# terms

id: GO:0004677
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"DNA dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein serine/threonine kinase activity","termid":"GO:0004674"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0004672"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016301"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0140096"}],"interesting_parent_ids":["GO:0004672","GO:0003674","GO:0003824","GO:0140096","GO:0016740","GO:0016301"],"is_obsolete":false,"name":"DNA-dependent protein kinase activity","termid":"GO:0004677"}


id: GO:0070019
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. A receptor complex that consists of two transforming growth factor beta (TGF-beta) type II receptor monomers. TGF-beta type II receptor dimers form in the presence or absence of ligand, and upon ligand binding can associate with TGF-beta type I receptor dimers.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete transforming growth factor beta type II receptor homodimeric complex (obsolete GO:0070019)","synonyms":[{"name":"TGF-beta type II receptor complex","type":"exact"},{"name":"TGF-beta type II receptor dimer","type":"exact"},{"name":"TGFBR2 homodimer","type":"exact"},{"name":"transforming growth factor beta type II receptor complex","type":"exact"}],"termid":"GO:0070019"}


id: PBO:0064366
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PML nuclear body scaffold","termid":"PBO:0064366"}


id: GO:0005221
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transmembrane transfer of a monoatomic cation by a channel that opens when intracellular cyclic nucleotide has been bound by the channel complex or one of its constituent parts.","definition_xrefs":["GOC:mtg_transport"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracellularly ligand-gated monoatomic ion channel activity","termid":"GO:0005217"},{"relation_name":"is_a","term_name":"cyclic nucleotide-activated monoatomic ion channel activity","termid":"GO:0043855"},{"relation_name":"is_a","term_name":"ligand-gated monoatomic cation channel activity","termid":"GO:0099094"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0003674","GO:0005215","GO:0022857"],"is_obsolete":false,"name":"intracellularly cyclic nucleotide-activated monoatomic cation channel activity","secondary_identifiers":["Reactome:R-HSA-2514867"],"synonyms":[{"name":"intracellular cyclic nucleotide activated cation channel activity","type":"broad"},{"name":"intracellular cyclic nucleotide activated monoatomic cation channel activity","type":"exact"},{"name":"intracellular cyclic nucleotide-activated monoatomic cation channel activity","type":"exact"}],"termid":"GO:0005221"}


id: MONDO:0008841
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"ataxia telangiectasia","termid":"MONDO:0008840"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005047"},{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005559","MONDO:0005047","MONDO:0005046"],"is_obsolete":false,"name":"ataxia-telangiectasia with generalized skin pigmentation and early death","secondary_identifiers":["MESH:C565930","OMIM:208910","UMLS:C1859615","GARD:15141","MEDGEN:395306"],"synonyms":[{"name":"ataxia-telangiectasia with generalized skin pigmentation and early death","type":"exact"}],"termid":"MONDO:0008841","xrefs":{"Monarch":{"xref_id":"0008841"}}}


id: PBO:0061077
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NFKB repressing factor","termid":"PBO:0061077"}


id: PBO:0044221
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cortexin 2","termid":"PBO:0044221"}


id: GO:1905805
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The disaggregation of an excitatory synapse into its constituent components.","definition_xrefs":["PMID:27779093","GO_REF:0000079","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"synapse pruning","termid":"GO:0098883"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"excitatory synapse pruning","synonyms":[{"name":"synapse clearance","type":"broad"},{"name":"synapse disassembly","type":"broad"},{"name":"synapse elimination","type":"broad"},{"name":"synapse removal","type":"broad"}],"termid":"GO:1905805"}


id: GO:0044535
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: a very-long-chain 2,3-saturated fatty acyl-CoA + O2 = a very-long-chain (2E)-enoyl-CoA + H2O2.","definition_xrefs":["RHEA:78847","PMID:17458872"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acyl-CoA oxidase activity","termid":"GO:0003997"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"very-long-chain fatty acyl-CoA oxidase activity","synonyms":[{"name":"VLC fatty-acyl-CoA oxidase activity","type":"exact"},{"name":"very long chain fatty-acyl-CoA oxidase activity","type":"exact"},{"name":"very-long-chain acyl-CoA oxidase activity","type":"exact"}],"termid":"GO:0044535"}


id: PBO:0065366
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pleckstrin and Sec7 domain containing 2","termid":"PBO:0065366"}


id: GO:0070282
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to pyridoxine, 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol, a form of vitamin B6.","definition_xrefs":["CHEBI:16709","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vitamin B6 binding","termid":"GO:0070279"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0005488","GO:0003674"],"is_obsolete":false,"name":"pyridoxine binding","termid":"GO:0070282"}


id: PBO:0116430
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial F1-FO ATP synthase chaperone, Atp10","termid":"PBO:0116430"}


id: PBO:0114522
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"histone H3-H4 chaperone, CAF assembly factor (CAF-1) complex WD repeat subunit, Pcf2","termid":"PBO:0114522"}


id: PBO:0053906
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1198","termid":"PBO:0053906"}


id: GO:0046151
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"eye pigment metabolic process","termid":"GO:0042441"},{"relation_name":"is_a","term_name":"pigment catabolic process","termid":"GO:0046149"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"eye pigment catabolic process","synonyms":[{"name":"eye pigment breakdown","type":"exact"},{"name":"eye pigment catabolism","type":"exact"},{"name":"eye pigment degradation","type":"exact"}],"termid":"GO:0046151"}


id: MONDO:0002353
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign or malignant neoplasm that affects the glottic area of the larynx.","definition_xrefs":["NCIT:C4425"],"direct_ancestors":[{"relation_name":"is_a","term_name":"laryngeal neoplasm","termid":"MONDO:0021071"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glottis neoplasm","secondary_identifiers":["UMLS:C0345713","DOID:2597","MEDGEN:138026","SCTID:126693009"],"synonyms":[{"name":"glottis neoplasm","type":"exact"},{"name":"glottis neoplasm (disease)","type":"exact"},{"name":"glottis tumor","type":"exact"},{"name":"glottis tumour","type":"exact"},{"name":"neoplasm of glottis","type":"exact"},{"name":"neoplasm of the glottis","type":"exact"},{"name":"tumor of glottis","type":"exact"},{"name":"tumor of the glottis","type":"exact"},{"name":"tumour of glottis","type":"exact"},{"name":"tumour of the glottis","type":"exact"}],"termid":"MONDO:0002353","xrefs":{"Monarch":{"xref_id":"0002353"}}}


id: PBO:0040825
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bridging integrator 3","termid":"PBO:0040825"}


id: GO:0042919
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.","definition_xrefs":["GOC:jl","ISBN:0721662544"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monocarboxylic acid transport","termid":"GO:0015718"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810","GO:0051179"],"is_obsolete":false,"name":"benzoate transport","termid":"GO:0042919"}


id: PBO:0046024
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"eukaryotic translation initiation factor 2B subunit alpha","termid":"PBO:0046024"}


id: PBO:0040495
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aurora kinase A and ninein interacting protein","termid":"PBO:0040495"}


id: GO:0120279
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A small cytoplasmic, non-membranous RNA/protein complex aggregate in the primordial germ cells that are distinct from, but colocalize with or are adjacent to, P granules and mutator foci and are associated with RNA metabolism. Z granules have been observed in C. elegans.","definition_xrefs":["GOC:krc","PMID:32650583","GOC:dr","PMID:29769721","PMID:31378614"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytoplasmic ribonucleoprotein granule","termid":"GO:0036464"},{"relation_name":"part_of","term_name":"germ plasm","termid":"GO:0060293"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0005575","GO:0005737"],"is_obsolete":false,"name":"Z granule","synonyms":[{"name":"germline granule","type":"broad"}],"termid":"GO:0120279"}


id: GO:0016257
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The modification of high-mannose (Man9-Asn) N-glycans by mannosyl-oligosaccharide 1,2-alpha-mannosidase. This may result in Man8GlcNAc2-Asn N-glycans (which in yeast may be subsequently modified by the addition of further mannose residues) or Man5GlcNAc2-Asn N-glycans that are substrates for further diversification in the Golgi apparatus.","definition_xrefs":["ISBN:0879695595"],"direct_ancestors":[{"relation_name":"is_a","term_name":"N-glycan processing","termid":"GO:0006491"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"N-glycan processing to secreted and cell-surface N-glycans","termid":"GO:0016257"}


id: PATO:0000086
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000086 absolute sensitivity (obsolete PATO:0000086)","termid":"PATO:0000086"}


id: GO:1905118
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of ribonucleoside-diphosphate reductase activity.","definition_xrefs":["GOC:TermGenie","GO_REF:0000059","GOC:bhm","PMID:24733891"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of ribonucleoside-diphosphate reductase activity (obsolete GO:1905118)","synonyms":[{"name":"activation of RNR","type":"related"},{"name":"activation of adenosylcobalamin-dependent ribonucleotide reductase activity","type":"related"},{"name":"activation of aerobic non-heme iron-dependent ribonucleotide reductase activity","type":"related"},{"name":"activation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity","type":"related"},{"name":"activation of class I ribonucleotide reductase activity","type":"related"},{"name":"activation of class II ribonucleoside-diphosphate reductase activity","type":"related"},{"name":"activation of class II ribonucleotide reductase activity","type":"related"},{"name":"activation of class III ribonucleotide reductase activity","type":"related"},{"name":"activation of nucleoside diphosphate reductase activity","type":"related"},{"name":"activation of purine/pyrimidine nucleoside diphosphate reduction","type":"related"},{"name":"activation of ribonucleoside 5'-diphosphate reductase activity","type":"related"},{"name":"activation of ribonucleoside-diphosphate reductase activity","type":"related"},{"name":"activation of ribonucleotide diphosphate reductase activity","type":"related"},{"name":"positive regulation of RNR","type":"related"},{"name":"positive regulation of adenosylcobalamin-dependent ribonucleotide reductase activity","type":"related"},{"name":"positive regulation of aerobic non-heme iron-dependent ribonucleotide reductase activity","type":"related"},{"name":"positive regulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity","type":"related"},{"name":"positive regulation of class I ribonucleotide reductase activity","type":"related"},{"name":"positive regulation of class II ribonucleoside-diphosphate reductase activity","type":"related"},{"name":"positive regulation of class II ribonucleotide reductase activity","type":"related"},{"name":"positive regulation of class III ribonucleotide reductase activity","type":"related"},{"name":"positive regulation of nucleoside diphosphate reductase activity","type":"related"},{"name":"positive regulation of purine/pyrimidine nucleoside diphosphate reduction","type":"related"},{"name":"positive regulation of ribonucleoside 5'-diphosphate reductase activity","type":"related"},{"name":"positive regulation of ribonucleotide diphosphate reductase activity","type":"related"},{"name":"up regulation of RNR","type":"related"},{"name":"up regulation of adenosylcobalamin-dependent ribonucleotide reductase activity","type":"related"},{"name":"up regulation of aerobic non-heme iron-dependent ribonucleotide reductase activity","type":"related"},{"name":"up regulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity","type":"related"},{"name":"up regulation of class I ribonucleotide reductase activity","type":"related"},{"name":"up regulation of class II ribonucleoside-diphosphate reductase activity","type":"related"},{"name":"up regulation of class II ribonucleotide reductase activity","type":"related"},{"name":"up regulation of class III ribonucleotide reductase activity","type":"related"},{"name":"up regulation of nucleoside diphosphate reductase activity","type":"related"},{"name":"up regulation of purine/pyrimidine nucleoside diphosphate reduction","type":"related"},{"name":"up regulation of ribonucleoside 5'-diphosphate reductase activity","type":"related"},{"name":"up regulation of ribonucleoside-diphosphate reductase activity","type":"related"},{"name":"up regulation of ribonucleotide diphosphate reductase activity","type":"related"},{"name":"up-regulation of RNR","type":"related"},{"name":"up-regulation of adenosylcobalamin-dependent ribonucleotide reductase activity","type":"related"},{"name":"up-regulation of aerobic non-heme iron-dependent ribonucleotide reductase activity","type":"related"},{"name":"up-regulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity","type":"related"},{"name":"up-regulation of class I ribonucleotide reductase activity","type":"related"},{"name":"up-regulation of class II ribonucleoside-diphosphate reductase activity","type":"related"},{"name":"up-regulation of class II ribonucleotide reductase activity","type":"related"},{"name":"up-regulation of class III ribonucleotide reductase activity","type":"related"},{"name":"up-regulation of nucleoside diphosphate reductase activity","type":"related"},{"name":"up-regulation of purine/pyrimidine nucleoside diphosphate reduction","type":"related"},{"name":"up-regulation of ribonucleoside 5'-diphosphate reductase activity","type":"related"},{"name":"up-regulation of ribonucleoside-diphosphate reductase activity","type":"related"},{"name":"up-regulation of ribonucleotide diphosphate reductase activity","type":"related"},{"name":"upregulation of RNR","type":"related"},{"name":"upregulation of adenosylcobalamin-dependent ribonucleotide reductase activity","type":"related"},{"name":"upregulation of aerobic non-heme iron-dependent ribonucleotide reductase activity","type":"related"},{"name":"upregulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity","type":"related"},{"name":"upregulation of class I ribonucleotide reductase activity","type":"related"},{"name":"upregulation of class II ribonucleoside-diphosphate reductase activity","type":"related"},{"name":"upregulation of class II ribonucleotide reductase activity","type":"related"},{"name":"upregulation of class III ribonucleotide reductase activity","type":"related"},{"name":"upregulation of nucleoside diphosphate reductase activity","type":"related"},{"name":"upregulation of purine/pyrimidine nucleoside diphosphate reduction","type":"related"},{"name":"upregulation of ribonucleoside 5'-diphosphate reductase activity","type":"related"},{"name":"upregulation of ribonucleoside-diphosphate reductase activity","type":"related"},{"name":"upregulation of ribonucleotide diphosphate reductase activity","type":"related"}],"termid":"GO:1905118"}


id: GO:0035888
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: H+ + H2O + isoguanine = NH4+ + xanthine.","definition_xrefs":["RHEA:47720","PMID:21604715"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines","termid":"GO:0016814"},{"relation_name":"is_a","term_name":"deaminase activity","termid":"GO:0019239"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016810"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0016810","GO:0003674","GO:0016787"],"is_obsolete":false,"name":"isoguanine deaminase activity","secondary_identifiers":["MetaCyc:RXN0-6708"],"synonyms":[{"name":"2-hydroxyadenine deaminase activity","type":"exact"},{"name":"2-oxoadenine deaminase activity","type":"exact"}],"termid":"GO:0035888"}


id: GO:0052165
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process in which a symbiont modulates the frequency, rate or extent of production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06","PMID:6870275"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated evasion of host immune response","termid":"GO:0042783"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"symbiont-mediated perturbation of host phytoalexin production","secondary_identifiers":["GO:0052378","GO:0052304","GO:0052061","GO:0052549","GO:0052566","PMID:28805743"],"synonyms":[{"name":"evasion or tolerance by symbiont of host-produced phytoalexins","type":"exact"},{"name":"evasion or tolerance of phytoalexins","type":"exact"},{"name":"evasion or tolerance of phytoalexins produced by host in response to organism","type":"exact"},{"name":"host phytoalexin detoxification","type":"narrow"},{"name":"modulation by organism of phytoalexin production in other organism involved in symbiotic interaction","type":"narrow"},{"name":"modulation by symbiont of host phytoalexin production","type":"narrow"},{"name":"phytoalexin detoxification","type":"narrow"},{"name":"response to host phytoalexin production","type":"broad"},{"name":"response to phytoalexin production by other organism involved in symbiotic interaction","type":"broad"},{"name":"symbiont defense to host-produced phytoalexin","type":"exact"}],"termid":"GO:0052165"}


id: GO:0004243
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the release of an N-terminal octapeptide as second stage of processing of some proteins imported in the mitochondrion.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete mitochondrial intermediate peptidase activity (obsolete GO:0004243)","synonyms":[{"name":"MIP","type":"broad"},{"name":"mitochondrial intermediate peptidase activity","type":"exact"},{"name":"mitochondrial intermediate precursor-processing proteinase activity","type":"related"}],"termid":"GO:0004243"}


id: MONDO:0010215
data:
  {"annotated_genes":["SJAG_02556"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88474],"is_not":false,"summary":null,"term":"MONDO:0010215"}]},"cv_name":"mondo","definition":"Any xeroderma pigmentosum in which the cause of the disease is a mutation in the ERCC4 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"xeroderma pigmentosum-Cockayne syndrome complex","termid":"MONDO:0016354"},{"relation_name":"is_a","term_name":"xeroderma pigmentosum","termid":"MONDO:0019600"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02556":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0021190"},{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0021190","MONDO:0005093"],"is_obsolete":false,"name":"xeroderma pigmentosum group F","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:5628","OMIM:278760","SCTID:42530008","NCIT:C3968","UMLS:C0268140","MESH:C562592","Orphanet:276264","DOID:0110848","MEDGEN:120612"],"synonyms":[{"name":"ERCC4 xeroderma pigmentosum","type":"exact"},{"name":"XP group F","type":"exact"},{"name":"XP, group F","type":"exact"},{"name":"XP-F","type":"exact"},{"name":"XP6","type":"exact"},{"name":"XPF","type":"exact"},{"name":"xeroderma pigmentosum 6","type":"related"},{"name":"xeroderma pigmentosum VI","type":"exact"},{"name":"xeroderma pigmentosum caused by mutation in ERCC4","type":"exact"},{"name":"xeroderma pigmentosum group F","type":"exact"},{"name":"xeroderma pigmentosum group type F","type":"exact"},{"name":"xeroderma pigmentosum, complementation group F","type":"related"},{"name":"xeroderma pigmentosum, complementation group type F","type":"exact"},{"name":"xeroderma pigmentosum, group F","type":"exact"},{"name":"xeroderma pigmentosum, type 6","type":"related"},{"name":"xeroderma pigmentosum, type F/Cockayne syndrome","type":"related"}],"termid":"MONDO:0010215","terms_by_termid":{"MONDO:0010215":null},"xrefs":{"Monarch":{"xref_id":"0010215"}}}


id: PBO:0027782
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_protein_threonine_phosphorylation","termid":"PBO:0027782"}


id: MONDO:0017854
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete T-b+ severe combined immunodeficiency (obsolete MONDO:0017854)","termid":"MONDO:0017854","xrefs":{"Monarch":{"xref_id":"0017854"}}}


id: PBO:0048585
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glycoprotein alpha-galactosyltransferase 1 (inactive)","termid":"PBO:0048585"}


id: GO:0036272
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gemcitabine stimulus. Gemcitabine is a 2'-deoxycytidine having geminal fluoro substituents in the 2'-position, and is used as a drug in the treatment of various carcinomas.","definition_xrefs":["Wikipedia:Gemcitabine","GOC:hp"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to nitrogen compound","termid":"GO:1901698"},{"relation_name":"is_a","term_name":"response to oxygen-containing compound","termid":"GO:1901700"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to gemcitabine","synonyms":[{"name":"response to 2',2'-difluorodeoxycytidine","type":"exact"},{"name":"response to 2'-deoxy-2',2'-difluorocytidine","type":"exact"}],"termid":"GO:0036272"}


id: GO:1904373
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a kainic acid stimulus.","definition_xrefs":["GO_REF:0000071","GOC:TermGenie","PMID:17443789"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to amino acid","termid":"GO:0043200"},{"relation_name":"is_a","term_name":"response to nitrogen compound","termid":"GO:1901698"},{"relation_name":"is_a","term_name":"response to oxygen-containing compound","termid":"GO:1901700"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to kainic acid","termid":"GO:1904373"}


id: MONDO:1012475
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"recurrent uveitis, non-human animal","termid":"MONDO:1011997"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"recurrent uveitis, horse","secondary_identifiers":["OMIA:001872-9796"],"termid":"MONDO:1012475","xrefs":{"Monarch":{"xref_id":"1012475"}}}


id: GO:0015943
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"formate metabolic process","termid":"GO:0015942"},{"relation_name":"is_a","term_name":"monocarboxylic acid biosynthetic process","termid":"GO:0072330"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0008150"],"is_obsolete":false,"name":"formate biosynthetic process","synonyms":[{"name":"formate anabolism","type":"exact"},{"name":"formate biosynthesis","type":"exact"},{"name":"formate formation","type":"exact"},{"name":"formate synthesis","type":"exact"},{"name":"formic acid biosynthesis","type":"exact"},{"name":"formic acid biosynthetic process","type":"exact"}],"termid":"GO:0015943"}


id: PBO:0061367
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nucleophosmin 1 pseudogene 27","termid":"PBO:0061367"}


id: PBO:0004581
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Pombe GlycoProtease","termid":"PBO:0004581"}


id: GO:1900836
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of emericellin biosynthetic process.","definition_xrefs":["GOC:TermGenie","GOC:di"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of xanthone-containing compound biosynthetic process","termid":"GO:1900185"},{"relation_name":"is_a","term_name":"positive regulation of secondary metabolite biosynthetic process","termid":"GO:1900378"},{"relation_name":"is_a","term_name":"regulation of emericellin biosynthetic process","termid":"GO:1900834"},{"relation_name":"positively_regulates","term_name":"emericellin biosynthetic process","termid":"GO:1900766"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0019748"},{"rel_name":"positively_regulates","termid":"GO:0019748"},{"rel_name":"positively_regulates","termid":"GO:0044281"},{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0019748","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"positive regulation of emericellin biosynthetic process","termid":"GO:1900836"}


id: MONDO:0016113
data:
  {"annotated_genes":["SJAG_04321","SJAG_01260","SJAG_00754","SJAG_04084","SJAG_04907","SJAG_03328"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88140],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013853"},{"annotations":[88438],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010190"},{"annotations":[88927],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012890"},{"annotations":[88931],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012891"},{"annotations":[88746],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014485"},{"annotations":[87922],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014874"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"spinal muscular atrophy","termid":"MONDO:0001516"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00754":null,"SJAG_01260":null,"SJAG_03328":null,"SJAG_04084":null,"SJAG_04321":null,"SJAG_04907":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"bulbospinal muscular atrophy","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["icd11.foundation:1604214898","UMLS:C0393547","Orphanet:206701","NANDO:1200001","GARD:20365","SCTID:230253001","MEDGEN:95977"],"synonyms":[{"name":"SBMA","type":"exact"},{"name":"bulbospinal muscular atrophy","type":"exact"},{"name":"spinal and bulbal muscular atrophy","type":"exact"},{"name":"spinal-bulbar muscular atrophy","type":"exact"}],"termid":"MONDO:0016113","terms_by_termid":{"MONDO:0010190":null,"MONDO:0012890":null,"MONDO:0012891":null,"MONDO:0013853":null,"MONDO:0014485":null,"MONDO:0014874":null},"xrefs":{"Monarch":{"xref_id":"0016113"}}}


id: MONDO:0028226
data:
  {"annotated_genes":["SJAG_03889"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86843],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014118"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive disease","termid":"MONDO:0006025"},{"relation_name":"is_a","term_name":"severe congenital neutropenia","termid":"MONDO:0018542"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03889":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0005570","MONDO:0005046"],"is_obsolete":false,"name":"autosomal recessive severe congenital neutropenia","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["NCIT:C176624","UMLS:C5447331","Orphanet:439849","MEDGEN:1781858","GARD:21834"],"termid":"MONDO:0028226","terms_by_termid":{"MONDO:0014118":null},"xrefs":{"Monarch":{"xref_id":"0028226"}}}


id: MONDO:0013102
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"excluded_subClassOf","term_name":"skin basal cell carcinoma","termid":"MONDO:0005341"},{"relation_name":"is_a","term_name":"basal cell carcinoma, susceptibility to","termid":"MONDO:0100047"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"basal cell carcinoma, susceptibility to, 3","secondary_identifiers":["MEDGEN:414419","OMIM:613059","UMLS:C2751605"],"synonyms":[{"name":"BCC3","type":"exact"},{"name":"basal cell carcinoma, susceptibility to, 3","type":"exact"}],"termid":"MONDO:0013102","xrefs":{"Monarch":{"xref_id":"0013102"}}}


id: PBO:0063971
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"piwi-interacting RNA cluster 5","termid":"PBO:0063971"}


id: MONDO:1010494
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Ventricular septal defect that occurs in sheep.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ventricular septal defect, non-human animal","termid":"MONDO:1010022"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ventricular septal defect, sheep","secondary_identifiers":["OMIA:001041-9940"],"termid":"MONDO:1010494","xrefs":{"Monarch":{"xref_id":"1010494"}}}


id: GO:0046065
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving dCTP, deoxycytidine triphosphate.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pyrimidine deoxyribonucleoside triphosphate metabolic process","termid":"GO:0009211"},{"relation_name":"is_a","term_name":"pyrimidine deoxyribonucleotide metabolic process","termid":"GO:0009219"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0055086"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0055086"],"is_obsolete":false,"name":"dCTP metabolic process","synonyms":[{"name":"dCTP metabolism","type":"exact"}],"termid":"GO:0046065"}


id: PBO:0053722
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 934","termid":"PBO:0053722"}


id: GO:0043685
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The modification process that results in the conversion of glutamate charged on a tRNA(Gln) to glutaminyl-tRNA.","definition_xrefs":["PMID:9342308","GOC:jsg","PMID:3340166"],"direct_ancestors":[{"relation_name":"is_a","term_name":"charged-tRNA amino acid modification","termid":"GO:0019988"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006399"},{"rel_name":"part_of","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467","GO:0006399"],"is_obsolete":false,"name":"conversion of glutamyl-tRNA to glutaminyl-tRNA","termid":"GO:0043685"}


id: FYPO:0002492
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which DNA 5'-adenosine monophosphate hydrolase activity is absent.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal DNA 5'-adenosine monophosphate hydrolase activity","termid":"FYPO:0002491"},{"relation_name":"is_a","term_name":"abolished nuclease activity","termid":"FYPO:0003164"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000707"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000661","FYPO:0000652","FYPO:0005447","FYPO:0000002","FYPO:0000654","FYPO:0000707"],"is_obsolete":false,"name":"abolished DNA 5'-adenosine monophosphate hydrolase activity","synonyms":[{"name":"DNA 5'-adenosine monophosphate hydrolase activity abolished","type":"exact"}],"termid":"FYPO:0002492"}


id: MONDO:0005376
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A slowly progressive inflammation of the glomeruli characterized by immune complex deposits at the glomerular basement membrane, resulting in a thickened membrane, and nephrotic syndrome.","definition_xrefs":["NCIT:C34645"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glomerulonephritis","termid":"MONDO:0002462"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240"],"is_obsolete":false,"name":"membranous glomerulonephritis","secondary_identifiers":["SCTID:77182004","UMLS:C0017665","MESH:D015433","ICD9:583.1","DOID:10976","NANDO:2200114","MEDGEN:42231","NANDO:1200721","EFO:0004254","ICD9:582.1"],"synonyms":[{"name":"membranous Glomerulonephropathy","type":"exact"},{"name":"membranous nephropathy","type":"exact"}],"termid":"MONDO:0005376","xrefs":{"Monarch":{"xref_id":"0005376"}}}


id: FYPO:0008338
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the addition of one or more uridylyl residues to the 3' ends of non-polyadenylated RNA molecules occurs to a higher extent than normal.","definition_xrefs":["PMID:39333464"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased RNA modification","termid":"FYPO:0000374"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000294"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000294","FYPO:0001985","FYPO:0000002","FYPO:0005447"],"is_obsolete":false,"name":"increased 3' end uridylation of non-polyadenylated RNA","termid":"FYPO:0008338"}


id: GO:0072367
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of lipid transport by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.","definition_xrefs":["GOC:mah","GOC:BHF"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of lipid transport by regulation of transcription from RNA polymerase II promoter (obsolete GO:0072367)","synonyms":[{"name":"regulation of lipid transport by regulation of transcription from an RNA polymerase II promoter","type":"exact"}],"termid":"GO:0072367"}


id: PBO:0068056
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 361","termid":"PBO:0068056"}


id: GO:0044682
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: GTP + H2O = 7,8-dihydroneopterin 2',3'-cyclic phosphate + diphosphate + formate + H+. This activity is part of the biosynthesis of methanopterin in Archaea, and requires Fe2+.","definition_xrefs":["PMID:17497938","GOC:mengo_curators","RHEA:25860"],"direct_ancestors":[{"relation_name":"is_a","term_name":"GTP cyclohydrolase activity","termid":"GO:0003933"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0016810"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016787","GO:0003674","GO:0016810","GO:0003824"],"is_obsolete":false,"name":"GTP cyclohydrolase IV activity","secondary_identifiers":["EC:3.5.4.39"],"synonyms":[{"name":"Fe(2+)-dependent archaeal-specific GTP cyclohydrolase activity","type":"exact"},{"name":"MptA activity","type":"narrow"},{"name":"archaeal-specific GTP cyclohydrolase activity","type":"exact"}],"termid":"GO:0044682"}


id: PBO:0076923
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcription factor CP2 like 1","termid":"PBO:0076923"}


id: FYECO:0000068
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which vaccenic acid was added to the medium or assay buffer in excess compared to standard medium or assay buffers.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"+ fatty acid","termid":"FYECO:0000042"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ vaccenic acid","termid":"FYECO:0000068"}


id: MOD:01674
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-asparagine residue to N4-(N-acetaminohexosyl)-L-asparagine.","definition_xrefs":["Unimod:43#N","OMSSA:182"],"direct_ancestors":[{"relation_name":"is_a","term_name":"N4-glycosyl-L-asparagine","termid":"MOD:00160"},{"relation_name":"is_a","term_name":"N-acetylaminohexosylated residue","termid":"MOD:01673"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00764"}],"interesting_parent_ids":["MOD:00764"],"is_obsolete":false,"name":"N4-(N-acetylamino)hexosyl-L-asparagine","synonyms":[{"name":"(S)-2-amino-4-(2-acetamido-2-deoxy-beta-D-hexopyranosyl)amino-4-oxobutanoic acid","type":"exact"},{"name":"HexNAc","type":"related"},{"name":"HexNAcAsn","type":"exact"},{"name":"N-Acetylhexosamine","type":"related"},{"name":"N4-(2-acetamido-2-deoxy-beta-D-hexopyranosyl)-L-asparagine","type":"exact"},{"name":"N4-(2-acetylamino-2-deoxy-beta-D-hexopyranosyl)-L-asparagine","type":"exact"},{"name":"N4-(N-acetylhexosaminyl)asparagine","type":"exact"},{"name":"N4-asparagine-beta-N-acetylhexosaminide","type":"exact"},{"name":"N4-glycosyl-L-asparagine","type":"exact"},{"name":"N4-glycosylasparagine","type":"exact"},{"name":"N4HexNAcAsn","type":"exact"},{"name":"hexNAcN","type":"exact"}],"termid":"MOD:01674"}


id: PBO:0084966
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"N-acetyltransferase; confers resistance to the sphingolipid biosynthesis inhibitor myriocin (ISP-1) by converting it into N-acetyl-myriocin, co-operates with Ypk1p in mediating resistance to myriocin","termid":"PBO:0084966"}


id: PBO:0041495
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 12 open reading frame 54","termid":"PBO:0041495"}


id: PBO:0071088
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L21 pseudogene 90","termid":"PBO:0071088"}


id: PBO:0082021
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zyg-11 family member A, cell cycle regulator pseudogene 1","termid":"PBO:0082021"}


id: FYPO:0006831
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which primary cell septum biogenesis begins later than normal.","definition_xrefs":["GO:0031671","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal primary cell septum biogenesis","termid":"FYPO:0003890"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000032"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000032","FYPO:0001985","FYPO:0000002","FYPO:0000631","FYPO:0005447"],"is_obsolete":false,"name":"delayed onset of primary cell septum biogenesis","synonyms":[{"name":"delayed onset of primary cell septum biogenesis during mitotic cell cycle","type":"related"},{"name":"delayed onset of primary cell septum biogenesis during vegetative growth","type":"exact"},{"name":"delayed onset of primary cell septum formation","type":"exact"},{"name":"delayed onset of primary septum biogenesis","type":"exact"},{"name":"delayed onset of primary septum synthesis","type":"related"},{"name":"delayed primary cell septum biogenesis","type":"exact"}],"termid":"FYPO:0006831"}


id: PBO:0004571
data:
  {"annotation_feature_type":"gene","cv_name":"misc","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"localizes to DNA damage foci","termid":"PBO:0004571"}


id: PBO:0047622
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fidgetin like 1","termid":"PBO:0047622"}


id: GO:0106300
data:
  {"annotated_genes":["SJAG_00406","SJAG_02223"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[100219,108046],"is_not":false,"summary":null,"term":"GO:0106300"}]},"cv_name":"biological_process","definition":"The removal of covalent cross-link between DNA and a protein.","definition_xrefs":["PMID:31921408"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA repair","termid":"GO:0006281"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00406":null,"SJAG_02223":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006281"},{"rel_name":"is_a","termid":"GO:0006259"}],"interesting_parent_ids":["GO:0008150","GO:0006281","GO:0006259"],"is_obsolete":false,"name":"protein-DNA covalent cross-linking repair","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"resolution of protein-DNA covalent cross-linking","type":"exact"}],"termid":"GO:0106300","terms_by_termid":{"GO:0106300":null}}


id: PBO:0082977
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cytoplasmic thioredoxin reductase; key regulatory enzyme that determines the redox state of the thioredoxin system, which acts as a disulfide reductase system and protects cells against both oxidative and reductive stress; protein abundance increases in response to DNA replication stress; TRR1 has a paralog, TRR2, that arose from the whole genome duplication","termid":"PBO:0082977"}


id: PBO:0047457
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ficolin 1","termid":"PBO:0047457"}


id: PATO:0001386
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"An aneuploidy quality inhering in a bearer by virtue of the bearer's containing only one chromosome from a pair in a cell's nucleus.","definition_xrefs":["Wikipedia:http://en.wikipedia.org/wiki/Monosomy"],"direct_ancestors":[{"relation_name":"is_a","term_name":"aneuploid","termid":"PATO:0001385"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"monosomy","termid":"PATO:0001386"}


id: MOD:00994
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"modification from DeltaMass","definition_xrefs":["DeltaMass:0"],"direct_ancestors":[{"relation_name":"is_a","term_name":"3'-bromo-L-tyrosine","termid":"MOD:01025"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"(79)Br labeled 3'-bromotyrosine","termid":"MOD:00994"}


id: MONDO:1010535
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Megacolon that occurs in domestic cat.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"megacolon, non-human animal","termid":"MONDO:1010039"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"megacolon, domestic cat","secondary_identifiers":["OMIA:000629-9685"],"termid":"MONDO:1010535","xrefs":{"Monarch":{"xref_id":"1010535"}}}


id: GO:0045544
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2 2-oxoglutarate + gibberellin A12 (GA12) + H+ + 3 O2 = 3 CO2 + gibberellin A9 (GA9) + 2 H2O + 2 succinate. This reaction results in the oxidation of C-20 gibberellins to form the corresponding C-19 lactones, via a three-step oxidation at C-20 of the GA skeleton. Also converts GA53 to GA20. GA25 is also formed as a minor product.","definition_xrefs":["PMID:7604047","PMID:32652020"],"direct_ancestors":[{"relation_name":"is_a","term_name":"2-oxoglutarate-dependent dioxygenase activity","termid":"GO:0016706"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"gibberellin 20-oxidase activity","termid":"GO:0045544"}


id: SO:0000175
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A conserved region about 10-bp upstream of the start point of bacterial transcription units which may be involved in binding RNA polymerase; consensus=TAtAaT. This region is associated with sigma factor 70.","direct_ancestors":[{"relation_name":"is_a","term_name":"DNA_motif","termid":"SO:0000713"},{"relation_name":"part_of","term_name":"bacterial_RNApol_promoter_sigma_70_element","termid":"SO:0001671"},{"relation_name":"part_of","term_name":"bacterial_RNApol_promoter_sigma_ecf_element","termid":"SO:0001913"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"minus_10_signal","secondary_identifiers":["http://en.wikipedia.org/wiki/Pribnow_box"],"synonyms":[{"name":"-10 signal","type":"exact"},{"name":"INSDC_feature:regulatory","type":"broad"},{"name":"INSDC_qualifier:minus_10_signal","type":"exact"},{"name":"Pribnow Schaller box","type":"exact"},{"name":"Pribnow box","type":"exact"},{"name":"Pribnow-Schaller box","type":"exact"},{"name":"minus 10 signal","type":"exact"}],"termid":"SO:0000175"}


id: PBO:0065754
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glycogen phosphorylase L","termid":"PBO:0065754"}


id: GO:0007060
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a male.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"meiotic chromosome segregation","termid":"GO:0045132"},{"relation_name":"part_of","term_name":"male meiotic nuclear division","termid":"GO:0007140"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0007049"},{"rel_name":"part_of","termid":"GO:0140013"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0007049","GO:0140013"],"is_obsolete":false,"name":"male meiosis chromosome segregation","termid":"GO:0007060"}


id: PBO:0083062
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dihydrolipoyl transsuccinylase; component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes the oxidative decarboxylation of alpha-ketoglutarate to succinyl-CoA in the TCA cycle; phosphorylated","termid":"PBO:0083062"}


id: GO:0005771
data:
  {"annotated_genes":["SJAG_04489","SJAG_04643","SJAG_00181","SJAG_03892","SJAG_05210","SJAG_03976","SJAG_04047","SJAG_02100","SJAG_03783","SJAG_00900","SJAG_00416","SJAG_05207","SJAG_01242","SJAG_01088"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[71889,72459,72785,77572,77755,77997,81027,107704,115298,116445,121184],"is_not":false,"summary":null,"term":"GO:0005771"},{"annotations":[63062,121186,60859],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0032585"}]},"cv_name":"cellular_component","definition":"A type of endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.","definition_xrefs":["PMID:16533950","PMID:11566881"],"direct_ancestors":[{"relation_name":"is_a","term_name":"late endosome","termid":"GO:0005770"}],"gene_count":14,"genes_by_uniquename":{"SJAG_00181":null,"SJAG_00416":null,"SJAG_00900":null,"SJAG_01088":null,"SJAG_01242":null,"SJAG_02100":null,"SJAG_03783":null,"SJAG_03892":null,"SJAG_03976":null,"SJAG_04047":null,"SJAG_04489":null,"SJAG_04643":null,"SJAG_05207":null,"SJAG_05210":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0031410"},{"rel_name":"is_a","termid":"GO:0005768"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0031410","GO:0005737","GO:0005768"],"is_obsolete":false,"name":"multivesicular body","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000044":null,"GO_REF:0000104":null,"GO_REF:0000107":null,"PMID:32109380":null},"secondary_identifiers":["NIF_Subcellular:sao2045955158"],"synonyms":[{"name":"MVB","type":"exact"},{"name":"MVE","type":"exact"},{"name":"multivesicular endosome","type":"exact"}],"termid":"GO:0005771","terms_by_termid":{"GO:0005771":null,"GO:0032585":null}}


id: PBO:0046811
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"F11 receptor","termid":"PBO:0046811"}


id: GO:0052183
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process in which a host organism destabilizes a cellular component of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"gene_count":0,"genotype_count":0,"name":"obsolete disruption of symbiont cellular component (obsolete GO:0052183)","synonyms":[{"name":"degradation of symbiont cellular component by organism","type":"related"},{"name":"disassembly by host of symbiont cellular component","type":"narrow"},{"name":"disruption by host of symbiont cellular component","type":"related"},{"name":"disruption by host of symbiont structure","type":"exact"},{"name":"modification by host of symbiont cellular component","type":"exact"},{"name":"modification by host of symbiont structure","type":"broad"},{"name":"perturbation of symbiont cellular component","type":"exact"}],"termid":"GO:0052183"}


id: PBO:0028820
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_replication_fork_reversal","termid":"PBO:0028820"}


id: MONDO:0004635
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A primary or metastatic malignant neoplasm that affects the postcricoid region.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hypopharynx cancer","termid":"MONDO:0005806"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0004335"],"is_obsolete":false,"name":"postcricoid region cancer","secondary_identifiers":["MEDGEN:141673","NCIT:C9323","ICD9:148.0","SCTID:363400004","DOID:8660","UMLS:C0496769"],"synonyms":[{"name":"malignant neoplasm of postcricoid area","type":"exact"},{"name":"malignant neoplasm of the postcricoid area","type":"exact"},{"name":"malignant postcricoid neoplasm","type":"exact"},{"name":"malignant postcricoid tumor","type":"exact"},{"name":"malignant postcricoid tumour","type":"exact"},{"name":"malignant tumor of pharyngoesophageal junction","type":"exact"},{"name":"malignant tumor of postcricoid area","type":"exact"},{"name":"malignant tumor of the postcricoid area","type":"exact"},{"name":"malignant tumour of pharyngoesophageal junction","type":"exact"},{"name":"malignant tumour of postcricoid area","type":"exact"},{"name":"malignant tumour of the postcricoid area","type":"exact"}],"termid":"MONDO:0004635","xrefs":{"Monarch":{"xref_id":"0004635"}}}


id: PBO:0090022
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"unknown protein, may bind replication origins Abp2","termid":"PBO:0090022"}


id: PBO:0041806
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"caspase recruitment domain family member 17, pseudogene","termid":"PBO:0041806"}


id: GO:0005500
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a juvenile hormone, a sesquiterpenoid derivative that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.","definition_xrefs":["GOC:jl","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"isoprenoid binding","termid":"GO:0019840"},{"relation_name":"is_a","term_name":"hormone binding","termid":"GO:0042562"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0008289"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0003674","GO:0008289","GO:0005488"],"is_obsolete":false,"name":"juvenile hormone binding","termid":"GO:0005500"}


id: MONDO:0970995
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"inherited primary ovarian failure","termid":"MONDO:0019852"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005047"}],"interesting_parent_ids":["MONDO:0005047"],"is_obsolete":false,"name":"premature ovarian failure 24","secondary_identifiers":["UMLS:C5935624","MEDGEN:1858807","OMIM:620840"],"termid":"MONDO:0970995","xrefs":{"Monarch":{"xref_id":"0970995"}}}


id: GO:0033137
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-serine.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of protein phosphorylation","termid":"GO:0001933"},{"relation_name":"is_a","term_name":"regulation of peptidyl-serine phosphorylation","termid":"GO:0033135"},{"relation_name":"negatively_regulates","term_name":"peptidyl-serine phosphorylation","termid":"GO:0018105"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of peptidyl-serine phosphorylation","termid":"GO:0033137"}


id: PBO:0041065
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"brain protein I3","termid":"PBO:0041065"}


id: MONDO:0957460
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"intestinal perforation","termid":"MONDO:0006807"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"spontaneous intestinal perforation","secondary_identifiers":["Orphanet:645793","icd11.foundation:1355081169","UMLS:C3897004","MEDGEN:856598"],"termid":"MONDO:0957460","xrefs":{"Monarch":{"xref_id":"0957460"}}}


id: PBO:0047597
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FHAD1 antisense RNA 1","termid":"PBO:0047597"}


id: PBO:0090043
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ER oxidoreductase Pbr1, implicated in lipid metabolism","termid":"PBO:0090043"}


id: MONDO:0003227
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Impaired ability to recognize other human faces in the absence of a vision disorder. It may be a congenital disorder or the result of brain injury.","definition_xrefs":["NCIT:C85031"],"direct_ancestors":[{"relation_name":"is_a","term_name":"agnosia","termid":"MONDO:0005638"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"prosopagnosia","secondary_identifiers":["DOID:4970","icd11.foundation:858616900","UMLS:C0234512","MEDGEN:65884","HP:0010528","MESH:D020238"],"synonyms":[{"name":"face blindness","type":"exact"},{"name":"prosopagnosia","type":"exact"},{"name":"prosopagnosia (disease)","type":"exact"}],"termid":"MONDO:0003227","xrefs":{"Monarch":{"xref_id":"0003227"}}}


id: PBO:0089331
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"V-type ATPase V0 subunit d","termid":"PBO:0089331"}


id: PBO:0087488
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of COMPASS (Set1C) complex; COMPASS methylates Lys4 of histone H3 and functions in silencing at telomeres; has a C-terminal Sdc1 Dpy-30 Interaction (SDI) domain that mediates binding to Sdc1p; similar to trithorax-group protein ASH2L","termid":"PBO:0087488"}


id: GO:0071510
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of conjugation with cellular fusion.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete activation of MAPKKK activity involved in conjugation with cellular fusion (obsolete GO:0071510)","synonyms":[{"name":"activation of MAP kinase kinase kinase activity during conjugation with cellular fusion","type":"exact"},{"name":"activation of MAPKKK activity involved in mating response","type":"related"},{"name":"conjugation with cellular fusion, activation of MAP kinase kinase kinase activity","type":"exact"},{"name":"conjugation with cellular fusion, activation of MAPKKK activity","type":"exact"}],"termid":"GO:0071510"}


id: PBO:0063156
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"paired box 2","termid":"PBO:0063156"}


id: GO:2000927
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of cellodextrin catabolic process.","definition_xrefs":["GOC:mengo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of carbohydrate catabolic process","termid":"GO:0043470"},{"relation_name":"is_a","term_name":"regulation of cellodextrin metabolic process","termid":"GO:2000924"},{"relation_name":"regulates","term_name":"cellodextrin catabolic process","termid":"GO:2000890"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0005975","GO:0008150"],"is_obsolete":false,"name":"regulation of cellodextrin catabolic process","synonyms":[{"name":"regulation of cellodextrin catabolism","type":"exact"}],"termid":"GO:2000927"}


id: SO:0001414
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"The point within a chromosome where a insertion begins or ends.","definition_xrefs":["SO:cb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chromosome_breakpoint","termid":"SO:0001021"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"insertion_breakpoint","synonyms":[{"name":"insertion breakpoint","type":"exact"}],"termid":"SO:0001414"}


id: GO:1901144
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways resulting in the formation of insulin.","definition_xrefs":["GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete insulin biosynthetic process (obsolete GO:1901144)","synonyms":[{"name":"insulin anabolism","type":"exact"},{"name":"insulin biosynthesis","type":"exact"},{"name":"insulin biosynthetic process","type":"exact"},{"name":"insulin formation","type":"exact"},{"name":"insulin synthesis","type":"exact"}],"termid":"GO:1901144"}


id: PBO:0082754
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of the septin ring, required for cytokinesis; septins are GTP-binding proteins that assemble into rod-like hetero-oligomers that can associate to form filaments; septin rings at the mother-bud neck act as scaffolds for recruiting cell division factors and as barriers to prevent diffusion of specific proteins between mother and daughter cells; N-terminus interacts with phosphatidylinositol-4,5-bisphosphate; protein abundance increases under DNA damage stress","termid":"PBO:0082754"}


id: PBO:0062925
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"purinergic receptor P2Y12","termid":"PBO:0062925"}


id: MOD:00557
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"modification from Unimod Other","definition_xrefs":["Unimod:206","PubMed:10825247","PubMed:15541752"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Unimod","termid":"MOD:00003"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acrolein addition +56","synonyms":[{"name":"Acrolein addition +56","type":"related"},{"name":"Delta:H(4)C(3)O(1)","type":"related"}],"termid":"MOD:00557"}


id: PR:O42851
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC23A1.14c gene.","definition_xrefs":["PRO:DNx","UniProtKB:O42851"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized trans-sulfuration enzyme C23A1.14c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC23A1.14c","synonyms":[{"name":"Spom972h-SPAC23A1.14c","type":"exact"}],"termid":"PR:O42851"}


id: FYECO:0000325
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which ethylene glycol was added to the medium or assay buffer in excess compared to standard medium or assay buffers.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping excess","termid":"FYECO:0000109"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ ethylene glycol","termid":"FYECO:0000325"}


id: PBO:0085738
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein involved in transcription initiation; acts at TATA-containing promoters; associates with the basal transcription factor TFIID; contains two bromodomains; corresponds to the C-terminal region of mammalian TAF1; redundant with Bdf1p; protein abundance increases in response to DNA replication stress; BDF2 has a paralog, BDF1, that arose from the whole genome duplication","termid":"PBO:0085738"}


id: MONDO:0016136
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete cerebellar ataxia with peripheral neuropathy (obsolete MONDO:0016136)","secondary_identifiers":["Orphanet:207028"],"termid":"MONDO:0016136","xrefs":{"Monarch":{"xref_id":"0016136"}}}


id: GO:0048387
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of retinoic acid receptor signaling pathway activity.","definition_xrefs":["GOC:dgh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of retinoic acid receptor signaling pathway","termid":"GO:0048385"},{"relation_name":"is_a","term_name":"negative regulation of intracellular signal transduction","termid":"GO:1902532"},{"relation_name":"negatively_regulates","term_name":"retinoic acid receptor signaling pathway","termid":"GO:0048384"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"negative regulation of retinoic acid receptor signaling pathway","synonyms":[{"name":"down regulation of retinoic acid receptor signaling pathway","type":"exact"},{"name":"down-regulation of retinoic acid receptor signaling pathway","type":"exact"},{"name":"downregulation of retinoic acid receptor signaling pathway","type":"exact"},{"name":"inhibition of retinoic acid receptor signaling pathway","type":"narrow"},{"name":"negative regulation of RAR signaling pathway","type":"exact"},{"name":"negative regulation of RAR signalling pathway","type":"exact"},{"name":"negative regulation of retinoic acid receptor signalling pathway","type":"exact"}],"termid":"GO:0048387"}


id: MONDO:0016778
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Iatrogenic botulism is the most recent man-made form of botulism, a rare acquired neuromuscular junction disease with descending flaccid paralysis caused by botulinum neurotoxins (BoNTs), and it may occur as an adverse event after therapeutic or cosmetic use.","definition_xrefs":["Orphanet:254509"],"direct_ancestors":[{"relation_name":"is_a","term_name":"botulism","termid":"MONDO:0005498"},{"relation_name":"is_a","term_name":"nosocomial infection","termid":"MONDO:0043544"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"iatrogenic botulism","secondary_identifiers":["icd11.foundation:230654666","MEDGEN:926454","NCIT:C128345","GARD:20747","UMLS:C4288922"],"synonyms":[{"name":"accidental botulism","type":"exact"},{"name":"inadvertent botulism","type":"exact"}],"termid":"MONDO:0016778","xrefs":{"Monarch":{"xref_id":"0016778"}}}


id: FYPO:0003485
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the biosynthesis of DNA does not occur.","definition_xrefs":["GO:0071897","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA metabolism phenotype during vegetative growth","termid":"FYPO:0001346"},{"relation_name":"is_a","term_name":"abolished cellular process","termid":"FYPO:0005449"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000293"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000293","FYPO:0005447","FYPO:0000002","FYPO:0001985","FYPO:0001320"],"is_obsolete":false,"name":"abolished DNA synthesis","synonyms":[{"name":"abolished DNA biosynthesis","type":"exact"},{"name":"abolished DNA biosynthetic process","type":"exact"},{"name":"abolished DNA synthesis during mitotic cell cycle","type":"related"},{"name":"abolished DNA synthesis during vegetative growth","type":"exact"}],"termid":"FYPO:0003485"}


id: PBO:0051681
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"inhibin subunit beta C","termid":"PBO:0051681"}


id: PBO:0087048
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ribosomal 60S subunit protein L22A; required for translation of long 5' UTR of IME1 mRNA and meiotic entry; required for the oxidative stress response, pseudohyphal and invasive growth; homologous to mammalian ribosomal protein L22, no bacterial homolog; RPL22A has a paralog, RPL22B, that arose from the whole genome duplication","termid":"PBO:0087048"}


id: PBO:0090740
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"metallopeptidase Oma1","termid":"PBO:0090740"}


id: PR:Q9URZ1
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein-L-isoaspartate(D-aspartate) O-methyltransferase that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO02279","PANTHER:PTHR11579:SF0","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein-L-isoaspartate O-methyltransferase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC869.08","secondary_identifiers":["UniProtKB:Q9URZ1"],"synonyms":[{"name":"L-isoaspartyl protein carboxyl methyltransferase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"PIMT (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-PCMT1","type":"exact"},{"name":"protein L-isoaspartyl methyltransferase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"protein-beta-aspartate methyltransferase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9URZ1"}


id: PBO:0062499
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 8 subfamily D member 4","termid":"PBO:0062499"}


id: GO:0055050
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The aggregation, arrangement and bonding together of a set of components to form the astral spindle in male meiotic cells.","definition_xrefs":["GOC:tb"],"gene_count":0,"genotype_count":0,"name":"obsolete astral spindle assembly involved in male meiosis (obsolete GO:0055050)","termid":"GO:0055050"}


id: GO:0050108
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (2S,4R)-bornyl diphosphate + H2O = (1R,2S,4R)-borneol + diphosphate.","definition_xrefs":["PMID:42357","EC:3.1.7.3"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphatase activity","termid":"GO:0016791"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016787","GO:0016788"],"is_obsolete":false,"name":"monoterpenyl-diphosphatase activity","secondary_identifiers":["RHEA:81371","MetaCyc:MONOTERPENYL-PYROPHOSPHATASE-RXN"],"synonyms":[{"name":"bornyl diphosphate hydrolase activity","type":"related"},{"name":"bornyl pyrophosphate hydrolase activity","type":"related"},{"name":"monoterpenyl-diphosphate diphosphohydrolase activity","type":"related"},{"name":"monoterpenyl-pyrophosphatase activity","type":"exact"}],"termid":"GO:0050108"}


id: PBO:0055744
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"LMX1B divergent transcript","termid":"PBO:0055744"}


id: MOD:01395
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively results from forming an adduct between an isoleucine residue, a threonine residue and the quinaldate compound 2-carboxy-4-(1-hydroxyethyl)--7,8-dihydroquinolin-8-ol.","definition_xrefs":["PubMed:11320328","RESID:AA0472"],"direct_ancestors":[{"relation_name":"is_a","term_name":"quinaldate modified residue","termid":"MOD:01424"},{"relation_name":"is_a","term_name":"crosslinked L-isoleucine residue","termid":"MOD:02049"},{"relation_name":"is_a","term_name":"crosslinked L-threonine residue","termid":"MOD:02056"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"4-(1-hydroxyethyl)-7-isoleucino-2-(threonin-O3-ylcarbonyl)-7,8-dihydroquinolin-8-ol","synonyms":[{"name":"(7R,8S)-7-[(1S,2S)-1-carboxy-2-methylbutyl]amino-2-([(1S,2R)-1-amino-1-carboxypropan-2-yl]oxy)carbonyl-8-hydroxy-4-[(1S)-1-hydroxyethyl]-7,8-dihydroquinoline","type":"exact"},{"name":"4-(1-hydroxyethyl)-7-isoleucino-2-(threonin-O3-ylcarbonyl)-7,8-dihydroquinolin-8-ol","type":"exact"},{"name":"BINDING 4-(1-hydroxyethyl)-7,8-dihydroquinolin-8-ol (covalent; via 2 links)","type":"exact"}],"termid":"MOD:01395"}


id: PBO:0047698
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FLYWCH-type zinc finger 1 pseudogene 1","termid":"PBO:0047698"}


id: GO:0030003
data:
  {"annotated_genes":["SJAG_01400","SJAG_04867","SJAG_01129","SJAG_04698","SJAG_04757","SJAG_02883","SJAG_01004","SJAG_03879","SJAG_02716","SJAG_02023","SJAG_03962","SJAG_01541","SJAG_04258","SJAG_00516","SJAG_01913","SJAG_01397","SJAG_04584","SJAG_00532","SJAG_04185","SJAG_04028","SJAG_00605","SJAG_01435","SJAG_04403","SJAG_03516","SJAG_04675","SJAG_01669","SJAG_01817","SJAG_04167","SJAG_04955","SJAG_00802","SJAG_03631","SJAG_04032","SJAG_03866","SJAG_01353","SJAG_02240","SJAG_01078","SJAG_03528","SJAG_02019","SJAG_00916","SJAG_05294","SJAG_00136","SJAG_04607","SJAG_01007","SJAG_01694","SJAG_00212","SJAG_04616","SJAG_04031","SJAG_02532","SJAG_04096","SJAG_02080","SJAG_04677","SJAG_02735","SJAG_02968","SJAG_02399","SJAG_02847","SJAG_03667","SJAG_03850","SJAG_04760","SJAG_03862","SJAG_02457","SJAG_00222","SJAG_01990","SJAG_00328","SJAG_00792","SJAG_02578","SJAG_00923","SJAG_00822","SJAG_00301","SJAG_02474","SJAG_04892","SJAG_03793","SJAG_02470","SJAG_00668","SJAG_02834","SJAG_04743","SJAG_01803"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[59554,102410,95995,114786,79495],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0010106"},{"annotations":[72546],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0032468"},{"annotations":[81972,82019,101837,71874,75420,76931,74179,120604,80195,115353,100022,73196,75354,75274,72842,110769],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006874"},{"annotations":[76810,102082,79821,109812,95017],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006878"},{"annotations":[76040,79962,106193,94185,59207,95941,76811,79822,72923,77527],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006879"},{"annotations":[76253,72058],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010961"},{"annotations":[77525,75456],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0030026"},{"annotations":[97339,79880,73982,72424,101838],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0030007"},{"annotations":[106248,96619,116342,77678,80090,105507,76507,74561,75944,102083,78968,106108],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006882"},{"annotations":[105719],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033212"},{"annotations":[115204],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0098711"},{"annotations":[94330,79493],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033215"},{"annotations":[102436],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0030641"},{"annotations":[73158,67940,72556,74974,79698],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051453"},{"annotations":[62566,62894,71068],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033214"},{"annotations":[105843,97552,97732,89894,75844,72651,101937,103569,81837,74541,80298,74804],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0007035"}]},"cv_name":"biological_process","definition":"A homeostatic process involved in the maintenance of a steady state level of monoatomic cations within a cell. 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id: GO:0000481
data:
  {"annotated_genes":["SJAG_04433"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[80164],"is_not":false,"summary":null,"term":"GO:0000481"}]},"cv_name":"biological_process","definition":"Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule.","definition_xrefs":["GOC:curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"rRNA processing","termid":"GO:0006364"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04433":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0042254"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"part_of","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0044085","GO:0042254","GO:0008150","GO:0010467"],"is_obsolete":false,"name":"maturation of 5S rRNA","references_by_uniquename":{"GO_REF:0000033":null},"termid":"GO:0000481","terms_by_termid":{"GO:0000481":null}}


id: GO:1900850
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of pseurotin A biosynthetic process.","definition_xrefs":["GOC:TermGenie","GOC:di"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of biosynthetic process","termid":"GO:0009890"},{"relation_name":"is_a","term_name":"negative regulation of amide metabolic process","termid":"GO:0034249"},{"relation_name":"is_a","term_name":"negative regulation of small molecule metabolic process","termid":"GO:0062014"},{"relation_name":"is_a","term_name":"regulation of pseurotin A biosynthetic process","termid":"GO:1900849"},{"relation_name":"negatively_regulates","term_name":"pseurotin A biosynthetic process","termid":"GO:1900790"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"negatively_regulates","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0044281"],"is_obsolete":false,"name":"negative regulation of pseurotin A biosynthetic process","synonyms":[{"name":"down regulation of pseurotin A biosynthetic process","type":"exact"},{"name":"down-regulation of pseurotin A biosynthetic process","type":"exact"},{"name":"downregulation of pseurotin A biosynthetic process","type":"exact"}],"termid":"GO:1900850"}


id: GO:0018565
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 1,2-dihydroxydibenzothiophene + O2 = cis-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate.","definition_xrefs":["UM-BBD_reactionID:r0162"],"gene_count":0,"genotype_count":0,"name":"obsolete dihydroxydibenzothiophene dioxygenase activity (obsolete GO:0018565)","termid":"GO:0018565"}


id: GO:0035635
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a bacterium enters a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:bf","PMID:21187937"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont entry into host","termid":"GO:0044409"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"entry of bacterium into host cell","synonyms":[{"name":"bacterial entry into host cell","type":"exact"},{"name":"invasion of bacteria into host cell","type":"exact"}],"termid":"GO:0035635"}


id: PBO:0059635
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-CO1 pseudogene 1","termid":"PBO:0059635"}


id: MONDO:0011601
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Neonatal intrahepatic cholestasis due to citrin deficiency is a mild subtype of citrin deficiency characterized clinically by low birth weight, failure to thrive, transient intrahepatic cholestasis, multiple aminoacidemia, galactosemia, hypoproteinemia, hepatomegaly, decreased coagulation factors, hemolytic anemia, variable but mostly mild liver dysfunction, and hypoglycemia.","definition_xrefs":["Orphanet:247598"],"direct_ancestors":[{"relation_name":"is_a","term_name":"citrin deficiency","termid":"MONDO:0016602"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004736"}],"interesting_parent_ids":["MONDO:0004736","MONDO:0005066"],"is_obsolete":false,"name":"neonatal intrahepatic cholestasis due to citrin deficiency","secondary_identifiers":["UMLS:C1853942","OMIM:605814","NANDO:1200979","SCTID:717155003","MESH:C536398","DOID:0070341","GARD:10214","MEDGEN:340091"],"synonyms":[{"name":"NICCD","type":"exact"},{"name":"cholestasis, neonatal intrahepatic, caused by citrin deficiency","type":"related"},{"name":"citrullinemia, type II, neonatal-onset","type":"related"},{"name":"citrullinemia, type II, neonatal-onset, with or without failure to thrive and dyslipidaemia","type":"related"},{"name":"citrullinemia, type II, neonatal-onset, with or without failure to thrive and dyslipidemia","type":"related"},{"name":"neonatal intrahepatic cholestasis caused by citrin deficiency","type":"exact"},{"name":"neonatal intrahepatic cholestasis due to citrin deficiency","type":"exact"},{"name":"neonatal-onset citrullinemia type 2","type":"related"},{"name":"neonatal-onset citrullinemia type II","type":"related"}],"termid":"MONDO:0011601","xrefs":{"Monarch":{"xref_id":"0011601"}}}


id: MONDO:0012501
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete mutagen sensitivity (obsolete MONDO:0012501)","secondary_identifiers":["OMIM:610452"],"synonyms":[{"name":"mutagen sensitivity","type":"exact"}],"termid":"MONDO:0012501","xrefs":{"Monarch":{"xref_id":"0012501"}}}


id: MONDO:0020665
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"cancer","termid":"MONDO:0004992"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"high grade malignant neoplasm","secondary_identifiers":["UMLS:C1334017","NCIT:C36046","MEDGEN:234350"],"synonyms":[{"name":"high grade malignant neoplasm","type":"exact"}],"termid":"MONDO:0020665","xrefs":{"Monarch":{"xref_id":"0020665"}}}


id: PBO:0063792
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PHD finger protein 20 like 1","termid":"PBO:0063792"}


id: GO:0016157
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: an NDP-alpha-D-glucose + D-fructose = a ribonucleoside 5'-diphosphate + H+ + sucrose. The phosphate acceptor can be UDP or ADP.","definition_xrefs":["RHEA:16241"],"direct_ancestors":[{"relation_name":"is_a","term_name":"UDP-glucosyltransferase activity","termid":"GO:0035251"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016757"}],"interesting_parent_ids":["GO:0003674","GO:0016740","GO:0003824","GO:0016757"],"is_obsolete":false,"name":"sucrose synthase activity","secondary_identifiers":["EC:2.4.1.13","MetaCyc:SUCROSE-SYNTHASE-RXN"],"synonyms":[{"name":"NDP-glucose:D-fructose 2-alpha-D-glucosyltransferase activity","type":"related"},{"name":"UDP-glucose-fructose glucosyltransferase activity","type":"related"},{"name":"UDPglucose-fructose glucosyltransferase activity","type":"related"},{"name":"sucrose synthetase activity","type":"related"},{"name":"sucrose-UDP glucosyltransferase activity","type":"related"},{"name":"sucrose-uridine diphosphate glucosyltransferase activity","type":"related"},{"name":"uridine diphosphoglucose-fructose glucosyltransferase activity","type":"related"}],"termid":"GO:0016157"}


id: GO:0090540
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as it occurs in certain types of bacteria, mainly Acetobacter, Sarcina ventriculi and Agrobacteria.","definition_xrefs":["GOC:yaf","PMID:24097954"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellulose biosynthetic process","termid":"GO:0030244"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0005975","GO:0008150"],"is_obsolete":false,"name":"bacterial cellulose biosynthetic process","synonyms":[{"name":"bacterial cellulose biosynthesis","type":"exact"}],"termid":"GO:0090540"}


id: MONDO:0009364
data:
  {"annotated_genes":["SJAG_04053","SJAG_01491","SJAG_04316"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87676,87677,87678],"is_not":false,"summary":null,"term":"MONDO:0009364"}]},"cv_name":"mondo","definition":"An autosomal recessive muscular dystrophy caused by mutations in the POMT1 gene, encoding protein O-mannosyl-transferase 1. It is associated with characteristic brain and eye malformations, profound mental retardation, and early death.","definition_xrefs":["NCIT:C128118"],"direct_ancestors":[{"relation_name":"is_a","term_name":"muscular dystrophy-dystroglycanopathy, type A","termid":"MONDO:0000171"},{"relation_name":"is_a","term_name":"muscle-eye-brain disease","termid":"MONDO:0018939"},{"relation_name":"is_a","term_name":"myopathy caused by variation in POMT1","termid":"MONDO:0700070"}],"gene_count":3,"genes_by_uniquename":{"SJAG_01491":null,"SJAG_04053":null,"SJAG_04316":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0024322"},{"rel_name":"is_a","termid":"MONDO:0005336"},{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320","MONDO:0005066","MONDO:0024322","MONDO:0005336"],"is_obsolete":false,"name":"muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A1","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C4284790","DOID:0111237","OMIM:236670","MEDGEN:924974"],"synonyms":[{"name":"MDDGA1","type":"related"},{"name":"Walker-Warburg syndrome or muscle-eye-brain disease, Pomt1-related","type":"related"},{"name":"cerebroocular dysplasia-muscular dystrophy syndrome","type":"related"},{"name":"cod-MD syndrome","type":"related"},{"name":"hard syndrome","type":"related"},{"name":"hydrocephalus, agyria, and retinal dysplasia","type":"related"},{"name":"muscle-eye-brain-POMT1 related","type":"exact"},{"name":"muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies) type A, 1","type":"exact"},{"name":"muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A, 1","type":"related"}],"termid":"MONDO:0009364","terms_by_termid":{"MONDO:0009364":null},"xrefs":{"Monarch":{"xref_id":"0009364"}}}


id: PBO:0063404
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosducin like 3","termid":"PBO:0063404"}


id: PBO:0055082
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2500","termid":"PBO:0055082"}


id: PBO:0029279
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_protein_localization_to_mitotic_spindle_pole_body_during_telophase","termid":"PBO:0029279"}


id: MOD:01323
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"modification from Unimod Other -","definition_xrefs":["Unimod:256#H"],"direct_ancestors":[{"relation_name":"is_a","term_name":"propionaldehyde +40","termid":"MOD:00579"},{"relation_name":"is_a","term_name":"modified L-histidine residue","termid":"MOD:00909"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"propionaldehyde +40 - site H","synonyms":[{"name":"Delta:H(4)C(3)","type":"related"},{"name":"Propionaldehyde +40","type":"related"}],"termid":"MOD:01323"}


id: PBO:0079093
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Tyr (anticodon GTA) 6-1","termid":"PBO:0079093"}


id: GO:1990473
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a ciliary targeting sequence, a specific peptide sequence that acts as a signal to localize a membrane protein to the ciliary membrane.","definition_xrefs":["PMID:18256283","PMID:20603001","GOC:krc","PMID:19575670","PMID:20697559"],"direct_ancestors":[{"relation_name":"is_a","term_name":"signal sequence binding","termid":"GO:0005048"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0005048"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005048","GO:0005488"],"is_obsolete":false,"name":"ciliary targeting signal binding","synonyms":[{"name":"CTS binding","type":"exact"}],"termid":"GO:1990473"}


id: PBO:0053540
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 544","termid":"PBO:0053540"}


id: GO:1990742
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"An extracellular vesicle released from the plasma membrane and ranging in size from about 100 nm to 1000 nm.","definition_xrefs":["GOC:vesicles","PMID:24009894","Wikipedia:Microvesicles","PMID:22418571"],"direct_ancestors":[{"relation_name":"is_a","term_name":"extracellular vesicle","termid":"GO:1903561"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005576"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005576","GO:0005575"],"is_obsolete":false,"name":"microvesicle","synonyms":[{"name":"ectosome","type":"exact"},{"name":"extracellular microvesicle","type":"exact"},{"name":"shedding vesicle","type":"broad"}],"termid":"GO:1990742"}


id: MONDO:0024539
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any central areolar choroidal dystrophy in which the cause of the disease is a mutation in the GUCY2D gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"central areolar choroidal dystrophy","termid":"MONDO:0008982"},{"relation_name":"is_a","term_name":"neurovascular disorder","termid":"MONDO:0043218"},{"relation_name":"is_a","term_name":"GUCY2D-related dominant retinopathy","termid":"MONDO:0100441"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328","MONDO:0000426"],"is_obsolete":false,"name":"choroidal dystrophy, central areolar, 1","secondary_identifiers":["OMIM:215500","UMLS:C4551884","MEDGEN:1639900"],"synonyms":[{"name":"CACD1","type":"related"},{"name":"GUCY2D central areolar choroidal dystrophy","type":"exact"},{"name":"central areolar choroidal dystrophy caused by mutation in GUCY2D","type":"exact"},{"name":"choroidal dystrophy, central areolar","type":"related"},{"name":"choroidal dystrophy, central areolar 1","type":"exact"},{"name":"choroidal dystrophy, central areolar, 1","type":"exact"},{"name":"choroidal sclerosis","type":"related"}],"termid":"MONDO:0024539","xrefs":{"Monarch":{"xref_id":"0024539"}}}


id: PBO:0078647
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Lys (anticodon CTT) 2-3","termid":"PBO:0078647"}


id: MONDO:0003155
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A hemangioma characterized by the presence of cavernous vascular spaces.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hematopoietic and lymphoid system neoplasm","termid":"MONDO:0002334"},{"relation_name":"is_a","term_name":"vascular hemostatic disease","termid":"MONDO:0003159"},{"relation_name":"is_a","term_name":"hemangioma","termid":"MONDO:0006500"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"cavernous hemangioma","secondary_identifiers":["MESH:D006392","MEDGEN:9184","ICDO:9121/0","EFO:1000151","SCTID:416824008","MONDO:0006124","SCTID:56975005","NCIT:C3086","DOID:483","HP:0001048","UMLS:C0018920"],"synonyms":[{"name":"cavernoma","type":"exact"},{"name":"cavernous angioma","type":"exact"},{"name":"cavernous haemangioma","type":"exact"},{"name":"cavernous hemangioma","type":"exact"},{"name":"cavernous hemangioma (morphologic abnormality)","type":"exact"}],"termid":"MONDO:0003155","xrefs":{"Monarch":{"xref_id":"0003155"}}}


id: PBO:0029462
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_septum_location","termid":"PBO:0029462"}


id: RO:0002413
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"p1 directly provides input for p2 iff there exists some c such that p1 has_output c and p2 has_input c","direct_ancestors":[{"relation_name":"is_a","term_name":"immediately_causally_upstream_of","termid":"RO:0002412"},{"relation_name":"is_a","term_name":"transitively_provides_input_for","termid":"RO:0002414"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"directly_provides_input_for","termid":"RO:0002413"}


id: PBO:0041905
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cbl proto-oncogene","termid":"PBO:0041905"}


id: GO:0031299
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: pyruvate + taurine = L-alanine + sulfoacetaldehyde.","definition_xrefs":["RHEA:10420","PMID:11082195"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transaminase activity","termid":"GO:0008483"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016769"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0016769","GO:0016740","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"taurine-pyruvate aminotransferase activity","secondary_identifiers":["KEGG_REACTION:R05652","MetaCyc:TAURINE-AMINOTRANSFERASE-RXN","EC:2.6.1.77"],"synonyms":[{"name":"Tpa","type":"related"},{"name":"taurine:pyruvate aminotransferase activity","type":"related"}],"termid":"GO:0031299"}


id: MONDO:0021280
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A mucoepidermoid carcinoma that involves the parotid gland.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"major salivary gland mucoepidermoid carcinoma","termid":"MONDO:0006286"},{"relation_name":"is_a","term_name":"carcinoma of parotid gland","termid":"MONDO:0021331"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0004335"],"is_obsolete":false,"name":"mucoepidermoid carcinoma of parotid gland","secondary_identifiers":["icd11.foundation:135568040","NCIT:C5938","MEDGEN:277506","UMLS:C1335363","SCTID:423793008"],"synonyms":[{"name":"mucoepidermoid carcinoma of parotid","type":"exact"},{"name":"mucoepidermoid carcinoma of the parotid","type":"exact"},{"name":"mucoepidermoid carcinoma of the parotid gland","type":"exact"},{"name":"parotid gland mucoepidermoid carcinoma","type":"exact"},{"name":"parotid mucoepidermoid carcinoma","type":"exact"}],"termid":"MONDO:0021280","xrefs":{"Monarch":{"xref_id":"0021280"}}}


id: PBO:0016585
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"human ATXN10 ortholog","termid":"PBO:0016585"}


id: GO:1990802
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any protein phosphorylation that is required for DNA double-strand break processing.","definition_xrefs":["GOC:TermGenie","PMID:21841787","GO_REF:0000060","GOC:rb"],"gene_count":0,"genotype_count":0,"name":"obsolete protein phosphorylation involved in DNA double-strand break processing (obsolete GO:1990802)","synonyms":[{"name":"protein amino acid phosphorylation involved in DNA double-strand break processing","type":"exact"}],"termid":"GO:1990802"}


id: PR:Q9HDV1
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mug180 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9HDV1"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"steryl acetyl hydrolase mug81 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBPB2B2.02","synonyms":[{"name":"Spom972h-mug180","type":"exact"},{"name":"meiotically up-regulated gene 180 protein (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9HDV1"}


id: MONDO:0022338
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"histiocytosis","termid":"MONDO:0002637"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"ALK+ histiocytosis","synonyms":[{"name":"anaplastic lymphoma kinase positive histiocytosis","type":"related"}],"termid":"MONDO:0022338","xrefs":{"Monarch":{"xref_id":"0022338"}}}


id: PBO:0068186
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 493","termid":"PBO:0068186"}


id: GO:0030504
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of inorganic diphosphate across a membrane.","definition_xrefs":["PMID:11326272"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inorganic anion transmembrane transporter activity","termid":"GO:0015103"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0003674","GO:0022857","GO:0005215"],"is_obsolete":false,"name":"inorganic diphosphate transmembrane transporter activity","secondary_identifiers":["Reactome:R-HSA-5226964"],"synonyms":[{"name":"inorganic pyrophosphate transporter activity","type":"exact"}],"termid":"GO:0030504"}


id: PBO:0045371
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DPH5 divergent transcript","termid":"PBO:0045371"}


id: GO:0019367
data:
  {"annotated_genes":["SJAG_01356","SJAG_02885"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[79512,93827],"is_not":false,"summary":null,"term":"GO:0019367"}]},"cv_name":"biological_process","definition":"Elongation of a saturated fatty acid chain.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"fatty acid elongation","termid":"GO:0030497"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01356":null,"SJAG_02885":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0008150","GO:0044281","GO:0006629"],"is_obsolete":false,"name":"fatty acid elongation, saturated fatty acid","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["MetaCyc:FASYN-ELONG-PWY"],"termid":"GO:0019367","terms_by_termid":{"GO:0019367":null}}


id: PBO:0004233
data:
  {"annotation_feature_type":"gene","cv_name":"disease_associated","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hypercalciuric nephrolithiasis","termid":"PBO:0004233"}


id: FYPO:0003114
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of nitric oxide measured in a cell is higher than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased cellular reactive oxygen species level during vegetative growth","termid":"FYPO:0003004"},{"relation_name":"is_a","term_name":"altered cellular nitric oxide level","termid":"FYPO:0006408"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"increased cellular nitric oxide level during vegetative growth","synonyms":[{"name":"increased cellular NO level during vegetative growth","type":"exact"},{"name":"increased cellular nitric oxide level during mitotic cell cycle","type":"related"},{"name":"increased nitric oxide accumulation during vegetative growth","type":"related"}],"termid":"FYPO:0003114"}


id: PBO:0046302
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"engrailed homeobox 2","termid":"PBO:0046302"}


id: GO:0010824
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.","definition_xrefs":["GOC:tb","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of centrosome cycle","termid":"GO:0046605"},{"relation_name":"regulates","term_name":"centrosome duplication","termid":"GO:0051298"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0007049","GO:0008150"],"is_obsolete":false,"name":"regulation of centrosome duplication","termid":"GO:0010824"}


id: PR:P78753
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An asparagine synthetase [glutamine-hydrolyzing] that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO02567","PANTHER:PTHR11772:SF0"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"asparagine synthetase [glutamine-hydrolyzing] (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC119.10","secondary_identifiers":["UniProtKB:P78753"],"synonyms":[{"name":"Spom972h-ASNS","type":"exact"},{"name":"glutamine-dependent asparagine synthetase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:P78753"}


id: GO:0102608
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: tetracenomycin B3 + S-adenosyl-L-methionine = tetracenomycin E + S-adenosyl-L-homocysteine + H+.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete tetracenomycin B3 8-O-methyl transferase activity (obsolete GO:0102608)","termid":"GO:0102608"}


id: GO:0034035
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.","definition_xrefs":["GOC:mah","GOC:pde"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ribonucleoside bisphosphate metabolic process","termid":"GO:0033875"},{"relation_name":"is_a","term_name":"purine nucleoside bisphosphate metabolic process","termid":"GO:0034032"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0055086"],"is_obsolete":false,"name":"purine ribonucleoside bisphosphate metabolic process","synonyms":[{"name":"purine ribonucleoside bisphosphate metabolism","type":"exact"}],"termid":"GO:0034035"}


id: PBO:0028649
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_mRNA_splicing,_via_spliceosome","termid":"PBO:0028649"}


id: MONDO:0020475
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"ectodermal dysplasia syndrome","termid":"MONDO:0019287"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"dermotrichic syndrome","secondary_identifiers":["GARD:19683","Orphanet:99688","UMLS:C0795919","MEDGEN:1672480"],"termid":"MONDO:0020475","xrefs":{"Monarch":{"xref_id":"0020475"}}}


id: PBO:0062422
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 7 subfamily E member 83 pseudogene","termid":"PBO:0062422"}


id: FYPO:0004896
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more generation of precursor metabolites and energy RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Generation of precursor metabolites and energy RNAs are transcribed from genes whose products are involved in the formation of precursor metabolites and the liberation of energy from these substances.","definition_xrefs":["GO:0006091","PMID:25102102","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased RNA level during vegetative growth","termid":"FYPO:0000825"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0005447","FYPO:0001320","FYPO:0006551","FYPO:0000002"],"is_obsolete":false,"name":"increased level of generation of precursor metabolites and energy gene mRNA during vegetative growth","synonyms":[{"name":"increased generation of precursor metabolites and energy RNA accumulation during vegetative growth","type":"related"},{"name":"increased level of generation of precursor metabolites and energy RNA during mitotic cell cycle","type":"related"},{"name":"increased level of generation of precursor metabolites and energy gene RNA during vegetative growth","type":"exact"},{"name":"increased level of generation of precursor metabolites and energy transcripts during vegetative growth","type":"exact"}],"termid":"FYPO:0004896"}


id: MONDO:0019167
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A systemic IgA vasculitis that affects small vessels. It is characterized by skin purpura, arthritis, and abdominal and/or renal involvement.","definition_xrefs":["Orphanet:761"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete secondary glomerular disease (obsolete MONDO:0019724)","termid":"MONDO:0019724"},{"relation_name":"is_a","term_name":"hypersensitivity vasculitis","termid":"MONDO:0006794"},{"relation_name":"is_a","term_name":"immune complex mediated vasculitis","termid":"MONDO:0015491"},{"relation_name":"is_a","term_name":"necrotizing vasculitis","termid":"MONDO:0800113"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"immunoglobulin A vasculitis","secondary_identifiers":["DOID:11123","GARD:8204","NCIT:C34963","icd11.foundation:1629105375","SCTID:86074002","SCTID:191306005","ICD9:287.0","UMLS:C0034152","MEDGEN:48265","MESH:D011695"],"synonyms":[{"name":"HSP","type":"exact"},{"name":"Henoch Schonlein purpura","type":"related"},{"name":"Henoch-Schoenlein purpura","type":"exact"},{"name":"Henoch-Scholein purpura","type":"exact"},{"name":"Henoch-Schonlein purpura","type":"exact"},{"name":"IgA vasculitis","type":"exact"},{"name":"Schoenlein-Henoch purpura","type":"exact"},{"name":"allergic purpura","type":"exact"},{"name":"anaphylactoid purpura","type":"exact"},{"name":"autoimmune purpura","type":"exact"},{"name":"purpura rheumatica","type":"exact"},{"name":"purpura, Schonlein-Henoch","type":"related"},{"name":"purpura, autoimmune","type":"exact"},{"name":"rheumatoid purpura","type":"exact"},{"name":"vascular purpura","type":"related"}],"termid":"MONDO:0019167","xrefs":{"Monarch":{"xref_id":"0019167"}}}


id: FYPO:0004751
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of G418 than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased resistance to chemical during vegetative growth","termid":"FYPO:0000126"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0002682"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0000003"}],"interesting_parent_ids":["FYPO:0002682","FYPO:0000003","FYPO:0001985","FYPO:0000139","FYPO:0005447"],"is_obsolete":false,"name":"resistance to G418","synonyms":[{"name":"resistance to G418 during mitotic cell cycle","type":"related"},{"name":"resistance to G418 during vegetative growth","type":"exact"},{"name":"resistance to Geneticin","type":"exact"},{"name":"resistant to G418","type":"exact"}],"termid":"FYPO:0004751"}


id: GO:0019401
data:
  {"annotated_genes":["SJAG_00409","SJAG_01012"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[63830,70835],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006114"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbohydrate biosynthetic process","termid":"GO:0016051"},{"relation_name":"is_a","term_name":"alditol metabolic process","termid":"GO:0019400"},{"relation_name":"is_a","term_name":"polyol biosynthetic process","termid":"GO:0046173"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00409":null,"SJAG_01012":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0005975","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"alditol biosynthetic process","references_by_uniquename":{"GO_REF:0000117":null},"synonyms":[{"name":"alditol anabolism","type":"exact"},{"name":"alditol biosynthesis","type":"exact"},{"name":"alditol formation","type":"exact"},{"name":"alditol synthesis","type":"exact"}],"termid":"GO:0019401","terms_by_termid":{"GO:0006114":null}}


id: MONDO:0017353
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Neonatal glycine encephalopathy is a frequent, usually severe form of glycine encephalopathy (GE) characterized by coma, apnea, hypotonia, seizure and myoclonic jerks in the neonatal period, and subsequent developmental delay.","definition_xrefs":["Orphanet:289857"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glycine encephalopathy","termid":"MONDO:0011612"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004736"}],"interesting_parent_ids":["MONDO:0004736","MONDO:0005066"],"is_obsolete":false,"name":"neonatal glycine encephalopathy","secondary_identifiers":["NANDO:1200985","GARD:17332","icd11.foundation:414151121","MEDGEN:1785446","UMLS:C5548200"],"synonyms":[{"name":"classic glycine encephalopathy","type":"exact"},{"name":"neonatal NKH","type":"exact"},{"name":"neonatal non-ketotic hyperglycinemia","type":"exact"}],"termid":"MONDO:0017353","xrefs":{"Monarch":{"xref_id":"0017353"}}}


id: GO:0102447
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine = H+ + rhamnacene + S-adenosyl-L-homocysteine.","definition_xrefs":["RHEA:73271"],"direct_ancestors":[{"relation_name":"is_a","term_name":"methyltransferase activity","termid":"GO:0008168"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0016740","GO:0016741","GO:0003674"],"is_obsolete":false,"name":"rhamnetin 3'-O-methyltransferase activity","secondary_identifiers":["MetaCyc:RXN-13933"],"termid":"GO:0102447"}


id: GO:0120281
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A lipid bilayer that surrounds an autolysosome, a single-membrane-bounded vesicle in which endogenous cellular material is degraded.","definition_xrefs":["GOC:nhn","PMID:32047650","PMID:17182262","GOC:krc","PMID:24657946","PMID:26382870"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lysosomal membrane","termid":"GO:0005765"},{"relation_name":"part_of","term_name":"autolysosome","termid":"GO:0044754"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005773"}],"interesting_parent_ids":["GO:0005737","GO:0005575","GO:0005773"],"is_obsolete":false,"name":"autolysosome membrane","termid":"GO:0120281"}


id: PBO:0070185
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U7 small nuclear 103 pseudogene","termid":"PBO:0070185"}


id: GO:1902554
data:
  {"annotated_genes":["SJAG_00758","SJAG_03618","SJAG_04420","SJAG_02441","SJAG_03421","SJAG_00150","SJAG_04614","SJAG_04502","SJAG_01149","SJAG_03048","SJAG_04312","SJAG_01401","SJAG_00995","SJAG_03967","SJAG_05978","SJAG_03525","SJAG_00973","SJAG_00100","SJAG_01274","SJAG_00901","SJAG_04232","SJAG_03931","SJAG_01716","SJAG_02404","SJAG_00512","SJAG_03695","SJAG_03061","SJAG_01245","SJAG_04140","SJAG_02057","SJAG_05017","SJAG_00439","SJAG_03591","SJAG_04368","SJAG_01213","SJAG_01207","SJAG_03206","SJAG_03699","SJAG_03160","SJAG_01799","SJAG_00142"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[72620,74038,81502,119817,74328],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990316"},{"annotations":[72731,75109],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005952"},{"annotations":[112893,97700,81262],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070692"},{"annotations":[106259,110319,75831,76740,72303,78496,90074,80063,104277,107641,108212,71946,73266],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000307"},{"annotations":[77234,114016],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031431"},{"annotations":[110846,111003],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070691"},{"annotations":[75947,77792,79890],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005956"},{"annotations":[72120,71894,77934,110951,80501,116827,76148,94052],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005675"},{"annotations":[61406,67348,77990],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0070985"}]},"cv_name":"cellular_component","definition":"A protein complex which is capable of protein serine/threonine kinase activity.","definition_xrefs":["GOC:bhm","PMID:18191223","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein kinase complex","termid":"GO:1902911"}],"gene_count":41,"genes_by_uniquename":{"SJAG_00100":null,"SJAG_00142":null,"SJAG_00150":null,"SJAG_00439":null,"SJAG_00512":null,"SJAG_00758":null,"SJAG_00901":null,"SJAG_00973":null,"SJAG_00995":null,"SJAG_01149":null,"SJAG_01207":null,"SJAG_01213":null,"SJAG_01245":null,"SJAG_01274":null,"SJAG_01401":null,"SJAG_01716":null,"SJAG_01799":null,"SJAG_02057":null,"SJAG_02404":null,"SJAG_02441":null,"SJAG_03048":null,"SJAG_03061":null,"SJAG_03160":null,"SJAG_03206":null,"SJAG_03421":null,"SJAG_03525":null,"SJAG_03591":null,"SJAG_03618":null,"SJAG_03695":null,"SJAG_03699":null,"SJAG_03931":null,"SJAG_03967":null,"SJAG_04140":null,"SJAG_04232":null,"SJAG_04312":null,"SJAG_04368":null,"SJAG_04420":null,"SJAG_04502":null,"SJAG_04614":null,"SJAG_05017":null,"SJAG_05978":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"serine/threonine protein kinase complex","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null,"GO_REF:0000117":null},"synonyms":[{"name":"PDR16 complex dimer","type":"related"},{"name":"PDR16 complex homodimer","type":"related"}],"termid":"GO:1902554","terms_by_termid":{"GO:0000307":null,"GO:0005675":null,"GO:0005952":null,"GO:0005956":null,"GO:0031431":null,"GO:0070691":null,"GO:0070692":null,"GO:0070985":null,"GO:1990316":null}}


id: PBO:0069742
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1023, pseudogene","termid":"PBO:0069742"}


id: GO:0030689
data:
  {"annotated_genes":["SJAG_04346","SJAG_01494","SJAG_00311","SJAG_03654","SJAG_01275","SJAG_00838"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[74631,99792,81950],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0030690"},{"annotations":[114425,74632,81951],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0030691"},{"annotations":[74578,80439],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0030692"}]},"cv_name":"cellular_component","definition":"Any of several heterodimers containing one or two Noc proteins, associated with preribosomal complexes; involved in ribosome biogenesis.","definition_xrefs":["PMID:12446671"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nuclear protein-containing complex","termid":"GO:0140513"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00311":null,"SJAG_00838":null,"SJAG_01275":null,"SJAG_01494":null,"SJAG_03654":null,"SJAG_04346":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005634"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0032991","GO:0005575","GO:0005634"],"is_obsolete":false,"name":"Noc complex","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0030689","terms_by_termid":{"GO:0030690":null,"GO:0030691":null,"GO:0030692":null}}


id: GO:0021830
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of interneurons from the subpallium to the cortex during forebrain development.","definition_xrefs":["GO_REF:0000021","PMID:12626695","GOC:jid","GOC:dph","GOC:cls","GOC:dgh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"substrate-independent telencephalic tangential interneuron migration","termid":"GO:0021843"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"interneuron migration from the subpallium to the cortex","termid":"GO:0021830"}


id: PATO:0002432
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A shape that is in the form of a spade.","definition_xrefs":["PATOC:WC"],"direct_ancestors":[{"relation_name":"is_a","term_name":"shape","termid":"PATO:0000052"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spade-shaped","termid":"PATO:0002432"}


id: MONDO:1010484
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Tetralogy of fallot that occurs in horse.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tetralogy of fallot, non-human animal","termid":"MONDO:1010021"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tetralogy of fallot, horse","secondary_identifiers":["OMIA:000994-9796"],"termid":"MONDO:1010484","xrefs":{"Monarch":{"xref_id":"1010484"}}}


id: PBO:0043586
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"collagen type XVIII alpha 1 chain","termid":"PBO:0043586"}


id: GO:0019218
data:
  {"annotated_genes":["SJAG_02104","SJAG_04018","SJAG_01307","SJAG_02044"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[95766],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010895"},{"annotations":[111827],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070452"},{"annotations":[77263],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0045540"},{"annotations":[90426,107790],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0032443"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of lipid metabolic process","termid":"GO:0019216"},{"relation_name":"regulates","term_name":"steroid metabolic process","termid":"GO:0008202"}],"gene_count":4,"genes_by_uniquename":{"SJAG_01307":null,"SJAG_02044":null,"SJAG_02104":null,"SJAG_04018":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0008150","GO:0006629"],"is_obsolete":false,"name":"regulation of steroid metabolic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"regulation of steroid metabolism","type":"exact"}],"termid":"GO:0019218","terms_by_termid":{"GO:0010895":null,"GO:0032443":null,"GO:0045540":null,"GO:0070452":null}}


id: GO:0010212
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.","definition_xrefs":["PMID:12509526"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to radiation","termid":"GO:0009314"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to ionizing radiation","synonyms":[{"name":"response to ionising radiation","type":"exact"},{"name":"response to ionizing radiation stimulus","type":"exact"}],"termid":"GO:0010212"}


id: MONDO:0002531
data:
  {"annotated_genes":["SJAG_04213","SJAG_01111","SJAG_02855","SJAG_03453"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87156],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010621"},{"annotations":[88631],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0044792"},{"annotations":[87708],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008097"},{"annotations":[87287],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009578"},{"annotations":[86848],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008093"},{"annotations":[89170,89169],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0024517"}]},"cv_name":"mondo","definition":"A benign or malignant tumor involving the skin. Representative examples of benign skin neoplasms include the benign melanocytic skin nevus, acanthoma, sebaceous adenoma, sweat gland adenoma, lipoma, hemangioma, fibroma, and benign fibrous histiocytoma. Representative examples of malignant skin neoplasms include basal cell carcinoma, squamous cell carcinoma, melanoma, and Kaposi sarcoma.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neoplasm","termid":"MONDO:0005070"},{"relation_name":"is_a","term_name":"skin disorder","termid":"MONDO:0005093"}],"gene_count":4,"genes_by_uniquename":{"SJAG_01111":null,"SJAG_02855":null,"SJAG_03453":null,"SJAG_04213":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"skin neoplasm","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["NCIT:C3372","SCTID:126488004","ONCOTREE:SKIN","ICD9:239.2","MEDGEN:19993","MESH:D012878","EFO:0004198","UMLS:C0037286","DOID:3165"],"synonyms":[{"name":"neoplasm of skin","type":"exact"},{"name":"neoplasm of skin by site","type":"exact"},{"name":"neoplasm of the skin","type":"exact"},{"name":"neoplasm of zone of skin","type":"exact"},{"name":"skin","type":"related"},{"name":"skin benign neoplasm","type":"related"},{"name":"skin neoplasm","type":"exact"},{"name":"skin neoplasms","type":"exact"},{"name":"skin tumor","type":"exact"},{"name":"skin tumour","type":"exact"},{"name":"tumor of skin","type":"exact"},{"name":"tumor of the skin","type":"exact"},{"name":"tumor of zone of skin","type":"exact"},{"name":"tumour of skin","type":"exact"},{"name":"tumour of the skin","type":"exact"},{"name":"tumour of zone of skin","type":"exact"},{"name":"zone of skin neoplasm","type":"exact"},{"name":"zone of skin neoplasm (disease)","type":"exact"},{"name":"zone of skin tumor","type":"exact"},{"name":"zone of skin tumour","type":"exact"}],"termid":"MONDO:0002531","terms_by_termid":{"MONDO:0008093":null,"MONDO:0008097":null,"MONDO:0009578":null,"MONDO:0010621":null,"MONDO:0024517":null,"MONDO:0044792":null},"xrefs":{"Monarch":{"xref_id":"0002531"}}}


id: PBO:0085101
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Nuclear protein of unknown function; relocalizes to the cytosol in response to hypoxia; contains WD-40 domains; not an essential gene; protein abundance increases in response to DNA replication stress","termid":"PBO:0085101"}


id: PBO:0066663
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"receptor interacting serine/threonine kinase 4","termid":"PBO:0066663"}


id: GO:0038066
data:
  {"annotated_genes":["SJAG_02135","SJAG_02183","SJAG_03893","SJAG_03903","SJAG_03384","SJAG_02000","SJAG_02013","SJAG_01718","SJAG_06622","SJAG_02592","SJAG_04825","SJAG_05000","SJAG_06592","SJAG_00318","SJAG_04777","SJAG_00027","SJAG_01587","SJAG_02945","SJAG_01199","SJAG_03828","SJAG_02342","SJAG_00117","SJAG_03185","SJAG_06621"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[59334,71824,74890,96257,103687,108232],"is_not":false,"summary":null,"term":"GO:0038066"},{"annotations":[97874,101357,119090,120347,96934,93548],"is_not":false,"rel_names":["negatively_regulates","regulates"],"summary":null,"term":"GO:1903753"},{"annotations":[110915,119382,113805,110911,110910,114471,97160,110916,120310,110912,110913,110914],"is_not":false,"rel_names":["regulates","positively_regulates"],"summary":null,"term":"GO:1900745"}]},"cv_name":"biological_process","definition":"A MAPK cascade containing at least the p38MAPK (MAPK14) MAP kinase, or Hog1 in yeast. It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and of p38MAPK. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier. The p38MAPK cascade is activated by stress signals, including hyperosmolarity, as well as by G protein-coupled receptors, growth factors, and cytokines, and results in cellular responses such as cell proliferation, cell differentiation, apoptosis and inflammation.","definition_xrefs":["PMID:32794416","PMID:20811974","PMID:23125017"],"direct_ancestors":[{"relation_name":"is_a","term_name":"MAPK cascade","termid":"GO:0000165"}],"gene_count":24,"genes_by_uniquename":{"SJAG_00027":null,"SJAG_00117":null,"SJAG_00318":null,"SJAG_01199":null,"SJAG_01587":null,"SJAG_01718":null,"SJAG_02000":null,"SJAG_02013":null,"SJAG_02135":null,"SJAG_02183":null,"SJAG_02342":null,"SJAG_02592":null,"SJAG_02945":null,"SJAG_03185":null,"SJAG_03384":null,"SJAG_03828":null,"SJAG_03893":null,"SJAG_03903":null,"SJAG_04777":null,"SJAG_04825":null,"SJAG_05000":null,"SJAG_06592":null,"SJAG_06621":null,"SJAG_06622":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"p38MAPK cascade","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null,"GO_REF:0000117":null},"secondary_identifiers":["Reactome:R-HSA-450302"],"synonyms":[{"name":"MAPK14 cascade","type":"related"},{"name":"osmosensory signaling MAPK cascade","type":"narrow"},{"name":"p38 MAPK cascade","type":"exact"},{"name":"p38 cascade","type":"exact"}],"termid":"GO:0038066","terms_by_termid":{"GO:0038066":null,"GO:1900745":null,"GO:1903753":null}}


id: PBO:0075808
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"single stranded DNA binding protein 1","termid":"PBO:0075808"}


id: PBO:0051699
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"inositol polyphosphate-4-phosphatase type I A","termid":"PBO:0051699"}


id: PBO:0077786
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA topoisomerase II beta","termid":"PBO:0077786"}


id: PBO:0039402
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"anaphase promoting complex subunit 2","termid":"PBO:0039402"}


id: PBO:0013792
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"IRC1-L/borderline left","termid":"PBO:0013792"}


id: MONDO:0022822
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"congenital cardiovascular shunt","secondary_identifiers":["MEDGEN:108904","UMLS:C0596366"],"termid":"MONDO:0022822","xrefs":{"Monarch":{"xref_id":"0022822"}}}


id: PBO:0091812
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP citrate synthase subunit 1","termid":"PBO:0091812"}


id: GO:0097515
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A specialized envelope lying outside the cell membrane of a spore derived from an asexual process. Examples of this process are found in bacterial and fungal species.","definition_xrefs":["GOC:mah","GOC:cjm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"spore wall","termid":"GO:0031160"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0005618"}],"interesting_parent_ids":["GO:0005618","GO:0005575"],"is_obsolete":false,"name":"asexual spore wall","termid":"GO:0097515"}


id: PBO:0056581
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MCTS family member 2","termid":"PBO:0056581"}


id: GO:0098771
data:
  {"annotated_genes":["SJAG_01694","SJAG_03850","SJAG_04677","SJAG_03624","SJAG_01435","SJAG_02399","SJAG_04111","SJAG_04698","SJAG_04867","SJAG_01541","SJAG_03862","SJAG_04757","SJAG_01078","SJAG_03793","SJAG_02457","SJAG_02080","SJAG_02883","SJAG_04403","SJAG_02834","SJAG_04028","SJAG_03644","SJAG_02532","SJAG_04096","SJAG_03519","SJAG_00916","SJAG_02474","SJAG_00244","SJAG_01353","SJAG_02968","SJAG_02735","SJAG_00222","SJAG_04675","SJAG_01400","SJAG_04167","SJAG_00232","SJAG_00822","SJAG_01004","SJAG_00923","SJAG_03516","SJAG_00668","SJAG_04032","SJAG_01713","SJAG_01990","SJAG_04743","SJAG_04185","SJAG_04031","SJAG_03401","SJAG_03061","SJAG_00328","SJAG_03879","SJAG_03528","SJAG_03631","SJAG_01803","SJAG_04892","SJAG_02240","SJAG_03667","SJAG_05325","SJAG_03866","SJAG_02019","SJAG_00802","SJAG_00532","SJAG_04607","SJAG_02578","SJAG_04870","SJAG_04584","SJAG_01007","SJAG_02847","SJAG_04242","SJAG_04760","SJAG_00792","SJAG_01000"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[95995,59554,102410,114786,79495],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0010106"},{"annotations":[75176],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0055064"},{"annotations":[72546],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0032468"},{"annotations":[120604,75420,81972,75274,110769,71874,73196,74179,82019,100022,101837,80195,115353,72842,75354,76931],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006874"},{"annotations":[109812,102082,95017,79821,76810],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006878"},{"annotations":[94185,95941,79822,76040,59207,79962,72923,106193,77527,76811],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006879"},{"annotations":[76253,72058],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010961"},{"annotations":[77525,75456],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0030026"},{"annotations":[109534,109653,117049,63992,104530,111005,94017,90577,104529,99095,104528],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0030643"},{"annotations":[101838,79880,72424,97339,73982],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0030007"},{"annotations":[77678,106248,105507,80090,96619,76507,75944,78968,106108,102083,74561,116342],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006882"},{"annotations":[105719],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033212"},{"annotations":[115204],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0098711"},{"annotations":[57632],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010960"},{"annotations":[75177],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0055075"},{"annotations":[94330,79493],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033215"},{"annotations":[62566,62894,71068],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033214"}]},"cv_name":"biological_process","definition":"Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chemical 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ion homeostasis","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null,"GO_REF:0000108":null,"GO_REF:0000117":null},"termid":"GO:0098771","terms_by_termid":{"GO:0006874":null,"GO:0006878":null,"GO:0006879":null,"GO:0006882":null,"GO:0010106":null,"GO:0010960":null,"GO:0010961":null,"GO:0030007":null,"GO:0030026":null,"GO:0030643":null,"GO:0032468":null,"GO:0033212":null,"GO:0033214":null,"GO:0033215":null,"GO:0055064":null,"GO:0055075":null,"GO:0098711":null}}


id: GO:0032764
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell cytokine production.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cytokine production involved in immune response","termid":"GO:0002719"},{"relation_name":"is_a","term_name":"regulation of mast cell cytokine production","termid":"GO:0032763"},{"relation_name":"negatively_regulates","term_name":"mast cell cytokine production","termid":"GO:0032762"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0010467"},{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"negative regulation of mast cell cytokine production","synonyms":[{"name":"down regulation of mast cell cytokine production","type":"exact"},{"name":"down-regulation of mast cell cytokine production","type":"exact"},{"name":"downregulation of mast cell cytokine production","type":"exact"},{"name":"inhibition of mast cell cytokine production","type":"narrow"}],"termid":"GO:0032764"}


id: SO:0001211
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"The region of mRNA 1 base long that is skipped during the process of translational frameshifting (GO:0006452), causing the reading frame to be different.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"translational_frameshift","termid":"SO:0001210"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"plus_1_translational_frameshift","synonyms":[{"name":"plus 1 ribosomal frameshift","type":"exact"},{"name":"plus 1 translational frameshift","type":"exact"}],"termid":"SO:0001211"}


id: GO:0052787
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltopentaose.","definition_xrefs":["PMID:9406414","GOC:mengo_curators","PMID:7511484"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polysaccharide catabolic process","termid":"GO:0000272"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0005975","GO:0008150"],"is_obsolete":false,"name":"alpha-linked polysaccharide catabolism to maltopentaose","synonyms":[{"name":"alpha-amylase-mediated polysaccharide catabolism, producing maltopentaose","type":"exact"},{"name":"maltopentaose-forming alpha-amylase activity","type":"related"}],"termid":"GO:0052787"}


id: PBO:0039786
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aquaporin 12B","termid":"PBO:0039786"}


id: MONDO:0017279
data:
  {"annotated_genes":["SJAG_04545","SJAG_16459","SJAG_01229","SJAG_02106","SJAG_00063","SJAG_03866","SJAG_04404","SJAG_04757"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87618,87617],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014796"},{"annotations":[88019,88018],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011658"},{"annotations":[87627,87626],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014233"},{"annotations":[88780,88781],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011706"}]},"cv_name":"mondo","definition":"A form of Parkinson disease (PD) characterized by an age of onset between 21-45 years, rigidity, painful cramps followed by tremor, bradykinesia, dystonia, gait complaints and falls, and other non-motor symptoms. A slow disease progression and a more pronounced response to dopaminergic therapy are also observed in most YOPD forms.","definition_xrefs":["Orphanet:2828"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"primary orthostatic hypotension","termid":"MONDO:0015914"},{"relation_name":"is_a","term_name":"Parkinson disease","termid":"MONDO:0005180"}],"gene_count":8,"genes_by_uniquename":{"SJAG_00063":null,"SJAG_01229":null,"SJAG_02106":null,"SJAG_03866":null,"SJAG_04404":null,"SJAG_04545":null,"SJAG_04757":null,"SJAG_16459":null},"genotype_count":0,"is_obsolete":false,"name":"young-onset Parkinson disease","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["DOID:0060894","GARD:16610","MEDGEN:907947","SCTID:715345007","UMLS:C4275179"],"synonyms":[{"name":"YOPD","type":"exact"},{"name":"early-onset Parkinson disease","type":"exact"},{"name":"early-onset Parkinson's disease","type":"related"}],"termid":"MONDO:0017279","terms_by_termid":{"MONDO:0011658":null,"MONDO:0011706":null,"MONDO:0014233":null,"MONDO:0014796":null},"xrefs":{"Monarch":{"xref_id":"0017279"}}}


id: FYPO:0003929
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which spores germinate to a lower extent than wild type following exposure to ionizing radiation.","definition_xrefs":["PMID:24847916","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal cell phenotype","termid":"FYPO:0003037"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"spores sensitive to ionizing radiation","synonyms":[{"name":"sensitive to ionizing radiation in the spore phase","type":"exact"},{"name":"spores sensitive to IR","type":"exact"}],"termid":"FYPO:0003929"}


id: PBO:0061624
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nudix hydrolase 8","termid":"PBO:0061624"}


id: PATO:0001663
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A solubility which is relatively high.","definition_xrefs":["PATO:GVG"],"direct_ancestors":[{"relation_name":"increased_in_magnitude_relative_to","term_name":"normal","termid":"PATO:0000461"},{"relation_name":"is_a","term_name":"soluble in","termid":"PATO:0001537"},{"relation_name":"is_a","term_name":"increased object quality","termid":"PATO:0002305"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"increased solubility","synonyms":[{"name":"high solubility","type":"exact"}],"termid":"PATO:0001663"}


id: _global:excluded_subClassOf
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"excluded_subClassOf","termid":"_global:excluded_subClassOf","xrefs":{"Monarch":{"xref_id":"excluded_subClassOf"}}}


id: MOD:01614
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts a glycine residue to glycyl phospho-5'-adenosine.","definition_xrefs":["RESID:AA0511","PubMed:16388576","PubMed:9632726"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified glycine residue","termid":"MOD:00908"},{"relation_name":"is_a","term_name":"adenylated residue","termid":"MOD:01165"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glycyl phospho-5'-adenosine","synonyms":[{"name":"(2-aminoacetyl)oxy-([(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy)phosphinic acid","type":"exact"},{"name":"([(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl)-2-aminoethanoate","type":"exact"},{"name":"5'-adenylic-glyinate","type":"exact"},{"name":"MOD_RES Glycyl adenylate","type":"exact"},{"name":"aminoacetyl [5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl hydrogen phosphate","type":"exact"},{"name":"glycine monoanhydride with 5'-adenylic acid","type":"exact"},{"name":"glycyl 5'-adenylate","type":"exact"},{"name":"glycyl adenosine-5'-phosphate","type":"exact"},{"name":"glycyl phospho-5'-adenosine","type":"exact"},{"name":"glycyladenylate","type":"exact"}],"termid":"MOD:01614"}


id: PBO:0027435
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_protein_localization_to_medial_cortical_node","termid":"PBO:0027435"}


id: PBO:0062382
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 7 subfamily D member 11 pseudogene","termid":"PBO:0062382"}


id: MONDO:0015585
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Cryptogenic late-onset epileptic spasms is a rare epilepsy syndrome characterized by late-onset (after 1 year old) epileptic spasms that occur in clusters, associated with tonic seizures, atypical absences and cognitive deterioration. Language difficulties and behavior problems are frequently present. EEG is characterized by a temporal, or temporofrontal, slow wave or spike focus combined with synchronous spike-waves and no hypsarrhythmia or background activity.","definition_xrefs":["Orphanet:163708"],"direct_ancestors":[{"relation_name":"is_a","term_name":"childhood-onset epilepsy syndrome","termid":"MONDO:0020072"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027"],"is_obsolete":false,"name":"cryptogenic late-onset epileptic spasms","secondary_identifiers":["UMLS:C4755310","GARD:20050","icd11.foundation:457378168","MEDGEN:1666207"],"synonyms":[{"name":"late-onset infantile spasms","type":"exact"}],"termid":"MONDO:0015585","xrefs":{"Monarch":{"xref_id":"0015585"}}}


id: PBO:0072702
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RuvB like AAA ATPase 2","termid":"PBO:0072702"}


id: PBO:0052493
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"KLHL6 antisense RNA 1","termid":"PBO:0052493"}


id: PBO:0041580
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 22 open reading frame 15","termid":"PBO:0041580"}


id: MONDO:0017739
data:
  {"annotated_genes":["SJAG_00108","SJAG_02453"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87951],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014885"},{"annotations":[87805],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011997"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"inborn errors of metabolism","termid":"MONDO:0019052"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00108":null,"SJAG_02453":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066"],"is_obsolete":false,"name":"disorder of lysosomal-related organelles","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:21334","Orphanet:309340","MEDGEN:1826110","UMLS:C5681043"],"termid":"MONDO:0017739","terms_by_termid":{"MONDO:0011997":null,"MONDO:0014885":null},"xrefs":{"Monarch":{"xref_id":"0017739"}}}


id: GO:0042960
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of antimonite from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"antimonite transmembrane transporter activity","termid":"GO:0015104"},{"relation_name":"is_a","term_name":"secondary active transmembrane transporter activity","termid":"GO:0015291"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0005215","GO:0003674","GO:0022857"],"is_obsolete":false,"name":"antimonite secondary active transmembrane transporter activity","synonyms":[{"name":"antimonite porter activity","type":"related"}],"termid":"GO:0042960"}


id: PBO:0076899
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"testis expressed 53","termid":"PBO:0076899"}


id: GO:0032057
data:
  {"annotated_genes":["SJAG_01942","SJAG_03869","SJAG_00690","SJAG_00169","SJAG_02592","SJAG_00786"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[71694,117620,96253,101250,77010,111648],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990625"}]},"cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of translational initiation","termid":"GO:0045947"},{"relation_name":"part_of","term_name":"response to stress","termid":"GO:0006950"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00169":null,"SJAG_00690":null,"SJAG_00786":null,"SJAG_01942":null,"SJAG_02592":null,"SJAG_03869":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"negatively_regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"negative regulation of translational initiation in response to stress","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"down regulation of translation initiation in response to stress","type":"exact"},{"name":"down-regulation of translation initiation in response to stress","type":"exact"},{"name":"downregulation of translation initiation in response to stress","type":"exact"},{"name":"inhibition of translation initiation in response to stress","type":"narrow"}],"termid":"GO:0032057","terms_by_termid":{"GO:1990625":null}}


id: GO:0061922
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: propionyl-CoA + histone = CoA + propionyl-histone.","definition_xrefs":["PMID:17267393"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein propionyltransferase activity","termid":"GO:0061920"},{"relation_name":"is_a","term_name":"histone modifying activity","termid":"GO:0140993"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0016740","GO:0003824","GO:0140096","GO:0016746"],"is_obsolete":false,"name":"histone propionyltransferase activity","termid":"GO:0061922"}


id: PR:Q9UUI2
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- shf1 gene.","definition_xrefs":["UniProtKB:Q9UUI2","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small histone ubiquitination factor 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC22F8.12c","synonyms":[{"name":"Spom972h-shf1","type":"exact"}],"termid":"PR:Q9UUI2"}


id: PBO:0049053
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"G protein-coupled receptor 52","termid":"PBO:0049053"}


id: GO:0050125
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: N-benzyloxycarbonylglycine + H2O + H+ = benzyl alcohol + CO2 + glycine.","definition_xrefs":["EC:3.5.1.58","RHEA:20900"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides","termid":"GO:0016811"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0016810"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0016787","GO:0003824","GO:0016810"],"is_obsolete":false,"name":"N-benzyloxycarbonylglycine hydrolase activity","secondary_identifiers":["KEGG_REACTION:R02551","MetaCyc:N-BENZYLOXYCARBONYLGLYCINE-HYDROLASE-RXN"],"synonyms":[{"name":"N-benzyloxycarbonylglycine urethanehydrolase activity","type":"related"},{"name":"benzyloxycarbonylglycine hydrolase activity","type":"related"},{"name":"nalpha-benzyloxycarbonyl amino acid urethane hydrolase I","type":"related"},{"name":"nalpha-benzyloxycarbonyl amino acid urethane hydrolase activity","type":"related"},{"name":"nalpha-carbobenzoxyamino acid amidohydrolase activity","type":"related"}],"termid":"GO:0050125"}


id: PATO:0001250
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A color consisting of green hue and high brightness.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"green","termid":"PATO:0000320"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"light green","termid":"PATO:0001250"}


id: MONDO:0022930
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Dandy-Walker syndrome","termid":"MONDO:0009072"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0020022"}],"interesting_parent_ids":["MONDO:0020022"],"is_obsolete":false,"name":"Dandy-Walker malformation with nasopharyngeal teratoma and diaphragmatic hernia","secondary_identifiers":["UMLS:C2931823","GARD:137","MESH:C538340","MEDGEN:419910"],"synonyms":[{"name":"Aughton sloan Milad syndrome","type":"exact"}],"termid":"MONDO:0022930","xrefs":{"Monarch":{"xref_id":"0022930"}}}


id: PBO:0058083
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MIR4300 host gene","termid":"PBO:0058083"}


id: GO:2000623
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of mRNA catabolic process","termid":"GO:1902373"},{"relation_name":"is_a","term_name":"regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","termid":"GO:2000622"},{"relation_name":"negatively_regulates","term_name":"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","termid":"GO:0000184"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0016071"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0016071"},{"rel_name":"positively_regulates","termid":"GO:0010467"},{"rel_name":"regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0016071","GO:0010467","GO:0008150"],"is_obsolete":false,"name":"negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","synonyms":[{"name":"negative regulation of mRNA breakdown, nonsense-mediated decay","type":"exact"},{"name":"negative regulation of mRNA catabolic process, nonsense-mediated","type":"exact"},{"name":"negative regulation of mRNA catabolism, nonsense-mediated","type":"exact"},{"name":"negative regulation of mRNA degradation, nonsense-mediated decay","type":"exact"},{"name":"negative regulation of nonsense-mediated mRNA decay","type":"exact"},{"name":"negative regulation of nuclear mRNA catabolic process, nonsense-mediated decay","type":"exact"}],"termid":"GO:2000623"}


id: PBO:0080498
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"von Willebrand factor pseudogene 1","termid":"PBO:0080498"}


id: PBO:0068727
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U4atac small nuclear 16, pseudogene","termid":"PBO:0068727"}


id: PBO:0069897
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1188, pseudogene","termid":"PBO:0069897"}


id: MONDO:0005605
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign papillary neoplasm composed of transitional cells which show preservation of the nuclear polarity.","definition_xrefs":["NCIT:C4115"],"direct_ancestors":[{"relation_name":"is_a","term_name":"papilloma","termid":"MONDO:0002363"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transitional cell papilloma","secondary_identifiers":["UMLS:C0334266","DOID:2670","EFO:0006497","ICDO:8120/0","MEDGEN:137734"],"synonyms":[{"name":"papilloma, transitional cell, benign","type":"exact"},{"name":"transitional cell papilloma","type":"exact"},{"name":"transitional cell papilloma NOS (morphologic abnormality)","type":"exact"},{"name":"transitional cell papilloma, benign","type":"exact"},{"name":"transitional cell papilloma, benign (morphologic abnormality)","type":"exact"},{"name":"transitional papilloma","type":"exact"}],"termid":"MONDO:0005605","xrefs":{"Monarch":{"xref_id":"0005605"}}}


id: PBO:0063110
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"prostate androgen-regulated mucin-like protein 1","termid":"PBO:0063110"}


id: PR:Q9P6I1
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- ubc16 gene.","definition_xrefs":["UniProtKB:Q9P6I1","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin-conjugating enzyme E2 16 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC1198.09","synonyms":[{"name":"E2 ubiquitin-conjugating enzyme 16 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-ubc16","type":"exact"},{"name":"ubiquitin carrier protein 16 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"ubiquitin-protein ligase 16 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9P6I1"}


id: PBO:0067147
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 197, pseudogene","termid":"PBO:0067147"}


id: PBO:0059877
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myotubularin related protein 14","termid":"PBO:0059877"}


id: MONDO:0001497
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"male reproductive system disorder","termid":"MONDO:0003150"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"male genital organ vascular disease","secondary_identifiers":["ICD9:608.83","SCTID:198057005","UMLS:C0042374","MEDGEN:508280","DOID:12335"],"synonyms":[{"name":"vascular disorder of male genital organs","type":"exact"}],"termid":"MONDO:0001497","xrefs":{"Monarch":{"xref_id":"0001497"}}}


id: GO:0060244
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the rate or extent of cell proliferation in response to cell density.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cell population proliferation","termid":"GO:0008285"},{"relation_name":"part_of","term_name":"contact inhibition","termid":"GO:0060242"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of cell proliferation involved in contact inhibition","termid":"GO:0060244"}


id: GO:0001756
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.","definition_xrefs":["ISBN:0721662544"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anterior/posterior pattern specification","termid":"GO:0009952"},{"relation_name":"is_a","term_name":"segmentation","termid":"GO:0035282"},{"relation_name":"is_a","term_name":"anatomical structure formation involved in morphogenesis","termid":"GO:0048646"},{"relation_name":"part_of","term_name":"chordate embryonic development","termid":"GO:0043009"},{"relation_name":"part_of","term_name":"somite development","termid":"GO:0061053"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"somitogenesis","secondary_identifiers":["Reactome:R-HSA-9824272","Wikipedia:Somitogenesis"],"synonyms":[{"name":"formation of mesodermal clusters","type":"exact"}],"termid":"GO:0001756"}


id: PBO:0081518
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ZNF426 divergent transcript","termid":"PBO:0081518"}


id: RO:0002159
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","direct_ancestors":[{"relation_name":"is_a","term_name":"evolutionarily_related_to","termid":"RO:0002320"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serially_homologous_to","termid":"RO:0002159"}


id: MONDO:0012330
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Talo-patello-scaphoid osteolysis is an extremely rare form of primary osteolysis, described in two sisters to date, characterized by bilateral osteolysis of the tali, scaphoids, and patellae (accompanied by periarticular swelling and pain) and short fourth metacarpals (brachydactyly type E), in the absence of renal disease. Autosomal recessive inheritance has been suggested.","definition_xrefs":["Orphanet:50809"],"direct_ancestors":[{"relation_name":"is_a","term_name":"primary osteolysis","termid":"MONDO:0019707"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"talo-patello-scaphoid osteolysis","secondary_identifiers":["MESH:C536894","OMIM:609655","MEDGEN:400611","UMLS:C1864784","icd11.foundation:1276091756","GARD:10061"],"synonyms":[{"name":"singh-Williams-McAlister syndrome","type":"exact"},{"name":"talo-patello-scaphoid osteolysis, synovitis, and short fourth metacarpals","type":"related"}],"termid":"MONDO:0012330","xrefs":{"Monarch":{"xref_id":"0012330"}}}


id: PBO:0078030
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T cell receptor alpha joining 20","termid":"PBO:0078030"}


id: GO:0005604
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.","definition_xrefs":["PMID:22505934","PMID:33605520","PMID:39223427"],"direct_ancestors":[{"relation_name":"is_a","term_name":"extracellular matrix","termid":"GO:0031012"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"basement membrane","secondary_identifiers":["GO:0008003","GO:0005605","Wikipedia:Basement_membrane"],"synonyms":[{"name":"basal lamina","type":"related"},{"name":"basement lamina","type":"related"},{"name":"lamina densa","type":"related"}],"termid":"GO:0005604"}


id: PR:O13863
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC1B1.02c gene.","definition_xrefs":["PRO:DNx","UniProtKB:O13863"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized kinase C1B1.02c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1B1.02c","synonyms":[{"name":"Spom972h-SPAC1B1.02c","type":"exact"}],"termid":"PR:O13863"}


id: FYPO:0000906
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrion inheritance is abnormal. Mitochondrion inheritance is a cellular process that results in the distribution of mitochondria into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton.","definition_xrefs":["PomBase:mah","GO:0000001"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal mitochondrial distribution","termid":"FYPO:0000489"},{"relation_name":"is_a","term_name":"abnormal cellular component organization during vegetative growth","termid":"FYPO:0001353"},{"relation_name":"is_a","term_name":"abnormal mitochondrion inheritance","termid":"FYPO:0007274"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000002","FYPO:0001320","FYPO:0001985","FYPO:0000138"],"is_obsolete":false,"name":"abnormal mitochondrion inheritance during vegetative growth","synonyms":[{"name":"abnormal mitochondrial inheritance during vegetative growth","type":"exact"},{"name":"abnormal mitochondrion inheritance during mitotic cell cycle","type":"related"}],"termid":"FYPO:0000906"}


id: PR:P87150
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPBC25H2.09 gene.","definition_xrefs":["PRO:DNx","UniProtKB:P87150"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MICOS complex subunit mic19 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC25H2.09","synonyms":[{"name":"Spom972h-SPBC25H2.09","type":"exact"}],"termid":"PR:P87150"}


id: MONDO:0014279
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete arrhythmogenic right ventricular dysplasia, familial, 13 (obsolete MONDO:0014279)","termid":"MONDO:0014279","xrefs":{"Monarch":{"xref_id":"0014279"}}}


id: MONDO:0001356
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Anemia caused by low iron intake, inefficient iron absorption in the gastrointestinal tract, or chronic blood loss.","definition_xrefs":["NCIT:C84484"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hypochromic microcytic anemia","termid":"MONDO:0000387"},{"relation_name":"is_a","term_name":"nutritional deficiency disease","termid":"MONDO:0006873"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0002280"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0002280"],"is_obsolete":false,"name":"iron deficiency anemia","secondary_identifiers":["ICD9:280.9","DOID:11758","ICD9:280.8","MEDGEN:57668","MESH:D018798","SCTID:87522002","UMLS:C0162316"],"synonyms":[{"name":"iron-deficiency anaemia","type":"exact"},{"name":"iron-deficiency anemia","type":"exact"}],"termid":"MONDO:0001356","xrefs":{"Monarch":{"xref_id":"0001356"}}}


id: GO:0042048
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The behavior of an organism in response to an odor.","definition_xrefs":["GOC:jid","GOC:pr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chemosensory behavior","termid":"GO:0007635"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"olfactory behavior","synonyms":[{"name":"behavioral response to scent","type":"exact"},{"name":"behavioral response to smell","type":"exact"},{"name":"behavioural response to odour","type":"exact"},{"name":"behavioural response to scent","type":"exact"},{"name":"behavioural response to smell","type":"exact"},{"name":"olfactory behaviour","type":"exact"}],"termid":"GO:0042048"}


id: PBO:0064621
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"POU6F2 antisense RNA 1","termid":"PBO:0064621"}


id: PBO:0051676
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"inhibitor of growth family, X-linked (pseudogene)","termid":"PBO:0051676"}


id: PATO:0001254
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A color consisting of magenta with low brightness.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"magenta","termid":"PATO:0000321"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dark magenta","termid":"PATO:0001254"}


id: MONDO:0015971
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete rare genetic adrenal disease (obsolete MONDO:0015971)","secondary_identifiers":["Orphanet:183637"],"termid":"MONDO:0015971","xrefs":{"Monarch":{"xref_id":"0015971"}}}


id: GO:0099154
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A synapse that uses serotonin as a neurotransmitter.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"synapse","termid":"GO:0045202"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"serotonergic synapse","termid":"GO:0099154"}


id: GO:0045567
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 2.","definition_xrefs":["GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of TRAIL receptor 2 biosynthetic process (obsolete GO:0045567)","synonyms":[{"name":"down regulation of TRAIL receptor 2 biosynthetic process","type":"exact"},{"name":"down-regulation of TRAIL receptor 2 biosynthetic process","type":"exact"},{"name":"downregulation of TRAIL receptor 2 biosynthetic process","type":"exact"},{"name":"inhibition of TRAIL receptor 2 biosynthetic process","type":"narrow"},{"name":"negative regulation of TRAIL receptor 2 anabolism","type":"exact"},{"name":"negative regulation of TRAIL receptor 2 biosynthesis","type":"exact"},{"name":"negative regulation of TRAIL receptor 2 formation","type":"exact"},{"name":"negative regulation of TRAIL receptor 2 synthesis","type":"exact"}],"termid":"GO:0045567"}


id: PBO:0048810
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"G protein subunit beta 4","termid":"PBO:0048810"}


id: MONDO:0032739
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"spermatogenic failure","termid":"MONDO:0004983"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005047"}],"interesting_parent_ids":["MONDO:0005047"],"is_obsolete":false,"name":"spermatogenic failure 36","secondary_identifiers":["OMIM:618420","MEDGEN:1678385","UMLS:C5193086","DOID:0111921"],"synonyms":[{"name":"SPERMATOGENIC FAILURE 36","type":"related"},{"name":"SPGF36","type":"related"}],"termid":"MONDO:0032739","xrefs":{"Monarch":{"xref_id":"0032739"}}}


id: GO:0060088
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of auditory hair cells.","definition_xrefs":["PMID:10978835","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inner ear receptor cell stereocilium organization","termid":"GO:0060122"},{"relation_name":"part_of","term_name":"auditory receptor cell morphogenesis","termid":"GO:0002093"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"auditory receptor cell stereocilium organization","synonyms":[{"name":"auditory receptor cell stereocilium organisation","type":"exact"},{"name":"auditory receptor cell stereocilium organization and biogenesis","type":"related"}],"termid":"GO:0060088"}


id: MONDO:0001839
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete interstitial cystitis (obsolete MONDO:0001839)","termid":"MONDO:0001839","xrefs":{"Monarch":{"xref_id":"0001839"}}}


id: FYPO:0002369
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 56 of histone H3 in centromere outer repeat regions occurs to a greater extent than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased H3-K56 acetylation during vegetative growth","termid":"FYPO:0008270"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0002494"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001985","FYPO:0002274","FYPO:0001320","FYPO:0002494","FYPO:0000002"],"is_obsolete":false,"name":"increased histone H3-K56 acetylation at centromere outer repeat during vegetative growth","synonyms":[{"name":"abnormal histone H3-K56 acetylation at centromere otr during vegetative growth","type":"exact"},{"name":"abnormal histone H3-K56 acetylation at centromeric outer repeat region during vegetative growth","type":"exact"},{"name":"abnormal histone H3-K56 acetylation at pericentric region during vegetative growth","type":"related"},{"name":"abnormal histone H3-K56 acetylation at pericentromeric region during vegetative growth","type":"related"},{"name":"increased histone H3-K56 acetylation at centromere outer repeat during mitotic cell cycle","type":"related"},{"name":"increased histone H3K56 acetylation at centromere outer repeat during vegetative growth","type":"exact"}],"termid":"FYPO:0002369"}


id: PATO:0000186
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"An organismal quality inhering in a bearer by virtue of the bearer's behavior aggregate of the responses or reactions or movements in a given situation.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"organismal quality","termid":"PATO:0001995"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"behavioral quality","secondary_identifiers":["PATO:0001722"],"synonyms":[{"name":"behavioural quality","type":"exact"}],"termid":"PATO:0000186"}


id: PR:Q9US04
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A gamma-glutamyltranspeptidase 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO00702","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"gamma-glutamyltranspeptidase 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC664.09","secondary_identifiers":["UniProtKB:Q9US04"],"synonyms":[{"name":"Spom972h-GGT1","type":"exact"},{"name":"gamma-glutamyltransferase 1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"glutathione hydrolase 1 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9US04"}


id: PBO:0082862
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Core Sm protein Sm D1; part of heteroheptameric complex (with Smb1p, Smd2p, Smd3p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; relocalizes to the cytosol in response to hypoxia; homolog of human Sm D1; protein abundance increases in response to DNA replication stress","termid":"PBO:0082862"}


id: GO:0072731
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a papulacandin B stimulus.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to lipid","termid":"GO:0071396"},{"relation_name":"is_a","term_name":"response to papulacandin B","termid":"GO:0072730"},{"relation_name":"is_a","term_name":"cellular response to oxygen-containing compound","termid":"GO:1901701"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to papulacandin B","termid":"GO:0072731"}


id: PBO:0027107
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_protein_localization_to_nucleus,_with_protein_mislocalized_to_cytoplasmic_foci","termid":"PBO:0027107"}


id: PBO:0039987
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ADP ribosylation factor like GTPase 6 interacting protein 1 pseudogene 1","termid":"PBO:0039987"}


id: GO:0051503
data:
  {"annotated_genes":["SJAG_02050","SJAG_03334","SJAG_00612","SJAG_04328"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[76478],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015866"},{"annotations":[103291],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990554"},{"annotations":[103292],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990553"},{"annotations":[59113],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140021"},{"annotations":[59112,104790],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990544"},{"annotations":[94787],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990549"}]},"cv_name":"biological_process","definition":"The directed movement of adenine nucleotides, ATP, ADP, and/or AMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"purine nucleotide transport","termid":"GO:0015865"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00612":null,"SJAG_02050":null,"SJAG_03334":null,"SJAG_04328":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0051179","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"adenine nucleotide transport","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0051503","terms_by_termid":{"GO:0015866":null,"GO:0140021":null,"GO:1990544":null,"GO:1990549":null,"GO:1990553":null,"GO:1990554":null}}


id: MONDO:0013037
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Giacheti syndrome","secondary_identifiers":["UMLS:C2752043","OMIM:612917","MEDGEN:414543","MESH:C567864"],"synonyms":[{"name":"Giacheti syndrome","type":"exact"},{"name":"Marfanoid habitus and specific language and learning disabilities","type":"related"}],"termid":"MONDO:0013037","xrefs":{"Monarch":{"xref_id":"0013037"}}}


id: FYPO:0001231
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype in which the size, shape, and structure of the cell cortex is normal (i.e. indistinguishable from wild type). The cell cortex is the region of a cell that lies just beneath the plasma membrane.","definition_xrefs":["GO:0005938","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal subcellular component","termid":"FYPO:0001233"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0000002"],"is_obsolete":false,"name":"normal cell cortex morphology","termid":"FYPO:0001231"}


id: GO:0034077
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.","definition_xrefs":["ISBN:0911910123"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glycol metabolic process","termid":"GO:0042844"},{"relation_name":"is_a","term_name":"secondary alcohol metabolic process","termid":"GO:1902652"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0044281"],"is_obsolete":false,"name":"butanediol metabolic process","synonyms":[{"name":"butanediol metabolism","type":"exact"},{"name":"butylene glycol metabolic process","type":"exact"},{"name":"butylene glycol metabolism","type":"exact"}],"termid":"GO:0034077"}


id: PBO:0058109
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4324","termid":"PBO:0058109"}


id: GO:0020025
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"Singlet microtubule that lie underneath the inner membrane pellicle complex and emanate from the basal ring of the conoid.","definition_xrefs":["PMID:24800253","GOC:mb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"microtubule","termid":"GO:0005874"},{"relation_name":"part_of","term_name":"apical complex","termid":"GO:0020007"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0015630"}],"interesting_parent_ids":["GO:0015630","GO:0005575"],"is_obsolete":false,"name":"subpellicular microtubule","termid":"GO:0020025"}


id: PBO:0051379
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin kappa variable 6-21 (non-functional)","termid":"PBO:0051379"}


id: PBO:0090361
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin-protein ligase E3, unknown specificity","termid":"PBO:0090361"}


id: MONDO:0014231
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any Parkinson disease in which the cause of the disease is a mutation in the DNAJC6 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"juvenile-onset Parkinson disease","termid":"MONDO:0000828"},{"relation_name":"is_a","term_name":"atypical juvenile parkinsonism","termid":"MONDO:0018321"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"juvenile onset Parkinson disease 19A","secondary_identifiers":["DOID:0060891","MEDGEN:816141","UMLS:C3809811","GARD:18461","OMIM:615528"],"synonyms":[{"name":"DNAJC6 Parkinson disease","type":"exact"},{"name":"PARK19","type":"related"},{"name":"PARK19A","type":"related"},{"name":"Park19, formerly","type":"related"},{"name":"Parkinson disease 19, juvenile-onset","type":"related"},{"name":"Parkinson disease 19A, juvenile-onset","type":"related"},{"name":"Parkinson disease 19B, early-onset","type":"related"},{"name":"Parkinson disease caused by mutation in DNAJC6","type":"exact"},{"name":"juvenile onset Parkinson disease 19A","type":"exact"},{"name":"juvenile onset Parkinson disease type 19A","type":"exact"},{"name":"juvenile onset Parkinson's disease 19A","type":"related"}],"termid":"MONDO:0014231","xrefs":{"Monarch":{"xref_id":"0014231"}}}


id: GO:0035819
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"An increase in the amount of sodium excreted in urine over a unit of time, as a result of pressure natriuresis.","definition_xrefs":["GOC:mtg_25march11","GOC:yaf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pressure natriuresis","termid":"GO:0003095"},{"relation_name":"is_a","term_name":"positive regulation of renal sodium excretion","termid":"GO:0035815"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810"],"is_obsolete":false,"name":"positive regulation of renal sodium excretion by pressure natriuresis","synonyms":[{"name":"natriuresis resulting from pressure natriuresis","type":"related"}],"termid":"GO:0035819"}


id: PBO:0009146
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"calcium-dependent serine/threonine protein phosphatase calcineurin A, catalytic subunit Ppb1","termid":"PBO:0009146"}


id: PBO:0002183
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Muskelin homolog (predicted)","termid":"PBO:0002183"}


id: PBO:0088683
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ESCRT 0 complex subunit, sorting receptor for ubiquitinated membrane proteins, Hse1","termid":"PBO:0088683"}


id: PBO:0087371
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Spt4p/5p (DSIF) transcription elongation factor complex subunit; the Spt4/5 complex binds to ssRNA in a sequence-specific manner, and in concert with RNAP I and II has multiple roles regulating transcriptional elongation, RNA processing, quality control, and transcription-coupled repair; interacts with DNA upstream of RNAPII and the non-template strand of the transcription bubble; Spt5p is the only transcription elongation factor conserved in all domains of life","termid":"PBO:0087371"}


id: MONDO:0003218
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A lesion in which the normally situated glands are partially or completely replaced by atypical cells with malignant characteristics.","definition_xrefs":["NCIT:C4123"],"direct_ancestors":[{"relation_name":"is_a","term_name":"in situ carcinoma","termid":"MONDO:0004647"},{"relation_name":"is_a","term_name":"adenocarcinoma","termid":"MONDO:0004970"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"adenocarcinoma in situ","secondary_identifiers":["ICDO:8140/2","ONCOTREE:AIS","DOID:4943","UMLS:C0334276","MEDGEN:87203","MESH:D065311"],"synonyms":[{"name":"AIS","type":"related"},{"name":"adenocarcinoma in situ","type":"exact"}],"termid":"MONDO:0003218","xrefs":{"Monarch":{"xref_id":"0003218"}}}


id: MONDO:0001540
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An occupational lung disorder caused by inhalation of bagasse dust. In the acute phase, it manifests as cough, dyspnea, fever, chills, and weakness. Chronic exposure may lead to interstitial lung fibrosis.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hypersensitivity pneumonitis","termid":"MONDO:0017853"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"bagassosis","secondary_identifiers":["ICD9:495.1","MEDGEN:2539","ICD10CM:J67.1","icd11.foundation:1123061945","NCIT:C34409","MESH:D011009","SCTID:67242002","UMLS:C0004681","DOID:12522"],"synonyms":[{"name":"bagasse extrinsic allergic alveolitis","type":"exact"},{"name":"bagasse workers lung","type":"exact"},{"name":"extrinsic allergic alveolitis from bagasse","type":"exact"},{"name":"sugar cane worker pneumonitis","type":"exact"}],"termid":"MONDO:0001540","xrefs":{"Monarch":{"xref_id":"0001540"}}}


id: GO:0036483
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.","definition_xrefs":["GOC:bf","PMID:21113145","GOC:PARL"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress","termid":"GO:0070059"},{"relation_name":"part_of","term_name":"neuron apoptotic process","termid":"GO:0051402"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress","synonyms":[{"name":"ER stress-induced neuron apoptosis","type":"broad"},{"name":"ER stress-induced neuron intrinsic apoptotic signaling pathway","type":"exact"},{"name":"endoplasmic reticulum stress-induced neuron apoptosis","type":"broad"},{"name":"endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway","type":"exact"}],"termid":"GO:0036483"}


id: MONDO:0002557
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete schwannomatosis (obsolete MONDO:0002557)","termid":"MONDO:0002557","xrefs":{"Monarch":{"xref_id":"0002557"}}}


id: GO:0097188
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which calcium salts are deposited into the calcareous tooth structure known as dentin.","definition_xrefs":["GOC:sl","PMID:21196346","PMID:10206335"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tooth mineralization","termid":"GO:0034505"},{"relation_name":"part_of","term_name":"dentinogenesis","termid":"GO:0097187"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"dentin mineralization","synonyms":[{"name":"dentine mineralization","type":"exact"}],"termid":"GO:0097188"}


id: MONDO:0012976
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any autosomal dominant nonsyndromic deafness in which the cause of the disease is a mutation in the GJB3 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant nonsyndromic hearing loss","termid":"MONDO:0019587"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0019497"}],"interesting_parent_ids":["MONDO:0000426","MONDO:0019497"],"is_obsolete":false,"name":"autosomal dominant nonsyndromic hearing loss 2B","secondary_identifiers":["GARD:18131","MESH:C567214","OMIM:612644","DOID:0110559","UMLS:C2675236","MEDGEN:390742"],"synonyms":[{"name":"DFNA2B","type":"narrow"},{"name":"GJB3 autosomal dominant nonsyndromic deafness","type":"narrow"},{"name":"autosomal dominant deafness 2B","type":"narrow"},{"name":"autosomal dominant nonsyndromic deafness 2B","type":"narrow"},{"name":"autosomal dominant nonsyndromic deafness caused by mutation in GJB3","type":"narrow"},{"name":"autosomal dominant nonsyndromic deafness type 2B","type":"narrow"},{"name":"deafness, autosomal dominant 2B","type":"narrow"},{"name":"deafness, autosomal dominant 2b","type":"narrow"},{"name":"deafness, autosomal dominant type 2B","type":"narrow"}],"termid":"MONDO:0012976","xrefs":{"Monarch":{"xref_id":"0012976"}}}


id: MONDO:0016648
data:
  {"annotated_genes":["SJAG_02463","SJAG_01941"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87575,87576],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009189"}]},"cv_name":"mondo","definition":"Multiple epiphyseal dysplasias (MED/EDMs) are characterized by epiphyseal anomalies causing joint pain early in life, recurrent osteochondritis and early arthrosis. The EDMs are a heterogeneous group of diseases with variable expression classed as MED/EDMs 1-6.","definition_xrefs":["Orphanet:251"],"direct_ancestors":[{"relation_name":"is_a","term_name":"osteochondrodysplasia","termid":"MONDO:0005516"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01941":null,"SJAG_02463":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"multiple epiphyseal dysplasia","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["SCTID:59708000","ICD10CM:Q77.3","icd11.foundation:2009123831","ICD9:756.56","DOID:12721","GARD:10756","MEDGEN:6461","HP:0002654","NORD:1468","OMIMPS:132400","UMLS:C0026760","MedDRA:10028197"],"synonyms":[{"name":"Dominant Multiple Epiphyseal Dysplasia","type":"exact"},{"name":"EDM","type":"exact"},{"name":"MED","type":"exact"},{"name":"Polyepiphyseal dysplasia","type":"exact"},{"name":"epiphyseal dysplasia, multiple","type":"related"},{"name":"multiple epiphyseal dysplasia","type":"exact"},{"name":"multiple epiphyseal dysplasia (disease)","type":"exact"},{"name":"polyepiphyseal dysplasia","type":"exact"}],"termid":"MONDO:0016648","terms_by_termid":{"MONDO:0009189":null},"xrefs":{"Monarch":{"xref_id":"0016648"}}}


id: GO:0052582
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (R)-pulegone + reduced [NADPH--hemoprotein reductase] + O2 = (R)-menthofuran + 2 H2O + +H+ + oxidized [NADPH--hemoprotein reductase].","definition_xrefs":["RHEA:25658"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen","termid":"GO:0016712"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"(+)-menthofuran synthase activity","secondary_identifiers":["MetaCyc:1.14.13.104-RXN","EC:1.14.14.143","KEGG_REACTION:R08923"],"synonyms":[{"name":"(+)-MFS activity","type":"broad"},{"name":"(+)-pulegone 9-hydroxylase activity","type":"related"},{"name":"(+)-pulegone,NADPH:oxygen oxidoreductase (9-hydroxylating) activity","type":"related"},{"name":"cytochrome P450 menthofuran synthase activity","type":"related"},{"name":"menthofuran synthase activity","type":"related"}],"termid":"GO:0052582"}


id: GO:1904561
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenidol stimulus.","definition_xrefs":["PMID:25796330","GO_REF:0000071","GOC:mr","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to alcohol","termid":"GO:0097306"},{"relation_name":"is_a","term_name":"cellular response to nitrogen compound","termid":"GO:1901699"},{"relation_name":"is_a","term_name":"response to diphenidol","termid":"GO:1904560"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to diphenidol","termid":"GO:1904561"}


id: SO:0002352
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A non-coding RNA typically derived from intronic sequence of the sense strand of a cognate host gene, that is not rapidly degraded. It may contain exonic sequences, 5′ caps, and/or polyA tails.","definition_xrefs":["PMID:30391089","PMID:29397203","PMID:27147469"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ncRNA","termid":"SO:0000655"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sisRNA","synonyms":[{"name":"Stable intronic sequence RNA","type":"exact"},{"name":"stable_intronic_sequence_RNA","type":"exact"}],"termid":"SO:0002352"}


id: GO:0099646
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Vesicle-mediated transport of a neurotransmitter receptor vesicle from the plasma membrane to the endosome.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein localization to endosome","termid":"GO:0036010"},{"relation_name":"is_a","term_name":"plasma membrane to endosome transport","termid":"GO:0048227"},{"relation_name":"is_a","term_name":"establishment of protein localization to organelle","termid":"GO:0072594"},{"relation_name":"is_a","term_name":"neurotransmitter receptor transport","termid":"GO:0099637"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0016192"}],"interesting_parent_ids":["GO:0051179","GO:0016192","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"neurotransmitter receptor transport, plasma membrane to endosome","termid":"GO:0099646"}


id: MONDO:0017570
data:
  {"annotated_genes":["SJAG_01960"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87439],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009953"}]},"cv_name":"mondo","definition":"Leukocyte adhesion deficiency (LAD) is a primary immunodeficiency characterized by defects in the leukocyte adhesion process, marked leukocytosis and recurrent infections.","definition_xrefs":["Orphanet:2968"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive disease","termid":"MONDO:0006025"},{"relation_name":"is_a","term_name":"functional neutrophil defect","termid":"MONDO:0015978"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01960":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0005046","MONDO:0006025"],"is_obsolete":false,"name":"leukocyte adhesion deficiency","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:16616","MEDGEN:124419","NANDO:2200755","DOID:6612","UMLS:C0272187","icd11.foundation:317341989","NANDO:1200355","NCIT:C27874","SCTID:77358003"],"synonyms":[{"name":"LAD","type":"broad"},{"name":"congenital leukocyte adherence deficiency","type":"exact"}],"termid":"MONDO:0017570","terms_by_termid":{"MONDO:0009953":null},"xrefs":{"Monarch":{"xref_id":"0017570"}}}


id: GO:0071600
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of the otic vesicle are generated and organized. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inner ear morphogenesis","termid":"GO:0042472"},{"relation_name":"is_a","term_name":"embryonic organ morphogenesis","termid":"GO:0048562"},{"relation_name":"is_a","term_name":"epithelial tube morphogenesis","termid":"GO:0060562"},{"relation_name":"part_of","term_name":"otic vesicle development","termid":"GO:0071599"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"otic vesicle morphogenesis","termid":"GO:0071600"}


id: MONDO:0012033
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Bradyopsia is characterized by prolonged electroretinal response suppression leading to difficulties adjusting to changes in luminance, normal to subnormal acuity and photophobia.","definition_xrefs":["Orphanet:75374"],"direct_ancestors":[{"relation_name":"is_a","term_name":"retinal disorder","termid":"MONDO:0005283"},{"relation_name":"is_a","term_name":"hereditary neurological disease","termid":"MONDO:0100545"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"bradyopsia","secondary_identifiers":["ICD9:368.8","DOID:0050335","icd11.foundation:1497247503","UMLS:C1842073","GARD:12299","MEDGEN:331206","MESH:C564243","SCTID:711163009","OMIMPS:608415"],"synonyms":[{"name":"PERRS","type":"exact"},{"name":"bradyopsia","type":"exact"},{"name":"prolonged electroretinal response suppression","type":"exact"}],"termid":"MONDO:0012033","xrefs":{"Monarch":{"xref_id":"0012033"}}}


id: FYPO:0004715
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell contains fewer, but larger, vacuoles than normal when the cell is subject to salt stress.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"large vacuoles present in decreased numbers during vegetative growth","termid":"FYPO:0002795"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0001320","FYPO:0005447"],"is_obsolete":false,"name":"large vacuoles present in decreased numbers during salt stress","synonyms":[{"name":"enlarged vacuoles present in decreased numbers during salt stress","type":"exact"},{"name":"large vacuoles present in decreased numbers during salt stress during mitotic cell cycle","type":"related"},{"name":"large vacuoles present in decreased numbers during salt stress during vegetative growth","type":"exact"},{"name":"large vacuoles present in reduced numbers during salt stress","type":"exact"}],"termid":"FYPO:0004715"}


id: PBO:0003686
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial membrane protein Mgr2 (predicted)","termid":"PBO:0003686"}


id: PBO:0054560
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1962","termid":"PBO:0054560"}


id: GO:0036420
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The component of mycolate outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.","definition_xrefs":["GOC:md","GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"extrinsic component of cell outer membrane","termid":"GO:0031244"},{"relation_name":"part_of","term_name":"mycolate outer membrane","termid":"GO:0036407"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"extrinsic component of mycolate outer membrane","synonyms":[{"name":"extrinsic to MOM","type":"exact"},{"name":"extrinsic to mycolate outer membrane","type":"narrow"},{"name":"extrinsic to mycomembrane","type":"exact"}],"termid":"GO:0036420"}


id: MONDO:0020291
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hypoplastic right-heart syndrome (HRHS) is a rare, cyanotic congenital heart malformation caused by underdevelopment of the right-sided heart structures (tricuspid valve, RV, pulmonary valve, and pulmonary artery) commonly associated with an atrial septal defect, ostium secundum type. Pulmonary blood flow is diminished and right-to-left shunting occurs at the atrial level, leading to dyspnea, fatigue, atrial arrhythmias, right-sided heart failure, hypoxemia, repeated miscarriages that were mostly due to hypoxemia and cyanosis. Two subtypes of HRHS have been characterized: pulmonary atresia-intact ventricular septum and right ventricular hypoplasia.","definition_xrefs":["Orphanet:98723"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"univentricular cardiopathy","termid":"MONDO:0019820"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hypoplastic right heart syndrome","secondary_identifiers":["ICD10CM:Q22.6","MedDRA:10050053","NCIT:C99053","SCTID:268180007","DOID:0070315","GARD:2922","ICD9:746.89","MEDGEN:83376","UMLS:C0344963","MedDRA:10064962"],"synonyms":[{"name":"right hypoplastic heart syndrome","type":"exact"}],"termid":"MONDO:0020291","xrefs":{"Monarch":{"xref_id":"0020291"}}}


id: PBO:0080354
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vomeronasal 2 receptor 9, pseudogene","termid":"PBO:0080354"}


id: MONDO:0000869
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete congenital fibrosis of the extraocular muscles (obsolete MONDO:0000869)","termid":"MONDO:0000869","xrefs":{"Monarch":{"xref_id":"0000869"}}}


id: PBO:0003070
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcription factor TFIIF complex beta subunit Tfg2 (predicted)","termid":"PBO:0003070"}


id: GO:0050684
data:
  {"annotated_genes":["SJAG_03279","SJAG_01511","SJAG_04863","SJAG_01919","SJAG_04949","SJAG_02018","SJAG_00996","SJAG_01169","SJAG_01799","SJAG_02058","SJAG_03214","SJAG_04782","SJAG_01040","SJAG_05231"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[77905],"is_not":false,"summary":null,"term":"GO:0050684"},{"annotations":[120443,91346],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905746"},{"annotations":[77094,94041,75786,112909],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0048026"},{"annotations":[66145,113517,107438,115059,94773],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000381"},{"annotations":[100481],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905744"},{"annotations":[95627],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0048024"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of mRNA processing, those processes involved in the conversion of a primary mRNA transcript into a mature mRNA prior to its translation into polypeptide.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of mRNA metabolic process","termid":"GO:1903311"},{"relation_name":"regulates","term_name":"mRNA processing","termid":"GO:0006397"}],"gene_count":14,"genes_by_uniquename":{"SJAG_00996":null,"SJAG_01040":null,"SJAG_01169":null,"SJAG_01511":null,"SJAG_01799":null,"SJAG_01919":null,"SJAG_02018":null,"SJAG_02058":null,"SJAG_03214":null,"SJAG_03279":null,"SJAG_04782":null,"SJAG_04863":null,"SJAG_04949":null,"SJAG_05231":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0016071"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0016071","GO:0008150"],"is_obsolete":false,"name":"regulation of mRNA processing","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0050684","terms_by_termid":{"GO:0000381":null,"GO:0048024":null,"GO:0048026":null,"GO:0050684":null,"GO:1905744":null,"GO:1905746":null}}


id: MONDO:0015119
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete bronchopulmonary tumor (obsolete MONDO:0015119)","secondary_identifiers":["Orphanet:101945"],"synonyms":[{"name":"rare bronchopulmonary tumor","type":"exact"}],"termid":"MONDO:0015119","xrefs":{"Monarch":{"xref_id":"0015119"}}}


id: GO:0031764
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a type 1 galanin receptor.","definition_xrefs":["GOC:nln","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"galanin receptor binding","termid":"GO:0031763"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0005515","GO:0005488","GO:0003674"],"is_obsolete":false,"name":"type 1 galanin receptor binding","synonyms":[{"name":"type 1 galanin receptor ligand","type":"narrow"}],"termid":"GO:0031764"}


id: PBO:0091485
data:
  {"annotation_feature_type":"gene","cv_name":"misc","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long tco1 transcript produced under low-oxygen conditions is not translated","termid":"PBO:0091485"}


id: FYPO:0005595
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a ceramide measured in a cell is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal level of substance in cell during vegetative growth","termid":"FYPO:0001316"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000002","FYPO:0000257","FYPO:0001312"],"is_obsolete":false,"name":"normal cellular ceramide level","synonyms":[{"name":"normal cellular ceramide accumulation","type":"related"},{"name":"normal cellular ceramide level during mitotic cell cycle","type":"related"},{"name":"normal cellular ceramide level during vegetative growth","type":"exact"}],"termid":"FYPO:0005595"}


id: GO:0050829
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"defense response to bacterium","termid":"GO:0042742"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"defense response to Gram-negative bacterium","synonyms":[{"name":"Gram-negative antibacterial peptide activity","type":"related"},{"name":"defence response to Gram-negative bacteria","type":"exact"},{"name":"defence response to Gram-negative bacterium","type":"exact"},{"name":"defense response to Gram-negative bacteria","type":"exact"}],"termid":"GO:0050829"}


id: MONDO:0013087
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any bronchiectasis in which the cause of the disease is a mutation in the SCNN1A gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"idiopathic bronchiectasis","termid":"MONDO:0018956"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bronchiectasis with or without elevated sweat chloride 2","secondary_identifiers":["MEDGEN:414437","UMLS:C2751666","MESH:C567813","GARD:18055","OMIM:613021","DOID:0080527"],"synonyms":[{"name":"BESC2","type":"related"},{"name":"SCNN1A bronchiectasis","type":"exact"},{"name":"bronchiectasis caused by mutation in SCNN1A","type":"exact"},{"name":"bronchiectasis with or without elevated sweat chloride 2","type":"exact"},{"name":"bronchiectasis with or without elevated sweat chloride type 2","type":"exact"},{"name":"cystic fibrosis-like syndrome","type":"related"}],"termid":"MONDO:0013087","xrefs":{"Monarch":{"xref_id":"0013087"}}}


id: MONDO:0002047
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"systemic sclerosis","termid":"MONDO:0005100"},{"relation_name":"is_a","term_name":"lung disorder","termid":"MONDO:0005275"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005093"],"is_obsolete":false,"name":"pulmonary systemic sclerosis","secondary_identifiers":["UMLS:C0339904","SCTID:196133001","ICD9:517.2","DOID:1578","MEDGEN:573414"],"synonyms":[{"name":"lung disease with systemic sclerosis","type":"exact"},{"name":"lung involvement in systemic sclerosis","type":"exact"},{"name":"scleroderma lung disease","type":"exact"},{"name":"scleroderma of lung","type":"related"}],"termid":"MONDO:0002047","xrefs":{"Monarch":{"xref_id":"0002047"}}}


id: GO:0002302
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which an antigenically naive CD8-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.","definition_xrefs":["ISBN:0781735149","GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"alpha-beta T cell differentiation involved in immune response","termid":"GO:0002293"},{"relation_name":"is_a","term_name":"CD8-positive, alpha-beta T cell differentiation","termid":"GO:0043374"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"CD8-positive, alpha-beta T cell differentiation involved in immune response","synonyms":[{"name":"CD8-positive, alpha-beta T cell differentiation during immune response","type":"related"},{"name":"CD8-positive, alpha-beta T lymphocyte differentiation during immune response","type":"related"},{"name":"CD8-positive, alpha-beta T-cell differentiation during immune response","type":"related"},{"name":"CD8-positive, alpha-beta T-lymphocyte differentiation during immune response","type":"related"},{"name":"CD8-positive, alpha-beta intraepithelial T cell development","type":"related"}],"termid":"GO:0002302"}


id: PBO:0066515
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"regulator of cell cycle","termid":"PBO:0066515"}


id: MONDO:0958329
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Mendelian neurodevelopmental disorder","termid":"MONDO:0100500"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0700092"}],"interesting_parent_ids":["MONDO:0700092"],"is_obsolete":false,"name":"Jeffries-Lakhani neurodevelopmental syndrome","secondary_identifiers":["UMLS:C5935596","MEDGEN:1854360","OMIM:620771"],"termid":"MONDO:0958329","xrefs":{"Monarch":{"xref_id":"0958329"}}}


id: MONDO:0044937
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A malignant epithelial neoplasm that arises from the rectum and invades through the muscularis mucosa into the submucosa. The vast majority are adenocarcinomas.","definition_xrefs":["NCIT:C9382"],"direct_ancestors":[{"relation_name":"is_a","term_name":"rectal cancer","termid":"MONDO:0006519"},{"relation_name":"is_a","term_name":"colorectal carcinoma","termid":"MONDO:0024331"},{"relation_name":"is_a","term_name":"epithelial neoplasm of rectum","termid":"MONDO:0024476"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0004992"],"is_obsolete":false,"name":"rectal carcinoma","secondary_identifiers":["MEDGEN:40100","UMLS:C0007113"],"synonyms":[{"name":"cancer of rectum","type":"broad"},{"name":"cancer of the rectum","type":"broad"},{"name":"carcinoma of rectum","type":"exact"},{"name":"carcinoma of the rectum","type":"exact"},{"name":"rectal cancer","type":"broad"},{"name":"rectal carcinoma","type":"exact"},{"name":"rectum carcinoma","type":"exact"}],"termid":"MONDO:0044937","xrefs":{"Monarch":{"xref_id":"0044937"}}}


id: MONDO:0009735
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Netherton syndrome (NS) is a skin disorder characterized by congenital ichthyosiform erythroderma (CIE), a distinctive hair shaft defect (trichorrhexis invaginata; TI) and atopic manifestations.","definition_xrefs":["Orphanet:634"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete eyebrow/eyelashes structural anomaly (obsolete MONDO:0020189)","termid":"MONDO:0020189"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"eye disorder","termid":"MONDO:0005328"},{"relation_name":"is_a","term_name":"autosomal recessive disease","termid":"MONDO:0006025"},{"relation_name":"is_a","term_name":"inherited ichthyosis","termid":"MONDO:0015947"},{"relation_name":"is_a","term_name":"hyper-IgE syndrome","termid":"MONDO:0018037"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"},{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0006025","MONDO:0005093","MONDO:0005328","MONDO:0005046"],"is_obsolete":false,"name":"Netherton syndrome","secondary_identifiers":["NANDO:1200338","NCIT:C84922","MedDRA:10062909","OMIM:256500","MEDGEN:1802991","SCTID:54336006","NORD:1290","icd11.foundation:1797493665","GARD:7182","MESH:D056770","UMLS:C5574950","SCTID:312514006","DOID:0050474","NANDO:1200619","NANDO:2200993"],"synonyms":[{"name":"Comel-Netherton syndrome","type":"related"},{"name":"Comèl-Netherton syndrome","type":"exact"},{"name":"Ichthyosis, Netherton Syndrome","type":"exact"},{"name":"NS","type":"exact"},{"name":"Netherton disease","type":"related"},{"name":"Netherton syndrome","type":"exact"},{"name":"bamboo hair syndrome","type":"exact"},{"name":"erythroderma, ichthyosiform, with hypotrichosis and hyper-IgE","type":"related"},{"name":"neth","type":"related"}],"termid":"MONDO:0009735","xrefs":{"Monarch":{"xref_id":"0009735"}}}


id: PBO:0038361
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-parasitoid_of","termid":"PBO:0038361"}


id: PBO:0088602
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"7,8-diamino-pelargonic acid aminotransferase (DAPA)","termid":"PBO:0088602"}


id: PBO:0053682
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 869","termid":"PBO:0053682"}


id: GO:0043632
data:
  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id: PBO:0030283
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id: GO:0110152
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id: PBO:0003258
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id: PBO:0042771
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id: PR:Q10110
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id: PBO:0113113
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id: GO:0032830
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id: PBO:0062423
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id: GO:0008940
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id: PBO:0029078
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  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-third_meiotic_division","termid":"PBO:0029078"}


id: GO:0005132
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id: PBO:0005647
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id: GO:0047722
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  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 3-(indol-3-yl)lactate + NAD+ = 3-(indol-3-yl)pyruvate + H+ + NADH.","definition_xrefs":["RHEA:20133"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016491","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"indolelactate dehydrogenase (NAD+) activity","secondary_identifiers":["MetaCyc:INDOLELACTATE-DEHYDROGENASE-RXN","KEGG_REACTION:R01971"],"synonyms":[{"name":"(indol-3-yl)lactate:NAD+ oxidoreductase activity","type":"related"},{"name":"indole-3-lactate dehydrogenase activity","type":"exact"},{"name":"indolelactate:NAD+ oxidoreductase activity","type":"related"}],"termid":"GO:0047722"}


id: PBO:0090981
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id: GO:0042889
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The directed movement of 3-phenylpropionic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.","definition_xrefs":["GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete 3-phenylpropionic acid transport (obsolete GO:0042889)","synonyms":[{"name":"3-phenylpropionate transport","type":"exact"},{"name":"HCA transport","type":"exact"},{"name":"hydrocinnamic acid transport","type":"exact"}],"termid":"GO:0042889"}


id: GO:0009261
data:
  {"annotated_genes":["SJAG_04192","SJAG_00839","SJAG_05314","SJAG_03676","SJAG_06622","SJAG_02369","SJAG_03828","SJAG_01310","SJAG_02945","SJAG_02107","SJAG_04870","SJAG_02481","SJAG_02785","SJAG_04495","SJAG_03660","SJAG_00605","SJAG_04048","SJAG_00027","SJAG_03903","SJAG_00461","SJAG_06621","SJAG_02135","SJAG_02009","SJAG_03373","SJAG_04334","SJAG_02796","SJAG_00685"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[81047],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1901911"},{"annotations":[118383],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006198"},{"annotations":[111366,99907,96420,118354,111368,111369,100178,105315,107774,111371,107775,107405,105573,79617,111370,111367,74194,111365,107403,107404],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061621"},{"annotations":[90469],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061613"},{"annotations":[74846,77912],"is_not":false,"rel_names":["negatively_regulates","regulates"],"summary":null,"term":"GO:0045820"},{"annotations":[71770],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0006110"},{"annotations":[78225],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006256"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.","definition_xrefs":["GOC:go_curators","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleotide catabolic process","termid":"GO:0009166"},{"relation_name":"is_a","term_name":"ribonucleotide metabolic process","termid":"GO:0009259"},{"relation_name":"is_a","term_name":"carbohydrate derivative catabolic process","termid":"GO:1901136"}],"gene_count":27,"genes_by_uniquename":{"SJAG_00027":null,"SJAG_00461":null,"SJAG_00605":null,"SJAG_00685":null,"SJAG_00839":null,"SJAG_01310":null,"SJAG_02009":null,"SJAG_02107":null,"SJAG_02135":null,"SJAG_02369":null,"SJAG_02481":null,"SJAG_02785":null,"SJAG_02796":null,"SJAG_02945":null,"SJAG_03373":null,"SJAG_03660":null,"SJAG_03676":null,"SJAG_03828":null,"SJAG_03903":null,"SJAG_04048":null,"SJAG_04192":null,"SJAG_04334":null,"SJAG_04495":null,"SJAG_04870":null,"SJAG_05314":null,"SJAG_06621":null,"SJAG_06622":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0055086","GO:0044281"],"is_obsolete":false,"name":"ribonucleotide catabolic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"ribonucleotide breakdown","type":"exact"},{"name":"ribonucleotide catabolism","type":"exact"},{"name":"ribonucleotide degradation","type":"exact"}],"termid":"GO:0009261","terms_by_termid":{"GO:0006110":null,"GO:0006198":null,"GO:0006256":null,"GO:0045820":null,"GO:0061613":null,"GO:0061621":null,"GO:1901911":null}}


id: MOD:01346
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-asparagine residue to an N4-hexosyl-L-asparagine.","definition_xrefs":["PubMed:6540775","Unimod:41#N","PubMed:11112526","PubMed:15279557","PubMed:11567090"],"direct_ancestors":[{"relation_name":"is_a","term_name":"N4-glycosyl-L-asparagine","termid":"MOD:00160"},{"relation_name":"is_a","term_name":"hexosylated residue","termid":"MOD:00434"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00764"}],"interesting_parent_ids":["MOD:00764"],"is_obsolete":false,"name":"N4-hexosylated asparagine","synonyms":[{"name":"Hex","type":"related"},{"name":"Hexose","type":"related"}],"termid":"MOD:01346"}


id: FYPO:0003149
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) in a mutant is decreased during a cellular response to methyl methanesulfonate. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased chromatin binding","termid":"FYPO:0002577"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000652","FYPO:0000707"],"is_obsolete":false,"name":"decreased chromatin binding during cellular response to methyl methanesulfonate","synonyms":[{"name":"decreased chromatin binding during cellular response to MMS","type":"exact"},{"name":"decreased chromatin binding during cellular response to methyl methanesulphonate","type":"exact"},{"name":"reduced chromatin binding during cellular response to methyl methanesulfonate","type":"exact"}],"termid":"FYPO:0003149"}


id: PBO:0040950
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BCL2 interacting protein 3 pseudogene 21","termid":"PBO:0040950"}


id: GO:0050967
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of events that contribute to the perception of pain in which an electrical stimulus is received and converted into a molecular signal.","definition_xrefs":["GOC:tb","GOC:ai","GOC:dos","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"detection of electrical stimulus involved in sensory perception","termid":"GO:0050963"},{"relation_name":"is_a","term_name":"detection of stimulus involved in sensory perception of pain","termid":"GO:0062149"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"detection of electrical stimulus involved in sensory perception of pain","synonyms":[{"name":"detection of electrical stimulus during sensory perception of pain","type":"related"},{"name":"perception of pain, detection of electrical stimulus","type":"exact"},{"name":"perception of pain, sensory detection of electrical stimulus","type":"exact"},{"name":"perception of pain, sensory transduction of electrical stimulus","type":"exact"},{"name":"sensory detection of electrical stimulus during perception of pain","type":"related"},{"name":"sensory transduction of electrical stimulus during perception of pain","type":"related"}],"termid":"GO:0050967"}


id: GO:1901678
data:
  {"annotated_genes":["SJAG_02457","SJAG_02834","SJAG_02735","SJAG_03667"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[91144],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140466"},{"annotations":[62566,62894,71068],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033214"}]},"cv_name":"biological_process","definition":"The directed movement of an iron coordination entity into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.","definition_xrefs":["GOC:TermGenie","GOC:pr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"iron ion transport","termid":"GO:0006826"}],"gene_count":4,"genes_by_uniquename":{"SJAG_02457":null,"SJAG_02735":null,"SJAG_02834":null,"SJAG_03667":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0008150","GO:0051179","GO:0006810"],"is_obsolete":false,"name":"iron coordination entity transport","references_by_uniquename":{"GO_REF:0000107":null,"GO_REF:0000108":null},"termid":"GO:1901678","terms_by_termid":{"GO:0033214":null,"GO:0140466":null}}


id: SO:1000138
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A compound chromosome whereby two copies of the same chromosomal arm attached to a common centromere. The chromosome is diploid for the arm involved.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"compound_chromosome","termid":"SO:1000042"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"homo_compound_chromosome","synonyms":[{"name":"homo compound chromosome","type":"exact"},{"name":"homo-compound chromosome","type":"exact"}],"termid":"SO:1000138"}


id: PBO:0067820
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 122","termid":"PBO:0067820"}


id: GO:0000295
data:
  {"annotated_genes":["SJAG_02050","SJAG_03334","SJAG_00612","SJAG_04328"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[103293],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0046964"},{"annotations":[103294],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1902557"},{"annotations":[59110],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005471"},{"annotations":[104791],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140987"},{"annotations":[77538],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051724"}]},"cv_name":"molecular_function","definition":"Enables the transfer of adenine nucleotides (AMP, ADP, and ATP) from one side of a membrane to the other.","definition_xrefs":["PMID:11566870"],"direct_ancestors":[{"relation_name":"is_a","term_name":"purine nucleotide transmembrane transporter activity","termid":"GO:0015216"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00612":null,"SJAG_02050":null,"SJAG_03334":null,"SJAG_04328":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0022857","GO:0005215"],"is_obsolete":false,"name":"adenine nucleotide transmembrane transporter activity","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-389652"],"termid":"GO:0000295","terms_by_termid":{"GO:0005471":null,"GO:0046964":null,"GO:0051724":null,"GO:0140987":null,"GO:1902557":null}}


id: PBO:0058823
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 8053","termid":"PBO:0058823"}


id: PBO:0090421
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ER membrane chaperone for multipass membrane proteins, PAT complex subunit, and TMCO1 translocon subunit (human CCDC47 ortholog)","termid":"PBO:0090421"}


id: PBO:0065557
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PTGES2 antisense RNA 1 (head to head)","termid":"PBO:0065557"}


id: PBO:0045683
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dynein light chain LC8-type 1 pseudogene 3","termid":"PBO:0045683"}


id: PBO:0054821
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2234","termid":"PBO:0054821"}


id: MOD:00772
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively substitutes a vanadium atom or a cluster containing vanadium for hydrogen atoms, or that coordinates a vanadium ion.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"metal or metal cluster containing modified residue","termid":"MOD:00698"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vanadium containing modified residue","synonyms":[{"name":"VRes","type":"exact"}],"termid":"MOD:00772"}


id: _global:interacts_with
data:
  {"annotation_feature_type":"gene","cv_name":"external","definition":"A relationship that holds between two entities in which the processes executed by the two entities are causally connected.","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"interacts_with","secondary_identifiers":["RO:0002434"],"synonyms":[{"name":"in pairwise interaction with","type":"exact"}],"termid":"_global:interacts_with"}


id: MONDO:0958233
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Bethlem myopathy","termid":"MONDO:0008029"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"},{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0002320","MONDO:0005336"],"is_obsolete":false,"name":"Bethlem myopathy 1B","secondary_identifiers":["OMIM:620725","MEDGEN:1859128","UMLS:C5935580"],"termid":"MONDO:0958233","xrefs":{"Monarch":{"xref_id":"0958233"}}}


id: GO:0004848
data:
  {"annotated_genes":["SJAG_05287"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[63093],"is_not":false,"summary":null,"term":"GO:0004848"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: (S)-ureidoglycolate + H2O + 2 H+ = CO2 + glyoxylate + 2 NH4.","definition_xrefs":["RHEA:19809"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides","termid":"GO:0016811"}],"gene_count":1,"genes_by_uniquename":{"SJAG_05287":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016810"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016810","GO:0016787"],"is_obsolete":false,"name":"ureidoglycolate hydrolase activity","references_by_uniquename":{"GO_REF:0000002":null},"secondary_identifiers":["EC:3.5.1.116","KEGG_REACTION:R00469","MetaCyc:UREIDOGLYCOLATE-HYDROLASE-RXN"],"synonyms":[{"name":"ureidoglycolate amidohydrolase activity","type":"exact"}],"termid":"GO:0004848","terms_by_termid":{"GO:0004848":null}}


id: PBO:0041473
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 11 open reading frame 52","termid":"PBO:0041473"}


id: PBO:0075649
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SPRY domain containing 4","termid":"PBO:0075649"}


id: PBO:0082147
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Acyl-CoA:sterol acyltransferase; endoplasmic reticulum enzyme that contributes the major sterol esterification activity in the presence of oxygen; ARE2 has a paralog, ARE1, that arose from the whole genome duplication","termid":"PBO:0082147"}


id: PBO:0072655
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"retrotransposon Gag like 8B","termid":"PBO:0072655"}


id: MONDO:0010311
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Becker muscular dystrophy (BMD) is a neuromuscular disease characterized by progressive muscle wasting and weakness due to degeneration of skeletal, smooth and cardiac muscle.","definition_xrefs":["Orphanet:98895"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DMD-related muscular dystrophy","termid":"MONDO:0700285"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0005336"],"is_obsolete":false,"name":"Becker muscular dystrophy","secondary_identifiers":["NCIT:C84587","OMIM:300376","DOID:9883","MEDGEN:182959","SCTID:387732009","NANDO:2200865","UMLS:C0917713","icd11.foundation:690532643","MedDRA:10059117","MESH:C570377","GARD:5900","NANDO:1200489"],"synonyms":[{"name":"BMD","type":"exact"},{"name":"Becker dystrophinopathy","type":"exact"},{"name":"Becker muscular dystrophy","type":"exact"},{"name":"Becker muscular dystrophy, X-linked recessive","type":"exact"},{"name":"Becker's muscular dystrophy","type":"related"},{"name":"benign congenital myopathy","type":"exact"},{"name":"benign pseudohypertrophic muscular dystrophy","type":"exact"},{"name":"muscular dystrophy pseudohypertrophic progressive, Becker type","type":"related"},{"name":"muscular dystrophy, Becker type","type":"related"},{"name":"muscular dystrophy, pseudohypertrophic progressive, Becker type","type":"related"}],"termid":"MONDO:0010311","xrefs":{"Monarch":{"xref_id":"0010311"}}}


id: PBO:0081363
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ZNF197 antisense RNA 1","termid":"PBO:0081363"}


id: GO:1990390
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is added to a protein.","definition_xrefs":["PMID:24768539"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein polyubiquitination","termid":"GO:0000209"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0070647"}],"interesting_parent_ids":["GO:0008150","GO:0070647"],"is_obsolete":false,"name":"protein K33-linked ubiquitination","termid":"GO:1990390"}


id: PBO:0071718
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L39 pseudogene 16","termid":"PBO:0071718"}


id: PBO:0061610
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NudC domain containing 1","termid":"PBO:0061610"}


id: PR:P40388
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- uvi15 gene.","definition_xrefs":["PRO:DNx","UniProtKB:P40388"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UV-induced protein uvi15 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC649.04","synonyms":[{"name":"Spom972h-uvi15","type":"exact"}],"termid":"PR:P40388"}


id: MONDO:0016991
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Acute necrotizing encephalopathy of childhood is a rare neurologic disease characterized by a rapid onset of seizures, an altered state of consciousness, neurologic decline, and variable degrees of hepatic dysfunction following a respiratory or gastrointesitnal infection (e.g. mycoplasma, influenza virus) in a previously healthy child. Brain MRI of patients reveals bilateral, multiple, symmetrical lesions predominantly observed in thalami and brainstem, but also in periventricular white matter and cerebellum in some cases.","definition_xrefs":["Orphanet:263524"],"direct_ancestors":[{"relation_name":"is_a","term_name":"infectious encephalitis","termid":"MONDO:0020067"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acute necrotizing encephalopathy of childhood","secondary_identifiers":["MEDGEN:1641610","GARD:17257","UMLS:C4706387","SCTID:763310000"],"synonyms":[{"name":"ANEC","type":"exact"},{"name":"isolated ANE","type":"exact"},{"name":"isolated acute necrotizing encephalopathy","type":"exact"}],"termid":"MONDO:0016991","xrefs":{"Monarch":{"xref_id":"0016991"}}}


id: PBO:0065331
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine protease 55","termid":"PBO:0065331"}


id: GO:0047382
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: S-methyl-3-phospho-1-thio-D-glycerate + H2O = S-methyl-1-thio-D-glycerate + phosphate.","definition_xrefs":["EC:3.1.3.14","RHEA:16081"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphatase activity","termid":"GO:0016791"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016788"}],"interesting_parent_ids":["GO:0016787","GO:0016788","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"methylphosphothioglycerate phosphatase activity","secondary_identifiers":["KEGG_REACTION:R04317","MetaCyc:3.1.3.14-RXN"],"synonyms":[{"name":"S-methyl-3-phospho-1-thio-D-glycerate phosphohydrolase activity","type":"related"},{"name":"methylthiophosphoglycerate phosphatase activity","type":"related"}],"termid":"GO:0047382"}


id: PR:Q9Y811
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- pth3 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9Y811"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized peptide chain release factor-like protein C1105.18c, mitochondrial (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC1105.18c","synonyms":[{"name":"Spom972h-pth3","type":"exact"}],"termid":"PR:Q9Y811"}


id: PBO:0045681
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dynein light chain LC8-type 1 pseudogene 1","termid":"PBO:0045681"}


id: PBO:0073758
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 2 member 12","termid":"PBO:0073758"}


id: PBO:0085089
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Nuclear envelope protein that acts as a recycling factor; mediates the nuclear export of Srp1p (importin alpha) back to the cytoplasm after its import substrates have been released into the nucleoplasm, thereby allowing the participation of Srp1p in multiple rounds of nuclear import; required for accurate chromosome segregation; homolog of metazoan CAS and human CSE1L, overexpression of which is implicated in cancer progression","termid":"PBO:0085089"}


id: FYPO:0005407
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which the occurrence of DNA recombination is increased in telomeric regions when the cell is subject to nitrogen starvation.","definition_xrefs":["PMID:12930956","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal DNA recombination","termid":"FYPO:0000063"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000293"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000293","FYPO:0000002","FYPO:0001985","FYPO:0005447"],"is_obsolete":false,"name":"increased DNA recombination at telomere during nitrogen starvation","synonyms":[{"name":"increased DNA recombination at telomere during nitrogen depletion","type":"exact"},{"name":"increased DNA recombination at telomere during nitrogen deprivation","type":"exact"},{"name":"increased DNA recombination frequency at telomere during nitrogen starvation","type":"related"},{"name":"increased DNA recombination rate at telomere during nitrogen starvation","type":"related"},{"name":"increased recombination at telomere during nitrogen starvation","type":"exact"}],"termid":"FYPO:0005407"}


id: GO:0032075
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of catalytic activity","termid":"GO:0043085"},{"relation_name":"is_a","term_name":"positive regulation of nucleobase-containing compound metabolic process","termid":"GO:0045935"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of nuclease activity","synonyms":[{"name":"activation of nuclease activity","type":"narrow"},{"name":"nuclease activator","type":"related"},{"name":"stimulation of nuclease activity","type":"narrow"},{"name":"up regulation of nuclease activity","type":"exact"},{"name":"up-regulation of nuclease activity","type":"exact"},{"name":"upregulation of nuclease activity","type":"exact"}],"termid":"GO:0032075"}


id: PBO:0041713
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"calmodulin like 4","termid":"PBO:0041713"}


id: SO:0001248
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A region of the genome of known length that is composed by ordering and aligning two or more different regions.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"experimental_feature","termid":"SO:0001410"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"assembly","secondary_identifiers":["http://en.wikipedia.org/wiki/Genome_assembly#Genome_assembly"],"termid":"SO:0001248"}


id: PBO:0050755
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heat shock protein family E (Hsp10) member 1 pseudogene 17","termid":"PBO:0050755"}


id: PBO:0045429
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dpy-19 like C-mannosyltransferase 1","termid":"PBO:0045429"}


id: PBO:0000000
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene characterisation status","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"published","termid":"PBO:0000000"}


id: PBO:0051330
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin kappa variable 2-24","termid":"PBO:0051330"}


id: PBO:0074400
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small integral membrane protein 9","termid":"PBO:0074400"}


id: MONDO:0003529
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Sudden onset pyelonephritis.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pyelonephritis","termid":"MONDO:0006939"},{"relation_name":"is_a","term_name":"acute disease","termid":"MONDO:0020683"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240"],"is_obsolete":false,"name":"acute pyelonephritis","secondary_identifiers":["icd11.foundation:441183088","UMLS:C0520575","MEDGEN:636072","NCIT:C123215","DOID:559","ICD10CM:N10","ICD9:590.1","SCTID:36689008"],"synonyms":[{"name":"pyelonephritis, acute","type":"exact"}],"termid":"MONDO:0003529","xrefs":{"Monarch":{"xref_id":"0003529"}}}


id: GO:0004452
data:
  {"annotated_genes":["SJAG_04307"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[76439],"is_not":false,"summary":null,"term":"GO:0004452"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: isopentenyl diphosphate = dimethylallyl diphosphate.","definition_xrefs":["RHEA:23284"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intramolecular oxidoreductase activity, transposing C=C bonds","termid":"GO:0016863"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04307":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016853"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016853","GO:0003824"],"is_obsolete":false,"name":"isopentenyl-diphosphate delta-isomerase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["MetaCyc:IPPISOM-RXN","Reactome:R-HSA-191382","KEGG_REACTION:R01123","EC:5.3.3.2"],"synonyms":[{"name":"IPP isomerase activity","type":"related"},{"name":"isopentenyl-diphosphate D-isomerase activity","type":"exact"},{"name":"isopentenyl-diphosphate delta3-delta2-isomerase activity","type":"related"},{"name":"isopentenylpyrophosphate delta-isomerase activity","type":"related"},{"name":"isopentenylpyrophosphate isomerase activity","type":"related"},{"name":"methylbutenylpyrophosphate isomerase activity","type":"related"}],"termid":"GO:0004452","terms_by_termid":{"GO:0004452":null}}


id: PR:Q03392
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A proliferating cell nuclear antigen that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO03781","PANTHER:PTHR11352:SF0"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proliferating cell nuclear antigen (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC16D10.09","secondary_identifiers":["UniProtKB:Q03392"],"synonyms":[{"name":"PCNA (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-PCNA","type":"exact"}],"termid":"PR:Q03392"}


id: GO:1904885
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The aggregation, arrangement and bonding together of a set of components to form a beta-catenin destruction complex.","definition_xrefs":["PMID:23169527","GOC:PARL","GOC:TermGenie","GOC:bf","PMID:17143292","GO_REF:0000079"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex assembly","termid":"GO:0065003"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0065003"}],"interesting_parent_ids":["GO:0044085","GO:0008150","GO:0065003"],"is_obsolete":false,"name":"beta-catenin destruction complex assembly","synonyms":[{"name":"23S APC complex assembly","type":"narrow"},{"name":"23S APC complex formation","type":"narrow"},{"name":"APC-Axin-1-beta-catenin complex assembly","type":"exact"},{"name":"APC-Axin-1-beta-catenin complex formation","type":"exact"},{"name":"Axin-APC-beta-catenin-GSK3B complex assembly","type":"exact"},{"name":"Axin-APC-beta-catenin-GSK3B complex formation","type":"exact"},{"name":"BDC assembly","type":"exact"},{"name":"BDC formation","type":"exact"},{"name":"beta-catenin degradation complex assembly","type":"exact"},{"name":"beta-catenin degradation complex formation","type":"exact"},{"name":"beta-catenin destruction complex formation","type":"exact"},{"name":"destruction complex formation","type":"related"}],"termid":"GO:1904885"}


id: FYECO:0000089
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which sodium oleate was added to the medium or assay buffer in excess compared to standard medium or assay buffers.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"+ fatty acid","termid":"FYECO:0000042"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ Na oleate","synonyms":[{"name":"sodium oleate added","type":"exact"}],"termid":"FYECO:0000089"}


id: GO:1901944
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving miltiradiene.","definition_xrefs":["GOC:TermGenie","PMID:22027823"],"direct_ancestors":[{"relation_name":"is_a","term_name":"terpene metabolic process","termid":"GO:0042214"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0006629","GO:0008150"],"is_obsolete":false,"name":"miltiradiene metabolic process","synonyms":[{"name":"miltiradiene metabolism","type":"exact"}],"termid":"GO:1901944"}


id: PBO:0071848
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S2 pseudogene 43","termid":"PBO:0071848"}


id: PBO:0027509
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_mitotic_chromosome_condensation","termid":"PBO:0027509"}


id: PBO:0089906
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"histone acetyltransferase, KAT5 family Mst1","termid":"PBO:0089906"}


id: MONDO:0008350
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pulmonic stenosis and deafness","secondary_identifiers":["MEDGEN:357273","OMIM:178651","UMLS:C1867406"],"synonyms":[{"name":"pulmonic stenosis and deafness","type":"exact"}],"termid":"MONDO:0008350","xrefs":{"Monarch":{"xref_id":"0008350"}}}


id: MONDO:0017538
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Preaxial polydactyly of toes","termid":"MONDO:0017457"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Preaxial polydactyly of toes, bilateral","secondary_identifiers":["Orphanet:295177","UMLS:C5437916","icd11.foundation:3040646","MEDGEN:1741594"],"synonyms":[{"name":"bifid great toes, bilateral","type":"exact"},{"name":"bifid halluces, bilateral","type":"exact"},{"name":"bifid hallux, bilateral","type":"exact"}],"termid":"MONDO:0017538","xrefs":{"Monarch":{"xref_id":"0017538"}}}


id: MONDO:0002503
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An astrocytic tumor occurring during adulthood. Representative examples include diffuse astrocytoma, anaplastic astrocytoma, and glioblastoma.","definition_xrefs":["NCIT:C7049"],"direct_ancestors":[{"relation_name":"is_a","term_name":"astrocytic tumor","termid":"MONDO:0021636"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"adult astrocytic tumor","secondary_identifiers":["UMLS:C1332183","DOID:3076","MEDGEN:272290"],"synonyms":[{"name":"adult astrocytic neoplasm","type":"exact"},{"name":"adult astrocytic tumor","type":"exact"},{"name":"adult astrocytoma","type":"exact"},{"name":"astrocytic tumor","type":"broad"},{"name":"astrocytic tumour","type":"broad"}],"termid":"MONDO:0002503","xrefs":{"Monarch":{"xref_id":"0002503"}}}


id: GO:0004000
data:
  {"annotated_genes":["SJAG_04189","SJAG_04380"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[75572],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0052717"},{"annotations":[73379],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0043829"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: adenosine + H2O = inosine + NH3.","definition_xrefs":["RHEA:24408"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines","termid":"GO:0016814"},{"relation_name":"is_a","term_name":"deaminase activity","termid":"GO:0019239"}],"gene_count":2,"genes_by_uniquename":{"SJAG_04189":null,"SJAG_04380":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0016810"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016787","GO:0016810"],"is_obsolete":false,"name":"adenosine deaminase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["MetaCyc:ADENODEAMIN-RXN","Reactome:R-HSA-5693346"],"synonyms":[{"name":"adenosine aminohydrolase activity","type":"related"},{"name":"adenosine deaminase reaction","type":"exact"}],"termid":"GO:0004000","terms_by_termid":{"GO:0043829":null,"GO:0052717":null}}


id: GO:0043839
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the transfer of a methyl group from S-adenosylmethionine (SAM) to the 1-phosphate group of lipid A.","definition_xrefs":["PMID:15994324"],"direct_ancestors":[{"relation_name":"is_a","term_name":"S-adenosylmethionine-dependent methyltransferase activity","termid":"GO:0008757"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016741"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016741","GO:0016740"],"is_obsolete":false,"name":"lipid A phosphate methyltransferase activity","synonyms":[{"name":"LmtA","type":"related"},{"name":"lipid A 1-phosphomethyltransferase activity","type":"exact"},{"name":"lipid A methyltransferase","type":"broad"},{"name":"lipid A phosphomethyltransferase activity","type":"exact"}],"termid":"GO:0043839"}


id: GO:0004586
data:
  {"annotated_genes":["SJAG_00043"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[77521],"is_not":false,"summary":null,"term":"GO:0004586"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: L-ornithine + H+ = CO2 + putrescine.","definition_xrefs":["EC:4.1.1.17","RHEA:22964"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxy-lyase activity","termid":"GO:0016831"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00043":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016829","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"ornithine decarboxylase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["MetaCyc:ORNDECARBOX-RXN","Reactome:R-HSA-70692","KEGG_REACTION:R00670"],"synonyms":[{"name":"L-ornithine carboxy-lyase (putrescine-forming)","type":"related"},{"name":"L-ornithine carboxy-lyase activity","type":"narrow"},{"name":"SpeC","type":"related"}],"termid":"GO:0004586","terms_by_termid":{"GO:0004586":null}}


id: PBO:0026804
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_meiotic_recombination_double-strand_break_repair","termid":"PBO:0026804"}


id: PBO:0050347
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heterogeneous nuclear ribonucleoprotein A1 pseudogene 50","termid":"PBO:0050347"}


id: MONDO:0034931
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete rare conjunctivitis (obsolete MONDO:0034931)","secondary_identifiers":["Orphanet:519280"],"termid":"MONDO:0034931","xrefs":{"Monarch":{"xref_id":"0034931"}}}


id: GO:0102953
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: glutathionate + hypoglycin A = L-cysteinylglycine + hypoglycin B.","definition_xrefs":["GOC:pz"],"direct_ancestors":[{"relation_name":"is_a","term_name":"aminoacyltransferase activity","termid":"GO:0016755"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016746","GO:0016740"],"is_obsolete":false,"name":"hypoglycin A gamma-glutamyl transpeptidase activity","secondary_identifiers":["MetaCyc:RXN-9157"],"termid":"GO:0102953"}


id: GO:0034211
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"GTP dependent catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate.","definition_xrefs":["GOC:ecd","PMID:17200152"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein serine/threonine kinase activity","termid":"GO:0004674"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0004672"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016301"}],"interesting_parent_ids":["GO:0016740","GO:0004672","GO:0140096","GO:0003824","GO:0016301","GO:0003674"],"is_obsolete":false,"name":"GTP-dependent protein kinase activity","termid":"GO:0034211"}


id: GO:0010657
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle.","definition_xrefs":["CL:0000187","GOC:tb","GOC:dph","GOC:mtg_apoptosis"],"direct_ancestors":[{"relation_name":"is_a","term_name":"apoptotic process","termid":"GO:0006915"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"muscle cell apoptotic process","synonyms":[{"name":"muscle cell apoptosis","type":"narrow"}],"termid":"GO:0010657"}


id: GO:0006366
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promoter","type":"exact"}],"termid":"GO:0006366","terms_by_termid":{"GO:0000122":null,"GO:0001174":null,"GO:0001193":null,"GO:0006357":null,"GO:0006366":null,"GO:0006367":null,"GO:0006368":null,"GO:0006369":null,"GO:0030847":null,"GO:0032968":null,"GO:0042789":null,"GO:0045815":null,"GO:0045899":null,"GO:0045944":null,"GO:0051123":null,"GO:0060261":null,"GO:0060963":null,"GO:0140673":null}}


id: MONDO:0859160
data:
  {"annotated_genes":["SJAG_03296"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88375],"is_not":false,"summary":null,"term":"MONDO:0859160"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"mitochondrial complex IV deficiency, nuclear-type","termid":"MONDO:0033885"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03296":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0004069"],"is_obsolete":false,"name":"mitochondrial complex IV deficiency, nuclear type 22","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:16448","DOID:0070507","UMLS:C5543491","OMIM:619355","MEDGEN:1786100"],"termid":"MONDO:0859160","terms_by_termid":{"MONDO:0859160":null},"xrefs":{"Monarch":{"xref_id":"0859160"}}}


id: MONDO:0007232
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Autosomal dominant brachyolmia is a relatively severe form of brachyolmia, a group of rare genetic skeletal disorders, characterized by short-trunked short stature, platyspondyly and kyphoscoliosis. Degenerative joint disease (osteoarthropathy) in the spine, large joints and interphalangeal joints becomes manifest in adulthood.","definition_xrefs":["Orphanet:93304"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant disease","termid":"MONDO:0000426"},{"relation_name":"is_a","term_name":"brachyolmia","termid":"MONDO:0015262"},{"relation_name":"is_a","term_name":"TRPV4-related bone disorder","termid":"MONDO:0018240"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"},{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0005497","MONDO:0000426"],"is_obsolete":false,"name":"autosomal dominant brachyolmia","secondary_identifiers":["SCTID:717264003","UMLS:C0432227","MEDGEN:96583","OMIM:113500","GARD:10429"],"synonyms":[{"name":"BCYM3","type":"related"},{"name":"brachyolmia autosomal dominant","type":"related"},{"name":"brachyolmia type 3","type":"exact"},{"name":"brachyolmia, autosomal dominant","type":"exact"},{"name":"brachyrachia","type":"related"}],"termid":"MONDO:0007232","xrefs":{"Monarch":{"xref_id":"0007232"}}}


id: PBO:0031266
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_cell_separation_after_cytokinesis","termid":"PBO:0031266"}


id: PBO:0066149
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RBBP4 pseudogene 5","termid":"PBO:0066149"}


id: MONDO:0008460
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Splenogonadal fusion-limb defects-micrognatia syndrome is a rare dysostosis syndrome characterized by abnormal fusion of the spleen with the gonad (or more rarely with remnants of the mesonephros), limb abnormalities (consisting of amelia or severe reduction defects leading to upper and/or lower rudimentary limbs) and orofacial abnormalities such as cleft palate, bifid uvula, microglossia and mandibular hypoplasia. It could also be associated with other malformations such as cryptorchidism, anal stenosis/atresia, hypoplastic lungs and cardiac malformations.","definition_xrefs":["Orphanet:2063"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"dysostosis","termid":"MONDO:0018234"},{"relation_name":"is_a","term_name":"congenital limb malformation","termid":"MONDO:0019054"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"splenogonadal fusion-limb defects-micrognathia syndrome","secondary_identifiers":["GARD:4963","OMIM:183300","MEDGEN:401073","MESH:C537318","SCTID:726724005","UMLS:C1866745"],"synonyms":[{"name":"SGFLD syndrome","type":"exact"},{"name":"Sgfld syndrome","type":"related"},{"name":"splenogonadal fusion limb defect syndrome","type":"related"},{"name":"splenogonadal fusion limb defects micrognatia","type":"related"},{"name":"splenogonadal fusion limb defects syndrome","type":"related"},{"name":"splenogonadal fusion with limb defects and micrognathia","type":"related"}],"termid":"MONDO:0008460","xrefs":{"Monarch":{"xref_id":"0008460"}}}


id: GO:0044156
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A plasma membrane part that forms a specialized region of connection between two host cells or between a host cell and the host extracellular matrix. At a host cell junction, anchoring proteins extend through the host plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.","definition_xrefs":["GOC:rph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"host cell part","termid":"GO:0033643"},{"relation_name":"part_of","term_name":"host cell plasma membrane","termid":"GO:0020002"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"host cell junction","termid":"GO:0044156"}


id: GO:0102781
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: H+ + isofucosterol + O2 + NADPH = (22alpha)-hydroxy-isofucosterol + H2O + NADP.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete isofucosterol hydroxylase activity (obsolete GO:0102781)","termid":"GO:0102781"}


id: PBO:0040019
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"armadillo repeat containing 8","termid":"PBO:0040019"}


id: MONDO:0021444
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign neoplasm that involves the large intestine.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intestinal benign neoplasm","termid":"MONDO:0003062"},{"relation_name":"is_a","term_name":"large intestine disorder","termid":"MONDO:0024634"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"benign neoplasm of large intestine","secondary_identifiers":["NCIT:C4610","SCTID:92170008","UMLS:C0347272","MEDGEN:91125"],"synonyms":[{"name":"benign colorectal neoplasm","type":"exact"},{"name":"benign colorectal neoplasms","type":"exact"},{"name":"benign colorectal tumor","type":"exact"},{"name":"benign colorectal tumors","type":"exact"},{"name":"benign colorectal tumour","type":"exact"},{"name":"benign colorectal tumours","type":"exact"},{"name":"benign large bowel neoplasm","type":"exact"},{"name":"benign large bowel tumor","type":"exact"},{"name":"benign large bowel tumour","type":"exact"},{"name":"benign large intestine neoplasm","type":"exact"},{"name":"benign large intestine tumor","type":"exact"},{"name":"benign large intestine tumour","type":"exact"},{"name":"benign neoplasm of large bowel","type":"exact"},{"name":"benign neoplasm of the large bowel","type":"exact"},{"name":"benign neoplasm of the large intestine","type":"exact"},{"name":"benign tumor of large bowel","type":"exact"},{"name":"benign tumor of large intestine","type":"exact"},{"name":"benign tumor of the large bowel","type":"exact"},{"name":"benign tumor of the large intestine","type":"exact"},{"name":"benign tumour of large bowel","type":"exact"},{"name":"benign tumour of large intestine","type":"exact"},{"name":"benign tumour of the large bowel","type":"exact"},{"name":"benign tumour of the large intestine","type":"exact"},{"name":"colorectal neoplasms, benign","type":"exact"},{"name":"colorectal tumors, benign","type":"exact"},{"name":"large intestine benign neoplasm","type":"exact"},{"name":"neoplasms, colorectal, benign","type":"exact"},{"name":"tumors, colorectal, benign","type":"exact"}],"termid":"MONDO:0021444","xrefs":{"Monarch":{"xref_id":"0021444"}}}


id: GO:0046299
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds.","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete 2,4-dichlorophenoxyacetic acid biosynthetic process (obsolete GO:0046299)","synonyms":[{"name":"2,4-dichlorophenoxyacetic acid anabolism","type":"exact"},{"name":"2,4-dichlorophenoxyacetic acid biosynthesis","type":"exact"},{"name":"2,4-dichlorophenoxyacetic acid biosynthetic process","type":"exact"},{"name":"2,4-dichlorophenoxyacetic acid formation","type":"exact"},{"name":"2,4-dichlorophenoxyacetic acid synthesis","type":"exact"}],"termid":"GO:0046299"}


id: PBO:0040092
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"arylsulfatase L","termid":"PBO:0040092"}


id: FYPO:0008176
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which RNAs transcribed from the centromere inner repeat region are present at greater levels than normal.","direct_ancestors":[{"relation_name":"is_a","term_name":"increased centromeric transcript level","termid":"FYPO:0004982"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0006551"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0006551","FYPO:0005447","FYPO:0001985","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"increased centromeric inner repeat transcript level","termid":"FYPO:0008176"}


id: GO:0180022
data:
  {"annotated_genes":["SJAG_00898","SJAG_02096","SJAG_03189"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[65366,105064,118090],"is_not":false,"summary":null,"term":"GO:0180022"}]},"cv_name":"cellular_component","definition":"A ribosome disassembly complex which dissociates stalled ribsome subunits as part of the ribosome quality control pathway. RQT complex is composed of a RNA helicase-family protein yeast Rqt2 (human ASCC3), a ubiquitin-binding protein yeast Rqt3, (human ASCC2), and Rqt4 (human TRIP4). The human complex has an additional component protein ASCC1 and can act as a transcriptional coactivator by interacting with transcription factors such as NF-kappa B.","definition_xrefs":["PMID:12077347","PMID:32099016","PMID:28757607"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex","termid":"GO:0032991"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00898":null,"SJAG_02096":null,"SJAG_03189":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"RQC-trigger complex","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000107":null},"synonyms":[{"name":"ASC-1 complex","type":"exact"},{"name":"RQT complex","type":"exact"},{"name":"activating signal cointegrator 1 complex","type":"exact"}],"termid":"GO:0180022","terms_by_termid":{"GO:0180022":null}}


id: GO:0045716
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein receptors.","definition_xrefs":["GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of low-density lipoprotein particle receptor biosynthetic process (obsolete GO:0045716)","synonyms":[{"name":"activation of low-density lipoprotein receptor biosynthetic process","type":"narrow"},{"name":"positive regulation of low-density lipoprotein receptor anabolism","type":"exact"},{"name":"positive regulation of low-density lipoprotein receptor biosynthesis","type":"exact"},{"name":"positive regulation of low-density lipoprotein receptor biosynthetic process","type":"exact"},{"name":"positive regulation of low-density lipoprotein receptor formation","type":"exact"},{"name":"positive regulation of low-density lipoprotein receptor synthesis","type":"exact"},{"name":"stimulation of low-density lipoprotein receptor biosynthetic process","type":"narrow"},{"name":"up regulation of low-density lipoprotein receptor biosynthetic process","type":"exact"},{"name":"up-regulation of low-density lipoprotein receptor biosynthetic process","type":"exact"},{"name":"upregulation of low-density lipoprotein receptor biosynthetic process","type":"exact"}],"termid":"GO:0045716"}


id: PBO:0075735
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SRP14 pseudogene 3","termid":"PBO:0075735"}


id: PBO:0055242
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2669","termid":"PBO:0055242"}


id: FYPO:0000334
data:
  {"alleles_by_uniquename":{"SJAG_00370:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_00370","name":"erg1delta","uniquename":"SJAG_00370:allele-1"},"SJAG_00426:allele-1":{"allele_type":"amino_acid_mutation","description":"P363S","gene_uniquename":"SJAG_00426","name":"bbl1-P363S","uniquename":"SJAG_00426:allele-1"},"SJAG_01143:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01143","name":"mid1delta","uniquename":"SJAG_01143:allele-1"},"SJAG_01242:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01242","name":"vps32delta","uniquename":"SJAG_01242:allele-1"},"SJAG_01374:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01374","name":"nup132delta","uniquename":"SJAG_01374:allele-1"},"SJAG_01745:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01745","name":"lem2delta","uniquename":"SJAG_01745:allele-1"},"SJAG_01906:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01906","name":"nem1delta","uniquename":"SJAG_01906:allele-1"},"SJAG_02392:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02392","name":"pom1delta","uniquename":"SJAG_02392:allele-1"},"SJAG_02592:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02592","name":"sty1delta","uniquename":"SJAG_02592:allele-1"},"SJAG_02763:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02763","name":"ned1delta","uniquename":"SJAG_02763:allele-1"},"SJAG_02763:allele-2":{"allele_type":"amino_acid_mutation","description":"D422E,D424E","gene_uniquename":"SJAG_02763","name":"ned1cat","synonyms":[{"name":"Catalytic mutant","reference":"PMID:26774782","type":"exact"}],"uniquename":"SJAG_02763:allele-2"},"SJAG_02763:allele-3":{"allele_type":"amino_acid_mutation","description":"S235A; S651","gene_uniquename":"SJAG_02763","name":"ned1S235A/S651","synonyms":[{"name":"refractory to phosphorylation","reference":"PMID:26774782","type":"exact"}],"uniquename":"SJAG_02763:allele-3"},"SJAG_02763:allele-4":{"allele_type":"amino_acid_mutation","description":"S235E; S651E","gene_uniquename":"SJAG_02763","name":"ned1S235E/S651E","synonyms":[{"name":"phosphomimetic","reference":"PMID:26774782","type":"exact"}],"uniquename":"SJAG_02763:allele-4"},"SJAG_02763:allele-5":{"allele_type":"amino_acid_mutation","description":"S499E; S538E; T620E; T638E; S651E","gene_uniquename":"SJAG_02763","name":"ned1-5E","uniquename":"SJAG_02763:allele-5"},"SJAG_02763:allele-6":{"allele_type":"amino_acid_mutation","description":"S499A; S538A; T620A; T638A; S651A","gene_uniquename":"SJAG_02763","name":"ned1-5A","synonyms":[{"name":"refractory to potential proline-directed kinase 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id: FYPO:0006402
data:
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id: PBO:0087320
data:
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id: GO:0001850
data:
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id: GO:0075106
data:
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id: PBO:0083696
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Epsilon-COP subunit of the coatomer; regulates retrograde Golgi-to-ER protein traffic; stabilizes Cop1p, the alpha-COP and the coatomer complex; non-essential for cell growth; protein abundance increases in response to DNA replication stress","termid":"PBO:0083696"}


id: PBO:0086311
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein with rhodanese activity; contains a rhodanese-like domain similar to Rdl1p, Uba4p, Tum1p, and Ych1p; overexpression causes a cell cycle delay; null mutant displays elevated frequency of mitochondrial genome loss","termid":"PBO:0086311"}


id: SO:0000185
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A transcript that in its initial state requires modification to be functional.","definition_xrefs":["SO:ma"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transcript","termid":"SO:0000673"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"primary_transcript","secondary_identifiers":["http://en.wikipedia.org/wiki/Primary_transcript"],"synonyms":[{"name":"INSDC_feature:precursor_RNA","type":"exact"},{"name":"INSDC_feature:prim_transcript","type":"exact"},{"name":"precursor RNA","type":"exact"},{"name":"primary transcript","type":"exact"}],"termid":"SO:0000185"}


id: PR:Q9P4X3
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- utp7 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9P4X3"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"U3 small nucleolar RNA-associated protein 7 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC959.03c","synonyms":[{"name":"Spom972h-utp7","type":"exact"},{"name":"U three protein 7 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"U3 snoRNA-associated protein 7 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9P4X3"}


id: MONDO:0022482
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete apolipoprotein C 2i deficiency (obsolete MONDO:0022482)","termid":"MONDO:0022482","xrefs":{"Monarch":{"xref_id":"0022482"}}}


id: PBO:0066853
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RN7SK pseudogene 153","termid":"PBO:0066853"}


id: MONDO:1011815
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"cancer or benign tumor, non-human animal","termid":"MONDO:1011305"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"renal cystadenocarcinoma and nodular dermatofibrosis, non-human animal","secondary_identifiers":["OMIA:001335"],"termid":"MONDO:1011815","xrefs":{"Monarch":{"xref_id":"1011815"}}}


id: PBO:0002422
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribonucleoside reductase large subunit Cdc22","termid":"PBO:0002422"}


id: PBO:0072609
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal L24 domain containing 1 pseudogene 4","termid":"PBO:0072609"}


id: PBO:0044983
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DEAH-box helicase 35","termid":"PBO:0044983"}


id: GO:0090265
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the rate, frequency, or extent of the process of immune complex clearance by monocytes or macrophages.","definition_xrefs":["GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of immune effector process","termid":"GO:0002699"},{"relation_name":"is_a","term_name":"regulation of immune complex clearance by monocytes and macrophages","termid":"GO:0090264"},{"relation_name":"positively_regulates","term_name":"immune complex clearance by monocytes and macrophages","termid":"GO:0002436"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of immune complex clearance by monocytes and macrophages","termid":"GO:0090265"}


id: PBO:0065764
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peptide YY","termid":"PBO:0065764"}


id: PBO:0044820
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"defensin beta 109C","termid":"PBO:0044820"}


id: PBO:0111850
data:
  {"annotation_feature_type":"gene","cv_name":"pombase_family_or_domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RecA family","termid":"PBO:0111850"}


id: GO:0071885
data:
  {"annotated_genes":["SJAG_01425","SJAG_00508"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[64930,79129],"is_not":false,"summary":null,"term":"GO:0071885"}]},"cv_name":"molecular_function","definition":"Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the alpha-amino group of the N-terminal amino or imino acid residue of a protein substrate. For example, yeast Tae1p and mammalian family member METTL11A preferentially modify the N-terminal residue of substrates with the N-terminal sequence X-Pro-Lys, where X can be Pro, Ala, or Ser.","definition_xrefs":["PMID:20481588"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein methyltransferase activity","termid":"GO:0008276"},{"relation_name":"is_a","term_name":"S-adenosylmethionine-dependent methyltransferase activity","termid":"GO:0008757"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00508":null,"SJAG_01425":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0008276"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0008276","GO:0003674","GO:0003824","GO:0016740","GO:0140096","GO:0016741"],"is_obsolete":false,"name":"N-terminal protein N-methyltransferase activity","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000104":null},"secondary_identifiers":["EC:2.1.1.244"],"synonyms":[{"name":"X-Pro-Lys N-terminal methyltransferase","type":"narrow"}],"termid":"GO:0071885","terms_by_termid":{"GO:0071885":null}}


id: PBO:0071659
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RPL37A divergent transcript","termid":"PBO:0071659"}


id: PATO:0005009
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A 3-D shape inhering in a bearer by virtue of the bearer's having an entity in the form of a molar tooth.","definition_xrefs":["PATOC:WD"],"direct_ancestors":[{"relation_name":"is_a","term_name":"3-D shape","termid":"PATO:0002266"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"molariform","termid":"PATO:0005009"}


id: PBO:0052123
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"potassium voltage-gated channel subfamily E regulatory subunit 1","termid":"PBO:0052123"}


id: MONDO:0007234
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"branchial myoclonus with spastic paraparesis and cerebellar ataxia","secondary_identifiers":["UMLS:C1862071","OMIM:113610","MEDGEN:349424","MESH:C566188"],"synonyms":[{"name":"branchial myoclonus with spastic paraparesis and cerebellar ataxia","type":"exact"}],"termid":"MONDO:0007234","xrefs":{"Monarch":{"xref_id":"0007234"}}}


id: MONDO:0006886
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A thyroid neoplasm of mixed papillary and follicular arrangement. Its biological behavior and prognosis is the same as that of a papillary adenocarcinoma of the thyroid. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1271)","definition_xrefs":["MESH:D018265"],"direct_ancestors":[{"relation_name":"is_a","term_name":"thyroid gland follicular carcinoma","termid":"MONDO:0005034"},{"relation_name":"is_a","term_name":"thyroid gland papillary carcinoma","termid":"MONDO:0005075"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"thyroid gland papillary and follicular carcinoma","secondary_identifiers":["NCIT:C7380","DOID:3968","MEDGEN:64631","UMLS:C0206683","EFO:1001083"],"synonyms":[{"name":"papillary and follicular adenocarcinoma","type":"exact"},{"name":"papillary and follicular carcinoma","type":"exact"},{"name":"papillary follicular thyroid adenocarcinoma","type":"related"},{"name":"thyroid gland papillary and follicular carcinoma","type":"exact"}],"termid":"MONDO:0006886","xrefs":{"Monarch":{"xref_id":"0006886"}}}


id: PBO:0040539
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"B3GALT5 antisense RNA 1","termid":"PBO:0040539"}


id: PBO:0086544
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative protein of unknown function; conserved among S. cerevisiae strains; YDR029W is not an essential gene","termid":"PBO:0086544"}


id: PBO:0065626
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein tyrosine phosphatase non-receptor type 4","termid":"PBO:0065626"}


id: MONDO:0700098
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"cancer or benign tumor, non-human animal","termid":"MONDO:1011305"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"neoplasm, non-human animal","termid":"MONDO:0700098","xrefs":{"Monarch":{"xref_id":"0700098"}}}


id: PBO:0066121
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RASSF1 antisense RNA 1","termid":"PBO:0066121"}


id: PBO:0113472
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of TORC2, a regulator of plasma membrane (PM) homeostasis; TORC2 also regulates actin cytoskeletal dynamics during polarized growth and cell wall integrity; interacts with Slm1p and Slm2p, homologous PH domain-containing TORC2 substrates; BIT2 has a paralog, BIT61, that arose from the whole genome duplication","termid":"PBO:0113472"}


id: GO:0004454
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 1-phosphate.","definition_xrefs":["EC:2.7.1.3"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphotransferase activity, alcohol group as acceptor","termid":"GO:0016773"},{"relation_name":"is_a","term_name":"carbohydrate kinase activity","termid":"GO:0019200"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016301"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016740","GO:0016301","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"ketohexokinase activity","secondary_identifiers":["Reactome:R-HSA-70333","Reactome:R-HSA-5656459","RHEA:18145","MetaCyc:KETOHEXOKINASE-RXN"],"synonyms":[{"name":"ATP:D-fructose 1-phosphotransferase activity","type":"related"},{"name":"hepatic fructokinase activity","type":"narrow"},{"name":"ketohexokinase (phosphorylating)","type":"related"}],"termid":"GO:0004454"}


id: SO:0000072
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","gene_count":0,"genotype_count":0,"name":"OBSOLETE SO:0000072 end_overlapping_gene (obsolete SO:0000072)","termid":"SO:0000072"}


id: GO:0000025
data:
  {"annotated_genes":["SJAG_02131","SJAG_03824"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[103529,103530],"is_not":false,"summary":null,"term":"GO:0000025"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose).","definition_xrefs":["GOC:jl","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"maltose metabolic process","termid":"GO:0000023"},{"relation_name":"is_a","term_name":"disaccharide catabolic process","termid":"GO:0046352"}],"gene_count":2,"genes_by_uniquename":{"SJAG_02131":null,"SJAG_03824":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0008150","GO:0005975"],"is_obsolete":false,"name":"maltose catabolic process","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["MetaCyc:MALTOSECAT-PWY"],"synonyms":[{"name":"malt sugar catabolic process","type":"exact"},{"name":"malt sugar catabolism","type":"exact"},{"name":"maltose breakdown","type":"exact"},{"name":"maltose degradation","type":"exact"},{"name":"maltose hydrolysis","type":"narrow"}],"termid":"GO:0000025","terms_by_termid":{"GO:0000025":null}}


id: PBO:0085485
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Processing alpha glucosidase I; ER type II integral membrane N-glycoprotein involved in assembly of cell wall beta 1,6 glucan and asparagine-linked protein glycosylation; also involved in ER protein quality control and sensing of ER stress","termid":"PBO:0085485"}


id: FYPO:0006535
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the localization of a protein to the cell periphery is increased when the cell is subject to nitrogen starvation.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein localization to cell periphery","termid":"FYPO:0006533"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000138","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"increased protein localization to cell periphery during nitrogen starvation","synonyms":[{"name":"increased protein localisation to cell periphery during nitrogen starvation","type":"exact"},{"name":"increased protein localization to cell periphery during nitrogen depletion","type":"exact"},{"name":"increased protein localization to cell periphery during nitrogen deprivation","type":"exact"}],"termid":"FYPO:0006535"}


id: PBO:0085951
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein of unknown function; null mutant is defective in unfolded protein response; possibly involved in a membrane regulation metabolic pathway; member of the PhzF superfamily, though most likely not involved in phenazine production","termid":"PBO:0085951"}


id: MONDO:0032592
data:
  {"annotated_genes":["SJAG_01139"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88101],"is_not":false,"summary":null,"term":"MONDO:0032592"}]},"cv_name":"mondo","definition":"A dilated cardiomyopathy that is characterized by dilated cardiomyopathy of variable severity, with age of onset ranging from 2 to 20 years and that has material basis in homozygous or compound heterozygous mutation in the PPCS gene on chromosome 1p34.","definition_xrefs":["DOID:0081159"],"direct_ancestors":[{"relation_name":"is_a","term_name":"familial isolated dilated cardiomyopathy","termid":"MONDO:0700335"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01139":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"cardiomyopathy, dilated, 2c","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:16305","OMIM:618189","MEDGEN:1648379","UMLS:C4748647"],"synonyms":[{"name":"CARDIOMYOPATHY, DILATED, 2C","type":"related"},{"name":"CMD2C","type":"related"}],"termid":"MONDO:0032592","terms_by_termid":{"MONDO:0032592":null},"xrefs":{"Monarch":{"xref_id":"0032592"}}}


id: PBO:0002930
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3.4.14.10","termid":"PBO:0002930"}


id: MONDO:0030988
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"developmental delay with dysmorphic facies and dental anomalies","secondary_identifiers":["UMLS:C5543197","OMIM:619228","MEDGEN:1785587"],"synonyms":[{"name":"DEFDA","type":"exact"}],"termid":"MONDO:0030988","xrefs":{"Monarch":{"xref_id":"0030988"}}}


id: MONDO:0006842
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A neoplasm with perivascular epithelioid cell differentiation, often associated with tuberous sclerosis. It is characterized by the presence of smooth muscle and epithelioid cells and by the proliferation of lymphatic vessels. Sites of involvement include the lymph nodes, lung, mediastinum, and retroperitoneum.","definition_xrefs":["NCIT:C3204"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neoplasm with perivascular epithelioid cell differentiation","termid":"MONDO:0006359"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lymphangiomyoma","secondary_identifiers":["MEDGEN:44216","EFO:1001027","ICDO:9174/0","UMLS:C0024223","MESH:D008203"],"synonyms":[{"name":"lymphangioleiomyoma","type":"exact"},{"name":"lymphangiomyoma","type":"exact"}],"termid":"MONDO:0006842","xrefs":{"Monarch":{"xref_id":"0006842"}}}


id: PATO:0002057
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"An area which is relatively high.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"increased_in_magnitude_relative_to","term_name":"normal","termid":"PATO:0000461"},{"relation_name":"is_a","term_name":"increased size","termid":"PATO:0000586"},{"relation_name":"is_a","term_name":"area","termid":"PATO:0001323"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"increased area","termid":"PATO:0002057"}


id: PR:Q9UUA8
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- saw1 gene.","definition_xrefs":["UniProtKB:Q9UUA8","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C409.16c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC409.16c","synonyms":[{"name":"Spom972h-saw1","type":"exact"}],"termid":"PR:Q9UUA8"}


id: GO:0008583
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which an undifferentiated cell acquires the features of a mystery cell. The mystery cells are a precluster of cells that emerge from the compound eye morphogenetic furrow, normally positioned between R3 and R4. They then disappear into the surrounding pool of undifferentiated cells and have no known fate in the mature ommatidium. An example of this process is found in Drosophila melanogaster.","definition_xrefs":["ISBN:0632030488","PMID:1295747"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell differentiation","termid":"GO:0030154"},{"relation_name":"part_of","term_name":"compound eye morphogenesis","termid":"GO:0001745"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mystery cell differentiation","termid":"GO:0008583"}


id: FYPO:0000983
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of glutamate dehydrogenase activity using NAPD+ as a cofactor is decreased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased oxidoreductase activity","termid":"FYPO:0000690"},{"relation_name":"is_a","term_name":"abnormal glutamate dehydrogenase (NADP+) activity","termid":"FYPO:0000982"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000707"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000661","FYPO:0000654","FYPO:0000652","FYPO:0000707"],"is_obsolete":false,"name":"decreased glutamate dehydrogenase (NADP+) activity","synonyms":[{"name":"decreased NAD(P)H-dependent glutamate dehydrogenase activity","type":"exact"},{"name":"decreased NADP-GDH activity","type":"exact"},{"name":"reduced glutamate dehydrogenase (NADP+) activity","type":"exact"}],"termid":"FYPO:0000983"}


id: SO:0002189
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A (unitary) pseudogene that is stable in the population but importantly it has a functional alternative allele also in the population. i.e., one strain may have the gene, another strain may have the pseudogene. MHC haplotypes have allelic pseudogenes.","direct_ancestors":[{"relation_name":"is_a","term_name":"unitary_pseudogene","termid":"SO:0001759"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"allelic_pseudogene","synonyms":[{"name":"INSDC_feature:gene","type":"broad"},{"name":"INSDC_qualifier:allelic","type":"exact"},{"name":"allelic pseudogene","type":"exact"}],"termid":"SO:0002189"}


id: PR:P18253
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- ppi1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:P18253"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peptidyl-prolyl cis-trans isomerase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC28F2.03","synonyms":[{"name":"CPH (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Cyclophilin (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"PPIase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Rotamase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-ppi1","type":"exact"},{"name":"cyclosporin A-binding protein (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:P18253"}


id: PBO:0002155
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fork head transcription factor Fhl1","termid":"PBO:0002155"}


id: PBO:0002132
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"40S ribosomal protein S24 (predicted)","termid":"PBO:0002132"}


id: GO:0102632
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (S)-scoulerine + [reduced NADPH--hemoprotein reductase] + O2 -> (S)-nandinine + [oxidized NADPH--hemoprotein reductase] + 2 H2O.","definition_xrefs":["GOC:pz","RHEA:50364","PMID:17250743","PMID:21094631"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water","termid":"GO:0016717"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"(S)-nandinine synthase activity","secondary_identifiers":["MetaCyc:RXN-15538","EC:1.14.19.73"],"termid":"GO:0102632"}


id: PBO:0055382
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2812","termid":"PBO:0055382"}


id: PBO:0045548
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dual specificity phosphatase 3","termid":"PBO:0045548"}


id: PBO:0056826
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MAX dimerization protein MGA","termid":"PBO:0056826"}


id: PBO:0077127
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TINAG antisense RNA 1","termid":"PBO:0077127"}


id: FYPO:0004761
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone exchange occurs to a greater extent than normal in regions of pericentric heterochromatin. Histone exchange is replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits.","definition_xrefs":["GO:0043486","PomBase:mah","GO:0005721","PMID:24095277"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal chromatin remodeling","termid":"FYPO:0006356"},{"relation_name":"is_a","term_name":"increased protein exchange at pericentric heterochromatin","termid":"FYPO:0006360"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000641"}],"interesting_parent_ids":["FYPO:0000641","FYPO:0001985","FYPO:0000138","FYPO:0005447","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"increased histone exchange at pericentric heterochromatin","synonyms":[{"name":"increased histone exchange at dh repeat","type":"narrow"},{"name":"increased histone exchange at pericentric heterochromatin during mitotic cell cycle","type":"related"},{"name":"increased histone exchange at pericentric heterochromatin during vegetative growth","type":"exact"}],"termid":"FYPO:0004761"}


id: PBO:0056143
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiosis 1 associated protein","termid":"PBO:0056143"}


id: PBO:0088693
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"exoribonuclease Rex4","termid":"PBO:0088693"}


id: PBO:0068226
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 533","termid":"PBO:0068226"}


id: PBO:0027211
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_level_of_amino_acid_import_gene_mRNA_during_vegetative_growth","termid":"PBO:0027211"}


id: MONDO:0011861
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"breath-holding Spells","secondary_identifiers":["UMLS:C0476287","OMIM:607578","MEDGEN:105400"],"synonyms":[{"name":"Bhs","type":"related"},{"name":"breath-holding Spells","type":"exact"}],"termid":"MONDO:0011861","xrefs":{"Monarch":{"xref_id":"0011861"}}}


id: GO:0006306
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.","definition_xrefs":["GOC:ems","ISBN:0198506732"],"gene_count":0,"genotype_count":0,"name":"obsolete DNA methylation (obsolete GO:0006306)","secondary_identifiers":["Wikipedia:DNA_methylation"],"termid":"GO:0006306"}


id: GO:0018263
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The formation of an isopeptide cross-link between peptidyl-asparagine and peptidyl-cysteine to produce N-(L-isoaspartyl)-L-cysteine.","definition_xrefs":["RESID:AA0216"],"gene_count":0,"genotype_count":0,"name":"obsolete isopeptide cross-linking via N-(L-isoaspartyl)-L-cysteine (obsolete GO:0018263)","termid":"GO:0018263"}


id: RO:HOM0000010
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"Structural homology that is detected by similarity in content and organization between chromosomes.","definition_xrefs":["MeSH:Synteny"],"direct_ancestors":[{"relation_name":"is_a","term_name":"in_structural_homology_relationship_with","termid":"RO:HOM0000006"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"in_syntenic_homology_relationship_with","synonyms":[{"name":"syntenic homologous to","type":"exact"},{"name":"synteny","type":"related"}],"termid":"RO:HOM0000010"}


id: GO:1990332
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A type-I transmembrane protein complex located in the endoplasmic reticulum (ER) consisting of an IRE1-IRE1 dimer, which forms in response to the accumulation of unfolded protein in the ER. The dimeric complex has endoribonuclease (RNase) activity and evokes the unfolded protein response (UPR) by cleaving an intron of a mRNA coding for the transcription factor HAC1 in yeast or XBP1 in mammals; the complex cleaves a single phosphodiester bond in each of two RNA hairpins (with non-specific base paired stems and loops of consensus sequence CNCNNGN, where N is any base) to remove an intervening intron from the target transcript.","definition_xrefs":["PMID:25437541","GOC:bf","GOC:bhm","PMID:18191223"],"direct_ancestors":[{"relation_name":"is_a","term_name":"membrane protein complex","termid":"GO:0098796"},{"relation_name":"is_a","term_name":"endoplasmic reticulum protein-containing complex","termid":"GO:0140534"},{"relation_name":"is_a","term_name":"serine/threonine protein kinase complex","termid":"GO:1902554"},{"relation_name":"is_a","term_name":"endoribonuclease complex","termid":"GO:1902555"},{"relation_name":"part_of","term_name":"endoplasmic reticulum membrane","termid":"GO:0005789"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005789"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005783"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0032991","GO:0005737","GO:0005783","GO:0005575","GO:0005789"],"is_obsolete":false,"name":"Ire1 complex","synonyms":[{"name":"ER-bound kinase/endoribonuclease (RNase), inositol-requiring enzyme-1","type":"exact"},{"name":"ERN1 complex","type":"related"},{"name":"IRE1 dimer","type":"exact"},{"name":"Ire1 complex dimer","type":"exact"},{"name":"Ire1 complex homodimer","type":"exact"},{"name":"Ire1 complex homooligomer","type":"exact"}],"termid":"GO:1990332"}


id: GO:0015151
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of alpha-glucosides from one side of a membrane to the other. Alpha-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration.","definition_xrefs":["PMID:28510148","GOC:mtg_transport","ISBN:0198506732","ISBN:0815340729","GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glucoside transmembrane transporter activity","termid":"GO:0042947"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0022857","GO:0005215","GO:0003674"],"is_obsolete":false,"name":"alpha-glucoside transmembrane transporter activity","termid":"GO:0015151"}


id: PBO:0046458
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"epidermal growth factor receptor pathway substrate 15 like 1","termid":"PBO:0046458"}


id: PBO:0005187
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3.1.3.15","termid":"PBO:0005187"}


id: GO:0098778
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The secretion of soluble curli subunits through the outer membrane, coupled to nucleation of curli fiber formation at the membrane surface.","definition_xrefs":["PMID:24080089"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein secretion by the type VIII secretion system","termid":"GO:0098777"},{"relation_name":"part_of","term_name":"curli assembly","termid":"GO:0098775"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044085","GO:0008150","GO:0051179","GO:0006810","GO:0055085"],"is_obsolete":false,"name":"curli subunit secretion coupled to curli assembly","synonyms":[{"name":"extracellular nucleation-precipitation pathway","type":"exact"}],"termid":"GO:0098778"}


id: FYPO:0007844
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the monomethylation of lysine at position 9 of histone H3 in centromere inner repeat regions occurs to a greater extent than normal.","definition_xrefs":["PomBase:mah","PMID:17363370"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased histone H3-K9 methylation at centromere during vegetative growth","termid":"FYPO:0005066"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002274"}],"interesting_parent_ids":["FYPO:0002494","FYPO:0001985","FYPO:0005447","FYPO:0002274","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"increased histone H3-K9 monomethylation at centromere during vegetative growth","synonyms":[{"name":"increased centromeric histone H3-K9 monomethylation during vegetative growth","type":"exact"},{"name":"increased histone H3 K9 monomethylation at centromere during vegetative growth","type":"exact"},{"name":"increased histone H3-K9 monomethylation at centromere during mitotic cell cycle","type":"related"},{"name":"increased histone H3K9 monomethylation at centromere during vegetative growth","type":"exact"},{"name":"increased histone lysine H3 K9 monomethylation at centromere during vegetative growth","type":"exact"}],"termid":"FYPO:0007844"}


id: GO:0031379
data:
  {"annotated_genes":["SJAG_03193","SJAG_03356","SJAG_02725"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[119992,71887,73677],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031380"}]},"cv_name":"cellular_component","definition":"A protein complex that possesses RNA-directed RNA polymerase activity.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA polymerase complex","termid":"GO:0030880"}],"gene_count":3,"genes_by_uniquename":{"SJAG_02725":null,"SJAG_03193":null,"SJAG_03356":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"RNA-directed RNA polymerase complex","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0031379","terms_by_termid":{"GO:0031380":null}}


id: GO:0031657
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that controls the frequency, rate or extent of G1 cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle.","definition_xrefs":["GOC:mtg_cell_cycle","GOC:pr"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle (obsolete GO:0031657)","synonyms":[{"name":"G1/S-specific regulation of cyclin-dependent protein kinase activity","type":"exact"},{"name":"regulation of cyclin-dependent protein kinase activity during G1/S","type":"related"},{"name":"regulation of cyclin-dependent protein kinase activity involved in G1/S","type":"broad"}],"termid":"GO:0031657"}


id: GO:0034548
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: N-cyclopropylammeline + H2O = N-cyclopropylammelide + NH3.","definition_xrefs":["UM-BBD_reactionID:r0826"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines","termid":"GO:0016814"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016810"}],"interesting_parent_ids":["GO:0016787","GO:0003674","GO:0003824","GO:0016810"],"is_obsolete":false,"name":"N-cyclopropylammeline deaminase activity","secondary_identifiers":["MetaCyc:RXN-8019"],"termid":"GO:0034548"}


id: PBO:0030530
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_L-aminoadipate-semialdehyde_dehydrogenase_activity","termid":"PBO:0030530"}


id: GO:1901868
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of ecgonine methyl ester.","definition_xrefs":["GOC:TermGenie","PMID:22665766"],"direct_ancestors":[{"relation_name":"is_a","term_name":"alkaloid catabolic process","termid":"GO:0009822"},{"relation_name":"is_a","term_name":"ecgonine methyl ester metabolic process","termid":"GO:1901867"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"ecgonine methyl ester catabolic process","synonyms":[{"name":"ecgonine methyl ester breakdown","type":"exact"},{"name":"ecgonine methyl ester catabolism","type":"exact"},{"name":"ecgonine methyl ester degradation","type":"exact"}],"termid":"GO:1901868"}


