":"decreased cell population growth on arabinose carbon source","synonyms":[{"name":"decreased growth on arabinose carbon source","type":"broad"},{"name":"decreased vegetative cell growth on arabinose carbon source","type":"exact"},{"name":"reduced cell growth on arabinose carbon source","type":"related"},{"name":"slow cell growth on arabinose carbon source","type":"narrow"}],"termid":"FYPO:0005244"}


id: MONDO:1012417
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"persistent right aortic arch with subclavian artery and ligamentum arteriosum, non-human animal","termid":"MONDO:1011649"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"persistent right aortic arch with subclavian artery and ligamentum arteriosum, dog","secondary_identifiers":["OMIA:001570-9615"],"termid":"MONDO:1012417","xrefs":{"Monarch":{"xref_id":"1012417"}}}


id: PATO:0001003
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0001003 relative alternation value (obsolete PATO:0001003)","termid":"PATO:0001003"}


id: PBO:0119788
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Sec61 translocon beta subunit, GEF Sbh1","termid":"PBO:0119788"}


id: GO:1902003
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of amyloid-beta formation.","definition_xrefs":["GOC:TermGenie","GOC:dph","PMID:17098871"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of amide metabolic process","termid":"GO:0034248"},{"relation_name":"is_a","term_name":"regulation of amyloid precursor protein catabolic process","termid":"GO:1902991"},{"relation_name":"regulates","term_name":"amyloid-beta formation","termid":"GO:0034205"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of amyloid-beta formation","synonyms":[{"name":"regulation of beta-amyloid formation","type":"exact"}],"termid":"GO:1902003"}


id: GO:2000252
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of feeding behavior.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of behavior","termid":"GO:0048521"},{"relation_name":"is_a","term_name":"regulation of feeding behavior","termid":"GO:0060259"},{"relation_name":"negatively_regulates","term_name":"feeding behavior","termid":"GO:0007631"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of feeding behavior","synonyms":[{"name":"negative regulation of behavioral response to food","type":"exact"},{"name":"negative regulation of behavioural response to food","type":"exact"},{"name":"negative regulation of drinking","type":"related"},{"name":"negative regulation of eating","type":"related"},{"name":"negative regulation of feeding behaviour","type":"exact"}],"termid":"GO:2000252"}


id: PBO:0048375
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"golgi associated RAB2 interactor 1A","termid":"PBO:0048375"}


id: MONDO:0005906
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An abscess that develops in the space surrounding one or both palatine tonsils.","definition_xrefs":["NCIT:C128322"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bacterial infectious disease","termid":"MONDO:0005113"},{"relation_name":"is_a","term_name":"abscess","termid":"MONDO:0005227"},{"relation_name":"is_a","term_name":"disorder of pharynx","termid":"MONDO:0020592"},{"relation_name":"is_a","term_name":"lymphoid system disorder","termid":"MONDO:0044986"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"peritonsillar abscess","secondary_identifiers":["UMLS:C0031157","ICD10CM:J36","icd11.foundation:1782446047","ICD9:475","MEDGEN:45819","MESH:D000039","SCTID:15033003","EFO:0007429"],"synonyms":[{"name":"quinsy","type":"exact"}],"termid":"MONDO:0005906","xrefs":{"Monarch":{"xref_id":"0005906"}}}


id: MONDO:0015711
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete specific antibody deficiency with normal immunoglobulin concentrations and normal numbers of B cells (obsolete MONDO:0015711)","secondary_identifiers":["NANDO:2200721","NANDO:1200348","Orphanet:169443","icd11.foundation:29897844"],"termid":"MONDO:0015711","xrefs":{"Monarch":{"xref_id":"0015711"}}}


id: PBO:0030964
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_histone_H3-K9_trimethylation_at_centromere_inner_repeat","termid":"PBO:0030964"}


id: GO:0060342
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The membrane surrounding the inner segment of a vertebrate photoreceptor. The photoreceptor inner segment contains mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plasma membrane region","termid":"GO:0098590"},{"relation_name":"part_of","term_name":"photoreceptor inner segment","termid":"GO:0001917"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005886"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0005886"],"is_obsolete":false,"name":"photoreceptor inner segment membrane","termid":"GO:0060342"}


id: PATO:0000599
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A width which is relatively small.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"decreased_in_magnitude_relative_to","term_name":"normal","termid":"PATO:0000461"},{"relation_name":"is_a","term_name":"decreased size","termid":"PATO:0000587"},{"relation_name":"is_a","term_name":"width","termid":"PATO:0000921"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"decreased width","synonyms":[{"name":"narrow","type":"related"}],"termid":"PATO:0000599"}


id: GO:0030917
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages.","definition_xrefs":["GOC:dgh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure development","termid":"GO:0048856"},{"relation_name":"part_of","term_name":"brain development","termid":"GO:0007420"},{"relation_name":"part_of","term_name":"rostrocaudal neural tube patterning","termid":"GO:0021903"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"midbrain-hindbrain boundary development","synonyms":[{"name":"MHB development","type":"exact"},{"name":"isthmic organizer development","type":"exact"},{"name":"isthmomesencephalic boundary development","type":"exact"},{"name":"isthmus development","type":"exact"},{"name":"midbrain-hindbrain orgainizer development","type":"exact"}],"termid":"GO:0030917"}


id: PBO:0063908
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha","termid":"PBO:0063908"}


id: GO:0015400
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Enables the transfer of ammonium from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.","definition_xrefs":["GOC:mtg_transport","ISBN:0815340729"],"gene_count":0,"genotype_count":0,"name":"obsolete low-affinity secondary active ammonium transmembrane transporter activity (obsolete GO:0015400)","synonyms":[{"name":"low affinity ammonium transmembrane transporter activity","type":"related"},{"name":"low affinity secondary active ammonium transmembrane transporter activity","type":"exact"}],"termid":"GO:0015400"}


id: PBO:0050075
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"5-hydroxymethylcytosine binding, ES cell specific","termid":"PBO:0050075"}


id: MONDO:0005925
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Bovine respiratory disease found in animals that have been shipped or exposed to cattle recently transported. The major agent responsible for the disease is mannheimia haemolytica and less commonly, pasteurella multocida or haemophilus somnus. All three agents are normal inhabitants of the bovine nasal pharyngeal mucosa but not the lung. They are considered opportunistic pathogens following stress, physiological and/or a viral infection. The resulting bacterial fibrinous bronchopneumonia is often fatal.","definition_xrefs":["MESH:D012766"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bacterial infectious disease","termid":"MONDO:0005113"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pneumonic pasteurellosis","secondary_identifiers":["EFO:0007449","MEDGEN:11408","UMLS:C0036969"],"termid":"MONDO:0005925","xrefs":{"Monarch":{"xref_id":"0005925"}}}


id: MONDO:0005642
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Conjunctivitis due to hypersensitivity to various allergens.","definition_xrefs":["MESH:D003233"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chronic conjunctivitis","termid":"MONDO:0002314"},{"relation_name":"is_a","term_name":"eye allergy","termid":"MONDO:0005551"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328","MONDO:0005046"],"is_obsolete":false,"name":"atopic conjunctivitis","secondary_identifiers":["MEDGEN:3590","EFO:0007141","NCIT:C34506","UMLS:C0009766","HP:0007879","ICD9:372.14","SCTID:473460002","DOID:11204"],"synonyms":[{"name":"Atopic conjunctivitis","type":"exact"},{"name":"allergic conjunctivitis","type":"exact"},{"name":"allergic conjunctivitis (disease)","type":"exact"},{"name":"allergic form of conjunctivitis (disease)","type":"exact"}],"termid":"MONDO:0005642","xrefs":{"Monarch":{"xref_id":"0005642"}}}


id: PBO:0003787
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nucleolar protein Nop52 family (predicted)","termid":"PBO:0003787"}


id: MONDO:0004988
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A carcinoma that arises from glandular epithelial cells of the breast","direct_ancestors":[{"relation_name":"is_a","term_name":"integumentary system cancer","termid":"MONDO:0000653"},{"relation_name":"is_a","term_name":"adenocarcinoma","termid":"MONDO:0004970"},{"relation_name":"is_a","term_name":"breast carcinoma","termid":"MONDO:0004989"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"breast adenocarcinoma","secondary_identifiers":["EFO:0000304","NCIT:C5214","MEDGEN:167809","UMLS:C0858252","DOID:3458"],"synonyms":[{"name":"adenocarcinoma of breast","type":"exact"},{"name":"adenocarcinoma of the breast","type":"exact"},{"name":"breast adenocarcinoma","type":"exact"},{"name":"mammary adenocarcinoma","type":"exact"}],"termid":"MONDO:0004988","xrefs":{"Monarch":{"xref_id":"0004988"}}}


id: PBO:0060790
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADH:ubiquinone oxidoreductase core subunit S1","termid":"PBO:0060790"}


id: GO:0035183
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A proteinaceous actin-rich layer of the insect ovarian ring canal that forms subcortically to the outer rim. The electron dense inner rim accumulates after the final mitotic division of each germline syncytia, and contains actin, a phosphotyrosine protein, and a number of cytoskeletal proteins.","definition_xrefs":["PMID:10556087","PMID:7925006","PMID:9093858"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"extracellular region","termid":"GO:0005576"},{"relation_name":"part_of","term_name":"female germline ring canal","termid":"GO:0035324"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005576"}],"interesting_parent_ids":["GO:0005576","GO:0005575"],"is_obsolete":false,"name":"female germline ring canal inner rim","synonyms":[{"name":"germline ring canal inner rim","type":"broad"},{"name":"nurse cell ring canal inner rim","type":"narrow"},{"name":"ovarian ring canal inner rim","type":"narrow"}],"termid":"GO:0035183"}


id: MOD:00043
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-cysteine residue to S-phospho-L-cysteine.","definition_xrefs":["PubMed:7961745","PubMed:8128219","PubMed:3142516","RESID:AA0034","Unimod:21#C"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphorylated residue","termid":"MOD:00696"},{"relation_name":"is_a","term_name":"residues isobaric at 182.96-182.98 Da","termid":"MOD:00777"},{"relation_name":"is_a","term_name":"modified L-cysteine residue","termid":"MOD:00905"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"},{"rel_name":"is_a","termid":"MOD:00696"}],"interesting_parent_ids":["MOD:00696","MOD:00905"],"is_obsolete":false,"name":"S-phospho-L-cysteine","synonyms":[{"name":"(2R)-2-amino-3-(phosphonosulfanyl)propanoic acid","type":"exact"},{"name":"2-azanyl-3-(phosphonosulfanyl)propanoic acid","type":"exact"},{"name":"ACT_SITE Phosphocysteine intermediate","type":"exact"},{"name":"MOD_RES Phosphocysteine","type":"exact"},{"name":"PCys","type":"exact"},{"name":"Phospho","type":"related"},{"name":"Phosphorylation","type":"related"},{"name":"S-phospho-L-cysteine","type":"exact"},{"name":"S-phosphonocysteine","type":"exact"},{"name":"S-phosphorylated L-cysteine","type":"exact"},{"name":"S3-phosphocysteine","type":"exact"},{"name":"cysteine phosphate thioester","type":"exact"}],"termid":"MOD:00043"}


id: PBO:0016975
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Schizosaccharomyces specific protein Mug95","termid":"PBO:0016975"}


id: PBO:0047012
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 90 member A15, pseudogene","termid":"PBO:0047012"}


id: GO:1903854
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of stress response to copper ion.","definition_xrefs":["GOC:TermGenie","GOC:kmv","PMID:23437011","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of response to stimulus","termid":"GO:0048585"},{"relation_name":"is_a","term_name":"regulation of stress response to copper ion","termid":"GO:1903853"},{"relation_name":"negatively_regulates","term_name":"stress response to copper ion","termid":"GO:1990169"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of stress response to copper ion","synonyms":[{"name":"down regulation of response to copper ion stress","type":"exact"},{"name":"down regulation of response to copper toxicity","type":"related"},{"name":"down regulation of stress response to copper ion","type":"exact"},{"name":"down-regulation of response to copper ion stress","type":"exact"},{"name":"down-regulation of response to copper toxicity","type":"related"},{"name":"down-regulation of stress response to copper ion","type":"exact"},{"name":"downregulation of response to copper ion stress","type":"exact"},{"name":"downregulation of response to copper toxicity","type":"related"},{"name":"downregulation of stress response to copper ion","type":"exact"},{"name":"inhibition of response to copper ion stress","type":"narrow"},{"name":"inhibition of response to copper toxicity","type":"related"},{"name":"inhibition of stress response to copper ion","type":"narrow"},{"name":"negative regulation of response to copper ion stress","type":"exact"},{"name":"negative regulation of response to copper toxicity","type":"related"}],"termid":"GO:1903854"}


id: MONDO:1011361
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Thymus gland disorder that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"immune system disorder, non-human animal","termid":"MONDO:0700106"},{"relation_name":"is_a","term_name":"endocrine system disorder, non-human animal","termid":"MONDO:1011317"},{"relation_name":"is_a","term_name":"hematologic disorder, non-human animal","termid":"MONDO:1011319"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"thymus gland disorder, non-human animal","termid":"MONDO:1011361","xrefs":{"Monarch":{"xref_id":"1011361"}}}


id: GO:0106413
data:
  {"annotated_genes":["SJAG_03236","SJAG_00174","SJAG_01041","SJAG_03240"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[104233,88921,109203,118049],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0106414"},{"annotations":[109204],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0102262"},{"annotations":[109205],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0102263"},{"annotations":[104234],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0102264"},{"annotations":[61141],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0102266"},{"annotations":[61142],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0102267"},{"annotations":[67193],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0102265"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: RNA-uracil + NAD(P)+ = RNA-dihydrouridine + NAD(P)H + H+.","definition_xrefs":["PMID:25073379","PMID:12581659"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor","termid":"GO:0016628"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00174":null,"SJAG_01041":null,"SJAG_03236":null,"SJAG_03240":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"RNA dihydrouridine synthase activity","references_by_uniquename":{"GO_REF:0000003":null,"GO_REF:0000107":null,"GO_REF:0000117":null},"termid":"GO:0106413","terms_by_termid":{"GO:0102262":null,"GO:0102263":null,"GO:0102264":null,"GO:0102265":null,"GO:0102266":null,"GO:0102267":null,"GO:0106414":null}}


id: PBO:0073007
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sodium voltage-gated channel alpha subunit 7","termid":"PBO:0073007"}


id: GO:1905355
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The aggregation, arrangement and bonding together of a set of components to form a spine apparatus.","definition_xrefs":["GOC:bf","GO_REF:0000079","GOC:TermGenie","GOC:PARL","PMID:12928494"],"direct_ancestors":[{"relation_name":"is_a","term_name":"organelle assembly","termid":"GO:0070925"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0044085","GO:0008150"],"is_obsolete":false,"name":"spine apparatus assembly","synonyms":[{"name":"dense material assembly","type":"narrow"},{"name":"dense material formation","type":"narrow"},{"name":"spine apparatus formation","type":"exact"}],"termid":"GO:1905355"}


id: PBO:0036292
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uridine ribohydrolase Urh2 (predicted)","termid":"PBO:0036292"}


id: GO:0071360
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to exogenous dsRNA","termid":"GO:0043330"},{"relation_name":"is_a","term_name":"cellular response to dsRNA","termid":"GO:0071359"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to exogenous dsRNA","synonyms":[{"name":"cellular response to exogenous double-stranded RNA","type":"exact"},{"name":"cellular response to viral dsRNA","type":"narrow"}],"termid":"GO:0071360"}


id: PBO:0063002
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PAF1 homolog, Paf1/RNA polymerase II complex component","termid":"PBO:0063002"}


id: MONDO:0017139
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Oromandibular-limb hypogenesis syndromes (OLHS) are a group of dysmorphic complexes (including Charlie M syndrome, Hanhart syndrome and glossopalatine ankylosis) characterized by the association of severe asymmetric limb defects (primarily involving distal segments) and abnormalities of the oral cavity and mandible (hypoglossia, aglossia, micrognathia, glossopalatine ankylosis, cleft palate, and gingival anomalies).","definition_xrefs":["Orphanet:2749"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"oromandibular-limb anomalies syndrome","termid":"MONDO:0015498"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"oromandibular-limb hypogenesis syndrome","secondary_identifiers":["MEDGEN:1843329","UMLS:C5679764","icd11.foundation:1665391511","GARD:4116"],"synonyms":[{"name":"Oroacral syndrome","type":"exact"},{"name":"oro-mandibular-limb hypogenesis syndrome","type":"related"}],"termid":"MONDO:0017139","xrefs":{"Monarch":{"xref_id":"0017139"}}}


id: MONDO:0003177
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An adenoid cystic carcinoma that arises from the prostate gland.","definition_xrefs":["NCIT:C5539"],"direct_ancestors":[{"relation_name":"is_a","term_name":"adenoid cystic carcinoma","termid":"MONDO:0004971"},{"relation_name":"is_a","term_name":"prostate adenocarcinoma","termid":"MONDO:0005082"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"prostate adenoid cystic carcinoma","secondary_identifiers":["DOID:4868","MEDGEN:233352","UMLS:C1335502"],"synonyms":[{"name":"adenoid cystic carcinoma of prostate","type":"exact"},{"name":"adenoid cystic carcinoma of the prostate","type":"exact"},{"name":"prostate adenoid cystic carcinoma","type":"exact"},{"name":"prostate gland adenoid cystic carcinoma","type":"exact"}],"termid":"MONDO:0003177","xrefs":{"Monarch":{"xref_id":"0003177"}}}


id: GO:1990705
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The multiplication or reproduction of cholangiocytes, resulting in the expansion of the cholangiocyte population. A cholangiocyte is an epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water.","definition_xrefs":["PMID:24434010"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epithelial cell proliferation","termid":"GO:0050673"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cholangiocyte proliferation","synonyms":[{"name":"hepatoblast proliferation","type":"exact"}],"termid":"GO:1990705"}


id: GO:0001311
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Excision from the chromosome and circularization of DNA molecules encoding ribosomal RNA in dividing cells as they age.","definition_xrefs":["GOC:jh","PMID:12044934"],"gene_count":0,"genotype_count":0,"name":"obsolete formation of extrachromosomal circular rDNA by homologous recombination involved in replicative cell aging (obsolete GO:0001311)","synonyms":[{"name":"assembly of extrachromosomal circular rDNA by homologous recombination involved in replicative cell aging","type":"related"},{"name":"formation of extrachromosomal circular rDNA by homologous recombination during replicative cell ageing","type":"related"},{"name":"formation of extrachromosomal circular rDNA by homologous recombination during replicative cell aging","type":"related"},{"name":"formation of extrachromosomal circular ribosomal DNA by homologous recombination during replicative cell aging","type":"related"}],"termid":"GO:0001311"}


id: GO:0005712
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A connection formed between chromatids, visible during meiosis, thought to be the point of the interchange involved in crossing-over.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"condensed nuclear chromosome","termid":"GO:0000794"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005694"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005634"}],"interesting_parent_ids":["GO:0005634","GO:0005694","GO:0005575"],"is_obsolete":false,"name":"chiasma","secondary_identifiers":["Wikipedia:Chiasma_(genetics)"],"termid":"GO:0005712"}


id: GO:0061529
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The regulated release of epinephrine by a cell in which the epinephrine acts as a neurotransmitter.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epinephrine secretion","termid":"GO:0048242"},{"relation_name":"is_a","term_name":"catecholamine secretion, neurotransmission","termid":"GO:0160043"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0006810","GO:0023052","GO:0008150","GO:0051179"],"is_obsolete":false,"name":"epinephrine secretion, neurotransmission","synonyms":[{"name":"adrenaline secretion, neurotransmission","type":"exact"}],"termid":"GO:0061529"}


id: GO:0070424
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of a nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway (NLR) pathway.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cytoplasmic pattern recognition receptor signaling pathway","termid":"GO:0039531"},{"relation_name":"regulates","term_name":"nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway","termid":"GO:0035872"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway","synonyms":[{"name":"regulation of NOD signaling pathway","type":"narrow"},{"name":"regulation of nucleotide-binding oligomerization domain containing signaling pathway","type":"narrow"},{"name":"regulation of nucleotide-binding oligomerization domain containing signalling pathway","type":"narrow"}],"termid":"GO:0070424"}


id: PBO:0069702
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 982, pseudogene","termid":"PBO:0069702"}


id: GO:0036519
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a serotonergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue.","definition_xrefs":["GOC:PARL","PMID:21106844","CL:0000850","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chemorepulsion of axon","termid":"GO:0061643"},{"relation_name":"part_of","term_name":"serotonergic neuron axon guidance","termid":"GO:0036515"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"chemorepulsion of serotonergic neuron axon","synonyms":[{"name":"chemorepulsion of 5-HT axon","type":"exact"},{"name":"chemorepulsion of serotonergic axon","type":"related"}],"termid":"GO:0036519"}


id: MONDO:0003350
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An aggressive malignant smooth muscle neoplasm. It is characterized by the presence of malignant smooth muscle cells with granular cytoplasmic changes.","definition_xrefs":["NCIT:C27494"],"direct_ancestors":[{"relation_name":"is_a","term_name":"granular cell cancer","termid":"MONDO:0003252"},{"relation_name":"is_a","term_name":"central nervous system leiomyosarcoma","termid":"MONDO:0003349"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"granular cell leiomyosarcoma","secondary_identifiers":["DOID:5258","MEDGEN:234321","UMLS:C1333871"],"synonyms":[{"name":"granular cell leiomyosarcoma","type":"exact"}],"termid":"MONDO:0003350","xrefs":{"Monarch":{"xref_id":"0003350"}}}


id: FYPO:0000426
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which endocytosis is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal vesicle-mediated transport during vegetative growth","termid":"FYPO:0006432"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0001312","FYPO:0001320","FYPO:0000257","FYPO:0000002"],"is_obsolete":false,"name":"normal endocytosis","synonyms":[{"name":"endocytosis: normal","type":"related"},{"name":"normal endocytosis during mitotic cell cycle","type":"related"},{"name":"normal endocytosis during vegetative growth","type":"exact"}],"termid":"FYPO:0000426"}


id: GO:0032220
data:
  {"annotated_genes":["SJAG_02351","SJAG_04887","SJAG_02924","SJAG_00870","SJAG_02878"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[79564,91828,94788,95871,109766],"is_not":false,"summary":null,"term":"GO:0032220"}]},"cv_name":"biological_process","definition":"The joining of two or more lipid bilayer membranes that surround cells, that contributes to cytogamy.","definition_xrefs":["GOC:mah","PMID:29134248"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plasma membrane fusion","termid":"GO:0045026"},{"relation_name":"part_of","term_name":"cytogamy","termid":"GO:0000755"}],"gene_count":5,"genes_by_uniquename":{"SJAG_00870":null,"SJAG_02351":null,"SJAG_02878":null,"SJAG_02924":null,"SJAG_04887":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0000747"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0061024"}],"interesting_parent_ids":["GO:0008150","GO:0061024","GO:0000747"],"is_obsolete":false,"name":"plasma membrane fusion involved in cytogamy","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["GO:0070872"],"synonyms":[{"name":"plasma membrane fusion during cytogamy","type":"related"},{"name":"plasma membrane organization involved in conjugation with cellular fusion","type":"exact"}],"termid":"GO:0032220","terms_by_termid":{"GO:0032220":null}}


id: SO:0100011
data:
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id: PBO:0063755
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PHB1 pseudogene 20","termid":"PBO:0063755"}


id: PBO:0081102
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger E-box binding homeobox 2","termid":"PBO:0081102"}


id: FYPO:0001376
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion measured in a cell during a cellular response to salt stress is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal cellular calcium level","termid":"FYPO:0001199"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001312"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000257","FYPO:0001320","FYPO:0001312"],"is_obsolete":false,"name":"normal cellular calcium level during cellular response to salt stress","synonyms":[{"name":"normal cellular calcium accumulation during cellular response to salt stress","type":"related"},{"name":"normal cellular calcium ion level during cellular response to salt stress","type":"exact"},{"name":"normal cellular calcium level during cellular response to salt stress during mitotic cell cycle","type":"related"},{"name":"normal cellular calcium level during cellular response to salt stress during vegetative growth","type":"exact"}],"termid":"FYPO:0001376"}


id: GO:0045161
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which voltage-gated ion channels become localized to distinct subcellular domains in the neuron. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation.","definition_xrefs":["PMID:11456440"],"direct_ancestors":[{"relation_name":"is_a","term_name":"membrane organization","termid":"GO:0061024"},{"relation_name":"part_of","term_name":"neuron maturation","termid":"GO:0042551"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0061024"}],"interesting_parent_ids":["GO:0008150","GO:0061024"],"is_obsolete":false,"name":"neuronal ion channel clustering","termid":"GO:0045161"}


id: MONDO:0003892
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A morphologic variant of lung adenocarcinoma characterized by the presence of acinar structures composed of columnar or cuboidal cells. (NCI05)","definition_xrefs":["NCIT:C5649"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lung adenocarcinoma","termid":"MONDO:0005061"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"acinar lung adenocarcinoma","secondary_identifiers":["MEDGEN:233130","UMLS:C1332137","DOID:6482"],"synonyms":[{"name":"acinar adenocarcinoma of lung","type":"exact"},{"name":"acinar adenocarcinoma of the lung","type":"exact"},{"name":"acinar lung adenocarcinoma","type":"exact"},{"name":"lung acinar adenocarcinoma","type":"related"}],"termid":"MONDO:0003892","xrefs":{"Monarch":{"xref_id":"0003892"}}}


id: PBO:0068894
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 136, pseudogene","termid":"PBO:0068894"}


id: PR:P78962
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- atf21 gene.","definition_xrefs":["PRO:DNx","UniProtKB:P78962"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcription factor atf21 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC2F12.09c","synonyms":[{"name":"Spom972h-atf21","type":"exact"}],"termid":"PR:P78962"}


id: PBO:0076310
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"synaptojanin 2","termid":"PBO:0076310"}


id: MONDO:0037002
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign, circumscribed fibroepithelial neoplasm arising from the breast and rarely the prostate gland. It is characterized by the presence of epithelial structures which are arranged in clefts and by a hypercellular mesenchymal stroma which is organized in leaf-like structures. There is no evidence of cellular atypia or sarcomatous features.","definition_xrefs":["NCIT:C4274"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phyllodes tumor","termid":"MONDO:0005078"},{"relation_name":"is_a","term_name":"benign neoplasm","termid":"MONDO:0005165"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"benign phyllodes tumor","secondary_identifiers":["ICDO:9020/0","MEDGEN:87254","UMLS:C0334501"],"synonyms":[{"name":"benign cystosarcoma phyllodes","type":"exact"},{"name":"benign phyllodes neoplasm","type":"exact"},{"name":"benign phyllodes tumor","type":"exact"},{"name":"phyllodes tumor, benign","type":"exact"}],"termid":"MONDO:0037002","xrefs":{"Monarch":{"xref_id":"0037002"}}}


id: PBO:0055059
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2475","termid":"PBO:0055059"}


id: FYPO:0000698
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of DNA-7-methylguanine glycosylase activity is decreased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased catalytic activity","termid":"FYPO:0000663"},{"relation_name":"is_a","term_name":"abnormal DNA-7-methylguanine glycosylase activity","termid":"FYPO:0000697"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000707"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000707","FYPO:0000661","FYPO:0000652","FYPO:0000654"],"is_obsolete":false,"name":"decreased DNA-7-methylguanine glycosylase activity","synonyms":[{"name":"reduced DNA-7-methylguanine glycosylase activity","type":"exact"}],"termid":"FYPO:0000698"}


id: SO:0000589
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A primary transcript encoding a signal recognition particle RNA.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nc_primary_transcript","termid":"SO:0000483"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SRP_RNA_primary_transcript","synonyms":[{"name":"SRP RNA primary transcript","type":"exact"}],"termid":"SO:0000589"}


id: PBO:0041337
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 3 open reading frame 20","termid":"PBO:0041337"}


id: GO:2000669
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process.","definition_xrefs":["GOC:mtg_apoptosis","GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of leukocyte apoptotic process","termid":"GO:2000107"},{"relation_name":"is_a","term_name":"regulation of dendritic cell apoptotic process","termid":"GO:2000668"},{"relation_name":"negatively_regulates","term_name":"dendritic cell apoptotic process","termid":"GO:0097048"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of dendritic cell apoptotic process","synonyms":[{"name":"negative regulation of dendritic cell apoptosis","type":"narrow"}],"termid":"GO:2000669"}


id: MONDO:0100556
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A group of rare movement and seizure disorders caused by changes (disease-causing variants or mutations) in the PRRT2 gene. They include a spectrum of specific disorders including paroxysmal kinesigenic dyskinesia (PKD), benign familial infantile epilepsy (BFIE), paroxysmal kinesigenic dyskinesia with infantile convulsions (PKD/IC) and hemiplegic migraine (HM). In addition, PRRT2 pathogenic variants have been identified in other childhood-onset movement disorders and different types of seizure conditions, such as paroxysmal torticollis, episodic ataxia and familial paroxysmal non-kinesigenic dyskinesia. It’s important to note that these disorders can also have different genetic causes.","definition_xrefs":["PMID:32916768","PMID:33746883"],"direct_ancestors":[{"relation_name":"is_a","term_name":"movement disorder","termid":"MONDO:0005395"},{"relation_name":"is_a","term_name":"hereditary neurological disease","termid":"MONDO:0100545"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PRRT2-associated paroxysmal movement disorder","termid":"MONDO:0100556","xrefs":{"Monarch":{"xref_id":"0100556"}}}


id: GO:0046902
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.","definition_xrefs":["GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mitochondrial membrane organization","termid":"GO:0007006"},{"relation_name":"is_a","term_name":"regulation of membrane permeability","termid":"GO:0090559"},{"relation_name":"part_of","term_name":"mitochondrial transport","termid":"GO:0006839"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0007005"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0061024"}],"interesting_parent_ids":["GO:0061024","GO:0006810","GO:0008150","GO:0007005"],"is_obsolete":false,"name":"regulation of mitochondrial membrane permeability","synonyms":[{"name":"regulation of mitochondrial envelope permeability","type":"related"},{"name":"regulation of transport across mitochondrial membrane","type":"exact"}],"termid":"GO:0046902"}


id: PBO:0041137
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"betacellulin","termid":"PBO:0041137"}


id: GO:0038100
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a nodal protein, a member of the transforming growth factor-beta superfamily.","definition_xrefs":["PMID:20629020","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein binding","termid":"GO:0005515"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0005515"}],"interesting_parent_ids":["GO:0003674","GO:0005515","GO:0005488"],"is_obsolete":false,"name":"nodal binding","termid":"GO:0038100"}


id: FYPO:0005850
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin at centromere outer repeat regions does not occur.","definition_xrefs":["PMID:27648579","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished protein localization to pericentric heterochromatin during vegetative growth","termid":"FYPO:0003074"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0001320","FYPO:0000002","FYPO:0005447","FYPO:0001985"],"is_obsolete":false,"name":"abolished protein localization to heterochromatin at centromere outer repeat","synonyms":[{"name":"abolished protein localisation to chromatin at centromere outer repeat","type":"exact"},{"name":"abolished protein localisation to heterochromatin at centromere outer repeat","type":"exact"},{"name":"abolished protein localization at centromere otr","type":"exact"},{"name":"abolished protein localization at centromeric outer repeat region","type":"exact"},{"name":"abolished protein localization at pericentric region","type":"related"},{"name":"abolished protein localization at pericentromeric region","type":"related"},{"name":"abolished protein localization to centromere outer repeat heterochromatin","type":"exact"},{"name":"abolished protein localization to chromatin at centromere otr","type":"exact"},{"name":"abolished protein localization to chromatin at centromere outer repeat","type":"exact"},{"name":"abolished protein localization to chromatin at centromere outer repeat during mitotic cell cycle","type":"related"},{"name":"abolished protein localization to chromatin at centromere outer repeat during vegetative growth","type":"exact"},{"name":"abolished protein localization to chromatin at centromeric outer repeat","type":"exact"},{"name":"abolished protein localization to chromatin at pericentric region","type":"related"},{"name":"abolished protein localization to chromatin at pericentromeric region","type":"related"},{"name":"abolished protein localization to heterochromatin at centromere outer repeat during mitotic cell cycle","type":"related"},{"name":"abolished protein localization to heterochromatin at centromere outer repeat during vegetative growth","type":"exact"},{"name":"protein localization to heterochromatin at centromere outer repeat abolished","type":"exact"}],"termid":"FYPO:0005850"}


id: MOD:00157
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-tryptophan residue to an L-tryptophan quinone.","definition_xrefs":["Unimod:392#W","DeltaMass:0","RESID:AA0148","PubMed:2028257"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbon oxygenated residue","termid":"MOD:00679"},{"relation_name":"is_a","term_name":"modified L-tryptophan residue","termid":"MOD:00918"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"L-tryptophyl quinone","synonyms":[{"name":"(2S)-2-amino-3-(6,7-dioxo-1H-indol-3-yl)propanoic acid","type":"exact"},{"name":"2-amino-3-(6,7-dioxo-6,7-dihydro-1H-indol-3-yl)-propionic acid","type":"exact"},{"name":"3-[(2S)-2-amino-2-carboxyethyl]-6,7-indolinedione","type":"exact"},{"name":"6,7 Dione (from Tryptophan)","type":"exact"},{"name":"L-tryptophyl quinone","type":"exact"},{"name":"MOD_RES Tryptophylquinone","type":"exact"},{"name":"N-(3-carboxy-1-oxopropyl)-L-tryptophan","type":"exact"},{"name":"Quinone","type":"related"},{"name":"TrpQ","type":"exact"},{"name":"quinone","type":"related"}],"termid":"MOD:00157"}


id: PBO:0004312
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NatC N-acetyltransferase complex catalytic subunit Naa30 (predicted)","termid":"PBO:0004312"}


id: PBO:0082294
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Arginosuccinate synthetase; catalyzes the formation of L-argininosuccinate from citrulline and L-aspartate in the arginine biosynthesis pathway; potential Cdc28p substrate","termid":"PBO:0082294"}


id: GO:0062140
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A septin collar in pathogenic fungi involved in the constriction of hyphae at the plant plasmodesma enabling penetration of an adjacent cell.","definition_xrefs":["PMID:29567712"],"direct_ancestors":[{"relation_name":"is_a","term_name":"septin collar","termid":"GO:0032173"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"hyphae septin collar","synonyms":[{"name":"septin collar of invasive hyphae","type":"related"}],"termid":"GO:0062140"}


id: PBO:0073836
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SLC7A11 antisense RNA 1","termid":"PBO:0073836"}


id: PBO:0074418
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small integral membrane protein 17","termid":"PBO:0074418"}


id: PBO:0086167
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein required for spore wall maturation; expressed during sporulation; may be a component of the spore wall; expression also induced in cells treated with the mycotoxin patulin; SPS100 has a paralog, YGP1, that arose from the whole genome duplication","termid":"PBO:0086167"}


id: GO:0035447
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 1D-myo-inositol-2-(L-cysteinylamido)-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA = mycothiol + coA + H+. Mycothiol is also known as AcCys-GlcN-Ins and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as Cys-GlcN-Ins or desacetylmycothiol.","definition_xrefs":["EC:2.3.1.189","PMID:12033919"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acyltransferase activity, transferring groups other than amino-acyl groups","termid":"GO:0016747"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016746"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016740","GO:0016746"],"is_obsolete":false,"name":"mycothiol synthase activity","secondary_identifiers":["MetaCyc:RXN1G-4","RHEA:26172"],"synonyms":[{"name":"acetyl-CoA:Cys-GlcN-Ins acetyltransferase","type":"exact"}],"termid":"GO:0035447"}


id: MONDO:1011653
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"musculoskeletal system disorder, non-human animal","termid":"MONDO:1011335"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"craniomandibular osteopathy, non-human animal","secondary_identifiers":["OMIA:000236"],"termid":"MONDO:1011653","xrefs":{"Monarch":{"xref_id":"1011653"}}}


id: MONDO:1010137
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Bullous pemphigoid that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inflammatory disease, non-human animal","termid":"MONDO:1011327"},{"relation_name":"is_a","term_name":"integumentary system disorder, non-human animal","termid":"MONDO:1011328"},{"relation_name":"is_a","term_name":"autoimmune disease, non-human animal","termid":"MONDO:1012985"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bullous pemphigoid, non-human animal","secondary_identifiers":["OMIA:001183"],"termid":"MONDO:1010137","xrefs":{"Monarch":{"xref_id":"1010137"}}}


id: PBO:0054569
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1971","termid":"PBO:0054569"}


id: PBO:0073490
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"shugoshin 2","termid":"PBO:0073490"}


id: FYPO:0000581
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell population phenotype in which the frequency of occurrence of spore germination is decreased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell population phenotype","termid":"FYPO:0000003"},{"relation_name":"is_a","term_name":"abnormal phenotype","termid":"FYPO:0001985"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000003","FYPO:0001985"],"is_obsolete":false,"name":"decreased spore germination frequency","synonyms":[{"name":"decreased spore germination","type":"exact"},{"name":"decreased spore viability","type":"related"},{"name":"reduced spore germination frequency","type":"exact"},{"name":"reduced spore viability","type":"related"},{"name":"spore germination: decreased","type":"related"}],"termid":"FYPO:0000581"}


id: MONDO:0002097
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete ocular melanoma (obsolete MONDO:0002097)","termid":"MONDO:0002097","xrefs":{"Monarch":{"xref_id":"0002097"}}}


id: PBO:0028660
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_protein_complex_binding","termid":"PBO:0028660"}


id: PBO:0064594
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"POU class 1 homeobox 1","termid":"PBO:0064594"}


id: PR:O60179
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- utp10 gene.","definition_xrefs":["UniProtKB:O60179","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"U3 small nucleolar RNA-associated protein 10 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC23E6.04c","synonyms":[{"name":"Spom972h-utp10","type":"exact"},{"name":"U3 protein 10 required for transcription (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"U3 snoRNA-associated protein 10 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O60179"}


id: GO:0021593
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.","definition_xrefs":["GOC:cls","GOC:jid","GOC:dgh","GOC:dph","GO_REF:0000021","ISBN:0838580343"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure morphogenesis","termid":"GO:0009653"},{"relation_name":"part_of","term_name":"rhombomere development","termid":"GO:0021546"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"rhombomere morphogenesis","termid":"GO:0021593"}


id: PBO:0046239
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"elongin C pseudogene 33","termid":"PBO:0046239"}


id: GO:0170057
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the joining of an RNA with 3'-phosphate or 2',3'-cyclic-phosphate ends to an RNA with 5'-hydroxy ends according to either (i) a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP = a ribonucleotidyl-ribonucleotide-RNA + diphosphate + GMP; or (ii) a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP + H2O = a ribonucleotidyl-ribonucleotide-RNA + diphosphate + GMP + H+.","definition_xrefs":["EC:6.5.1.8","PMID:21311021"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA ligase activity","termid":"GO:0008452"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016874"},{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0140098","GO:0016874"],"is_obsolete":false,"name":"RNA ligase (GTP) activity","synonyms":[{"name":"3'-phosphate/5'-hydroxy nucleic acid ligase activity","type":"exact"}],"termid":"GO:0170057"}


id: PBO:0041069
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"brain protein I3 pseudogene 2","termid":"PBO:0041069"}


id: GO:0021949
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The early migration of a precerebellar neuronal precursor in which a cell move from the rhombic lip, orthogonal to the direction of radial migration and ultimately reside in the brainstem.","definition_xrefs":["GOC:dgh","GO_REF:0000021","GOC:dph","GOC:cls","PMID:15157725","GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hindbrain tangential cell migration","termid":"GO:0021934"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"brainstem precerebellar neuron precursor migration","termid":"GO:0021949"}


id: MONDO:0000680
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An agnosia that is the loss of the ability to recognize objects by touch based on its texture, size and weight.","definition_xrefs":["DOID:0060150"],"direct_ancestors":[{"relation_name":"is_a","term_name":"agnosia","termid":"MONDO:0005638"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"astereognosia","secondary_identifiers":["UMLS:C0234505","HP:0010527","icd11.foundation:756147896","MEDGEN:65881"],"synonyms":[{"name":"astereognosia","type":"exact"},{"name":"astereognosia (disease)","type":"exact"},{"name":"somatosensory agnosia","type":"exact"}],"termid":"MONDO:0000680","xrefs":{"Monarch":{"xref_id":"0000680"}}}


id: PBO:0089332
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HSP chaperone complex subunit Cns1","termid":"PBO:0089332"}


id: GO:0016623
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces oxygen.","definition_xrefs":["EC:1.2.3.-"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the aldehyde or oxo group of donors","termid":"GO:0016903"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor","termid":"GO:0016623"}


id: MONDO:0001914
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare form of necrotizing anterior scleritis without pain in which the sclera is notably white, avascular and thin. Both choroidal exposure and staphyloma formation may occur.","direct_ancestors":[{"relation_name":"is_a","term_name":"necrotizing scleritis","termid":"MONDO:0040699"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"scleromalacia perforans","secondary_identifiers":["DOID:14230","icd11.foundation:740830358","MEDGEN:509929","UMLS:C0155354","SCTID:26664005","ICD9:379.04"],"termid":"MONDO:0001914","xrefs":{"Monarch":{"xref_id":"0001914"}}}


id: GO:1904001
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of pyrimidine-containing compound salvage.","definition_xrefs":["PMID:23695302","GOC:TermGenie","GOC:al","GO_REF:0000063"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter (obsolete GO:1904001)","synonyms":[{"name":"activation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter","type":"related"},{"name":"activation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter","type":"narrow"},{"name":"positive regulation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter","type":"related"},{"name":"up regulation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter","type":"related"},{"name":"up regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"up-regulation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter","type":"related"},{"name":"up-regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"upregulation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter","type":"related"},{"name":"upregulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter","type":"exact"}],"termid":"GO:1904001"}


id: MONDO:0005547
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete desmoplastic medulloblastoma (obsolete MONDO:0005547)","termid":"MONDO:0005547","xrefs":{"Monarch":{"xref_id":"0005547"}}}


id: PBO:0091237
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aminomethyltransferase-like and DUF1989 family protein, implicated in urea metabolism","termid":"PBO:0091237"}


id: GO:0099085
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 1-[(3,5-dichloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one => 1-[(3-chloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one + Cl-.","definition_xrefs":["PMID:1521542","PMID:22035794"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbon-halide lyase activity","termid":"GO:0016848"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016829"],"is_obsolete":false,"name":"DIF dechlorinase activity","synonyms":[{"name":"1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one 3(5)-dechlorinase activity","type":"exact"},{"name":"1-[(3,5-dichloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one 3(5)-dechlorinase activity","type":"exact"},{"name":"DIF-1 3(5)-dechlorinase activity","type":"exact"},{"name":"DIF-1 dechlorinase activity","type":"exact"},{"name":"differentiation-inducing factor 1 dechlorinase activity","type":"exact"},{"name":"differentiation-inducing factor dechlorinase activity","type":"exact"}],"termid":"GO:0099085"}


id: FYPO:0001280
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to oxidative stress is lower than normal. Total RNA or a specific RNA may be affected.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased RNA level during vegetative growth","termid":"FYPO:0001117"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0006551"},{"rel_name":"output_of","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000002","FYPO:0005447","FYPO:0001985","FYPO:0006551"],"is_obsolete":false,"name":"decreased RNA level during cellular response to oxidative stress","synonyms":[{"name":"decreased RNA accumulation during cellular response to oxidative stress","type":"related"},{"name":"decreased RNA level during cellular response to DEM","type":"narrow"},{"name":"decreased RNA level during cellular response to diethyl maleate","type":"narrow"},{"name":"decreased RNA level during cellular response to oxidative stress during mitotic cell cycle","type":"related"},{"name":"decreased RNA level during cellular response to oxidative stress during vegetative growth","type":"exact"},{"name":"decreased RNA level during oxidative stress response","type":"exact"},{"name":"decreased mRNA level during cellular response to oxidative stress","type":"narrow"},{"name":"decreased transcript level during cellular response to oxidative stress","type":"exact"},{"name":"reduced RNA level during cellular response to oxidative stress","type":"exact"}],"termid":"FYPO:0001280"}


id: GO:0062139
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of a light-responsive receptor in a camera-type eye over time, from its formation to the mature structure.","definition_xrefs":["PMID:20648062","PMID:30237290"],"direct_ancestors":[{"relation_name":"is_a","term_name":"eye photoreceptor cell development","termid":"GO:0042462"},{"relation_name":"part_of","term_name":"camera-type eye development","termid":"GO:0043010"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"camera-type eye photoreceptor cell development","termid":"GO:0062139"}


id: PBO:0017775
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"conserved fungal protein Nst1","termid":"PBO:0017775"}


id: GO:0047051
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (R)-lactate + 2 [Fe(III)cytochrome c553] = 2 [Fe(II)cytochrome c553] + 2 H+ + pyruvate.","definition_xrefs":["RHEA:16465"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor","termid":"GO:0016898"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"D-lactate dehydrogenase (cytochrome c-553) activity","secondary_identifiers":["EC:1.1.2.5","MetaCyc:1.1.2.5-RXN"],"synonyms":[{"name":"(R)-lactate:ferricytochrome-c-553 2-oxidoreductase activity","type":"related"}],"termid":"GO:0047051"}


id: PBO:0046345
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ectonucleotide pyrophosphatase/phosphodiesterase 7 pseudogene 3","termid":"PBO:0046345"}


id: MONDO:0014286
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any hereditary sensory and autonomic neuropathy type 1 in which the cause of the disease is a mutation in the ATL3 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary sensory and autonomic neuropathy type 1","termid":"MONDO:0018213"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005244"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0002525"}],"interesting_parent_ids":["MONDO:0002525","MONDO:0005066","MONDO:0005244"],"is_obsolete":false,"name":"neuropathy, hereditary sensory, type 1F","secondary_identifiers":["UMLS:C3810194","OMIM:615632","DOID:0070154","MEDGEN:816524","GARD:15995"],"synonyms":[{"name":"ATL3 hereditary sensory and autonomic neuropathy type 1","type":"exact"},{"name":"HSN 1F","type":"related"},{"name":"HSN1F","type":"exact"},{"name":"hereditary sensory and autonomic neuropathy type 1 caused by mutation in ATL3","type":"exact"},{"name":"hereditary sensory neuropathy type 1F","type":"related"},{"name":"hereditary sensory neuropathy type IF","type":"exact"},{"name":"neuropathy, hereditary sensory, type 1F","type":"exact"},{"name":"neuropathy, hereditary sensory, type IF","type":"related"}],"termid":"MONDO:0014286","xrefs":{"Monarch":{"xref_id":"0014286"}}}


id: SO:1001217
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A gene that is a member of a group of genes that are either regulated or transcribed together.","direct_ancestors":[{"relation_name":"is_a","term_name":"gene_array_member","termid":"SO:0000081"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"member_of_regulon","synonyms":[{"name":"member of regulon","type":"exact"}],"termid":"SO:1001217"}


id: MONDO:0011015
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A cataract that has material basis in variation in the region 17p13.","definition_xrefs":["DOID:0110257","PMID:8852669"],"direct_ancestors":[{"relation_name":"is_a","term_name":"early-onset anterior polar cataract","termid":"MONDO:0020373"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"cataract 24","secondary_identifiers":["UMLS:C1832609","OMIM:601202","MESH:C537774","GARD:15327","MEDGEN:371364"],"synonyms":[{"name":"CTAA2","type":"narrow"},{"name":"CTRCT24","type":"exact"},{"name":"anterior polar cataract 2","type":"narrow"},{"name":"anterior polar cataract 24","type":"narrow"},{"name":"cataract 24","type":"exact"},{"name":"cataract 24, anterior polar","type":"related"},{"name":"cataract type 24","type":"exact"},{"name":"cataract, anterior polar, 2","type":"related"}],"termid":"MONDO:0011015","xrefs":{"Monarch":{"xref_id":"0011015"}}}


id: MONDO:0009802
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"osteodysplasty, precocious, of Danks, Mayne, and Kozlowski","secondary_identifiers":["MESH:C564922","OMIM:259270","UMLS:C1850185","MEDGEN:337989"],"synonyms":[{"name":"Danks Mayne Kozlowski precocious osteodysplasty","type":"related"},{"name":"osteodysplasty precocious of Danks Mayne and Kozlowski","type":"related"},{"name":"osteodysplasty, precocious, of Danks, Mayne, and Kozlowski","type":"exact"}],"termid":"MONDO:0009802","xrefs":{"Monarch":{"xref_id":"0009802"}}}


id: MONDO:0011935
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any retinitis pigmentosa in which the cause of the disease is a mutation in the FSCN2 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"retinitis pigmentosa","termid":"MONDO:0019200"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004736"},{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328","MONDO:0005066","MONDO:0004736"],"is_obsolete":false,"name":"retinitis pigmentosa 30","secondary_identifiers":["UMLS:C1842816","MEDGEN:334614","DOID:0110406","GARD:10401","OMIM:607921","ICD10CM:H35.5"],"synonyms":[{"name":"FSCN2 retinitis pigmentosa","type":"exact"},{"name":"RP 30","type":"related"},{"name":"RP30","type":"exact"},{"name":"macular Degeneration","type":"related"},{"name":"retinitis pigmentosa 30","type":"exact"},{"name":"retinitis pigmentosa caused by mutation in FSCN2","type":"exact"},{"name":"retinitis pigmentosa type 30","type":"exact"}],"termid":"MONDO:0011935","xrefs":{"Monarch":{"xref_id":"0011935"}}}


id: MONDO:0017946
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hereditary cerebral hemorrhage with amyloidosis (HCHWA), Iowa type is a form of HCHWA characterized by age of onset between 50-66 years of age, memory impairment, myoclonic jerks, expressive dysphagia, short-stepped gait, personality changes and lobar intracerebral hemorrhages.","definition_xrefs":["Orphanet:324708"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cerebral amyloid angiopathy, APP-related","termid":"MONDO:0011583"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0021179"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0021179","MONDO:0005066"],"is_obsolete":false,"name":"ABeta amyloidosis, Iowa type","secondary_identifiers":["ICD10EXP:E85.4+","UMLS:C3888309","GARD:17490","MEDGEN:854855","ICD10EXP:I68.0*"],"synonyms":[{"name":"ABetaD23N amyloidosis","type":"exact"},{"name":"HCHWA, Iowa type","type":"exact"},{"name":"cerebral amyloid angiopathy, APP-related, Iowa variant","type":"exact"},{"name":"hereditary cerebral haemorrhage with amyloidosis, Iowa type","type":"exact"},{"name":"hereditary cerebral hemorrhage with amyloidosis, Iowa type","type":"exact"}],"termid":"MONDO:0017946","xrefs":{"Monarch":{"xref_id":"0017946"}}}


id: GO:0090091
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.","definition_xrefs":["GOC:tb","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of extracellular matrix disassembly","termid":"GO:0010715"},{"relation_name":"is_a","term_name":"positive regulation of extracellular matrix organization","termid":"GO:1903055"},{"relation_name":"positively_regulates","term_name":"extracellular matrix disassembly","termid":"GO:0022617"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of extracellular matrix disassembly","termid":"GO:0090091"}


id: PBO:0005543
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3.1.3.57","termid":"PBO:0005543"}


id: PBO:0029364
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_histone_methylation","termid":"PBO:0029364"}


id: GO:0090447
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: an acyl-CoA + sn-glycerol 3-phosphate = CoA + a 2-acyl-sn-glycerol 3-phosphate.","definition_xrefs":["RHEA:33559"],"direct_ancestors":[{"relation_name":"is_a","term_name":"O-acyltransferase activity","termid":"GO:0008374"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016746","GO:0016740","GO:0003824"],"is_obsolete":false,"name":"glycerol-3-phosphate 2-O-acyltransferase activity","secondary_identifiers":["EC:2.3.1.198"],"termid":"GO:0090447"}


id: GO:0005429
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Enables the transfer of amines across chromaffin granule membranes.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete chromaffin granule amine transmembrane transporter activity (obsolete GO:0005429)","termid":"GO:0005429"}


id: MONDO:0044709
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"middle ear anomaly","termid":"MONDO:0015604"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cochleovestibular dysplasia","secondary_identifiers":["Orphanet:502305","MEDGEN:1818562","GARD:22044","UMLS:C5761642"],"termid":"MONDO:0044709","xrefs":{"Monarch":{"xref_id":"0044709"}}}


id: GO:0102295
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 4-methylumbelliferyl glucoside + malonyl-CoA = 4-methylumbelliferone 6'-O-malonylglucoside + coenzyme A.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete 4-methylumbelliferyl glucoside 6'-O-malonyltransferase activity (obsolete GO:0102295)","termid":"GO:0102295"}


id: MONDO:0018994
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A subtype of Charcot-Marie-Tooth disease with genetic defects on the X chromosome.","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"hereditary motor and sensory neuropathy","termid":"MONDO:0015358"},{"relation_name":"excluded_subClassOf","term_name":"X-linked syndromic intellectual disability","termid":"MONDO:0020119"},{"relation_name":"is_a","term_name":"X-linked disease","termid":"MONDO:0000425"},{"relation_name":"is_a","term_name":"Charcot-Marie-Tooth disease","termid":"MONDO:0015626"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0005244"],"is_obsolete":false,"name":"Charcot-Marie-Tooth disease type X","secondary_identifiers":["SCTID:230552007","ICD9:356.9","GARD:12444","UMLS:C4551551","Orphanet:64747","DOID:0050542","MEDGEN:1637021"],"synonyms":[{"name":"CMTX","type":"exact"},{"name":"COWCK","type":"exact"},{"name":"X-linked Charcot-Marie-Tooth disease","type":"related"},{"name":"X-linked hereditary motor and sensory neuropathy","type":"exact"}],"termid":"MONDO:0018994","xrefs":{"Monarch":{"xref_id":"0018994"}}}


id: PBO:0073845
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 8 member B1","termid":"PBO:0073845"}


id: PBO:0076057
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"stomatin like 3","termid":"PBO:0076057"}


id: GO:0090088
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.","definition_xrefs":["GOC:tb","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of peptide transport","termid":"GO:0090087"},{"relation_name":"regulates","term_name":"oligopeptide transport","termid":"GO:0006857"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0006810"],"is_obsolete":false,"name":"regulation of oligopeptide transport","termid":"GO:0090088"}


id: PBO:0066321
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RBX1 pseudogene 1","termid":"PBO:0066321"}


id: MONDO:0016766
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. Lichen planus (LP) is a common inflammatory dermatosis characterized by the development of pruritic violaceous papules or plaques on mucocutaneous surfaces. Eruptions can involve the face, neck, limbs, back, genitalia, tongue, buccal mucosa, nails, and scalp. LP comprises rare variants affecting the skin and the mucosa. Rare cutaneous LP includes linear LP (referring to blaschkoid and zosteriform distributions of lichenoid lesions), actinic LP, annular LP, atrophic LP, annular atrophic LP, lichen planopilaris (comprising Graham Little-Piccardi-Lassueur syndrome and frontal fibrosing alopecia), lichen planus pigmentosus, and lichen planus pemphigoides. Rare mucosal LP includes vulvovaginal gingival syndrome and LP sialadenitis.","definition_xrefs":["Orphanet:254367"],"gene_count":0,"genotype_count":0,"name":"obsolete rare lichen planus (obsolete MONDO:0016766)","synonyms":[{"name":"rare LP","type":"exact"},{"name":"rare lichen planus","type":"exact"}],"termid":"MONDO:0016766","xrefs":{"Monarch":{"xref_id":"0016766"}}}


id: PBO:0034625
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_telomerase_RNA_reverse_transcriptase_activity","termid":"PBO:0034625"}


id: GO:0004373
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: [(1->4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)-alpha-D-glucosyl](n+1) + H+ + UDP.","definition_xrefs":["RHEA:18549"],"direct_ancestors":[{"relation_name":"is_a","term_name":"alpha-1,4-glucan glucosyltransferase (NDP-glucose donor) activity","termid":"GO:0033840"},{"relation_name":"is_a","term_name":"UDP-glucosyltransferase activity","termid":"GO:0035251"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016757"}],"interesting_parent_ids":["GO:0016740","GO:0003824","GO:0016757","GO:0003674"],"is_obsolete":false,"name":"alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity","secondary_identifiers":["Reactome:R-HSA-3858506","EC:2.4.1.11","MetaCyc:RXN-7668","Reactome:R-HSA-3322001","Reactome:R-HSA-3828061","Reactome:R-HSA-3322041","Reactome:R-HSA-3322009"],"synonyms":[{"name":"UDP-glucose-glycogen glucosyltransferase activity","type":"related"},{"name":"UDP-glucose:glycogen 4-alpha-D-glucosyltransferase activity","type":"related"},{"name":"UDP-glycogen synthase activity","type":"related"},{"name":"UDPG-glycogen synthetase activity","type":"related"},{"name":"UDPG-glycogen transglucosylase activity","type":"related"},{"name":"UDPglucose:glycogen 4-alpha-D-glucosyltransferase activity","type":"related"},{"name":"glycogen (starch) synthetase activity","type":"exact"},{"name":"glyucogen (starch) synthase activity","type":"exact"},{"name":"uridine diphosphoglucose-glycogen glucosyltransferase activity","type":"related"}],"termid":"GO:0004373"}


id: PR:P36582
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- pck1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:P36582"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein kinase C-like 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC17G8.14c","synonyms":[{"name":"Spom972h-pck1","type":"exact"}],"termid":"PR:P36582"}


id: PBO:0073914
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SLC16A4 antisense RNA 1","termid":"PBO:0073914"}


id: GO:0010594
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.","definition_xrefs":["GOC:tb","GOC:dph","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cell migration","termid":"GO:0030334"},{"relation_name":"regulates","term_name":"endothelial cell migration","termid":"GO:0043542"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of endothelial cell migration","termid":"GO:0010594"}


id: PBO:0043940
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CRTC3 antisense RNA 1","termid":"PBO:0043940"}


id: PBO:0030484
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_sodium_export","termid":"PBO:0030484"}


id: GO:1903242
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of cardiac muscle hypertrophy in response to stress.","definition_xrefs":["GOC:TermGenie","GOC:BHF","GO_REF:0000058","PMID:19287093","GOC:rl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cardiac muscle hypertrophy","termid":"GO:0010611"},{"relation_name":"is_a","term_name":"regulation of cardiac muscle adaptation","termid":"GO:0010612"},{"relation_name":"is_a","term_name":"regulation of response to stress","termid":"GO:0080134"},{"relation_name":"regulates","term_name":"cardiac muscle hypertrophy in response to stress","termid":"GO:0014898"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of cardiac muscle hypertrophy in response to stress","termid":"GO:1903242"}


id: PBO:0116437
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA metabolism factor Tan1","termid":"PBO:0116437"}


id: PBO:0002458
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP phosphoribosyltransferase","termid":"PBO:0002458"}


id: PBO:0085642
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein involved in lipid droplet (LD) assembly; forms a complex with Sei1p at ER-LD contact sites, stabilizing contact sites; ensures that LDs bud from the ER towards the cytosolic side of the membrane; null mutants have decreased net negative cell surface charge and localized accumulation of phosphatidic acid (PA) marker proteins; GFP-fusion protein expression is induced in response to MMS; null mutant can be complemented by the human seipin, BSCL2","termid":"PBO:0085642"}


id: PBO:0044376
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CYMP antisense RNA 1","termid":"PBO:0044376"}


id: GO:1905365
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of intralumenal vesicle formation.","definition_xrefs":["GOC:TermGenie","GOC:PARL","GOC:bc","GO_REF:0000058","PMID:26911690"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of endosome organization","termid":"GO:1904978"},{"relation_name":"regulates","term_name":"intralumenal vesicle formation","termid":"GO:0070676"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0061024"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0061024","GO:0008150"],"is_obsolete":false,"name":"regulation of intralumenal vesicle formation","synonyms":[{"name":"regulation of endosome membrane budding","type":"exact"}],"termid":"GO:1905365"}


id: PBO:0056490
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MYC associated zinc finger protein","termid":"PBO:0056490"}


id: GO:1903765
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion export across the plasma membrane.","definition_xrefs":["GOC:mtg_cardiac_conduct_nov11","GOC:BHF","GOC:rl","GOC:TermGenie","PMID:19646991","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of potassium ion transmembrane transport","termid":"GO:1901380"},{"relation_name":"is_a","term_name":"regulation of potassium ion export across plasma membrane","termid":"GO:1903764"},{"relation_name":"negatively_regulates","term_name":"potassium ion export across plasma membrane","termid":"GO:0097623"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0006810"},{"rel_name":"negatively_regulates","termid":"GO:0055085"},{"rel_name":"regulates","termid":"GO:0055085"}],"interesting_parent_ids":["GO:0055085","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"negative regulation of potassium ion export across plasma membrane","secondary_identifiers":["GO:1902303"],"synonyms":[{"name":"down regulation of potassium export","type":"broad"},{"name":"down regulation of potassium ion export","type":"broad"},{"name":"down regulation of potassium ion export across plasma membrane","type":"exact"},{"name":"down-regulation of potassium export","type":"broad"},{"name":"down-regulation of potassium ion export","type":"broad"},{"name":"down-regulation of potassium ion export across plasma membrane","type":"exact"},{"name":"downregulation of potassium export","type":"broad"},{"name":"downregulation of potassium ion export","type":"broad"},{"name":"downregulation of potassium ion export across plasma membrane","type":"exact"},{"name":"inhibition of potassium export","type":"narrow"},{"name":"inhibition of potassium ion export","type":"related"},{"name":"inhibition of potassium ion export across plasma membrane","type":"exact"},{"name":"negative regulation of potassium export","type":"broad"},{"name":"negative regulation of potassium ion export","type":"broad"}],"termid":"GO:1903765"}


id: PBO:0005399
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADPH-dependent FMN reductase (predicted)","termid":"PBO:0005399"}


id: PBO:0084856
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial ribosomal protein of the large subunit; overproduction suppresses mutations in the COX2 leader peptide-encoding region","termid":"PBO:0084856"}


id: MONDO:0004116
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An aggressive, high-grade and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the esophagus. It is characterized by the presence of malignant small cells.","definition_xrefs":["NCIT:C6762"],"direct_ancestors":[{"relation_name":"is_a","term_name":"small cell carcinoma","termid":"MONDO:0000402"},{"relation_name":"is_a","term_name":"esophageal neuroendocrine tumor","termid":"MONDO:0003649"},{"relation_name":"is_a","term_name":"carcinoma of esophagus","termid":"MONDO:0019086"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0004335"],"is_obsolete":false,"name":"esophageal small cell neuroendocrine carcinoma","secondary_identifiers":["DOID:7134","MEDGEN:207270","UMLS:C1112474"],"synonyms":[{"name":"Oat cell carcinoma of esophagus","type":"exact"},{"name":"Oat cell carcinoma of oesophagus","type":"exact"},{"name":"Oat cell carcinoma of the esophagus","type":"exact"},{"name":"Oat cell carcinoma of the oesophagus","type":"exact"},{"name":"esophageal Oat cell carcinoma","type":"exact"},{"name":"esophageal small cell NEC","type":"exact"},{"name":"esophageal small cell carcinoma","type":"exact"},{"name":"esophageal small cell neuroendocrine carcinoma","type":"exact"},{"name":"esophagus Oat cell carcinoma","type":"exact"},{"name":"esophagus small cell carcinoma","type":"exact"},{"name":"oesophagus Oat cell carcinoma","type":"exact"},{"name":"oesophagus small cell carcinoma","type":"exact"},{"name":"small cell carcinoma of esophagus","type":"exact"},{"name":"small cell carcinoma of oesophagus","type":"exact"},{"name":"small cell carcinoma of the esophagus","type":"exact"},{"name":"small cell carcinoma of the oesophagus","type":"exact"},{"name":"small cell carcinoma, esophagus","type":"exact"},{"name":"small cell carcinoma, oesophagus","type":"exact"}],"termid":"MONDO:0004116","xrefs":{"Monarch":{"xref_id":"0004116"}}}


id: PBO:0066951
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RN7SK pseudogene 253","termid":"PBO:0066951"}


id: FYPO:0006236
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain a normal (i.e. indistinguishable from wild type) number of monomeric ribosomes (80S monosomes) in the cytosol.","definition_xrefs":["PomBase:mah","PMID:18065650"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal level of macromolecular complex","termid":"FYPO:0006235"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000257","FYPO:0001320"],"is_obsolete":false,"name":"normal cytosolic monomeric ribosome level","synonyms":[{"name":"cytosolic monomeric ribosomes present at normal level","type":"exact"},{"name":"normal cytosolic 80S monosome level","type":"exact"},{"name":"normal cytosolic monomeric 80S ribosome level","type":"exact"},{"name":"normal cytosolic monomeric ribosome level during mitotic cell cycle","type":"related"},{"name":"normal cytosolic monomeric ribosome level during vegetative growth","type":"exact"},{"name":"normal cytosolic ribosome level","type":"broad"},{"name":"normal level of cytosolic monomeric ribosomes","type":"exact"}],"termid":"FYPO:0006236"}


id: PBO:0005340
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2.1.2.3","termid":"PBO:0005340"}


id: PBO:0034050
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-in_structural_homology_relationship_with","termid":"PBO:0034050"}


id: GO:1990085
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex involved in inactivating the function of DnaA and thereby preventing multiple events of replication initiation. In E. coli, this complex is composed of the beta clamp (DnaN) and Hda.","definition_xrefs":["GOC:bhm","PMID:15150238"],"direct_ancestors":[{"relation_name":"is_a","term_name":"replication inhibiting complex","termid":"GO:1990078"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005694"},{"rel_name":"part_of","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0005694","GO:0032991"],"is_obsolete":false,"name":"Hda-beta clamp complex","synonyms":[{"name":"Hda-DnaN complex","type":"exact"},{"name":"Hda-dpo3b complex","type":"exact"}],"termid":"GO:1990085"}


id: PBO:0117156
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CCT5 antisense RNA 1","termid":"PBO:0117156"}


id: GO:0008982
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sugar(out) = protein histidine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.","definition_xrefs":["ISBN:0815340729","GOC:mtg_transport"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbohydrate transmembrane transporter activity","termid":"GO:0015144"},{"relation_name":"is_a","term_name":"phosphotransferase activity, alcohol group as acceptor","termid":"GO:0016773"},{"relation_name":"is_a","term_name":"active transmembrane transporter activity","termid":"GO:0022804"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0022857","GO:0016740","GO:0005215","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"protein-N(PI)-phosphohistidine-sugar phosphotransferase activity","secondary_identifiers":["TC:4.A","GO:0015455","GO:0015456"],"synonyms":[{"name":"PEP--sugar phosphotransferase enzyme II activity","type":"exact"},{"name":"PEP-dependent phosphotransferase enzyme II","type":"related"},{"name":"PTS permease activity","type":"related"},{"name":"PTS transporter","type":"related"},{"name":"enzyme II of the phosphotransferase system","type":"related"},{"name":"phosphoenolpyruvate-sugar phosphotransferase enzyme II","type":"related"},{"name":"phosphohistidinoprotein-hexose phosphotransferase activity","type":"related"},{"name":"phosphoprotein factor-hexose phosophotransferase activity","type":"related"},{"name":"phosphotransfer-driven group translocator","type":"broad"},{"name":"protein-Np-phosphohistidine-sugar phosphotransferase activity","type":"exact"}],"termid":"GO:0008982"}


id: GO:0044877
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id: PBO:0088682
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TRAPP III complex subunit Trs85b","termid":"PBO:0088682"}


id: GO:0002013
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process by a carbon dioxide stimulus is received and converted to a molecular signal by the vasomotor center of the central nervous system.","definition_xrefs":["ISBN:0721643949"],"direct_ancestors":[{"relation_name":"is_a","term_name":"detection of carbon dioxide","termid":"GO:0003031"},{"relation_name":"part_of","term_name":"regulation of systemic arterial blood pressure by ischemic conditions","termid":"GO:0001980"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"detection of carbon dioxide by vasomotor center","termid":"GO:0002013"}


id: MONDO:0013118
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Nijmegen breakage syndrome-like disorder is a rare, genetic multiple congenital anomalies/dysmorphic syndrome characterized by growth retardation, short stature, developmental delay, intellectual disability, craniofacial dysmorphism (i.e. severe microcephaly, sloping forehead, prominent eyes, broad nasal ridge, hypoplastic nasal septum, epicanthal folds), spontaneous chromosomal instability, cellular hypersensitivity to ionizing radiation and radioresistant DNA synthesis, without severe infections, immunodeficiency or cancer predisposition. Additional reported features include mild spasticity, slight and nonprogressive ataxia, hyperopia, multiple pigmented nevi, widely spaced nipples, and clinodactyly.","definition_xrefs":["Orphanet:240760"],"direct_ancestors":[{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome without intellectual disability","termid":"MONDO:0015161"},{"relation_name":"is_a","term_name":"developmental anomaly of metabolic origin","termid":"MONDO:0015327"},{"relation_name":"is_a","term_name":"DNA repair disease","termid":"MONDO:0021190"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0021190"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0021190","MONDO:0005066"],"is_obsolete":false,"name":"Nijmegen breakage syndrome-like disorder","secondary_identifiers":["MEDGEN:442700","OMIM:613078","UMLS:C2751318","SCTID:766753005","NCIT:C153178","MESH:C567767","GARD:17184","icd11.foundation:1014526672"],"synonyms":[{"name":"NBSLD","type":"exact"},{"name":"NBs-like disorder","type":"exact"},{"name":"Nijmegen breakage syndrome-like disorder","type":"exact"},{"name":"RAD50 deficiency","type":"exact"},{"name":"Rad50 deficiency","type":"related"},{"name":"microcephaly and chromosomal instability without immunodeficiency","type":"exact"},{"name":"microcephaly and spontaneous chromosome instability without immunodeficiency","type":"related"}],"termid":"MONDO:0013118","xrefs":{"Monarch":{"xref_id":"0013118"}}}


id: PBO:0058716
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 6844","termid":"PBO:0058716"}


id: PBO:0088469
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RSC complex bromodomain subunit Rsc4","termid":"PBO:0088469"}


id: MONDO:0002653
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A premalignant condition morphologically characterized by the presence of the characteristic Paget cells in the intraepithelial tissue of the penis. It presents as a smooth raised reddish area that may or may not be painful. -- 2003","definition_xrefs":["NCIT:C27817"],"direct_ancestors":[{"relation_name":"is_a","term_name":"penile carcinoma","termid":"MONDO:0006360"},{"relation_name":"is_a","term_name":"extramammary Paget disease","termid":"MONDO:0008177"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"Paget disease of the penis","secondary_identifiers":["GARD:21638","Orphanet:398053","SCTID:398768004","MEDGEN:66374","UMLS:C0221286","DOID:3448"],"synonyms":[{"name":"Paget disease of the penis","type":"exact"},{"name":"Paget's disease of penis","type":"exact"},{"name":"Paget's disease of the penis","type":"exact"},{"name":"adenocarcinoma of penis","type":"exact"},{"name":"adenocarcinoma of the penis","type":"related"},{"name":"penile adenocarcinoma","type":"exact"},{"name":"penis Paget disease","type":"exact"},{"name":"penis Paget's disease","type":"related"},{"name":"penis adenocarcinoma","type":"exact"},{"name":"penis mammary Paget's disease","type":"exact"}],"termid":"MONDO:0002653","xrefs":{"Monarch":{"xref_id":"0002653"}}}


id: GO:0000966
data:
  {"annotated_genes":["SJAG_04034","SJAG_00955","SJAG_02250","SJAG_04767","SJAG_01713","SJAG_04006","SJAG_02526","SJAG_01724","SJAG_04524","SJAG_06613","SJAG_03796","SJAG_01623","SJAG_04233","SJAG_04527","SJAG_03901","SJAG_00772","SJAG_04488","SJAG_04582","SJAG_04224","SJAG_00195"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[76777],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0036261"},{"annotations":[107247,77260,70225,74105],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006370"},{"annotations":[101692],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0106410"},{"annotations":[72104,79739,108572,74671],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000472"},{"annotations":[107009],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000465"},{"annotations":[113477],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000964"},{"annotations":[60386],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0106005"},{"annotations":[94892],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000967"},{"annotations":[61868],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0099116"},{"annotations":[59576,60957,81212,97985,72975,65509],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0001682"}]},"cv_name":"biological_process","definition":"Any process involved in forming the mature 5' end of an RNA molecule.","definition_xrefs":["GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA processing","termid":"GO:0006396"}],"gene_count":20,"genes_by_uniquename":{"SJAG_00195":null,"SJAG_00772":null,"SJAG_00955":null,"SJAG_01623":null,"SJAG_01713":null,"SJAG_01724":null,"SJAG_02250":null,"SJAG_02526":null,"SJAG_03796":null,"SJAG_03901":null,"SJAG_04006":null,"SJAG_04034":null,"SJAG_04224":null,"SJAG_04233":null,"SJAG_04488":null,"SJAG_04524":null,"SJAG_04527":null,"SJAG_04582":null,"SJAG_04767":null,"SJAG_06613":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"RNA 5'-end processing","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000104":null,"GO_REF:0000107":null,"GO_REF:0000108":null},"synonyms":[{"name":"RNA 5' end processing","type":"exact"}],"termid":"GO:0000966","terms_by_termid":{"GO:0000465":null,"GO:0000472":null,"GO:0000964":null,"GO:0000967":null,"GO:0001682":null,"GO:0006370":null,"GO:0036261":null,"GO:0099116":null,"GO:0106005":null,"GO:0106410":null}}


id: PBO:0042830
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"centrin 3","termid":"PBO:0042830"}


id: GO:0048654
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of the anther are generated and organized.","definition_xrefs":["GOC:sm","GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"floral organ morphogenesis","termid":"GO:0048444"},{"relation_name":"part_of","term_name":"stamen morphogenesis","termid":"GO:0048448"},{"relation_name":"part_of","term_name":"anther development","termid":"GO:0048653"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"anther morphogenesis","termid":"GO:0048654"}


id: MONDO:1011897
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"nervous system disorder, non-human animal","termid":"MONDO:1011336"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cavitating leukodystrophy, non-human animal","secondary_identifiers":["OMIA:002214"],"termid":"MONDO:1011897","xrefs":{"Monarch":{"xref_id":"1011897"}}}


id: PBO:0046240
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"elongin C pseudogene 34","termid":"PBO:0046240"}


id: GO:0008073
data:
  {"annotated_genes":["SJAG_04546"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[67046],"is_not":false,"summary":null,"term":"GO:0008073"}]},"cv_name":"molecular_function","definition":"Binds to and stops, prevents or reduces the activity of ornithine decarboxylase.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"enzyme inhibitor activity","termid":"GO:0004857"},{"relation_name":"is_a","term_name":"ornithine decarboxylase regulator activity","termid":"GO:0042979"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04546":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0004857"},{"rel_name":"is_a","termid":"GO:0030234"},{"rel_name":"is_a","termid":"GO:0140678"},{"rel_name":"is_a","termid":"GO:0098772"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0140678","GO:0098772","GO:0030234","GO:0004857","GO:0003674"],"is_obsolete":false,"name":"ornithine decarboxylase inhibitor activity","references_by_uniquename":{"GO_REF:0000002":null},"termid":"GO:0008073","terms_by_termid":{"GO:0008073":null}}


id: PBO:0040797
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"basic helix-loop-helix family member a15","termid":"PBO:0040797"}


id: GO:1905852
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of backward locomotion.","definition_xrefs":["GOC:TermGenie","PMID:11717360","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of locomotion","termid":"GO:0040017"},{"relation_name":"is_a","term_name":"regulation of backward locomotion","termid":"GO:0043058"},{"relation_name":"positively_regulates","term_name":"backward locomotion","termid":"GO:0043057"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of backward locomotion","synonyms":[{"name":"activation of backward locomotion","type":"narrow"},{"name":"up regulation of backward locomotion","type":"exact"},{"name":"up-regulation of backward locomotion","type":"exact"},{"name":"upregulation of backward locomotion","type":"exact"}],"termid":"GO:1905852"}


id: GO:0015468
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Plasmid-encoded bacteriocins which are produced by enteric bacteria. Exert a lethal effect on other bacteria including E. coli strains that lack the Col plasmid. Bind to a cell surface receptor and are transported into the periplasm via an energy-dependent process involving a TonB- or TolA-dependent hetero-oligomeric protein complex. Some colicins kill their target cell by inserting into the cytoplasmic membrane where they form voltage-sensitive (trans-negative) channels that depolarize and deenergize the cell, and thereby kill it.","definition_xrefs":["TC:1.C.1.-.-"],"gene_count":0,"genotype_count":0,"name":"obsolete colicin (obsolete GO:0015468)","synonyms":[{"name":"colicin","type":"exact"}],"termid":"GO:0015468"}


id: PBO:0086591
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative protein of unknown function; expression depends on Swi5p; GFP-fusion protein localizes to the endoplasmic reticulum; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO)","termid":"PBO:0086591"}


id: PR:O13907
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC22A12.16 gene.","definition_xrefs":["UniProtKB:O13907","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP-citrate synthase subunit 2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC22A12.16","synonyms":[{"name":"ATP-citrate (pro-S-)-lyase 2 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-SPAC22A12.16","type":"exact"},{"name":"citrate cleavage enzyme subunit 2 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O13907"}


id: GO:0019111
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: phenanthrol + X-SO3(-) = HX + phenanthrylsulfate.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete phenanthrol sulfotransferase activity (obsolete GO:0019111)","synonyms":[{"name":"phenanthrol sulphotransferase activity","type":"exact"}],"termid":"GO:0019111"}


id: PBO:0002778
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cryptic Loci Regulator","termid":"PBO:0002778"}


id: PBO:0056122
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lysosomal enzyme trafficking factor","termid":"PBO:0056122"}


id: PBO:0046043
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"eukaryotic translation initiation factor 3 subunit B","termid":"PBO:0046043"}


id: PBO:0068080
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 386","termid":"PBO:0068080"}


id: GO:0006354
data:
  {"annotated_genes":["SJAG_02416","SJAG_02070","SJAG_02873","SJAG_04670","SJAG_02319","SJAG_02653","SJAG_01213","SJAG_03481","SJAG_04038","SJAG_03118","SJAG_00914","SJAG_01765","SJAG_00119","SJAG_02101","SJAG_00731","SJAG_04353","SJAG_03211","SJAG_03956","SJAG_04933","SJAG_00293","SJAG_00925","SJAG_04257","SJAG_01149","SJAG_04106","SJAG_01610","SJAG_03128","SJAG_03144","SJAG_02314","SJAG_02057","SJAG_02871","SJAG_01313","SJAG_03944","SJAG_00139","SJAG_03967","SJAG_02097","SJAG_04261","SJAG_01444","SJAG_00540","SJAG_01562","SJAG_03578","SJAG_02393","SJAG_02691","SJAG_01713","SJAG_03006","SJAG_00320","SJAG_00483","SJAG_01128","SJAG_00913","SJAG_01151","SJAG_01698","SJAG_02698","SJAG_02238","SJAG_01707","SJAG_03061","SJAG_00150"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[80724],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0001193"},{"annotations":[117546],"is_not":false,"rel_names":["negatively_regulates","regulates"],"summary":null,"term":"GO:0034244"},{"annotations":[72016,81600],"is_not":false,"rel_names":["positively_regulates","regulates"],"summary":null,"term":"GO:0032786"},{"annotations":[79975,81336,65714,72847,116605,73259],"is_not":false,"rel_names":["regulates","positively_regulates"],"summary":null,"term":"GO:0032968"},{"annotations":[76302,91512,66131,113815,79272,62793,115130,69187,76954,104430,71858,65193,102869,65031,105341,94708,58367],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006362"},{"annotations":[113997,93424,91452,107446,113668,112775,106377,105049,107252,92121,94709,111062,98656,99449],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006368"},{"annotations":[92865,116510,110856,108349,115813,108344,89529,94098,113198,90713,103093,118475,114142,94977,91854],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0140673"}]},"cv_name":"biological_process","definition":"The extension of an RNA molecule after transcription initiation and promoter clearance at a DNA-dependent RNA polymerase promoter by the addition of ribonucleotides catalyzed by an RNA polymerase.","definition_xrefs":["PMID:18280161","GOC:mah","GOC:txnOH","PMID:15020047"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA biosynthetic process","termid":"GO:0032774"},{"relation_name":"part_of","term_name":"DNA-templated transcription","termid":"GO:0006351"}],"gene_count":55,"genes_by_uniquename":{"SJAG_00119":null,"SJAG_00139":null,"SJAG_00150":null,"SJAG_00293":null,"SJAG_00320":null,"SJAG_00483":null,"SJAG_00540":null,"SJAG_00731":null,"SJAG_00913":null,"SJAG_00914":null,"SJAG_00925":null,"SJAG_01128":null,"SJAG_01149":null,"SJAG_01151":null,"SJAG_01213":null,"SJAG_01313":null,"SJAG_01444":null,"SJAG_01562":null,"SJAG_01610":null,"SJAG_01698":null,"SJAG_01707":null,"SJAG_01713":null,"SJAG_01765":null,"SJAG_02057":null,"SJAG_02070":null,"SJAG_02097":null,"SJAG_02101":null,"SJAG_02238":null,"SJAG_02314":null,"SJAG_02319":null,"SJAG_02393":null,"SJAG_02416":null,"SJAG_02653":null,"SJAG_02691":null,"SJAG_02698":null,"SJAG_02871":null,"SJAG_02873":null,"SJAG_03006":null,"SJAG_03061":null,"SJAG_03118":null,"SJAG_03128":null,"SJAG_03144":null,"SJAG_03211":null,"SJAG_03481":null,"SJAG_03578":null,"SJAG_03944":null,"SJAG_03956":null,"SJAG_03967":null,"SJAG_04038":null,"SJAG_04106":null,"SJAG_04257":null,"SJAG_04261":null,"SJAG_04353":null,"SJAG_04670":null,"SJAG_04933":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0006351"},{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006351","GO:0008150","GO:0010467"],"is_obsolete":false,"name":"DNA-templated transcription elongation","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null,"GO_REF:0000117":null},"secondary_identifiers":["GO:0001124"],"synonyms":[{"name":"DNA-dependent transcription, elongation","type":"exact"},{"name":"DNA-templated transcription, elongation","type":"exact"},{"name":"RNA elongation","type":"broad"},{"name":"RNA elongation from bacterial-type RNA polymerase promoter","type":"narrow"},{"name":"transcription elongation from bacterial-type RNA polymerase promoter","type":"narrow"},{"name":"transcription elongation, DNA-dependent","type":"exact"},{"name":"transcriptional elongation, DNA-dependent","type":"exact"}],"termid":"GO:0006354","terms_by_termid":{"GO:0001193":null,"GO:0006362":null,"GO:0006368":null,"GO:0032786":null,"GO:0032968":null,"GO:0034244":null,"GO:0140673":null}}


id: SO:0000176
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A conserved hexamer about 35-bp upstream of the start point of bacterial transcription units; consensus=TTGACa or TGTTGACA. This region is associated with sigma factor 70.","direct_ancestors":[{"relation_name":"is_a","term_name":"DNA_motif","termid":"SO:0000713"},{"relation_name":"part_of","term_name":"bacterial_RNApol_promoter_sigma_70_element","termid":"SO:0001671"},{"relation_name":"part_of","term_name":"bacterial_RNApol_promoter_sigma_ecf_element","termid":"SO:0001913"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"minus_35_signal","synonyms":[{"name":"-35 signal","type":"exact"},{"name":"INSDC_feature:regulatory","type":"broad"},{"name":"INSDC_qualifier:minus_35_signal","type":"exact"},{"name":"minus 35 signal","type":"exact"}],"termid":"SO:0000176"}


id: PBO:0003072
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fructose-1,6-bisphosphatase Fbp1","termid":"PBO:0003072"}


id: PBO:0005031
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sulphate transporter (predicted)","termid":"PBO:0005031"}


id: PBO:0038767
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"actin related protein 5","termid":"PBO:0038767"}


id: PBO:0039259
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aldehyde dehydrogenase 7 family member A1 pseudogene 1","termid":"PBO:0039259"}


id: GO:0044808
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The appearance of oncostatin M due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.","definition_xrefs":["GOC:rv"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytokine production","termid":"GO:0001816"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"oncostatin M production","synonyms":[{"name":"OSM production","type":"exact"}],"termid":"GO:0044808"}


id: PBO:0060265
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MYG1 antisense RNA 1","termid":"PBO:0060265"}


id: PBO:0090097
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"t-UTP complex subunit Utp8","termid":"PBO:0090097"}


id: PBO:0028212
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-signal_transduction_phenotype","termid":"PBO:0028212"}


id: MONDO:0011009
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"muscular dystrophy, congenital, with severe central nervous system atrophy and absence of large myelinated fibers","secondary_identifiers":["UMLS:C1832665","MESH:C563378","OMIM:601170","MEDGEN:331338"],"synonyms":[{"name":"muscular dystrophy, congenital, with severe central nervous system atrophy and absence of large myelinated fibers","type":"exact"}],"termid":"MONDO:0011009","xrefs":{"Monarch":{"xref_id":"0011009"}}}


id: MOD:00853
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces a carboxamido group with a carboxyl group labeled with two (18)O.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"(18)O labeled deamidated residue","termid":"MOD:00851"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2x(18)O labeled deamidated residue","termid":"MOD:00853"}


id: PBO:0061805
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"outer dense fiber of sperm tails 3 like 1","termid":"PBO:0061805"}


id: PBO:0111815
data:
  {"annotation_feature_type":"gene","cv_name":"pombase_family_or_domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UBA domain protein","termid":"PBO:0111815"}


id: MONDO:0009816
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any autosomal recessive malignant osteopetrosis in which the cause of the disease is a mutation in the TNFSF11 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive osteopetrosis","termid":"MONDO:0019026"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328","MONDO:0006025"],"is_obsolete":false,"name":"autosomal recessive osteopetrosis 2","secondary_identifiers":["OMIM:259710","UMLS:C1850126","DOID:0110943","GARD:4157","MEDGEN:342420","MESH:C536059"],"synonyms":[{"name":"OPTB2","type":"exact"},{"name":"TNFSF11 autosomal recessive malignant osteopetrosis","type":"exact"},{"name":"TNFSF11 autosomal recessive osteopetrosis","type":"exact"},{"name":"TNFSF11-related osteopetrosis","type":"exact"},{"name":"autosomal recessive malignant osteopetrosis caused by mutation in TNFSF11","type":"exact"},{"name":"autosomal recessive osteopetrosis caused by mutation in TNFSF11","type":"exact"},{"name":"autosomal recessive osteopetrosis type 2","type":"exact"},{"name":"mild autosomal recessive form osteopetrosis","type":"exact"},{"name":"osteoclast-poor osteopetrosis","type":"exact"},{"name":"osteopetrosis autosomal recessive 2","type":"related"},{"name":"osteopetrosis osteoclast-poor","type":"related"},{"name":"osteopetrosis, autosomal recessive 2","type":"related"},{"name":"osteopetrosis, autosomal recessive type 2","type":"exact"},{"name":"osteopetrosis, mild autosomal recessive form","type":"related"},{"name":"osteopetrosis, osteoclast-poor","type":"related"}],"termid":"MONDO:0009816","xrefs":{"Monarch":{"xref_id":"0009816"}}}


id: PBO:0068650
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U4 small nuclear 31, pseudogene","termid":"PBO:0068650"}


id: PBO:0046548
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"endogenous retrovirus group H member 2","termid":"PBO:0046548"}


id: MONDO:0009812
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete osteomalacia, sclerosing, with cerebral calcification (obsolete MONDO:0009812)","termid":"MONDO:0009812","xrefs":{"Monarch":{"xref_id":"0009812"}}}


id: GO:0032871
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of nucleus organization","termid":"GO:1903353"},{"relation_name":"regulates","term_name":"karyogamy","termid":"GO:0000741"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of karyogamy","termid":"GO:0032871"}


id: GO:0051282
data:
  {"annotated_genes":["SJAG_03850"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[108232],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061454"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of localization","termid":"GO:0032879"},{"relation_name":"is_a","term_name":"regulation of cellular process","termid":"GO:0050794"},{"relation_name":"regulates","term_name":"sequestering of calcium ion","termid":"GO:0051208"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03850":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of sequestering of calcium ion","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"regulation of calcium ion (Ca2+) retention","type":"exact"},{"name":"regulation of calcium ion (Ca2+) sequestering","type":"exact"},{"name":"regulation of calcium ion (Ca2+) sequestration","type":"exact"},{"name":"regulation of calcium ion (Ca2+) storage","type":"exact"},{"name":"regulation of retention of calcium ion (Ca2+)","type":"exact"},{"name":"regulation of sequestering of calcium ion (Ca2+)","type":"exact"},{"name":"regulation of sequestration of calcium ion (Ca2+)","type":"exact"},{"name":"regulation of storage of calcium ion (Ca2+)","type":"exact"}],"termid":"GO:0051282","terms_by_termid":{"GO:0061454":null}}


id: PBO:0050051
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"major histocompatibility complex, class I, P (pseudogene)","termid":"PBO:0050051"}


id: PBO:0005716
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"riboflavin kinase Fmn1","termid":"PBO:0005716"}


id: FYPO:0005548
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular response to brefeldin A.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased protein phosphorylation during vegetative growth","termid":"FYPO:0001038"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0002494","FYPO:0002274","FYPO:0000002","FYPO:0001985","FYPO:0005447"],"is_obsolete":false,"name":"increased protein phosphorylation during cellular response to brefeldin A","synonyms":[{"name":"increased protein phosphorylation during cellular response to brefeldin A during mitotic cell cycle","type":"related"},{"name":"increased protein phosphorylation during cellular response to brefeldin A during vegetative growth","type":"exact"}],"termid":"FYPO:0005548"}


id: GO:0035985
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A transcriptionally-silent heterochromatin structure present in senescent cells. Contains the condensed chromatin of one chromosome and is enriched for histone modifications. Thought to repress expression of proliferation-promoting genes.","definition_xrefs":["PMID:21248468","PMID:15621527","GOC:yaf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"heterochromatin","termid":"GO:0000792"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005694"}],"interesting_parent_ids":["GO:0005694","GO:0005575"],"is_obsolete":false,"name":"senescence-associated heterochromatin focus","synonyms":[{"name":"SAHF","type":"exact"},{"name":"senescence-associated heterochromatin foci","type":"exact"}],"termid":"GO:0035985"}


id: PATO:0002417
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"Extending through or affecting the entire thickness of the wall of an organ or cavity or boundary.","definition_xrefs":["PATOC:MPATH"],"direct_ancestors":[{"relation_name":"is_a","term_name":"position","termid":"PATO:0000140"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmural","termid":"PATO:0002417"}


id: GO:0140132
data:
  {"annotated_genes":["SJAG_00532"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[92442],"is_not":false,"summary":null,"term":"GO:0140132"}]},"cv_name":"molecular_function","definition":"Binding to an iron-sulfur cluster and delivering it to an acceptor molecule.","definition_xrefs":["PMID:29051382","PMID:22966982"],"direct_ancestors":[{"relation_name":"is_a","term_name":"metallochaperone activity","termid":"GO:0016530"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00532":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140104"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0140104","GO:0003674"],"is_obsolete":false,"name":"iron-sulfur cluster chaperone activity","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"iron-sulfur cluster carrier activity","type":"exact"}],"termid":"GO:0140132","terms_by_termid":{"GO:0140132":null}}


id: PBO:0077768
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TOMM22 pseudogene 4","termid":"PBO:0077768"}


id: PBO:0081648
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 573","termid":"PBO:0081648"}


id: GO:0044754
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A type of secondary lysosome in which a primary lysosome has fused with the outer membrane of an autophagosome or amphisome. It is involved in the second step of autophagy in which it degrades contents with acidic lysosomal hydrolases.","definition_xrefs":["GOC:sart","PMID:24657946","PMID:19008921","NIF_Subcellular:sao8444068431"],"direct_ancestors":[{"relation_name":"is_a","term_name":"secondary lysosome","termid":"GO:0005767"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0005773"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0005737","GO:0005773","GO:0005575"],"is_obsolete":false,"name":"autolysosome","synonyms":[{"name":"AVd","type":"exact"},{"name":"degrading autophagic vacuole","type":"exact"}],"termid":"GO:0044754"}


id: PBO:0059571
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"metallothionein 1 pseudogene 3","termid":"PBO:0059571"}


id: GO:0061318
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.","definition_xrefs":["GOC:dph","GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell differentiation","termid":"GO:0030154"},{"relation_name":"part_of","term_name":"renal system development","termid":"GO:0072001"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"renal filtration cell differentiation","termid":"GO:0061318"}


id: MONDO:0044699
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"is_a","term_name":"congenital nervous system disorder","termid":"MONDO:0002320"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"},{"relation_name":"is_a","term_name":"autosomal dominant syndromic intellectual disability","termid":"MONDO:0100601"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"},{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0002320","MONDO:0000426"],"is_obsolete":false,"name":"SIN3A-related intellectual disability syndrome","secondary_identifiers":["GARD:22043","Orphanet:500163"],"termid":"MONDO:0044699","xrefs":{"Monarch":{"xref_id":"0044699"}}}


id: PBO:0057653
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 1245b","termid":"PBO:0057653"}


id: PBO:0040417
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATPase H+ transporting V0 subunit c pseudogene 2","termid":"PBO:0040417"}


id: PBO:0028768
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_nuclear_polyadenylated_mRNA_level_during_vegetative_growth","termid":"PBO:0028768"}


id: GO:0051992
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine = di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP.","definition_xrefs":["RHEA:28386"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphotransferase activity, for other substituted phosphate groups","termid":"GO:0016780"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016780"}],"interesting_parent_ids":["GO:0003824","GO:0016740","GO:0003674","GO:0016780"],"is_obsolete":false,"name":"UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity","secondary_identifiers":["MetaCyc:PHOSNACMURPENTATRANS-RXN"],"termid":"GO:0051992"}


id: GO:0060196
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.","definition_xrefs":["GOC:tb","PMID:18075583","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of DNA-templated transcription","termid":"GO:0045893"},{"relation_name":"is_a","term_name":"regulation of antisense RNA transcription","termid":"GO:0060194"},{"relation_name":"positively_regulates","term_name":"antisense RNA transcription","termid":"GO:0009300"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006351"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006355"},{"rel_name":"positively_regulates","termid":"GO:0006351"},{"rel_name":"regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0006355","GO:0006351","GO:0008150","GO:0010467"],"is_obsolete":false,"name":"positive regulation of antisense RNA transcription","termid":"GO:0060196"}


id: MONDO:0021166
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A disease involving a pathogenic inflammatory response in the anatomical structure.","definition_xrefs":["MONDO:patterns/inflammatory_disease_by_site"],"direct_ancestors":[{"relation_name":"is_a","term_name":"human disease","termid":"MONDO:0700096"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"inflammatory disease","secondary_identifiers":["UMLS:C1290884","NCIT:C93210","ICD9:799.89","SCTID:128139000","MEDGEN:452939"],"synonyms":[{"name":"anatomical structure inflammation","type":"exact"},{"name":"inflammation of anatomical structure","type":"exact"},{"name":"inflammatory disease","type":"exact"},{"name":"inflammatory disorder","type":"exact"}],"termid":"MONDO:0021166","xrefs":{"Monarch":{"xref_id":"0021166"}}}


id: PBO:0082418
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Bifunctional HMG aldolase/oxaloacetate decarboxylase; requires divalent metal ions for activity; competitively inhibited by oxalate; forms a ring-shaped homotrimer; similar to members of the prokaryotic RraA family of class II (divalent metal ion dependent) pyruvate aldolases from the meta cleavage pathways of protocatechuate and gallate","termid":"PBO:0082418"}


id: FYPO:0003342
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which a cell contains more than one nucleus, is longer than normal, and has a greater length:diameter ratio than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"multinucleate","termid":"FYPO:0003341"},{"relation_name":"is_a","term_name":"increased cell length","termid":"FYPO:0006633"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000005"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001985","FYPO:0000005"],"is_obsolete":false,"name":"elongated multinucleate cell","synonyms":[{"name":"long multinucleate cell","type":"exact"}],"termid":"FYPO:0003342"}


id: PBO:0075836
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"somatostatin receptor 4","termid":"PBO:0075836"}


id: MONDO:0100463
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An autosomal recessive inborn disorder of cobalamin metabolism caused by biallelic variants in MMADHC. Depending on the type and location of variants in MMADHC, patients may present with methylmalonic aciduria, homocystinuria, or both. MMADHC has been reported to result in the cblD complementation group of cobalamin disorders.","direct_ancestors":[{"relation_name":"is_a","term_name":"inborn disorder of cobalamin metabolism and transport","termid":"MONDO:0019220"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066"],"is_obsolete":false,"name":"methylmalonic aciduria and/or homocystinuria, cblD type","termid":"MONDO:0100463","xrefs":{"Monarch":{"xref_id":"0100463"}}}


id: MONDO:0021380
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A neoplasm (disease) that involves the myocardium.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"heart neoplasm","termid":"MONDO:0021209"},{"relation_name":"is_a","term_name":"myocardial disorder","termid":"MONDO:0024643"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"neoplasm of myocardium","secondary_identifiers":["MEDGEN:266216","NCIT:C5349","SCTID:126732009","UMLS:C1290402","ICD9:239.89"],"synonyms":[{"name":"myocardial neoplasm","type":"exact"},{"name":"myocardial tumor","type":"exact"},{"name":"myocardial tumour","type":"exact"},{"name":"myocardium neoplasm","type":"exact"},{"name":"myocardium neoplasm (disease)","type":"exact"},{"name":"myocardium tumor","type":"exact"},{"name":"myocardium tumour","type":"exact"},{"name":"neoplasm of myocardium","type":"exact"},{"name":"neoplasm of the myocardium","type":"exact"},{"name":"tumor of myocardium","type":"exact"},{"name":"tumor of the myocardium","type":"exact"},{"name":"tumour of myocardium","type":"exact"},{"name":"tumour of the myocardium","type":"exact"}],"termid":"MONDO:0021380","xrefs":{"Monarch":{"xref_id":"0021380"}}}


id: GO:1901125
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving candicidin.","definition_xrefs":["GOC:TermGenie","UniPathway:UPA00101","GOC:yaf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"metabolic process","termid":"GO:0008152"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"candicidin metabolic process","synonyms":[{"name":"candicidin metabolism","type":"exact"}],"termid":"GO:1901125"}


id: PBO:0091464
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ChiTinaSe 2","termid":"PBO:0091464"}


id: GO:0015133
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of uronic acid from one side of a membrane to the other. Uronic acids are any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monocarboxylic acid transmembrane transporter activity","termid":"GO:0008028"},{"relation_name":"is_a","term_name":"monosaccharide transmembrane transporter activity","termid":"GO:0015145"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0022857","GO:0005215","GO:0003674"],"is_obsolete":false,"name":"uronic acid transmembrane transporter activity","termid":"GO:0015133"}


id: PBO:0090080
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase Alg13","termid":"PBO:0090080"}


id: GO:0051516
data:
  {"annotated_genes":["SJAG_03581","SJAG_02392","SJAG_00514","SJAG_02169","SJAG_00244"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[114649],"is_not":false,"summary":null,"term":"GO:0051516"},{"annotations":[94066,95341,89328],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051519"},{"annotations":[90191],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051517"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of unidimensional cell growth","termid":"GO:0051510"},{"relation_name":"regulates","term_name":"bipolar cell growth","termid":"GO:0042815"}],"gene_count":5,"genes_by_uniquename":{"SJAG_00244":null,"SJAG_00514":null,"SJAG_02169":null,"SJAG_02392":null,"SJAG_03581":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of bipolar cell growth","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0051516","terms_by_termid":{"GO:0051516":null,"GO:0051517":null,"GO:0051519":null}}


id: PBO:0078908
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Gln (anticodon CTG) 17-1","termid":"PBO:0078908"}


id: MONDO:0012899
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"alopecia, isolated","termid":"MONDO:0000005"},{"relation_name":"is_a","term_name":"androgenetic alopecia","termid":"MONDO:0005339"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"alopecia, androgenetic, 3","secondary_identifiers":["MESH:C567317","UMLS:C2676272","MEDGEN:382808","OMIM:612421"],"synonyms":[{"name":"AGA3","type":"exact"},{"name":"alopecia, androgenetic, 3","type":"exact"}],"termid":"MONDO:0012899","xrefs":{"Monarch":{"xref_id":"0012899"}}}


id: PBO:0031592
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_initiation_of_premeiotic_DNA_replication","termid":"PBO:0031592"}


id: PBO:0091450
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"was previously incorrectly named as mtx1 with MTX1 human ortholog","termid":"PBO:0091450"}


id: PBO:0050331
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heterogeneous nuclear ribonucleoprotein A1 pseudogene 33","termid":"PBO:0050331"}


id: GO:1902436
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of male mating behavior.","definition_xrefs":["GOC:TermGenie","PMID:24089208"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of behavior","termid":"GO:0048521"},{"relation_name":"is_a","term_name":"regulation of male mating behavior","termid":"GO:1902435"},{"relation_name":"is_a","term_name":"negative regulation of reproductive process","termid":"GO:2000242"},{"relation_name":"negatively_regulates","term_name":"male mating behavior","termid":"GO:0060179"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of male mating behavior","synonyms":[{"name":"down regulation of male mating behavior","type":"exact"},{"name":"down-regulation of male mating behavior","type":"exact"},{"name":"downregulation of male mating behavior","type":"exact"},{"name":"inhibition of male mating behavior","type":"narrow"}],"termid":"GO:1902436"}


id: PBO:0083076
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dipeptidyl aminopeptidase; Golgi integral membrane protein that cleaves on the carboxyl side of repeating -X-Ala- sequences, required for maturation of alpha factor, transcription is induced by a-factor","termid":"PBO:0083076"}


id: MONDO:0008489
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sternum, premature obliteration of sutures of","secondary_identifiers":["OMIM:184800","UMLS:C1861485","MEDGEN:396144"],"synonyms":[{"name":"sternum, premature obliteration of sutures of","type":"exact"}],"termid":"MONDO:0008489","xrefs":{"Monarch":{"xref_id":"0008489"}}}


id: FYPO:0002021
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patches are localized throughout the cell cortex (rather than concentrated at the cell ends as in wild type cells).","definition_xrefs":["PMID:8834798","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mislocalized actin cortical patches during vegetative growth","termid":"FYPO:0003988"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0004803"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0000138"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0004803","FYPO:0005447","FYPO:0001985","FYPO:0000138","FYPO:0000002"],"is_obsolete":false,"name":"dispersed actin cortical patch localization during vegetative growth","synonyms":[{"name":"delocalised actin cortical patches during vegetative growth","type":"exact"},{"name":"delocalized actin cortical patches during vegetative growth","type":"exact"},{"name":"depolarized actin cortical patch localization during vegetative growth","type":"exact"},{"name":"dispersed F-actin patch localization during vegetative growth","type":"exact"},{"name":"dispersed actin cortical patch localisation during vegetative growth","type":"exact"},{"name":"dispersed actin cortical patch localization during mitotic cell cycle","type":"related"},{"name":"dispersed actin cortical patch location during vegetative growth","type":"related"},{"name":"dispersed actin patch localization during vegetative growth","type":"exact"}],"termid":"FYPO:0002021"}


id: GO:0009595
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of events in which a biotic stimulus, one caused or produced by a living organism, is received and converted into a molecular signal.","definition_xrefs":["GOC:hb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to biotic stimulus","termid":"GO:0009607"},{"relation_name":"is_a","term_name":"detection of stimulus","termid":"GO:0051606"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"detection of biotic stimulus","secondary_identifiers":["GO:0009596"],"synonyms":[{"name":"perception of biotic stimulus","type":"related"}],"termid":"GO:0009595"}


id: PBO:0042140
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CCL3 antisense RNA 1","termid":"PBO:0042140"}


id: GO:0004089
data:
  {"annotated_genes":["SJAG_06611"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[79333],"is_not":false,"summary":null,"term":"GO:0004089"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: hydrogencarbonate + H+ = CO2 + H2O.","definition_xrefs":["EC:4.2.1.1"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydro-lyase activity","termid":"GO:0016836"}],"gene_count":1,"genes_by_uniquename":{"SJAG_06611":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016829"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016829"],"is_obsolete":false,"name":"carbonate dehydratase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["Reactome:R-HSA-1475017","Reactome:R-HSA-1237045","Reactome:R-HSA-1475022","Reactome:R-HSA-1475435","Reactome:R-HSA-1475436","MetaCyc:RXN0-5224","Reactome:R-HSA-1237059","Reactome:R-HSA-1475025","Reactome:R-HSA-1237047","Reactome:R-HSA-1475032","Reactome:R-HSA-1475026","Reactome:R-HSA-1475028","RHEA:10748","Reactome:R-HSA-1237081"],"synonyms":[{"name":"anhydrase activity","type":"related"},{"name":"carbonate anhydrase activity","type":"related"},{"name":"carbonate hydro-lyase (carbon-dioxide-forming)","type":"related"},{"name":"carbonate hydro-lyase activity","type":"related"},{"name":"carbonic acid anhydrase activity","type":"related"},{"name":"carbonic anhydrase A","type":"related"},{"name":"carbonic anhydrase activity","type":"exact"},{"name":"carbonic dehydratase activity","type":"related"},{"name":"carboxyanhydrase activity","type":"related"}],"termid":"GO:0004089","terms_by_termid":{"GO:0004089":null}}


id: MONDO:0014870
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"NEK9-related lethal skeletal dysplasia is a rare, lethal, primary bone dysplasia characterized by fetal akinesia, multiple contractures, shortening of all long bones, short, broad ribs, narrow chest and thorax, pulmonary hypoplasia and a protruding abdomen. Short bowed femurs may also be associated.","definition_xrefs":["Orphanet:464366"],"direct_ancestors":[{"relation_name":"is_a","term_name":"thoracic malformation","termid":"MONDO:0015929"},{"relation_name":"is_a","term_name":"lethal congenital contracture syndrome","termid":"MONDO:0017436"},{"relation_name":"is_a","term_name":"short rib dysplasia","termid":"MONDO:0019691"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NEK9-related lethal skeletal dysplasia","secondary_identifiers":["OMIM:617022","MEDGEN:1799564","GARD:17818","UMLS:C5568141"],"synonyms":[{"name":"LCCS10","type":"exact"},{"name":"lethal congenital contracture syndrome 10","type":"exact"},{"name":"lethal congenital contracture syndrome type 10","type":"exact"},{"name":"lethal skeletal dysplasia-fetal akinesia-contractures-thoracic dysplasia-pulmonary hypoplasia syndrome","type":"exact"}],"termid":"MONDO:0014870","xrefs":{"Monarch":{"xref_id":"0014870"}}}


id: PBO:0074590
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, H/ACA box 5B","termid":"PBO:0074590"}


id: FYPO:0004908
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which L-aminoadipate-semialdehyde dehydrogenase activity is absent.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished catalytic activity","termid":"FYPO:0000664"},{"relation_name":"is_a","term_name":"abnormal L-aminoadipate-semialdehyde dehydrogenase activity","termid":"FYPO:0001674"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000707"}],"interesting_parent_ids":["FYPO:0000654","FYPO:0000661","FYPO:0000652","FYPO:0000707","FYPO:0001985"],"is_obsolete":false,"name":"abolished L-aminoadipate-semialdehyde dehydrogenase activity","synonyms":[{"name":"L-aminoadipate-semialdehyde dehydrogenase activity abolished","type":"exact"},{"name":"abolished alpha-aminoadipate reductase activity","type":"exact"}],"termid":"FYPO:0004908"}


id: MONDO:0000518
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A chordoma (disease) that involves the fused sacrum.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vertebral column disorder","termid":"MONDO:0000812"},{"relation_name":"is_a","term_name":"spinal chordoma","termid":"MONDO:0002894"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sacrum chordoma","secondary_identifiers":["MEDGEN:756688","DOID:0050900","UMLS:C3164279","SCTID:447730004","NCIT:C129927"],"synonyms":[{"name":"chordoma (disease) of fused sacrum","type":"exact"},{"name":"fused sacrum chordoma (disease)","type":"exact"}],"termid":"MONDO:0000518","xrefs":{"Monarch":{"xref_id":"0000518"}}}


id: MONDO:0016275
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete adenocarcinoma of cervix uteri (obsolete MONDO:0016275)","termid":"MONDO:0016275","xrefs":{"Monarch":{"xref_id":"0016275"}}}


id: PBO:0040119
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ankyrin repeat and SOCS box containing 6","termid":"PBO:0040119"}


id: MONDO:0017269
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"X-linked form of inherited ichthyosis syndromic form.","definition_xrefs":["MONDO:patterns/x_linked"],"direct_ancestors":[{"relation_name":"is_a","term_name":"integumentary system disorder","termid":"MONDO:0002051"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"X-linked ichthyosis syndrome","secondary_identifiers":["MedDRA:10048063","GARD:21109","Orphanet:281210"],"synonyms":[{"name":"X-linked inherited ichthyosis syndromic form","type":"exact"},{"name":"inherited ichthyosis syndromic form, X-linked","type":"exact"}],"termid":"MONDO:0017269","xrefs":{"Monarch":{"xref_id":"0017269"}}}


id: PBO:0030193
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-elongated_multinucleate_aseptate_vegetative_cell","termid":"PBO:0030193"}


id: PBO:0000665
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/threonine protein kinase Gsk3","termid":"PBO:0000665"}


id: PBO:0055171
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2595","termid":"PBO:0055171"}


id: GO:0018278
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The deamination of N-terminal peptidyl-threonine to form peptidyl-2-oxobutanoic acid.","definition_xrefs":["RESID:AA0129"],"gene_count":0,"genotype_count":0,"name":"obsolete N-terminal peptidyl-threonine deamination (obsolete GO:0018278)","termid":"GO:0018278"}


id: GO:0046905
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2 geranylgeranyl diphosphate = 15-cis-phytoene + 2 diphosphate.","definition_xrefs":["RHEA:34475","PMID:12641468"],"direct_ancestors":[{"relation_name":"is_a","term_name":"prenyltransferase activity","termid":"GO:0004659"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016765"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016765","GO:0016740","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"15-cis-phytoene synthase activity","secondary_identifiers":["EC:2.5.1.32","MetaCyc:RXN-13323"],"synonyms":[{"name":"PSase activity","type":"exact"},{"name":"geranylgeranyl-diphosphate geranylgeranyltransferase activity","type":"exact"},{"name":"geranylgeranyl-diphosphate:geranylgeranyl-diphosphate geranylgeranyltransferase (15-cis-phytoene-forming) activity","type":"exact"},{"name":"phytoene synthase activity","type":"exact"},{"name":"prephytoene-diphosphate synthase activity","type":"exact"}],"termid":"GO:0046905"}


id: GO:0045045
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The pathway along which proteins and other substances are moved around and out of the cell. After synthesis on the ribosomes of the endoplasmic reticulum (ER), completed polypeptide chains are moved to the Golgi complex and subsequently sorted to various destinations. Proteins synthesized and sorted in the secretory pathway include not only those that are secreted from the cell but also enzymes and other resident proteins in the lumen of the ER, Golgi, and lysosomes as well as integral proteins in the membranes of these organelles and the plasma membrane.","definition_xrefs":["ISBN:0716731363"],"gene_count":0,"genotype_count":0,"name":"obsolete secretory pathway (obsolete GO:0045045)","synonyms":[{"name":"secretory pathway","type":"exact"}],"termid":"GO:0045045"}


id: PBO:0070113
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U7 small nuclear 27 pseudogene","termid":"PBO:0070113"}


id: MONDO:0007816
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete immune suppression (obsolete MONDO:0007816)","secondary_identifiers":["OMIM:146850"],"synonyms":[{"name":"IS","type":"related"},{"name":"Iscw","type":"related"},{"name":"immune suppression","type":"exact"},{"name":"streptococcal cell wall antigen, suppression of immune response to","type":"related"}],"termid":"MONDO:0007816","xrefs":{"Monarch":{"xref_id":"0007816"}}}


id: FYPO:0006120
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to actin cortical patches is decreased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein localization to actin cortical patch","termid":"FYPO:0000742"},{"relation_name":"is_a","term_name":"decreased protein localization to cell cortex during vegetative growth","termid":"FYPO:0000929"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000138"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0001320","FYPO:0005447","FYPO:0000138"],"is_obsolete":false,"name":"decreased protein localization to actin cortical patch","synonyms":[{"name":"decreased protein localisation to actin cortical patch during vegetative growth","type":"exact"},{"name":"decreased protein localization to actin cortical patch during mitotic cell cycle","type":"related"},{"name":"decreased protein localization to actin cortical patch during vegetative growth","type":"exact"},{"name":"decreased protein localization to actin patch","type":"exact"},{"name":"reduced protein localization to actin cortical patch during vegetative growth","type":"exact"}],"termid":"FYPO:0006120"}


id: PBO:0068476
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U1 small nuclear 55, pseudogene","termid":"PBO:0068476"}


id: PBO:0001925
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"medial ring protein Alm1","termid":"PBO:0001925"}


id: PBO:0034431
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-T-shaped_cell_during_G0_to_G1_transition","termid":"PBO:0034431"}


id: MONDO:0024330
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Inflammation of the anatomical structures of the middle ear secondary to an infectious process. Bacterial etiology is most common, but both viral and fungal pathogens are also possible. Symptoms include erythema and edema of the tympanic membrane, pain, and possibly fever. In severe infections, inflammation and edema of the structures of the middle ear can lead to perforation of the tympanic membrane secondary to the buildup of pressure in the narrow space.","definition_xrefs":["NCIT:C84354"],"direct_ancestors":[{"relation_name":"is_a","term_name":"otitis media","termid":"MONDO:0005441"},{"relation_name":"is_a","term_name":"ear infection","termid":"MONDO:0021666"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"infectious otitis media","secondary_identifiers":["UMLS:C2827407","MEDGEN:443472"],"synonyms":[{"name":"AOM","type":"exact"},{"name":"acute otitis Media","type":"exact"},{"name":"infectious otitis Media","type":"exact"},{"name":"middle Ear infection","type":"exact"},{"name":"otitis media","type":"broad"}],"termid":"MONDO:0024330","xrefs":{"Monarch":{"xref_id":"0024330"}}}


id: PR:P29458
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A DNA replication licensing factor MCM4 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR11630:SF45","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA replication licensing factor mcm4 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC16A11.17","secondary_identifiers":["UniProtKB:P29458"],"synonyms":[{"name":"SPCC16A11.17","type":"related"},{"name":"Spom972h-MCM4","type":"exact"},{"name":"cdc21","type":"related"},{"name":"cell division control protein 21 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"minichromosome maintenance protein 4 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:P29458"}


id: PBO:0109278
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 3113","termid":"PBO:0109278"}


id: PBO:0017945
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"actin binding methyltransferase Abp140 (predicted)","termid":"PBO:0017945"}


id: RO:0002457
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","direct_ancestors":[{"relation_name":"is_a","term_name":"trophically_interacts_with","termid":"RO:0002438"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acquires_nutrients_from","termid":"RO:0002457"}


id: PR:O94487
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mug27 gene.","definition_xrefs":["UniProtKB:O94487","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/threonine-protein kinase ppk35 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC417.06c","synonyms":[{"name":"Spom972h-mug27","type":"exact"},{"name":"meiotically up-regulated gene 27 protein (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O94487"}


id: PBO:0029072
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_protein_localization_to_nucleus,_with_protein_mislocalized_to_cytoplasm","termid":"PBO:0029072"}


id: PBO:0038702
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ACTB pseudogene 15","termid":"PBO:0038702"}


id: FYPO:0004598
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is increased during G2 phase of the mitotic cell cycle.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased protein localization to chromatin during vegetative growth","termid":"FYPO:0003011"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0005447","FYPO:0001320","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"increased protein localization to chromatin during mitotic G2 phase","synonyms":[{"name":"increased protein localisation to chromatin during mitotic G2 phase","type":"exact"},{"name":"increased protein localization to chromatin during mitotic G2 phase during vegetative growth","type":"exact"}],"termid":"FYPO:0004598"}


id: PR:O94305
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mgl1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O94305"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"monoglyceride lipase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC5E4.05c","synonyms":[{"name":"MAG hydrolase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"MAG lipase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"MAGL (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"MGH (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"MGL (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-mgl1","type":"exact"},{"name":"monoacylglycerol hydrolase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"monoacylglycerol lipase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O94305"}


id: MONDO:0010089
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"encephalopathy due to sulfite oxidase deficiency","termid":"MONDO:0019358"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0005328"],"is_obsolete":false,"name":"isolated sulfite oxidase deficiency","secondary_identifiers":["MESH:C538141","OMIM:272300","NANDO:2200583","Orphanet:99731","GARD:5062","SCTID:367368009","UMLS:C0268624","DOID:0111270","icd11.foundation:963607692","MEDGEN:78695"],"synonyms":[{"name":"ISOD","type":"exact"},{"name":"Sulfocysteinuria","type":"exact"},{"name":"isolated sulfite oxidase deficiency","type":"exact"},{"name":"sulfite oxidase deficiency","type":"exact"},{"name":"sulfite oxidase deficiency, isolated","type":"exact"},{"name":"sulfocysteinuria","type":"exact"}],"termid":"MONDO:0010089","xrefs":{"Monarch":{"xref_id":"0010089"}}}


id: GO:0043309
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of eosinophil degranulation.","definition_xrefs":["ISBN:0781735149"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of myeloid leukocyte mediated immunity","termid":"GO:0002886"},{"relation_name":"is_a","term_name":"regulation of leukocyte degranulation","termid":"GO:0043300"},{"relation_name":"is_a","term_name":"regulation of immune response","termid":"GO:0050776"},{"relation_name":"regulates","term_name":"eosinophil degranulation","termid":"GO:0043308"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0016192"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0008150","GO:0016192"],"is_obsolete":false,"name":"regulation of eosinophil degranulation","synonyms":[{"name":"regulation of eosinophil granule exocytosis","type":"exact"}],"termid":"GO:0043309"}


id: FYPO:0000683
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A regulation phenotype in which the basal activity of an enzyme is increased relative to normal. Basal enzyme activity is the activity observed in the absence of a regulator. Abnormally elevated basal activity may or may not reach the levels observed in the normal activated state.","definition_xrefs":["PomBase:al","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"catalytic activity phenotype","termid":"FYPO:0000654"},{"relation_name":"output_of","term_name":"abnormal regulation of catalytic activity","termid":"FYPO:0004916"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000652","FYPO:0000654","FYPO:0005447","FYPO:0001985"],"is_obsolete":false,"name":"constitutive catalytic activity","synonyms":[{"name":"constitutive catalytic activity during mitotic cell cycle","type":"related"},{"name":"constitutive catalytic activity during vegetative growth","type":"exact"},{"name":"constitutive enzymatic activity","type":"exact"},{"name":"constitutively active enzyme","type":"related"}],"termid":"FYPO:0000683"}


id: PBO:0047852
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fragile site, aphidicolin type, common, fra(1)(p21.2)","termid":"PBO:0047852"}


id: MONDO:1012117
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"congenital hypomyelinogenesis, non-human animal","termid":"MONDO:1011845"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"congenital hypomyelinogenesis, sheep","secondary_identifiers":["OMIA:000527-9940"],"termid":"MONDO:1012117","xrefs":{"Monarch":{"xref_id":"1012117"}}}


id: PBO:0111857
data:
  {"annotation_feature_type":"gene","cv_name":"pombase_family_or_domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SIN3 family co-repressor","termid":"PBO:0111857"}


id: MONDO:0008374
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"cone dystrophy","termid":"MONDO:0000455"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"retinal cone dystrophy type 1","secondary_identifiers":["MESH:C566719","UMLS:C1867326","OMIM:180020","GARD:3196","DOID:0081024","MEDGEN:356747"],"synonyms":[{"name":"RCD1","type":"related"},{"name":"cone dystrophy autosomal dominant","type":"related"},{"name":"cone dystrophy, autosomal dominant","type":"related"},{"name":"retinal cone Degeneration","type":"related"},{"name":"retinal cone dystrophy 1","type":"related"},{"name":"retinal cone dystrophy-1","type":"exact"}],"termid":"MONDO:0008374","xrefs":{"Monarch":{"xref_id":"0008374"}}}


id: PBO:0075922
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ST13, Hsp70 interacting protein pseudogene 14","termid":"PBO:0075922"}


id: PBO:0084867
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial ribosomal protein of the small subunit; has similarity to E. coli S10 ribosomal protein; essential for viability, unlike most other mitoribosomal proteins","termid":"PBO:0084867"}


id: GO:0160097
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle, is driven by ATP hydrolysis.","definition_xrefs":["PMID:25013168"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA topoisomerase activity","termid":"GO:0003916"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140097"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016853"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0140097","GO:0016853","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"reverse gyrase activity","secondary_identifiers":["WIKIPEDIA:Reverse_gyrase"],"termid":"GO:0160097"}


id: GO:0018570
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: p-cumate + NADH + H+ + O2 = NAD+ + cis-2,3-dihydroxy-2,3-dihydro-p-cumate.","definition_xrefs":["RHEA:42344"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen","termid":"GO:0016702"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"p-cumate 2,3-dioxygenase activity","secondary_identifiers":["EC:1.14.12.25","MetaCyc:RXN-664","UM-BBD_reactionID:r0395"],"termid":"GO:0018570"}


id: PBO:0063083
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3'-phosphoadenosine 5'-phosphosulfate synthase 2","termid":"PBO:0063083"}


id: FYPO:0008063
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the intracellular calcium ion (Ca2+) concentration briefly increases abnormally, or does not change, immediately following osmotic shock. Normally, the intracellular Ca2+ concentration increases to a peak in a \\\"burst\\\" within one minute, and then decreases to a new steady-state concentration.","definition_xrefs":["PMID:36200871"],"direct_ancestors":[{"relation_name":"is_a","term_name":"altered cellular calcium level","termid":"FYPO:0001462"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"decreased immediate intracellular calcium spike following osmotic shock","termid":"FYPO:0008063"}


id: GO:0007049
data:
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id: FYPO:0005171
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  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of uracil into the cell occurs to a lower extent than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal uracil import","termid":"FYPO:0005170"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0005447","FYPO:0000002","FYPO:0001320","FYPO:0001985"],"is_obsolete":false,"name":"decreased uracil import","synonyms":[{"name":"decreased uracil import across plasma membrane","type":"exact"},{"name":"decreased uracil import during mitotic cell cycle","type":"related"},{"name":"decreased uracil import during vegetative growth","type":"exact"},{"name":"decreased uracil import into cell","type":"exact"},{"name":"decreased uracil uptake","type":"exact"},{"name":"reduced uracil import","type":"exact"}],"termid":"FYPO:0005171"}


id: FYPO:0005186
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of hexavalent chromium ions (Cr6+) than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased resistance to chemical during vegetative growth","termid":"FYPO:0000126"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0002682"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000139","FYPO:0000003","FYPO:0005447","FYPO:0002682"],"is_obsolete":false,"name":"resistance to hexavalent chromium","synonyms":[{"name":"resistance to Cr(VI)","type":"exact"},{"name":"resistance to Cr6+","type":"exact"},{"name":"resistance to chromium(6+)","type":"exact"},{"name":"resistance to chromium(VI) cation","type":"exact"},{"name":"resistance to hexavalent chromium during mitotic cell cycle","type":"related"},{"name":"resistance to hexavalent chromium during vegetative growth","type":"exact"},{"name":"resistance to hexavalent chromium ion","type":"exact"},{"name":"resistance to hexavalent chromium ions","type":"exact"},{"name":"resistant to hexavalent chromium","type":"exact"}],"termid":"FYPO:0005186"}


id: FYPO:0000816
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which the concentration of a substance released into the growth medium by cells is lower than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"altered effect on growth medium","termid":"FYPO:0001155"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001155"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001155","FYPO:0001985"],"is_obsolete":false,"name":"decreased concentration of substance in growth medium","synonyms":[{"name":"decreased accumulation of substance in growth medium","type":"related"},{"name":"decreased level of substance in growth medium","type":"exact"},{"name":"decreased release of substance into growth medium","type":"related"},{"name":"reduced concentration of substance in growth medium","type":"exact"}],"termid":"FYPO:0000816"}


id: PBO:0000848
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitotic cohesin complex subunit Psm3","termid":"PBO:0000848"}


id: PBO:0087650
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of the heterodimeric FACT complex (Spt16p-Pob3p); FACT associates with chromatin via interaction with Nhp6Ap and Nhp6Bp, and reorganizes nucleosomes to facilitate access to DNA by RNA and DNA polymerases; protein abundance increases in response to DNA replication stress","termid":"PBO:0087650"}


id: GO:0051674
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process in which a cell is transported to, and/or maintained in, a specific location.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular process","termid":"GO:0009987"},{"relation_name":"is_a","term_name":"localization","termid":"GO:0051179"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0008150","GO:0051179"],"is_obsolete":false,"name":"localization of cell","synonyms":[{"name":"cell localization","type":"exact"},{"name":"establishment and maintenance of cell localization","type":"exact"},{"name":"establishment and maintenance of localization of cell","type":"exact"},{"name":"localisation of cell","type":"exact"}],"termid":"GO:0051674"}


id: MONDO:0009165
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any Aicardi-Goutieres syndrome in which the cause of the disease is a mutation in the TREX1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Aicardi-Goutieres syndrome","termid":"MONDO:0018866"},{"relation_name":"is_a","term_name":"TREX1-related type 1 interferonopathy","termid":"MONDO:0700256"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0005559","MONDO:0005046"],"is_obsolete":false,"name":"Aicardi-Goutieres syndrome 1","secondary_identifiers":["UMLS:C0796126","OMIM:225750","GARD:15167","MEDGEN:162912","NCIT:C165501"],"synonyms":[{"name":"AGS1","type":"related"},{"name":"Ags","type":"related"},{"name":"Aicardi-Goutieres syndrome 1","type":"exact"},{"name":"Aicardi-Goutieres syndrome 1, autosomal dominant","type":"related"},{"name":"Aicardi-Goutieres syndrome 1, dominant and recessive","type":"exact"},{"name":"Aicardi-Goutieres syndrome caused by mutation in TREX1","type":"exact"},{"name":"Aicardi-Goutieres syndrome type 1","type":"exact"},{"name":"Cree encephalitis","type":"related"},{"name":"Pseudotoxoplasmosis syndrome","type":"related"},{"name":"TREX1 Aicardi-Goutieres syndrome","type":"exact"},{"name":"encephalopathy, familial infantile, with intracranial calcification and chronic cerebrospinal fluid lymphocytosis","type":"related"}],"termid":"MONDO:0009165","xrefs":{"Monarch":{"xref_id":"0009165"}}}


id: PBO:0078431
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Gly (anticodon TCC) 2-1","termid":"PBO:0078431"}


id: MONDO:1010107
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Acute intermittent porphyria that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acute disease, non-human animal","termid":"MONDO:1011300"},{"relation_name":"is_a","term_name":"integumentary system disorder, non-human animal","termid":"MONDO:1011328"},{"relation_name":"is_a","term_name":"porphyria, non-human animal","termid":"MONDO:1011418"},{"relation_name":"is_a","term_name":"liver disorder, non-human animal","termid":"MONDO:1012967"},{"relation_name":"is_a","term_name":"inborn errors of metabolism, non-human animal","termid":"MONDO:1012979"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acute intermittent porphyria, non-human animal","secondary_identifiers":["OMIA:001493"],"termid":"MONDO:1010107","xrefs":{"Monarch":{"xref_id":"1010107"}}}


id: PBO:0034649
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-globally_decreased_mitotic_recombination","termid":"PBO:0034649"}


id: GO:0036099
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process by which an organism or tissue maintains a population of female germ-line stem cells.","definition_xrefs":["GOC:sart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"germ-line stem cell population maintenance","termid":"GO:0030718"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"female germ-line stem cell population maintenance","termid":"GO:0036099"}


id: GO:1903945
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of hepatocyte apoptotic process.","definition_xrefs":["GO_REF:0000058","PMID:8649852","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of hepatocyte apoptotic process","termid":"GO:1903943"},{"relation_name":"is_a","term_name":"positive regulation of epithelial cell apoptotic process","termid":"GO:1904037"},{"relation_name":"positively_regulates","term_name":"hepatocyte apoptotic process","termid":"GO:0097284"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of hepatocyte apoptotic process","synonyms":[{"name":"activation of hepatocyte apoptosis","type":"narrow"},{"name":"activation of hepatocyte apoptotic process","type":"narrow"},{"name":"positive regulation of hepatocyte apoptosis","type":"narrow"},{"name":"up regulation of hepatocyte apoptosis","type":"narrow"},{"name":"up regulation of hepatocyte apoptotic process","type":"exact"},{"name":"up-regulation of hepatocyte apoptosis","type":"narrow"},{"name":"up-regulation of hepatocyte apoptotic process","type":"exact"},{"name":"upregulation of hepatocyte apoptosis","type":"narrow"},{"name":"upregulation of hepatocyte apoptotic process","type":"exact"}],"termid":"GO:1903945"}


id: GO:0071908
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Determination of the asymmetric location of the intestine loops with respect to the left and right halves of the organism.","definition_xrefs":["GOC:cvs"],"direct_ancestors":[{"relation_name":"is_a","term_name":"determination of digestive tract left/right asymmetry","termid":"GO:0071907"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"determination of intestine left/right asymmetry","termid":"GO:0071908"}


id: FYPO:0006772
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype in which actin cortical patches are localized throughout the cell cortex during mating. Normally, actin cortical patches concentrate in the mating projection tip and conjugation bridge during cell fusion, and then disperse after karyogamy.","definition_xrefs":["PMID:20123972","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mislocalized actin cortical patches","termid":"FYPO:0006771"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002"],"is_obsolete":false,"name":"dispersed actin cortical patch localization during mating","synonyms":[{"name":"delocalised actin cortical patches during mating","type":"exact"},{"name":"delocalized actin cortical patches during mating","type":"exact"},{"name":"depolarized actin cortical patch localization during mating","type":"exact"},{"name":"dispersed F-actin patch localization during mating","type":"exact"},{"name":"dispersed actin cortical patch localisation during mating","type":"exact"},{"name":"dispersed actin cortical patch localization during conjugation with cellular fusion","type":"exact"},{"name":"dispersed actin cortical patch location during mating","type":"related"},{"name":"dispersed actin patch localization during mating","type":"exact"}],"termid":"FYPO:0006772"}


id: GO:1990639
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: D-myo-inositol 3,4,5-trisphosphate + H2O = myo-inositol 3,4-bisphosphate + phosphate.","definition_xrefs":["PMID:11348594"],"gene_count":0,"genotype_count":0,"name":"obsolete inositol-3,4,5-trisphosphate 5-phosphatase activity (obsolete GO:1990639)","synonyms":[{"name":"inositol-3,4,5-trisphosphate 5-phosphatase activity","type":"exact"}],"termid":"GO:1990639"}


id: PR:O13718
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- vtc2 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O13718"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vacuolar transporter chaperone 2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC14C4.11","synonyms":[{"name":"Spom972h-vtc2","type":"exact"}],"termid":"PR:O13718"}


id: PATO:0001698
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A photosensitivity which is relatively high.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"increased_in_magnitude_relative_to","term_name":"normal","termid":"PATO:0000461"},{"relation_name":"is_a","term_name":"photosensitive","termid":"PATO:0000547"},{"relation_name":"is_a","term_name":"increased object quality","termid":"PATO:0002305"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"increased photosensitivity","synonyms":[{"name":"high photosensitivity","type":"exact"}],"termid":"PATO:0001698"}


id: GO:0070653
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a high-density lipoprotein receptor.","definition_xrefs":["GOC:mah","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lipoprotein particle receptor binding","termid":"GO:0070325"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005515"}],"interesting_parent_ids":["GO:0003674","GO:0005515","GO:0005488"],"is_obsolete":false,"name":"high-density lipoprotein particle receptor binding","synonyms":[{"name":"HDL receptor binding","type":"exact"},{"name":"high-density lipoprotein receptor binding","type":"exact"}],"termid":"GO:0070653"}


id: PBO:0061495
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nurim","termid":"PBO:0061495"}


id: PBO:0060861
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NIMA-related kinase 4 pseudogene 3","termid":"PBO:0060861"}


id: PBO:0028711
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_regional_homologous_chromosome_pairing","termid":"PBO:0028711"}


id: GO:0010127
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions using mycothiol to convert an alkylating agent to an S-conjugate of mycothiol. The latter is cleaved to release mercapturic acid which is excreted from the cell.","definition_xrefs":["GOC:pz"],"direct_ancestors":[{"relation_name":"is_a","term_name":"detoxification","termid":"GO:0098754"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0098754"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0098754"],"is_obsolete":false,"name":"mycothiol-dependent detoxification","synonyms":[{"name":"mycothiol-dependent detoxification of alkylating agent","type":"narrow"}],"termid":"GO:0010127"}


id: PBO:0089162
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kinesin-14 family minus-end directed microtubule motor Klp2","termid":"PBO:0089162"}


id: PBO:0045512
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DSTN pseudogene 4","termid":"PBO:0045512"}


id: PBO:0063068
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pannexin 1","termid":"PBO:0063068"}


id: PBO:0045993
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"EP300 interacting inhibitor of differentiation 1","termid":"PBO:0045993"}


id: MONDO:0015589
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare disorder characterized by degenerative changes in the limbic area of the brain. Causes include infections and autoimmune conditions; it may also manifest as a paraneoplastic syndrome, most often caused by small cell lung carcinoma. Signs and symptoms include behavioral changes, hallucinations and dementia.","definition_xrefs":["NCIT:C4350"],"direct_ancestors":[{"relation_name":"is_a","term_name":"limbic encephalitis","termid":"MONDO:0015588"},{"relation_name":"is_a","term_name":"paraneoplastic neurologic syndrome","termid":"MONDO:0018215"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"paraneoplastic limbic encephalitis","secondary_identifiers":["Orphanet:163895","icd11.foundation:1147819644","ICD9:323.81","SCTID:445014002"],"synonyms":[{"name":"limbic encephalitis","type":"broad"}],"termid":"MONDO:0015589","xrefs":{"Monarch":{"xref_id":"0015589"}}}


id: PBO:0059865
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myotubularin related protein 2","termid":"PBO:0059865"}


id: MONDO:0008345
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete idiopathic pulmonary fibrosis (obsolete MONDO:0008345)","secondary_identifiers":["NANDO:1200417"],"termid":"MONDO:0008345","xrefs":{"Monarch":{"xref_id":"0008345"}}}


id: PBO:0047675
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FOXP3 regulating long intergenic non-coding RNA","termid":"PBO:0047675"}


id: PBO:0073676
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"signal regulatory protein gamma","termid":"PBO:0073676"}


id: GO:0098627
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: phospho-L-arginyl-[protein] +H2O = L-arginyl-[protein] + phosphate.","definition_xrefs":["RHEA:43380","PMID:23770242"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphoprotein phosphatase activity","termid":"GO:0004721"},{"relation_name":"is_a","term_name":"hydrolase activity, acting on acid phosphorus-nitrogen bonds","termid":"GO:0016825"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0004721"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0140096","GO:0004721","GO:0016787","GO:0003824","GO:0003674","GO:0016788"],"is_obsolete":false,"name":"protein arginine phosphatase activity","secondary_identifiers":["EC:3.9.1.2"],"termid":"GO:0098627"}


id: MONDO:0100319
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A inflammatory syndrome in adults infected by the SARS-CoV-2 with severe illness requiring hospitalization in a person aged ≥21 years; a positive test result for current or previous SARS-CoV-2 infection (nucleic acid, antigen, or antibody) during admission or in the previous 12 weeks; severe dysfunction of one or more extrapulmonary organ systems (e.g., hypotension or shock, cardiac dysfunction, arterial or venous thrombosis or thromboembolism, or acute liver injury); laboratory evidence of severe inflammation (e.g., elevated CRP, ferritin, D-dimer, or interleukin-6); and absence of severe respiratory illness (to exclude patients in which inflammation and organ dysfunction might be attributable simply to tissue hypoxia).","definition_xrefs":["PMID:33031361"],"direct_ancestors":[{"relation_name":"is_a","term_name":"multisystem inflammatory syndrome in children and adults","termid":"MONDO:0035375"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"COVID-19–associated multisystem inflammatory syndrome in adults","synonyms":[{"name":"MIS-A","type":"exact"}],"termid":"MONDO:0100319","xrefs":{"Monarch":{"xref_id":"0100319"}}}


id: GO:0090414
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of molybdate ions out of the vacuole.","definition_xrefs":["GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"molybdate ion transport","termid":"GO:0015689"},{"relation_name":"is_a","term_name":"vacuolar transmembrane transport","termid":"GO:0034486"},{"relation_name":"is_a","term_name":"inorganic anion transmembrane transport","termid":"GO:0098661"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0051179","GO:0055085","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"molybdate ion export from vacuole","termid":"GO:0090414"}


id: PBO:0053141
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lactate dehydrogenase A like 6C, pseudogene","termid":"PBO:0053141"}


id: PBO:0054055
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1397","termid":"PBO:0054055"}


id: GO:2001139
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid transport.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of lipid transport","termid":"GO:0032369"},{"relation_name":"is_a","term_name":"regulation of phospholipid transport","termid":"GO:2001138"},{"relation_name":"negatively_regulates","term_name":"phospholipid transport","termid":"GO:0015914"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"negatively_regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0008150"],"is_obsolete":false,"name":"negative regulation of phospholipid transport","termid":"GO:2001139"}


id: GO:0140759
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 56) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 56). This reaction is the addition of a methyl group to the lysine residue at position 56 of the histone H3 protein.","definition_xrefs":["PMID:28743002","PMID:23451023"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-lysine N-methyltransferase activity","termid":"GO:0016279"},{"relation_name":"is_a","term_name":"histone H3 methyltransferase activity","termid":"GO:0140938"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008276"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0008276","GO:0016741","GO:0016740","GO:0003824","GO:0140096","GO:0003674"],"is_obsolete":false,"name":"histone H3K56 methyltransferase activity","synonyms":[{"name":"histone H3K56 methylase activity","type":"exact"},{"name":"histone lysine N-methyltransferase activity (H3-K56 specific)","type":"exact"},{"name":"histone methyltransferase activity (H3-K56 specific)","type":"exact"},{"name":"histone-H3K56 methyltransferase activity","type":"exact"}],"termid":"GO:0140759"}


id: GO:0019079
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process involved directly in viral genome replication, including viral nucleotide metabolism.","definition_xrefs":["ISBN:0781702534"],"direct_ancestors":[{"relation_name":"is_a","term_name":"viral process","termid":"GO:0016032"},{"relation_name":"part_of","term_name":"viral life cycle","termid":"GO:0019058"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"viral genome replication","synonyms":[{"name":"sigma virus replication","type":"narrow"},{"name":"viral replication","type":"broad"}],"termid":"GO:0019079"}


id: PR:Q9Y7L0
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A vesicle-trafficking protein SEC22b that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["UniProtKB:Q9Y7L0","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein transport protein sec22 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC2A9.08c","synonyms":[{"name":"Spom972h-SEC22B","type":"exact"}],"termid":"PR:Q9Y7L0"}


id: PBO:0042809
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"competing endogenous lncRNA 3 for miR-645","termid":"PBO:0042809"}


id: MONDO:0007290
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any cataract (disease) in which the cause of the disease is a mutation in the HSF4 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"early-onset non-syndromic cataract","termid":"MONDO:0011060"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"cataract 5 multiple types","secondary_identifiers":["UMLS:C0266537","MEDGEN:78608","OMIM:116800","MESH:C535342","DOID:0110255"],"synonyms":[{"name":"CTRCT5","type":"exact"},{"name":"HSF4 cataract (disease)","type":"exact"},{"name":"cataract (disease) caused by mutation in HSF4","type":"exact"},{"name":"cataract 5, multiple types","type":"related"},{"name":"cataract, Marner type","type":"related"},{"name":"cataract, lamellar","type":"related"}],"termid":"MONDO:0007290","xrefs":{"Monarch":{"xref_id":"0007290"}}}


id: GO:1990442
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to nitrosative stress; a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.","definition_xrefs":["GOC:bf","PMID:23985028","GOC:PARL"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to nitrosative stress","termid":"GO:0071500"},{"relation_name":"is_a","term_name":"intrinsic apoptotic signaling pathway","termid":"GO:0097193"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"intrinsic apoptotic signaling pathway in response to nitrosative stress","synonyms":[{"name":"nitrosative stress-induced apoptosis","type":"related"},{"name":"nitrosative stress-induced intrinsic apoptotic signaling pathway","type":"exact"}],"termid":"GO:1990442"}


id: GO:0060679
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a ureteric bud splits into three units at its end.","definition_xrefs":["PMID:16916378","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"morphogenesis of an epithelium","termid":"GO:0002009"},{"relation_name":"part_of","term_name":"branching involved in ureteric bud morphogenesis","termid":"GO:0001658"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"trifid subdivision of terminal units involved in ureteric bud branching","termid":"GO:0060679"}


id: PBO:0043721
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome c oxidase subunit 6C","termid":"PBO:0043721"}


id: PBO:0034169
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-existence_ends_during","termid":"PBO:0034169"}


id: PBO:0068160
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 467","termid":"PBO:0068160"}


id: MONDO:0002609
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete gangliosidosis GM1 (obsolete MONDO:0002609)","termid":"MONDO:0002609","xrefs":{"Monarch":{"xref_id":"0002609"}}}


id: GO:0051877
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of dispersed pigment granules towards the center of the cell.","definition_xrefs":["GOC:mh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"establishment of pigment granule localization","termid":"GO:0051905"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0051179","GO:0008150"],"is_obsolete":false,"name":"pigment granule aggregation in cell center","termid":"GO:0051877"}


id: PBO:0090316
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA-binding transcription factor Esc1","termid":"PBO:0090316"}


id: PBO:0084665
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial acetyl-coenzyme A carboxylase; catalyzes production of malonyl-CoA in mitochondrial fatty acid biosynthesis; relocalizes from mitochondrion to cytoplasm upon DNA replication stress; genetic and comparative analysis suggests that translation begins at a non-canonical (Ile) start codon at -372 relative to the annotated start codon","termid":"PBO:0084665"}


id: PBO:0058368
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4740","termid":"PBO:0058368"}


id: PBO:0045555
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dual specificity phosphatase 7","termid":"PBO:0045555"}


id: MONDO:0018253
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"intellectual disability-facial dysmorphism-hand anomalies syndrome","secondary_identifiers":["Orphanet:370010","GARD:21585","MEDGEN:1655582","UMLS:C4750848"],"termid":"MONDO:0018253","xrefs":{"Monarch":{"xref_id":"0018253"}}}


id: MONDO:0044033
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An acute or subacute reversible condition characterized by headaches, mental status changes, visual disturbances, and seizures associated with imaging findings of posterior leukoencephalopathy. It has been observed in association with hypertensive encephalopathy, eclampsia, and immunosuppressive and cytotoxic drug treatment.","definition_xrefs":["NCIT:C78598"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"hypertensive encephalopathy","termid":"MONDO:0006796"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"posterior leukoencephalopathy syndrome","secondary_identifiers":["MEDGEN:163898","MESH:D054038","SCTID:450886002","UMLS:C0878576"],"synonyms":[{"name":"PRES","type":"exact"},{"name":"Posterior reversible encephalopathy syndrome","type":"exact"},{"name":"RPLE","type":"exact"},{"name":"leukoencephalopathy syndrome, Posterior","type":"related"},{"name":"leukoencephalopathy syndromes, Posterior","type":"related"},{"name":"posterior reversible encephalopathy syndrome","type":"exact"},{"name":"reversible Posterior cerebral edema syndrome","type":"exact"},{"name":"reversible Posterior cerebral oedema syndrome","type":"exact"},{"name":"reversible Posterior leukoencephalopathy syndrome","type":"exact"},{"name":"reversible occipital parietal encephalopathy","type":"exact"},{"name":"reversible posterior leukoencephalopathy syndrome","type":"exact"},{"name":"syndrome, Posterior leukoencephalopathy","type":"related"},{"name":"syndromes, Posterior leukoencephalopathy","type":"related"}],"termid":"MONDO:0044033","xrefs":{"Monarch":{"xref_id":"0044033"}}}


id: MONDO:0035407
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"furuncular myiasis","termid":"MONDO:0018941"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"furuncular myiasis due to Cordylobia anthropophaga","secondary_identifiers":["UMLS:C4511624","ICD10CM:B87.0","MEDGEN:1386398","GARD:22260","Orphanet:563687"],"synonyms":[{"name":"furunculoid myiasis due to Cordylobia anthropophaga","type":"exact"},{"name":"furunculous myiasis due to Cordylobia anthropophaga","type":"exact"}],"termid":"MONDO:0035407","xrefs":{"Monarch":{"xref_id":"0035407"}}}


id: PBO:0082788
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of the TOM (Translocase of Outer Membrane) complex; responsible for initial import of mitochondrially directed proteins; mediates interaction between TOM and TIM complexes and acts as receptor for precursor proteins; implicated in mitochondrial accumulation of amyloid β (Aβ) peptides via direct interaction with Aβ peptide residues 25-42 followed by transfer to Tom40p and transport through the TOM channel","termid":"PBO:0082788"}


id: PBO:0060295
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MYL6 pseudogene 3","termid":"PBO:0060295"}


id: MONDO:0003998
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. An adenoma that arises from the vagina and is characterized by a tubular architectural pattern.","definition_xrefs":["NCIT:C40257"],"gene_count":0,"genotype_count":0,"name":"obsolete vaginal tubular adenoma (obsolete MONDO:0003998)","secondary_identifiers":["DOID:6809"],"synonyms":[{"name":"vaginal tubular adenoma","type":"exact"}],"termid":"MONDO:0003998","xrefs":{"Monarch":{"xref_id":"0003998"}}}


id: MONDO:0013047
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A condition that affects how the body breaks down sugar to use as energy in muscle cells. People withthis conditionexperience fatigue, muscle pain, and cramps during exercise (exercise intolerance). In some people,high-intensity exercise or other strenuous activity leads to the breakdown of muscle tissue (rhabdomyolysis), which can lead to myoglobinuria (rust-colored urine indicating breakdown of muscle tissue) and kidney damage. A skin rash may also develop. The severity of the signs and symptoms varies greatly among affected individuals. Lactate dehydrogenase A deficiency is caused by mutations in the LDHA gene. This condition is inherited in an autosomal recessive pattern.","definition_xrefs":["GARD:0003160"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete muscular glycogenosis (obsolete MONDO:0016118)","termid":"MONDO:0016118"},{"relation_name":"excluded_subClassOf","term_name":"glycogen storage disease due to lactate dehydrogenase deficiency","termid":"MONDO:0016527"},{"relation_name":"is_a","term_name":"disorder of glycogen metabolism","termid":"MONDO:0002412"},{"relation_name":"is_a","term_name":"disorder of glycolysis","termid":"MONDO:0017688"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0037792"},{"rel_name":"is_a","termid":"MONDO:0019254"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0037792","MONDO:0019254","MONDO:0005066"],"is_obsolete":false,"name":"glycogen storage disease due to lactate dehydrogenase M-subunit deficiency","secondary_identifiers":["NANDO:1200833","UMLS:C2931743","MEDGEN:419152","OMIM:612933","Orphanet:284426","HGNC:6535","GARD:3160","ICD9:271.8","MESH:C538133","SCTID:237982007"],"synonyms":[{"name":"GSD 11","type":"related"},{"name":"GSD XI","type":"related"},{"name":"GSD due to lactate dehydrogenase M-subunit deficiency","type":"exact"},{"name":"GSD type 11","type":"related"},{"name":"GSD11","type":"related"},{"name":"LDH-M subunit deficiency","type":"exact"},{"name":"LDHA glycogen storage disease","type":"exact"},{"name":"glycogen storage disease XI","type":"related"},{"name":"glycogen storage disease caused by mutation in LDHA","type":"exact"},{"name":"glycogen storage disease type 11","type":"related"},{"name":"glycogenosis due to lactate dehydrogenase M-subunit deficiency","type":"exact"},{"name":"glycogenosis type 11","type":"related"},{"name":"lactate dehydrogenase A deficiency","type":"exact"},{"name":"lactate dehydrogenase deficiency type A","type":"related"}],"termid":"MONDO:0013047","xrefs":{"Monarch":{"xref_id":"0013047"}}}


id: PBO:0076011
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"stress induced phosphoprotein 1 pseudogene 2","termid":"PBO:0076011"}


id: PBO:0042002
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CCDC54 antisense RNA 1","termid":"PBO:0042002"}


id: GO:0030052
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. A peptidyl-prolyl isomerase isolated from Escherichia coli. It does not have any function as an immunophilin.","definition_xrefs":["ISBN:0198506732"],"gene_count":0,"genotype_count":0,"name":"obsolete parvulin (obsolete GO:0030052)","synonyms":[{"name":"parvulin","type":"exact"}],"termid":"GO:0030052"}


id: PBO:0043555
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"collagen type IV alpha 4 chain","termid":"PBO:0043555"}


id: MONDO:0012679
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any autosomal recessive malignant osteopetrosis in which the cause of the disease is a mutation in the PLEKHM1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive osteopetrosis","termid":"MONDO:0019026"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328","MONDO:0006025"],"is_obsolete":false,"name":"autosomal recessive osteopetrosis 6","secondary_identifiers":["MESH:C566931","Orphanet:210110","OMIM:611497","UMLS:C1969093","DOID:0110945","GARD:4156","MEDGEN:409754"],"synonyms":[{"name":"OPTB6","type":"exact"},{"name":"PLEKHM1 osteopetrosis (disease)","type":"exact"},{"name":"autosomal recessive intermediate osteopetrosis","type":"exact"},{"name":"autosomal recessive osteopetrosis intermediate form","type":"exact"},{"name":"autosomal recessive osteopetrosis type 6","type":"exact"},{"name":"intermediate osteopetrosis","type":"related"},{"name":"osteopetrosis (disease) caused by mutation in PLEKHM1","type":"exact"},{"name":"osteopetrosis autosomal recessive 6","type":"related"},{"name":"osteopetrosis autosomal recessive intermediate form","type":"related"},{"name":"osteopetrosis, autosomal recessive 6","type":"related"},{"name":"osteopetrosis, autosomal recessive type 6","type":"exact"},{"name":"osteopetrosis, autosomal recessive, Intermediate form","type":"related"}],"termid":"MONDO:0012679","xrefs":{"Monarch":{"xref_id":"0012679"}}}


id: GO:0009274
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protective structure outside the cytoplasmic membrane composed of peptidoglycan (also known as murein), a molecule made up of a glycan (sugar) backbone of repetitively alternating N-acetylglucosamine and N-acetylmuramic acid with short, attached, cross-linked peptide chains containing unusual amino acids. An example of this component is found in Escherichia coli.","definition_xrefs":["ISBN:0815108893","GOC:mlg"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell wall","termid":"GO:0005618"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005618"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0005618"],"is_obsolete":false,"name":"peptidoglycan-based cell wall","synonyms":[{"name":"envelope","type":"broad"},{"name":"murein sacculus","type":"related"},{"name":"peptidoglycan","type":"narrow"}],"termid":"GO:0009274"}


id: PBO:0027284
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_protein_localization_to_nucleus_during_cellular_response_to_salt_stress","termid":"PBO:0027284"}


id: MONDO:0005223
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An acute myeloid leukemia (AML) in which the blasts do not show evidence of myeloid differentiation by morphology and conventional cytochemistry. (WHO, 2001)","definition_xrefs":["NCIT:C8460"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"bilineal acute myeloid leukemia","termid":"MONDO:0011118"},{"relation_name":"is_a","term_name":"acute myeloid leukemia by FAB classification","termid":"MONDO:0015667"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0005046","MONDO:0004992"],"is_obsolete":false,"name":"acute myeloid leukemia with minimal differentiation","secondary_identifiers":["ONCOTREE:AMLMD","EFO:0003026","DOID:0081085","GARD:19588","MEDGEN:101100","Orphanet:98832","NANDO:2200004","UMLS:C0522631","icd11.foundation:1468530237","MONDO:0020318","ICDO:9872/3"],"synonyms":[{"name":"AML M0","type":"exact"},{"name":"AML with minimal differentiation","type":"exact"},{"name":"AMLMD","type":"related"},{"name":"M0 acute granulocytic leukaemia","type":"exact"},{"name":"M0 acute granulocytic leukaemia with minimal differentiation","type":"exact"},{"name":"M0 acute granulocytic leukemia","type":"exact"},{"name":"M0 acute granulocytic leukemia with minimal differentiation","type":"exact"},{"name":"M0 acute myeloblastic leukaemia","type":"exact"},{"name":"M0 acute myeloblastic leukemia","type":"exact"},{"name":"M0 acute myelocytic leukaemia","type":"exact"},{"name":"M0 acute myelocytic leukemia","type":"exact"},{"name":"M0 acute myelogenous leukaemia","type":"exact"},{"name":"M0 acute myelogenous leukaemia with minimal differentiation","type":"exact"},{"name":"M0 acute myelogenous leukemia","type":"exact"},{"name":"M0 acute myelogenous leukemia with minimal differentiation","type":"exact"},{"name":"M0 myeloid leukaemia","type":"exact"},{"name":"M0 myeloid leukaemia with minimal differentiation","type":"exact"},{"name":"M0 myeloid leukemia","type":"exact"},{"name":"M0 myeloid leukemia with minimal differentiation","type":"exact"},{"name":"acute myeloblastic leukaemia with minimal differentiation","type":"exact"},{"name":"acute myeloblastic leukemia with minimal differentiation","type":"exact"},{"name":"acute myeloblastic leukemia, minimally differentiated","type":"exact"},{"name":"acute myelocytic leukaemia with minimal differentiation","type":"exact"},{"name":"acute myelocytic leukemia with minimal differentiation","type":"exact"},{"name":"acute myelogenous leukaemia with minimal differentiation","type":"exact"},{"name":"acute myelogenous leukemia with minimal differentiation","type":"exact"},{"name":"acute myeloid leukaemia with minimal differentiation (MO)","type":"exact"},{"name":"acute myeloid leukemia with minimal differentiation","type":"exact"},{"name":"acute myeloid leukemia with minimal differentiation (MO)","type":"exact"},{"name":"acute myeloid leukemia, minimally differentiated","type":"exact"},{"name":"minimally differentiated acute myeloblastic leukaemia","type":"exact"},{"name":"minimally differentiated acute myeloblastic leukemia","type":"exact"}],"termid":"MONDO:0005223","xrefs":{"Monarch":{"xref_id":"0005223"}}}


id: PBO:0036052
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_histone_H3-K9_dimethylation_at_centromere_outer_repeat_during_vegetative_growth","termid":"PBO:0036052"}


id: PBO:0031660
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-pseudohyphal_growth_abolished","termid":"PBO:0031660"}


id: MOD:00694
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively substitutes a halogen atom for a hydrogen atom.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein modification categorized by chemical process","termid":"MOD:01156"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"halogen containing residue","synonyms":[{"name":"HalRes","type":"exact"},{"name":"halogenated residue","type":"exact"}],"termid":"MOD:00694"}


id: PBO:0064232
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PLCH1 antisense RNA 2","termid":"PBO:0064232"}


id: PBO:0082599
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Clathrin coat accessory factor; involved in clathrin-mediated vesicle trafficking; may function to link the AP-1 clathrin adaptor complex with the Rab GTPase Ypt31p; has structural similarity to G-proteins; mouse homolog Aagab (p34) functionally complements irc6 null mutation; null mutant displays increased levels of spontaneous Rad52p foci","termid":"PBO:0082599"}


id: MONDO:1011982
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"vision disorder, non-human animal","termid":"MONDO:1011367"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"rod-cone dysplasia, non-human animal","secondary_identifiers":["OMIA:000881"],"termid":"MONDO:1011982","xrefs":{"Monarch":{"xref_id":"1011982"}}}


id: GO:1901278
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving D-ribose 5-phosphate.","definition_xrefs":["GOC:TermGenie","GOC:yaf","UniPathway:UPA00293"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ribose phosphate metabolic process","termid":"GO:0019693"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"D-ribose 5-phosphate metabolic process","synonyms":[{"name":"D-ribose 5-phosphate metabolism","type":"exact"}],"termid":"GO:1901278"}


id: MONDO:0008056
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Steinert disease, also known as myotonic dystrophy type 1, is a muscle disease characterized by myotonia and by multiorgan damage that combines various degrees of muscle weakness, arrhythmia and/or cardiac conduction disorders, cataract, endocrine damage, sleep disorders and baldness.","definition_xrefs":["Orphanet:273"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete neuro-ophthalmological disease (obsolete MONDO:0015368)","termid":"MONDO:0015368"},{"relation_name":"is_a","term_name":"myotonic dystrophy","termid":"MONDO:0016107"},{"relation_name":"is_a","term_name":"familial hypertrophic cardiomyopathy","termid":"MONDO:0024573"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"},{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267","MONDO:0005336"],"is_obsolete":false,"name":"myotonic dystrophy type 1","secondary_identifiers":["DOID:11722","NCIT:C84679","ICD9:359.21","OMIM:160900","NORD:1075","MEDGEN:886881","UMLS:C3250443","icd11.foundation:557405480","GARD:8310"],"synonyms":[{"name":"DM1","type":"exact"},{"name":"DMPK myotonic dystrophy","type":"exact"},{"name":"MD1","type":"exact"},{"name":"Myotonic Dystrophy","type":"exact"},{"name":"Steinert disease","type":"exact"},{"name":"Steinert myotonic dystrophy","type":"related"},{"name":"Steinert myotonic dystrophy syndrome","type":"exact"},{"name":"Steinert syndrome","type":"exact"},{"name":"Steinert's disease","type":"related"},{"name":"dystrophia myotonica","type":"exact"},{"name":"dystrophia myotonica 1","type":"related"},{"name":"dystrophia myotonica type 1","type":"related"},{"name":"myotonic dystrophy 1","type":"related"},{"name":"myotonic dystrophy caused by mutation in DMPK","type":"exact"},{"name":"myotonic dystrophy of Steinert","type":"exact"},{"name":"myotonic dystrophy type 1","type":"exact"}],"termid":"MONDO:0008056","xrefs":{"Monarch":{"xref_id":"0008056"}}}


id: MONDO:0008269
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Polydactyly of a biphalangeal thumb or PPD1 is the most common form of preaxial polydactyly of fingers, a limb malformation syndrome, that is characterized by the duplication of one or more skeletal components of a biphalangeal thumb. Hands are preferentially affected (in bilateral), and the right hand is more commonly involved than the left.","definition_xrefs":["Orphanet:93339"],"direct_ancestors":[{"relation_name":"is_a","term_name":"preaxial polydactyly of fingers","termid":"MONDO:0017425"},{"relation_name":"is_a","term_name":"polydactyly-syndactyly-triphalangism","termid":"MONDO:0800066"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"polydactyly of a biphalangeal thumb","secondary_identifiers":["MEDGEN:237235","OMIM:174400","MESH:C536332","GARD:4417","SCTID:445216006","UMLS:C1395852"],"synonyms":[{"name":"Fromont anomaly","type":"related"},{"name":"PPD1","type":"exact"},{"name":"polydactyly preaxial 1","type":"related"},{"name":"polydactyly, preaxial 1","type":"related"},{"name":"polydactyly, preaxial I","type":"related"},{"name":"polydactyly, preaxial type 1","type":"exact"},{"name":"preaxial polydactyly 1","type":"related"},{"name":"preaxial polydactyly type 1","type":"exact"},{"name":"thenar hypoplasia","type":"related"},{"name":"thumb polydactyly","type":"related"}],"termid":"MONDO:0008269","xrefs":{"Monarch":{"xref_id":"0008269"}}}


id: PBO:0027935
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_viability_in_stationary_phase_during_glucose_starvation","termid":"PBO:0027935"}


id: PR:O13988
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protection of telomeres protein 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","PANTHER:PTHR14513:SF0"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protection of telomeres protein 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC26H5.06","secondary_identifiers":["UniProtKB:O13988"],"synonyms":[{"name":"SPAC26H5.06","type":"related"},{"name":"Spom972h-POT1","type":"exact"}],"termid":"PR:O13988"}


id: MONDO:0019416
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"X-linked intellectual disability-hypogammaglobulinemia-progressive neurological deterioration syndrome is characterized by moderate intellectual deficit, bilateral single palmar creases, seizures, variable hypogammaglobulinemia and characteristic features (synophrys, prognathism, and hirsutism). It has been reported in three males from two generations of one family. All underwent progressive neurological deterioration. This syndrome is transmitted as an X-linked trait, and the causative gene is located between Xq21.33 and Xq23.","definition_xrefs":["Orphanet:85317"],"direct_ancestors":[{"relation_name":"is_a","term_name":"congenital nervous system disorder","termid":"MONDO:0002320"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"},{"relation_name":"is_a","term_name":"X-linked syndromic intellectual disability","termid":"MONDO:0020119"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320"],"is_obsolete":false,"name":"X-linked intellectual disability-hypogammaglobulinemia-progressive neurological deterioration syndrome","secondary_identifiers":["UMLS:C4304919","MEDGEN:930588","GARD:19053"],"termid":"MONDO:0019416","xrefs":{"Monarch":{"xref_id":"0019416"}}}


id: MONDO:0029147
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"spermatogenic failure","termid":"MONDO:0004983"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005047"}],"interesting_parent_ids":["MONDO:0005047"],"is_obsolete":false,"name":"spermatogenic failure 33","secondary_identifiers":["DOID:0111915","MEDGEN:1648473","OMIM:618152","UMLS:C4748395","GARD:18406"],"synonyms":[{"name":"SPERMATOGENIC FAILURE 33","type":"related"},{"name":"SPGF33","type":"related"}],"termid":"MONDO:0029147","xrefs":{"Monarch":{"xref_id":"0029147"}}}


id: MONDO:0001591
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"entropion","termid":"MONDO:0001519"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"senile entropion","secondary_identifiers":["DOID:12836","MEDGEN:509837","ICD9:374.01","SCTID:55408009","UMLS:C0155188"],"synonyms":[{"name":"involutional entropion","type":"exact"}],"termid":"MONDO:0001591","xrefs":{"Monarch":{"xref_id":"0001591"}}}


id: MONDO:0021159
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An salpingitis caused by infection with Neisseria gonorrhoeae.","definition_xrefs":["MONDO:patterns/specific_infectious_disease_by_agent"],"direct_ancestors":[{"relation_name":"is_a","term_name":"salpingitis","termid":"MONDO:0003619"},{"relation_name":"is_a","term_name":"gonorrhea","termid":"MONDO:0004277"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"gonococcal salpingitis","secondary_identifiers":["MEDGEN:574651","SCTID:237038001","UMLS:C0341811"],"synonyms":[{"name":"Neisseria gonorrhoeae caused salpingitis","type":"exact"},{"name":"Neisseria gonorrhoeae salpingitis","type":"exact"}],"termid":"MONDO:0021159","xrefs":{"Monarch":{"xref_id":"0021159"}}}


id: PBO:0030948
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_mitochondrial_fission","termid":"PBO:0030948"}


id: PBO:0081138
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ZFP36 ring finger protein like 1","termid":"PBO:0081138"}


id: PBO:0055661
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lincRNA adipogenesis and lipogenesis associated","termid":"PBO:0055661"}


id: PBO:0051976
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"IZUMO family member 3","termid":"PBO:0051976"}


id: FYPO:0004490
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more transport RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Transport RNAs are transcribed from genes whose products are involved in one or more transport processes.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased RNA level during vegetative growth","termid":"FYPO:0000825"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0006551","FYPO:0001320","FYPO:0000002","FYPO:0005447"],"is_obsolete":false,"name":"increased level of transport gene mRNA during vegetative growth","synonyms":[{"name":"increased level of transport gene RNA during vegetative growth","type":"exact"},{"name":"increased level of transport gene mRNA during mitotic cell cycle","type":"related"},{"name":"increased level of transport gene transcripts during vegetative growth","type":"exact"},{"name":"increased transport gene mRNA accumulation during vegetative growth","type":"related"}],"termid":"FYPO:0004490"}


id: PBO:0070213
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U7 small nuclear 143 pseudogene","termid":"PBO:0070213"}


id: GO:0047106
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (4-hydroxyphenyl)acetaldehyde + H2O + NAD+ = 4-hydroxyphenylacetate + 2 H+ + NADH.","definition_xrefs":["RHEA:17273"],"direct_ancestors":[{"relation_name":"is_a","term_name":"aldehyde dehydrogenase (NAD+) activity","termid":"GO:0004029"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"4-hydroxyphenylacetaldehyde dehydrogenase (NAD+) activity","secondary_identifiers":["MetaCyc:1.2.1.53-RXN","EC:1.2.1.53"],"synonyms":[{"name":"4-HPAL dehydrogenase activity","type":"related"},{"name":"4-hydroxyphenylacetaldehyde:NAD+ oxidoreductase activity","type":"related"}],"termid":"GO:0047106"}


id: FYPO:0006779
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of spermidine than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased resistance to chemical during vegetative growth","termid":"FYPO:0000126"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002682"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0002682","FYPO:0000003","FYPO:0005447","FYPO:0000139"],"is_obsolete":false,"name":"resistance to spermidine","synonyms":[{"name":"resistance to spermidine during mitotic cell cycle","type":"related"},{"name":"resistance to spermidine during vegetative growth","type":"exact"},{"name":"resistant to spermidine","type":"exact"}],"termid":"FYPO:0006779"}


id: PBO:0065373
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pregnancy specific beta-1-glycoprotein 1","termid":"PBO:0065373"}


id: SO:0001551
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A sequence variant that increases the rate of transcription with respect to a reference sequence.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"rate_of_transcription_variant","termid":"SO:0001550"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"increased_transcription_rate_variant","synonyms":[{"name":"increased transcription rate variant","type":"exact"}],"termid":"SO:0001551"}


id: MONDO:1012101
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hemolytic uremic syndrome, non-human animal","termid":"MONDO:1011906"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hemolytic uremic syndrome, cattle","secondary_identifiers":["OMIA:000435-9913"],"termid":"MONDO:1012101","xrefs":{"Monarch":{"xref_id":"1012101"}}}


id: PBO:0063627
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"profilin 1 pseudogene 3","termid":"PBO:0063627"}


id: PBO:0073258
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"septin 7 pseudogene 2","termid":"PBO:0073258"}


id: PBO:0055627
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 3066","termid":"PBO:0055627"}


id: PBO:0076189
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SUMO1 pseudogene 4","termid":"PBO:0076189"}


id: PBO:0053088
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"late cornified envelope 1F","termid":"PBO:0053088"}


id: PBO:0033753
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_proteolysis","termid":"PBO:0033753"}


id: MONDO:0000223
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete chikungunya (obsolete MONDO:0000223)","termid":"MONDO:0000223","xrefs":{"Monarch":{"xref_id":"0000223"}}}


id: PR:O14130
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC3C7.04 gene.","definition_xrefs":["UniProtKB:O14130","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized transcriptional regulatory protein C3C7.04 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC3C7.04","synonyms":[{"name":"Spom972h-SPAC3C7.04","type":"exact"}],"termid":"PR:O14130"}


id: PBO:0032712
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_error-free_translesion_synthesis_of_cyclobutane_pyrimidine_dimers","termid":"PBO:0032712"}


id: GO:0048153
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways resulting in the formation of S100 alpha protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer's disease, Down Syndrome and ALS.","definition_xrefs":["GOC:jid"],"gene_count":0,"genotype_count":0,"name":"obsolete S100 alpha biosynthetic process (obsolete GO:0048153)","synonyms":[{"name":"S100 alpha anabolism","type":"exact"},{"name":"S100 alpha biosynthesis","type":"exact"},{"name":"S100 alpha formation","type":"exact"},{"name":"S100 alpha synthesis","type":"exact"}],"termid":"GO:0048153"}


id: PBO:0087764
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of TORC2 membrane-associated complex; involved in regulation of cell cycle-dependent actin cytoskeletal dynamics during polarized growth and cell wall integrity; BIT61 has a paralog, BIT2, that arose from the whole genome duplication","termid":"PBO:0087764"}


id: MONDO:0001440
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"keratoconjunctivitis","termid":"MONDO:0004768"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"neurotrophic keratoconjunctivitis","secondary_identifiers":["UMLS:C0155084","MEDGEN:509777","DOID:12125","SCTID:77080005","ICD9:370.35"],"termid":"MONDO:0001440","xrefs":{"Monarch":{"xref_id":"0001440"}}}


id: PBO:0055046
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2461","termid":"PBO:0055046"}


id: PBO:0047733
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"formin binding protein 1 pseudogene 2","termid":"PBO:0047733"}


id: SO:0000261
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A tRNA sequence that has a glycine anticodon, and a 3' glycine binding region.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"derives_from","term_name":"glycine_tRNA_primary_transcript","termid":"SO:0000218"},{"relation_name":"is_a","term_name":"tRNA","termid":"SO:0000253"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glycyl_tRNA","synonyms":[{"name":"glycyl tRNA","type":"exact"},{"name":"glycyl-transfer RNA","type":"related"},{"name":"glycyl-transfer ribonucleic acid","type":"related"}],"termid":"SO:0000261"}


id: MONDO:0032582
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"familial nephrotic syndrome","termid":"MONDO:0002350"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240"],"is_obsolete":false,"name":"nephrotic syndrome, type 19","secondary_identifiers":["OMIM:618178","MEDGEN:1648305","UMLS:C4748552","DOID:0080394","GARD:16301"],"synonyms":[{"name":"NEPHROTIC SYNDROME, TYPE 19","type":"related"},{"name":"NPHS19","type":"related"}],"termid":"MONDO:0032582","xrefs":{"Monarch":{"xref_id":"0032582"}}}


id: GO:1902102
data:
  {"annotated_genes":["SJAG_01515","SJAG_04259","SJAG_01837","SJAG_00145","SJAG_01330","SJAG_04126","SJAG_03327","SJAG_01082"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[105867,114095],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905318"},{"annotations":[77147,116273],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033316"},{"annotations":[98199],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1902103"},{"annotations":[113380],"is_not":false,"rel_names":["positively_regulates","regulates","is_a"],"summary":null,"term":"GO:1905326"},{"annotations":[94655],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905191"},{"annotations":[100863],"is_not":false,"rel_names":["regulates","is_a"],"summary":null,"term":"GO:1905325"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle.","definition_xrefs":["GOC:mtg_cell_cycle","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of meiotic cell cycle phase transition","termid":"GO:1901993"},{"relation_name":"is_a","term_name":"regulation of metaphase/anaphase transition of cell cycle","termid":"GO:1902099"},{"relation_name":"is_a","term_name":"regulation of meiotic chromosome separation","termid":"GO:1905132"},{"relation_name":"regulates","term_name":"metaphase/anaphase transition of meiotic cell cycle","termid":"GO:0044785"}],"gene_count":8,"genes_by_uniquename":{"SJAG_00145":null,"SJAG_01082":null,"SJAG_01330":null,"SJAG_01515":null,"SJAG_01837":null,"SJAG_03327":null,"SJAG_04126":null,"SJAG_04259":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0007049"],"is_obsolete":false,"name":"regulation of metaphase/anaphase transition of meiotic cell cycle","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"regulation of meiotic metaphase/anaphase transition","type":"exact"}],"termid":"GO:1902102","terms_by_termid":{"GO:0033316":null,"GO:1902103":null,"GO:1905191":null,"GO:1905318":null,"GO:1905325":null,"GO:1905326":null}}


id: GO:0051569
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3.","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of histone H3-K4 methylation (obsolete GO:0051569)","termid":"GO:0051569"}


id: MONDO:0020719
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete susceptibility to Hirschsprung disease (obsolete MONDO:0020719)","synonyms":[{"name":"HSCR","type":"related"}],"termid":"MONDO:0020719","xrefs":{"Monarch":{"xref_id":"0020719"}}}


id: PBO:0058541
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 6086","termid":"PBO:0058541"}


id: PBO:0058204
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4497","termid":"PBO:0058204"}


id: GO:0030820
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of cAMP catabolic process (obsolete GO:0030820)","synonyms":[{"name":"regulation of 3',5' cAMP catabolic process","type":"exact"},{"name":"regulation of 3',5' cAMP catabolism","type":"exact"},{"name":"regulation of 3',5'-cAMP catabolic process","type":"exact"},{"name":"regulation of 3',5'-cAMP catabolism","type":"exact"},{"name":"regulation of adenosine 3',5'-cyclophosphate catabolic process","type":"exact"},{"name":"regulation of adenosine 3',5'-cyclophosphate catabolism","type":"exact"},{"name":"regulation of cAMP breakdown","type":"exact"},{"name":"regulation of cAMP catabolism","type":"exact"},{"name":"regulation of cAMP degradation","type":"exact"},{"name":"regulation of cyclic AMP catabolic process","type":"exact"},{"name":"regulation of cyclic AMP catabolism","type":"exact"}],"termid":"GO:0030820"}


id: PBO:0085019
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Nicotinamide riboside kinase; catalyzes the phosphorylation of nicotinamide riboside and nicotinic acid riboside in salvage pathways for NAD+ biosynthesis","termid":"PBO:0085019"}


id: GO:0007507
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.","definition_xrefs":["GOC:jid","UBERON:0000948"],"direct_ancestors":[{"relation_name":"is_a","term_name":"animal organ development","termid":"GO:0048513"},{"relation_name":"part_of","term_name":"circulatory system development","termid":"GO:0072359"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"heart development","secondary_identifiers":["GO:0007511","Wikipedia:Heart_development"],"synonyms":[{"name":"cardiac development","type":"related"},{"name":"dorsal vessel development","type":"narrow"}],"termid":"GO:0007507"}


id: GO:0032691
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 beta production.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of interleukin-1 beta production","termid":"GO:0032651"},{"relation_name":"is_a","term_name":"negative regulation of interleukin-1 production","termid":"GO:0032692"},{"relation_name":"negatively_regulates","term_name":"interleukin-1 beta production","termid":"GO:0032611"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"negatively_regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"negative regulation of interleukin-1 beta production","secondary_identifiers":["GO:0050713","GO:0050724"],"synonyms":[{"name":"down regulation of interleukin-1 beta production","type":"exact"},{"name":"down-regulation of interleukin-1 beta production","type":"exact"},{"name":"downregulation of interleukin-1 beta production","type":"exact"},{"name":"inhibition of interleukin-1 beta production","type":"narrow"},{"name":"negative regulation of IL-1 beta production","type":"exact"},{"name":"negative regulation of interleukin-1 beta biosynthetic process","type":"narrow"},{"name":"negative regulation of interleukin-1 beta secretion","type":"narrow"}],"termid":"GO:0032691"}


id: GO:0006919
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process.","definition_xrefs":["PMID:18328827","GOC:mtg_apoptosis","Wikipedia:Caspase","GOC:jl","GOC:tb","GOC:al","GOC:dph","PMID:14744432"],"gene_count":0,"genotype_count":0,"name":"obsolete activation of cysteine-type endopeptidase activity involved in apoptotic process (obsolete GO:0006919)","secondary_identifiers":["Reactome:R-HSA-69416"],"synonyms":[{"name":"activation of caspase activity","type":"narrow"},{"name":"activation of metacaspase activity","type":"narrow"},{"name":"caspase activation","type":"exact"}],"termid":"GO:0006919"}


id: MONDO:0009115
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Congenital lactase deficiency is a rare severe gastrointestinal disorder in newborns primarily reported in Finland and characterized clinically by watery diarrhea on feeding with breast-milk or lactose-containing formula.","definition_xrefs":["Orphanet:53690"],"direct_ancestors":[{"relation_name":"is_a","term_name":"disorder of carbohydrate transmembrane transport and absorption","termid":"MONDO:0017706"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0037792"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0037792"],"is_obsolete":false,"name":"congenital lactase deficiency","secondary_identifiers":["ICD10CM:E73.0","DOID:0111646","MEDGEN:120617","OMIM:223000","GARD:12311","icd11.foundation:2109252471","UMLS:C0268179","MESH:C562600","SCTID:5388008","ICD9:271.3"],"synonyms":[{"name":"Alactasia, congenital","type":"related"},{"name":"congenital lactase deficiency","type":"exact"},{"name":"disaccharide intolerance 2","type":"related"},{"name":"lactase deficiency, congenital","type":"related"}],"termid":"MONDO:0009115","xrefs":{"Monarch":{"xref_id":"0009115"}}}


id: MONDO:0001905
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"tenosynovitis","termid":"MONDO:0004855"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0005336"],"is_obsolete":false,"name":"bicipital tenosynovitis","secondary_identifiers":["DOID:14192","ICD9:726.12","UMLS:C0158304","icd11.foundation:1292787411","SCTID:41137001","MEDGEN:510505"],"termid":"MONDO:0001905","xrefs":{"Monarch":{"xref_id":"0001905"}}}


id: GO:0047929
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: D-gluconate = 2-dehydro-3-deoxy-D-gluconate + H2O.","definition_xrefs":["EC:4.2.1.39","RHEA:21612"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydro-lyase activity","termid":"GO:0016836"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016829"],"is_obsolete":false,"name":"gluconate dehydratase activity","secondary_identifiers":["KEGG_REACTION:R01538","MetaCyc:GLUCONATE-DEHYDRATASE-RXN"],"synonyms":[{"name":"D-gluconate dehydratase activity","type":"related"},{"name":"D-gluconate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming)","type":"related"},{"name":"D-gluconate hydro-lyase activity","type":"related"}],"termid":"GO:0047929"}


id: GO:1901627
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic membrane organization.","definition_xrefs":["PMID:22426000","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of postsynaptic membrane organization","termid":"GO:1901626"},{"relation_name":"is_a","term_name":"negative regulation of synapse organization","termid":"GO:1905809"},{"relation_name":"negatively_regulates","term_name":"postsynaptic membrane organization","termid":"GO:0001941"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0061024"},{"rel_name":"negatively_regulates","termid":"GO:0061024"}],"interesting_parent_ids":["GO:0061024","GO:0008150"],"is_obsolete":false,"name":"negative regulation of postsynaptic membrane organization","synonyms":[{"name":"down regulation of postsynaptic membrane organisation","type":"exact"},{"name":"down regulation of postsynaptic membrane organization","type":"exact"},{"name":"down-regulation of postsynaptic membrane organisation","type":"exact"},{"name":"down-regulation of postsynaptic membrane organization","type":"exact"},{"name":"downregulation of postsynaptic membrane organisation","type":"exact"},{"name":"downregulation of postsynaptic membrane organization","type":"exact"},{"name":"inhibition of postsynaptic membrane organisation","type":"narrow"},{"name":"inhibition of postsynaptic membrane organization","type":"narrow"},{"name":"negative regulation of post-synaptic membrane organization","type":"exact"},{"name":"negative regulation of postsynaptic membrane organisation","type":"exact"}],"termid":"GO:1901627"}


id: PBO:0081530
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 440","termid":"PBO:0081530"}


id: PBO:0055583
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 3019","termid":"PBO:0055583"}


id: GO:0103010
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: gibberellin A53 + 2-oxoglutarate + O2 = gibberellin A97 + succinate + carbon dioxide.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete gibberellin A53,2-oxoglutarate:oxygen oxidoreductase activity (GA97-forming) (obsolete GO:0103010)","termid":"GO:0103010"}


id: GO:0009671
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nitrate(out) + H+(out) = nitrate(in) + H+(in).","definition_xrefs":["PMID:1990981","GOC:mah","PMID:10066586"],"direct_ancestors":[{"relation_name":"is_a","term_name":"solute:proton symporter activity","termid":"GO:0015295"},{"relation_name":"is_a","term_name":"high-affinity secondary active nitrite transmembrane transporter activity","termid":"GO:0015513"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0005215","GO:0022857","GO:0003674"],"is_obsolete":false,"name":"nitrate:proton symporter activity","synonyms":[{"name":"nitrate(chlorate):hydrogen symporter activity","type":"exact"},{"name":"nitrate(chlorate):proton symporter activity","type":"exact"},{"name":"nitrate:hydrogen symporter activity","type":"exact"}],"termid":"GO:0009671"}


id: PBO:0086847
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative quinone oxidoreductase; overexpression improves ethanol production and acid stress resistance; involved in copper metabolism; similar to Cochliobolus carbonum toxD gene","termid":"PBO:0086847"}


id: GO:1902871
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of amacrine cell differentiation.","definition_xrefs":["GO_REF:0000058","GOC:mr","GOC:TermGenie","PMID:16872597"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of neuron differentiation","termid":"GO:0045666"},{"relation_name":"is_a","term_name":"regulation of amacrine cell differentiation","termid":"GO:1902869"},{"relation_name":"positively_regulates","term_name":"amacrine cell differentiation","termid":"GO:0035881"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of amacrine cell differentiation","synonyms":[{"name":"activation of amacrine cell differentiation","type":"narrow"},{"name":"activation of amacrine neuron differentiation","type":"narrow"},{"name":"positive regulation of amacrine neuron differentiation","type":"exact"},{"name":"up regulation of amacrine cell differentiation","type":"exact"},{"name":"up regulation of amacrine neuron differentiation","type":"exact"},{"name":"up-regulation of amacrine cell differentiation","type":"exact"},{"name":"up-regulation of amacrine neuron differentiation","type":"exact"},{"name":"upregulation of amacrine cell differentiation","type":"exact"},{"name":"upregulation of amacrine neuron differentiation","type":"exact"}],"termid":"GO:1902871"}


id: GO:1904717
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of AMPA glutamate receptor clustering.","definition_xrefs":["GOC:hjd","GOC:TermGenie","PMID:21558424","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of glutamate receptor clustering","termid":"GO:0106104"},{"relation_name":"regulates","term_name":"AMPA glutamate receptor clustering","termid":"GO:0097113"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of AMPA glutamate receptor clustering","synonyms":[{"name":"regulation of AMPA receptor clustering","type":"exact"},{"name":"regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering","type":"exact"}],"termid":"GO:1904717"}


id: MONDO:0003513
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A mature or immature teratoma that arises from the stomach.","definition_xrefs":["NCIT:C5259"],"direct_ancestors":[{"relation_name":"is_a","term_name":"teratoma","termid":"MONDO:0002601"},{"relation_name":"is_a","term_name":"gastric neoplasm","termid":"MONDO:0021085"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"gastric teratoma","secondary_identifiers":["DOID:5561","MEDGEN:272665","UMLS:C1333790"],"synonyms":[{"name":"gastric teratoma","type":"exact"},{"name":"stomach teratoma","type":"exact"},{"name":"teratoma of stomach","type":"exact"},{"name":"teratoma of the stomach","type":"exact"}],"termid":"MONDO:0003513","xrefs":{"Monarch":{"xref_id":"0003513"}}}


id: MONDO:0002724
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A heterogeneous group of disorders characterized by the abnormal growth and accumulation of mast cells in one or more organ systems. Recent data suggest that most variants of mast cell neoplasms are clonal disorders. (WHO, 2001)","definition_xrefs":["NCIT:C9295"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myeloid neoplasm","termid":"MONDO:0005170"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"mast cell neoplasm","secondary_identifiers":["UMLS:C0334664","ICD9:238.79","MEDGEN:83178","DOID:3664","EFO:0009000","SCTID:414653009"],"synonyms":[{"name":"Mast cell proliferative disease","type":"exact"},{"name":"Mast cell tumor","type":"exact"},{"name":"Mast cell tumour","type":"exact"},{"name":"mast cell neoplasm","type":"exact"},{"name":"mast cell tumor","type":"exact"},{"name":"mast cell tumour","type":"exact"},{"name":"neoplasm of Mast cells","type":"exact"},{"name":"neoplasm of the Mast cells","type":"exact"},{"name":"tumor of Mast cells","type":"exact"},{"name":"tumor of the Mast cells","type":"exact"},{"name":"tumour of Mast cells","type":"exact"},{"name":"tumour of the Mast cells","type":"exact"}],"termid":"MONDO:0002724","xrefs":{"Monarch":{"xref_id":"0002724"}}}


id: MONDO:0009180
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Junctional epidermolysis bullosa, non-Herlitz (JEB-nH) is a subtype of junctional epidermolysis bullosa (JEB) characterized by the presence of skin and mucosal blistering, nail dystrophy or nail absence and enamel hypoplasia.","definition_xrefs":["Orphanet:89840"],"direct_ancestors":[{"relation_name":"is_a","term_name":"junctional epidermolysis bullosa","termid":"MONDO:0017612"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"junctional epidermolysis bullosa, non-Herlitz type","secondary_identifiers":["NANDO:1201066","OMIM:226650","MEDGEN:82798","NANDO:2201379","UMLS:C0268374","SCTID:33662006","ICD9:757.39"],"synonyms":[{"name":"JEB-I","type":"related"},{"name":"JEB-nH","type":"related"},{"name":"JEN-nH","type":"exact"},{"name":"epidermolysis bullosa Junctionalis, Disentis type","type":"related"},{"name":"epidermolysis bullosa Junctionalis, non-Herlitz type","type":"related"},{"name":"epidermolysis bullosa Junctionalis, progressive","type":"related"},{"name":"epidermolysis bullosa Junctionalis, severe Nonlethal","type":"related"},{"name":"epidermolysis bullosa, generalised atrophic benign","type":"related"},{"name":"epidermolysis bullosa, generalized atrophic benign","type":"related"},{"name":"epidermolysis bullosa, junctional, Localisata variant","type":"related"},{"name":"epidermolysis bullosa, junctional, non-Herlitz type","type":"related"},{"name":"junctional epidermolysis bullosa inversa","type":"related"}],"termid":"MONDO:0009180","xrefs":{"Monarch":{"xref_id":"0009180"}}}


id: MONDO:0019036
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Free-living amebae belonging to the genera Acanthamoeba, Balamuthia, Naegleria and Sappinia are important causes of disease in humans and animals. Naegleria fowleri produces an acute, and usually lethal, central nervous system (CNS) disease called primary amebic meningoencephalitis (PAM). Acanthamoeba spp. and Balamuthia mandrillaris are opportunistic free-living amebae capable of causing granulomatous amebic encephalitis (GAE) in individuals with compromised immune systems. Sappinia pedata has been implicated in a case of amebic encephalitis. Naegleria fowleri and Acanthamoeba spp., are commonly found in lakes, swimming pools, tap water, and heating and air conditioning units.","direct_ancestors":[{"relation_name":"is_a","term_name":"parasitic infectious disease","termid":"MONDO:0005135"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"amoebiasis due to free-living amoebae","secondary_identifiers":["MEDGEN:509253","Orphanet:68","GARD:12650","UMLS:C0153326"],"termid":"MONDO:0019036","xrefs":{"Monarch":{"xref_id":"0019036"}}}


id: MONDO:0034109
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive disease","termid":"MONDO:0006025"},{"relation_name":"is_a","term_name":"congenital myopathy","termid":"MONDO:0019952"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0005336"],"is_obsolete":false,"name":"congenital myopathy with reduced type 2 muscle fibers","secondary_identifiers":["GARD:17989","DOID:0081346","MEDGEN:1672638","OMIM:618414","Orphanet:544602","UMLS:C5193081"],"synonyms":[{"name":"myopathy, congenital, with fast-twitch (type II) fiber atrophy","type":"exact"},{"name":"myopathy, congenital, with fast-twitch (type II) fibre atrophy","type":"exact"}],"termid":"MONDO:0034109","xrefs":{"Monarch":{"xref_id":"0034109"}}}


id: PBO:0071210
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L23a pseudogene 51","termid":"PBO:0071210"}


id: GO:0046623
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the movement of a sphingolipid from the cytosolic to the exoplasmic leaflet of a membrane, using energy from the hydrolysis of ATP.","definition_xrefs":["GOC:ai","PMID:12034738"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sphingolipid transporter activity","termid":"GO:0046624"},{"relation_name":"is_a","term_name":"floppase activity","termid":"GO:0140328"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0140303"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0140303","GO:0005215","GO:0003674"],"is_obsolete":false,"name":"sphingolipid floppase activity","synonyms":[{"name":"sphingolipid flippase activity","type":"exact"},{"name":"sphingolipid floppase activity (cytosolic to exoplasmic leaflet)","type":"exact"},{"name":"sphingolipid-translocating ATPase activity","type":"related"}],"termid":"GO:0046623"}


id: PBO:0039039
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"AGBL1 antisense RNA 1","termid":"PBO:0039039"}


id: SO:0001487
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"The status of a whole genome sequence, where overall coverage represents at least 90 percent of the genome.","definition_xrefs":["DOI:10.1126"],"direct_ancestors":[{"relation_name":"is_a","term_name":"whole_genome_sequence_status","termid":"SO:0001499"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"high_quality_draft","synonyms":[{"name":"high quality draft","type":"exact"}],"termid":"SO:0001487"}


id: PBO:0059015
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"matrix metallopeptidase 2","termid":"PBO:0059015"}


id: PBO:0050228
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"high mobility group nucleosomal binding domain 2 pseudogene 6","termid":"PBO:0050228"}


id: PBO:0071038
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L21 pseudogene 40","termid":"PBO:0071038"}


id: PBO:0063416
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PDE2A antisense RNA 1","termid":"PBO:0063416"}


id: PBO:0048935
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"golgi transport 1B","termid":"PBO:0048935"}


id: MONDO:1011119
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hypogonadism that occurs in deer.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hypogonadism, non-human animal","termid":"MONDO:1010276"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hypogonadism, deer","secondary_identifiers":["OMIA:000522-9850"],"termid":"MONDO:1011119","xrefs":{"Monarch":{"xref_id":"1011119"}}}


id: PBO:0000459
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"exosome subunit Rrp4 (predicted)","termid":"PBO:0000459"}


id: RO:0002109
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"Relation between a muscle and a motor neuron that synapses to it via a type Ib bouton.","direct_ancestors":[{"relation_name":"is_a","term_name":"synapsed_by","termid":"RO:0002103"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"synapsed_by_via_type_Ib_bouton","termid":"RO:0002109"}


id: GO:0043031
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of leukocyte activation","termid":"GO:0002695"},{"relation_name":"is_a","term_name":"regulation of macrophage activation","termid":"GO:0043030"},{"relation_name":"negatively_regulates","term_name":"macrophage activation","termid":"GO:0042116"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of macrophage activation","synonyms":[{"name":"down regulation of macrophage activation","type":"exact"},{"name":"down-regulation of macrophage activation","type":"exact"},{"name":"downregulation of macrophage activation","type":"exact"},{"name":"inhibition of macrophage activation","type":"narrow"},{"name":"negative regulation of macrophage polarization","type":"exact"}],"termid":"GO:0043031"}


id: PBO:0108511
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Clr6 and Rpd3L histone deacetylase complex subunit Sds3","termid":"PBO:0108511"}


id: PBO:0044936
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"deoxyguanosine kinase","termid":"PBO:0044936"}


id: PBO:0053809
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1068","termid":"PBO:0053809"}


id: GO:0033668
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a symbiont inhibits or disrupts the normal execution of host apoptosis, leading to a decrease in the frequency, rate or extent of apoptosis in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated suppression of host programmed cell death","termid":"GO:0052041"},{"relation_name":"is_a","term_name":"symbiont-mediated perturbation of host apoptosis","termid":"GO:0052150"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"symbiont-mediated suppression of host apoptosis","secondary_identifiers":["Reactome:R-HSA-9635465","GO:0039650"],"synonyms":[{"name":"down regulation by organism of host apoptotic programmed cell death","type":"exact"},{"name":"down-regulation by organism of host apoptotic programmed cell death","type":"exact"},{"name":"downregulation by organism of host apoptotic programmed cell death","type":"exact"},{"name":"inhibition by organism of host apoptotic programmed cell death","type":"exact"},{"name":"negative regulation by symbiont of host apoptosis","type":"exact"},{"name":"negative regulation by symbiont of host apoptotic process","type":"exact"},{"name":"negative regulation by virus of host apoptosis","type":"narrow"},{"name":"suppression by symbiont of host apoptotic process","type":"exact"},{"name":"suppression by virus of host apoptosis","type":"narrow"}],"termid":"GO:0033668"}


id: SO:0000296
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A region of nucleic acid from which replication initiates; includes sequences that are recognized by replication proteins, the site from which the first separation of complementary strands occurs, and specific replication start sites.","definition_xrefs":["NCBI:cf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"biological_region","termid":"SO:0001411"},{"relation_name":"part_of","term_name":"replicon","termid":"SO:0001235"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"origin_of_replication","secondary_identifiers":["http://en.wikipedia.org/wiki/Origin_of_replication"],"synonyms":[{"name":"INSDC_feature:rep_origin","type":"exact"},{"name":"ori","type":"exact"},{"name":"origin of replication","type":"exact"}],"termid":"SO:0000296"}


id: GO:0071641
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of chemokine production","termid":"GO:0032682"},{"relation_name":"is_a","term_name":"regulation of macrophage inflammatory protein 1 alpha production","termid":"GO:0071640"},{"relation_name":"negatively_regulates","term_name":"macrophage inflammatory protein-1 alpha production","termid":"GO:0071608"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"negative regulation of macrophage inflammatory protein 1 alpha production","synonyms":[{"name":"negative regulation of CCL3 production","type":"exact"},{"name":"negative regulation of MIP-1a production","type":"exact"},{"name":"negative regulation of chemokine (C-C motif) ligand 3 production","type":"exact"},{"name":"negative regulation of macrophage inflammatory protein production","type":"broad"}],"termid":"GO:0071641"}


id: FYPO:0003607
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype in which the size, shape, or structure of the mitotic or meiotic spindle is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal spindle","termid":"FYPO:0000120"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0002399"},{"rel_name":"is_a","termid":"FYPO:0000120"},{"rel_name":"output_of","termid":"FYPO:0000054"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0002399","FYPO:0001985","FYPO:0000054","FYPO:0005447","FYPO:0000120"],"is_obsolete":false,"name":"abnormal spindle morphology","synonyms":[{"name":"spindle morphology: abnormal","type":"related"}],"termid":"FYPO:0003607"}


id: MONDO:0019520
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. A lymphedema that is part of a larger syndrome.","definition_xrefs":["MONDO:patterns/syndromic"],"gene_count":0,"genotype_count":0,"name":"obsolete syndromic lymphedema (obsolete MONDO:0019520)","secondary_identifiers":["Orphanet:89832"],"synonyms":[{"name":"syndrome associated with lymphedema","type":"exact"},{"name":"syndromic lymphedema","type":"exact"}],"termid":"MONDO:0019520","xrefs":{"Monarch":{"xref_id":"0019520"}}}


id: PBO:0005901
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA Tyrosine, mitochondrial","termid":"PBO:0005901"}


id: PBO:0000908
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA-directed RNA polymerase Rdp1","termid":"PBO:0000908"}


id: GO:0009202
data:
  {"annotated_genes":["SJAG_00885"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[106810],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009216"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar.","definition_xrefs":["GOC:go_curators","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleoside triphosphate biosynthetic process","termid":"GO:0009142"},{"relation_name":"is_a","term_name":"deoxyribonucleoside triphosphate metabolic process","termid":"GO:0009200"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00885":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0055086"}],"interesting_parent_ids":["GO:0055086","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"deoxyribonucleoside triphosphate biosynthetic process","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"deoxyribonucleoside triphosphate anabolism","type":"exact"},{"name":"deoxyribonucleoside triphosphate biosynthesis","type":"exact"},{"name":"deoxyribonucleoside triphosphate formation","type":"exact"},{"name":"deoxyribonucleoside triphosphate synthesis","type":"exact"}],"termid":"GO:0009202","terms_by_termid":{"GO:0009216":null}}


id: MONDO:0015033
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hereditary cerebral hemorrhage with amyloidosis, Dutch type (HCHWA-D) is a form of HCHWA, a group of familial central nervous system disorders, characterized by severe cerebral amyloid angiopathy (CAA), hemorrhagic and non-hemorrhagic strokes and dementia.","definition_xrefs":["Orphanet:100006"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cerebral amyloid angiopathy, APP-related","termid":"MONDO:0011583"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0021179"}],"interesting_parent_ids":["MONDO:0021179","MONDO:0005066"],"is_obsolete":false,"name":"ABeta amyloidosis, dutch type","secondary_identifiers":["ICD9:277.39","MEDGEN:419468","SCTID:56453003","UMLS:C2931672","ICD10EXP:E85.4+","ICD10EXP:I68.0*","GARD:16929"],"synonyms":[{"name":"ABetaE22Q amyloidosis","type":"exact"},{"name":"HCHWA, Dutch type","type":"exact"},{"name":"HCHWA-D","type":"exact"},{"name":"cerebral amyloid angiopathy, APP-related, Dutch variant","type":"exact"},{"name":"hereditary cerebral haemorrhage with amyloidosis, Dutch type","type":"exact"},{"name":"hereditary cerebral hemorrhage with amyloidosis, Dutch type","type":"exact"}],"termid":"MONDO:0015033","xrefs":{"Monarch":{"xref_id":"0015033"}}}


id: GO:0047440
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2-dehydro-3-deoxy-D-arabinonate = glycolaldehyde + pyruvate.","definition_xrefs":["RHEA:20609","EC:4.1.2.28"],"direct_ancestors":[{"relation_name":"is_a","term_name":"aldehyde-lyase activity","termid":"GO:0016832"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016829","GO:0003674"],"is_obsolete":false,"name":"2-dehydro-3-deoxy-D-pentonate aldolase activity","secondary_identifiers":["MetaCyc:4.1.2.28-RXN","KEGG_REACTION:R01782"],"synonyms":[{"name":"2-dehydro-3-deoxy-D-pentonate glycolaldehyde-lyase activity","type":"related"},{"name":"2-keto-3-deoxy-D-pentonate aldolase activity","type":"related"},{"name":"3-deoxy-D-pentulosonic acid aldolase","type":"broad"}],"termid":"GO:0047440"}


id: GO:0097353
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The regionalization process in which the areas along the centrolateral axis are established that will lead to differences in cell differentiation, or in which cells interpret a specific environment.","definition_xrefs":["GOC:dsz"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regionalization","termid":"GO:0003002"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"centrolateral pattern formation","synonyms":[{"name":"mediolateral pattern formation","type":"exact"}],"termid":"GO:0097353"}


id: PBO:0090121
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial protease Sdd3","termid":"PBO:0090121"}


id: PBO:0016561
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by Giardia lamblia single peptide cis-prenyltransferase","termid":"PBO:0016561"}


id: PBO:0081506
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 410","termid":"PBO:0081506"}


id: PBO:0036319
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"human NEDD4 family-interacting protein ortholog (predicted)","termid":"PBO:0036319"}


id: MONDO:0009699
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Action myoclonus-renal failure syndrome (AMRF) is a rare epilepsy syndrome characterized by progressive myoclonus epilepsy in association with primary glomerular disease. Patients present with neurologic symptoms (including tremor, action myoclonus, tonic-clonic seizures, later ataxia and dysarthria) that may precede, occur simultaneously or be followed by renal manifestations including proteinuria that progresses to nephrotic syndrome and end-stage renal disease. In some patients, sensorimotor peripheral neuropathy, sensorineural hearing loss and dilated cardiomyopathy are associated symptoms.","definition_xrefs":["Orphanet:163696"],"direct_ancestors":[{"relation_name":"is_a","term_name":"progressive myoclonus epilepsy","termid":"MONDO:0020074"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027"],"is_obsolete":false,"name":"action myoclonus-renal failure syndrome","secondary_identifiers":["DOID:0111444","GARD:17000","SCTID:764453009","UMLS:C0751779","MEDGEN:155629","OMIM:254900"],"synonyms":[{"name":"AMRF","type":"exact"},{"name":"EPM4","type":"exact"},{"name":"action myoclonus-renal failure syndrome","type":"exact"},{"name":"epilepsy, progressive myoclonic 4, with or without renal failure","type":"exact"},{"name":"epilepsy, progressive myoclonic, 4, with or without renal failure","type":"exact"},{"name":"myoclonus-nephropathy syndrome","type":"exact"},{"name":"progressive myoclonic epilepsy type 4","type":"exact"}],"termid":"MONDO:0009699","xrefs":{"Monarch":{"xref_id":"0009699"}}}


id: MONDO:0016677
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.","definition_xrefs":["MESH:D000014"],"direct_ancestors":[{"relation_name":"is_a","term_name":"developmental defect during embryogenesis","termid":"MONDO:0019755"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"toxic or drug-related embryofetopathy","secondary_identifiers":["Orphanet:251529","UMLS:C5680710","MEDGEN:1843068","icd11.foundation:293076727"],"termid":"MONDO:0016677","xrefs":{"Monarch":{"xref_id":"0016677"}}}


id: MONDO:1010754
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hereditary sparse hair and dental aplasia in dogs associated with a variation in the EDA gene.","definition_xrefs":["OMIA:000543-9615"],"direct_ancestors":[{"relation_name":"is_a","term_name":"X-linked disease, non-human animal","termid":"MONDO:1012575"},{"relation_name":"is_a","term_name":"hypohidrotic ectodermal dysplasia, non-human animal","termid":"MONDO:1012576"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"X-linked hypohidrotic ectodermal dysplasia, EDA-related, dog","termid":"MONDO:1010754","xrefs":{"Monarch":{"xref_id":"1010754"}}}


id: PBO:0055729
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"LIM domain only 3","termid":"PBO:0055729"}


id: GO:0015486
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (glycoside, pentoside or hexuronide)(out) + monovalent cation(out) = (glycoside, pentoside or hexuronide)(in) + monovalent cation(in). The cation is Na+, Li+ or H+.","definition_xrefs":["TC:2.A.2.-.-"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbohydrate:monoatomic cation symporter activity","termid":"GO:0005402"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0005215","GO:0022857","GO:0003674"],"is_obsolete":false,"name":"glycoside-pentoside-hexuronide:cation symporter activity","termid":"GO:0015486"}


id: GO:0033574
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.","definition_xrefs":["GOC:sl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to lipid","termid":"GO:0033993"},{"relation_name":"is_a","term_name":"response to ketone","termid":"GO:1901654"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to testosterone","synonyms":[{"name":"response to testosterone stimulus","type":"exact"}],"termid":"GO:0033574"}


id: PBO:0079214
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"testis specific serine kinase 6","termid":"PBO:0079214"}


id: MONDO:0016725
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete pineal parenchymal tumor of intermediate differenciation (obsolete MONDO:0016725)","termid":"MONDO:0016725","xrefs":{"Monarch":{"xref_id":"0016725"}}}


id: PBO:0031352
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_cellular_respiration","termid":"PBO:0031352"}


id: GO:0061554
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure formation involved in morphogenesis","termid":"GO:0048646"},{"relation_name":"part_of","term_name":"ganglion morphogenesis","termid":"GO:0061552"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"ganglion formation","synonyms":[{"name":"ganglia formation","type":"related"}],"termid":"GO:0061554"}


