# terms

id: PBO:0052401
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2","termid":"PBO:0052401"}


id: GO:0047145
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 6-demethylsterigmatocystin + S-adenosyl-L-methionine = sterigmatocystin + S-adenosyl-homocysteine.","definition_xrefs":["MetaCyc:2.1.1.109-RXN","EC:2.1.1.109"],"direct_ancestors":[{"relation_name":"is_a","term_name":"O-methyltransferase activity","termid":"GO:0008171"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016740","GO:0003674","GO:0003824","GO:0016741"],"is_obsolete":false,"name":"demethylsterigmatocystin 6-O-methyltransferase activity","secondary_identifiers":["RHEA:11504"],"synonyms":[{"name":"O-methyltransferase I","type":"related"},{"name":"S-adenosyl-L-methionine:6-demethylsterigmatocystin 6-O-methyltransferase activity","type":"related"},{"name":"demethylsterigmatocystin methyltransferase activity","type":"related"}],"termid":"GO:0047145"}


id: MONDO:0012628
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"excluded_subClassOf","term_name":"coronary artery disorder","termid":"MONDO:0005010"},{"relation_name":"is_a","term_name":"inherited disease susceptibility","termid":"MONDO:0020573"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coronary heart disease, susceptibility to, 8","secondary_identifiers":["UMLS:C1970158","MEDGEN:370192","OMIM:611139"],"synonyms":[{"name":"CHDS8","type":"exact"},{"name":"coronary heart disease, susceptibility to, 8","type":"exact"}],"termid":"MONDO:0012628","xrefs":{"Monarch":{"xref_id":"0012628"}}}


id: PBO:0072186
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S17 pseudogene 2","termid":"PBO:0072186"}


id: PBO:0049576
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"H2B.W histone 4, pseudogene","termid":"PBO:0049576"}


id: PBO:0053590
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 616","termid":"PBO:0053590"}


id: MONDO:1010674
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any thrombopathia in cattle in which the cause of the disease is a mutation in the RASGRP2 gene.","definition_xrefs":["MONDO:patterns/nonhuman_disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease, non-human animal","termid":"MONDO:1011321"},{"relation_name":"is_a","term_name":"thrombopathia, non-human animal","termid":"MONDO:1011695"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"thrombopathia, RASGRP2-related, cattle","secondary_identifiers":["OMIA:002433-9913"],"termid":"MONDO:1010674","xrefs":{"Monarch":{"xref_id":"1010674"}}}


id: GO:0031468
data:
  {"annotated_genes":["SJAG_05207","SJAG_01745","SJAG_00900","SJAG_00416","SJAG_01050","SJAG_04489","SJAG_01242","SJAG_01467","SJAG_03892","SJAG_03783","SJAG_03891"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[73854],"is_not":false,"summary":null,"term":"GO:0031468"},{"annotations":[99770,121335,93156,104967,121338,108394,97779,121336,102709,121337],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0007084"}]},"cv_name":"biological_process","definition":"The reformation of the nuclear membranes following their breakdown in the context of a normal process.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"membrane assembly","termid":"GO:0071709"},{"relation_name":"is_a","term_name":"nuclear membrane organization","termid":"GO:0071763"}],"gene_count":11,"genes_by_uniquename":{"SJAG_00416":null,"SJAG_00900":null,"SJAG_01050":null,"SJAG_01242":null,"SJAG_01467":null,"SJAG_01745":null,"SJAG_03783":null,"SJAG_03891":null,"SJAG_03892":null,"SJAG_04489":null,"SJAG_05207":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0061024"},{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0061024"}],"interesting_parent_ids":["GO:0008150","GO:0044085","GO:0061024"],"is_obsolete":false,"name":"nuclear membrane reassembly","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null,"PMID:32243490":null},"synonyms":[{"name":"nuclear envelope reassembly","type":"related"}],"termid":"GO:0031468","terms_by_termid":{"GO:0007084":null,"GO:0031468":null}}


id: PBO:0078195
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T cell receptor beta variable 5-5","termid":"PBO:0078195"}


id: GO:0015790
data:
  {"annotated_genes":["SJAG_00434"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[67601],"is_not":false,"summary":null,"term":"GO:0015790"}]},"cv_name":"biological_process","definition":"The directed movement of UDP-xylose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-xylose is a substance composed of xylose in glycosidic linkage with uridine diphosphate.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"organic anion transport","termid":"GO:0015711"},{"relation_name":"is_a","term_name":"pyrimidine nucleotide-sugar transmembrane transport","termid":"GO:0090481"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00434":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0051179","GO:0055085","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"UDP-xylose transmembrane transport","references_by_uniquename":{"GO_REF:0000108":null},"synonyms":[{"name":"UDP-xylose transport","type":"related"}],"termid":"GO:0015790","terms_by_termid":{"GO:0015790":null}}


id: PBO:0046637
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"endogenous retrovirus group W member 18","termid":"PBO:0046637"}


id: GO:0044582
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA to form butanol.","definition_xrefs":["PMID:19539744","GOC:tt","GOC:mengo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"butyryl-CoA catabolic process","termid":"GO:0044580"},{"relation_name":"is_a","term_name":"1-butanol biosynthetic process","termid":"GO:0071271"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006790"},{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0006790","GO:0008150","GO:0006629","GO:0044281","GO:0055086"],"is_obsolete":false,"name":"butyryl-CoA catabolic process to butanol","synonyms":[{"name":"butyryl-CoA catabolism to butanol","type":"exact"}],"termid":"GO:0044582"}


id: PBO:0048413
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GATA2 antisense RNA 1","termid":"PBO:0048413"}


id: GO:0070461
data:
  {"annotated_genes":["SJAG_03599","SJAG_00584","SJAG_00184","SJAG_03776","SJAG_04205","SJAG_00641","SJAG_02458","SJAG_02066","SJAG_03668","SJAG_01475","SJAG_03752","SJAG_00087","SJAG_02773","SJAG_02541","SJAG_04274","SJAG_02927","SJAG_01658","SJAG_01711","SJAG_04613"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[67721,90306,78454,78911,93220,105183,63998,73308,75535,72680,75704,62732,80622,77313,75250,113600,118142,58160,119426],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000124"},{"annotations":[58587,64000],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0046695"}]},"cv_name":"cellular_component","definition":"A histone acetyltransferase complex that acetylates nucleosomal histones H2B, H3, or H4 and is required for the expression of a subset of Pol II-transcribed genes. This complex includes the acetyltransferases GCN5/KAT2A or PCAF/KAT2B, several proteins of the ADA, SGF and SPT families, and several TBP-associate proteins (TAFs).","definition_xrefs":["PMID:10637607","GOC:mah","PMID:17337012"],"direct_ancestors":[{"relation_name":"is_a","term_name":"histone acetyltransferase complex","termid":"GO:0000123"}],"gene_count":19,"genes_by_uniquename":{"SJAG_00087":null,"SJAG_00184":null,"SJAG_00584":null,"SJAG_00641":null,"SJAG_01475":null,"SJAG_01658":null,"SJAG_01711":null,"SJAG_02066":null,"SJAG_02458":null,"SJAG_02541":null,"SJAG_02773":null,"SJAG_02927":null,"SJAG_03599":null,"SJAG_03668":null,"SJAG_03752":null,"SJAG_03776":null,"SJAG_04205":null,"SJAG_04274":null,"SJAG_04613":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005694"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0032991","GO:0005694","GO:0005575"],"is_obsolete":false,"name":"SAGA-type complex","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000104":null,"GO_REF:0000107":null},"synonyms":[{"name":"SAGA family complex","type":"exact"}],"termid":"GO:0070461","terms_by_termid":{"GO:0000124":null,"GO:0046695":null}}


id: PBO:0004447
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GRAM domain protein","termid":"PBO:0004447"}


id: MONDO:0006915
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Diseases characterized by injury or dysfunction involving multiple peripheral nerves and nerve roots. The process may primarily affect myelin or nerve axons. Two of the more common demyelinating forms are acute inflammatory polyradiculopathy (guillain-barre syndrome) and polyradiculoneuropathy, chronic inflammatory demyelinating. Polyradiculoneuritis refers to inflammation of multiple peripheral nerves and spinal nerve roots.","definition_xrefs":["MESH:D011129"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polyneuropathy","termid":"MONDO:0001824"},{"relation_name":"is_a","term_name":"demyelinating disease","termid":"MONDO:0002562"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0005559","MONDO:0005244"],"is_obsolete":false,"name":"polyradiculoneuropathy","secondary_identifiers":["DOID:4308","EFO:1001116","UMLS:C0032587","MEDGEN:46012","SCTID:128078004"],"termid":"MONDO:0006915","xrefs":{"Monarch":{"xref_id":"0006915"}}}


id: PBO:0065941
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RACK1 pseudogene 1","termid":"PBO:0065941"}


id: PBO:0041961
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"collagen and calcium binding EGF domains 1","termid":"PBO:0041961"}


id: GO:1903378
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway.","definition_xrefs":["GO_REF:0000058","GOC:PARL","GOC:TermGenie","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of neuron apoptotic process","termid":"GO:0043525"},{"relation_name":"is_a","term_name":"positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway","termid":"GO:1902177"},{"relation_name":"is_a","term_name":"regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway","termid":"GO:1903376"},{"relation_name":"positively_regulates","term_name":"neuron intrinsic apoptotic signaling pathway in response to oxidative stress","termid":"GO:0036480"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway","synonyms":[{"name":"activation of neuron apoptosis in response to oxidative stress","type":"related"},{"name":"activation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress","type":"narrow"},{"name":"positive regulation of neuron apoptosis in response to oxidative stress","type":"related"},{"name":"positive regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress","type":"exact"},{"name":"up regulation of neuron apoptosis in response to oxidative stress","type":"related"},{"name":"up regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress","type":"exact"},{"name":"up-regulation of neuron apoptosis in response to oxidative stress","type":"related"},{"name":"up-regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress","type":"exact"},{"name":"upregulation of neuron apoptosis in response to oxidative stress","type":"related"},{"name":"upregulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress","type":"exact"}],"termid":"GO:1903378"}


id: PBO:0034343
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-starts_with","termid":"PBO:0034343"}


id: GO:0046455
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of organosilicons, any organic compound that contains silicon.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"organosilicon metabolic process","termid":"GO:0018945"},{"relation_name":"is_a","term_name":"xenobiotic catabolic process","termid":"GO:0042178"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"organosilicon catabolic process","synonyms":[{"name":"organosilicon breakdown","type":"exact"},{"name":"organosilicon catabolism","type":"exact"},{"name":"organosilicon degradation","type":"exact"},{"name":"organosilicone catabolic process","type":"exact"},{"name":"organosilicone catabolism","type":"exact"}],"termid":"GO:0046455"}


id: PR:O74546
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- omh3 gene.","definition_xrefs":["UniProtKB:O74546","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"O-glycoside alpha-1,2-mannosyltransferase homolog 3 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC777.07","synonyms":[{"name":"Spom972h-omh3","type":"exact"}],"termid":"PR:O74546"}


id: PBO:0111336
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small subunit processome, U3 snoRNP-associated protein Utp7","termid":"PBO:0111336"}


id: GO:0018636
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-9,10-oxide.","definition_xrefs":["PMID:1599252","UM-BBD_reactionID:r0495"],"gene_count":0,"genotype_count":0,"name":"obsolete phenanthrene 9,10-monooxygenase activity (obsolete GO:0018636)","termid":"GO:0018636"}


id: MONDO:0013593
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any autosomal dominant nonsyndromic deafness in which the cause of the disease is a mutation in the DIABLO gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant nonsyndromic hearing loss","termid":"MONDO:0019587"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0019497"}],"interesting_parent_ids":["MONDO:0000426","MONDO:0019497"],"is_obsolete":false,"name":"autosomal dominant nonsyndromic hearing loss 64","secondary_identifiers":["GARD:18134","DOID:0110585","MEDGEN:481578","OMIM:614152","UMLS:C3279948"],"synonyms":[{"name":"DFNA64","type":"narrow"},{"name":"DIABLO autosomal dominant nonsyndromic deafness","type":"narrow"},{"name":"autosomal dominant deafness 64","type":"narrow"},{"name":"autosomal dominant nonsyndromic deafness 64","type":"narrow"},{"name":"autosomal dominant nonsyndromic deafness caused by mutation in DIABLO","type":"narrow"},{"name":"autosomal dominant nonsyndromic deafness type 64","type":"narrow"},{"name":"deafness, autosomal dominant 64","type":"narrow"},{"name":"deafness, autosomal dominant type 64","type":"narrow"}],"termid":"MONDO:0013593","xrefs":{"Monarch":{"xref_id":"0013593"}}}


id: GO:0047092
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: O2 + NADPH + 27-hydroxycholesterol = H2O + NADP+ + 7-alpha,27-dihydroxycholesterol.","definition_xrefs":["RHEA:24308"],"gene_count":0,"genotype_count":0,"name":"obsolete 27-hydroxycholesterol 7-alpha-monooxygenase activity (obsolete GO:0047092)","synonyms":[{"name":"27-hydroxycholesterol 7a-hydroxylase activity","type":"exact"},{"name":"27-hydroxycholesterol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating)","type":"exact"}],"termid":"GO:0047092"}


id: MONDO:0001467
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete specific bursitis often of occupational origin (obsolete MONDO:0001467)","secondary_identifiers":["ICD9:727.2","SCTID:42812006","DOID:12223"],"synonyms":[{"name":"specific bursitides often of occupational origin","type":"exact"}],"termid":"MONDO:0001467","xrefs":{"Monarch":{"xref_id":"0001467"}}}


id: MONDO:0005869
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete myiasis (obsolete MONDO:0005869)","termid":"MONDO:0005869","xrefs":{"Monarch":{"xref_id":"0005869"}}}


id: _global:causally_downstream_of_or_within
data:
  {"annotation_feature_type":"gene","cv_name":"external","definition":"inverse of causally upstream of or within","direct_ancestors":[{"relation_name":"is_a","term_name":"causal_relation_between_processes","termid":"_global:causal_relation_between_processes"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"causally_downstream_of_or_within","secondary_identifiers":["RO:0002427"],"termid":"_global:causally_downstream_of_or_within"}


id: PBO:0070982
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L19 pseudogene 6","termid":"PBO:0070982"}


id: GO:0036345
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A developmental process, independent of morphogenetic (shape) change, that is required for a platelet to attain its fully functional state. A platelet is a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation.","definition_xrefs":["GOC:vk","GOC:BHF","CL:0000233"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell maturation","termid":"GO:0048469"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"platelet maturation","termid":"GO:0036345"}


id: PBO:0072845
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"suppressor APC domain containing 2","termid":"PBO:0072845"}


id: PBO:0113184
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Lipid-binding ER tricalbin involved in ER-plasma membrane tethering; one of at least 7 proteins (Ice2p, Ist2p, Scs2/Scs22p, Tcb1-Tcb3p) that affect cER tethering and contact with the plasma membrane (PM); regulates PI4P levels by controlling access of the Sac1p phosphatase to its substrate PI4P in the PM; regulates PM phospholipid homeostasis; contains 3 calcium and lipid binding domains; localizes to the cortical ER and to mitochondria; C-termini of Tcb1p, Tcb2p and Tcb3p interact","termid":"PBO:0113184"}


id: PBO:0087363
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Sporulation-specific enzyme required for spore wall maturation; involved in the production of a soluble LL-dityrosine-containing precursor of the spore wall; transcripts accumulate at the time of prospore enclosure","termid":"PBO:0087363"}


id: MONDO:0012501
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete mutagen sensitivity (obsolete MONDO:0012501)","secondary_identifiers":["OMIM:610452"],"synonyms":[{"name":"mutagen sensitivity","type":"exact"}],"termid":"MONDO:0012501","xrefs":{"Monarch":{"xref_id":"0012501"}}}


id: MONDO:0003713
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"angiokeratoma","termid":"MONDO:0003143"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"angiokeratoma circumscriptum","secondary_identifiers":["MEDGEN:120485","UMLS:C0263638","NCIT:C7751","icd11.foundation:225334653","SCTID:21848000","DOID:5949"],"termid":"MONDO:0003713","xrefs":{"Monarch":{"xref_id":"0003713"}}}


id: FYPO:0000535
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which spindle pole body localization is normal (i.e. indistinguishable from wild type). Spindle pole body localization is the process in which a whole spindle pole body is transported to, or maintained in, a specific location.","definition_xrefs":["GO:0070631","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal cellular process during vegetative growth","termid":"FYPO:0001319"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001312"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0001320","FYPO:0000002","FYPO:0001312"],"is_obsolete":false,"name":"normal mitotic spindle pole body localization","synonyms":[{"name":"normal mitotic SPB localization","type":"exact"},{"name":"normal mitotic spindle pole body localisation","type":"exact"},{"name":"normal position of mitotic spindle pole body","type":"related"},{"name":"normal spindle pole body localization during mitotic cell cycle","type":"related"},{"name":"normal spindle pole body localization during vegetative growth","type":"exact"},{"name":"position of spindle pole body: normal","type":"related"}],"termid":"FYPO:0000535"}


id: GO:0046448
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving tropane alkaloids, compounds containing the 8-methyl-8-azabicyclo(3.2.1)octane ring system.","definition_xrefs":["GOC:ai","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"alkaloid metabolic process","termid":"GO:0009820"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"tropane alkaloid metabolic process","synonyms":[{"name":"tropane alkaloid metabolism","type":"exact"}],"termid":"GO:0046448"}


id: PBO:0045421
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"divergent-paired related homeobox pseudogene 1","termid":"PBO:0045421"}


id: GO:0071915
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The addition of lysine group to a lysine residue in a protein, producing N6-(lysyl)-L-lysine. This modification is observed in, and is probably unique to, translation elongation factor P (EF-P).","definition_xrefs":["GOC:jsg","PMID:20729861","GOC:imk"],"gene_count":0,"genotype_count":0,"name":"obsolete protein-lysine lysylation (obsolete GO:0071915)","synonyms":[{"name":"protein amino acid lysylation","type":"exact"}],"termid":"GO:0071915"}


id: PBO:0040793
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bone gamma-carboxyglutamate protein","termid":"PBO:0040793"}


id: PBO:0076028
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/threonine kinase 25","termid":"PBO:0076028"}


id: GO:0098613
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: S-adenosyl-L-methionine + methaneselenol => S-adenosyl-L-homocysteine + dimethyl selenide.","definition_xrefs":["PMID:4380351","PMID:14705","PMID:17988700"],"direct_ancestors":[{"relation_name":"is_a","term_name":"methyltransferase activity","termid":"GO:0008168"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016740","GO:0003674","GO:0003824","GO:0016741"],"is_obsolete":false,"name":"methaneselenol methyltransferase activity","secondary_identifiers":["Reactome:R-HSA-2408541"],"termid":"GO:0098613"}


id: MOD:01376
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-isoleucine residue to a (2S,3S,4R)-3,4-dihydroxyisoleucine.","definition_xrefs":["RESID:AA0447","ChEBI:141827","PubMed:11320328"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dihydroxylated isoleucine","termid":"MOD:01416"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"(2S,3S,4R)-3,4-dihydroxyisoleucine","synonyms":[{"name":"(2S,3S,4R)-2-amino-3,4-dihydroxy-3-methylpentanoic acid","type":"exact"},{"name":"(2S,3S,4R)-3,4-dihydroxyisoleucine","type":"exact"},{"name":"(3S,4R)-3,4-dihydroxyisoleucine","type":"exact"},{"name":"MOD_RES (3S,4R)-3,4-dihydroxyisoleucine","type":"exact"},{"name":"beta,gamma-dihydroxyisoleucine","type":"exact"}],"termid":"MOD:01376"}


id: PBO:0058214
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4506","termid":"PBO:0058214"}


id: GO:0098881
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The exocytic fusion of neurotransmitter receptor-containing vesicles with plasma membrane, resulting in the integration of neurotransmitter receptors into the plasma membrane. This process includes tethering and docking steps that prepare vesicles for fusion.","definition_xrefs":["PMID:19503082","GOC:aruk","GOC:bc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vesicle docking involved in exocytosis","termid":"GO:0006904"},{"relation_name":"is_a","term_name":"vesicle tethering involved in exocytosis","termid":"GO:0090522"},{"relation_name":"part_of","term_name":"neurotransmitter receptor transport to plasma membrane","termid":"GO:0098877"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"part_of","termid":"GO:0016192"},{"rel_name":"is_a","termid":"GO:0140056"}],"interesting_parent_ids":["GO:0008150","GO:0140056","GO:0006810","GO:0051179","GO:0016192"],"is_obsolete":false,"name":"exocytic insertion of neurotransmitter receptor to plasma membrane","synonyms":[{"name":"neurotransmitter receptor insertion","type":"exact"}],"termid":"GO:0098881"}


id: MONDO:0013470
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any generalized epilepsy with febrile seizures plus in which the cause of the disease is a mutation in the SCN9A gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"generalized epilepsy with febrile seizures plus","termid":"MONDO:0018214"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027"],"is_obsolete":false,"name":"generalized epilepsy with febrile seizures plus, type 7","secondary_identifiers":["MESH:C567827","OMIM:613863","GARD:18665","MEDGEN:416630","UMLS:C2751778","DOID:0111295"],"synonyms":[{"name":"GEFSP7","type":"related"},{"name":"Gefs+, type 7","type":"related"},{"name":"SCN9A generalised epilepsy with febrile seizures plus","type":"exact"},{"name":"SCN9A generalized epilepsy with febrile seizures plus","type":"exact"},{"name":"febrile seizures, familial, 3B","type":"related"},{"name":"generalised epilepsy with febrile seizures plus caused by mutation in SCN9A","type":"exact"},{"name":"generalized epilepsy with febrile seizures plus caused by mutation in SCN9A","type":"exact"},{"name":"generalized epilepsy with febrile seizures plus, type 7","type":"exact"}],"termid":"MONDO:0013470","xrefs":{"Monarch":{"xref_id":"0013470"}}}


id: PBO:0110234
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BouQueT formation protein","termid":"PBO:0110234"}


id: SO:1001246
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A CDS with the evidence status of being independently known.","definition_xrefs":["SO:xp"],"direct_ancestors":[{"relation_name":"has_quality","term_name":"independently_known","termid":"SO:0000906"},{"relation_name":"is_a","term_name":"CDS","termid":"SO:0000316"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CDS_independently_known","synonyms":[{"name":"CDS independently known","type":"exact"}],"termid":"SO:1001246"}


id: PBO:0085907
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein of unknown function; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern","termid":"PBO:0085907"}


id: PBO:0038281
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase sequence feature types","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"genotype_interaction","termid":"PBO:0038281"}


id: PBO:0078968
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Ser (anticodon AGA) 7-1","termid":"PBO:0078968"}


id: PBO:0111617
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CLRC complex subunit, cullin 4","termid":"PBO:0111617"}


id: PBO:0072871
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SATB1 antisense RNA 1","termid":"PBO:0072871"}


id: PBO:0081348
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 157","termid":"PBO:0081348"}


id: MONDO:0005536
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Ulcerative colitis that involves the entire colon.","direct_ancestors":[{"relation_name":"is_a","term_name":"ulcerative colitis","termid":"MONDO:0005101"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0004335"],"is_obsolete":false,"name":"pancolitis","secondary_identifiers":["UMLS:C0868908","EFO:0005626","MEDGEN:1720692","NANDO:1200450"],"synonyms":[{"name":"pan-ulcerative colitis","type":"exact"},{"name":"universal colitis","type":"exact"}],"termid":"MONDO:0005536","xrefs":{"Monarch":{"xref_id":"0005536"}}}


id: GO:0141180
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"A chromatin-protein adaptor activity that bridges dsDNA and chromatin proteins to bring regions of a chromosome in proximity. The DNA:DNA:RNA triple-helical structure is formed non-Watson-Crick base-pairing.","definition_xrefs":["PMID:35412350"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chromatin-protein adaptor activity","termid":"GO:0140463"},{"relation_name":"is_a","term_name":"sequence-specific double-stranded DNA binding","termid":"GO:1990837"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0060090"},{"rel_name":"is_a","termid":"GO:0003677"},{"rel_name":"is_a","termid":"GO:0030674"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0060090","GO:0003677","GO:0030674","GO:0005488","GO:0003674"],"is_obsolete":false,"name":"dsDNA-RNA triple helix-forming chromatin adaptor activity","termid":"GO:0141180"}


id: FYPO:0000603
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which the duration of G1 phase of a mitotic cell cycle is shorter than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal mitotic G1 phase progression","termid":"FYPO:0000602"},{"relation_name":"is_a","term_name":"decreased duration of mitotic cell cycle phase","termid":"FYPO:0001070"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000631"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0005447","FYPO:0000631","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"decreased duration of mitotic G1 phase","synonyms":[{"name":"decreased duration of G1 phase during mitotic cell cycle","type":"exact"},{"name":"decreased duration of mitotic G1 phase during vegetative growth","type":"exact"},{"name":"mitotic cell cycle progression in G1 phase: decreased duration","type":"related"},{"name":"reduced duration of mitotic G1 phase","type":"exact"}],"termid":"FYPO:0000603"}


id: MOD:01547
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces an O3-hydrogen atom of a serine residue with the Applied Biosystems iTRAQ8plex-115 reporter+balance group.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"iTRAQ8plex-115 reporter+balance reagent acylated residue","termid":"MOD:01542"},{"relation_name":"is_a","term_name":"iTRAQ8plex reporter+balance reagent O-acylated residue","termid":"MOD:01714"},{"relation_name":"is_a","term_name":"O3-acylated L-serine","termid":"MOD:02003"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"iTRAQ8plex-115 reporter+balance reagent O3-acylated serine","synonyms":[{"name":"(4-methylpiperazin-1-yl)acetyl","type":"exact"}],"termid":"MOD:01547"}


id: GO:0009713
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"catechol-containing compound metabolic process","termid":"GO:0009712"},{"relation_name":"is_a","term_name":"phenol-containing compound biosynthetic process","termid":"GO:0046189"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"catechol-containing compound biosynthetic process","synonyms":[{"name":"catechol anabolism","type":"related"},{"name":"catechol biosynthesis","type":"related"},{"name":"catechol biosynthetic process","type":"related"},{"name":"catechol formation","type":"related"},{"name":"catechol synthesis","type":"related"}],"termid":"GO:0009713"}


id: PBO:0056837
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B","termid":"PBO:0056837"}


id: GO:2001259
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of cation channel activity.","definition_xrefs":["GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of ion transmembrane transporter activity","termid":"GO:0032414"},{"relation_name":"is_a","term_name":"positive regulation of cation transmembrane transport","termid":"GO:1904064"},{"relation_name":"is_a","term_name":"regulation of cation channel activity","termid":"GO:2001257"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"positively_regulates","termid":"GO:0055085"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0008150","GO:0055085"],"is_obsolete":false,"name":"positive regulation of cation channel activity","synonyms":[{"name":"positive regulation of cation diffusion facilitator activity","type":"exact"},{"name":"positive regulation of nonselective cation channel activity","type":"exact"}],"termid":"GO:2001259"}


id: PBO:0042852
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CFAP61 antisense RNA 1","termid":"PBO:0042852"}


id: SO:0002142
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A histone 2A modification where the modification is the acetylation of the residue.","definition_xrefs":["ISBN:0815341059"],"direct_ancestors":[{"relation_name":"is_a","term_name":"histone_acetylation_site","termid":"SO:0001702"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"SO:0000839"}],"interesting_parent_ids":["SO:0000839"],"is_obsolete":false,"name":"histone_2A_acetylation_site","synonyms":[{"name":"H2Aac","type":"exact"},{"name":"histone 2A acetylation site","type":"exact"}],"termid":"SO:0002142"}


id: PBO:0059457
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"minisatellite binding protein 1","termid":"PBO:0059457"}


id: PBO:0001213
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ornithine cyclodeaminase family (predicted)","termid":"PBO:0001213"}


id: PBO:0038285
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase feature property types","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"molecular_weight","termid":"PBO:0038285"}


id: PBO:0040350
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP synthase membrane subunit g","termid":"PBO:0040350"}


id: PATO:0001165
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0001165 urine enzyme composition value (obsolete PATO:0001165)","termid":"PATO:0001165"}


id: MONDO:0006084
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete angioleiomyoma (obsolete MONDO:0006084)","termid":"MONDO:0006084","xrefs":{"Monarch":{"xref_id":"0006084"}}}


id: GO:0004883
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"A nuclear receptor activity regulated by glucocorticoid binding and modulating the transcription of specific gene sets transcribed by RNA polymerase II.","definition_xrefs":["PMID:17689856","GOC:signaling","PMID:20920967"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nuclear steroid receptor activity","termid":"GO:0003707"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140110"},{"rel_name":"is_a","termid":"GO:0003700"},{"rel_name":"is_a","termid":"GO:0038023"}],"interesting_parent_ids":["GO:0038023","GO:0003674","GO:0003700","GO:0140110"],"is_obsolete":false,"name":"nuclear glucocorticoid receptor activity","synonyms":[{"name":"glucocorticoid receptor activity","type":"broad"}],"termid":"GO:0004883"}


id: GO:0033659
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which an organism effects a change in the structure or function of host cell mitochondria. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:pamgo_curators","PMID:35069483","PMID:37175745"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated disruption of host cellular anatomical structure","termid":"GO:0052008"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"symbiont-mediated disruption of host mitochondrion","synonyms":[{"name":"disruption by symbiont of host mitochondrion","type":"exact"},{"name":"modification by symbiont of host mitochondrion","type":"related"}],"termid":"GO:0033659"}


id: PBO:0056567
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mucolipin TRP cation channel 2","termid":"PBO:0056567"}


id: PBO:0031322
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_menadione","termid":"PBO:0031322"}


id: GO:0075720
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as a distinct genetic entity.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"establishment of viral latency","termid":"GO:0019043"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"establishment of episomal latency","synonyms":[{"name":"establishment as a plasmid prophage","type":"narrow"},{"name":"establishment of plasmid latency","type":"exact"}],"termid":"GO:0075720"}


id: FYPO:0007835
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which histone binding by a gene product (usually a protein) in a mutant occurs to a greater extent than normal. The affected protein may be encoded by the mutated gene, or by a different gene.","definition_xrefs":["PomBase:mah","PMID:31837996"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased protein-protein interaction","termid":"FYPO:0001571"},{"relation_name":"is_a","term_name":"abnormal histone binding","termid":"FYPO:0007157"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000702"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000652","FYPO:0000707","FYPO:0001985","FYPO:0000702"],"is_obsolete":false,"name":"increased histone binding","synonyms":[{"name":"increased protein-histone interaction","type":"exact"}],"termid":"FYPO:0007835"}


id: MONDO:0017474
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"disorder of development or morphogenesis","termid":"MONDO:0021147"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"macrodactyly of fingers","secondary_identifiers":["MEDGEN:107892","SCTID:297195000","Orphanet:295044","GARD:8529","HP:0100746","UMLS:C0574044","MESH:C537720","icd11.foundation:1647254435"],"synonyms":[{"name":"Megalodactyly of the hand","type":"related"},{"name":"macrodactyly of hand","type":"exact"},{"name":"macrodactyly of the hand","type":"related"},{"name":"megalodactylism of the hand","type":"related"}],"termid":"MONDO:0017474","xrefs":{"Monarch":{"xref_id":"0017474"}}}


id: PATO:0001388
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A disomy quality inhering in a bearer by virtue of the bearer's containing two copies of the chromosome from one of the parents (with no contribution from the other parent).","definition_xrefs":["Wikipedia:http://en.wikipedia.org/wiki/Uniparental_disomy"],"direct_ancestors":[{"relation_name":"is_a","term_name":"disomy","termid":"PATO:0001387"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uniparental disomy","termid":"PATO:0001388"}


id: GO:1905540
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that binds interleukin-7 (IL-7) and that consists of, at a minimum, an interleukin, an alpha and a gamma chain as well as optional additional kinase subunits. The alpha chain binds IL-7 with high affinity and subsequently binds the cytokine receptor common gamma chain that forms part of multiple interleukin receptors.","definition_xrefs":["GOC:bhm","GO_REF:0000088","GOC:TermGenie","PMID:19141282"],"direct_ancestors":[{"relation_name":"is_a","term_name":"receptor complex","termid":"GO:0043235"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"interleukin-7 receptor complex","synonyms":[{"name":"IL-7 receptor complex","type":"exact"},{"name":"IL-7-receptor complex","type":"exact"},{"name":"IL7 receptor complex","type":"exact"},{"name":"IL7-receptor complex","type":"exact"}],"termid":"GO:1905540"}


id: PBO:0053978
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1290","termid":"PBO:0053978"}


id: PBO:0052387
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"KIF26A divergent transcript","termid":"PBO:0052387"}


id: PBO:0085493
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Proposed gamma subunit of the heterotrimeric G protein; interacts with the receptor Gpr1p; involved in regulation of pseudohyphal growth; requires Gpb1p or Gpb2p to interact with Gpa2p; overproduction causes prion curing","termid":"PBO:0085493"}


id: RO:0002360
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","direct_ancestors":[{"relation_name":"is_a","term_name":"overlaps","termid":"RO:0002131"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"has_dendrite_location","termid":"RO:0002360"}


id: GO:0018140
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl cysteine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.","definition_xrefs":["RESID:AA0244"],"gene_count":0,"genotype_count":0,"name":"obsolete peptide cross-linking via L-cysteine thiazolecarboxylic acid (obsolete GO:0018140)","termid":"GO:0018140"}


id: PBO:0089882
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial matrix import factor Mix23","termid":"PBO:0089882"}


id: PR:O59835
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A DNA polymerase delta subunit 4 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR14303:SF0","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA polymerase delta subunit 4 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC12D12.02c","secondary_identifiers":["UniProtKB:O59835"],"synonyms":[{"name":"SPBC12D12.02c","type":"related"},{"name":"Spom972h-POLD4","type":"exact"}],"termid":"PR:O59835"}


id: PBO:0078601
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tripartite motif containing 60 pseudogene 14","termid":"PBO:0078601"}


id: MONDO:0009039
data:
  {"annotated_genes":["SJAG_04995","SJAG_02200"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87322,87323],"is_not":false,"summary":null,"term":"MONDO:0009039"}]},"cv_name":"mondo","definition":"Baller-Gerold syndrome is characterized by the association of coronal craniosynostosis with radial ray anomalies (oligodactyly, aplasia or hypoplasia of the thumb, aplasia or hypoplasia of the radius).","definition_xrefs":["Orphanet:1225"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic craniosynostosis","termid":"MONDO:0015338"}],"gene_count":2,"genes_by_uniquename":{"SJAG_02200":null,"SJAG_04995":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"Baller-Gerold syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C0265308","MEDGEN:120532","OMIM:218600","icd11.foundation:1650688177","DOID:0050654","MESH:C536788","GARD:1602","NANDO:1201059","NORD:834","SCTID:77608001"],"synonyms":[{"name":"BALLER-Gerold syndrome","type":"related"},{"name":"BGS","type":"related"},{"name":"Baller-Gerold syndrome","type":"exact"},{"name":"craniosynostosis with radial defects","type":"related"},{"name":"craniosynostosis-radial aplasia syndrome","type":"related"}],"termid":"MONDO:0009039","terms_by_termid":{"MONDO:0009039":null},"xrefs":{"Monarch":{"xref_id":"0009039"}}}


id: PBO:0087524
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of ISW2/yCHRAC chromatin accessibility complex; ISW2/yCHRAC also includes Itc1p, Isw2p, and Dpb4p; involved in inheritance of telomeric silencing; DLS1 has a paralog, DPB3, that arose from the whole genome duplication","termid":"PBO:0087524"}


id: FYPO:0007370
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell population phenotype in which a cell population in the vegetative growth phase of the life cycle grows at a faster rate than normal in a medium containing fructose as the carbon source.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased cell population growth rate","termid":"FYPO:0000636"},{"relation_name":"is_a","term_name":"increased cell population growth on fructose carbon source","termid":"FYPO:0009095"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0000139"}],"interesting_parent_ids":["FYPO:0002058","FYPO:0000139","FYPO:0000003","FYPO:0002057","FYPO:0005447","FYPO:0001985"],"is_obsolete":false,"name":"increased cell population growth rate on fructose carbon source","synonyms":[{"name":"enhanced growth on fructose","type":"related"},{"name":"fast cell population growth on fructose carbon source","type":"exact"},{"name":"increased cell population proliferation on fructose carbon source","type":"related"},{"name":"increased cell proliferation on fructose carbon source","type":"related"},{"name":"increased vegetative cell population growth rate on fructose carbon source","type":"exact"}],"termid":"FYPO:0007370"}


id: PBO:0074205
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SLC39A13 antisense RNA 1","termid":"PBO:0074205"}


id: MONDO:0700063
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A disease characteristic in which the cause of the disease is present in all the cells of the organism.","direct_ancestors":[{"relation_name":"is_a","term_name":"mosaic vs complete","termid":"MONDO:0700061"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"complete","termid":"MONDO:0700063","xrefs":{"Monarch":{"xref_id":"0700063"}}}


id: PBO:0038433
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acetoacetyl-CoA synthetase pseudogene 1","termid":"PBO:0038433"}


id: MONDO:1012009
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"renal amyloidosis, non-human animal","termid":"MONDO:1011903"},{"relation_name":"is_a","term_name":"renal disease, dog","termid":"MONDO:1012235"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"renal amyloidosis, dog","secondary_identifiers":["OMIA:000040-9615"],"termid":"MONDO:1012009","xrefs":{"Monarch":{"xref_id":"1012009"}}}


id: GO:0098558
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The side (leaflet) of the smooth endoplasmic reticulum membrane that faces the lumen.","definition_xrefs":["GOC:dos","GOC:ab"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lumenal side of endoplasmic reticulum membrane","termid":"GO:0098553"},{"relation_name":"part_of","term_name":"smooth endoplasmic reticulum membrane","termid":"GO:0030868"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005783"},{"rel_name":"part_of","termid":"GO:0005789"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0005737","GO:0005789","GO:0005575","GO:0005783"],"is_obsolete":false,"name":"lumenal side of smooth endoplasmic reticulum membrane","termid":"GO:0098558"}


id: PBO:0069199
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 453, pseudogene","termid":"PBO:0069199"}


id: GO:1903176
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of tyrosine 3-monooxygenase activity.","definition_xrefs":["GOC:TermGenie","GO_REF:0000059","GOC:bf","GOC:PARL"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of tyrosine 3-monooxygenase activity (obsolete GO:1903176)","synonyms":[{"name":"regulation of L-tyrosine hydroxylase activity","type":"exact"},{"name":"regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)","type":"exact"},{"name":"regulation of tyrosine 3-hydroxylase activity","type":"exact"},{"name":"regulation of tyrosine hydroxylase activity","type":"exact"}],"termid":"GO:1903176"}


id: PBO:0031510
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_mitotic_cell_cycle_arrest_in_response_to_nitrogen_starvation","termid":"PBO:0031510"}


id: PBO:0074333
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1","termid":"PBO:0074333"}


id: PBO:0005719
data:
  {"annotation_feature_type":"gene","cv_name":"disease_associated","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hereditary leiomyomatosis","termid":"PBO:0005719"}


id: GO:0075332
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:pamgo_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete modulation by host of symbiont adenylate cyclase-mediated signal transduction (obsolete GO:0075332)","termid":"GO:0075332"}


id: GO:1905059
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"A calcium-transporting P-type ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration.","definition_xrefs":["GOC:TermGenie","GO_REF:0000061","PMID:20678993"],"direct_ancestors":[{"relation_name":"is_a","term_name":"P-type calcium transporter activity","termid":"GO:0005388"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0003674","GO:0022857","GO:0005215"],"is_obsolete":false,"name":"P-type calcium transporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration","synonyms":[{"name":"ATP phosphohydrolase (Ca2+-transporting) involved in regulation of postsynaptic cytosolic calcium ion concentration","type":"exact"},{"name":"ATPase-coupled calcium ion transmembrane transporter activity involved in regulation of postsynaptic cytosolic calcium levels","type":"exact"},{"name":"Ca(2+)-transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration","type":"exact"},{"name":"Ca2+-pumping ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration","type":"exact"},{"name":"Ca2+-transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration","type":"exact"},{"name":"calcium ABC transporter involved in regulation of postsynaptic cytosolic calcium ion concentration","type":"narrow"},{"name":"calcium efflux ATPase involved in regulation of postsynaptic cytosolic calcium ion concentration","type":"narrow"},{"name":"calcium transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration","type":"exact"},{"name":"calcium-translocating P-type ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration","type":"narrow"},{"name":"calcium-transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration","type":"exact"},{"name":"calcium-transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium levels","type":"exact"},{"name":"plasma membrane Ca-ATPase involved in regulation of postsynaptic cytosolic calcium ion concentration","type":"narrow"},{"name":"sarco(endo)plasmic reticulum Ca2+-ATPase involved in regulation of postsynaptic cytosolic calcium ion concentration","type":"narrow"},{"name":"sarcoplasmic reticulum ATPase involved in regulation of postsynaptic cytosolic calcium ion concentration","type":"narrow"}],"termid":"GO:1905059"}


id: PBO:0071551
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L35a pseudogene 16","termid":"PBO:0071551"}


id: GO:0045135
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: polysaccharides containing beta-D-mannuronate residues = oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl end. This reaction is the eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends.","definition_xrefs":["EC:4.2.2.3"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbon-oxygen lyase activity, acting on polysaccharides","termid":"GO:0016837"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016829","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"poly(beta-D-mannuronate) lyase activity","secondary_identifiers":["MetaCyc:4.2.2.3-RXN"],"synonyms":[{"name":"alginase I","type":"related"},{"name":"alginase activity","type":"related"},{"name":"alginate lyase I activity","type":"narrow"},{"name":"alginate lyase activity","type":"related"},{"name":"poly(beta-D-1,4-mannuronide) lyase activity","type":"related"},{"name":"poly(mana) alginate lyase activity","type":"narrow"}],"termid":"GO:0045135"}


id: GO:1905668
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of protein localization to endosome.","definition_xrefs":["PMID:22732145","GOC:TermGenie","GO_REF:0000058","GOC:bc","GOC:PARL"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of protein localization","termid":"GO:1903829"},{"relation_name":"is_a","term_name":"regulation of protein localization to endosome","termid":"GO:1905666"},{"relation_name":"positively_regulates","term_name":"protein localization to endosome","termid":"GO:0036010"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of protein localization to endosome","synonyms":[{"name":"activation of protein localisation in endosome","type":"narrow"},{"name":"activation of protein localization in endosome","type":"narrow"},{"name":"activation of protein localization to endosome","type":"narrow"},{"name":"positive regulation of protein localisation in endosome","type":"exact"},{"name":"positive regulation of protein localization in endosome","type":"exact"},{"name":"up regulation of protein localisation in endosome","type":"exact"},{"name":"up regulation of protein localization in endosome","type":"exact"},{"name":"up regulation of protein localization to endosome","type":"exact"},{"name":"up-regulation of protein localisation in endosome","type":"exact"},{"name":"up-regulation of protein localization in endosome","type":"exact"},{"name":"up-regulation of protein localization to endosome","type":"exact"},{"name":"upregulation of protein localisation in endosome","type":"exact"},{"name":"upregulation of protein localization in endosome","type":"exact"},{"name":"upregulation of protein localization to endosome","type":"exact"}],"termid":"GO:1905668"}


id: GO:0006707
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cholesterol metabolic process","termid":"GO:0008203"},{"relation_name":"is_a","term_name":"sterol catabolic process","termid":"GO:0016127"},{"relation_name":"is_a","term_name":"alcohol catabolic process","termid":"GO:0046164"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0006629","GO:0008150"],"is_obsolete":false,"name":"cholesterol catabolic process","synonyms":[{"name":"cholesterol breakdown","type":"exact"},{"name":"cholesterol catabolism","type":"exact"},{"name":"cholesterol degradation","type":"exact"}],"termid":"GO:0006707"}


id: MONDO:0043723
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Fracture in the proximal half of the shaft of the ulna, with dislocation of the head of the radius.","definition_xrefs":["MESH:D009011"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ulna fracture","termid":"MONDO:0005322"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Monteggia's fracture","secondary_identifiers":["SCTID:123973009"],"synonyms":[{"name":"Monteggia fracture","type":"related"},{"name":"Monteggias fracture","type":"related"},{"name":"fracture, Monteggia's","type":"related"},{"name":"monteggia fracture","type":"related"},{"name":"monteggia fracture dislocation","type":"related"},{"name":"monteggia's dislocation","type":"related"},{"name":"monteggia's fracture","type":"exact"}],"termid":"MONDO:0043723","xrefs":{"Monarch":{"xref_id":"0043723"}}}


id: MONDO:0000563
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant cerebellar ataxia","termid":"MONDO:0020380"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0002039"}],"interesting_parent_ids":["MONDO:0002039","MONDO:0005559","MONDO:0000426"],"is_obsolete":false,"name":"GRID2-related autosomal dominant spinocerebellar ataxia","secondary_identifiers":["DOID:0050988"],"synonyms":[{"name":"GRID2-related spinocerebellar ataxia","type":"related"}],"termid":"MONDO:0000563","xrefs":{"Monarch":{"xref_id":"0000563"}}}


id: MONDO:0009472
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acetylation, slow","secondary_identifiers":["MEDGEN:164207","OMIM:243400","UMLS:C0878587"],"synonyms":[{"name":"Fast acetylator phenotype","type":"related"},{"name":"INH inactivation, Fast","type":"related"},{"name":"INH inactivation, slow","type":"related"},{"name":"Isoniazid inactivation, slow","type":"related"},{"name":"acetylation, Fast","type":"related"},{"name":"acetylation, slow","type":"exact"},{"name":"slow acetylator phenotype","type":"related"}],"termid":"MONDO:0009472","xrefs":{"Monarch":{"xref_id":"0009472"}}}


id: GO:0002447
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process involved in the carrying out of an immune response by an eosinophil.","definition_xrefs":["GO_REF:0000022","ISBN:0781735149","GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myeloid leukocyte mediated immunity","termid":"GO:0002444"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"eosinophil mediated immunity","termid":"GO:0002447"}


id: GO:0000741
data:
  {"annotated_genes":["SJAG_04936","SJAG_00810","SJAG_02737","SJAG_01370","SJAG_01613","SJAG_02286","SJAG_02045"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[80387,101033,113318,118809,92806,93198,89573],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000742"},{"annotations":[80389],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0048288"}]},"cv_name":"biological_process","definition":"The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei.","definition_xrefs":["GOC:elh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleus organization","termid":"GO:0006997"},{"relation_name":"is_a","term_name":"organelle fusion","termid":"GO:0048284"},{"relation_name":"part_of","term_name":"nucleus organization","termid":"GO:0006997"}],"gene_count":7,"genes_by_uniquename":{"SJAG_00810":null,"SJAG_01370":null,"SJAG_01613":null,"SJAG_02045":null,"SJAG_02286":null,"SJAG_02737":null,"SJAG_04936":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"karyogamy","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["GO:0007335","Wikipedia:Karyogamy"],"synonyms":[{"name":"nuclear fusion","type":"exact"},{"name":"nuclear fusion during karyogamy","type":"exact"}],"termid":"GO:0000741","terms_by_termid":{"GO:0000742":null,"GO:0048288":null}}


id: MONDO:0031376
data:
  {"annotated_genes":["SJAG_03227"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86791],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0800044"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"inborn errors of metabolism","termid":"MONDO:0019052"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03227":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066"],"is_obsolete":false,"name":"congenital disorder of deglycosylation","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIMPS:615273","MEDGEN:815321","UMLS:C3808991"],"termid":"MONDO:0031376","terms_by_termid":{"MONDO:0800044":null},"xrefs":{"Monarch":{"xref_id":"0031376"}}}


id: SO:0001995
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A sequence variant occurring in the intron, within 10 bases of exon.","definition_xrefs":["sanger:am"],"direct_ancestors":[{"relation_name":"is_a","term_name":"splicing_variant","termid":"SO:0001568"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"extended_intronic_splice_region_variant","synonyms":[{"name":"extended intronic splice region variant","type":"exact"}],"termid":"SO:0001995"}


id: PR:O94339
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mug96 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O94339"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiotically up-regulated gene 96 protein (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC1271.06c","synonyms":[{"name":"Spom972h-mug96","type":"exact"}],"termid":"PR:O94339"}


id: PBO:0026913
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_duration_of_actomyosin_contractile_ring_contraction","termid":"PBO:0026913"}


id: GO:0031536
data:
  {"annotated_genes":["SJAG_01801","SJAG_00082","SJAG_03126","SJAG_03048"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[91812,95563,104193,113815],"is_not":false,"summary":null,"term":"GO:0031536"}]},"cv_name":"biological_process","definition":"Any process that activates or increases the rate of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity).","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of exit from mitosis","termid":"GO:0007096"},{"relation_name":"is_a","term_name":"positive regulation of mitotic cell cycle phase transition","termid":"GO:1901992"},{"relation_name":"positively_regulates","term_name":"exit from mitosis","termid":"GO:0010458"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00082":null,"SJAG_01801":null,"SJAG_03048":null,"SJAG_03126":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0044772"},{"rel_name":"regulates","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0044772"},{"rel_name":"positively_regulates","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0007049","GO:0008150","GO:0044772"],"is_obsolete":false,"name":"positive regulation of exit from mitosis","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"activation of exit from mitosis","type":"narrow"},{"name":"stimulation of exit from mitosis","type":"narrow"},{"name":"up regulation of exit from mitosis","type":"exact"},{"name":"up-regulation of exit from mitosis","type":"exact"},{"name":"upregulation of exit from mitosis","type":"exact"}],"termid":"GO:0031536","terms_by_termid":{"GO:0031536":null}}


id: GO:0047837
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: D-xylose + NADP+ = D-xylono-1,5-lactone + H+ + NADPH.","definition_xrefs":["RHEA:22000"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"D-xylose 1-dehydrogenase (NADP+) activity","secondary_identifiers":["EC:1.1.1.179","MetaCyc:D-XYLOSE-1-DEHYDROGENASE-NADP+-RXN","KEGG_REACTION:R01430"],"synonyms":[{"name":"D-xylose (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity","type":"related"},{"name":"D-xylose-NADP dehydrogenase activity","type":"related"},{"name":"D-xylose:NADP+ 1-oxidoreductase activity","type":"related"},{"name":"D-xylose:NADP+ oxidoreductase activity","type":"related"}],"termid":"GO:0047837"}


id: PBO:0070133
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U7 small nuclear 47 pseudogene","termid":"PBO:0070133"}


id: MONDO:0800031
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"central hypoventilation syndrome, congenital","secondary_identifiers":["OMIMPS:209880","UMLS:C1275808","MEDGEN:220902"],"termid":"MONDO:0800031","xrefs":{"Monarch":{"xref_id":"0800031"}}}


id: PBO:0082975
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cytoplasmic thioredoxin isoenzyme; part of the thioredoxin system that protects cells from oxidative and reductive stress; subunit of the LMA1 complex, with Pbi2p, that promotes vacuole inheritance; cofactor for Tsa1p; required for ER-Golgi transport; facilitates mitochondrial import of small Tims (Tim9p, Tim10p, Tim13p) by maintaining them in reduced form along with Trx1p; component of a signal transduction redox relay in a light sensing pathway; abundance increases under DNA replication stress","termid":"PBO:0082975"}


id: GO:0008174
data:
  {"annotated_genes":["SJAG_04034","SJAG_02099","SJAG_00325"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[95740,92270],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0062152"},{"annotations":[74084],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004482"}]},"cv_name":"molecular_function","definition":"Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an mRNA molecule.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA methyltransferase activity","termid":"GO:0008173"},{"relation_name":"is_a","term_name":"S-adenosylmethionine-dependent methyltransferase activity","termid":"GO:0008757"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00325":null,"SJAG_02099":null,"SJAG_04034":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0140098","GO:0016741","GO:0016740","GO:0003824"],"is_obsolete":false,"name":"mRNA methyltransferase activity","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0008174","terms_by_termid":{"GO:0004482":null,"GO:0062152":null}}


id: PBO:0048402
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GAS6 divergent transcript","termid":"PBO:0048402"}


id: MONDO:0021475
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign neoplasm that involves the nasal cavity.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"respiratory system benign neoplasm","termid":"MONDO:0000382"},{"relation_name":"is_a","term_name":"sensory organ benign neoplasm","termid":"MONDO:0000633"},{"relation_name":"is_a","term_name":"nasal cavity neoplasm","termid":"MONDO:0004756"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"benign neoplasm of nasal cavity","secondary_identifiers":["ICD9:212.0","MEDGEN:83859","icd11.foundation:44101401","NCIT:C4603","SCTID:92241005","UMLS:C0347215"],"synonyms":[{"name":"benign nasal cavity neoplasm","type":"exact"},{"name":"benign nasal cavity tumor","type":"exact"},{"name":"benign nasal cavity tumour","type":"exact"},{"name":"benign neoplasm of the nasal cavity","type":"exact"},{"name":"benign tumor of nasal cavity","type":"exact"},{"name":"benign tumor of the nasal cavity","type":"exact"},{"name":"benign tumour of nasal cavity","type":"exact"},{"name":"benign tumour of the nasal cavity","type":"exact"},{"name":"nasal cavity benign neoplasm","type":"exact"}],"termid":"MONDO:0021475","xrefs":{"Monarch":{"xref_id":"0021475"}}}


id: PBO:0042281
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CD1a molecule","termid":"PBO:0042281"}


id: MONDO:0010182
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary hypercarotenemia and vitamin A deficiency","termid":"MONDO:0007272"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066"],"is_obsolete":false,"name":"hypercarotenemia and vitamin A deficiency, autosomal recessive","secondary_identifiers":["MEDGEN:395578","GARD:18302","MESH:C567486","UMLS:C2678266","OMIM:277350"],"synonyms":[{"name":"hypercarotenemia and vitamin A deficiency, autosomal recessive","type":"exact"}],"termid":"MONDO:0010182","xrefs":{"Monarch":{"xref_id":"0010182"}}}


id: PR:P26359
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- msh3 gene.","definition_xrefs":["PRO:DNx","UniProtKB:P26359"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA mismatch repair protein msh3 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC8F11.03","synonyms":[{"name":"MutS protein homolog 3 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-msh3","type":"exact"},{"name":"mating-type switching protein swi4 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:P26359"}


id: MONDO:0035892
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare, acquired motor neuron disease characterized by a slowly progressive, unilateral, ascending or descending hemplegia, associated to unilateral or asymmetrical pyramidal signs and no sensory loss. It is a diagnosis of exclusion and contorversy exists regarding whether the presence of bulbar symptoms, sphincter disturbances, fasciculations or cognitive manifestations characterize the disease.","definition_xrefs":["Orphanet:94091"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acquired motor neuron disease","termid":"MONDO:0020129"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"Mills syndrome","secondary_identifiers":["MEDGEN:1682801","GARD:19250","UMLS:C5191669"],"termid":"MONDO:0035892","xrefs":{"Monarch":{"xref_id":"0035892"}}}


id: GO:0097377
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the migration of an axon growth cone of a spinal cord interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal cord interneuron is a CNS interneuron located in the spinal cord.","definition_xrefs":["CL:0005000","GOC:pr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"interneuron axon guidance","termid":"GO:0097376"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"spinal cord interneuron axon guidance","termid":"GO:0097377"}


id: MONDO:0013563
data:
  {"annotated_genes":["SJAG_04165"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87748],"is_not":false,"summary":null,"term":"MONDO:0013563"}]},"cv_name":"mondo","definition":"Any multiple congenital anomalies/dysmorphic syndrome-intellectual disability in which the cause of the disease is a mutation in the PIGN gene.","definition_xrefs":["MONDO:design_pattern"],"direct_ancestors":[{"relation_name":"is_a","term_name":"developmental anomaly of metabolic origin","termid":"MONDO:0015327"},{"relation_name":"is_a","term_name":"inborn disorder of glycosphingolipid and glycosylphosphatidylinositol anchor glycosylation","termid":"MONDO:0017748"},{"relation_name":"is_a","term_name":"multiple congenital anomalies-hypotonia-seizures syndrome","termid":"MONDO:0100247"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04165":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0024322"},{"rel_name":"is_a","termid":"MONDO:0002525"}],"interesting_parent_ids":["MONDO:0024322","MONDO:0005066","MONDO:0002525"],"is_obsolete":false,"name":"multiple congenital anomalies-hypotonia-seizures syndrome 1","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["NCIT:C176896","GARD:12781","MEDGEN:481405","Orphanet:280633","OMIM:614080","UMLS:C3279775","DOID:0080138"],"synonyms":[{"name":"MCAHS1","type":"related"},{"name":"PIGN multiple congenital anomalies/dysmorphic syndrome-intellectual disability","type":"exact"},{"name":"PIGN-CDG","type":"exact"},{"name":"PIGN-related inherited GPI deficiency","type":"narrow"},{"name":"congenital disorder of glycosylation due to PIGN deficiency","type":"exact"},{"name":"glycosylphosphatidylinositol biosynthesis defect 3","type":"related"},{"name":"inherited GPI anchor-deficiency","type":"exact"},{"name":"multiple congenital anomalies - hypotonia - seizures syndrome","type":"related"},{"name":"multiple congenital anomalies-hypotonia-seizures syndrome","type":"related"},{"name":"multiple congenital anomalies-hypotonia-seizures syndrome 1","type":"exact"},{"name":"multiple congenital anomalies-hypotonia-seizures syndrome type 1","type":"exact"},{"name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability caused by mutation in PIGN","type":"exact"}],"termid":"MONDO:0013563","terms_by_termid":{"MONDO:0013563":null},"xrefs":{"Monarch":{"xref_id":"0013563"}}}


id: GO:0001958
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Replacement ossification wherein bone tissue replaces cartilage.","definition_xrefs":["GO_REF:0000034","ISBN:0878932437"],"direct_ancestors":[{"relation_name":"is_a","term_name":"replacement ossification","termid":"GO:0036075"},{"relation_name":"part_of","term_name":"endochondral bone morphogenesis","termid":"GO:0060350"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"endochondral ossification","secondary_identifiers":["Wikipedia:Endochondral_ossification"],"termid":"GO:0001958"}


id: PBO:0063864
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"piezo type mechanosensitive ion channel component 2","termid":"PBO:0063864"}


id: PBO:0028630
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_U6_2'-O-snRNA_methylation_at_residue_A41","termid":"PBO:0028630"}


id: GO:0090503
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways involving the hydrolysis of terminal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides.","definition_xrefs":["GOC:dph","GOC:tb"],"gene_count":0,"genotype_count":0,"name":"obsolete RNA phosphodiester bond hydrolysis, exonucleolytic (obsolete GO:0090503)","termid":"GO:0090503"}


id: GO:0075012
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:pamgo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of developmental process","termid":"GO:0051093"},{"relation_name":"is_a","term_name":"regulation of germ tube formation","termid":"GO:0075010"},{"relation_name":"negatively_regulates","term_name":"germ tube formation","termid":"GO:0075009"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of germ tube formation","synonyms":[{"name":"negative regulation of germ tube formation on or near host","type":"exact"}],"termid":"GO:0075012"}


id: FYPO:0003728
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the galactosylation of one or more specific proteins, or of specific protein sites, does not occur. Protein galactosylation is the addition of a galactose residue to a protein amino acid.","definition_xrefs":["PomBase:mah","GO:0042125"],"direct_ancestors":[{"relation_name":"has_output","term_name":"galactose absent from glycoprotein glycan","termid":"FYPO:0003291"},{"relation_name":"is_a","term_name":"abnormal protein glycosylation during vegetative growth","termid":"FYPO:0001910"},{"relation_name":"is_a","term_name":"abolished cellular process","termid":"FYPO:0005449"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0005447","FYPO:0000002","FYPO:0002494","FYPO:0001320","FYPO:0002274"],"is_obsolete":false,"name":"abolished protein galactosylation during vegetative growth","synonyms":[{"name":"abolished protein galactosylation during mitotic cell cycle","type":"related"},{"name":"protein galactosylation abolished during vegetative growth","type":"exact"}],"termid":"FYPO:0003728"}


id: FYPO:0007274
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which mitochondrion inheritance is abnormal. Mitochondrion inheritance is a cellular process that results in the distribution of mitochondria into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton.","definition_xrefs":["PomBase:mah","GO:0000001"],"direct_ancestors":[{"relation_name":"is_a","term_name":"localization phenotype","termid":"FYPO:0000138"},{"relation_name":"is_a","term_name":"abnormal cellular component organization","termid":"FYPO:0000335"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001985","FYPO:0000002","FYPO:0000138"],"is_obsolete":false,"name":"abnormal mitochondrion inheritance","synonyms":[{"name":"abnormal mitochondrial inheritance","type":"exact"}],"termid":"FYPO:0007274"}


id: GO:0033889
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the hydrolysis of the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-sulfate units of heparin.","definition_xrefs":["EC:3.1.6.15"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sulfuric ester hydrolase activity","termid":"GO:0008484"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016788"}],"interesting_parent_ids":["GO:0016787","GO:0003674","GO:0003824","GO:0016788"],"is_obsolete":false,"name":"N-sulfoglucosamine-3-sulfatase activity","secondary_identifiers":["MetaCyc:3.1.6.15-RXN"],"synonyms":[{"name":"N-sulfo-3-sulfoglucosamine 3-sulfohydrolase activity","type":"related"},{"name":"chondroitinsulfatase activity","type":"broad"}],"termid":"GO:0033889"}


id: GO:0048834
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the number of petals formed in a flower.","definition_xrefs":["GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"specification of floral organ number","termid":"GO:0048833"},{"relation_name":"part_of","term_name":"corolla development","termid":"GO:0048465"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"specification of petal number","termid":"GO:0048834"}


id: PBO:0081169
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger FYVE-type containing 1","termid":"PBO:0081169"}


id: PBO:0066451
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"REXO1 like 3, pseudogene","termid":"PBO:0066451"}


id: PBO:0083081
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Divalent metal ion transporter; broad specificity for di-valent and tri-valent metals; post-translationally regulated by levels of metal ions; member of the Nramp family of metal transport proteins","termid":"PBO:0083081"}


id: RO:0002093
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","direct_ancestors":[{"relation_name":"is_a","term_name":"temporally_related_to","termid":"RO:0002222"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ends_during","termid":"RO:0002093"}


id: PBO:0081159
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ZFPM2 antisense RNA 1","termid":"PBO:0081159"}


id: MONDO:0007854
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Keratolytic winter erythema is a rare epidermal disease, characterized by recurrent centrifugal palmoplantar peeling and erythema presenting seasonal variation (cold weather). Skin lesions may spread to the dorsum of hands and feet and to the interdigital spaces. Lower legs, knees and thighs may also be involved. Episodes may be preceded by itch and hyperhidrosis. Skin biopsy reveals an epidermal spongiosis with clefting in the stratum corneum, followed by regrowth. Keratolytic winter erythema follows an autosomal dominant mode of transmission.","definition_xrefs":["Orphanet:50943"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epidermal disease","termid":"MONDO:0019268"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"keratolytic winter erythema","secondary_identifiers":["SCTID:239064000","UMLS:C0406756","ICD9:695.89","MEDGEN:98359","OMIM:148370","MESH:C536155","GARD:8275","NORD:1286","icd11.foundation:1491245207"],"synonyms":[{"name":"Erythrokeratolysis hiemalis","type":"exact"},{"name":"Erythrokeratolysis hiemalis ichthyosis","type":"related"},{"name":"KWE","type":"related"},{"name":"Oudtshoorn disease","type":"exact"},{"name":"Oudtshoorn skin","type":"related"},{"name":"Oudtshoorn skin disease","type":"related"},{"name":"keratolytic WINTER erythema","type":"related"},{"name":"keratolytic winter erythema","type":"exact"}],"termid":"MONDO:0007854","xrefs":{"Monarch":{"xref_id":"0007854"}}}


id: GO:1901492
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of lymphangiogenesis.","definition_xrefs":["PMID:20133819","GOC:dph","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of developmental process","termid":"GO:0051094"},{"relation_name":"is_a","term_name":"regulation of lymphangiogenesis","termid":"GO:1901490"},{"relation_name":"positively_regulates","term_name":"lymphangiogenesis","termid":"GO:0001946"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of lymphangiogenesis","synonyms":[{"name":"activation of lymph vessel formation","type":"narrow"},{"name":"activation of lymphangiogenesis","type":"narrow"},{"name":"positive regulation of lymph vessel formation","type":"exact"},{"name":"up regulation of lymph vessel formation","type":"exact"},{"name":"up regulation of lymphangiogenesis","type":"exact"},{"name":"up-regulation of lymph vessel formation","type":"exact"},{"name":"up-regulation of lymphangiogenesis","type":"exact"},{"name":"upregulation of lymph vessel formation","type":"exact"},{"name":"upregulation of lymphangiogenesis","type":"exact"}],"termid":"GO:1901492"}


id: GO:0016426
data:
  {"annotated_genes":["SJAG_02637","SJAG_02386"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[114004,62838],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0160107"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methyladenine.","definition_xrefs":["GOC:go-curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tRNA methyltransferase activity","termid":"GO:0008175"},{"relation_name":"is_a","term_name":"S-adenosylmethionine-dependent methyltransferase activity","termid":"GO:0008757"}],"gene_count":2,"genes_by_uniquename":{"SJAG_02386":null,"SJAG_02637":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0140101"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016741"}],"interesting_parent_ids":["GO:0016741","GO:0016740","GO:0140101","GO:0003674","GO:0003824","GO:0140098"],"is_obsolete":false,"name":"tRNA (adenine) methyltransferase activity","references_by_uniquename":{"GO_REF:0000003":null,"GO_REF:0000107":null},"synonyms":[{"name":"tRNA (adenine-C2-)-methyltransferase activity","type":"broad"}],"termid":"GO:0016426","terms_by_termid":{"GO:0160107":null}}


id: GO:0075271
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a fruiting body called zygosporangium is formed. A zygosporangium is a thick-walled structure in which spores are produced, and is characteristic of the Zygomycetes.","definition_xrefs":["GOC:pamgo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"spore-bearing structure development","termid":"GO:0075259"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"zygosporangium development","termid":"GO:0075271"}


id: GO:0002028
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of metal ion transport","termid":"GO:0010959"},{"relation_name":"regulates","term_name":"sodium ion transport","termid":"GO:0006814"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0006810"],"is_obsolete":false,"name":"regulation of sodium ion transport","synonyms":[{"name":"regulation of Na+ transport","type":"exact"},{"name":"regulation of sodium transport","type":"exact"}],"termid":"GO:0002028"}


id: GO:0097102
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process involved in the specification of identity of an endothelial tip cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial tip cell is a specialized endothelial cell localized to the leading edge of an angiogenic sprout that senses extracellular signals and guides the directed growth of blood vessels.","definition_xrefs":["GOC:dgh","PMID:21521739","CL:0000704"],"direct_ancestors":[{"relation_name":"is_a","term_name":"blood vessel endothelial cell fate specification","termid":"GO:0097101"},{"relation_name":"part_of","term_name":"sprouting angiogenesis","termid":"GO:0002040"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"endothelial tip cell fate specification","synonyms":[{"name":"angiogenic tip cell fate specification","type":"exact"}],"termid":"GO:0097102"}


id: PBO:0061591
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"neurotrophic receptor tyrosine kinase 2","termid":"PBO:0061591"}


id: MONDO:0005205
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete systemic lupus erythematosus (obsolete MONDO:0005205)","termid":"MONDO:0005205","xrefs":{"Monarch":{"xref_id":"0005205"}}}


id: GO:0090156
data:
  {"annotated_genes":["SJAG_04550"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[74837],"is_not":false,"summary":null,"term":"GO:0090156"}]},"cv_name":"biological_process","definition":"A homeostatic process involved in the maintenance of a steady state level of sphingolipids within a cell.","definition_xrefs":["GOC:ascb_2009","GOC:tb","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracellular chemical homeostasis","termid":"GO:0055082"},{"relation_name":"is_a","term_name":"lipid homeostasis","termid":"GO:0055088"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04550":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"intracellular sphingolipid homeostasis","references_by_uniquename":{"GO_REF:0000033":null},"synonyms":[{"name":"cellular sphingolipid homeostasis","type":"exact"}],"termid":"GO:0090156","terms_by_termid":{"GO:0090156":null}}


id: GO:1990814
data:
  {"annotated_genes":["SJAG_03682","SJAG_03780","SJAG_03832","SJAG_00871"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[105004,114385,115248,117776],"is_not":false,"summary":null,"term":"GO:1990814"}]},"cv_name":"molecular_function","definition":"An activity that facilitates the formation of a complementary double-stranded DNA molecule.","definition_xrefs":["PMID:25520186","PMID:22888405"],"direct_ancestors":[{"relation_name":"is_a","term_name":"single-stranded DNA binding","termid":"GO:0003697"},{"relation_name":"is_a","term_name":"catalytic activity, acting on DNA","termid":"GO:0140097"},{"relation_name":"is_a","term_name":"annealing activity","termid":"GO:0140666"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00871":null,"SJAG_03682":null,"SJAG_03780":null,"SJAG_03832":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140097"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016853"},{"rel_name":"is_a","termid":"GO:0003677"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016853","GO:0140097","GO:0003824","GO:0003677","GO:0003674","GO:0005488"],"is_obsolete":false,"name":"DNA/DNA annealing activity","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"DNA reannealing activity","type":"exact"}],"termid":"GO:1990814","terms_by_termid":{"GO:1990814":null}}


id: GO:0060092
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.","definition_xrefs":["GOC:dms","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modulation of chemical synaptic transmission","termid":"GO:0050804"},{"relation_name":"regulates","term_name":"synaptic transmission, glycinergic","termid":"GO:0060012"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"regulation of synaptic transmission, glycinergic","termid":"GO:0060092"}


id: PBO:0050731
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heat shock protein family D (Hsp60) member 1 pseudogene 17","termid":"PBO:0050731"}


id: GO:0042203
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products.","definition_xrefs":["UM-BBD_pathwayID:tol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"toluene metabolic process","termid":"GO:0018970"},{"relation_name":"is_a","term_name":"xenobiotic catabolic process","termid":"GO:0042178"},{"relation_name":"is_a","term_name":"toluene-containing compound catabolic process","termid":"GO:0072491"},{"relation_name":"is_a","term_name":"hydrocarbon catabolic process","termid":"GO:0120253"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"toluene catabolic process","synonyms":[{"name":"toluene breakdown","type":"exact"},{"name":"toluene catabolism","type":"exact"},{"name":"toluene degradation","type":"exact"}],"termid":"GO:0042203"}


id: PBO:0058738
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 6862-2","termid":"PBO:0058738"}


id: MONDO:0006683
data:
  {"annotated_genes":["SJAG_00663"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87948],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008076"}]},"cv_name":"mondo","definition":"A brachial plexus disorder characterized by regional paresthesia, pain and muscle weakness, and limited movement in the arm or hand.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nerve plexus disorder","termid":"MONDO:0024432"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00663":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0005244"],"is_obsolete":false,"name":"brachial plexus neuropathy","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["NCIT:C27194","MESH:D020516","EFO:1000844","DOID:3690","ICD9:353.0","SCTID:3548001","UMLS:C0700251","MEDGEN:148580"],"synonyms":[{"name":"brachial nerve plexus peripheral neuropathy","type":"exact"},{"name":"brachial plexopathy","type":"exact"},{"name":"brachial plexus disorder","type":"exact"},{"name":"peripheral neuropathy of brachial nerve plexus","type":"exact"}],"termid":"MONDO:0006683","terms_by_termid":{"MONDO:0008076":null},"xrefs":{"Monarch":{"xref_id":"0006683"}}}


id: PBO:0058916
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 12135","termid":"PBO:0058916"}


id: PBO:0054437
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1833","termid":"PBO:0054437"}


id: PBO:0005808
data:
  {"annotation_feature_type":"gene","cv_name":"misc","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"the chromatin assembly function of H2Bub is independent of H3K4 methylation","termid":"PBO:0005808"}


id: PBO:0043862
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"carnitine O-acetyltransferase","termid":"PBO:0043862"}


id: PBO:0031515
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_protein_binding","termid":"PBO:0031515"}


id: PBO:0027826
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_uracil_DNA_N-glycosylase_activity","termid":"PBO:0027826"}


id: PBO:0046353
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ectonucleotide pyrophosphatase/phosphodiesterase 7 pseudogene 11","termid":"PBO:0046353"}


id: PBO:0077937
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TPTEP2-CSNK1E readthrough","termid":"PBO:0077937"}


id: MONDO:1040042
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any ciliopathy caused by variants in the BBS7 gene.","definition_xrefs":["PMID:19797195"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ciliopathy","termid":"MONDO:0005308"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BBS7-related ciliopathy","synonyms":[{"name":"BBS7-related ciliopathy","type":"exact"}],"termid":"MONDO:1040042","xrefs":{"Monarch":{"xref_id":"1040042"}}}


id: PBO:0055881
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leucine rich repeat containing 7","termid":"PBO:0055881"}


id: PBO:0004779
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial GrpE domain chaperone protein (predicted)","termid":"PBO:0004779"}


id: PBO:0030867
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_cytokinesis","termid":"PBO:0030867"}


id: PBO:0087528
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of NuA4, an essential histone acetyltransferase complex; positions Piccolo NuA4 for efficient acetylation of histone H4 or histone H2A; relocalizes to the cytosol in response to hypoxia; similar to human tumor suppressor ING1 and its isoforms ING4 and ING5","termid":"PBO:0087528"}


id: MONDO:0000107
data:
  {"annotated_genes":["SJAG_00321"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88092],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013845"},{"annotations":[88148],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0957544"}]},"cv_name":"mondo","definition":"Auriculo-condylar syndrome (ACS) presents with bilateral external ear malformations ('question mark' ears), mandibular condyle hypoplasia, microstomia, micrognathia, microglossia and facial asymmetry. Additional manifestations include hypotonia, ptosis, cleft palate, puffy cheeks, developmental delay, impaired hearing and respiratory distress.","definition_xrefs":["Orphanet:137888"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"craniofacial microsomia","termid":"MONDO:0015397"},{"relation_name":"is_a","term_name":"ear malformation","termid":"MONDO:0007500"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00321":null},"genotype_count":0,"is_obsolete":false,"name":"auriculocondylar syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C1865295","MESH:C538270","SCTID:702443003","OMIMPS:602483","MEDGEN:355953","GARD:9798"],"synonyms":[{"name":"auriculo-condylar syndrome","type":"exact"},{"name":"dysgnathia complex","type":"related"},{"name":"ears prominent and constricted","type":"related"},{"name":"question mark ear","type":"related"},{"name":"question mark ear syndrome","type":"exact"},{"name":"question-mark ear syndrome","type":"related"}],"termid":"MONDO:0000107","terms_by_termid":{"MONDO:0013845":null,"MONDO:0957544":null},"xrefs":{"Monarch":{"xref_id":"0000107"}}}


id: GO:0045174
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: dehydroascorbate + 2 glutathione = L-ascorbate + glutathione disulfide.","definition_xrefs":["RHEA:24424"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glutathione disulfide oxidoreductase activity","termid":"GO:0015038"},{"relation_name":"is_a","term_name":"antioxidant activity","termid":"GO:0016209"},{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor","termid":"GO:0016672"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0015036"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003824","GO:0015036","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"glutathione dehydrogenase (ascorbate) activity","secondary_identifiers":["MetaCyc:1.8.5.1-RXN","KEGG_REACTION:R01108","Reactome:R-HSA-198813","EC:1.8.5.1"],"synonyms":[{"name":"DHA reductase activity","type":"related"},{"name":"GDOR","type":"related"},{"name":"dehydroascorbate reductase activity","type":"exact"},{"name":"dehydroascorbic acid reductase activity","type":"related"},{"name":"dehydroascorbic reductase activity","type":"related"},{"name":"glutathione dehydroascorbate reductase activity","type":"related"},{"name":"glutathione:dehydroascorbate oxidoreductase activity","type":"related"},{"name":"glutathione:dehydroascorbic acid oxidoreductase activity","type":"related"}],"termid":"GO:0045174"}


id: GO:1990566
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"An inward rectifier potassium channel complex expressed in cardiac muscle, specifically the sinoatrial node and atria, where it controls the heart rate, via regulation by G protein-coupled receptor signaling. In mammals it is composed of GIRK1 (or Kir3.1) and GIRK4 (or Kir3.4) subunits.","definition_xrefs":["GOC:ame","PMID:9765280"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inward rectifier potassium channel complex","termid":"GO:1902937"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005886"}],"interesting_parent_ids":["GO:0005575","GO:0005886","GO:0032991"],"is_obsolete":false,"name":"I(KACh) inward rectifier potassium channel complex","synonyms":[{"name":"GIRK1-GIRK4 G protein-coupled atrial inward rectifier potassium channel complex","type":"related"},{"name":"Kir3.1-Kir3.4 G protein-coupled atrial inward rectifier potassium channel complex","type":"related"},{"name":"muscarinic potassium channel complex","type":"related"}],"termid":"GO:1990566"}


id: MONDO:0015500
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Facial arteriovenous malformation is a rare vascular anomaly characterized by abnormal communication between arteries and veins, bypassing the capillary bed, located in the facial area. Lesions may be asymptomatic or may manifest with pain, ulceration, pulsation, tinnitus, minor bleeding or potentially life-threatening hemorrhage, blurred vision, impaired hearing, headache, paresthesia, enlargement of facial bones with intraosseous lesions, intraosseous hemangiomas, and speech, breathing and swallowing difficulties, as well as neuropathy.","definition_xrefs":["Orphanet:156230"],"direct_ancestors":[{"relation_name":"is_a","term_name":"arteriovenous hemangioma/malformation","termid":"MONDO:0001256"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"facial arteriovenous malformation","secondary_identifiers":["GARD:12663","UMLS:C5680665","MEDGEN:1842762","icd11.foundation:926860967"],"termid":"MONDO:0015500","xrefs":{"Monarch":{"xref_id":"0015500"}}}


id: GO:0002603
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II","termid":"GO:0002582"},{"relation_name":"is_a","term_name":"regulation of antigen processing and presentation of polysaccharide antigen via MHC class II","termid":"GO:0002601"},{"relation_name":"positively_regulates","term_name":"antigen processing and presentation of polysaccharide antigen via MHC class II","termid":"GO:0002505"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of antigen processing and presentation of polysaccharide antigen via MHC class II","synonyms":[{"name":"activation of antigen processing and presentation of polysaccharide antigen via MHC class II","type":"narrow"},{"name":"positive regulation of polysaccharide antigen processing and presentation via MHC class II","type":"exact"},{"name":"stimulation of antigen processing and presentation of polysaccharide antigen via MHC class II","type":"narrow"},{"name":"up regulation of antigen processing and presentation of polysaccharide antigen via MHC class II","type":"exact"},{"name":"up-regulation of antigen processing and presentation of polysaccharide antigen via MHC class II","type":"exact"},{"name":"upregulation of antigen processing and presentation of polysaccharide antigen via MHC class II","type":"exact"}],"termid":"GO:0002603"}


id: PBO:0027942
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_protein_localization_to_chromatin_at_RNA_polymerase_II-regulated_genes_during_vegetative_growth","termid":"PBO:0027942"}


id: MONDO:0004598
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A form of acute right heart failure produced by a sudden increase in resistance to blood flow in the pulmonary circulation.","definition_xrefs":["PMID:19186411"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cor pulmonale","termid":"MONDO:0004596"},{"relation_name":"is_a","term_name":"acute disease","termid":"MONDO:0020683"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"acute cor pulmonale","secondary_identifiers":["DOID:8517","MEDGEN:510041","SCTID:67189007","UMLS:C0155671","ICD9:415","SCTID:49584005","DOID:8514","ICD9:415.0"],"synonyms":[{"name":"acute pulmonary heart disease","type":"exact"},{"name":"cor pulmonale, acute","type":"exact"}],"termid":"MONDO:0004598","xrefs":{"Monarch":{"xref_id":"0004598"}}}


id: MONDO:1010026
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Budd-Chiari syndrome that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cardiovascular disorder, non-human animal","termid":"MONDO:1011306"},{"relation_name":"is_a","term_name":"liver disorder, non-human animal","termid":"MONDO:1012967"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Budd-Chiari syndrome, non-human animal","secondary_identifiers":["OMIA:001203"],"termid":"MONDO:1010026","xrefs":{"Monarch":{"xref_id":"1010026"}}}


id: PBO:0061667
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NUP50 divergent transcript","termid":"PBO:0061667"}


id: PBO:0089973
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA polymerase II associated Paf1 complex subunit Leo1","termid":"PBO:0089973"}


id: GO:0060701
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that decreases the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.","definition_xrefs":["GOC:tb","GOC:dph"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of ribonuclease activity (obsolete GO:0060701)","termid":"GO:0060701"}


id: GO:0035240
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to dopamine, a catecholamine neurotransmitter formed by aromatic-L-amino-acid decarboxylase from 3,4-dihydroxy-L-phenylalanine.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cation binding","termid":"GO:0043169"},{"relation_name":"is_a","term_name":"catecholamine binding","termid":"GO:1901338"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0003674","GO:0005488"],"is_obsolete":false,"name":"dopamine binding","termid":"GO:0035240"}


id: GO:0030295
data:
  {"annotated_genes":["SJAG_03371","SJAG_01401","SJAG_00318","SJAG_04020","SJAG_03699","SJAG_04502","SJAG_04666","SJAG_03936","SJAG_05017","SJAG_03090","SJAG_00236","SJAG_00333","SJAG_02232","SJAG_02785","SJAG_00439","SJAG_03453","SJAG_03618","SJAG_04200","SJAG_01213","SJAG_00457","SJAG_00142","SJAG_04140","SJAG_00424","SJAG_03695","SJAG_04509","SJAG_01411","SJAG_02026","SJAG_01605","SJAG_02605","SJAG_02332","SJAG_02057","SJAG_04614","SJAG_03340"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[71892,72200,74019,74660,80182,91035,93122,101006,108977,113290,114338,118179],"is_not":false,"summary":null,"term":"GO:0030295"},{"annotations":[118939,103444,75812,67367,72004,113057,81565,114824],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061575"},{"annotations":[91049,93002,112396,91257,77202,77197,94244,106955,92669,89721,111116,120248,70560],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0043539"}]},"cv_name":"molecular_function","definition":"Binds to and increases the activity of a protein kinase, an enzyme which phosphorylates a protein.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"kinase activator activity","termid":"GO:0019209"},{"relation_name":"is_a","term_name":"protein kinase regulator activity","termid":"GO:0019887"}],"gene_count":33,"genes_by_uniquename":{"SJAG_00142":null,"SJAG_00236":null,"SJAG_00318":null,"SJAG_00333":null,"SJAG_00424":null,"SJAG_00439":null,"SJAG_00457":null,"SJAG_01213":null,"SJAG_01401":null,"SJAG_01411":null,"SJAG_01605":null,"SJAG_02026":null,"SJAG_02057":null,"SJAG_02232":null,"SJAG_02332":null,"SJAG_02605":null,"SJAG_02785":null,"SJAG_03090":null,"SJAG_03340":null,"SJAG_03371":null,"SJAG_03453":null,"SJAG_03618":null,"SJAG_03695":null,"SJAG_03699":null,"SJAG_03936":null,"SJAG_04020":null,"SJAG_04140":null,"SJAG_04200":null,"SJAG_04502":null,"SJAG_04509":null,"SJAG_04614":null,"SJAG_04666":null,"SJAG_05017":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0098772"},{"rel_name":"is_a","termid":"GO:0030234"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140677"}],"interesting_parent_ids":["GO:0140677","GO:0030234","GO:0098772","GO:0003674"],"is_obsolete":false,"name":"protein kinase activator activity","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0030295","terms_by_termid":{"GO:0030295":null,"GO:0043539":null,"GO:0061575":null}}


id: PBO:0062913
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"P2RX5-TAX1BP3 readthrough (NMD candidate)","termid":"PBO:0062913"}


id: MONDO:0018159
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"atypical hemolytic-uremic syndrome","termid":"MONDO:0016244"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005570"],"is_obsolete":false,"name":"atypical hemolytic-uremic syndrome with DGKE deficiency","secondary_identifiers":["Orphanet:357008","MEDGEN:1826167","UMLS:C5679921","GARD:17543"],"synonyms":[{"name":"AHUS with DGKE deficiency","type":"exact"},{"name":"D-HUS with DGKE deficiency","type":"exact"},{"name":"atypical HUS with DGKE deficiency","type":"exact"},{"name":"hemolytic-uremic syndrome without diarrhea with DGKE deficiency","type":"exact"},{"name":"hemolytic-uremic syndrome without diarrhoea with DGKE deficiency","type":"exact"}],"termid":"MONDO:0018159","xrefs":{"Monarch":{"xref_id":"0018159"}}}


id: PBO:0031247
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_regulation_of_pseudohyphal_growth","termid":"PBO:0031247"}


id: GO:0103063
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: ATP(4-) + H2O + a trans-keto-C61-meroacyl-[acp] = diphosphoric acid + a trans-keto-meroacyl-adenylate + a holo-[acyl-carrier protein].","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete trans-keto-C61-meroacyl-AMP ligase activity (obsolete GO:0103063)","termid":"GO:0103063"}


id: PBO:0002342
data:
  {"annotation_feature_type":"gene","cv_name":"sequence_feature","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein vacuolar sorting signal","termid":"PBO:0002342"}


id: MONDO:0020015
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. A rare form of cardiovascular disease.","gene_count":0,"genotype_count":0,"name":"obsolete rare circulatory system disease (obsolete MONDO:0020015)","secondary_identifiers":["Orphanet:98028"],"synonyms":[{"name":"rare cardiovascular disease","type":"exact"}],"termid":"MONDO:0020015","xrefs":{"Monarch":{"xref_id":"0020015"}}}


id: GO:0050983
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions resulting in the formation of deoxyhypusine from spermidine by the enzyme [eIF-5A]-deoxyhypusine synthase. The reaction occurs in four steps: 1. spermidine + NAD+ = dehydrospermidine + NADH + H+; 2. dehydrospermidine + [enzyme]-lysine = 1,3-diaminopropane + [enzyme]-lysine-N6=CH(CH2)3NH2; 3. [enzyme]-lysine-N6=CH(CH2)3NH2 = [eIF-5A]-lysine-N6=CH(CH2)3NH2; 4. [eIF-5A]-lysine-N6=CH(CH2)3NH2 + NADH + H+ = [eIF-5A]-deoxyhypusine + NAD+.","definition_xrefs":["MetaCyc:1.1.1.249-RXN"],"gene_count":0,"genotype_count":0,"name":"obsolete deoxyhypusine biosynthetic process from spermidine (obsolete GO:0050983)","synonyms":[{"name":"deoxyhypusine anabolism from spermidine, using deoxyhypusine synthase","type":"exact"},{"name":"deoxyhypusine biosynthesis from spermidine, using deoxyhypusine synthase","type":"exact"},{"name":"deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase","type":"exact"},{"name":"deoxyhypusine formation from spermidine, using deoxyhypusine synthase","type":"exact"},{"name":"spermidine breakdown to deoxyhypusine, using deoxyhypusine synthase","type":"exact"},{"name":"spermidine catabolic process to deoxyhypusine, using deoxyhypusine synthase","type":"exact"},{"name":"spermidine degradation to deoxyhypusine, using deoxyhypusine synthase","type":"exact"}],"termid":"GO:0050983"}


id: GO:2000869
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of estrone secretion.","definition_xrefs":["GOC:sl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of steroid hormone secretion","termid":"GO:2000833"},{"relation_name":"is_a","term_name":"regulation of estrone secretion","termid":"GO:2000867"},{"relation_name":"positively_regulates","term_name":"estrone secretion","termid":"GO:0035943"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"positively_regulates","termid":"GO:0023052"},{"rel_name":"positively_regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0023052","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"positive regulation of estrone secretion","synonyms":[{"name":"positive regulation of 3-hydroxy-1,3,5(10)-estratrien-17-one secretion","type":"exact"},{"name":"positive regulation of folliculin secretion","type":"exact"}],"termid":"GO:2000869"}


id: PBO:0069288
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 544, pseudogene","termid":"PBO:0069288"}


id: PR:O13835
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A U3 small nucleolar ribonucleoprotein protein IMP3 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO02165","PANTHER:PTHR11831:SF1"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"U3 small nucleolar ribonucleoprotein protein imp3 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC19D5.05c","secondary_identifiers":["UniProtKB:O13835"],"synonyms":[{"name":"Spom972h-IMP3","type":"exact"},{"name":"U3 snoRNP protein imp3 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O13835"}


id: GO:0002849
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of peripheral T cell tolerance induction.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of peripheral tolerance induction","termid":"GO:0002658"},{"relation_name":"is_a","term_name":"regulation of T cell tolerance induction","termid":"GO:0002664"},{"relation_name":"is_a","term_name":"regulation of T cell mediated immunity","termid":"GO:0002709"},{"relation_name":"regulates","term_name":"peripheral T cell tolerance induction","termid":"GO:0002458"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of peripheral T cell tolerance induction","termid":"GO:0002849"}


id: MONDO:0004985
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A disorder of the brain that causes unusual shifts in mood, energy, activity levels and the ability to carry out day-to-day tasks. Often these moods range and shift from periods of elation and energized behavior to those of hopelessness and depression.","definition_xrefs":["NCIT:C34423"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mood disorder","termid":"MONDO:0005371"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bipolar disorder","secondary_identifiers":["ICD9:296.40","MESH:D001714","DOID:3312","SCTID:13746004","birnlex:12754","ICD9:296.80","ICD10WHO:F31","UMLS:C0005586","MEDGEN:2649","ICD10CM:F31","ICD9:296.89","ICD9:296.60"],"synonyms":[{"name":"MAFD","type":"related"},{"name":"bipolar affective disorder","type":"related"},{"name":"bipolar depression","type":"narrow"},{"name":"bipolar disorder","type":"exact"},{"name":"bipolar disorder manic phase","type":"narrow"},{"name":"depressive-manic psych.","type":"related"},{"name":"major affective disorder","type":"exact"},{"name":"major bipolar affective disorder","type":"related"},{"name":"manic bipolar I disorder","type":"narrow"},{"name":"manic bipolar affective disorder","type":"narrow"},{"name":"manic depression","type":"narrow"},{"name":"manic depressive disorder","type":"narrow"},{"name":"manic disorder","type":"narrow"},{"name":"manic-depression","type":"exact"},{"name":"manic-depressive illness","type":"related"},{"name":"manic-depressive psychosis","type":"related"},{"name":"mixed bipolar disorder","type":"narrow"}],"termid":"MONDO:0004985","xrefs":{"Monarch":{"xref_id":"0004985"}}}


id: GO:0043713
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2-oxoisocaproate + NADH + H+ = (R)-2-hydroxyisocaproate + NAD+.","definition_xrefs":["GOC:jl","PMID:16957230"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"(R)-2-hydroxyisocaproate dehydrogenase activity","termid":"GO:0043713"}


id: PBO:0068400
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ring finger protein 217","termid":"PBO:0068400"}


id: PBO:0056948
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 15b","termid":"PBO:0056948"}


id: MONDO:0006786
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A condition in which the hepatic venous outflow is obstructed anywhere from the small hepatic veins to the junction of the inferior vena cava and the right atrium. Usually the blockage is extrahepatic and caused by blood clots (thrombus) or fibrous webs. Parenchymal fibrosis is uncommon.","definition_xrefs":["MESH:D006502"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hepatic vascular disorder","termid":"MONDO:0002405"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002515"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0002515","MONDO:0004335"],"is_obsolete":false,"name":"hepatic vein thrombosis","secondary_identifiers":["UMLS:C0019154","EFO:1000966","SCTID:38739001","SCTID:82385007","MedDRA:10006537","ICD10CM:I82.0","MEDGEN:9217","icd11.foundation:2131410813","ICD9:453.0","MedDRA:10019713","DOID:11512"],"synonyms":[{"name":"Budd-Chiari syndrome","type":"related"},{"name":"hepatic vein thrombosis","type":"exact"}],"termid":"MONDO:0006786","xrefs":{"Monarch":{"xref_id":"0006786"}}}


id: PBO:0071370
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L29 pseudogene 29","termid":"PBO:0071370"}


id: PBO:0041953
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coiled-coil and C2 domain containing 1A","termid":"PBO:0041953"}


id: MONDO:0700190
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A malignant lymphoma that arises in the bursa of Fabricius in a chicken.","definition_xrefs":["NCIT:C134556"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chicken lymphoma","termid":"MONDO:0700194"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chicken bursal lymphoma","termid":"MONDO:0700190","xrefs":{"Monarch":{"xref_id":"0700190"}}}


id: MONDO:0004097
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete lipid-rich breast carcinoma (obsolete MONDO:0004097)","termid":"MONDO:0004097","xrefs":{"Monarch":{"xref_id":"0004097"}}}


id: PBO:0004222
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"N-end-recognizing protein Ubr1","termid":"PBO:0004222"}


id: PBO:0083310
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps ORF ARG5,6/YER069W","termid":"PBO:0083310"}


id: PBO:0073053
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SCY1 like pseudokinase 1","termid":"PBO:0073053"}


id: GO:1904430
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of t-circle formation.","definition_xrefs":["GOC:TermGenie","GOC:BHF_telomere","GOC:BHF","PMID:22579284","GO_REF:0000058","GOC:nc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of DNA metabolic process","termid":"GO:0051053"},{"relation_name":"is_a","term_name":"negative regulation of cellular component organization","termid":"GO:0051129"},{"relation_name":"is_a","term_name":"regulation of t-circle formation","termid":"GO:1904429"},{"relation_name":"negatively_regulates","term_name":"t-circle formation","termid":"GO:0090656"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0006259"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0032200"},{"rel_name":"regulates","termid":"GO:0044085"},{"rel_name":"regulates","termid":"GO:0006259"}],"interesting_parent_ids":["GO:0006259","GO:0008150","GO:0044085","GO:0032200"],"is_obsolete":false,"name":"negative regulation of t-circle formation","synonyms":[{"name":"down regulation of t-circle formation","type":"exact"},{"name":"down regulation of telomeric circle formation","type":"exact"},{"name":"down-regulation of t-circle formation","type":"exact"},{"name":"down-regulation of telomeric circle formation","type":"exact"},{"name":"downregulation of t-circle formation","type":"exact"},{"name":"downregulation of telomeric circle formation","type":"exact"},{"name":"inhibition of t-circle formation","type":"narrow"},{"name":"inhibition of telomeric circle formation","type":"narrow"},{"name":"negative regulation of telomeric circle formation","type":"exact"}],"termid":"GO:1904430"}


id: PBO:0024814
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-capable_of_regulating","termid":"PBO:0024814"}


id: PBO:0042413
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cell division cycle 25C","termid":"PBO:0042413"}


id: MONDO:0032627
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"mitochondrial complex I deficiency, nuclear type","termid":"MONDO:0100223"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004069"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0004069"],"is_obsolete":false,"name":"mitochondrial complex 1 deficiency, nuclear type 23","secondary_identifiers":["GARD:18374","MEDGEN:1648408","DOID:0112087","UMLS:C4748799","OMIM:618244"],"synonyms":[{"name":"MC1DN23","type":"related"},{"name":"MITOCHONDRIAL COMPLEX I DEFICIENCY, NUCLEAR TYPE 23","type":"related"}],"termid":"MONDO:0032627","xrefs":{"Monarch":{"xref_id":"0032627"}}}


id: PBO:0086354
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Purine-cytosine permease; mediates purine (adenine, guanine, and hypoxanthine) and cytosine accumulation; relative distribution to the vacuole increases upon DNA replication stress","termid":"PBO:0086354"}


id: FYPO:0004473
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which a spore germinates to produce a cell that enters the cell cycle but then undergoes cell cycle arrest with unreplicated DNA, and eventually dies.","definition_xrefs":["PMID:9356477","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal mitotic cell cycle arrest with unreplicated DNA","termid":"FYPO:0001430"},{"relation_name":"is_a","term_name":"inviable after spore germination, without cell division, cell cycle arrest","termid":"FYPO:0001924"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000004"},{"rel_name":"has_part","termid":"FYPO:0005447"},{"rel_name":"has_part","termid":"FYPO:0000631"},{"rel_name":"has_part","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0001320","FYPO:0000002","FYPO:0000004","FYPO:0005447","FYPO:0000631"],"is_obsolete":false,"name":"inviable after spore germination, without cell division, cell cycle arrest with unreplicated DNA","synonyms":[{"name":"inviable following spore germination, without cell division, cell cycle arrest with unreplicated DNA","type":"exact"},{"name":"inviable germinated spore, without cell division, cell cycle arrest with unreplicated DNA","type":"exact"},{"name":"lethal after spore germination, without cell division, cell cycle arrest with unreplicated DNA","type":"exact"}],"termid":"FYPO:0004473"}


id: PBO:0061978
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 2 subfamily AS member 1 pseudogene","termid":"PBO:0061978"}


id: MONDO:0010127
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An instance of thymoma (disease) that is caused by an inherited modification of the individual's genome.","definition_xrefs":["MONDO:patterns/hereditary"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"thymoma","termid":"MONDO:0006456"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005570"],"is_obsolete":false,"name":"thymoma, familial","secondary_identifiers":["MEDGEN:376447","MESH:C564767","UMLS:C1848814","OMIM:274230"],"synonyms":[{"name":"hereditary thymoma (disease)","type":"exact"},{"name":"thymic neoplasia","type":"related"},{"name":"thymoma, familial","type":"exact"}],"termid":"MONDO:0010127","xrefs":{"Monarch":{"xref_id":"0010127"}}}


id: FYPO:0002489
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"An inviable phenotype in which a spore lyses, i.e. the plasma membrane ruptures and cytoplasm is lost. Note that in fission yeast cell lysis, the integrity of the cell wall is also compromised.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"has_part","term_name":"inviable spore","termid":"FYPO:0002151"},{"relation_name":"is_a","term_name":"inviable spore","termid":"FYPO:0002151"},{"relation_name":"is_a","term_name":"cell lysis","termid":"FYPO:0002488"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000004"},{"rel_name":"has_part","termid":"FYPO:0000004"}],"interesting_parent_ids":["FYPO:0000004","FYPO:0000002"],"is_obsolete":false,"name":"spore lysis","synonyms":[{"name":"inviable, lysed spore","type":"exact"},{"name":"spore cytolysis","type":"exact"}],"termid":"FYPO:0002489"}


id: PBO:0046538
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"endogenous retrovirus group E member 1","termid":"PBO:0046538"}


id: PBO:0081680
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 601, pseudogene","termid":"PBO:0081680"}


id: PBO:0116844
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene characterisation status","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"biological_role_published","termid":"PBO:0116844"}


id: MOD:01511
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces an O3-hydrogen atom of a serine residue with the Applied Biosystems iTRAQ4plex-117 reporter+balance group.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"iTRAQ4plex-117, mTRAQ heavy, reporter+balance reagent acylated residue","termid":"MOD:01506"},{"relation_name":"is_a","term_name":"iTRAQ4plex reporter+balance reagent O-acylated residue","termid":"MOD:01713"},{"relation_name":"is_a","term_name":"O3-acylated L-serine","termid":"MOD:02003"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"iTRAQ4plex-117 reporter+balance reagent O3-acylated serine","synonyms":[{"name":"(4-methylpiperazin-1-yl)acetyl","type":"exact"},{"name":"iTRAQ4plex","type":"related"}],"termid":"MOD:01511"}


id: SO:0001094
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A binding site that, in the polypeptide molecule, interacts selectively and non-covalently with calcium ions.","definition_xrefs":["EBIBS:GAR"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polypeptide_metal_contact","termid":"SO:0001092"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"SO:0000839"}],"interesting_parent_ids":["SO:0000839"],"is_obsolete":false,"name":"polypeptide_calcium_ion_contact_site","secondary_identifiers":["BS:00186"],"synonyms":[{"name":"Ca_contact_site","type":"exact"},{"name":"ca bind","type":"related"},{"name":"ca_bind","type":"exact"},{"name":"polypeptide calcium ion contact site","type":"exact"}],"termid":"SO:0001094"}


id: PBO:0049313
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glutathione S-transferase theta 2 (gene/pseudogene)","termid":"PBO:0049313"}


id: PBO:0088155
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Vesicle membrane protein (v-SNARE) with acyltransferase activity; involved in trafficking to and within the Golgi, endocytic trafficking to the vacuole, and vacuolar fusion; membrane localization due to prenylation at the carboxy-terminus; human homolog YKT6 can complement yeast ykt6 mutant","termid":"PBO:0088155"}


id: GO:0060036
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The assembly and arrangement of a vacuole within a cell of the notochord.","definition_xrefs":["GOC:dph","PMID:10964477","GOC:cb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vacuole organization","termid":"GO:0007033"},{"relation_name":"part_of","term_name":"notochord cell development","termid":"GO:0060035"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"notochord cell vacuolation","termid":"GO:0060036"}


id: FYPO:0008009
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomere clustering is abnormal. Telomere clustering gathers telomeres during or prior to tethering to the nuclear periphery during interphase of the mitotic cell cycle.","definition_xrefs":["PomBase:mlr","PMID:15615848"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal organelle localization","termid":"FYPO:0006329"},{"relation_name":"is_a","term_name":"abnormal telomere localization to nuclear periphery","termid":"FYPO:0007418"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0001320","FYPO:0005447","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"abnormal interphase mitotic telomere clustering during vegetative growth","synonyms":[{"name":"abnormal interphase telomere clustering","type":"broad"},{"name":"abnormal mitotic interphase telomere clustering","type":"exact"},{"name":"abnormal telomere clustering during vegetative growth","type":"exact"}],"termid":"FYPO:0008009"}


id: MONDO:0044974
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete disease of supramolecular complex (obsolete MONDO:0044974)","termid":"MONDO:0044974","xrefs":{"Monarch":{"xref_id":"0044974"}}}


id: MONDO:0011937
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any peeling skin syndrome in which the cause of the disease is a mutation in the CSTA gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"exfoliative ichthyosis","termid":"MONDO:0017339"},{"relation_name":"is_a","term_name":"peeling skin syndrome","termid":"MONDO:0019347"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"peeling skin syndrome 4","secondary_identifiers":["MEDGEN:895692","GARD:18426","DOID:0070523","UMLS:C4225407","MESH:C564309","OMIM:607936"],"synonyms":[{"name":"CSTA peeling skin syndrome","type":"exact"},{"name":"PSS4","type":"related"},{"name":"ichthyosis bullosa of Siemens-like","type":"related"},{"name":"ichthyosis, exfoliative, autosomal recessive","type":"related"},{"name":"peeling skin syndrome 4","type":"exact"},{"name":"peeling skin syndrome caused by mutation in CSTA","type":"exact"},{"name":"peeling skin syndrome type 4","type":"exact"}],"termid":"MONDO:0011937","xrefs":{"Monarch":{"xref_id":"0011937"}}}


id: GO:0106183
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the translocation of carbohydrates and their derivatives.","definition_xrefs":["GOC:hjd"],"gene_count":0,"genotype_count":0,"name":"obsolete translocase activity acting on carbohydrates and their derivatives. (obsolete GO:0106183)","termid":"GO:0106183"}


id: PBO:0041649
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CACNA2D3 antisense RNA 1","termid":"PBO:0041649"}


id: MONDO:0017091
data:
  {"annotated_genes":["SJAG_04537","SJAG_04003","SJAG_02289"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87264],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012986"},{"annotations":[87265],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012399"},{"annotations":[89073],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0030669"},{"annotations":[86880],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014679"},{"annotations":[87829],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0030482"}]},"cv_name":"mondo","definition":"Bilateral polymicrogyria is a rare cerebral malformation due to abnormal neuronal migration defined as a cerebral cortex with many excessively small convolutions. It presents with developmental delay, intellectual disability, seizures and various neurological impairments and may be isolated or comprise a clinical feature of many genetic syndromes. It may also be associated with perinatal cytomegalovirus infection.","definition_xrefs":["Orphanet:268940"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polymicrogyria","termid":"MONDO:0000087"}],"gene_count":3,"genes_by_uniquename":{"SJAG_02289":null,"SJAG_04003":null,"SJAG_04537":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320"],"is_obsolete":false,"name":"bilateral polymicrogyria","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["SCTID:765757003","GARD:17269","icd11.foundation:422828750","MEDGEN:1647593","UMLS:C4707565"],"termid":"MONDO:0017091","terms_by_termid":{"MONDO:0012399":null,"MONDO:0012986":null,"MONDO:0014679":null,"MONDO:0030482":null,"MONDO:0030669":null},"xrefs":{"Monarch":{"xref_id":"0017091"}}}


id: GO:0006923
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The proteolytic degradation of cytoskeletal proteins that contributes to apoptosis, leading to the collapse of cytoskeletal structures.","definition_xrefs":["GOC:mtg_apoptosis","ISBN:0815332181","GOC:mah","GOC:tb","GOC:dph"],"gene_count":0,"genotype_count":0,"name":"obsolete cleavage of cytoskeletal proteins involved in execution phase of apoptosis (obsolete GO:0006923)","synonyms":[{"name":"apoptotic cleavage of cytoskeletal proteins","type":"exact"},{"name":"cleavage of cytoskeletal proteins involved in apoptosis","type":"broad"},{"name":"cleavage of cytoskeletal proteins involved in execution phase of apoptosis","type":"exact"}],"termid":"GO:0006923"}


id: PBO:0085255
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Peripheral membrane protein required for autophagic vesicle formation; also required for vesicle formation during pexophagy and the cytoplasm-to-vaucole targeting (Cvt) pathway; involved in Atg9p cycling between the phagophore assembly site and mitochondria; contains an APT1 domain that binds phosphatidylinositol-3-phosphate; essential for cell cycle progression from G2/M to G1 under nitrogen starvation; forms cytoplasmic foci upon DNA replication stress","termid":"PBO:0085255"}


id: GO:0032478
data:
  {"annotated_genes":["SJAG_04568","SJAG_01865"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[93645,115604],"is_not":false,"summary":null,"term":"GO:0032478"}]},"cv_name":"cellular_component","definition":"A heterotetrameric complex located in the mitochondrial inner membrane that possesses polyprenyl diphosphate synthase activity involved in the synthesis of the isoprenoid chain of ubiquinone whose length varies between organisms. In S. pombe it is a heterotetramer of Dlp1 and Dps1.","definition_xrefs":["PMID:16262699","PMID:14519123"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polyprenyl diphosphate synthase complex","termid":"GO:0032476"},{"relation_name":"is_a","term_name":"inner mitochondrial membrane protein complex","termid":"GO:0098800"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01865":null,"SJAG_04568":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"part_of","termid":"GO:0005739"}],"interesting_parent_ids":["GO:0032991","GO:0005737","GO:0005575","GO:0005739"],"is_obsolete":false,"name":"heterotetrameric polyprenyl diphosphate synthase complex","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"heterotetrameric decaprenyl diphosphate synthase complex","type":"narrow"}],"termid":"GO:0032478","terms_by_termid":{"GO:0032478":null}}


id: MONDO:0032573
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"bone marrow failure syndrome","termid":"MONDO:0000159"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0005046"],"is_obsolete":false,"name":"bone marrow failure syndrome 5","secondary_identifiers":["MEDGEN:1648380","UMLS:C4748488","OMIM:618165"],"synonyms":[{"name":"BMFS5","type":"related"},{"name":"BONE MARROW FAILURE SYNDROME 5","type":"related"}],"termid":"MONDO:0032573","xrefs":{"Monarch":{"xref_id":"0032573"}}}


id: PBO:0085108
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Nuclear thiol peroxidase; functions as an alkyl-hydroperoxide reductase during post-diauxic growth","termid":"PBO:0085108"}


id: GO:0033138
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of protein phosphorylation","termid":"GO:0001934"},{"relation_name":"is_a","term_name":"regulation of peptidyl-serine phosphorylation","termid":"GO:0033135"},{"relation_name":"positively_regulates","term_name":"peptidyl-serine phosphorylation","termid":"GO:0018105"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of peptidyl-serine phosphorylation","termid":"GO:0033138"}


id: PBO:0091846
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Schizosaccharomyces specific microprotein Smp2","termid":"PBO:0091846"}


id: GO:0099120
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of a non-reproductive fruiting body over time, from its formation to the mature structure. A non-reproductive fruiting body is a colonial multicellular structure consisting of co-operating unicellular organisms, some of which are spores. An example of such a process is found in Dictyostelium discoideum and Myxococcus xanthus colonies.","definition_xrefs":["GOC:pf","PMID:12448714"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure development","termid":"GO:0048856"},{"relation_name":"is_a","term_name":"biological process involved in intraspecies interaction between organisms","termid":"GO:0051703"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"socially cooperative development","secondary_identifiers":["GO:0090702"],"synonyms":[{"name":"colonial development","type":"exact"},{"name":"non-reproductive fruiting body development","type":"related"},{"name":"socially co-operative development","type":"exact"}],"termid":"GO:0099120"}


id: PBO:0076966
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TGIF2-RAB5IF readthrough","termid":"PBO:0076966"}


id: PBO:0052255
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"KDEL endoplasmic reticulum protein retention receptor 2","termid":"PBO:0052255"}


id: MONDO:0011107
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A very rare syndrome characterized by sparse and short hair from birth followed by progressive macular degeneration leading to blindness.","definition_xrefs":["Orphanet:1573"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hypotrichosis","termid":"MONDO:0003037"},{"relation_name":"is_a","term_name":"ectodermal dysplasia syndrome","termid":"MONDO:0019287"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"congenital hypotrichosis with juvenile macular dystrophy","secondary_identifiers":["DOID:0110711","OMIM:601553","MESH:C537698","GARD:3066","MEDGEN:316921","UMLS:C1832162"],"synonyms":[{"name":"HJMD","type":"exact"},{"name":"Hjmd","type":"exact"},{"name":"hypotrichosis with cone-rod dystrophy","type":"exact"},{"name":"hypotrichosis with juvenile macular degeneration","type":"related"},{"name":"hypotrichosis with juvenile macular dystrophy","type":"exact"},{"name":"hypotrichosis, congenital, with juvenile macular dystrophy","type":"related"},{"name":"juvenile macular degeneration and hypotrichosis","type":"related"},{"name":"juvenile macular dystrophy and congenital hypotrichosis","type":"related"}],"termid":"MONDO:0011107","xrefs":{"Monarch":{"xref_id":"0011107"}}}


id: GO:1903350
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus.","definition_xrefs":["GO_REF:0000071","GOC:TermGenie","PMID:11118945","GOC:mr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to catecholamine","termid":"GO:0071869"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to dopamine","termid":"GO:1903350"}


id: MONDO:0009871
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Pili torti-developmental delay-neurological abnormalities syndrome is characterized by growth and developmental delay, mild to moderate neurologic abnormalities, and pili torti. It has been described in a brother and his sister born to consanguineous Puerto Rican parents.","definition_xrefs":["Orphanet:2891"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pili torti-developmental delay-neurological abnormalities syndrome","secondary_identifiers":["MEDGEN:342358","UMLS:C1849811","OMIM:261990","GARD:4362","MESH:C537398"],"synonyms":[{"name":"abnormal hair, joint laxity, and developmental delay","type":"exact"},{"name":"pili torti and developmental delay","type":"related"},{"name":"pili torti developmental delay neurological abnormalities","type":"related"}],"termid":"MONDO:0009871","xrefs":{"Monarch":{"xref_id":"0009871"}}}


id: GO:0048853
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of the forebrain are generated and organized. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).","definition_xrefs":["GOC:cvs","GOC:dph","GOC:jid","GOC:dgh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure morphogenesis","termid":"GO:0009653"},{"relation_name":"part_of","term_name":"forebrain development","termid":"GO:0030900"},{"relation_name":"part_of","term_name":"brain morphogenesis","termid":"GO:0048854"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"forebrain morphogenesis","synonyms":[{"name":"prosencephalon morphogenesis","type":"exact"}],"termid":"GO:0048853"}


id: PBO:0066576
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RHEB like 1","termid":"PBO:0066576"}


id: MONDO:0018362
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"nervous system disorder","termid":"MONDO:0005071"},{"relation_name":"is_a","term_name":"idiopathic disease","termid":"MONDO:0700007"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"persistent idiopathic facial pain","secondary_identifiers":["icd11.foundation:1799118131","MEDGEN:1673850","UMLS:C5191641","GARD:21649","Orphanet:398147","ICD10CM:G50.1"],"synonyms":[{"name":"AFP","type":"exact"},{"name":"PIFP","type":"exact"},{"name":"atypical facial pain","type":"exact"}],"termid":"MONDO:0018362","xrefs":{"Monarch":{"xref_id":"0018362"}}}


id: GO:0060546
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.","definition_xrefs":["GOC:mtg_apoptosis","GOC:dph","GOC:BHF","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of necroptotic process","termid":"GO:0060544"},{"relation_name":"is_a","term_name":"negative regulation of programmed necrotic cell death","termid":"GO:0062099"},{"relation_name":"negatively_regulates","term_name":"necroptotic process","termid":"GO:0070266"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of necroptotic process","synonyms":[{"name":"negative regulation of necroptosis","type":"narrow"}],"termid":"GO:0060546"}


id: PBO:0086975
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Regulatory subunit of the Atg1p signaling complex; stimulates Atg1p kinase activity; required for vesicle formation during autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; contains a HORMA domain required for autophagy and for recruitment of the phosphatidylinositol 3-kinase complex subunit Atg14p to the pre-autophagosomal structure","termid":"PBO:0086975"}


id: PBO:0029623
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_protein_kinase_activity_during_cellular_response_to_hydroxyurea","termid":"PBO:0029623"}


id: GO:0035896
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process in which an organism increases the frequency, rate or extent of blood mast cell degranulation in another organism.","definition_xrefs":["GOC:bf","GOC:fj"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of mast cell degranulation in another organism (obsolete GO:0035896)","synonyms":[{"name":"positive regulation of mast cell degranulation in other organism","type":"exact"},{"name":"up-regulation of mast cell degranulation in other organism","type":"related"},{"name":"upregulation of mast cell degranulation in other organism","type":"exact"}],"termid":"GO:0035896"}


id: PBO:0090380
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial [2Fe-2S] cluster assembly frataxin Fxn1","termid":"PBO:0090380"}


id: PBO:0056758
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"methyltransferase 13, eEF1A lysine and N-terminal methyltransferase","termid":"PBO:0056758"}


id: GO:0044589
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to pectin.","definition_xrefs":["GOC:tt","GOC:mengo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"galacturonan binding","termid":"GO:0048028"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0003674","GO:0005488"],"is_obsolete":false,"name":"pectin binding","termid":"GO:0044589"}


id: PBO:0086093
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein phosphotyrosine phosphatase of unknown cellular role; activated by adenine","termid":"PBO:0086093"}


id: PBO:0077884
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"translocated promoter region, nuclear basket protein","termid":"PBO:0077884"}


id: PBO:0050551
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"human papillomavirus (type 6a) integration site 1","termid":"PBO:0050551"}


id: GO:0070612
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: S-adenosyl-L-methionine + (histone H2A)-arginine (position 3) = S-adenosyl-L-homocysteine + (histone H2A)-N-methyl-arginine (position 3). This reaction is the addition of a methyl group to the arginine residue at position 3 of histone H2A.","definition_xrefs":["PMID:23451136","PMID:17898714","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-arginine N-methyltransferase activity","termid":"GO:0016274"},{"relation_name":"is_a","term_name":"histone H2A methyltransferase activity","termid":"GO:0140940"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008276"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016741"}],"interesting_parent_ids":["GO:0016741","GO:0140096","GO:0003674","GO:0003824","GO:0008276","GO:0016740"],"is_obsolete":false,"name":"histone H2AR3 methyltransferase activity","synonyms":[{"name":"histone H2AR3 arginine methyltransferase activity","type":"exact"},{"name":"histone methylase activity (H2A-R3 specific)","type":"exact"},{"name":"histone methyltransferase activity (H2A-R3 specific)","type":"exact"},{"name":"histone-H2AR3 methyltransferase activity","type":"exact"},{"name":"histone-arginine N-methyltransferase activity (H2A-R3 specific)","type":"exact"}],"termid":"GO:0070612"}


id: SO:0000359
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"An attribute describing sequence that is flanked by Lox-P sites.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"flanked","termid":"SO:0000357"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"floxed","secondary_identifiers":["http://en.wikipedia.org/wiki/Floxed"],"termid":"SO:0000359"}


id: PBO:0070268
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, variant U1 small nuclear 2A","termid":"PBO:0070268"}


id: MONDO:0015614
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Dermatitis herpetiformis (DH) is a chronic autoimmune subepidermal bullous disease characterized by grouped pruritic lesions such as papules, urticarial plaques, erythema, and herpetiform vesiculae, with a predominantly symmetrical distribution on extensor surfaces of the elbows (90%), knees (30%), shoulders, buttocks, sacral region, and face of children and adults. Erosions, excoriations and hyperpigmentation usually follow. DH may also appear as a consequence of gluten intolerance.","definition_xrefs":["Orphanet:1656"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autoimmune bullous skin disease","termid":"MONDO:0019337"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005093","MONDO:0005046"],"is_obsolete":false,"name":"dermatitis herpetiformis","secondary_identifiers":["Wikipedia:Dermatitis_herpetiformis","ICD10CM:L13.0","icd11.foundation:286313127","NCIT:C26742","GARD:10075","EFO:1000684","MedDRA:10012468","UMLS:C0011608","MESH:D003874","DOID:8505","MEDGEN:8327","SCTID:111196000","ICD9:694.0"],"synonyms":[{"name":"Duhring's disease","type":"exact"},{"name":"Durhing-Brocq disease","type":"exact"},{"name":"dermatitis herpetiformis","type":"exact"},{"name":"dermatosis herpetiformis","type":"exact"}],"termid":"MONDO:0015614","xrefs":{"Monarch":{"xref_id":"0015614"}}}


id: FYPO:0007839
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of peptide alpha-N-acetyltransferase activity is abnormal.","definition_xrefs":["PomBase:mah","PMID:34019809"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal catalytic activity","termid":"FYPO:0000661"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000654","FYPO:0000652","FYPO:0000707","FYPO:0001985","FYPO:0000661"],"is_obsolete":false,"name":"abnormal peptide alpha-N-acetyltransferase activity","synonyms":[{"name":"abnormal NAT activity","type":"related"},{"name":"abnormal protein N-terminal acetyltransferase activity","type":"exact"}],"termid":"FYPO:0007839"}


id: PBO:0000691
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coproporphyrinogen III oxidase (predicted)","termid":"PBO:0000691"}


id: MONDO:0003821
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A germ cell tumor that arises from the ovary and is composed of tissues that originate from two or three of the following germ layers, endoderm, ectoderm, or mesoderm.","definition_xrefs":["NCIT:C39992"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ovarian teratoma","termid":"MONDO:0005602"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ovarian biphasic or triphasic teratoma","secondary_identifiers":["MEDGEN:274086","UMLS:C1518691","DOID:6232"],"synonyms":[{"name":"ovarian biphasic or triphasic teratoma","type":"exact"}],"termid":"MONDO:0003821","xrefs":{"Monarch":{"xref_id":"0003821"}}}


id: FYPO:0001644
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of lithium ions measured in a cell is lower than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased level of substance in cell during vegetative growth","termid":"FYPO:0001329"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"decreased cellular lithium level","synonyms":[{"name":"decreased cellular lithium ion level","type":"exact"},{"name":"decreased cellular lithium level during mitotic cell cycle","type":"related"},{"name":"decreased cellular lithium level during vegetative growth","type":"exact"},{"name":"decreased lithium accumulation","type":"related"},{"name":"reduced cellular lithium level","type":"exact"}],"termid":"FYPO:0001644"}


id: GO:0097517
data:
  {"annotated_genes":["SJAG_01739"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[67279],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0001725"}]},"cv_name":"cellular_component","definition":"An actin filament bundle in which the filaments are loosely packed (approximately 30-60 nm apart) and arranged with opposing polarities; the loose packing allows myosin (usually myosin-II) to enter the bundle.","definition_xrefs":["GOC:cjm","GOC:mah","ISBN:0815316194"],"direct_ancestors":[{"relation_name":"is_a","term_name":"actin filament bundle","termid":"GO:0032432"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01739":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0015629"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0015629"],"is_obsolete":false,"name":"contractile actin filament bundle","references_by_uniquename":{"GO_REF:0000044":null},"termid":"GO:0097517","terms_by_termid":{"GO:0001725":null}}


id: GO:0052789
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the hydrolysis of (1->3)-beta-D-mannosidic linkages in mannans, releasing mannose.","definition_xrefs":["GOC:mengo_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete mannan 1,3-beta-mannosidase activity (obsolete GO:0052789)","termid":"GO:0052789"}


id: MONDO:1011879
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"nervous system disorder, non-human animal","termid":"MONDO:1011336"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"necrotizing meningoencephalitis, non-human animal","secondary_identifiers":["OMIA:001470"],"termid":"MONDO:1011879","xrefs":{"Monarch":{"xref_id":"1011879"}}}


id: PBO:0042275
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chaperonin containing TCP1 subunit 8 like 1, pseudogene","termid":"PBO:0042275"}


id: PBO:0072455
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S29 pseudogene 19","termid":"PBO:0072455"}


id: MONDO:0002523
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"The mucinoses are a diverse group of disorders which have in common the deposition of basophilic, finely granular and stringy material (mucin) in the connective tissues of the dermis (dermal mucinoses), in the pilosebaceous follicles (follicular mucinoses), or in the epidermis and tumors derived therefrom (epithelial mucinoses).","definition_xrefs":["ISBN-13:978-0-7020-3485-5"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"connective tissue disorder","termid":"MONDO:0003900"},{"relation_name":"is_a","term_name":"skin disorder","termid":"MONDO:0005093"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"cutaneous mucinosis","secondary_identifiers":["DOID:3141","SCTID:402721001","ICD9:701.8","MESH:D017520","MEDGEN:56520","icd11.foundation:2018255084","UMLS:C0162855"],"synonyms":[{"name":"mucinoses","type":"related"},{"name":"mucinosis","type":"exact"},{"name":"mucinosis affecting the skin","type":"exact"}],"termid":"MONDO:0002523","xrefs":{"Monarch":{"xref_id":"0002523"}}}


id: PBO:0003244
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Tre1 family protein, involved in vacuolar protein degradation (predicted)","termid":"PBO:0003244"}


id: GO:0019139
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: N6-dimethylallyladenine + acceptor + H2O = adenine + 3-methylbut-2-enal + reduced electron acceptor.","definition_xrefs":["EC:1.5.99.12"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-NH group of donors","termid":"GO:0016645"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"cytokinin dehydrogenase activity","secondary_identifiers":["MetaCyc:1.5.99.12-RXN","RHEA:13625","GO:0046420"],"synonyms":[{"name":"6-N-dimethylallyladenine:acceptor oxidoreductase activity","type":"related"},{"name":"N6-dimethylallyladenine:(acceptor) oxidoreductase activity","type":"related"},{"name":"N6-dimethylallyladenine:acceptor oxidoreductase activity","type":"related"},{"name":"cytokinin oxidase activity","type":"related"}],"termid":"GO:0019139"}


id: GO:0102391
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: ATP + decanoate + CoA = AMP + diphosphate + decanoyl-CoA.","definition_xrefs":["GOC:pz","RHEA:33627"],"direct_ancestors":[{"relation_name":"is_a","term_name":"medium-chain fatty acid-CoA ligase activity","termid":"GO:0031956"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016874"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016874","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"decanoate-CoA ligase activity","secondary_identifiers":["MetaCyc:RXN-13614"],"termid":"GO:0102391"}


id: GO:0106107
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of (R)-mevalonic acid biosynthetic process.","definition_xrefs":["GOC:BHF_miRNA","PMID:24296663","GOC:rph","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of biosynthetic process","termid":"GO:0009889"},{"relation_name":"is_a","term_name":"regulation of small molecule metabolic process","termid":"GO:0062012"},{"relation_name":"regulates","term_name":"(R)-mevalonic acid biosynthetic process","termid":"GO:1901737"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0008150"],"is_obsolete":false,"name":"regulation of (R)-mevalonic acid biosynthetic process","termid":"GO:0106107"}


id: PBO:0111805
data:
  {"annotation_feature_type":"gene","cv_name":"pombase_family_or_domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glycogen synthase kinase 3 (GSK-3) subfamily","termid":"PBO:0111805"}


id: GO:0071995
data:
  {"annotated_genes":["SJAG_05213","SJAG_03497","SJAG_01344"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[97889,98864,120073],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0036246"}]},"cv_name":"biological_process","definition":"The directed movement of phytochelatins into the vacuole. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.","definition_xrefs":["GOC:mah","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vacuolar transmembrane transport","termid":"GO:0034486"},{"relation_name":"is_a","term_name":"phytochelatin transmembrane transport","termid":"GO:0071994"}],"gene_count":3,"genes_by_uniquename":{"SJAG_01344":null,"SJAG_03497":null,"SJAG_05213":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0006810","GO:0051179","GO:0055085"],"is_obsolete":false,"name":"phytochelatin import into vacuole","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"cadystin import into vacuole","type":"related"},{"name":"phytochelatin transport into vacuole","type":"exact"}],"termid":"GO:0071995","terms_by_termid":{"GO:0036246":null}}


id: PBO:0043863
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"crumbs cell polarity complex component 1","termid":"PBO:0043863"}


id: PBO:0077734
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tensin 2","termid":"PBO:0077734"}


id: PBO:0058157
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4452","termid":"PBO:0058157"}


id: PR:Q8TF80
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- wtf5 gene.","definition_xrefs":["UniProtKB:Q8TF80","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein wtf5 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC794.02","synonyms":[{"name":"Spom972h-wtf5","type":"exact"}],"termid":"PR:Q8TF80"}


id: GO:0052655
data:
  {"annotated_genes":["SJAG_04149"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[112287],"is_not":false,"summary":null,"term":"GO:0052655"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: 2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoic acid + L-glutamatic acid.","definition_xrefs":["RHEA:24813"],"direct_ancestors":[{"relation_name":"is_a","term_name":"branched-chain-amino-acid transaminase activity","termid":"GO:0004084"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04149":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016769"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0016769","GO:0003674","GO:0003824","GO:0016740"],"is_obsolete":false,"name":"L-valine-2-oxoglutarate transaminase activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["MetaCyc:BRANCHED-CHAINAMINOTRANSFERVAL-RXN","KEGG_REACTION:R01214"],"synonyms":[{"name":"L-valine aminotransferase activity","type":"exact"}],"termid":"GO:0052655","terms_by_termid":{"GO:0052655":null}}


id: FYPO:0003726
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any myo-inositol pentakisphosphate measured in a cell is higher than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased level of substance in cell during vegetative growth","termid":"FYPO:0001330"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320","FYPO:0001985"],"is_obsolete":false,"name":"increased cellular inositol pentakisphosphate level","synonyms":[{"name":"increased cellular inositol pentakisphosphate level during mitotic cell cycle","type":"related"},{"name":"increased cellular inositol pentakisphosphate level during vegetative growth","type":"exact"},{"name":"increased cellular myo-inositol pentakisphosphate level","type":"exact"},{"name":"increased inositol pentakisphosphate accumulation","type":"related"}],"termid":"FYPO:0003726"}


id: PBO:0082807
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of UDP-GlcNAc transferase; required for second step of dolichyl-linked oligosaccharide synthesis; anchors catalytic subunit Alg13p to ER membrane; similar to bacterial and human glycosyltransferases; both human homologs ALG13 and ALG14 are required to complement yeast alg14 mutant; mutations of human ALG14 cause congenital myasthenic syndrome","termid":"PBO:0082807"}


id: MONDO:0011711
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"specific language impairment","termid":"MONDO:0000724"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"specific language impairment 2","secondary_identifiers":["OMIM:606712","UMLS:C1847605","MEDGEN:338273"],"synonyms":[{"name":"SLI2","type":"exact"},{"name":"specific language impairment 2","type":"exact"},{"name":"specific language impairment QTL, 2","type":"exact"},{"name":"specific language impairment quantitative trait locus on chromosome 19","type":"related"}],"termid":"MONDO:0011711","xrefs":{"Monarch":{"xref_id":"0011711"}}}


id: MONDO:0018412
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete rare female infertility due to adrenal disorder of genetic origin (obsolete MONDO:0018412)","secondary_identifiers":["Orphanet:400018"],"termid":"MONDO:0018412","xrefs":{"Monarch":{"xref_id":"0018412"}}}


id: PR:Q92348
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mug183 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q92348"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiotically up-regulated gene 183 protein (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC6G9.03c","synonyms":[{"name":"Spom972h-mug183","type":"exact"}],"termid":"PR:Q92348"}


id: MONDO:0008802
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"antithrombin, familial hemorrhagic diathesis due to","secondary_identifiers":["OMIM:207300","MESH:C565947","MEDGEN:347227","UMLS:C1859761"],"synonyms":[{"name":"antithrombin, familial hemorrhagic diathesis due to","type":"exact"}],"termid":"MONDO:0008802","xrefs":{"Monarch":{"xref_id":"0008802"}}}


id: PBO:0082247
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p); capping protein (CP) binds to the barbed ends of actin filaments preventing further polymerization; localized predominantly to cortical actin patches; protein increases in abundance and relocalizes from bud neck to plasma membrane upon DNA replication stress","termid":"PBO:0082247"}


id: PBO:0080496
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"von Willebrand factor D and EGF domains","termid":"PBO:0080496"}


id: FYPO:0000733
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A spindle phenotype in which the mitotic spindle is longer than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"long spindle","termid":"FYPO:0000730"},{"relation_name":"is_a","term_name":"abnormal bipolar mitotic spindle","termid":"FYPO:0001574"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0000054"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000120"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0002399"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001985","FYPO:0000120","FYPO:0001320","FYPO:0000054","FYPO:0002399","FYPO:0000002"],"is_obsolete":false,"name":"long mitotic spindle","synonyms":[{"name":"elongated mitotic spindle","type":"exact"},{"name":"increased mitotic spindle length","type":"exact"},{"name":"long bipolar mitotic spindle","type":"exact"},{"name":"long mitotic spindle during vegetative growth","type":"exact"},{"name":"long mitotic spindles","type":"exact"},{"name":"long spindle during mitosis","type":"exact"},{"name":"long spindle during mitotic cell cycle","type":"related"}],"termid":"FYPO:0000733"}


id: GO:0004925
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with prolactin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.","definition_xrefs":["GOC:signaling","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytokine receptor activity","termid":"GO:0004896"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0038023"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0038023","GO:0003674"],"is_obsolete":false,"name":"prolactin receptor activity","termid":"GO:0004925"}


id: MONDO:0056821
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete bronchiolitis obliterans organizing pneumonia (obsolete MONDO:0056821)","termid":"MONDO:0056821","xrefs":{"Monarch":{"xref_id":"0056821"}}}


id: PBO:0059221
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"maestro heat like repeat family member 3, pseudogene","termid":"PBO:0059221"}


id: PBO:0062967
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"poly(A) binding protein cytoplasmic 1 pseudogene 10","termid":"PBO:0062967"}


id: MONDO:0012871
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any Jervell and Lange-Nielsen syndrome in which the cause of the disease is a mutation in the KCNE1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Jervell and Lange-Nielsen syndrome","termid":"MONDO:0002441"},{"relation_name":"is_a","term_name":"long QT syndrome 5","termid":"MONDO:0013372"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"Jervell and Lange-Nielsen syndrome 2","secondary_identifiers":["GARD:10364","MEDGEN:394108","OMIM:612347","MESH:C567343","UMLS:C2676723"],"synonyms":[{"name":"JLNS2","type":"related"},{"name":"Jervell and Lange-Nielsen syndrome 2","type":"exact"},{"name":"Jervell and Lange-Nielsen syndrome caused by mutation in KCNE1","type":"exact"},{"name":"Jervell and Lange-Nielsen syndrome type 2","type":"exact"},{"name":"KCNE1 Jervell and Lange-Nielsen syndrome","type":"exact"}],"termid":"MONDO:0012871","xrefs":{"Monarch":{"xref_id":"0012871"}}}


id: PBO:0080645
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WD repeat domain 93","termid":"PBO:0080645"}


id: PBO:0002919
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2 OG-Fe(II) oxygenase superfamily protein Ofd2","termid":"PBO:0002919"}


id: GO:0009134
data:
  {"annotated_genes":["SJAG_02009","SJAG_03676","SJAG_03828","SJAG_06621","SJAG_02945","SJAG_02369","SJAG_04495","SJAG_06622","SJAG_03660","SJAG_03373","SJAG_00605","SJAG_00027","SJAG_01595","SJAG_00461","SJAG_04334","SJAG_04048","SJAG_02796","SJAG_02107","SJAG_00685","SJAG_00839","SJAG_05314","SJAG_03903","SJAG_04192","SJAG_01310","SJAG_02785","SJAG_02135","SJAG_03977"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[72254],"is_not":false,"summary":null,"term":"GO:0009134"},{"annotations":[100077,111236,111237,99806,111238,111239,111235,118208,105459,105202,74174,111240,111241,107280,107282,107650,107651,79584,107281,96338],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061621"},{"annotations":[90422],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061613"},{"annotations":[77883,74826],"is_not":false,"rel_names":["negatively_regulates","regulates"],"summary":null,"term":"GO:0045820"},{"annotations":[71755],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0006110"},{"annotations":[115169],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009191"},{"annotations":[78196],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006256"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.","definition_xrefs":["GOC:go_curators","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleoside diphosphate metabolic process","termid":"GO:0009132"},{"relation_name":"is_a","term_name":"nucleoside phosphate catabolic process","termid":"GO:1901292"}],"gene_count":27,"genes_by_uniquename":{"SJAG_00027":null,"SJAG_00461":null,"SJAG_00605":null,"SJAG_00685":null,"SJAG_00839":null,"SJAG_01310":null,"SJAG_01595":null,"SJAG_02009":null,"SJAG_02107":null,"SJAG_02135":null,"SJAG_02369":null,"SJAG_02785":null,"SJAG_02796":null,"SJAG_02945":null,"SJAG_03373":null,"SJAG_03660":null,"SJAG_03676":null,"SJAG_03828":null,"SJAG_03903":null,"SJAG_03977":null,"SJAG_04048":null,"SJAG_04192":null,"SJAG_04334":null,"SJAG_04495":null,"SJAG_05314":null,"SJAG_06621":null,"SJAG_06622":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0055086","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"nucleoside diphosphate catabolic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"nucleoside diphosphate breakdown","type":"exact"},{"name":"nucleoside diphosphate catabolism","type":"exact"},{"name":"nucleoside diphosphate degradation","type":"exact"}],"termid":"GO:0009134","terms_by_termid":{"GO:0006110":null,"GO:0006256":null,"GO:0009134":null,"GO:0009191":null,"GO:0045820":null,"GO:0061613":null,"GO:0061621":null}}


id: GO:0102341
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: (R)-3-hydroxylignoceroyl-CoA + NADP = 3-oxotetracosanoyl-CoA + NADPH + H+.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete 3-oxo-lignoceroyl-CoA reductase activity (obsolete GO:0102341)","termid":"GO:0102341"}


id: PATO:0002123
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"Being smallest in amount, extent or degree.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"present","termid":"PATO:0000467"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"minimal","termid":"PATO:0002123"}


id: PBO:0061785
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"oncomodulin","termid":"PBO:0061785"}


id: GO:0033025
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of mast cell apoptotic process.","definition_xrefs":["GOC:add","GOC:mtg_apoptosis"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of immune system process","termid":"GO:0002682"},{"relation_name":"is_a","term_name":"regulation of myeloid cell apoptotic process","termid":"GO:0033032"},{"relation_name":"is_a","term_name":"regulation of leukocyte apoptotic process","termid":"GO:2000106"},{"relation_name":"regulates","term_name":"mast cell apoptotic process","termid":"GO:0033024"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of mast cell apoptotic process","synonyms":[{"name":"regulation of mast cell apoptosis","type":"narrow"}],"termid":"GO:0033025"}


id: GO:0071115
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that consists of an alpha5-beta1 integrin complex bound to endostatin, the NC1 domain of the alpha1 chain of type XVIII collagen.","definition_xrefs":["PMID:12682293"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plasma membrane protein complex","termid":"GO:0098797"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005886"}],"interesting_parent_ids":["GO:0032991","GO:0005886","GO:0005575"],"is_obsolete":false,"name":"alpha5-beta1 integrin-endostatin complex","synonyms":[{"name":"ITGA5-ITGB1-CAL4A3 complex","type":"narrow"}],"termid":"GO:0071115"}


id: GO:0090271
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.","definition_xrefs":["GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cytokine production","termid":"GO:0001819"},{"relation_name":"is_a","term_name":"regulation of fibroblast growth factor production","termid":"GO:0090270"},{"relation_name":"positively_regulates","term_name":"fibroblast growth factor production","termid":"GO:0090269"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"positively_regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"positive regulation of fibroblast growth factor production","termid":"GO:0090271"}


id: PBO:0069289
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 545, pseudogene","termid":"PBO:0069289"}


id: GO:0071280
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to copper ion","termid":"GO:0046688"},{"relation_name":"is_a","term_name":"cellular response to metal ion","termid":"GO:0071248"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to copper ion","synonyms":[{"name":"cellular response to copper","type":"exact"}],"termid":"GO:0071280"}


id: PBO:0036095
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-mislocalized_eMTOC","termid":"PBO:0036095"}


id: PBO:0045026
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DIRC3 antisense RNA 1","termid":"PBO:0045026"}


id: MONDO:0002164
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"chorioretinitis","termid":"MONDO:0004674"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"focal chorioretinitis","secondary_identifiers":["DOID:1979","ICD10CM:H30.0","ICD9:363.0","MEDGEN:509691","SCTID:15847003","UMLS:C0154870","ICD9:363.00"],"termid":"MONDO:0002164","xrefs":{"Monarch":{"xref_id":"0002164"}}}


id: PBO:0039143
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"adenylate kinase 2","termid":"PBO:0039143"}


id: SO:0000180
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A transposable element that is incorporated into a chromosome by a mechanism that requires reverse transcriptase.","direct_ancestors":[{"relation_name":"is_a","term_name":"transposable_element","termid":"SO:0000101"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"retrotransposon","secondary_identifiers":["http://en.wikipedia.org/wiki/Retrotransposon"],"synonyms":[{"name":"class I","type":"related"},{"name":"class I transposon","type":"exact"},{"name":"retrotransposon element","type":"exact"}],"termid":"SO:0000180"}


id: MONDO:0007670
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hypotrichosis - lymphedema - telangiectasia is an extremely rare syndromic lymphedema disorder characterized by early-onset hypotrichosis, childhood-onset lymphedema, and variable telangiectasia, particularly of the palms.","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"primary lymphedema","termid":"MONDO:0019175"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"hypotrichosis-lymphedema-telangiectasia syndrome (grouping)","secondary_identifiers":["GARD:12827","Orphanet:69735"],"synonyms":[{"name":"hypotrichosis lymphedema telangiectasia syndrome","type":"related"}],"termid":"MONDO:0007670","xrefs":{"Monarch":{"xref_id":"0007670"}}}


id: PR:O14355
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPBC30D10.09c gene.","definition_xrefs":["PRO:DNx","UniProtKB:O14355"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized membrane protein C30D10.09c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC30D10.09c","synonyms":[{"name":"Spom972h-SPBC30D10.09c","type":"exact"}],"termid":"PR:O14355"}


id: FYPO:0005079
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at the central core of the centromeric regions is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PMID:21151114","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein localization to chromatin during vegetative growth","termid":"FYPO:0001509"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001312","FYPO:0000257","FYPO:0000138","FYPO:0001320"],"is_obsolete":false,"name":"normal protein localization to chromatin at centromere central core","synonyms":[{"name":"normal protein localisation to chromatin at centromere central core","type":"exact"},{"name":"normal protein localization to chromatin at centromere central core during mitotic cell cycle","type":"related"},{"name":"normal protein localization to chromatin at centromere central core during vegetative growth","type":"exact"},{"name":"normal protein localization to chromatin at centromeric central core","type":"exact"}],"termid":"FYPO:0005079"}


id: PBO:0091823
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"not functionally complemented by A. thaliana cdc2aAt","termid":"PBO:0091823"}


id: GO:1902407
data:
  {"annotated_genes":["SJAG_02700","SJAG_04887","SJAG_02431","SJAG_04982","SJAG_00845","SJAG_01894","SJAG_02831","SJAG_03045","SJAG_03025","SJAG_01787","SJAG_02592","SJAG_01143","SJAG_00228","SJAG_00268","SJAG_04077","SJAG_04597","SJAG_02838","SJAG_01943","SJAG_01732","SJAG_02392","SJAG_01805","SJAG_04703","SJAG_00279","SJAG_03596","SJAG_04498","SJAG_03703","SJAG_00700","SJAG_04930","SJAG_00082","SJAG_03048"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[90074,120993,68536,99462,99733,97105,120342,58838,104385,77310,94354,113720,59994,74286,78059,76686,112650,114161,70614,100713],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903475"},{"annotations":[79162],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:1903479"},{"annotations":[97668,112614,104187,105514,92579,96181],"is_not":false,"rel_names":["regulates","negatively_regulates"],"summary":null,"term":"GO:1903500"},{"annotations":[91813,96223],"is_not":false,"rel_names":["positively_regulates","regulates"],"summary":null,"term":"GO:1903501"},{"annotations":[95622,121075],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:1903499"}]},"cv_name":"biological_process","definition":"Any assembly of mitotic cytokinetic actomyosin apparatus.","definition_xrefs":["GOC:TermGenie","GOC:mtg_cell_cycle"],"direct_ancestors":[{"relation_name":"is_a","term_name":"assembly of actomyosin apparatus involved in cytokinesis","termid":"GO:0000912"},{"relation_name":"is_a","term_name":"mitotic cytokinetic process","termid":"GO:1902410"}],"gene_count":30,"genes_by_uniquename":{"SJAG_00082":null,"SJAG_00228":null,"SJAG_00268":null,"SJAG_00279":null,"SJAG_00700":null,"SJAG_00845":null,"SJAG_01143":null,"SJAG_01732":null,"SJAG_01787":null,"SJAG_01805":null,"SJAG_01894":null,"SJAG_01943":null,"SJAG_02392":null,"SJAG_02431":null,"SJAG_02592":null,"SJAG_02700":null,"SJAG_02831":null,"SJAG_02838":null,"SJAG_03025":null,"SJAG_03045":null,"SJAG_03048":null,"SJAG_03596":null,"SJAG_03703":null,"SJAG_04077":null,"SJAG_04498":null,"SJAG_04597":null,"SJAG_04703":null,"SJAG_04887":null,"SJAG_04930":null,"SJAG_04982":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0000281"},{"rel_name":"part_of","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0044085","GO:0008150","GO:0000281","GO:0007049"],"is_obsolete":false,"name":"assembly of actomyosin apparatus involved in mitotic cytokinesis","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null,"GO_REF:0000117":null,"PMID:27059155":null,"PMID:32915139":null},"synonyms":[{"name":"actomyosin apparatus assembly involved in cytokinesis involved in mitotic cell cycle","type":"exact"},{"name":"cytokinesis, formation of actomyosin apparatus involved in mitotic cell cycle","type":"exact"},{"name":"formation of actomyosin apparatus involved in cytokinesis involved in mitotic cell cycle","type":"related"}],"termid":"GO:1902407","terms_by_termid":{"GO:0120306":null,"GO:1903475":null,"GO:1903479":null,"GO:1903499":null,"GO:1903500":null,"GO:1903501":null}}


id: FYPO:0002071
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell has a nucleus in an abnormal location. The normal location of a single nucleus is at the midpoint of the long axis of the cell (during mitotic telophase, daughter nuclei normally move away from the cell division site).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular physical quality phenotype during vegetative growth","termid":"FYPO:0001321"},{"relation_name":"is_a","term_name":"mislocalized nucleus","termid":"FYPO:0002069"},{"relation_name":"output_of","term_name":"abnormal nucleus positioning during vegetative growth","termid":"FYPO:0001338"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0001320","FYPO:0000138","FYPO:0005447"],"is_obsolete":false,"name":"mislocalized nucleus during vegetative growth","synonyms":[{"name":"abnormal nucleus location during vegetative growth","type":"exact"},{"name":"abnormal nucleus position during vegetative growth","type":"exact"},{"name":"displaced nucleus during vegetative growth","type":"exact"},{"name":"mislocalised nucleus during vegetative growth","type":"exact"},{"name":"mislocalized nucleus during mitotic cell cycle","type":"related"},{"name":"misplaced nuclei during vegetative growth","type":"exact"},{"name":"misplaced nucleus during vegetative growth","type":"exact"},{"name":"nuclear displacement during vegetative growth","type":"exact"}],"termid":"FYPO:0002071"}


id: PBO:0066475
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"riboflavin kinase pseudogene 2","termid":"PBO:0066475"}


id: PBO:0034552
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_cellular_inositol_phosphorylceramide_level","termid":"PBO:0034552"}


id: GO:1900070
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of cellular hyperosmotic salinity response.","definition_xrefs":["GOC:TermGenie","PMID:16278455","GOC:dgf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cellular process","termid":"GO:0048523"},{"relation_name":"is_a","term_name":"regulation of cellular hyperosmotic salinity response","termid":"GO:1900069"},{"relation_name":"is_a","term_name":"negative regulation of response to salt stress","termid":"GO:1901001"},{"relation_name":"negatively_regulates","term_name":"cellular hyperosmotic salinity response","termid":"GO:0071475"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of cellular hyperosmotic salinity response","synonyms":[{"name":"down regulation of cellular hyperosmotic salinity response","type":"related"},{"name":"down regulation of cellular response to hyperosmotic salt stress","type":"exact"},{"name":"down-regulation of cellular hyperosmotic salinity response","type":"related"},{"name":"down-regulation of cellular response to hyperosmotic salt stress","type":"exact"},{"name":"downregulation of cellular hyperosmotic salinity response","type":"related"},{"name":"downregulation of cellular response to hyperosmotic salt stress","type":"exact"},{"name":"inhibition of cellular hyperosmotic salinity response","type":"narrow"},{"name":"inhibition of cellular response to hyperosmotic salt stress","type":"narrow"},{"name":"negative regulation of cellular response to hyperosmotic salt stress","type":"exact"}],"termid":"GO:1900070"}


id: PBO:0033808
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_DNA_recombination_at_telomere_during_vegetative_growth","termid":"PBO:0033808"}


id: MONDO:1011875
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"nervous system disorder, non-human animal","termid":"MONDO:1011336"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"progressive ataxia with head tremor and seizures, non-human animal","secondary_identifiers":["OMIA:001363"],"termid":"MONDO:1011875","xrefs":{"Monarch":{"xref_id":"1011875"}}}


id: FYPO:0005115
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is elongated and has an abnormal shape featuring a constriction at the center of the cell, corresponding to the cell division site. In some such cells, the diameter at the ends is much greater than in wild-type cells.","definition_xrefs":["PomBase:mah","PomBase:vw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"elongated vegetative cell","termid":"FYPO:0001122"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000005"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"has_part","termid":"FYPO:0001320"},{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"has_part","termid":"FYPO:0000005"}],"interesting_parent_ids":["FYPO:0000005","FYPO:0001985","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"elongated vegetative cell with central constriction","synonyms":[{"name":"cell morphology, elongated dumbbell","type":"related"},{"name":"cell morphology, long dumbbell","type":"related"},{"name":"elongated cell with central constriction during mitotic cell cycle","type":"related"},{"name":"elongated cell with central constriction during vegetative growth","type":"exact"},{"name":"elongated dumbbell morphology","type":"related"},{"name":"elongated dumbbell-shaped vegetative cell","type":"related"},{"name":"elongated swollen vegetative cell with constricted region at cell division site","type":"exact"}],"termid":"FYPO:0005115"}


id: PBO:0111794
data:
  {"annotation_feature_type":"gene","cv_name":"pombase_family_or_domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cyclin","termid":"PBO:0111794"}


id: GO:0006420
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process of coupling arginine to arginyl-tRNA, catalyzed by arginyl-tRNA synthetase. The arginyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of an alanine accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.","definition_xrefs":["GOC:mcc","ISBN:0716730510"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tRNA aminoacylation for protein translation","termid":"GO:0006418"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0006520"},{"rel_name":"is_a","termid":"GO:0006399"}],"interesting_parent_ids":["GO:0010467","GO:0008150","GO:0006520","GO:0006399"],"is_obsolete":false,"name":"arginyl-tRNA aminoacylation","termid":"GO:0006420"}


id: PBO:0082505
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Catalytic subunit of mitochondrial inner membrane peptidase complex; required for maturation of mitochondrial proteins of the intermembrane space; complex contains two catalytic subunits (Imp1p and Imp2p that differ in substrate specificity), and Som1p","termid":"PBO:0082505"}


id: PR:O13965
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mug70 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O13965"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiotically up-regulated gene 70 protein (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC24C9.05c","synonyms":[{"name":"Spom972h-mug70","type":"exact"}],"termid":"PR:O13965"}


id: GO:0102864
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 1-18:3-2-18:2-phosphatidylcholine + O2 + a reduced electron acceptor = 1-18:3-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete 1-18:3-2-18:2-phosphatidylcholine desaturase activity (obsolete GO:0102864)","termid":"GO:0102864"}


id: FYPO:0002260
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which L-glutamate import into the cell is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal amino acid import","termid":"FYPO:0001596"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000138"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0000002","FYPO:0001320","FYPO:0000138","FYPO:0001312"],"is_obsolete":false,"name":"normal glutamate import","synonyms":[{"name":"normal L-glutamate import across plasma membrane","type":"exact"},{"name":"normal L-glutamic acid import","type":"exact"},{"name":"normal glutamate import during mitotic cell cycle","type":"related"},{"name":"normal glutamate import during vegetative growth","type":"exact"},{"name":"normal glutamate import into cell","type":"exact"},{"name":"normal glutamate uptake","type":"exact"},{"name":"normal glutamic acid import","type":"exact"}],"termid":"FYPO:0002260"}


id: MONDO:0011721
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"qualitative or quantitative defects of dysferlin","termid":"MONDO:0016145"},{"relation_name":"is_a","term_name":"distal myopathy","termid":"MONDO:0018949"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0005336"],"is_obsolete":false,"name":"distal myopathy with anterior tibial onset","secondary_identifiers":["UMLS:C1847532","GARD:17080","Orphanet:178400","DOID:0111187","icd11.foundation:651559966","MEDGEN:335706","MESH:C564664","OMIM:606768"],"synonyms":[{"name":"DMAT","type":"related"},{"name":"distal anterior compartment myopathy","type":"exact"},{"name":"myopathy, distal, with anterior tibial onset","type":"related"}],"termid":"MONDO:0011721","xrefs":{"Monarch":{"xref_id":"0011721"}}}


id: FYPO:0001685
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to purvalanol A is higher than normal. Total RNA or a specific RNA may be affected.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased RNA level during vegetative growth","termid":"FYPO:0000825"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001985","FYPO:0005447","FYPO:0001320","FYPO:0006551"],"is_obsolete":false,"name":"increased RNA level during cellular response to purvalanol A","synonyms":[{"name":"increased RNA accumulation during cellular response to purvalanol A","type":"related"},{"name":"increased RNA level during cellular response to purvalanol A during mitotic cell cycle","type":"related"},{"name":"increased RNA level during cellular response to purvalanol A during vegetative growth","type":"exact"},{"name":"increased mRNA level during cellular response to purvalanol A","type":"narrow"},{"name":"increased transcript level during cellular response to purvalanol A","type":"exact"}],"termid":"FYPO:0001685"}


id: MONDO:0019877
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Distal trisomy 2q is a rare chromosomal anomaly, resulting from the partial duplication of the long arm of chromosome 2, characterized by moderate psychomotor delay, mild intellectual disability, facial dysmorphism (high hairline, prominent forehead, hypertelorism, upslanting palpebral fissures, large, low-set and/or posteriorly rotated ears, depressed/broad nasal bridge, prominent nasal tip, thin upper lip vermillion), clino-/camptodactyly and normal or increased body measurements. On occasion genital anomalies (hypospadias, cryptorchidism, shawl scrotum) and short stature may be observed.","definition_xrefs":["Orphanet:96094"],"direct_ancestors":[{"relation_name":"is_a","term_name":"partial duplication of the long arm of chromosome 2","termid":"MONDO:0016953"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"distal trisomy 2q","secondary_identifiers":["SCTID:763272003","MEDGEN:1634043","GARD:19310","UMLS:C4706361"],"synonyms":[{"name":"distal duplication 2q","type":"exact"},{"name":"distal trisomy type 2q","type":"exact"},{"name":"telomeric duplication 2q","type":"exact"},{"name":"trisomy 2qter","type":"exact"}],"termid":"MONDO:0019877","xrefs":{"Monarch":{"xref_id":"0019877"}}}


id: PBO:0028695
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_transcription_termination","termid":"PBO:0028695"}


id: GO:0071319
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzoic acid stimulus.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to benzoic acid","termid":"GO:0080021"},{"relation_name":"is_a","term_name":"cellular response to oxygen-containing compound","termid":"GO:1901701"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to benzoic acid","termid":"GO:0071319"}


id: PBO:0078494
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Ile (anticodon GAT) 1-1","termid":"PBO:0078494"}


id: PBO:0046977
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 86 member B3, pseudogene","termid":"PBO:0046977"}


id: SO:1000081
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A mutation that alters the rate a which transcription of the sequence occurs.","definition_xrefs":["SO:ke"],"gene_count":0,"genotype_count":0,"name":"OBSOLETE SO:1000081 sequence_variant_affecting_rate_of_transcription (obsolete SO:1000081)","synonyms":[{"name":"mutation affecting rate of transcription","type":"related"},{"name":"sequence variant affecting rate of transcription","type":"exact"}],"termid":"SO:1000081"}


id: PBO:0062678
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 14 subfamily K member 1","termid":"PBO:0062678"}


id: MONDO:0859276
data:
  {"annotated_genes":["SJAG_04994"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87649],"is_not":false,"summary":null,"term":"MONDO:0859276"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04994":null},"genotype_count":0,"is_obsolete":false,"name":"primordial dwarfism-immunodeficiency-lipodystrophy syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:620005","UMLS:C5774198","MEDGEN:1823971"],"termid":"MONDO:0859276","terms_by_termid":{"MONDO:0859276":null},"xrefs":{"Monarch":{"xref_id":"0859276"}}}


id: PBO:0091822
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Arf3/6 docking factor","termid":"PBO:0091822"}


id: PBO:0017048
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Schizosaccharomyces specific protein Mug45","termid":"PBO:0017048"}


id: PBO:0027959
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_catalase_activity_during_cellular_response_to_nitrosative_stress","termid":"PBO:0027959"}


id: GO:0032165
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"Arrays of septin filaments, or bars, found in a series of filamentous structures; observed in the prospore membrane during spore formation.","definition_xrefs":["GOC:krc","PMID:16151244"],"direct_ancestors":[{"relation_name":"is_a","term_name":"septin filament array","termid":"GO:0032160"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"prospore septin filament array","termid":"GO:0032165"}


id: MONDO:0007268
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An autosomal dominant condition caused by mutation(s) in the MYBPC3 gene, encoding MYBPC3 protein. It is characterized by severe neonatal hypertrophic cardiomyopathy.","definition_xrefs":["NCIT:C133725"],"direct_ancestors":[{"relation_name":"is_a","term_name":"familial hypertrophic cardiomyopathy","termid":"MONDO:0024573"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"hypertrophic cardiomyopathy 4","secondary_identifiers":["DOID:0110310","MESH:C566169","OMIM:115197","UMLS:C1861862","MEDGEN:350526"],"synonyms":[{"name":"CMH4","type":"exact"},{"name":"MYBPC3 hypertrophic cardiomyopathy","type":"exact"},{"name":"cardiomyopathy, familial hypertrophic, 4","type":"exact"},{"name":"cardiomyopathy, familial hypertrophic, 4, susceptibility to","type":"related"},{"name":"cardiomyopathy, familial hypertrophic, type 4","type":"exact"},{"name":"cardiomyopathy, hypertrophic, 4","type":"exact"},{"name":"familial hypertrophic cardiomyopathy type 4","type":"exact"},{"name":"hypertrophic cardiomyopathy 4","type":"exact"},{"name":"hypertrophic cardiomyopathy caused by mutation in MYBPC3","type":"exact"},{"name":"hypertrophic cardiomyopathy type 4","type":"exact"}],"termid":"MONDO:0007268","xrefs":{"Monarch":{"xref_id":"0007268"}}}


id: FYPO:0001951
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the export of calcium ions out of a cell is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal transport during vegetative growth","termid":"FYPO:0005973"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0005447","FYPO:0000138","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"abnormal calcium export","synonyms":[{"name":"abnormal calcium efflux from cell","type":"exact"},{"name":"abnormal calcium export during mitotic cell cycle","type":"related"},{"name":"abnormal calcium export during vegetative growth","type":"exact"},{"name":"abnormal calcium export from cell","type":"narrow"},{"name":"abnormal calcium ion export","type":"exact"},{"name":"abnormal calcium ion export from cell","type":"exact"},{"name":"abnormal cellular calcium export","type":"exact"}],"termid":"FYPO:0001951"}


id: PBO:0059507
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrially encoded cytochrome c oxidase III","termid":"PBO:0059507"}


id: MONDO:0004627
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Acute or chronic inflammation of the duodenum. Causes include bacterial and viral infections and gastroesophageal reflux disease. Symptoms include vomiting and abdominal pain.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"duodenal disorder","termid":"MONDO:0002866"},{"relation_name":"is_a","term_name":"enteritis","termid":"MONDO:0043579"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"duodenitis","secondary_identifiers":["NCIT:C94409","UMLS:C0013298","ICD9:535.6","SCTID:72007001","ICD10CM:K29.8","MESH:D004382","DOID:8643","icd11.foundation:1595026136","ICD9:535.60","MEDGEN:4419"],"synonyms":[{"name":"duodenitis","type":"exact"},{"name":"duodenum inflammation","type":"exact"},{"name":"hemorrhagic duodenitis","type":"narrow"},{"name":"inflammation of duodenum","type":"exact"}],"termid":"MONDO:0004627","xrefs":{"Monarch":{"xref_id":"0004627"}}}


id: GO:0000025
data:
  {"annotated_genes":["SJAG_02131","SJAG_03824"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[103416,103417],"is_not":false,"summary":null,"term":"GO:0000025"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose).","definition_xrefs":["GOC:jl","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"maltose metabolic process","termid":"GO:0000023"},{"relation_name":"is_a","term_name":"disaccharide catabolic process","termid":"GO:0046352"}],"gene_count":2,"genes_by_uniquename":{"SJAG_02131":null,"SJAG_03824":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0005975"],"is_obsolete":false,"name":"maltose catabolic process","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["MetaCyc:MALTOSECAT-PWY"],"synonyms":[{"name":"malt sugar catabolic process","type":"exact"},{"name":"malt sugar catabolism","type":"exact"},{"name":"maltose breakdown","type":"exact"},{"name":"maltose degradation","type":"exact"},{"name":"maltose hydrolysis","type":"narrow"}],"termid":"GO:0000025","terms_by_termid":{"GO:0000025":null}}


id: GO:0031884
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a type 1 member 1 taste receptor.","definition_xrefs":["GOC:nln","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"taste receptor binding","termid":"GO:0031883"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0005488","GO:0005515","GO:0003674"],"is_obsolete":false,"name":"type 1 member 1 taste receptor binding","synonyms":[{"name":"type 1 member 1 taste receptor ligand","type":"narrow"}],"termid":"GO:0031884"}


id: GO:0090686
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transmembrane transfer of a monoatomic cation by a channel that opens when glycine betaine has been bound by the channel complex or one of its constituent parts.","definition_xrefs":["PMID:24212673","GOC:kmv"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ligand-gated monoatomic cation channel activity","termid":"GO:0099094"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0022857","GO:0003674","GO:0005215"],"is_obsolete":false,"name":"glycine betaine-activated nonselective monoatomic cation channel activity","synonyms":[{"name":"glycine betaine-activated nonselective monovalent cation channel activity","type":"related"}],"termid":"GO:0090686"}


id: GO:0006035
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways resulting in the formation of cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles.","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete cuticle chitin biosynthetic process (obsolete GO:0006035)","synonyms":[{"name":"cuticle chitin anabolism","type":"exact"},{"name":"cuticle chitin biosynthesis","type":"exact"},{"name":"cuticle chitin formation","type":"exact"},{"name":"cuticle chitin synthesis","type":"exact"}],"termid":"GO:0006035"}


id: PBO:0084543
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication","termid":"PBO:0084543"}


id: PBO:0049240
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glutamate metabotropic receptor 8","termid":"PBO:0049240"}


id: GO:0061060
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of immune system process","termid":"GO:0002683"},{"relation_name":"is_a","term_name":"negative regulation of signal transduction","termid":"GO:0009968"},{"relation_name":"is_a","term_name":"regulation of peptidoglycan recognition protein signaling pathway","termid":"GO:0061058"},{"relation_name":"is_a","term_name":"negative regulation of defense response to bacterium","termid":"GO:1900425"},{"relation_name":"negatively_regulates","term_name":"peptidoglycan recognition protein signaling pathway","termid":"GO:0061057"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"negative regulation of peptidoglycan recognition protein signaling pathway","synonyms":[{"name":"negative regulation of peptidoglycan recognition protein signalling pathway","type":"exact"}],"termid":"GO:0061060"}


id: PBO:0069603
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 880, pseudogene","termid":"PBO:0069603"}


id: PBO:0001984
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glycerophosphoryl diester phosphodiesterase Gde1 (predicted)","termid":"PBO:0001984"}


id: MONDO:0019763
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Laryngo-tracheo-esophageal cleft (LC) type 3 is a congenital respiratory tract anomaly characterized by a cleft extending through the cricoid cartilage, sometimes into the cervical trachea, with severe swallowing disorders, lung infections and pulmonary damage.","definition_xrefs":["Orphanet:93940"],"direct_ancestors":[{"relation_name":"is_a","term_name":"laryngotracheoesophageal cleft","termid":"MONDO:0016060"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"laryngotracheoesophageal cleft type 3","secondary_identifiers":["GARD:16833","MEDGEN:667241","UMLS:C0584825"],"synonyms":[{"name":"LTEC III","type":"exact"},{"name":"LTEC3","type":"exact"},{"name":"laryngo-tracheo-esophageal cleft type 3","type":"exact"}],"termid":"MONDO:0019763","xrefs":{"Monarch":{"xref_id":"0019763"}}}


id: PBO:0046432
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"epoxide hydrolase 2","termid":"PBO:0046432"}


id: GO:0051367
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The decanoylation of peptidyl-serine to form peptidyl-O3-decanoyl-L-serine, typical of the protein ghrelin.","definition_xrefs":["PMID:12630926","RESID:AA0385","GOC:jsg"],"gene_count":0,"genotype_count":0,"name":"obsolete peptidyl-serine decanoylation (obsolete GO:0051367)","termid":"GO:0051367"}


id: PBO:0005708
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA-directed RNA polymerase III complex subunit Rpc53 (predicted)","termid":"PBO:0005708"}


id: GO:0035757
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to chemokine (C-C motif) ligand 19.","definition_xrefs":["GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"C-C chemokine binding","termid":"GO:0019957"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005515","GO:0005488","GO:0003674"],"is_obsolete":false,"name":"chemokine (C-C motif) ligand 19 binding","synonyms":[{"name":"CCL19 binding","type":"exact"}],"termid":"GO:0035757"}


id: PBO:0044618
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"discoidin, CUB and LCCL domain containing 1","termid":"PBO:0044618"}


id: PBO:0073912
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 16 member 3","termid":"PBO:0073912"}


id: PBO:0113413
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ribosome-associated protein; involved along with heterodimeric partner Tma20p in recycling of 40S ribosomal subunits; involved in nonsense-mediated mRNA decay (NMD); contains a putative RNA binding domain; localizes to the cytoplasm in HTP studies; similar to human GRAP and human DRP1, which interacts with human Tma20p homolog MCT-1; protein abundance increases in response to DNA replication stress","termid":"PBO:0113413"}


id: PBO:0005127
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"malate dehydrogenase (predicted)","termid":"PBO:0005127"}


id: PBO:0054889
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2303","termid":"PBO:0054889"}


id: PBO:0058085
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4302","termid":"PBO:0058085"}


id: MONDO:0007121
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aniridia, microcornea, and spontaneously Reabsorbed cataract","secondary_identifiers":["MEDGEN:350777","MESH:C566280","OMIM:106230","UMLS:C1862867"],"synonyms":[{"name":"aniridia, microcornea, and spontaneously Reabsorbed cataract","type":"exact"}],"termid":"MONDO:0007121","xrefs":{"Monarch":{"xref_id":"0007121"}}}


id: PBO:0040363
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP synthase peripheral stalk-membrane subunit b","termid":"PBO:0040363"}


id: MONDO:0015566
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"2q24 microdeletion syndrome is a chromosomal anomaly consisting of a partial long arm deletion of chromosome 2 and characterized clinically by a wide range of manifestations (depending on the specific region deleted) which can include seizures, microcephaly, dysmorphic features, cleft palate, eye abnormalities (coloboma, cataract and microphthalmia), growth retardation, failure to thrive, heart defects, limb anomalies, developmental delay and autism.","definition_xrefs":["Orphanet:1617"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete chromosomal anomaly with cataract (obsolete MONDO:0020226)","termid":"MONDO:0020226"},{"relation_name":"is_a","term_name":"partial deletion of the long arm of chromosome 2","termid":"MONDO:0016901"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2q24 microdeletion syndrome","secondary_identifiers":["GARD:3746","MEDGEN:419168","SCTID:719658006","UMLS:C2931816","MESH:C538316"],"synonyms":[{"name":"2q24 deletion","type":"related"},{"name":"Del(2)(q24)","type":"exact"},{"name":"chromosome 2q24 microdeletion syndrome","type":"related"},{"name":"deletion 2q24","type":"related"},{"name":"monosomy 2q24","type":"exact"}],"termid":"MONDO:0015566","xrefs":{"Monarch":{"xref_id":"0015566"}}}


id: GO:0001847
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with an opsonin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.","definition_xrefs":["GOC:signaling","GOC:add","ISBN:0781735149"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transmembrane signaling receptor activity","termid":"GO:0004888"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0038023"}],"interesting_parent_ids":["GO:0003674","GO:0038023"],"is_obsolete":false,"name":"opsonin receptor activity","termid":"GO:0001847"}


id: PBO:0003721
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin C-terminal hydrolase Ubp11","termid":"PBO:0003721"}


id: FYPO:0003052
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is abnormal at a cis-acting homologous chromosome pairing region such as the sme2 locus.","definition_xrefs":["PMID:22582262","PMID:24173580","PomBase:mah","PMID:23117617"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal homologous chromosome pairing","termid":"FYPO:0003024"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000641"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"part_of","termid":"FYPO:0000631"},{"rel_name":"part_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"part_of","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0000631","FYPO:0000002","FYPO:0001985","FYPO:0000641","FYPO:0005447"],"is_obsolete":false,"name":"abnormal homologous chromosome pairing at cis-acting homologous chromosome pairing region","synonyms":[{"name":"abnormal homologous chromosome pairing at meiosis at cis-acting homologous chromosome pairing region","type":"exact"},{"name":"abnormal homologous chromosome pairing at sme2 locus","type":"narrow"},{"name":"abnormal synapsis at cis-acting homologous chromosome pairing region","type":"exact"}],"termid":"FYPO:0003052"}


id: MONDO:1012134
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"immunoglobulin G2 deficiency, non-human animal","termid":"MONDO:1011728"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin G2 deficiency, cattle","secondary_identifiers":["OMIA:000555-9913"],"termid":"MONDO:1012134","xrefs":{"Monarch":{"xref_id":"1012134"}}}


id: GO:0015708
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of silicates from outside of a cell, across the plasma membrane and into the cytosol. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates.","definition_xrefs":["GOC:krc","GOC:ai","PMID:16572174"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inorganic anion import across plasma membrane","termid":"GO:0098658"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0055085"}],"interesting_parent_ids":["GO:0006810","GO:0008150","GO:0051179","GO:0055085"],"is_obsolete":false,"name":"silicic acid import across plasma membrane","secondary_identifiers":["GO:0051207","GO:1902067"],"synonyms":[{"name":"silicate transport","type":"broad"},{"name":"silicic acid import","type":"related"},{"name":"silicic acid transport","type":"exact"},{"name":"silicon uptake","type":"related"}],"termid":"GO:0015708"}


id: PR:O60085
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A methionine aminopeptidase 2 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO03176"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"methionine aminopeptidase 2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC14C8.03","secondary_identifiers":["UniProtKB:O60085"],"synonyms":[{"name":"MAP 2 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"MetAP 2 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-METAP2","type":"exact"},{"name":"peptidase M (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O60085"}


id: GO:1901277
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of tartrate.","definition_xrefs":["UniPathway:UPA00839","GOC:yaf","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"biosynthetic process","termid":"GO:0009058"},{"relation_name":"is_a","term_name":"tartrate metabolic process","termid":"GO:1901275"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"tartrate biosynthetic process","synonyms":[{"name":"tartrate anabolism","type":"exact"},{"name":"tartrate biosynthesis","type":"exact"},{"name":"tartrate formation","type":"exact"},{"name":"tartrate synthesis","type":"exact"}],"termid":"GO:1901277"}


id: GO:1990900
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A constriction site at the junction of the plasma, flagellar and flagellar pocket membranes where the flagellum emerges from the cell body. Observed in some unicellular eukaryotic species such as Chlamydomonas, Giardia and Trypanosoma.","definition_xrefs":["PMID:19806154","PMID:18462016","GOC:giardia"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"ciliary pocket","termid":"GO:0020016"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"ciliary pocket collar","synonyms":[{"name":"FPC","type":"related"},{"name":"cilium pocket collar","type":"exact"},{"name":"flagellar collar","type":"related"},{"name":"flagellar pocket collar","type":"exact"},{"name":"flagellar pore","type":"related"},{"name":"flagellum pocket collar","type":"exact"}],"termid":"GO:1990900"}


id: MONDO:0060659
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Mendelian neurodevelopmental disorder","termid":"MONDO:0100500"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0700092"}],"interesting_parent_ids":["MONDO:0700092"],"is_obsolete":false,"name":"neurodevelopmental disorder with poor language and loss of hand skills","secondary_identifiers":["OMIM:617903","MEDGEN:1637031","UMLS:C4693546"],"synonyms":[{"name":"NDPLHS","type":"related"},{"name":"neurodevelopmental disorder with poor language and loss of hand skills","type":"exact"}],"termid":"MONDO:0060659","xrefs":{"Monarch":{"xref_id":"0060659"}}}


id: MONDO:0006927
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Infections with bacteria of the family rickettsiaceae.","definition_xrefs":["MESH:D012288"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Rickettsiosis","termid":"MONDO:0006956"},{"relation_name":"is_a","term_name":"gram-negative bacterial infections","termid":"MONDO:0021678"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rickettsiaceae infectious disease","secondary_identifiers":["EFO:1001128"],"synonyms":[{"name":"Rickettsiaceae caused disease or disorder","type":"exact"},{"name":"Rickettsiaceae disease or disorder","type":"exact"},{"name":"Rickettsiaceae infection","type":"related"},{"name":"infection, Rickettsiaceae","type":"related"},{"name":"infections, Rickettsiaceae","type":"related"},{"name":"rickettsialpox","type":"related"}],"termid":"MONDO:0006927","xrefs":{"Monarch":{"xref_id":"0006927"}}}


id: PBO:0059525
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrially encoded light strand origin of replication","termid":"PBO:0059525"}


id: GO:0002211
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A behavioral response seeking to protect an organism from an a perceived external threat from an insect or insects to that organism.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"behavioral defense response","termid":"GO:0002209"},{"relation_name":"is_a","term_name":"defense response to insect","termid":"GO:0002213"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"behavioral defense response to insect","synonyms":[{"name":"behavioural defense response to insect","type":"exact"}],"termid":"GO:0002211"}


id: PATO:0000093
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000093 chemical sensitivity (obsolete PATO:0000093)","termid":"PATO:0000093"}


id: RO:0002595
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity.","direct_ancestors":[{"relation_name":"is_a","term_name":"causally_related_to","termid":"RO:0002410"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"causal_relation_between_material_entity_and_a_process","termid":"RO:0002595"}


id: MONDO:0850098
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A form of male infertility that is characterized by a combination of low number or oligozoospermia, poor motility or asthenozoospermia, and abnormal shape or teratozoospermia of sperms. OAT is the most common cause of male subfertility.","definition_xrefs":["DOID:0070311"],"direct_ancestors":[{"relation_name":"is_a","term_name":"male infertility","termid":"MONDO:0005372"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005047"}],"interesting_parent_ids":["MONDO:0005047"],"is_obsolete":false,"name":"oligoasthenoteratozoospermia","termid":"MONDO:0850098","xrefs":{"Monarch":{"xref_id":"0850098"}}}


id: PBO:0002460
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"40S ribosomal protein S28 (predicted)","termid":"PBO:0002460"}


id: PBO:0039071
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"argonaute RISC catalytic component 3","termid":"PBO:0039071"}


id: GO:0032425
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of mismatch repair.","definition_xrefs":["GOC:vk"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of mismatch repair","termid":"GO:0032423"},{"relation_name":"is_a","term_name":"positive regulation of DNA repair","termid":"GO:0045739"},{"relation_name":"positively_regulates","term_name":"mismatch repair","termid":"GO:0006298"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0006259"},{"rel_name":"positively_regulates","termid":"GO:0006281"},{"rel_name":"regulates","termid":"GO:0006259"},{"rel_name":"regulates","termid":"GO:0006281"}],"interesting_parent_ids":["GO:0006259","GO:0006281","GO:0008150"],"is_obsolete":false,"name":"positive regulation of mismatch repair","synonyms":[{"name":"activation of mismatch repair","type":"narrow"},{"name":"stimulation of mismatch repair","type":"narrow"},{"name":"up regulation of mismatch repair","type":"exact"},{"name":"up-regulation of mismatch repair","type":"exact"},{"name":"upregulation of mismatch repair","type":"exact"}],"termid":"GO:0032425"}


id: PBO:0083938
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Galactose permease; required for utilization of galactose; also able to transport glucose","termid":"PBO:0083938"}


id: PBO:0045819
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"eukaryotic translation elongation factor 1 alpha 1 pseudogene 9","termid":"PBO:0045819"}


id: PBO:0087885
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Transcriptional repressor, activator; role in cellular adjustment to osmotic stress including modulation of mating efficiency; involved in repression of subset of hypoxic genes by Rox1p, repression of several DAN/TIR genes during aerobic growth, ergosterol biosynthetic genes in response to hyperosmotic stress; contributes to recruitment of Tup1p-Cyc8p general repressor to promoters; relocalizes to cytosol under hypoxia; forms [MOT3+] prion under anaerobic conditions","termid":"PBO:0087885"}


id: PBO:0071940
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S4X pseudogene 17","termid":"PBO:0071940"}


id: PBO:0082861
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Core Sm protein Sm B; part of heteroheptameric complex (with Smd1p, Smd2p, Smd3p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm B and Sm B'","termid":"PBO:0082861"}


id: GO:0052217
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen on, within or near a second organism, where the two organisms are in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"gene_count":0,"genotype_count":0,"name":"obsolete aerotaxis in environment of other organism involved in symbiotic interaction (obsolete GO:0052217)","synonyms":[{"name":"aerotaxis in environment of other organism during symbiotic interaction","type":"related"},{"name":"aerotaxis in response to environment of other organism","type":"exact"}],"termid":"GO:0052217"}


id: MONDO:0019828
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Pituitary stalk interruption syndrome (PSIS) is a congenital abnormality of the pituitary that is responsible for pituitary deficiency and is usually characterized by the triad of a very thin or interrupted pituitary stalk, an ectopic (or absent) posterior pituitary (EPP) and hypoplasia or aplasia of the anterior pituitary visible on MRI. In some patients the abnormality may be limited to EPP (also called ectopic neurohypophysis) or to an interrupted pituitary stalk.","definition_xrefs":["Orphanet:95496"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"non-acquired pituitary hormone deficiency","termid":"MONDO:0019824"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pituitary stalk interruption syndrome","secondary_identifiers":["SCTID:715727009","MEDGEN:883774","GARD:13209","icd11.foundation:1474283222","NCIT:C121150","UMLS:C4053775"],"synonyms":[{"name":"PSIS","type":"exact"},{"name":"ectopic neurohypophysis","type":"exact"},{"name":"hypoplastic anterior pituitary, missing stalk, and ectopic posterior pituitary","type":"exact"}],"termid":"MONDO:0019828","xrefs":{"Monarch":{"xref_id":"0019828"}}}


id: MONDO:0012762
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any catecholaminergic polymorphic ventricular tachycardia in which the cause of the disease is a mutation in the CASQ2 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"catecholaminergic polymorphic ventricular tachycardia","termid":"MONDO:0017990"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"catecholaminergic polymorphic ventricular tachycardia 2","secondary_identifiers":["GARD:15535","ICD10CM:I47.2","MEDGEN:393837","DOID:0060676","NCIT:C148368","OMIM:611938","UMLS:C2677794"],"synonyms":[{"name":"CASQ2 catecholaminergic polymorphic ventricular tachycardia","type":"exact"},{"name":"CPVT2","type":"related"},{"name":"CVPT2","type":"exact"},{"name":"catecholaminergic polymorphic ventricular tachycardia 2","type":"exact"},{"name":"catecholaminergic polymorphic ventricular tachycardia caused by mutation in CASQ2","type":"exact"},{"name":"catecholaminergic polymorphic ventricular tachycardia type 2","type":"exact"},{"name":"ventricular tachycardia, catecholaminergic polymorphic, 2","type":"related"},{"name":"ventricular tachycardia, catecholaminergic polymorphic, type 2","type":"exact"},{"name":"ventricular tachycardia, stress-induced polymorphic","type":"related"}],"termid":"MONDO:0012762","xrefs":{"Monarch":{"xref_id":"0012762"}}}


id: PATO:0001187
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A maturity quality inhering in a insect by virtue of the bearer's being in the chrysalis (cocoon) or post larval stage.","definition_xrefs":["WordNet:WordNet"],"direct_ancestors":[{"relation_name":"is_a","term_name":"maturity","termid":"PATO:0000261"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pupal","termid":"PATO:0001187"}


id: GO:0030514
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of BMP signaling pathway","termid":"GO:0030510"},{"relation_name":"is_a","term_name":"negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway","termid":"GO:0090101"},{"relation_name":"is_a","term_name":"negative regulation of cellular response to growth factor stimulus","termid":"GO:0090288"},{"relation_name":"negatively_regulates","term_name":"BMP signaling pathway","termid":"GO:0030509"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"negative regulation of BMP signaling pathway","secondary_identifiers":["GO:0090099"],"synonyms":[{"name":"down regulation of BMP signaling pathway","type":"exact"},{"name":"down-regulation of BMP signaling pathway","type":"exact"},{"name":"downregulation of BMP signaling pathway","type":"exact"},{"name":"inhibition of BMP signaling pathway","type":"narrow"},{"name":"negative regulation of BMP receptor signaling pathway","type":"related"},{"name":"negative regulation of BMP signalling pathway","type":"exact"},{"name":"negative regulation of bone morphogenetic protein signaling pathway","type":"exact"},{"name":"negative regulation of bone morphogenetic protein signalling pathway","type":"exact"},{"name":"negative regulation of decapentaplegic receptor signaling pathway","type":"narrow"},{"name":"negative regulation of decapentaplegic receptor signalling pathway","type":"narrow"},{"name":"negative regulation of decapentaplegic signaling pathway","type":"narrow"}],"termid":"GO:0030514"}


id: PBO:0079289
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TTLL7 intronic transcript 1","termid":"PBO:0079289"}


id: PBO:0051792
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"IQCH antisense RNA 1","termid":"PBO:0051792"}


id: PR:O59705
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- cog2 gene.","definition_xrefs":["UniProtKB:O59705","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"conserved oligomeric Golgi complex subunit 2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC36.08c","synonyms":[{"name":"COG complex subunit 2 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-cog2","type":"exact"},{"name":"component of oligomeric Golgi complex 2 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O59705"}


id: MONDO:0004326
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign neoplasm that arises from the ciliated respiratory mucosa that lines the sphenoid sinus. It results from the invagination and proliferation of epithelial cells in the underlying stroma.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inverted papilloma","termid":"MONDO:0002537"},{"relation_name":"is_a","term_name":"sphenoid sinus Schneiderian papilloma","termid":"MONDO:0004327"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sphenoid sinus inverted papilloma","secondary_identifiers":["MEDGEN:236834","DOID:7678","UMLS:C1336037","NCIT:C6841"],"synonyms":[{"name":"inverted papilloma of sphenoid sinus","type":"exact"},{"name":"inverted papilloma of the sphenoid sinus","type":"exact"},{"name":"sphenoidal sinus inverted papilloma","type":"exact"}],"termid":"MONDO:0004326","xrefs":{"Monarch":{"xref_id":"0004326"}}}


id: MONDO:0043759
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Ectopic pregnancy characterized by the implantation of the embryo in the peritoneal cavity or abdominal organs.","definition_xrefs":["NCIT:C92921"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ectopic pregnancy","termid":"MONDO:0000755"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"abdominal ectopic pregnancy","secondary_identifiers":["MESH:D011269","UMLS:C0032984","MEDGEN:46072","SCTID:82661006"],"synonyms":[{"name":"Pregnancies, abdominal","type":"related"},{"name":"abdomen ectopic pregnancy","type":"exact"},{"name":"abdominal Pregnancies","type":"related"},{"name":"abdominal pregnancy","type":"exact"},{"name":"ectopic pregnancy of abdomen","type":"exact"},{"name":"intra-abdominal pregnancy","type":"exact"}],"termid":"MONDO:0043759","xrefs":{"Monarch":{"xref_id":"0043759"}}}


id: PBO:0088490
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3,4-dihydroxy-2-butanone 4-phosphate synthase Rib3","termid":"PBO:0088490"}


id: PBO:0063808
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphorylase kinase catalytic subunit gamma 1","termid":"PBO:0063808"}


id: GO:0030255
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which proteins are transferred into the extracellular milieu or directly into host cells, via the type IV protein secretion system.","definition_xrefs":["GOC:pamgo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein secretion","termid":"GO:0009306"},{"relation_name":"is_a","term_name":"secretion by the type IV secretion system","termid":"GO:0044097"},{"relation_name":"is_a","term_name":"protein transmembrane transport","termid":"GO:0071806"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0055085","GO:0008150","GO:0051179","GO:0006810"],"is_obsolete":false,"name":"protein secretion by the type IV secretion system","synonyms":[{"name":"protein secretion by the T4SS","type":"exact"},{"name":"protein secretion by the type IV protein secretion system","type":"exact"},{"name":"type IV protein secretion system","type":"narrow"}],"termid":"GO:0030255"}


id: PBO:0078376
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"triggering receptor expressed on myeloid cells 2","termid":"PBO:0078376"}


id: PBO:0074473
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"smoothelin like 2","termid":"PBO:0074473"}


id: FYPO:0000980
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing amphotericin B.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal vegetative cell population growth","termid":"FYPO:0001357"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0000139","FYPO:0002060","FYPO:0002057","FYPO:0000003","FYPO:0002058"],"is_obsolete":false,"name":"normal growth on amphotericin B","synonyms":[{"name":"normal cell population growth on amphotericin B","type":"exact"},{"name":"normal vegetative cell population growth on amphotericin B","type":"exact"}],"termid":"FYPO:0000980"}


id: MONDO:0011030
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"epithelial basolateral chloride conductance regulator, rabbit, homolog of","secondary_identifiers":["MEDGEN:321967","OMIM:601315","UMLS:C1832477"],"synonyms":[{"name":"Ebcr","type":"related"},{"name":"epithelial basolateral chloride conductance regulator, rabbit, homolog of","type":"exact"}],"termid":"MONDO:0011030","xrefs":{"Monarch":{"xref_id":"0011030"}}}


id: PBO:0074562
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA host gene 16","termid":"PBO:0074562"}


id: PBO:0113493
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Transcription factor required for the mating response; subunit of the mRNA m6A methyltransferase (MIS) complex, regulating meiosis at multiple steps, early prior to pre-meiotic S phase and late during the completion of meiosis and sporulation; exists in two forms, a slower-migrating form abundant during vegetative growth and a faster-migrating pheromone-induced form; null mutant exhibits abnormal lipid metabolic phenotype; homologous to human METTL14, a subunit of a m6A methyltransferase complex","termid":"PBO:0113493"}


id: GO:1903863
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The aggregation, arrangement and bonding together of a set of components to form a P granule.","definition_xrefs":["GO_REF:0000079","GOC:TermGenie","PMID:25535836","GOC:kmv"],"direct_ancestors":[{"relation_name":"is_a","term_name":"P granule organization","termid":"GO:0030719"},{"relation_name":"is_a","term_name":"membraneless organelle assembly","termid":"GO:0140694"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0008150","GO:0044085"],"is_obsolete":false,"name":"P granule assembly","synonyms":[{"name":"P granule formation","type":"exact"},{"name":"germline granule assembly","type":"exact"},{"name":"germline granule formation","type":"exact"},{"name":"polar granule assembly","type":"exact"},{"name":"polar granule formation","type":"exact"}],"termid":"GO:1903863"}


id: MONDO:0003556
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare endometrial carcinoma characterized by the presence of both malignant glandular and malignant squamous cellular components.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"adenosquamous carcinoma","termid":"MONDO:0006074"},{"relation_name":"is_a","term_name":"endometrial squamous cell carcinoma","termid":"MONDO:0006198"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"endometrial adenosquamous carcinoma","secondary_identifiers":["EFO:1001952","NCIT:C114656","DOID:5631","MEDGEN:856563","UMLS:C3896969"],"synonyms":[{"name":"adenosquamous carcinoma of endometrium","type":"exact"},{"name":"adenosquamous carcinoma of the endometrium","type":"related"},{"name":"endometrial adenosquamous cancer","type":"related"},{"name":"endometrial adenosquamous carcinoma","type":"exact"},{"name":"endometrium adenosquamous carcinoma","type":"exact"}],"termid":"MONDO:0003556","xrefs":{"Monarch":{"xref_id":"0003556"}}}


id: PBO:0085500
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein arginine N-methyltransferase; exhibits septin and Hsl1p-dependent localization to the bud neck in budded cells and periodic Hsl1p-dependent phosphorylation; required with Hsl1p, and Elm1p for the mother-bud neck recruitment, phosphorylation, and degradation of Swe1p; responsible for symmetric dimethylation of histone H4 on Arg3; relocalizes away from bud neck upon DNA replication stress; human homolog PRMT5 can complement yeast hsl7 mutant","termid":"PBO:0085500"}


id: PBO:0085251
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Peripherally bound inner membrane protein of the mitochondrial matrix; involved in membrane insertion of C-terminus of Cox2p, interacts genetically and physically with Cox18p","termid":"PBO:0085251"}


id: GO:1905124
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of glucosylceramidase activity.","definition_xrefs":["GOC:PARL","GOC:TermGenie","GOC:bf","GO_REF:0000059"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of glucosylceramidase activity (obsolete GO:1905124)","synonyms":[{"name":"down regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity","type":"exact"},{"name":"down regulation of GlcCer-beta-glucosidase activity","type":"exact"},{"name":"down regulation of acid beta-glucosidase activity","type":"exact"},{"name":"down regulation of beta-D-glucocerebrosidase activity","type":"exact"},{"name":"down regulation of beta-glucocerebrosidase activity","type":"exact"},{"name":"down regulation of beta-glucosylceramidase activity","type":"exact"},{"name":"down regulation of ceramide glucosidase activity","type":"exact"},{"name":"down regulation of glucocerebrosidase activity","type":"exact"},{"name":"down regulation of glucosphingosine glucosylhydrolase activity","type":"exact"},{"name":"down regulation of glucosylceramidase activity","type":"exact"},{"name":"down regulation of glucosylcerebrosidase activity","type":"exact"},{"name":"down regulation of glucosylsphingosine beta-D-glucosidase activity","type":"exact"},{"name":"down regulation of glucosylsphingosine beta-glucosidase activity","type":"exact"},{"name":"down regulation of psychosine hydrolase activity","type":"exact"},{"name":"down-regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity","type":"exact"},{"name":"down-regulation of GlcCer-beta-glucosidase activity","type":"exact"},{"name":"down-regulation of acid beta-glucosidase activity","type":"exact"},{"name":"down-regulation of beta-D-glucocerebrosidase activity","type":"exact"},{"name":"down-regulation of beta-glucocerebrosidase activity","type":"exact"},{"name":"down-regulation of beta-glucosylceramidase activity","type":"exact"},{"name":"down-regulation of ceramide glucosidase activity","type":"exact"},{"name":"down-regulation of glucocerebrosidase activity","type":"exact"},{"name":"down-regulation of glucosphingosine glucosylhydrolase activity","type":"exact"},{"name":"down-regulation of glucosylceramidase activity","type":"exact"},{"name":"down-regulation of glucosylcerebrosidase activity","type":"exact"},{"name":"down-regulation of glucosylsphingosine beta-D-glucosidase activity","type":"exact"},{"name":"down-regulation of glucosylsphingosine beta-glucosidase activity","type":"exact"},{"name":"down-regulation of psychosine hydrolase activity","type":"exact"},{"name":"downregulation of D-glucosyl-N-acylsphingosine glucohydrolase activity","type":"exact"},{"name":"downregulation of GlcCer-beta-glucosidase activity","type":"exact"},{"name":"downregulation of acid beta-glucosidase activity","type":"exact"},{"name":"downregulation of beta-D-glucocerebrosidase activity","type":"exact"},{"name":"downregulation of beta-glucocerebrosidase activity","type":"exact"},{"name":"downregulation of beta-glucosylceramidase activity","type":"exact"},{"name":"downregulation of ceramide glucosidase activity","type":"exact"},{"name":"downregulation of glucocerebrosidase activity","type":"exact"},{"name":"downregulation of glucosphingosine glucosylhydrolase activity","type":"exact"},{"name":"downregulation of glucosylceramidase activity","type":"exact"},{"name":"downregulation of glucosylcerebrosidase activity","type":"exact"},{"name":"downregulation of glucosylsphingosine beta-D-glucosidase activity","type":"exact"},{"name":"downregulation of glucosylsphingosine beta-glucosidase activity","type":"exact"},{"name":"downregulation of psychosine hydrolase activity","type":"exact"},{"name":"inhibition of D-glucosyl-N-acylsphingosine glucohydrolase activity","type":"narrow"},{"name":"inhibition of GlcCer-beta-glucosidase activity","type":"narrow"},{"name":"inhibition of acid beta-glucosidase activity","type":"narrow"},{"name":"inhibition of beta-D-glucocerebrosidase activity","type":"narrow"},{"name":"inhibition of beta-glucocerebrosidase activity","type":"narrow"},{"name":"inhibition of beta-glucosylceramidase activity","type":"narrow"},{"name":"inhibition of ceramide glucosidase activity","type":"narrow"},{"name":"inhibition of glucocerebrosidase activity","type":"narrow"},{"name":"inhibition of glucosphingosine glucosylhydrolase activity","type":"narrow"},{"name":"inhibition of glucosylceramidase activity","type":"narrow"},{"name":"inhibition of glucosylcerebrosidase activity","type":"narrow"},{"name":"inhibition of glucosylsphingosine beta-D-glucosidase activity","type":"narrow"},{"name":"inhibition of glucosylsphingosine beta-glucosidase activity","type":"narrow"},{"name":"inhibition of psychosine hydrolase activity","type":"narrow"},{"name":"negative regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity","type":"exact"},{"name":"negative regulation of GCase activity","type":"exact"},{"name":"negative regulation of GlcCer-beta-glucosidase activity","type":"exact"},{"name":"negative regulation of acid beta-glucosidase activity","type":"exact"},{"name":"negative regulation of beta-D-glucocerebrosidase activity","type":"exact"},{"name":"negative regulation of beta-glucocerebrosidase activity","type":"exact"},{"name":"negative regulation of beta-glucosylceramidase activity","type":"exact"},{"name":"negative regulation of ceramide glucosidase activity","type":"exact"},{"name":"negative regulation of glucocerebrosidase activity","type":"exact"},{"name":"negative regulation of glucosphingosine glucosylhydrolase activity","type":"exact"},{"name":"negative regulation of glucosylcerebrosidase activity","type":"exact"},{"name":"negative regulation of glucosylsphingosine beta-D-glucosidase activity","type":"exact"},{"name":"negative regulation of glucosylsphingosine beta-glucosidase activity","type":"exact"},{"name":"negative regulation of psychosine hydrolase activity","type":"exact"}],"termid":"GO:1905124"}


id: PR:Q9P7F4
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC2E1P3.01 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9P7F4"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc-type alcohol dehydrogenase-like protein C2E1P3.01 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC2E1P3.01","synonyms":[{"name":"Spom972h-SPAC2E1P3.01","type":"exact"}],"termid":"PR:Q9P7F4"}


id: GO:0102184
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: cycloartenol + NADH + O2 + H+ = 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NAD + H2O.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete cycloartenol 4alpha-methyl oxidase activity (obsolete GO:0102184)","termid":"GO:0102184"}


id: MONDO:0001216
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Deterioration of the normal pulp tissue.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dental pulp disorder","termid":"MONDO:0003394"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pulp degeneration","secondary_identifiers":["ICD9:522.2","MEDGEN:19578","icd11.foundation:868011012","SCTID:22361007","UMLS:C0034100","DOID:11189","ICD10CM:K04.2"],"termid":"MONDO:0001216","xrefs":{"Monarch":{"xref_id":"0001216"}}}


id: GO:0048565
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tube development","termid":"GO:0035295"},{"relation_name":"part_of","term_name":"digestive system development","termid":"GO:0055123"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"digestive tract development","synonyms":[{"name":"gut development","type":"broad"},{"name":"intestinal development","type":"narrow"},{"name":"intestine development","type":"narrow"}],"termid":"GO:0048565"}


id: MONDO:0030260
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"pontocerebellar hypoplasia","termid":"MONDO:0020135"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0020022"}],"interesting_parent_ids":["MONDO:0020022"],"is_obsolete":false,"name":"pontocerebellar hypoplasia, type 1E","secondary_identifiers":["GARD:16441","MEDGEN:1788285","OMIM:619303","UMLS:C5543328","DOID:0112330"],"synonyms":[{"name":"PCH1E","type":"exact"},{"name":"pontocerebellar hypoplasia, type 1E","type":"exact"}],"termid":"MONDO:0030260","xrefs":{"Monarch":{"xref_id":"0030260"}}}


id: GO:0098032
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A fiber attached to the collar structure of some icosahedral viral capsids.","definition_xrefs":["GOC:bm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"viral capsid, fiber","termid":"GO:0098022"},{"relation_name":"part_of","term_name":"icosahedral viral capsid, collar","termid":"GO:0098031"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"icosahedral viral capsid, collar fiber","termid":"GO:0098032"}


id: PBO:0113801
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UDP-N-acetylglucosamine transferase anchoring subunit Alg14","termid":"PBO:0113801"}


id: MOD:00332
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-arginine residue to N4-glucosyl-arginine.","definition_xrefs":["PubMed:9536051","RESID:AA0327","PubMed:15279557","PubMed:8521968","Unimod:41#R"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glucosylated residue","termid":"MOD:00433"},{"relation_name":"is_a","term_name":"monohexosylated (Hex1)","termid":"MOD:00761"},{"relation_name":"is_a","term_name":"omega-N-glycosyl-L-arginine","termid":"MOD:01980"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00764"}],"interesting_parent_ids":["MOD:00764"],"is_obsolete":false,"name":"omega-N-glucosyl-L-arginine","synonyms":[{"name":"(2S)-2-amino-5-(beta-D-glucopyranosyl[imino(methylamino)methyl]amino)pentanoic acid","type":"exact"},{"name":"CARBOHYD N-linked (Glc) arginine","type":"exact"},{"name":"Hex","type":"related"},{"name":"Hexose","type":"related"},{"name":"NG-beta-D-glucosylarginine","type":"exact"},{"name":"omega-N-(beta-D-glucosyl)-L-arginine","type":"exact"},{"name":"omega-N-glucosyl-L-arginine","type":"exact"},{"name":"omega-N-glycosyl-L-arginine","type":"exact"}],"termid":"MOD:00332"}


id: PBO:0041102
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"basigin (Ok blood group)","termid":"PBO:0041102"}


id: FYPO:0000850
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to a stress. Typically, a cell population is deemed resistant to a stress if cells in the population grow and divide when exposed to the stress at an intensity at which wild-type cells stop growing (and may die).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vegetative cell population growth phenotype","termid":"FYPO:0001358"},{"relation_name":"is_a","term_name":"resistance to stress","termid":"FYPO:0002046"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000003","FYPO:0000139","FYPO:0005447","FYPO:0001985"],"is_obsolete":false,"name":"resistance to stress during vegetative growth","synonyms":[{"name":"increased vegetative cell population growth during cellular response to stress","type":"exact"},{"name":"resistance to stress during mitotic cell cycle","type":"related"},{"name":"resistant to stress during vegetative growth","type":"exact"}],"termid":"FYPO:0000850"}


id: MONDO:0017381
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Congenital herpes virus infection is a group of anomalies that an infant may present as a result of maternal infection and subsequent fetal infection with herpes virus. This virus causes recurrent cutaneous infections in adults, often involving the lips or the genitalia. Herpes infections in other organs, such as the liver or central nervous system, are less frequent.","definition_xrefs":["Orphanet:293"],"direct_ancestors":[{"relation_name":"is_a","term_name":"herpes simplex infectious disease","termid":"MONDO:0004609"},{"relation_name":"is_a","term_name":"congenital herpes virus infection","termid":"MONDO:0042971"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"congenital herpes simplex virus infection","secondary_identifiers":["MONDO:0022267","SCTID:91576008","UMLS:C0276225","GARD:18687","MEDGEN:82910","ICD9:771.2","NANDO:2200889"],"synonyms":[{"name":"Simplexvirus caused infectious embryofetopathy","type":"exact"},{"name":"Simplexvirus infectious embryofetopathy","type":"exact"},{"name":"antenatal herpes simplex virus infection","type":"exact"},{"name":"congenital herpes simplex","type":"exact"},{"name":"congenital herpes simplex infection","type":"related"},{"name":"mother-to-child transmission of herpes simplex virus infection","type":"exact"},{"name":"neonatal HSV infection","type":"related"},{"name":"neonatal herpes simplex","type":"related"},{"name":"neonatal herpes simplex virus infection","type":"related"}],"termid":"MONDO:0017381","xrefs":{"Monarch":{"xref_id":"0017381"}}}


id: GO:1905285
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The developmental process by which a fibrous ring of heart is generated and organized.","definition_xrefs":["GOC:BHF","PMID:16037571","GOC:rl","GOC:TermGenie","GO_REF:0000083"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tissue morphogenesis","termid":"GO:0048729"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"fibrous ring of heart morphogenesis","synonyms":[{"name":"Lower's ring morphogenesis","type":"related"},{"name":"annulus fibrosus cordis morphogenesis","type":"related"},{"name":"anulus fibrosus cordis morphogenesis","type":"related"},{"name":"anulus fibrosus of heart morphogenesis","type":"exact"},{"name":"aortic annulus morphogenesis","type":"related"},{"name":"atrioventricular ring morphogenesis","type":"related"},{"name":"coronary tendon morphogenesis","type":"related"}],"termid":"GO:1905285"}


id: PBO:0064249
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"plectin","termid":"PBO:0064249"}


id: SO:0000906
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"Attribute to describe a feature that is independently known - not predicted.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"status","termid":"SO:0000905"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"independently_known","synonyms":[{"name":"independently known","type":"exact"}],"termid":"SO:0000906"}


id: PBO:0091328
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Vacuolar Protein Sorting","termid":"PBO:0091328"}


id: GO:0030685
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. Any complex of pre-rRNAs, ribosomal proteins, and associated proteins formed in the nucleolus during ribosome biogenesis.","definition_xrefs":["PMID:10567516"],"gene_count":0,"genotype_count":0,"name":"obsolete nucleolar preribosome (obsolete GO:0030685)","termid":"GO:0030685"}


id: GO:0033291
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex composed of the large and small ribosomal subunits, methionyl-initiatior tRNA, and the capped mRNA. The initiator tRNA is positioned at the ribosomal P site at the AUG codon corresponding to the beginning of the coding region.","definition_xrefs":["GOC:hjd","PMID:15145049"],"direct_ancestors":[{"relation_name":"is_a","term_name":"translation initiation complex","termid":"GO:0070992"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0032991","GO:0005737","GO:0005575"],"is_obsolete":false,"name":"eukaryotic 80S initiation complex","termid":"GO:0033291"}


id: MONDO:0009309
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any chronic granulomatous disease in which the cause of the disease is a mutation in the NCF1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chronic granulomatous disease","termid":"MONDO:0018305"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005570"],"is_obsolete":false,"name":"granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type 1","secondary_identifiers":["MESH:C565532","MEDGEN:341102","DOID:0070192","NANDO:2201281","UMLS:C1856251","OMIM:233700","GARD:15176"],"synonyms":[{"name":"CDG1","type":"related"},{"name":"CGD, autosomal recessive cytochrome B-positive, type 1","type":"related"},{"name":"NCF1 chronic granulomatous disease","type":"exact"},{"name":"Ncf1, deficiency of","type":"related"},{"name":"Soc2, deficiency of","type":"related"},{"name":"chronic granulomatous disease 1, autosomal recessive","type":"exact"},{"name":"chronic granulomatous disease caused by mutation in NCF1","type":"exact"},{"name":"granulomatous disease, chronic, autosomal recessive, cytochrome b-POSITIVE, type I","type":"related"},{"name":"granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type 1","type":"exact"},{"name":"granulomatous disease, chronic, due to Ncf1 deficiency","type":"related"},{"name":"neutrophil cytosol Factor 1, deficiency of","type":"related"},{"name":"p47-PHOX, deficiency of","type":"related"},{"name":"soluble oxidase component II, deficiency of","type":"related"}],"termid":"MONDO:0009309","xrefs":{"Monarch":{"xref_id":"0009309"}}}


id: GO:0016863
data:
  {"annotated_genes":["SJAG_04307","SJAG_03598"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[94415],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000247"},{"annotations":[76415],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004452"}]},"cv_name":"molecular_function","definition":"Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, one or more carbon-carbon double bonds in the molecule are rearranged, and no oxidized product appears.","definition_xrefs":["EC:5.3.3.-","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intramolecular oxidoreductase activity","termid":"GO:0016860"}],"gene_count":2,"genes_by_uniquename":{"SJAG_03598":null,"SJAG_04307":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016853"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016853"],"is_obsolete":false,"name":"intramolecular oxidoreductase activity, transposing C=C bonds","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"intramolecular isomerase activity, transposing C=C bonds","type":"exact"}],"termid":"GO:0016863","terms_by_termid":{"GO:0000247":null,"GO:0004452":null}}


id: GO:0050398
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: a wax ester + H2O = a long-chain alcohol + a long-chain carboxylate.","definition_xrefs":["EC:3.1.1.50","MetaCyc:WAX-ESTER-HYDROLASE-RXN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxylic ester hydrolase activity","termid":"GO:0052689"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"}],"interesting_parent_ids":["GO:0003824","GO:0016788","GO:0003674","GO:0016787"],"is_obsolete":false,"name":"wax-ester hydrolase activity","secondary_identifiers":["RHEA:13577"],"synonyms":[{"name":"WEH","type":"related"},{"name":"jojoba wax esterase","type":"narrow"},{"name":"wax-ester acylhydrolase activity","type":"related"}],"termid":"GO:0050398"}


id: PBO:0060827
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NECTIN2 pseudogene 1","termid":"PBO:0060827"}


id: PBO:0086427
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative hexose transporter that is nearly identical to Hxt11p; has similarity to major facilitator superfamily (MFS) transporters, expression of HXT9 is regulated by transcription factors Pdr1p and Pdr3p","termid":"PBO:0086427"}


id: SO:0000871
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"An mRNA that is polyadenylated.","definition_xrefs":["SO:xp"],"direct_ancestors":[{"relation_name":"adjacent_to","term_name":"polyA_sequence","termid":"SO:0000610"},{"relation_name":"has_quality","term_name":"polyadenylated","termid":"SO:0000246"},{"relation_name":"is_a","term_name":"mRNA","termid":"SO:0000234"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"polyadenylated_mRNA","synonyms":[{"name":"polyadenylated mRNA","type":"exact"}],"termid":"SO:0000871"}


id: GO:0050325
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: H2O + NAD+ + tauropine = H+ + NADH + pyruvate + taurine.","definition_xrefs":["RHEA:12580","EC:1.5.1.23"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor","termid":"GO:0016646"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"tauropine dehydrogenase activity","secondary_identifiers":["KEGG_REACTION:R01683","MetaCyc:TAUROPINE-DEHYDROGENASE-RXN"],"synonyms":[{"name":"2-N-(D-1-carboxyethyl)taurine:NAD+ oxidoreductase (taurine-forming)","type":"related"},{"name":"N2-(D-1-carboxyethyl)taurine:NAD+ oxidoreductase (taurine-forming)","type":"related"}],"termid":"GO:0050325"}


id: GO:2000170
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of peptidyl-cysteine S-nitrosylation.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of protein modification process","termid":"GO:0031401"},{"relation_name":"is_a","term_name":"regulation of peptidyl-cysteine S-nitrosylation","termid":"GO:2000169"},{"relation_name":"positively_regulates","term_name":"peptidyl-cysteine S-nitrosylation","termid":"GO:0018119"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of peptidyl-cysteine S-nitrosylation","termid":"GO:2000170"}


id: MONDO:0019852
data:
  {"annotated_genes":["SJAG_03051","SJAG_02643","SJAG_04148","SJAG_04114","SJAG_02339","SJAG_04738","SJAG_00377","SJAG_02954","SJAG_03418","SJAG_03698","SJAG_03720","SJAG_02690","SJAG_04703","SJAG_04950","SJAG_02294","SJAG_00103"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87188],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008840"},{"annotations":[87746],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009258"},{"annotations":[88756],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0030736"},{"annotations":[87420],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013689"},{"annotations":[88185],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0054850"},{"annotations":[89015],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013972"},{"annotations":[87790],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014126"},{"annotations":[86827],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0976232"},{"annotations":[87406],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014843"},{"annotations":[88202,88203],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0054862"},{"annotations":[87491],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0030870"},{"annotations":[87899],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0958035"},{"annotations":[88818],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010350"},{"annotations":[88390,88391],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014321"}]},"cv_name":"mondo","definition":"An instance of primary ovarian failure that is caused by an inherited modification of the individual's genome.","definition_xrefs":["MONDO:patterns/hereditary"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"primary ovarian failure","termid":"MONDO:0005387"},{"relation_name":"is_a","term_name":"hereditary endocrine growth disease","termid":"MONDO:0015514"},{"relation_name":"is_a","term_name":"female infertility","termid":"MONDO:0021124"}],"gene_count":16,"genes_by_uniquename":{"SJAG_00103":null,"SJAG_00377":null,"SJAG_02294":null,"SJAG_02339":null,"SJAG_02643":null,"SJAG_02690":null,"SJAG_02954":null,"SJAG_03051":null,"SJAG_03418":null,"SJAG_03698":null,"SJAG_03720":null,"SJAG_04114":null,"SJAG_04148":null,"SJAG_04703":null,"SJAG_04738":null,"SJAG_04950":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005047"}],"interesting_parent_ids":["MONDO:0005047"],"is_obsolete":false,"name":"inherited primary ovarian failure","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C2930861","GARD:19294","MEDGEN:443920","ICD10CM:E28.3","Orphanet:95710","OMIMPS:311360"],"synonyms":[{"name":"hereditary primary ovarian failure","type":"exact"},{"name":"inherited POI","type":"exact"},{"name":"inherited premature ovarian failure","type":"exact"},{"name":"inherited primary ovarian insufficiency","type":"exact"},{"name":"non-acquired premature ovarian failure","type":"related"}],"termid":"MONDO:0019852","terms_by_termid":{"MONDO:0008840":null,"MONDO:0009258":null,"MONDO:0010350":null,"MONDO:0013689":null,"MONDO:0013972":null,"MONDO:0014126":null,"MONDO:0014321":null,"MONDO:0014843":null,"MONDO:0030736":null,"MONDO:0030870":null,"MONDO:0054850":null,"MONDO:0054862":null,"MONDO:0958035":null,"MONDO:0976232":null},"xrefs":{"Monarch":{"xref_id":"0019852"}}}


id: GO:0141204
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of dipeptide from the lysosomal lumen across the lysosomal membrane and into the cytosol.","definition_xrefs":["PMID:38507452"],"direct_ancestors":[{"relation_name":"is_a","term_name":"peptide transport","termid":"GO:0015833"},{"relation_name":"is_a","term_name":"transmembrane transport from lysosomal lumen to cytosol","termid":"GO:0170063"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0055085"}],"interesting_parent_ids":["GO:0008150","GO:0051179","GO:0006810","GO:0055085"],"is_obsolete":false,"name":"dipeptide transmembrane transport from lysosomal lumen to cytosol","synonyms":[{"name":"dipeptide export from lysosomal lumen","type":"exact"},{"name":"dipeptide export from lysosome","type":"exact"},{"name":"transmembrane dipeptide transport from lysosomal lumen to cytosol","type":"exact"}],"termid":"GO:0141204"}


id: FYPO:0006347
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to mechlorethamine. Cells stop growing (and may die) at a concentration of mechlorethamine that allows wild type cells to grow.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased sensitivity to chemical during vegetative growth","termid":"FYPO:0000127"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0002683"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0000003","FYPO:0002683","FYPO:0000139","FYPO:0001985","FYPO:0005447"],"is_obsolete":false,"name":"sensitive to mechlorethamine","synonyms":[{"name":"hypersensitive to mechlorethamine","type":"exact"},{"name":"sensitive to 2-chloro-N-(2-chloroethyl)-N-methylethanamine","type":"exact"},{"name":"sensitive to HN2","type":"exact"},{"name":"sensitive to bis(2-chloroethyl)methylamine","type":"exact"},{"name":"sensitive to mechlorethamine during mitotic cell cycle","type":"related"},{"name":"sensitive to mechlorethamine during vegetative growth","type":"exact"}],"termid":"FYPO:0006347"}


id: PBO:0045201
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DnaJ heat shock protein family (Hsp40) member B12","termid":"PBO:0045201"}


id: PBO:0069087
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 334, pseudogene","termid":"PBO:0069087"}


id: PBO:0114750
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitotic and meiotic cohesin unloading complex subunit Pds5","termid":"PBO:0114750"}


id: GO:0014871
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which actin and myosin interact, split ATP and generate force during skeletal muscle contraction. This process is one of the components of the regulation of the force of skeletal muscle contraction.","definition_xrefs":["GOC:mtg_muscle"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of muscle filament sliding involved in regulation of the velocity of shortening in skeletal muscle contraction","termid":"GO:0014880"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006810","GO:0008150"],"is_obsolete":false,"name":"cross bridge formation involved in regulation of the velocity of shortening in skeletal muscle contraction","termid":"GO:0014871"}


id: PBO:0113805
data:
  {"annotation_feature_type":"gene","cv_name":"misc","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peak copy number 100 at endocytic sites","termid":"PBO:0113805"}


id: PBO:0005720
data:
  {"annotation_feature_type":"gene","cv_name":"disease_associated","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"renal cell cancer","termid":"PBO:0005720"}


id: GO:0000923
data:
  {"annotated_genes":["SJAG_02609","SJAG_03264","SJAG_02761","SJAG_02737","SJAG_01756","SJAG_00856","SJAG_02886","SJAG_03073","SJAG_03052","SJAG_01215","SJAG_07018","SJAG_03835"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[101900,102184,102799,103244,104138,108274,110681,111441,112423,114618,118797,119050],"is_not":false,"summary":null,"term":"GO:0000923"}]},"cv_name":"cellular_component","definition":"A microtubule organizing center formed by a band of gamma-tubulin that is recruited to a circumferential band of F-actin at the midpoint of a cell and which nucleates microtubules from the cell division site at the end of mitosis.","definition_xrefs":["PMID:11792817"],"direct_ancestors":[{"relation_name":"is_a","term_name":"microtubule organizing center","termid":"GO:0005815"},{"relation_name":"part_of","term_name":"cell division site","termid":"GO:0032153"}],"gene_count":12,"genes_by_uniquename":{"SJAG_00856":null,"SJAG_01215":null,"SJAG_01756":null,"SJAG_02609":null,"SJAG_02737":null,"SJAG_02761":null,"SJAG_02886":null,"SJAG_03052":null,"SJAG_03073":null,"SJAG_03264":null,"SJAG_03835":null,"SJAG_07018":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0015630"}],"interesting_parent_ids":["GO:0015630","GO:0005575"],"is_obsolete":false,"name":"equatorial microtubule organizing center","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"EMTOC","type":"exact"},{"name":"equatorial microtubule organising centre","type":"exact"}],"termid":"GO:0000923","terms_by_termid":{"GO:0000923":null}}


id: PBO:0079537
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UDP-N-acetylglucosamine pyrophosphorylase 1","termid":"PBO:0079537"}


id: MONDO:1011796
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"musculoskeletal system disorder, non-human animal","termid":"MONDO:1011335"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"high-frequency tremor, non-human animal","secondary_identifiers":["OMIA:001200"],"termid":"MONDO:1011796","xrefs":{"Monarch":{"xref_id":"1011796"}}}


id: PBO:0039838
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rho GTPase activating protein 8","termid":"PBO:0039838"}


id: PBO:0049526
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"H2AZ1 divergent transcript","termid":"PBO:0049526"}


id: MONDO:0006201
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An adenoid cystic carcinoma that affects the ethmoid sinus.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ethmoid sinus cancer","termid":"MONDO:0001763"},{"relation_name":"is_a","term_name":"paranasal sinus adenoid cystic carcinoma","termid":"MONDO:0006352"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"ethmoid sinus adenoid cystic carcinoma","secondary_identifiers":["NCIT:C6238","DOID:2764","EFO:1000246","MEDGEN:232471","UMLS:C1333473"],"synonyms":[{"name":"adenoid cystic carcinoma of ethmoid sinus","type":"related"},{"name":"adenoid cystic carcinoma of the ethmoid sinus","type":"exact"}],"termid":"MONDO:0006201","xrefs":{"Monarch":{"xref_id":"0006201"}}}


id: GO:0015561
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: rhamnose(out) + H+(out) = rhamnose(in) + H+(in).","definition_xrefs":["TC:2.A.7.6"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hexose:proton symporter activity","termid":"GO:0009679"},{"relation_name":"is_a","term_name":"rhamnose transmembrane transporter activity","termid":"GO:0015153"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0003674","GO:0005215","GO:0022857"],"is_obsolete":false,"name":"rhamnose:proton symporter activity","synonyms":[{"name":"rhamnose:hydrogen symporter activity","type":"exact"}],"termid":"GO:0015561"}


id: PBO:0044840
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"defensin beta 128","termid":"PBO:0044840"}


id: PBO:0066502
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ring finger and WD repeat domain 3","termid":"PBO:0066502"}


id: PBO:0029397
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-delayed_onset_of_protein_localization_to_nucleoplasm","termid":"PBO:0029397"}


id: GO:0010721
data:
  {"annotated_genes":["SJAG_04140","SJAG_02169"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[113051],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0075297"},{"annotations":[92537],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051517"}]},"cv_name":"biological_process","definition":"Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.","definition_xrefs":["GOC:tb","GOC:dph","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cell differentiation","termid":"GO:0045596"},{"relation_name":"is_a","term_name":"regulation of cell development","termid":"GO:0060284"},{"relation_name":"negatively_regulates","term_name":"cell development","termid":"GO:0048468"}],"gene_count":2,"genes_by_uniquename":{"SJAG_02169":null,"SJAG_04140":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of cell development","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0010721","terms_by_termid":{"GO:0051517":null,"GO:0075297":null}}


id: FYPO:0007139
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortical nodes is abolished during interphase of the mitotic cell cycle.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished protein localization to medial cortical node","termid":"FYPO:0003919"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000138"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001320","FYPO:0001985","FYPO:0000138","FYPO:0000002"],"is_obsolete":false,"name":"abolished protein localization to medial cortical node during mitotic interphase","synonyms":[{"name":"abolished protein localisation to medial cortical node during mitotic interphase","type":"exact"},{"name":"abolished protein localization to cortical medial dot during mitotic interphase","type":"exact"},{"name":"abolished protein localization to cytokinetic nodes during mitotic interphase","type":"related"},{"name":"abolished protein localization to medial cortical node during interphase during vegetative growth","type":"exact"},{"name":"abolished protein localization to medial cortical node during interphase of mitotic cell cycle","type":"exact"},{"name":"abolished protein localization to medial cortical nodes during mitotic interphase","type":"exact"},{"name":"abolished protein recruitment to medial cortical node during mitotic interphase","type":"related"},{"name":"protein localization to medial cortical node abolished during mitotic interphase","type":"exact"}],"termid":"FYPO:0007139"}


id: PBO:0044498
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CYFIP related Rac1 interactor B","termid":"PBO:0044498"}


id: GO:0110011
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane.","definition_xrefs":["PMID:27404358","GOC:ha"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of extracellular matrix organization","termid":"GO:1903053"},{"relation_name":"regulates","term_name":"basement membrane organization","termid":"GO:0071711"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of basement membrane organization","termid":"GO:0110011"}


id: PBO:0038975
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ADP dependent glucokinase","termid":"PBO:0038975"}


id: GO:0047242
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: a hydroxyanthraquinone + UDP-D-glucose = a glucosyloxyanthraquinone + UDP.","definition_xrefs":["EC:2.4.1.181"],"direct_ancestors":[{"relation_name":"is_a","term_name":"UDP-glucosyltransferase activity","termid":"GO:0035251"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016757"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016740","GO:0016757","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"hydroxyanthraquinone glucosyltransferase activity","secondary_identifiers":["MetaCyc:2.4.1.181-RXN"],"synonyms":[{"name":"UDP-glucose:hydroxyanthraquinone O-glucosyltransferase activity","type":"related"},{"name":"UDPglucose:hydroxyanthraquinone O-glucosyltransferase activity","type":"related"},{"name":"anthraquinone-specific glucosyltransferase activity","type":"related"},{"name":"uridine diphosphoglucose-anthraquinone glucosyltransferase activity","type":"related"}],"termid":"GO:0047242"}


id: GO:0002874
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of chronic inflammatory response","termid":"GO:0002676"},{"relation_name":"is_a","term_name":"regulation of inflammatory response to antigenic stimulus","termid":"GO:0002861"},{"relation_name":"regulates","term_name":"chronic inflammatory response to antigenic stimulus","termid":"GO:0002439"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of chronic inflammatory response to antigenic stimulus","termid":"GO:0002874"}


id: PBO:0000673
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2.4.2.29","termid":"PBO:0000673"}


id: PBO:0051269
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin kappa deleting element or like","termid":"PBO:0051269"}


id: GO:2000437
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of monocyte extravasation.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cellular extravasation","termid":"GO:0002691"},{"relation_name":"is_a","term_name":"regulation of mononuclear cell migration","termid":"GO:0071675"},{"relation_name":"regulates","term_name":"monocyte extravasation","termid":"GO:0035696"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of monocyte extravasation","termid":"GO:2000437"}


id: GO:0019325
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways resulting in the breakdown of fructose that occurs in the absence of oxygen.","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete anaerobic fructose catabolic process (obsolete GO:0019325)","synonyms":[{"name":"anaerobic fructose breakdown","type":"exact"},{"name":"anaerobic fructose catabolism","type":"exact"},{"name":"anaerobic fructose degradation","type":"exact"}],"termid":"GO:0019325"}


id: MOD:00877
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"dimethyl pimelimidate modification from Unimod","definition_xrefs":["URL:http://www.piercenet.com/files/0668ss5.pdf","Unimod:455"],"direct_ancestors":[{"relation_name":"is_a","term_name":"reagent derivatized residue","termid":"MOD:00848"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"imidoester crosslink dimethyl pimelimidate singly attached","synonyms":[{"name":"One end of crosslink attached, one end free","type":"related"},{"name":"Xlink:DMP-s","type":"related"}],"termid":"MOD:00877"}


id: GO:0051422
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops or reduces the rate of endo-(1->4)-beta-xylanase activity, the catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.","definition_xrefs":["EC:3.2.1.8","GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of endo-1,4-beta-xylanase activity (obsolete GO:0051422)","synonyms":[{"name":"down regulation of endo-1,4-beta-xylanase activity","type":"exact"},{"name":"down-regulation of endo-1,4-beta-xylanase activity","type":"exact"},{"name":"downregulation of endo-1,4-beta-xylanase activity","type":"exact"},{"name":"endo-1,4-beta-xylanase inhibitor","type":"related"},{"name":"inhibition of endo-1,4-beta-xylanase activity","type":"narrow"},{"name":"xylanase inhibitor","type":"related"}],"termid":"GO:0051422"}


id: PBO:0018249
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PI31 proteasome inhibitor Fub1 (predicted)","termid":"PBO:0018249"}


id: MONDO:0002692
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Formation or presence of a blood clot (thrombus) in the cranial sinuses, large endothelium-lined venous channels situated within the skull. Intracranial sinuses, also called cranial venous sinuses, include the superior sagittal, cavernous, lateral, petrous sinuses, and many others. Cranial sinus thrombosis can lead to severe headache; seizure; and other neurological defects.","definition_xrefs":["MESH:D012851"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracranial thrombosis","termid":"MONDO:0002907"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"intracranial sinus thrombosis","secondary_identifiers":["DOID:3572","UMLS:C0037198","MEDGEN:20771"],"termid":"MONDO:0002692","xrefs":{"Monarch":{"xref_id":"0002692"}}}


id: PBO:0051859
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"iron-sulfur cluster assembly 1 pseudogene 5","termid":"PBO:0051859"}


id: PBO:0065966
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RAD51AP1 pseudogene 1","termid":"PBO:0065966"}


id: PBO:0034338
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-in_1_to_1_orthology_relationship_with","termid":"PBO:0034338"}


id: PBO:0082122
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Acetyltransferase required for biogenesis of small ribosomal subunit; responsible for incorporation of N4-acetylcytidine into mRNAs; heterozygous mutant shows haploinsufficiency in K1 killer toxin resistance; essential gene; NAT10, the human homolog, implicated in several types of cancer and premature aging","termid":"PBO:0082122"}


id: GO:0033462
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"A triplet codon-amino acid adaptor activity that recognizes a GGC codon.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"triplet codon-amino acid adaptor activity","termid":"GO:0030533"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0060090"},{"rel_name":"is_a","termid":"GO:0003723"}],"interesting_parent_ids":["GO:0005488","GO:0003674","GO:0060090","GO:0003723"],"is_obsolete":false,"name":"GGC codon-amino acid adaptor activity","synonyms":[{"name":"glycine tRNA","type":"related"}],"termid":"GO:0033462"}


id: PBO:0109119
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SET domain containing 3, actin N3(tau)-histidine methyltransferase","termid":"PBO:0109119"}


id: MONDO:0016057
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Brain tissue herniation through a congenital or acquired defect in the skull. The majority of congenital encephaloceles occur in the occipital or frontal regions. Clinical features include a protuberant mass that may be pulsatile. The quantity and location of protruding neural tissue determines the type and degree of neurologic deficit. Visual defects, psychomotor developmental delay, and persistent motor deficits frequently occur.","definition_xrefs":["MESH:D004677"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cephalocele","termid":"MONDO:0017078"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320"],"is_obsolete":false,"name":"isolated encephalocele","secondary_identifiers":["NORD:1089","MedDRA:10014617","Orphanet:199647","UMLS:C5680519","GARD:6333","MEDGEN:1830107"],"synonyms":[{"name":"Encephalocele","type":"exact"},{"name":"bifid cranium","type":"related"},{"name":"craniocele","type":"related"},{"name":"cranium bifidum","type":"related"},{"name":"encephalocele","type":"related"}],"termid":"MONDO:0016057","xrefs":{"Monarch":{"xref_id":"0016057"}}}


id: MONDO:0017812
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare PIK3CA-related overgrowth syndrome disease characterized by segmental and progressive overgrowth, predominantly involving the adipose tissue, or a mixture of adipose and fibrous tissue, with variable involvement of subcutaneous and muscular tissue, as well as skeletal overgrowth. Overgrowth severity and range is highly variable, although frequently it is asymmetric and disproportionate, it affects lower extremities more than the upper ones, and progresses in a distal to proximal patten. Congenital overgrowth is typically associated.","definition_xrefs":["Orphanet:314662"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"overgrowth syndrome","termid":"MONDO:0019716"},{"relation_name":"is_a","term_name":"PIK3CA-related overgrowth spectrum","termid":"MONDO:1040002"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"segmental progressive overgrowth syndrome with fibroadipose hyperplasia","secondary_identifiers":["GARD:21384","MEDGEN:1673986","UMLS:C5192432"],"termid":"MONDO:0017812","xrefs":{"Monarch":{"xref_id":"0017812"}}}


id: PBO:0050194
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"high mobility group nucleosome binding domain 1 pseudogene 11","termid":"PBO:0050194"}


id: PBO:0072865
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SAM and SH3 domain containing 3","termid":"PBO:0072865"}


id: GO:0070390
data:
  {"annotated_genes":["SJAG_00641","SJAG_04347","SJAG_04656","SJAG_00298","SJAG_04472"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[71630,74445,76106,78421,113601],"is_not":false,"summary":null,"term":"GO:0070390"}]},"cv_name":"cellular_component","definition":"A protein complex that couples SAGA-dependent gene expression to mRNA export at the inner side of the nuclear pore complex (NPC). The TREX-2 complex is tethered to the inner side of the NPC via the nucleoporins Nup1 and Nup60; in S. cerevisiae it contains Sac3p, Thp1p, Sem1, Sus1p and Cdc31p.","definition_xrefs":["GOC:dgf","GOC:mah","PMID:19289793","PMID:28334829","PMID:17786152"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nuclear protein-containing complex","termid":"GO:0140513"}],"gene_count":5,"genes_by_uniquename":{"SJAG_00298":null,"SJAG_00641":null,"SJAG_04347":null,"SJAG_04472":null,"SJAG_04656":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005634"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005634","GO:0032991","GO:0005575"],"is_obsolete":false,"name":"transcription export complex 2","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"Sac3-Thp1-Sus1-Sem1-Cdc31 complex","type":"exact"},{"name":"TREX-2 complex","type":"exact"}],"termid":"GO:0070390","terms_by_termid":{"GO:0070390":null}}


id: PBO:0000427
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA Z4","termid":"PBO:0000427"}


id: GO:0018781
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 1-halo or 1-pseudohalo-S-triazine = 1-hydroxy-S-triazine.","definition_xrefs":["UM-BBD_ruleID:bt0330"],"gene_count":0,"genotype_count":0,"name":"obsolete S-triazine hydrolase activity (obsolete GO:0018781)","termid":"GO:0018781"}


id: PBO:0084173
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"High osmolarity-regulated gene of unknown function","termid":"PBO:0084173"}


id: MONDO:0010434
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Synovial sarcoma is an aggressive soft tissue sarcoma, occurring most commonly in adolescents and young adults (15 to 40 years), usually localized near the large joints of the extremities but also in the head and neck, mediastinum and viscera (lung, kidney etc), clinically presenting as a deep seated swelling or a painful mass often with an initial indolent course and is characterized by its local invasiveness and a propensity to metastasize. The origin of synovial sarcoma is likely from multipotent mesenchymal cells and not synovium (contrary to its name).","definition_xrefs":["Orphanet:3273"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"synovium cancer","termid":"MONDO:0002403"},{"relation_name":"is_a","term_name":"soft tissue sarcoma","termid":"MONDO:0018078"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"synovial sarcoma","secondary_identifiers":["UMLS:C0039101","ONCOTREE:SYNS","GARD:7721","EFO:0001376","MESH:D013584","SCTID:302851001","HP:0012570","ICD9:171.9","ICDO:9040/3","MedDRA:10042863","MEDGEN:21050","NCIT:C3400","NANDO:2200061","OMIM:300813","DOID:5485"],"synonyms":[{"name":"SS","type":"broad"},{"name":"Synovialosarcoma","type":"exact"},{"name":"sarcoma, synovial","type":"related"},{"name":"sarcoma, synovial, malignant","type":"exact"},{"name":"synovial sarcoma","type":"exact"},{"name":"synovial sarcoma (disease)","type":"exact"}],"termid":"MONDO:0010434","xrefs":{"Monarch":{"xref_id":"0010434"}}}


id: PBO:0044976
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DEAH-box helicase 16","termid":"PBO:0044976"}


id: PBO:0049801
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hypocretin neuropeptide precursor","termid":"PBO:0049801"}


id: PR:Q92366
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A 60S ribosomal protein L29 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","PANTHER:PTHR12884:SF0"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"60S ribosomal protein L29 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC776.01","secondary_identifiers":["UniProtKB:Q92366"],"synonyms":[{"name":"L43 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"SPBC776.01","type":"related"},{"name":"Spom972h-RPL29","type":"exact"}],"termid":"PR:Q92366"}


id: PBO:0027052
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-long_astral_microtubules_during_mitotic_anaphase_A","termid":"PBO:0027052"}


id: MONDO:0800375
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"DEND syndrome","termid":"MONDO:0019207"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005015"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0037792"},{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0019254"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0005015","MONDO:0037792","MONDO:0004335","MONDO:0019254"],"is_obsolete":false,"name":"developmental delay, epilepsy, and neonatal diabetes 1","secondary_identifiers":["MEDGEN:1709191","UMLS:C5394597"],"synonyms":[{"name":"DEND1","type":"exact"}],"termid":"MONDO:0800375","xrefs":{"Monarch":{"xref_id":"0800375"}}}


id: PBO:0001850
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome c1 heme lyase (predicted)","termid":"PBO:0001850"}


id: PR:Q9P6P2
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- rrp36 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9P6P2"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"rRNA biogenesis protein rrp36 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC823.04","synonyms":[{"name":"Spom972h-rrp36","type":"exact"},{"name":"ribosomal RNA-processing protein 36 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9P6P2"}


id: PBO:0066616
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RHPN1 antisense RNA 1 (head to head)","termid":"PBO:0066616"}


id: GO:0070069
data:
  {"annotated_genes":["SJAG_00755","SJAG_00601","SJAG_MIT03","SJAG_01763","SJAG_02646","SJAG_07007","SJAG_01355","SJAG_MIT20","SJAG_00080","SJAG_05629","SJAG_MIT04","SJAG_MIT13","SJAG_00976","SJAG_01190","SJAG_07006","SJAG_01490","SJAG_03490","SJAG_02504","SJAG_01077"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[119547,73916,77424,120936,77506,105895,115257,62513,75502],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0045275"},{"annotations":[116086,110123,120961,62547,73579,75991,117318,120909,120931,69434],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0045277"}]},"cv_name":"cellular_component","definition":"A protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"catalytic complex","termid":"GO:1902494"}],"gene_count":19,"genes_by_uniquename":{"SJAG_00080":null,"SJAG_00601":null,"SJAG_00755":null,"SJAG_00976":null,"SJAG_01077":null,"SJAG_01190":null,"SJAG_01355":null,"SJAG_01490":null,"SJAG_01763":null,"SJAG_02504":null,"SJAG_02646":null,"SJAG_03490":null,"SJAG_05629":null,"SJAG_07006":null,"SJAG_07007":null,"SJAG_MIT03":null,"SJAG_MIT04":null,"SJAG_MIT13":null,"SJAG_MIT20":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"cytochrome complex","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null,"GO_REF:0000117":null},"termid":"GO:0070069","terms_by_termid":{"GO:0045275":null,"GO:0045277":null}}


id: PBO:0088547
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"rRNA processing protein Efg1","termid":"PBO:0088547"}


id: GO:0070024
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that contains the cell surface signaling molecule CD19, the Ras guanine nucleotide exchange factor Vav, and the regulatory subunit alpha of phosphatidylinositol 3-kinase (PI3K).","definition_xrefs":["PMID:7528218"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plasma membrane protein complex","termid":"GO:0098797"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005886"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0032991","GO:0005886","GO:0005575"],"is_obsolete":false,"name":"CD19-Vav-PIK3R1 complex","synonyms":[{"name":"CD19-Vav-PI 3-kinase (p85 subunit) complex","type":"exact"}],"termid":"GO:0070024"}


id: GO:0006579
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of any betaine, the N-trimethyl derivative of an amino acid.","definition_xrefs":["GOC:mah","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amino-acid betaine metabolic process","termid":"GO:0006577"},{"relation_name":"is_a","term_name":"modified amino acid catabolic process","termid":"GO:0042219"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"amino-acid betaine catabolic process","synonyms":[{"name":"betaine breakdown","type":"exact"},{"name":"betaine catabolic process","type":"exact"},{"name":"betaine catabolism","type":"exact"},{"name":"betaine degradation","type":"exact"}],"termid":"GO:0006579"}


id: FYPO:0007488
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the Golgi apparatus is decreased, and the protein is present in the vacuole instead.","definition_xrefs":["PomBase:mah","PMID:32918581"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased protein localization to Golgi apparatus","termid":"FYPO:0004786"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0000138","FYPO:0005447","FYPO:0001320"],"is_obsolete":false,"name":"decreased protein localization to Golgi apparatus, with protein mislocalized to vacuole","synonyms":[{"name":"decreased protein localisation to Golgi apparatus, with protein mislocalised to vacuole","type":"exact"},{"name":"decreased protein localization to Golgi apparatus, with protein mislocalized to vacuole during mitotic cell cycle","type":"related"},{"name":"decreased protein localization to Golgi apparatus, with protein mislocalized to vacuole during vegetative growth","type":"exact"},{"name":"reduced protein localization to Golgi apparatus, with protein mislocalized to vacuole","type":"exact"}],"termid":"FYPO:0007488"}


id: SO:0001578
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A sequence variant where at least one base of the terminator codon (stop) is changed, resulting in an elongated transcript.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"terminator_codon_variant","termid":"SO:0001590"},{"relation_name":"is_a","term_name":"feature_elongation","termid":"SO:0001907"},{"relation_name":"is_a","term_name":"nonsynonymous_variant","termid":"SO:0001992"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"stop_lost","secondary_identifiers":["http://snpeff.sourceforge.net/SnpEff_manual.html","http://vat.gersteinlab.org/formats.php","http:www.ensembl.org/info/genome/variation/predicted_data.html#consequences","http://snp.gs.washington.edu/SeattleSeqAnnotation137/HelpHowToUse.jsp"],"synonyms":[{"name":"ANNOVAR:stoploss","type":"exact"},{"name":"Jannovar:stop_lost","type":"exact"},{"name":"Seattleseq:stop-lost","type":"exact"},{"name":"Seattleseq:stop-lost-near-splice","type":"related"},{"name":"VAAST:stop_lost","type":"exact"},{"name":"VAT:removedStop","type":"exact"},{"name":"VEP:stop_lost","type":"exact"},{"name":"snpEff:STOP_LOST","type":"exact"},{"name":"stop codon lost","type":"exact"},{"name":"stop lost","type":"exact"}],"termid":"SO:0001578"}


id: GO:0008953
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: penicillin + H2O = a carboxylate + 6-aminopenicillanate.","definition_xrefs":["EC:3.5.1.11"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides","termid":"GO:0016811"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0016810"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016787","GO:0016810"],"is_obsolete":false,"name":"penicillin amidase activity","secondary_identifiers":["RHEA:18693","MetaCyc:PENICILLIN-AMIDASE-RXN"],"synonyms":[{"name":"alpha-acylamino-beta-lactam acylhydrolase activity","type":"related"},{"name":"ampicillin acylase activity","type":"related"},{"name":"benzylpenicillin acylase activity","type":"related"},{"name":"novozym 217","type":"related"},{"name":"palmitoleoyl [acyl-carrier protein]-dependent acyltransferase activity","type":"exact"},{"name":"penicillin acylase activity","type":"related"},{"name":"penicillin amidohydrolase activity","type":"related"},{"name":"semacylase activity","type":"related"}],"termid":"GO:0008953"}


id: PBO:0059172
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myelin protein zero like 3","termid":"PBO:0059172"}


id: MONDO:0004635
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A primary or metastatic malignant neoplasm that affects the postcricoid region.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hypopharynx cancer","termid":"MONDO:0005806"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0004335"],"is_obsolete":false,"name":"postcricoid region cancer","secondary_identifiers":["NCIT:C9323","SCTID:363400004","MEDGEN:141673","ICD9:148.0","UMLS:C0496769","DOID:8660"],"synonyms":[{"name":"malignant neoplasm of postcricoid area","type":"exact"},{"name":"malignant neoplasm of the postcricoid area","type":"exact"},{"name":"malignant postcricoid neoplasm","type":"exact"},{"name":"malignant postcricoid tumor","type":"exact"},{"name":"malignant postcricoid tumour","type":"exact"},{"name":"malignant tumor of pharyngoesophageal junction","type":"exact"},{"name":"malignant tumor of postcricoid area","type":"exact"},{"name":"malignant tumor of the postcricoid area","type":"exact"},{"name":"malignant tumour of pharyngoesophageal junction","type":"exact"},{"name":"malignant tumour of postcricoid area","type":"exact"},{"name":"malignant tumour of the postcricoid area","type":"exact"}],"termid":"MONDO:0004635","xrefs":{"Monarch":{"xref_id":"0004635"}}}


id: GO:0002010
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the molecular signal from the arterial baroreceptors is relayed to the vasomotor center causing it to signal increase arterial pressure.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nervous system process involved in regulation of systemic arterial blood pressure","termid":"GO:0001976"},{"relation_name":"part_of","term_name":"baroreceptor response to decreased systemic arterial blood pressure","termid":"GO:0001982"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"excitation of vasomotor center by baroreceptor signaling","synonyms":[{"name":"excitation of vasomotor center by baroreceptor signalling","type":"exact"}],"termid":"GO:0002010"}


id: GO:0043490
data:
  {"annotated_genes":["SJAG_00714","SJAG_01753","SJAG_00522","SJAG_03306"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[89659,98375,113664,118417],"is_not":false,"summary":null,"term":"GO:0043490"}]},"cv_name":"biological_process","definition":"The process of transferring reducing equivalents from NADH in the cytosol to the mitochondria via malate. Cytosolic aspartate aminotransferase converts aspartate to oxaloacetate, and cytosolic malate dehydrogenase uses NADH to convert oxaloacetate to malate in the cytosol; the malate-alpha-ketoglutarate carrier then transports the malate into the mitochondria where mitochondrial malate dehydrogenase uses NAD to convert malate back to oxaloacetate; the electrons on the reduced NADH are then available for use in the electron transport chain; mitochondrial aspartate aminotransferase converts oxaloacetate to aspartate, and the glutamate-aspartate carrier transports the aspartate back to the cytosol to complete the cycle.","definition_xrefs":["GOC:sjm","PMID:16368075"],"direct_ancestors":[{"relation_name":"is_a","term_name":"NAD+ metabolic process","termid":"GO:0019674"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00522":null,"SJAG_00714":null,"SJAG_01753":null,"SJAG_03306":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0055086","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"malate-aspartate shuttle","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["MetaCyc:MALATE-ASPARTATE-SHUTTLE-PWY","Reactome:R-HSA-9856872","Wikipedia:Malate-aspartate_shuttle"],"synonyms":[{"name":"malate aspartate shuttle","type":"exact"},{"name":"malate/aspartate shuttle","type":"exact"},{"name":"malate:aspartate shuttle","type":"exact"}],"termid":"GO:0043490","terms_by_termid":{"GO:0043490":null}}


id: FYPO:0002580
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature transfer RNA (tRNA) measured in a cell is normal (i.e. indistinguishable from wild type). Total tRNA or a specific tRNA may be measured.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal mature ncRNA level","termid":"FYPO:0006469"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001312","FYPO:0000257","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"normal mature tRNA level","synonyms":[{"name":"normal mature tRNA accumulation","type":"related"},{"name":"normal mature tRNA level during mitotic cell cycle","type":"related"},{"name":"normal mature tRNA level during vegetative growth","type":"exact"},{"name":"normal mature tRNA transcript level","type":"exact"},{"name":"normal mature transfer RNA level","type":"exact"},{"name":"normal tRNA level","type":"broad"}],"termid":"FYPO:0002580"}


id: PBO:0034521
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_telomeric_DNA_separation","termid":"PBO:0034521"}


id: PBO:0060536
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"N-acetyltransferase 16 (putative)","termid":"PBO:0060536"}


id: PBO:0069814
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1100, pseudogene","termid":"PBO:0069814"}


id: PBO:0052590
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"karyopherin subunit alpha 1","termid":"PBO:0052590"}


id: MONDO:0001462
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A malignant neoplasm involving the descending colon.","direct_ancestors":[{"relation_name":"is_a","term_name":"malignant colon neoplasm","termid":"MONDO:0021063"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0004335"],"is_obsolete":false,"name":"descending colon cancer","secondary_identifiers":["ICD9:153.2","ICD10CM:C18.6","MEDGEN:509291","SCTID:363409003","UMLS:C0153435","DOID:12190"],"synonyms":[{"name":"Ca descending colon","type":"exact"},{"name":"cancer of descending colon","type":"exact"},{"name":"descending colon cancer","type":"exact"},{"name":"malignant descending colon neoplasm","type":"exact"},{"name":"malignant neoplasm of descending colon","type":"exact"},{"name":"malignant neoplasm of left colon","type":"exact"},{"name":"malignant tumor of descending colon","type":"exact"},{"name":"malignant tumour of descending colon","type":"exact"}],"termid":"MONDO:0001462","xrefs":{"Monarch":{"xref_id":"0001462"}}}


id: PBO:0120118
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dynamin-related GTPase involved in mitochondrial organization; required for mitochondrial fission and inheritance; self assembles on mitochondrial tubules at incipient division sites; involved in endocytosis; regulates peroxisome fission with Vps1p; role in nuclear envelope remodeling during nucleophagy; mutants in human ortholog DNM1L, which mediates mitochondrial fission, peroxisomal division, autophagy, and mitophagy, are associated with slowly progressive infantile encephalopathy","termid":"PBO:0120118"}


id: MONDO:0012213
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare, complex type of hereditary spastic paraplegia characterized by the onset in childhood/adolescence (ages 2-19) of progressive spastic paraplegia associated mainly with mild to moderate cognitive impairment and developmental delay, cerebellar ataxia, dysarthria, and peripheral neuropathy. Less commonly reported manifestations include skeletal abnormalities (i.e. pes cavus, scoliosis), dyskinesia, dystonia, cataracts, cerebellar signs (i.e. saccadic dysfunction, nystagmus, dysmetria), bladder disturbances, and behavioral problems. SPG26 is caused by mutations in the B4GALNT1 gene (12q13.3), encoding Beta-1, 4 N-acetylgalactosaminyltransferase 1.","definition_xrefs":["Orphanet:101006"],"direct_ancestors":[{"relation_name":"is_a","term_name":"complex hereditary spastic paraplegia","termid":"MONDO:0015150"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"hereditary spastic paraplegia 26","secondary_identifiers":["OMIM:609195","UMLS:C1836632","GARD:9587","DOID:0110777","MEDGEN:373138","MESH:C536862","SCTID:726607007"],"synonyms":[{"name":"GM2 synthase deficiency","type":"exact"},{"name":"SPG26","type":"exact"},{"name":"autosomal recessive spastic paraplegia 26","type":"exact"},{"name":"autosomal recessive spastic paraplegia type 26","type":"exact"},{"name":"hereditary spastic paraplegia type 26","type":"exact"},{"name":"spastic paraplegia 26","type":"related"},{"name":"spastic paraplegia 26, autosomal recessive","type":"related"}],"termid":"MONDO:0012213","xrefs":{"Monarch":{"xref_id":"0012213"}}}


id: PBO:0083066
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dihydrosphingosine phosphate lyase; regulates intracellular levels of sphingolipid long-chain base phosphates (LCBPs), degrades phosphorylated long chain bases, prefers C16 dihydrosphingosine-l-phosphate as a substrate","termid":"PBO:0083066"}


id: GO:0017130
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a sequence of cytosine residues in an RNA molecule.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"poly-pyrimidine tract binding","termid":"GO:0008187"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003723"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0003723","GO:0005488","GO:0003674"],"is_obsolete":false,"name":"poly(C) RNA binding","synonyms":[{"name":"poly(C) binding","type":"broad"},{"name":"poly(rC) binding","type":"exact"}],"termid":"GO:0017130"}


id: PBO:0045371
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DPH5 divergent transcript","termid":"PBO:0045371"}


id: PR:O74442
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- ubp16 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O74442"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin carboxyl-terminal hydrolase 16 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC1682.12c","synonyms":[{"name":"Spom972h-ubp16","type":"exact"},{"name":"deubiquitinating enzyme 16 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"ubiquitin thioesterase 16 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"ubiquitin-specific-processing protease 16 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O74442"}


id: MONDO:0018951
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Distal myopathy with vocal cord and pharyngeal weakness is an adult-onset, autosomal dominant muscular disease which is characterized by muscle weakness in the feet and hands, combined with vocal or swallowing dysfunction.","definition_xrefs":["Orphanet:600"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant distal myopathy","termid":"MONDO:0016108"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"},{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426","MONDO:0005336"],"is_obsolete":false,"name":"distal myopathy with vocal cord weakness","secondary_identifiers":["UMLS:C1853723","icd11.foundation:1133125258","MEDGEN:342950","GARD:1887"],"synonyms":[{"name":"MATR3-related distal myopathy","type":"exact"},{"name":"MPD2","type":"related"},{"name":"VCPDM","type":"exact"},{"name":"distal myopathy 2","type":"related"},{"name":"vocal cord and pharyngeal distal myopathy","type":"related"}],"termid":"MONDO:0018951","xrefs":{"Monarch":{"xref_id":"0018951"}}}


id: MONDO:0013850
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete periodic fever, menstrual cycle-dependent (obsolete MONDO:0013850)","termid":"MONDO:0013850","xrefs":{"Monarch":{"xref_id":"0013850"}}}


id: PBO:0080139
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"VASH1 divergent transcript","termid":"PBO:0080139"}


id: GO:0097224
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. The segment of the sperm flagellum that attaches to the implantation fossa of the nucleus in the sperm head; from the remnant of the centriole at this point, the axoneme extends throughout the length of the flagellum.","definition_xrefs":["MP:0009830","GOC:cjm"],"gene_count":0,"genotype_count":0,"name":"obsolete sperm connecting piece (obsolete GO:0097224)","termid":"GO:0097224"}


id: GO:1903062
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of reverse cholesterol transport.","definition_xrefs":["GOC:rl","GOC:TermGenie","PMID:23931754","GOC:BHF","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cholesterol transport","termid":"GO:0032374"},{"relation_name":"regulates","term_name":"reverse cholesterol transport","termid":"GO:0043691"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0008150"],"is_obsolete":false,"name":"regulation of reverse cholesterol transport","termid":"GO:1903062"}


id: GO:0072733
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a staurosporine stimulus.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to alkaloid","termid":"GO:0043279"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to staurosporine","termid":"GO:0072733"}


id: GO:0048871
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process involved in the maintenance of an internal steady state at the level of the multicellular organism.","definition_xrefs":["GOC:isa_complete"],"direct_ancestors":[{"relation_name":"is_a","term_name":"multicellular organismal process","termid":"GO:0032501"},{"relation_name":"is_a","term_name":"homeostatic process","termid":"GO:0042592"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"multicellular organismal-level homeostasis","termid":"GO:0048871"}


id: GO:0140562
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalyses the reaction: UDP-alpha-D-xylose + [protein with EGF-like domain]-L-serine = UDP + [protein with EGF-like domain]-3-O-(beta-D-xylosyl)-L-serine.","definition_xrefs":["RHEA:62016"],"direct_ancestors":[{"relation_name":"is_a","term_name":"UDP-xylosyltransferase activity","termid":"GO:0035252"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016757"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016757","GO:0003674","GO:0016740"],"is_obsolete":false,"name":"EGF-domain serine xylosyltransferase activity","secondary_identifiers":["EC:2.4.2.63"],"termid":"GO:0140562"}


id: PBO:0042571
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CDKN2A interacting protein N-terminal like","termid":"PBO:0042571"}


id: PBO:0108908
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"KIAA1191 pseudogene 2","termid":"PBO:0108908"}


id: PR:Q9US51
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mtf1 gene.","definition_xrefs":["UniProtKB:Q9US51","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial transcription factor 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1002.08c","synonyms":[{"name":"Spom972h-mtf1","type":"exact"}],"termid":"PR:Q9US51"}


id: PBO:0060113
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-ND6 pseudogene 14","termid":"PBO:0060113"}


id: PBO:0066434
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"regulated endocrine specific protein 18","termid":"PBO:0066434"}


id: GO:0030240
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in skeletal muscle.","definition_xrefs":["GOC:ef","GOC:mtg_muscle","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"actin filament organization","termid":"GO:0007015"},{"relation_name":"part_of","term_name":"skeletal myofibril assembly","termid":"GO:0014866"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0030036"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"part_of","termid":"GO:0007010"}],"interesting_parent_ids":["GO:0044085","GO:0007010","GO:0008150","GO:0030036"],"is_obsolete":false,"name":"skeletal muscle thin filament assembly","termid":"GO:0030240"}


id: GO:0055079
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process involved in the maintenance of an internal steady state of aluminum ions within an organism or cell.","definition_xrefs":["GOC:mah","GOC:jid","GOC:lr"],"gene_count":0,"genotype_count":0,"name":"obsolete aluminum ion homeostasis (obsolete GO:0055079)","synonyms":[{"name":"aluminium ion homeostasis","type":"exact"}],"termid":"GO:0055079"}


id: PR:O42939
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A SUMO-activating enzyme subunit 2 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR10953:SF5","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin-activating enzyme E1-like (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC16H5.03c","secondary_identifiers":["UniProtKB:O42939"],"synonyms":[{"name":"SPBC16H5.03c","type":"related"},{"name":"Spom972h-UBA2","type":"exact"},{"name":"pmt3-activating enzyme subunit 2 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O42939"}


id: FYPO:0001903
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell population phenotype in which the septation index is normal (i.e. indistinguishable from wild type). The septation index is the proportion of the population undergoing septation at any given time, and is usually around 10% (varying between 7-15%) for vegetatively growing wild type cell populations, and less for stationary populations.","definition_xrefs":["PomBase:vw","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell population phenotype","termid":"FYPO:0000003"},{"relation_name":"is_a","term_name":"normal phenotype","termid":"FYPO:0000257"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000003"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0000003"],"is_obsolete":false,"name":"normal septation index","synonyms":[{"name":"normal septation","type":"related"}],"termid":"FYPO:0001903"}


id: PBO:0083768
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Essential non-ATPase regulatory subunit of the 26S proteasome; similar to another S. cerevisiae regulatory subunit, Rpn5p, as well as to mammalian proteasome subunits","termid":"PBO:0083768"}


id: PBO:0002464
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"actin cortical patch component, with EF hand and WH2 motif Panl (predicted)","termid":"PBO:0002464"}


id: PBO:0080812
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"X-ray repair cross complementing 6 pseudogene 2","termid":"PBO:0080812"}


id: GO:0051173
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.","definition_xrefs":["GOC:ai","GOC:tb"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of nitrogen compound metabolic process (obsolete GO:0051173)","synonyms":[{"name":"positive regulation of nitrogen metabolic process","type":"exact"}],"termid":"GO:0051173"}


id: MONDO:0021001
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hemochromatosis type 1 (classic) is the most common form of hereditary hemochromatosis (HH), a group of diseases characterized by excessive tissue iron deposition. Due to its incidence (1/200-1/1000), it is not considered as a rare disease, unlike the other subforms of the disease","definition_xrefs":["EFO:0006513"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete rare hereditary hemochromatosis (obsolete MONDO:0016363)","termid":"MONDO:0016363"},{"relation_name":"is_a","term_name":"hereditary hemochromatosis","termid":"MONDO:0006507"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066"],"is_obsolete":false,"name":"hemochromatosis type 1","secondary_identifiers":["Orphanet:139498","ICD9:275.01","DOID:0111029","OMIM:235200","SCTID:35400008","UMLS:C3469186","NCIT:C84764","MEDGEN:854011"],"synonyms":[{"name":"C282Y/C282Y hemochromatosis","type":"exact"},{"name":"HFE-associated hereditary hemochromatosis","type":"exact"},{"name":"HFE-related hemochromatosis","type":"exact"},{"name":"HFE1","type":"exact"},{"name":"classic hemochromatosis","type":"exact"},{"name":"hemochromatosis","type":"exact"},{"name":"hemochromatosis type 1","type":"exact"},{"name":"hemochromatosis, type 1","type":"exact"},{"name":"hfe hemochromatosis, modifier of","type":"exact"},{"name":"symptomatic form of HFE-related hereditary hemochromatosis","type":"narrow"},{"name":"symptomatic form of classic hemochromatosis","type":"narrow"},{"name":"symptomatic form of hemochromatosis type 1","type":"exact"}],"termid":"MONDO:0021001","xrefs":{"Monarch":{"xref_id":"0021001"}}}


id: PBO:0075643
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sprouty RTK signaling antagonist 2","termid":"PBO:0075643"}


id: MONDO:0017250
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"congenital pulmonary airway malformation","termid":"MONDO:0016580"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"congenital pulmonary airway malformation type 2","secondary_identifiers":["GARD:21095","MEDGEN:1738105","Orphanet:280840","icd11.foundation:1921224131","UMLS:C5437761"],"synonyms":[{"name":"CCAM type 2","type":"exact"},{"name":"CPAM type 2","type":"exact"},{"name":"congenital cystic adenomatoid malformation of the lung type 2","type":"exact"},{"name":"congenital cystic adenomatous malformation of the lung type 2","type":"exact"},{"name":"congenital cystic disease of the lung type 2","type":"exact"}],"termid":"MONDO:0017250","xrefs":{"Monarch":{"xref_id":"0017250"}}}


id: PBO:0045686
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dynein light chain LC8-type 1 pseudogene 6","termid":"PBO:0045686"}


id: GO:0016632
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a cytochrome.","definition_xrefs":["EC:1.3.2.-"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-CH group of donors","termid":"GO:0016627"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"oxidoreductase activity, acting on the CH-CH group of donors, cytochrome as acceptor","termid":"GO:0016632"}


id: GO:0052687
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + ADP + phosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA.","definition_xrefs":["KEGG_REACTION:R06396"],"direct_ancestors":[{"relation_name":"is_a","term_name":"CoA-ligase activity","termid":"GO:0016405"},{"relation_name":"is_a","term_name":"acid-thiol ligase activity","termid":"GO:0016878"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016874"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016874","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity","synonyms":[{"name":"3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity","type":"broad"}],"termid":"GO:0052687"}


id: MONDO:0011004
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"This syndrome is characterized by severe microcephaly, agyria, agenesis of the corpus callosum, cerebellar hypoplasia, facial dysmorphology and epiphyseal stippling of the metacarpal bones. It has been described in two brothers. The syndrome is transmitted as an autosomal recessive trait and may be an allelic variant of Neu-Laxova syndrome and Lissencephaly type III with cystic dilations of the cerebellum and fetal akinesia sequence.","definition_xrefs":["Orphanet:86822"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lissencephaly type 3","termid":"MONDO:0015148"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320"],"is_obsolete":false,"name":"lissencephaly type 3-metacarpal bone dysplasia syndrome","secondary_identifiers":["SCTID:718720007","GARD:16763","MESH:C563383","OMIM:601160","MEDGEN:371379","UMLS:C1832678"],"synonyms":[{"name":"lissencephaly type 3 and bone dysplasia","type":"related"},{"name":"lissencephaly type III and bone dysplasia","type":"related"}],"termid":"MONDO:0011004","xrefs":{"Monarch":{"xref_id":"0011004"}}}


id: MONDO:0008681
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"WAGR syndrome (Wilms tumor - aniridia - genitourinary anomalies - intellectual disability mental retardation) is a rare genetic disorder characterized by an unusual complex of congenital developmental abnormalities with intellectual disability, and an increased risk of developing Wilms tumor.","definition_xrefs":["Orphanet:893"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary neoplastic syndrome","termid":"MONDO:0015356"},{"relation_name":"is_a","term_name":"partial deletion of the short arm of chromosome 11","termid":"MONDO:0016893"},{"relation_name":"is_a","term_name":"46,XY disorder of sex development","termid":"MONDO:0020040"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WAGR syndrome","secondary_identifiers":["DECIPHER:35","NORD:1833","NCIT:C3718","OMIM:194072","UMLS:C0206115","GARD:5528","MESH:D017624","SCTID:715215007","icd11.foundation:1858307812","MEDGEN:64512","DOID:14515"],"synonyms":[{"name":"11p deletion","type":"related"},{"name":"11p deletion syndrome","type":"related"},{"name":"11p monosomy","type":"related"},{"name":"11p partial monosomy syndrome","type":"exact"},{"name":"AGR triad","type":"related"},{"name":"Del(11)(p13)","type":"exact"},{"name":"WAGR","type":"related"},{"name":"WAGR 11p13 deletion syndrome","type":"exact"},{"name":"WAGR Complex","type":"related"},{"name":"WAGR Syndrome/11p Deletion Syndrome","type":"exact"},{"name":"WAGR syndrome","type":"exact"},{"name":"Wilms tumor, aniridia, genitourinary anomalies and developmental delay syndrome","type":"exact"},{"name":"Wilms tumor, aniridia, genitourinary anomalies and mental retardation syndrome, autosomal dominant, somatic mutation","type":"exact"},{"name":"Wilms tumor, aniridia, genitourinary anomalies, and intellectual disability syndrome","type":"related"},{"name":"Wilms tumor, aniridia, genitourinary anomalies, and mental retardation syndrome","type":"related"},{"name":"Wilms tumor, aniridia, genitourinary anomalies, intellectual disability syndrome","type":"related"},{"name":"Wilms tumor, aniridia, genitourinary anomalies, mental retardation syndrome","type":"related"},{"name":"Wilms tumor-aniridia-genitourinary anomalies-intellectual disability syndrome","type":"exact"},{"name":"Wilms tumor-aniridia-genitourinary anomalies-mental retardation syndrome","type":"exact"},{"name":"Wilms tumor-aniridia-gonadoblastoma-intellectual disability syndrome","type":"related"},{"name":"Wilms tumor-aniridia-gonadoblastoma-mental retardation syndrome","type":"related"},{"name":"chromosome 11P13 deletion syndrome","type":"related"},{"name":"chromosome 11p deletion","type":"related"},{"name":"chromosome 11p deletion syndrome","type":"related"},{"name":"chromosome 11p13 deletion syndrome","type":"exact"},{"name":"deletion 11p","type":"related"},{"name":"deletion 11p13","type":"exact"},{"name":"monosomy 11p","type":"related"},{"name":"monosomy 11p13","type":"exact"},{"name":"partial monosomy 11p","type":"related"}],"termid":"MONDO:0008681","xrefs":{"Monarch":{"xref_id":"0008681"}}}


id: PBO:0063134
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"prostate androgen-regulated transcript 1","termid":"PBO:0063134"}


id: GO:1990362
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: butan-1-ol + NAD+ = butanal + H+ + NADH.","definition_xrefs":["RHEA:33199","GOC:mengo_curators","PMID:1999395"],"direct_ancestors":[{"relation_name":"is_a","term_name":"alcohol dehydrogenase (NAD+) activity","termid":"GO:0004022"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"butanol dehydrogenase (NAD+) activity","synonyms":[{"name":"butanol dehydrogenase activity","type":"broad"}],"termid":"GO:1990362"}


id: PBO:0052480
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kelch domain containing 7B","termid":"PBO:0052480"}


id: GO:0062023
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.","definition_xrefs":["GOC:rph","GOC:BHF","PMID:21123617"],"gene_count":0,"genotype_count":0,"name":"obsolete collagen-containing extracellular matrix (obsolete GO:0062023)","synonyms":[{"name":"collagen-containing ECM","type":"exact"}],"termid":"GO:0062023"}


id: MONDO:0100203
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A disease caused by infection with parainfluenza virus type 1.","definition_xrefs":["PMID:27197630","MONDO:patterns/infectious_disease_by_agent"],"direct_ancestors":[{"relation_name":"is_a","term_name":"respirovirus infectious disease","termid":"MONDO:0005940"},{"relation_name":"is_a","term_name":"parainfluenza infectious disease","termid":"MONDO:0100197"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"parainfluenza virus type 1 infectious disease","synonyms":[{"name":"human respirovirus 1 infectious disease","type":"exact"},{"name":"infection caused by human parainfluenza virus 1","type":"exact"},{"name":"infection due to human parainfluenza virus 1","type":"exact"},{"name":"parainfluenza 1 infection","type":"related"}],"termid":"MONDO:0100203","xrefs":{"Monarch":{"xref_id":"0100203"}}}


id: PBO:0044791
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"defensin alpha 4","termid":"PBO:0044791"}


id: SO:0000735
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"The location of a sequence.","direct_ancestors":[{"relation_name":"is_a","term_name":"sequence_attribute","termid":"SO:0000400"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sequence_location","synonyms":[{"name":"sequence location","type":"exact"}],"termid":"SO:0000735"}


id: FYPO:0001883
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing caspofungin.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal growth on echinocandin","termid":"FYPO:0004892"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0000003"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0000003","FYPO:0002058","FYPO:0000139","FYPO:0002057","FYPO:0002060"],"is_obsolete":false,"name":"normal growth on caspofungin","synonyms":[{"name":"normal cell population growth in presence of caspofungin","type":"exact"},{"name":"normal cell population growth on caspofungin","type":"exact"},{"name":"normal cell population growth on glucan synthase inhibitor","type":"broad"},{"name":"normal cellular response to caspofungin","type":"related"},{"name":"normal vegetative cell population growth on caspofungin","type":"exact"}],"termid":"FYPO:0001883"}


id: PBO:0030406
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-Glc3Man9GlcNAc_absent_from_cell","termid":"PBO:0030406"}


id: PBO:0079459
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"trans-golgi network vesicle protein 23 homolog A","termid":"PBO:0079459"}


id: PBO:0089567
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rab GEF Sec2","termid":"PBO:0089567"}


id: PBO:0092030
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA Tyrosine (gua), mitochondrial","termid":"PBO:0092030"}


id: PBO:0000588
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"alpha-1,2-mannosyltransferase (predicted)","termid":"PBO:0000588"}


id: GO:1990388
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of iron ions into the phloem from the xylem.","definition_xrefs":["GOC:tb","PMID:24867923"],"direct_ancestors":[{"relation_name":"is_a","term_name":"iron ion transport","termid":"GO:0006826"},{"relation_name":"is_a","term_name":"phloem transport","termid":"GO:0010233"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0051179","GO:0006810"],"is_obsolete":false,"name":"xylem-to-phloem iron transport","termid":"GO:1990388"}


id: GO:0009787
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of abscisic acid (ABA) signaling.","definition_xrefs":["GOC:lr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of signal transduction","termid":"GO:0009966"},{"relation_name":"is_a","term_name":"regulation of cellular response to alcohol","termid":"GO:1905957"},{"relation_name":"regulates","term_name":"abscisic acid-activated signaling pathway","termid":"GO:0009738"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"regulation of abscisic acid-activated signaling pathway","synonyms":[{"name":"regulation of abscisic acid mediated signaling pathway","type":"related"},{"name":"regulation of abscisic acid mediated signalling","type":"exact"}],"termid":"GO:0009787"}


id: GO:0006451
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The continuation of translation beyond a stop codon by the use of a special tRNA that recognizes the UAG and UGA codons as modified amino acids, rather than as termination codons.","definition_xrefs":["PMID:11179232","GOC:jsg"],"direct_ancestors":[{"relation_name":"is_a","term_name":"translational elongation","termid":"GO:0006414"},{"relation_name":"is_a","term_name":"regulation of translation","termid":"GO:0006417"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"translational readthrough","synonyms":[{"name":"natural nonsense suppression","type":"related"}],"termid":"GO:0006451"}


id: MONDO:1011068
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Urolithiasis that occurs in Silvery lutung.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"urolithiasis, non-human animal","termid":"MONDO:1010267"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"urolithiasis, Silvery lutung","secondary_identifiers":["OMIA:001033-122765"],"termid":"MONDO:1011068","xrefs":{"Monarch":{"xref_id":"1011068"}}}


id: PBO:0030394
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-binucleate_multiseptate_vegetative_cell","termid":"PBO:0030394"}


id: GO:0018418
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The incorporation of nickel into a 3Fe-2S complex by tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide.","definition_xrefs":["RESID:AA0293"],"direct_ancestors":[{"relation_name":"is_a","term_name":"iron-sulfur cluster assembly","termid":"GO:0016226"},{"relation_name":"is_a","term_name":"peptidyl-cysteine modification","termid":"GO:0018198"},{"relation_name":"is_a","term_name":"peptidyl-glutamic acid modification","termid":"GO:0018200"},{"relation_name":"is_a","term_name":"peptidyl-histidine modification","termid":"GO:0018202"},{"relation_name":"is_a","term_name":"nickel incorporation into metallo-sulfur cluster","termid":"GO:0018414"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016226"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0008150","GO:0044085","GO:0016226"],"is_obsolete":false,"name":"nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide","synonyms":[{"name":"nickel incorporation into iron-sulphur cluster via tris-L-cysteinyl L-cysteine persulphido L-glutamato L-histidino L-serinyl nickel triiron disulphide trioxide","type":"exact"}],"termid":"GO:0018418"}


id: PBO:0088178
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Zeta subunit of the oligosaccharyltransferase complex of the ER lumen; complex catalyzes asparagine-linked glycosylation of newly synthesized proteins","termid":"PBO:0088178"}


id: MONDO:0018867
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete maple syrup urine disease (obsolete MONDO:0018867)","termid":"MONDO:0018867","xrefs":{"Monarch":{"xref_id":"0018867"}}}


id: PBO:0047135
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 172 member A","termid":"PBO:0047135"}


id: MONDO:0008670
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Waardenburg syndrome type 1 (WS1) is a subtype of Waardenburg syndrome (WS), disorder characterized by congenital deafness, minor defects in structures arising from neural crest resulting in pigmentation anomalies of eyes, hair, and skin, in combination with dystopia canthorum.","definition_xrefs":["Orphanet:894"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Waardenburg syndrome","termid":"MONDO:0018094"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426"],"is_obsolete":false,"name":"Waardenburg syndrome type 1","secondary_identifiers":["OMIM:193500","icd11.foundation:547536187","ICD10CM:E70.3","MEDGEN:376211","DOID:0110948","GARD:5519","NCIT:C75008","UMLS:C1847800"],"synonyms":[{"name":"WS1","type":"exact"},{"name":"Waardenburg syndrome type 1","type":"exact"},{"name":"Waardenburg syndrome type I","type":"exact"},{"name":"Waardenburg syndrome with dystopia canthorum","type":"related"},{"name":"Waardenburg syndrome, type 1","type":"related"},{"name":"Waardenburg's syndrome type 1","type":"related"}],"termid":"MONDO:0008670","xrefs":{"Monarch":{"xref_id":"0008670"}}}


id: PBO:0000649
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA-directed RNA polymerase I and III subunit Rpc19","termid":"PBO:0000649"}


id: PBO:0091046
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vacuolar phytochelatin and glutathione S-conjugate ABC family transmembrane transporter Abc4","termid":"PBO:0091046"}


