# terms

id: MONDO:0100287
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An autosomal dominant hereditary syndrome caused by germline pathogenic POLE variants. It is characterized by the presence of colorectal polyps and colorectal cancer.","direct_ancestors":[{"relation_name":"is_a","term_name":"polyposis","termid":"MONDO:0000147"},{"relation_name":"is_a","term_name":"Polymerase proofreading-related adenomatous polyposis","termid":"MONDO:0018653"},{"relation_name":"is_a","term_name":"polyp of large intestine","termid":"MONDO:0021392"},{"relation_name":"is_a","term_name":"familial colorectal cancer","termid":"MONDO:0023113"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0004335"],"is_obsolete":false,"name":"POLE-related polyposis and colorectal cancer syndrome","termid":"MONDO:0100287","xrefs":{"Monarch":{"xref_id":"0100287"}}}


id: PATO:0001102
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0001102 absolute stiffness value (obsolete PATO:0001102)","termid":"PATO:0001102"}


id: PBO:0029308
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-swollen_spheroid_cell_during_G0","termid":"PBO:0029308"}


id: MONDO:0008649
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"venular insufficiency, systemic","secondary_identifiers":["UMLS:C1860465","MEDGEN:348623","OMIM:192700","MESH:C566004"],"synonyms":[{"name":"venular insufficiency, systemic","type":"exact"}],"termid":"MONDO:0008649","xrefs":{"Monarch":{"xref_id":"0008649"}}}


id: MONDO:0037939
data:
  {"annotated_genes":["SJAG_02876","SJAG_04944","SJAG_01372","SJAG_03961","SJAG_02896","SJAG_05283","SJAG_01841","SJAG_04109"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87099],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008294"},{"annotations":[87243],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009902"},{"annotations":[87499],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008296"},{"annotations":[87198],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0030048"},{"annotations":[87652],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007369"},{"annotations":[87244],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013000"},{"annotations":[86935],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008319"},{"annotations":[87518],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008297"},{"annotations":[88170],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0957577"},{"annotations":[88514],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010420"}]},"cv_name":"mondo","definition":"Porphyria is a group of diseases in which substances called porphyrins build up, negatively affecting the skin or nervous system. Most types are inherited, but porphyria cutanea tarda may also be due to increased iron in the liver, hepatitis C, alcohol, or HIV/AIDS.","definition_xrefs":["Wikipedia:Porphyria"],"direct_ancestors":[{"relation_name":"is_a","term_name":"porphyrin metabolism disease","termid":"MONDO:0037821"}],"gene_count":8,"genes_by_uniquename":{"SJAG_01372":null,"SJAG_01841":null,"SJAG_02876":null,"SJAG_02896":null,"SJAG_03961":null,"SJAG_04109":null,"SJAG_04944":null,"SJAG_05283":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066"],"is_obsolete":false,"name":"porphyria","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1844832","NANDO:1200811","SCTID:418470004","UMLS:C5848305","MESH:D011164","NCIT:C97096"],"synonyms":[{"name":"porphyria","type":"exact"}],"termid":"MONDO:0037939","terms_by_termid":{"MONDO:0007369":null,"MONDO:0008294":null,"MONDO:0008296":null,"MONDO:0008297":null,"MONDO:0008319":null,"MONDO:0009902":null,"MONDO:0010420":null,"MONDO:0013000":null,"MONDO:0030048":null,"MONDO:0957577":null},"xrefs":{"Monarch":{"xref_id":"0037939"}}}


id: GO:0038153
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals initiated by the binding of the C-C chemokine CCL2 to a C-C chemokine type 4 receptor (CCR4) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.","definition_xrefs":["GOC:signaling","GOC:nhn"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chemokine (C-C motif) ligand 2 signaling pathway","termid":"GO:0038148"},{"relation_name":"is_a","term_name":"C-C chemokine receptor CCR4 signaling pathway","termid":"GO:0038152"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"CCL2-activated CCR4 signaling pathway","synonyms":[{"name":"CCL2/CCR4 signaling pathway","type":"related"}],"termid":"GO:0038153"}


id: PBO:0091556
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"But2 family protein, similar to cell surface molecules","termid":"PBO:0091556"}


id: MONDO:0014620
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any myoclonus-dystonia syndrome in which the cause of the disease is a mutation in the KCTD17 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myoclonus-dystonia syndrome","termid":"MONDO:0000903"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0003441"}],"interesting_parent_ids":["MONDO:0003441"],"is_obsolete":false,"name":"myoclonic dystonia 26","secondary_identifiers":["GARD:16103","OMIM:616398","MEDGEN:904244","UMLS:C4225341","DOID:0090036"],"synonyms":[{"name":"DYT26","type":"related"},{"name":"KCTD17 myoclonus-dystonia syndrome","type":"exact"},{"name":"dystonia 26, myoclonic","type":"related"},{"name":"myoclonic dystonia type 26","type":"exact"},{"name":"myoclonus-dystonia syndrome caused by mutation in KCTD17","type":"exact"}],"termid":"MONDO:0014620","xrefs":{"Monarch":{"xref_id":"0014620"}}}


id: GO:1905814
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of motor neuron axon guidance.","definition_xrefs":["GO_REF:0000058","GOC:TermGenie","PMID:18434533"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of axon guidance","termid":"GO:1902669"},{"relation_name":"is_a","term_name":"regulation of motor neuron axon guidance","termid":"GO:1905812"},{"relation_name":"positively_regulates","term_name":"motor neuron axon guidance","termid":"GO:0008045"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of motor neuron axon guidance","synonyms":[{"name":"activation of motoneuron axon guidance","type":"narrow"},{"name":"activation of motor axon guidance","type":"narrow"},{"name":"activation of motor axon pathfinding","type":"narrow"},{"name":"activation of motor neuron axon guidance","type":"narrow"},{"name":"positive regulation of motoneuron axon guidance","type":"exact"},{"name":"positive regulation of motor axon guidance","type":"exact"},{"name":"positive regulation of motor axon pathfinding","type":"exact"},{"name":"up regulation of motoneuron axon guidance","type":"exact"},{"name":"up regulation of motor axon guidance","type":"exact"},{"name":"up regulation of motor axon pathfinding","type":"exact"},{"name":"up regulation of motor neuron axon guidance","type":"exact"},{"name":"up-regulation of motoneuron axon guidance","type":"exact"},{"name":"up-regulation of motor axon guidance","type":"exact"},{"name":"up-regulation of motor axon pathfinding","type":"exact"},{"name":"up-regulation of motor neuron axon guidance","type":"exact"},{"name":"upregulation of motoneuron axon guidance","type":"exact"},{"name":"upregulation of motor axon guidance","type":"exact"},{"name":"upregulation of motor axon pathfinding","type":"exact"},{"name":"upregulation of motor neuron axon guidance","type":"exact"}],"termid":"GO:1905814"}


id: MONDO:0019850
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete precocious puberty (obsolete MONDO:0019850)","termid":"MONDO:0019850","xrefs":{"Monarch":{"xref_id":"0019850"}}}


id: PBO:0077147
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transketolase","termid":"PBO:0077147"}


id: PBO:0061836
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"opioid growth factor receptor","termid":"PBO:0061836"}


id: PBO:0081697
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 619 pseudogene 1","termid":"PBO:0081697"}


id: GO:0072103
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of the glomerulus vasculature are generated and organized. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"blood vessel morphogenesis","termid":"GO:0048514"},{"relation_name":"is_a","term_name":"kidney vasculature morphogenesis","termid":"GO:0061439"},{"relation_name":"part_of","term_name":"glomerulus vasculature development","termid":"GO:0072012"},{"relation_name":"part_of","term_name":"glomerulus morphogenesis","termid":"GO:0072102"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"glomerulus vasculature morphogenesis","termid":"GO:0072103"}


id: MONDO:0042960
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Sackey-Sakati-Aur syndrome","secondary_identifiers":["MEDGEN:444056","MESH:C537219","UMLS:C2931442"],"synonyms":[{"name":"Aur syndrome","type":"related"},{"name":"Sackey Sakati Aur syndrome","type":"related"},{"name":"multiple dysmorphic features and pancytopenia","type":"related"},{"name":"pancytopenia multiple congenital anomalies","type":"related"}],"termid":"MONDO:0042960","xrefs":{"Monarch":{"xref_id":"0042960"}}}


id: PBO:0065666
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PTPRN2 antisense RNA 1","termid":"PBO:0065666"}


id: SO:0000694
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"SNPs are single base pair positions in genomic DNA at which different sequence alternatives exist in normal individuals in some population(s), wherein the least frequent variant has an abundance of 1% or greater.","definition_xrefs":["SO:cb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"SNV","termid":"SO:0001483"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SNP","synonyms":[{"name":"single nucleotide polymorphism","type":"exact"}],"termid":"SO:0000694"}


id: MONDO:0011694
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Spinocerebellar ataxia type 15/16 (SCA15/16) is a rare subtype of type I autosomal dominant cerebellar ataxia (ADCA type I). It is characterized by cerebellar ataxia, tremor and cognitive impairment.","definition_xrefs":["Orphanet:98769"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant cerebellar ataxia type I","termid":"MONDO:0019792"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0002039"}],"interesting_parent_ids":["MONDO:0005559","MONDO:0002039","MONDO:0000426"],"is_obsolete":false,"name":"spinocerebellar ataxia type 15/16","secondary_identifiers":["Orphanet:98770","SCTID:716724006","GARD:10477","DOID:0050966","DOID:0050965","MESH:C564685","MEDGEN:338301","NCIT:C150250","UMLS:C1847725","OMIM:606658"],"synonyms":[{"name":"SCA15","type":"related"},{"name":"SCA15/16","type":"exact"},{"name":"SCA16 (formerly)","type":"related"},{"name":"SCAR16","type":"exact"},{"name":"spinocerebellar ataxia 15","type":"related"},{"name":"spinocerebellar ataxia 16","type":"related"},{"name":"spinocerebellar ataxia 16 (formerly)","type":"related"},{"name":"spinocerebellar ataxia 16, formerly","type":"related"},{"name":"spinocerebellar ataxia type 15","type":"exact"},{"name":"spinocerebellar ataxia type 15/16","type":"exact"},{"name":"spinocerebellar ataxia type 16","type":"exact"}],"termid":"MONDO:0011694","xrefs":{"Monarch":{"xref_id":"0011694"}}}


id: FYPO:0004808
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein present as aggregates of misfolded protein is greater than normal during a cellular response to heat.","definition_xrefs":["PMID:25543137","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased protein level during cellular response to heat","termid":"FYPO:0003152"},{"relation_name":"is_a","term_name":"increased cellular protein aggregate level","termid":"FYPO:0004180"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0005447","FYPO:0006551","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"increased cellular protein aggregate level during cellular response to heat","synonyms":[{"name":"increased cellular protein aggregate level during cellular response to heat during mitotic cell cycle","type":"related"},{"name":"increased cellular protein aggregate level during cellular response to heat during vegetative growth","type":"exact"}],"termid":"FYPO:0004808"}


id: FYPO:0000699
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which DNA-7-methylguanine glycosylase activity is absent.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished catalytic activity","termid":"FYPO:0000664"},{"relation_name":"is_a","term_name":"abnormal DNA-7-methylguanine glycosylase activity","termid":"FYPO:0000697"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000652","FYPO:0000661","FYPO:0000707","FYPO:0000654","FYPO:0001985"],"is_obsolete":false,"name":"abolished DNA-7-methylguanine glycosylase activity","synonyms":[{"name":"DNA-7-methylguanine glycosylase activity abolished","type":"exact"}],"termid":"FYPO:0000699"}


id: PBO:0039588
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"anoctamin 6","termid":"PBO:0039588"}


id: PBO:0108511
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Clr6 and Rpd3L histone deacetylase complex subunit Sds3","termid":"PBO:0108511"}


id: PBO:0036238
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"conserved eukaryotic protein, human c22orf39 ortholog","termid":"PBO:0036238"}


id: PBO:0035791
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_histone_H2B-K119_ubiquitination_at_double-strand_break_site_during_vegetative_growth","termid":"PBO:0035791"}


id: FYPO:0006226
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to spermidine. Cells stop growing (and may die) at a concentration of spermidine that allows wild type cells to grow.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased sensitivity to chemical during vegetative growth","termid":"FYPO:0000127"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0002683"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000003"}],"interesting_parent_ids":["FYPO:0000003","FYPO:0005447","FYPO:0000139","FYPO:0002683","FYPO:0001985"],"is_obsolete":false,"name":"sensitive to spermidine","synonyms":[{"name":"hypersensitive to spermidine","type":"exact"},{"name":"sensitive to spermidine during mitotic cell cycle","type":"related"},{"name":"sensitive to spermidine during vegetative growth","type":"exact"}],"termid":"FYPO:0006226"}


id: PBO:0069499
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 766, pseudogene","termid":"PBO:0069499"}


id: FYPO:0007769
data:
  {"alleles_by_uniquename":{"SJAG_03892:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_03892","name":"vps4delta","uniquename":"SJAG_03892:allele-1"}},"annotation_feature_type":"genotype","cv_annotations":{"single_locus_phenotype":[{"annotations":[121284],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0007770"}]},"cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin tethering at the nuclear periphery persists after the onset of mitosis. Normally, heterochromatic parts of chromosomes, such as centromeres and telomeres, are maintained at the nuclear periphery during interphase and released during mitosis.","definition_xrefs":["PomBase:mah","PMID:32109380"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal heterochromatin tethering at nuclear periphery","termid":"FYPO:0007768"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03892":null},"genotype_count":1,"genotypes_by_uniquename":{"vps4delta":{"display_name":"vps4delta","display_uniquename":"vps4delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_03892:allele-1","expression":"Null"}]}]}},"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000138"],"is_obsolete":false,"name":"increased heterochromatin tethering at nuclear periphery during mitosis","references_by_uniquename":{"PMID:32109380":null},"single_locus_annotated_genes":["SJAG_03892"],"single_locus_genotype_uniquenames":["vps4delta"],"synonyms":[{"name":"increased heterochromatin anchoring at nuclear periphery during mitosis","type":"exact"},{"name":"increased heterochromatin tethering at nuclear periphery during mitosis during mitotic cell cycle","type":"related"},{"name":"increased heterochromatin tethering at nuclear periphery during mitosis during vegetative growth","type":"exact"},{"name":"increased heterochromatin tethering at nuclear periphery during mitotic M phase","type":"related"},{"name":"increased heterochromatin tethering at nuclear periphery during mitotic nuclear division","type":"exact"}],"termid":"FYPO:0007769","terms_by_termid":{"FYPO:0007770":null,"FYPO_EXT:0000001":null}}


id: PBO:0042351
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CD84 pseudogene 1","termid":"PBO:0042351"}


id: GO:0008963
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine = Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + UMP.","definition_xrefs":["RHEA:21920"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphotransferase activity, for other substituted phosphate groups","termid":"GO:0016780"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016780"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016740","GO:0003824","GO:0016780"],"is_obsolete":false,"name":"phospho-N-acetylmuramoyl-pentapeptide-transferase activity","secondary_identifiers":["MetaCyc:RXN-8975"],"synonyms":[{"name":"MraY transferase activity","type":"narrow"},{"name":"UDP-MurAc(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala):undecaprenyl-phosphate phospho-N-acetylmuramoyl-pentapeptide-transferase activity","type":"related"},{"name":"UDP-MurNAc-Ala-gamma-DGlu-Lys-DAla-DAla:undecaprenylphosphate transferase activity","type":"related"},{"name":"UDP-MurNAc-Ala-gammaDGlu-Lys-DAla-DAla:undecaprenylphosphate transferase activity","type":"related"},{"name":"UDP-MurNAc-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala:C(55)-isoprenoid alcohol transferase activity","type":"related"},{"name":"UDP-MurNAc-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala:C55-isoprenoid alcohol transferase activity","type":"related"},{"name":"UDP-MurNAc-pentapeptide phosphotransferase activity","type":"related"},{"name":"phospho-MurNAc-pentapeptide transferase activity","type":"related"},{"name":"phospho-N-acetylmuramoyl pentapeptide translocase activity","type":"related"},{"name":"phospho-NAc-muramoyl-pentapeptide translocase (UMP) activity","type":"related"},{"name":"phosphoacetylmuramoylpentapeptide translocase activity","type":"related"},{"name":"phosphoacetylmuramoylpentapeptidetransferase activity","type":"related"}],"termid":"GO:0008963"}


id: MONDO:0020761
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A form of squamous cell carcinoma in situ. It is a distinct clinicopathological entity and arises from the skin or the mucocutaneous junction. It affects predominantly white males in their 6-8th decades of life. Exposed and non-exposed skin sites are equally affected. UV damage and ingestion of inorganic arsenic may play a role in the development of the disease. On the skin surface, it presents as a single or multiple erythematous, scaly, keratotic patches or plaques. The clinical entity of erythroplasia of Queyrat is regarded as Bowen disease of the penis and it presents as an asymptomatic, red, circumscribed plaque. Morphologically, Bowen disease is characterized by the presence of hyperkeratosis, parakeratosis, dyskeratosis, and acanthosis. The keratotic squamous cells are atypical and display hyperchromatism and abnormal mitotic figures. The dermoepidermal basement membrane is intact. Complete surgical removal of the lesion may be curative.","definition_xrefs":["NCIT:C62571"],"direct_ancestors":[{"relation_name":"is_a","term_name":"skin squamous cell carcinoma in situ","termid":"MONDO:0020760"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"},{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0005093"],"is_obsolete":false,"name":"Bowen disease of the skin","secondary_identifiers":["ICDO:8081/2","MESH:D001913","MEDGEN:14207","NORD:868","UMLS:C0006079"],"synonyms":[{"name":"Bowen Disease","type":"exact"},{"name":"Bowen disease","type":"exact"},{"name":"Bowen disease of the skin","type":"exact"},{"name":"Bowen's disease of the skin","type":"exact"},{"name":"Bowens Disease","type":"exact"},{"name":"Disease, Bowen","type":"exact"},{"name":"Disease, Bowen's","type":"exact"},{"name":"intraepidermal squamous cell carcinoma, Bowen type","type":"exact"}],"termid":"MONDO:0020761","xrefs":{"Monarch":{"xref_id":"0020761"}}}


id: GO:0098724
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Symmetric division of a stem cell to produce two stem cells of the same type as the parent. Symmetric stem cell division is necessary for amplification of stem cell populations in the absence of sources of stem cells external to an existing population.","definition_xrefs":["PMID:23303905","PMID:19948499"],"direct_ancestors":[{"relation_name":"is_a","term_name":"stem cell division","termid":"GO:0017145"},{"relation_name":"is_a","term_name":"symmetric cell division","termid":"GO:0098725"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"symmetric stem cell division","termid":"GO:0098724"}


id: GO:0072090
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population, that contributes to the shaping of a nephron.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mesenchymal stem cell proliferation","termid":"GO:0097168"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mesenchymal stem cell proliferation involved in nephron morphogenesis","termid":"GO:0072090"}


id: FYPO:0000962
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing hydrogen peroxide.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal vegetative cell population growth","termid":"FYPO:0001357"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0002057"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0002057","FYPO:0000139","FYPO:0002060","FYPO:0000003","FYPO:0002058"],"is_obsolete":false,"name":"normal growth on hydrogen peroxide","synonyms":[{"name":"normal cell population growth in presence of hydrogen peroxide","type":"exact"},{"name":"normal cell population growth on H2O2","type":"exact"},{"name":"normal cell population growth on hydrogen peroxide","type":"exact"},{"name":"normal cellular response to hydrogen peroxide","type":"related"},{"name":"normal vegetative cell population growth on hydrogen peroxide","type":"exact"}],"termid":"FYPO:0000962"}


id: FYPO:0004048
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of glutathione peroxidase activity is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal cellular process","termid":"FYPO:0000628"},{"relation_name":"is_a","term_name":"abnormal oxidoreductase activity","termid":"FYPO:0000689"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000707"}],"interesting_parent_ids":["FYPO:0000707","FYPO:0001985","FYPO:0000654","FYPO:0005447","FYPO:0000002","FYPO:0000661","FYPO:0000652"],"is_obsolete":false,"name":"abnormal glutathione peroxidase activity","termid":"FYPO:0004048"}


id: GO:0033139
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of peptidyl-serine phosphorylation","termid":"GO:0033135"},{"relation_name":"regulates","term_name":"serine phosphorylation of STAT protein","termid":"GO:0042501"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of peptidyl-serine phosphorylation of STAT protein","secondary_identifiers":["GO:1903261"],"synonyms":[{"name":"regulation of serine phosphorylation of STAT3 protein","type":"narrow"}],"termid":"GO:0033139"}


id: MONDO:0011523
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Bardet-Biedl syndrome","termid":"MONDO:0015229"},{"relation_name":"is_a","term_name":"MKKS-related ciliopathy","termid":"MONDO:1040050"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0006025"],"is_obsolete":false,"name":"Bardet-Biedl syndrome 6","secondary_identifiers":["GARD:10205","MESH:C565738","OMIM:605231","UMLS:C1858054","MEDGEN:347610","DOID:0110128"],"synonyms":[{"name":"BBS6","type":"exact"},{"name":"Bardet-Biedl syndrome 6","type":"exact"},{"name":"Bardet-Biedl syndrome type 6","type":"exact"}],"termid":"MONDO:0011523","xrefs":{"Monarch":{"xref_id":"0011523"}}}


id: MONDO:1010921
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Myositis ossificans that occurs in cattle.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myositis ossificans, non-human animal","termid":"MONDO:1010197"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myositis ossificans, cattle","secondary_identifiers":["OMIA:000697-9913"],"termid":"MONDO:1010921","xrefs":{"Monarch":{"xref_id":"1010921"}}}


id: FYPO:0003519
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of hercynylcysteine sulfoxide measured in a cell is higher than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased level of substance in cell during vegetative growth","termid":"FYPO:0001330"},{"relation_name":"is_a","term_name":"increased cellular hercynylcysteine sulfoxide level","termid":"FYPO:0003522"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"increased cellular hercynylcysteine sulfoxide level during vegetative growth","synonyms":[{"name":"increased cellular hercynylcysteine sulfoxide level during mitotic cell cycle","type":"related"},{"name":"increased cellular hercynylcysteine sulphoxide level during vegetative growth","type":"exact"},{"name":"increased hercynylcysteine sulfoxide level during vegetative growth","type":"exact"}],"termid":"FYPO:0003519"}


id: SO:0001959
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A cis-regulatory element, conserved sequence YYC+1TTTYY, and spans -2 to +6 relative to +1 TSS. It is present in most ribosomal protein genes in Drosophila and mammals but not in the yeast Saccharomyces cerevisiae. Resembles the initiator (TCAKTY in Drosophila) but functionally distinct from initiator.","definition_xrefs":["SO:myl","PMID:20801935"],"direct_ancestors":[{"relation_name":"is_a","term_name":"core_eukaryotic_promoter_element","termid":"SO:0001660"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TCT_motif","synonyms":[{"name":"TCT element","type":"exact"},{"name":"polypyrimidine initiator","type":"exact"}],"termid":"SO:0001959"}


id: PBO:0064552
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"POM121 transmembrane nucleoporin like 14, pseudogene","termid":"PBO:0064552"}


id: MONDO:0003468
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A synovial sarcoma characterized by the presence of both an epithelial and a spindle cell component.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"synovial sarcoma","termid":"MONDO:0010434"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"biphasic synovial sarcoma","secondary_identifiers":["ICDO:9043/3","DOID:5492","UMLS:C0334507","MEDGEN:137773","NCIT:C4279"],"synonyms":[{"name":"biphasic sarcoma of synovium","type":"exact"},{"name":"biphasic sarcoma of the synovium","type":"exact"},{"name":"synovial sarcoma, biphasic","type":"exact"},{"name":"synovial sarcoma, biphasic (morphologic abnormality)","type":"exact"}],"termid":"MONDO:0003468","xrefs":{"Monarch":{"xref_id":"0003468"}}}


id: FYPO:0004345
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at long terminal repeats is decreased.","definition_xrefs":["PMID:25002536","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased protein localization to chromatin during vegetative growth","termid":"FYPO:0002909"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001320","FYPO:0000138","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"decreased protein localization to chromatin at long terminal repeat","synonyms":[{"name":"decreased protein localisation to chromatin at long terminal repeat","type":"exact"},{"name":"decreased protein localization to chromatin at LTR","type":"exact"},{"name":"decreased protein localization to chromatin at long terminal repeat during mitotic cell cycle","type":"related"},{"name":"decreased protein localization to chromatin at long terminal repeat during vegetative growth","type":"exact"},{"name":"reduced protein localization to chromatin at long terminal repeat","type":"exact"}],"termid":"FYPO:0004345"}


id: GO:0061563
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process that contributes to creating the structural organization of the trigeminal ganglion This process pertains to the physical shaping of a rudimentary structure.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cranial ganglion structural organization","termid":"GO:0061562"},{"relation_name":"part_of","term_name":"trigeminal nerve structural organization","termid":"GO:0021637"},{"relation_name":"part_of","term_name":"trigeminal ganglion morphogenesis","termid":"GO:0061556"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"trigeminal ganglion structural organization","synonyms":[{"name":"trigeminal ganglia organization","type":"related"}],"termid":"GO:0061563"}


id: PBO:0063225
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protocadherin 10","termid":"PBO:0063225"}


id: PATO:0000830
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000830 relative visual ability value (obsolete PATO:0000830)","termid":"PATO:0000830"}


id: PBO:0040166
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acetylserotonin O-methyltransferase like","termid":"PBO:0040166"}


id: GO:0071416
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tropane stimulus. Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to tropane","termid":"GO:0014073"},{"relation_name":"is_a","term_name":"cellular response to alkaloid","termid":"GO:0071312"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to tropane","termid":"GO:0071416"}


id: PBO:0110337
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"beta-1,4-N-acetyl-galactosaminyltransferase 2 (SID blood group)","termid":"PBO:0110337"}


id: MONDO:0014890
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any cold-induced sweating syndrome in which the cause of the disease is a mutation in the KLHL7 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cold-induced sweating syndrome","termid":"MONDO:0015526"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0005244"],"is_obsolete":false,"name":"PERCHING syndrome","secondary_identifiers":["UMLS:C4310742","MEDGEN:934709","DOID:0080331","GARD:18278","OMIM:617055","Orphanet:603684"],"synonyms":[{"name":"CISS3","type":"exact"},{"name":"CRISPONI/cold-induced sweating syndrome 3","type":"related"},{"name":"Crisponi/cold-induced sweating syndrome 3","type":"related"},{"name":"KLHL7 cold-induced sweating syndrome","type":"exact"},{"name":"KLHL7-related bohring-opitz-like/cold-induced sweating-like overlap syndrome","type":"exact"},{"name":"PERCHING","type":"exact"},{"name":"Postural and Palatal abnormalities; Exophthalmos and Enteral-tube dependency/feeding issues; Respiratory distress and Retinitis pigmentosa; Contractures and Camptodactyly; Hypertelorism and Hirsutism; Intrauterine growth retardation (IUGR)/growth failure and Intellectual disability/developmental delay; Nevus flammeus and Neurologic malformations;and facial Gestalt/grimacing and Genitourinary abnormalities","type":"exact"},{"name":"cold-induced sweating syndrome 3","type":"exact"},{"name":"cold-induced sweating syndrome caused by mutation in KLHL7","type":"exact"},{"name":"cold-induced sweating syndrome type 3","type":"exact"}],"termid":"MONDO:0014890","xrefs":{"Monarch":{"xref_id":"0014890"}}}


id: PBO:0072598
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"regulator of solute carriers 1","termid":"PBO:0072598"}


id: PBO:0082929
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cytoplasmic and mitochondrial alanyl-tRNA synthetase; required for protein synthesis; point mutation (cdc64-1 allele) causes cell cycle arrest at G1; lethality of null mutation is functionally complemented by human homolog AARS; mutations in human homolog AARS are associated with autoimmune disease polymyositis/dermatomyositis and with hereditary peripheral neuropathy, Charcot-Marie-Tooth (CMT) disease","termid":"PBO:0082929"}


id: GO:0044185
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The lipid bilayer surrounding a host cell late endosome.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"host cell endosome membrane","termid":"GO:0044175"},{"relation_name":"part_of","term_name":"host cell late endosome","termid":"GO:0044184"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"host cell late endosome membrane","termid":"GO:0044185"}


id: PBO:0069933
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1226, pseudogene","termid":"PBO:0069933"}


id: GO:0021902
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The commitment of neuronal precursor cells to become specialized types of neurons in the forebrain.","definition_xrefs":["GOC:cls","PMID:16226447","GO_REF:0000021","GOC:dgh","GOC:dph","GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"forebrain neuron fate commitment","termid":"GO:0021877"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"commitment of neuronal cell to specific neuron type in forebrain","termid":"GO:0021902"}


id: PBO:0073771
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 4 member 4","termid":"PBO:0073771"}


id: PBO:0059867
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myotubularin related protein 4","termid":"PBO:0059867"}


id: GO:0061944
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of K48-linked ubiquitination, a protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.","definition_xrefs":["GOC:BHF","PMID:23460740","GOC:rph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of protein K48-linked ubiquitination","termid":"GO:0061945"},{"relation_name":"is_a","term_name":"negative regulation of protein polyubiquitination","termid":"GO:1902915"},{"relation_name":"negatively_regulates","term_name":"protein K48-linked ubiquitination","termid":"GO:0070936"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0070647"},{"rel_name":"negatively_regulates","termid":"GO:0070647"}],"interesting_parent_ids":["GO:0070647","GO:0008150"],"is_obsolete":false,"name":"negative regulation of protein K48-linked ubiquitination","termid":"GO:0061944"}


id: GO:0110038
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of nematode male tail tip morphogenesis.","definition_xrefs":["PMID:28068334","GOC:rz"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of developmental process","termid":"GO:0051093"},{"relation_name":"is_a","term_name":"negative regulation of multicellular organismal process","termid":"GO:0051241"},{"relation_name":"is_a","term_name":"regulation of nematode male tail tip morphogenesis","termid":"GO:0110037"},{"relation_name":"negatively_regulates","term_name":"nematode male tail tip morphogenesis","termid":"GO:0045138"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of nematode male tail tip morphogenesis","termid":"GO:0110038"}


id: GO:0048852
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of the diencephalon are generated and organized. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex.","definition_xrefs":["GOC:cls","GOC:dph","GOC:dgh","GOC:jid","ISBN:0838580343"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure morphogenesis","termid":"GO:0009653"},{"relation_name":"part_of","term_name":"diencephalon development","termid":"GO:0021536"},{"relation_name":"part_of","term_name":"forebrain morphogenesis","termid":"GO:0048853"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"diencephalon morphogenesis","termid":"GO:0048852"}


id: PBO:0087667
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of the inner ring of the nuclear pore complex (NPC); contributes to NPC assembly and tethering of DNA to the nuclear periphery; both Nup170p and NUP157p are similar to human Nup155p; NUP157 has a paralog, NUP170, that arose from the whole genome duplication","termid":"PBO:0087667"}


id: PBO:0113019
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Benzil oxidoreductase with preference for NADPH; localizes to the cytoplasm; sequence similarity with short-chain dehydrogenase/reductases; putative paralog of IRC24","termid":"PBO:0113019"}


id: GO:1901750
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of leukotriene D4.","definition_xrefs":["GOC:TermGenie","GOC:yaf","UniPathway:UPA00880"],"direct_ancestors":[{"relation_name":"is_a","term_name":"leukotriene biosynthetic process","termid":"GO:0019370"},{"relation_name":"is_a","term_name":"amide biosynthetic process","termid":"GO:0043604"},{"relation_name":"is_a","term_name":"sulfur compound biosynthetic process","termid":"GO:0044272"},{"relation_name":"is_a","term_name":"fatty acid derivative biosynthetic process","termid":"GO:1901570"},{"relation_name":"is_a","term_name":"leukotriene D4 metabolic process","termid":"GO:1901748"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0006790"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006629","GO:0006790","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"leukotriene D4 biosynthetic process","synonyms":[{"name":"leukotriene D4 anabolism","type":"exact"},{"name":"leukotriene D4 biosynthesis","type":"exact"},{"name":"leukotriene D4 formation","type":"exact"},{"name":"leukotriene D4 synthesis","type":"exact"}],"termid":"GO:1901750"}


id: PBO:0059705
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-CO2 pseudogene 13","termid":"PBO:0059705"}


id: PBO:0000556
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADPH-dependent diflavin oxidoreductase, involved in iron-sulphur cluster assembly Tah18 (predicted)","termid":"PBO:0000556"}


id: PBO:0082792
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of the U1 snRNP complex required for pre-mRNA splicing; putative ortholog of human U1C protein, which is involved in formation of a complex between U1 snRNP and the pre-mRNA 5' splice site","termid":"PBO:0082792"}


id: PBO:0087913
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Transcription factor involved in phospholipid synthesis; required for derepression of inositol-choline-regulated genes involved in phospholipid synthesis; forms a complex, with Ino2p, that binds the inositol-choline-responsive element through a basic helix-loop-helix domain","termid":"PBO:0087913"}


id: PBO:0031324
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_hygromycin_B","termid":"PBO:0031324"}


id: PBO:0013780
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcription factor, zf-fungal binuclear cluster type Mca1 (predicted)","termid":"PBO:0013780"}


id: PBO:0055951
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leucine rich repeat containing 59","termid":"PBO:0055951"}


id: PBO:0059214
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MRN complex interacting protein","termid":"PBO:0059214"}


id: MONDO:0007524
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"The autosomal dominant form of the vascular type of Ehlers-Danlos syndrome. vEDS is almost always inherited in an autosomal dominant manner but rare examples of biallelic inheritance have been reported.","definition_xrefs":["MONDO:pr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant disease","termid":"MONDO:0000426"},{"relation_name":"is_a","term_name":"Ehlers-Danlos syndrome, vascular type","termid":"MONDO:0017314"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426"],"is_obsolete":false,"name":"autosomal dominant Ehlers-Danlos syndrome, vascular type","secondary_identifiers":["DOID:14756","MEDGEN:541286","UMLS:C0268339","OMIM:130050"],"synonyms":[{"name":"EDS 4","type":"broad"},{"name":"EDSVASC","type":"related"},{"name":"Ehlers-Danlos syndrome, Ecchymotic type","type":"related"},{"name":"Ehlers-Danlos syndrome, arterial type","type":"related"},{"name":"Ehlers-Danlos syndrome, sack-Barabas type","type":"related"},{"name":"Ehlers-Danlos syndrome, type IV, autosomal dominant","type":"exact"},{"name":"Ehlers-Danlos syndrome, vascular type","type":"broad"},{"name":"Ehlers-Danlos syndrome, vascular type, autosomal dominant","type":"exact"},{"name":"autosomal dominant Ehlers-Danlos syndrome, vascular type","type":"exact"},{"name":"autosomal dominant type IV Ehlers-Danlos syndrome","type":"related"}],"termid":"MONDO:0007524","xrefs":{"Monarch":{"xref_id":"0007524"}}}


id: PBO:0082767
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of the sorting and assembly machinery (SAM) complex; the SAM (or TOB) complex is located in the mitochondrial outer membrane; the complex binds precursors of beta-barrel proteins and facilitates their insertion into the outer membrane","termid":"PBO:0082767"}


id: PBO:0077964
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Ala (AGC) 17-1","termid":"PBO:0077964"}


id: GO:0160004
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a protein upon poly-ADP-ribosylation of the target protein.","definition_xrefs":["PMID:26673700"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ADP-D-ribose modification-dependent protein binding","termid":"GO:0160002"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005515","GO:0005488"],"is_obsolete":false,"name":"poly-ADP-D-ribose modification-dependent protein binding","termid":"GO:0160004"}


id: PBO:0065710
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pseudouridine synthase like 1","termid":"PBO:0065710"}


id: MOD:01357
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces two hydrogen atoms of an L-lysine residue containing common isotopes with two (13)C,3x(2)H labeled methyl groups to form a 2x(13)C,6x(2)H labeled dimethylated L-lysine.","definition_xrefs":["Unimod:510#K","PubMed:12686488","PubMed:16335955"],"direct_ancestors":[{"relation_name":"derives_from","term_name":"N6,N6-dimethyl-L-lysine","termid":"MOD:00084"},{"relation_name":"is_a","term_name":"modified L-lysine residue","termid":"MOD:00912"},{"relation_name":"is_a","term_name":"2x(13)C,4x(2)H labeled dimethylated residue","termid":"MOD:00927"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2x(13)C,4x(2)H labeled dimethylated L-lysine","synonyms":[{"name":"DiMethyl-C13HD2","type":"related"},{"name":"Dimethyl:2H(4)13C(2)","type":"related"}],"termid":"MOD:01357"}


id: GO:0030562
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Specifies the site of 2'-O-ribose methylation in an rRNA molecule by base pairing with a short sequence around the target residue.","definition_xrefs":["PMID:12457565","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"rRNA modification guide activity","termid":"GO:0030556"},{"relation_name":"is_a","term_name":"RNA 2'-O-ribose methylation guide activity","termid":"GO:0030561"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003723"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005488","GO:0003723"],"is_obsolete":false,"name":"rRNA 2'-O-ribose methylation guide activity","termid":"GO:0030562"}


id: MONDO:0023164
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Pericarditis that is caused by an infection with a viral agent.","definition_xrefs":["NCIT:C128405"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pericarditis","termid":"MONDO:0005904"},{"relation_name":"is_a","term_name":"primary viral infectious disease","termid":"MONDO:0100329"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"viral pericarditis","secondary_identifiers":["icd11.foundation:624707101","UMLS:C0276139","MEDGEN:547113","ICD10CM:B33.23","SCTID:70189005"],"synonyms":[{"name":"Viral Pericarditis","type":"related"},{"name":"Viral pericarditis","type":"related"},{"name":"viral pericarditis","type":"exact"}],"termid":"MONDO:0023164","xrefs":{"Monarch":{"xref_id":"0023164"}}}


id: GO:0060206
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The progression of physiological phases, occurring in the endometrium during the estrous cycle that recur at regular intervals during the reproductive years. The estrous cycle is an ovulation cycle where the endometrium is resorbed if pregnancy does not occur.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"biological phase","termid":"GO:0044848"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"estrous cycle phase","termid":"GO:0060206"}


id: PBO:0054803
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2216","termid":"PBO:0054803"}


id: GO:0010888
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.","definition_xrefs":["GOC:BHF","GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of lipid storage","termid":"GO:0010883"},{"relation_name":"is_a","term_name":"negative regulation of cellular process","termid":"GO:0048523"},{"relation_name":"is_a","term_name":"negative regulation of lipid localization","termid":"GO:1905953"},{"relation_name":"negatively_regulates","term_name":"lipid storage","termid":"GO:0019915"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of lipid storage","termid":"GO:0010888"}


id: FYPO:0002717
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which vacuole fusion is normal (i.e. indistinguishable from wild type) during a cellular response to a hypotonic environment.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal vacuole fusion during vegetative growth","termid":"FYPO:0002716"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0001312","FYPO:0000002","FYPO:0000257"],"is_obsolete":false,"name":"normal vacuole fusion during cellular hypotonic response","synonyms":[{"name":"normal homotypic vacuole fusion during cellular hypotonic response","type":"exact"},{"name":"normal vacuole fusion during cellular hypotonic response during mitotic cell cycle","type":"related"},{"name":"normal vacuole fusion during cellular hypotonic response during vegetative growth","type":"exact"},{"name":"normal vacuole fusion during hypotonic stress","type":"exact"},{"name":"normal vacuole fusion, non-autophagic, during cellular hypotonic response","type":"exact"}],"termid":"FYPO:0002717"}


id: PBO:0067715
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal 13","termid":"PBO:0067715"}


id: GO:1901971
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of DNA-5-methylcytosine glycosylase activity.","definition_xrefs":["GOC:TermGenie","PMID:23316050"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of DNA-5-methylcytosine glycosylase activity (obsolete GO:1901971)","termid":"GO:1901971"}


id: FYPO:0005602
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the amount of RNA derived from subtelomeric heterochromatin forming regions is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected.","definition_xrefs":["PMID:25356590","PMID:27183912"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal RNA level during vegetative growth","termid":"FYPO:0001317"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001312","FYPO:0000002","FYPO:0001320","FYPO:0000257"],"is_obsolete":false,"name":"normal subtelomeric heterochromatin RNA level","synonyms":[{"name":"normal subtelomere-derived RNA level","type":"exact"},{"name":"normal subtelomere-derived RNA level during vegetative growth","type":"exact"},{"name":"normal subtelomere-derived RNA transcript level","type":"exact"}],"termid":"FYPO:0005602"}


id: GO:0004152
data:
  {"annotated_genes":["SJAG_00197"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[57332],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0106430"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: (S)-dihydroorotate + A = AH(2) + orotate.","definition_xrefs":["RHEA:18073"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-CH group of donors","termid":"GO:0016627"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00197":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016491","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"dihydroorotate dehydrogenase activity","references_by_uniquename":{"GO_REF:0000003":null},"secondary_identifiers":["MetaCyc:DIHYDROOROTATE-DEHYDROGENASE-RXN","Reactome:R-HSA-73569","KEGG_REACTION:R01868"],"termid":"GO:0004152","terms_by_termid":{"GO:0106430":null}}


id: GO:0003388
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of a neuron over time, that contributes to the development of the amphid sensory organ.","definition_xrefs":["GOC:dph","GOC:ascb_2009","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neuron development","termid":"GO:0048666"},{"relation_name":"part_of","term_name":"neuron differentiation involved in amphid sensory organ development","termid":"GO:0003387"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"neuron development involved in amphid sensory organ development","termid":"GO:0003388"}


id: GO:0047533
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2,5-dioxopentanoate + NADP+ + H2O = 2-oxoglutarate + NADPH + H+.","definition_xrefs":["MetaCyc:25-DIOXOVALERATE-DEHYDROGENASE-RXN","EC:1.2.1.26"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor","termid":"GO:0016620"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"2,5-dioxovalerate dehydrogenase (NADP+) activity","secondary_identifiers":["RHEA:11296"],"synonyms":[{"name":"2,5-dioxopentanoate:NADP+ 5-oxidoreductase activity","type":"related"},{"name":"2-oxoglutarate semialdehyde dehydrogenase activity","type":"related"},{"name":"alpha-ketoglutaric semialdehyde dehydrogenase activity","type":"related"}],"termid":"GO:0047533"}


id: PBO:0027744
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_protein_localization_to_nucleus_during_glucose_starvation","termid":"PBO:0027744"}


id: PBO:0071674
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L37 pseudogene 6","termid":"PBO:0071674"}


id: PBO:0001499
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proteasome regulatory particle, gankyrin (predicted)","termid":"PBO:0001499"}


id: PBO:0048305
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glyceraldehyde-3-phosphate dehydrogenase pseudogene 15","termid":"PBO:0048305"}


id: PBO:0036327
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"inosine-containing RNA endoribonuclease (predicted)","termid":"PBO:0036327"}


id: RO:0002471
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","direct_ancestors":[{"relation_name":"is_a","term_name":"trophically_interacts_with","termid":"RO:0002438"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"is_eaten_by","termid":"RO:0002471"}


id: MONDO:0020531
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A genetic disorder characterized by deficiency of the enzyme long-chain acyl-coenzyme A dehydrogenase that metabolizes long-chain fatty acids. Signs and symptoms appear in infancy or childhood and may be triggered during fasting, illness or exercise. They include hypoglycemia, muscle weakness and lethargy.","definition_xrefs":["NCIT:C84537"],"direct_ancestors":[{"relation_name":"is_a","term_name":"disorder of fatty acid oxidation and ketogenesis","termid":"MONDO:0017713"},{"relation_name":"is_a","term_name":"familial hypertrophic cardiomyopathy","termid":"MONDO:0024573"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0005267"},{"rel_name":"is_a","termid":"MONDO:0002525"}],"interesting_parent_ids":["MONDO:0002525","MONDO:0005066","MONDO:0005267"],"is_obsolete":false,"name":"long chain acyl-CoA dehydrogenase deficiency","secondary_identifiers":["icd11.foundation:692829041","Orphanet:99900","MEDGEN:65087","UMLS:C0220711","MESH:C535690","SCTID:237996001"],"synonyms":[{"name":"ACADL deficiency","type":"related"},{"name":"LCAD","type":"exact"},{"name":"LCAD deficiency","type":"related"},{"name":"acyl-CoA dehydrogenase, long-chain deficiency","type":"exact"},{"name":"inborn error of long-chain-acyl-CoA dehydrogenase activity","type":"exact"},{"name":"inborn long-chain-acyl-CoA dehydrogenase activity disorder","type":"exact"},{"name":"long chain acyl-CoA dehydrogenase deficiency","type":"exact"},{"name":"long-chain acyl-CoA dehydrogenase deficiency","type":"exact"},{"name":"long-chain acyl-Coenzyme A dehydrogenase deficiency","type":"exact"},{"name":"rare inborn error of long-chain-acyl-CoA dehydrogenase activity","type":"exact"}],"termid":"MONDO:0020531","xrefs":{"Monarch":{"xref_id":"0020531"}}}


id: GO:0021591
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the brain ventricular system over time, from its formation to the mature structure. The brain ventricular system consists of four communicating cavities within the brain that are continuous with the central canal of the spinal cord. These cavities include two lateral ventricles, the third ventricle and the fourth ventricle. Cerebrospinal fluid fills the ventricles and is produced by the choroid plexus.","definition_xrefs":["GO_REF:0000021","GOC:dph","GOC:jid","GOC:cls","GOC:dgh","ISBN:0838580343"],"direct_ancestors":[{"relation_name":"is_a","term_name":"system development","termid":"GO:0048731"},{"relation_name":"part_of","term_name":"brain development","termid":"GO:0007420"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"ventricular system development","termid":"GO:0021591"}


id: PBO:0087030
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ribosomal 60S subunit protein L14B; homologous to mammalian ribosomal protein L14, no bacterial homolog; RPL14B has a paralog, RPL14A, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress","termid":"PBO:0087030"}


id: PBO:0116587
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FOXN3 antisense RNA 3","termid":"PBO:0116587"}


id: PBO:0077411
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein 147","termid":"PBO:0077411"}


id: PBO:0089560
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ER protein translocation subcomplex subunit Sec66","termid":"PBO:0089560"}


id: PBO:0084974
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NAD(+)-dependent histone deacetylase; essential subunit of the Sum1p/Rfm1p/Hst1p complex required for ORC-dependent silencing and meiotic repression; non-essential subunit of the Set3C deacetylase complex; involved in telomere maintenance; HST1 has a paralog, SIR2, that arose from the whole genome duplication","termid":"PBO:0084974"}


id: FYPO:0003552
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which the occurrence of an RNA catabolic process is decreased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"has_output","term_name":"increased RNA level","termid":"FYPO:0001890"},{"relation_name":"is_a","term_name":"abnormal RNA catabolic process","termid":"FYPO:0003551"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000294"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000294","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"decreased RNA catabolic process","synonyms":[{"name":"decreased RNA breakdown","type":"exact"},{"name":"decreased RNA catabolism","type":"exact"},{"name":"decreased RNA degradation","type":"exact"},{"name":"reduced RNA catabolic process","type":"exact"}],"termid":"FYPO:0003552"}


id: MONDO:0014666
data:
  {"annotated_genes":["SJAG_01444"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86916],"is_not":false,"summary":null,"term":"MONDO:0014666"}]},"cv_name":"mondo","definition":"Any leukodystrophy in which the cause of the disease is a mutation in the POLR1C gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"POLR1C-related disorder","termid":"MONDO:0700278"},{"relation_name":"is_a","term_name":"POLR3-related leukodystrophy","termid":"MONDO:0700282"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01444":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"hypomyelinating leukodystrophy 11","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:897960","OMIM:616494","UMLS:C4225305","DOID:0060792","GARD:18088"],"synonyms":[{"name":"HLD11","type":"exact"},{"name":"POLR1C leukodystrophy","type":"exact"},{"name":"hypomyelinating leukodystrophy type 11","type":"exact"},{"name":"leukodystrophy caused by mutation in POLR1C","type":"exact"},{"name":"leukodystrophy, hypomyelinating, 11","type":"related"},{"name":"leukodystrophy, hypomyelinating, type 11","type":"exact"}],"termid":"MONDO:0014666","terms_by_termid":{"MONDO:0014666":null},"xrefs":{"Monarch":{"xref_id":"0014666"}}}


id: GO:0031679
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: NADH + H+ + plastoquinone = NAD+ + plastoquinol.","definition_xrefs":["EC:1.6.99.6","GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete NADH dehydrogenase (plastoquinone) activity (obsolete GO:0031679)","synonyms":[{"name":"NADH:plastoquinone reductase activity","type":"exact"}],"termid":"GO:0031679"}


id: FYPO:0007122
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of assembly of one or more mitochondrial respiratory chain complexes is decreased.","definition_xrefs":["PMID:31350787","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein-containing complex assembly","termid":"FYPO:0000447"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0005447","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"decreased mitochondrial respiratory chain complex assembly","synonyms":[{"name":"decreased mitochondrial respiratory chain complex assembly during mitotic cell cycle","type":"related"},{"name":"decreased mitochondrial respiratory chain complex assembly during vegetative growth","type":"exact"},{"name":"decreased mitochondrial respiratory complex assembly","type":"exact"},{"name":"reduced mitochondrial respiratory chain complex assembly","type":"exact"}],"termid":"FYPO:0007122"}


id: PBO:0083368
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps uncharacterized ORF YDL086W; identified by gene-trapping, microarray expression analysis, and genome-wide homology searching","termid":"PBO:0083368"}


id: PBO:0053145
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lactate dehydrogenase A pseudogene 1","termid":"PBO:0053145"}


id: GO:0032229
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of synaptic transmission, GABAergic","termid":"GO:0032228"},{"relation_name":"is_a","term_name":"negative regulation of synaptic transmission","termid":"GO:0050805"},{"relation_name":"negatively_regulates","term_name":"synaptic transmission, GABAergic","termid":"GO:0051932"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"negative regulation of synaptic transmission, GABAergic","synonyms":[{"name":"down regulation of synaptic transmission, GABAergic","type":"exact"},{"name":"down-regulation of synaptic transmission, GABAergic","type":"exact"},{"name":"downregulation of synaptic transmission, GABAergic","type":"exact"},{"name":"inhibition of synaptic transmission, GABAergic","type":"narrow"}],"termid":"GO:0032229"}


id: GO:0042185
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of m-xylene, 1,3-dimethylbenzene, a colorless, liquid aromatic hydrocarbon.","definition_xrefs":["GOC:jl","GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"m-xylene metabolic process","termid":"GO:0018949"},{"relation_name":"is_a","term_name":"xylene catabolic process","termid":"GO:0042184"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"m-xylene catabolic process","secondary_identifiers":["MetaCyc:PWY-142"],"synonyms":[{"name":"m-xylene breakdown","type":"exact"},{"name":"m-xylene catabolism","type":"exact"},{"name":"m-xylene degradation","type":"exact"},{"name":"meta-xylene catabolic process","type":"exact"},{"name":"meta-xylene catabolism","type":"exact"}],"termid":"GO:0042185"}


id: PBO:0001922
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"manganese superoxide dismutase (predicted)","termid":"PBO:0001922"}


id: GO:0045306
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Inhibits the establishment of competence for transformation.","definition_xrefs":["GOC:mlg"],"gene_count":0,"genotype_count":0,"name":"obsolete inhibitor of the establishment of competence for transformation activity (obsolete GO:0045306)","synonyms":[{"name":"inhibitor of the establishment of competence for transformation activity","type":"exact"}],"termid":"GO:0045306"}


id: GO:0090107
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle.","definition_xrefs":["GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of protein-containing complex assembly","termid":"GO:0043254"},{"relation_name":"is_a","term_name":"regulation of multicellular organismal process","termid":"GO:0051239"},{"relation_name":"regulates","term_name":"high-density lipoprotein particle assembly","termid":"GO:0034380"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044085"},{"rel_name":"regulates","termid":"GO:0065003"}],"interesting_parent_ids":["GO:0008150","GO:0065003","GO:0044085"],"is_obsolete":false,"name":"regulation of high-density lipoprotein particle assembly","termid":"GO:0090107"}


id: GO:0102246
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: aminodeoxyfutalosinate + H2O = dehypoxanthine futalosine + adenine.","definition_xrefs":["EC:3.2.2.30","GOC:pz"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, hydrolyzing N-glycosyl compounds","termid":"GO:0016799"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016798"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"}],"interesting_parent_ids":["GO:0016787","GO:0016798","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"6-amino-6-deoxyfutalosine hydrolase activity","secondary_identifiers":["MetaCyc:RXN-12346","RHEA:33079"],"termid":"GO:0102246"}


id: GO:1900849
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of pseurotin A biosynthetic process.","definition_xrefs":["GOC:TermGenie","GOC:di"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of biosynthetic process","termid":"GO:0009889"},{"relation_name":"is_a","term_name":"regulation of amide metabolic process","termid":"GO:0034248"},{"relation_name":"is_a","term_name":"regulation of small molecule metabolic process","termid":"GO:0062012"},{"relation_name":"regulates","term_name":"pseurotin A biosynthetic process","termid":"GO:1900790"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0044281"],"is_obsolete":false,"name":"regulation of pseurotin A biosynthetic process","synonyms":[{"name":"regulation of Pseurotin anabolism","type":"related"},{"name":"regulation of Pseurotin biosynthesis","type":"related"},{"name":"regulation of Pseurotin biosynthetic process","type":"related"},{"name":"regulation of Pseurotin formation","type":"related"},{"name":"regulation of Pseurotin synthesis","type":"related"},{"name":"regulation of pseurotin A anabolism","type":"exact"},{"name":"regulation of pseurotin A biosynthesis","type":"exact"},{"name":"regulation of pseurotin A formation","type":"exact"},{"name":"regulation of pseurotin A synthesis","type":"exact"}],"termid":"GO:1900849"}


id: PBO:0060227
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"matrix remodeling associated 8","termid":"PBO:0060227"}


id: PBO:0001043
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Pop-Interacting Protein","termid":"PBO:0001043"}


id: GO:0038163
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals initiated by thrombopoietin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.","definition_xrefs":["GOC:nhn","GOC:signaling","PMID:19630807"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chemokine-mediated signaling pathway","termid":"GO:0070098"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"thrombopoietin-mediated signaling pathway","synonyms":[{"name":"THPO signaling pathway","type":"exact"},{"name":"THPO/MPL signaling pathway","type":"exact"},{"name":"thrombopoietin receptor signaling pathway","type":"exact"}],"termid":"GO:0038163"}


id: GO:0003068
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The regulation of blood pressure mediated by acetylcholine signaling. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter.","definition_xrefs":["GOC:rl","GOC:mtg_cardio"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of systemic arterial blood pressure by neurotransmitter","termid":"GO:0003070"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of systemic arterial blood pressure by acetylcholine","synonyms":[{"name":"blood pressure regulation by acetylcholine","type":"exact"}],"termid":"GO:0003068"}


id: PBO:0054762
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2174","termid":"PBO:0054762"}


id: PR:O13901
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An ethanolaminephosphotransferase 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO00472"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized CDP-alcohol phosphatidyltransferase class-I family protein C22A12.10 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC22A12.10","secondary_identifiers":["UniProtKB:O13901"],"synonyms":[{"name":"Spom972h-EPT1","type":"exact"}],"termid":"PR:O13901"}


id: FYPO:0003933
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of an exonucleolytic RNA catabolic process that proceeds in the 5' to 3' direction to degrade mRNA encoded in the nucleus is decreased.","definition_xrefs":["GO:0034428","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular metabolism phenotype during vegetative growth","termid":"FYPO:0001348"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"decreased nuclear 5'-3' exonucleolytic mRNA catabolic process","synonyms":[{"name":"decreased 5'-3' exonucleolytic nuclear-transcribed mRNA catabolic process","type":"exact"},{"name":"decreased nuclear 5'-3' exonucleolytic mRNA catabolic process during mitotic cell cycle","type":"related"},{"name":"decreased nuclear 5'-3' exonucleolytic mRNA catabolic process during vegetative growth","type":"exact"},{"name":"decreased nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3'","type":"exact"},{"name":"reduced nuclear 5'-3' exonucleolytic mRNA catabolic process","type":"exact"}],"termid":"FYPO:0003933"}


id: MONDO:0012728
data:
  {"annotated_genes":["SJAG_01012","SJAG_00409"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86822,86823],"is_not":false,"summary":null,"term":"MONDO:0012728"}]},"cv_name":"mondo","definition":"Any Brugada syndrome in which the cause of the disease is a mutation in the GPD1L gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Brugada syndrome","termid":"MONDO:0015263"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00409":null,"SJAG_01012":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"Brugada syndrome 2","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C2673193","DOID:0110219","OMIM:611777","MESH:C567087","MEDGEN:382031","GARD:15526"],"synonyms":[{"name":"BRGDA2","type":"exact"},{"name":"Brugada syndrome 2","type":"exact"},{"name":"Brugada syndrome caused by mutation in GPD1L","type":"exact"},{"name":"Brugada syndrome type 2","type":"exact"},{"name":"GPD1L Brugada syndrome","type":"exact"}],"termid":"MONDO:0012728","terms_by_termid":{"MONDO:0012728":null},"xrefs":{"Monarch":{"xref_id":"0012728"}}}


id: PBO:0015223
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glucosidase II alpha subunit Gls2","termid":"PBO:0015223"}


id: PBO:0051109
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin heavy variable 1-46","termid":"PBO:0051109"}


id: PBO:0065541
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PTENP1 antisense RNA","termid":"PBO:0065541"}


id: PBO:0084978
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADH-dependent aldehyde reductase; involved in detoxification of furfural; expression is up-regulated in the presence of furfural and 5-hydroxymethylfurfural, which are compounds generated during lignocellulosic biomass pre-treatment; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and nucleus; protein abundance increases in response to DNA replication stress","termid":"PBO:0084978"}


id: SO:0000960
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"Structural unit composed of a self-replicating, single-stranded, circular DNA molecule.","definition_xrefs":["SO:ma"],"direct_ancestors":[{"relation_name":"has_quality","term_name":"circular","termid":"SO:0000988"},{"relation_name":"is_a","term_name":"single_stranded_DNA_chromosome","termid":"SO:0000956"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"circular_single_stranded_DNA_chromosome","synonyms":[{"name":"circular single stranded DNA chromosome","type":"exact"}],"termid":"SO:0000960"}


id: MONDO:1011773
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"musculoskeletal system disorder, non-human animal","termid":"MONDO:1011335"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"degenerative suspensory ligament desmitis, non-human animal","secondary_identifiers":["OMIA:002086"],"termid":"MONDO:1011773","xrefs":{"Monarch":{"xref_id":"1011773"}}}


id: PBO:0087547
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of RNA polymerase III transcription initiation factor complex; one of six subunits of RNA polymerase III transcription initiation factor complex (TFIIIC); part of TFIIIC TauB domain that binds BoxB promoter sites of tRNA and other genes; linker between TauB and TauA domains; human homolog is TFIIIC-90","termid":"PBO:0087547"}


id: PBO:0078937
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Arg (anticodon CCT) 5-1","termid":"PBO:0078937"}


id: GO:1901517
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of aspyridone A.","definition_xrefs":["GOC:di","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polyketide catabolic process","termid":"GO:0030640"},{"relation_name":"is_a","term_name":"pyridine-containing compound catabolic process","termid":"GO:0072526"},{"relation_name":"is_a","term_name":"aspyridone A metabolic process","termid":"GO:1901516"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0019748"}],"interesting_parent_ids":["GO:0008150","GO:0019748"],"is_obsolete":false,"name":"aspyridone A catabolic process","synonyms":[{"name":"aspyridone A breakdown","type":"exact"},{"name":"aspyridone A catabolism","type":"exact"},{"name":"aspyridone A degradation","type":"exact"}],"termid":"GO:1901517"}


id: PBO:0045455
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"downregulated RNA in cancer, inhibitor of cell invasion and migration","termid":"PBO:0045455"}


id: GO:0086012
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.","definition_xrefs":["GOC:mtg_cardiac_conduct_nov11","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"membrane depolarization during action potential","termid":"GO:0086010"},{"relation_name":"part_of","term_name":"cardiac muscle cell action potential","termid":"GO:0086001"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"membrane depolarization during cardiac muscle cell action potential","termid":"GO:0086012"}


id: GO:0031266
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex formed upon binding of TRAIL to its ligand. The complex includes FADD/Mort1 and procaspase-8 addition to the ligand-bound receptor.","definition_xrefs":["PMID:12628743","PMID:12655293"],"direct_ancestors":[{"relation_name":"is_a","term_name":"death-inducing signaling complex","termid":"GO:0031264"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005886"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0005886","GO:0032991"],"is_obsolete":false,"name":"TRAIL death-inducing signaling complex","synonyms":[{"name":"TRAIL DISC","type":"exact"},{"name":"TRAIL death-inducing signalling complex","type":"exact"}],"termid":"GO:0031266"}


id: GO:0044854
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The aggregation, arrangement and bonding together of a set of components to form a plasma membrane raft.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"membrane raft assembly","termid":"GO:0001765"},{"relation_name":"is_a","term_name":"plasma membrane raft organization","termid":"GO:0044857"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"part_of","termid":"GO:0061024"},{"rel_name":"is_a","termid":"GO:0061024"}],"interesting_parent_ids":["GO:0008150","GO:0044085","GO:0061024"],"is_obsolete":false,"name":"plasma membrane raft assembly","termid":"GO:0044854"}


id: PBO:0062420
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 7 subfamily E member 62 pseudogene","termid":"PBO:0062420"}


id: GO:0033633
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate, or extent of cell-cell adhesion mediated by integrin.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cell-cell adhesion","termid":"GO:0022408"},{"relation_name":"is_a","term_name":"negative regulation of cell adhesion mediated by integrin","termid":"GO:0033629"},{"relation_name":"is_a","term_name":"regulation of cell-cell adhesion mediated by integrin","termid":"GO:0033632"},{"relation_name":"negatively_regulates","term_name":"cell-cell adhesion mediated by integrin","termid":"GO:0033631"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0007155"},{"rel_name":"regulates","termid":"GO:0007155"}],"interesting_parent_ids":["GO:0007155","GO:0008150"],"is_obsolete":false,"name":"negative regulation of cell-cell adhesion mediated by integrin","synonyms":[{"name":"negative regulation of cell-cell adhesion mediated by integrin complex","type":"exact"}],"termid":"GO:0033633"}


id: GO:0030239
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Formation of myofibrils, the repeating units of striated muscle.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular component assembly involved in morphogenesis","termid":"GO:0010927"},{"relation_name":"is_a","term_name":"actomyosin structure organization","termid":"GO:0031032"},{"relation_name":"is_a","term_name":"supramolecular fiber organization","termid":"GO:0097435"},{"relation_name":"is_a","term_name":"membraneless organelle assembly","termid":"GO:0140694"},{"relation_name":"part_of","term_name":"striated muscle cell development","termid":"GO:0055002"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0007010"},{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0030036"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0007010","GO:0030036","GO:0008150","GO:0044085"],"is_obsolete":false,"name":"myofibril assembly","termid":"GO:0030239"}


id: FYPO:0000961
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing sorbitol.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal vegetative cell population growth","termid":"FYPO:0001357"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000139","FYPO:0002057","FYPO:0000003","FYPO:0000257","FYPO:0002058","FYPO:0002060"],"is_obsolete":false,"name":"normal growth on sorbitol","synonyms":[{"name":"normal cell population growth in presence of sorbitol","type":"exact"},{"name":"normal cell population growth on glucitol","type":"exact"},{"name":"normal cell population growth on sorbitol","type":"exact"},{"name":"normal cellular response to sorbitol","type":"related"},{"name":"normal vegetative cell population growth on sorbitol","type":"exact"}],"termid":"FYPO:0000961"}


id: MONDO:0025370
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. Tumors or cancer of the urogenital system in either the male or the female.","definition_xrefs":["MESH:D014565"],"gene_count":0,"genotype_count":0,"name":"obsolete urogenital neoplasm (obsolete MONDO:0025370)","synonyms":[{"name":"genito-urinary neoplasm","type":"related"},{"name":"genito-urinary neoplasms","type":"related"},{"name":"genitourinary neoplasm","type":"related"},{"name":"genitourinary neoplasms","type":"related"},{"name":"genitourinary system neoplasm","type":"exact"},{"name":"genitourinary system tumor","type":"exact"},{"name":"neoplasm of genitourinary system","type":"exact"},{"name":"neoplasm, genito-urinary","type":"related"},{"name":"neoplasm, genitourinary","type":"related"},{"name":"neoplasm, urogenital","type":"related"},{"name":"neoplasms, genito-urinary","type":"related"},{"name":"neoplasms, genitourinary","type":"related"},{"name":"neoplasms, urogenital","type":"related"},{"name":"tumor of genitourinary system","type":"exact"},{"name":"urogenital neoplasm","type":"exact"}],"termid":"MONDO:0025370","xrefs":{"Monarch":{"xref_id":"0025370"}}}


id: GO:0034177
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate, or extent of toll-like receptor 12 signaling pathway.","definition_xrefs":["GOC:add","PMID:16551253","PMID:17328678"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of toll-like receptor 12 signaling pathway","termid":"GO:0034175"},{"relation_name":"is_a","term_name":"positive regulation of pattern recognition receptor signaling pathway","termid":"GO:0062208"},{"relation_name":"is_a","term_name":"positive regulation of intracellular signal transduction","termid":"GO:1902533"},{"relation_name":"positively_regulates","term_name":"toll-like receptor 12 signaling pathway","termid":"GO:0034174"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"positive regulation of toll-like receptor 12 signaling pathway","synonyms":[{"name":"positive regulation of TLR12 signaling pathway","type":"exact"},{"name":"positive regulation of toll-like receptor 12 signalling pathway","type":"exact"}],"termid":"GO:0034177"}


id: PBO:0030658
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_Man9GlcNAc_level","termid":"PBO:0030658"}


id: MOD:00932
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"modification from Unimod Isotopic label","definition_xrefs":["Unimod:499","PubMed:11821862"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified L-cysteine residue","termid":"MOD:00905"},{"relation_name":"is_a","term_name":"isotope tagged reagent derivatized residue","termid":"MOD:01426"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"}],"interesting_parent_ids":["MOD:00905"],"is_obsolete":false,"name":"IDBEST tag for quantitation","synonyms":[{"name":"Heavy IDBEST tag for quantitation","type":"related"},{"name":"IGBP:13C(2)","type":"related"}],"termid":"MOD:00932"}


id: PBO:0089260
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vacuolar membrane hydrolase, implicted in protein catabolism or lipid metabolism","termid":"PBO:0089260"}


id: GO:0140952
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-lysyl27-[histone H3] + 2 S-adenosyl-L-methionine = 2 H+ + N6,N6-dimethyl-L-lysyl27-[histone H3] + 2 S-adenosyl-L-homocysteine. This reaction is the successive addition of two methyl groups to the unmethylated lysine residue at position 27 of histone H3, producing histone H3K27me2.","definition_xrefs":["RHEA:64452"],"direct_ancestors":[{"relation_name":"is_a","term_name":"histone H3K27 methyltransferase activity","termid":"GO:0046976"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008276"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016740","GO:0003674","GO:0003824","GO:0140096","GO:0008276","GO:0016741"],"is_obsolete":false,"name":"histone H3K27 dimethyltransferase activity","secondary_identifiers":["EC:2.1.1.371"],"synonyms":[{"name":"histone H3-K27 dimethylase activity","type":"exact"},{"name":"histone H3-K27 dimethylation","type":"broad"},{"name":"histone H3K27 dimethylase activity","type":"exact"},{"name":"histone H3K27 dimethylation","type":"broad"},{"name":"histone H3K27 mono/dimethylase activity","type":"exact"},{"name":"histone lysine N-dimethyltransferase activity (H3-K27 specific)","type":"exact"}],"termid":"GO:0140952"}


id: PBO:0065717
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Prader Willi/Angelman region RNA 1","termid":"PBO:0065717"}


id: MONDO:0017556
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Madelung deformity","termid":"MONDO:0018154"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"Madelung deformity, unilateral","secondary_identifiers":["icd11.foundation:1964514438","Orphanet:295221"],"termid":"MONDO:0017556","xrefs":{"Monarch":{"xref_id":"0017556"}}}


id: PR:000050476
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein kinase wis1 (Schizosaccharomyces pombe) that has not been phosphorylated on residues equivalent to Ser-469 and Thr-473 of the amino acid sequence represented by UniProtKB:P33886. Example: UniProtKB:P33886, Ser-469/Thr-473, PR:000026291.","definition_xrefs":["PMID:12181336","PomBase:VW","PRO:DAN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein kinase wis1 (Schizosaccharomyces pombe)","termid":"PR:000050474"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"wis1/UnPhos:(S469,T473)","pombase_gene_id":"SPBC409.07c","synonyms":[{"name":"PomBase_original_PRO_term_name: protein kinase wis1 unphosphorylated 1 (Schizosaccharomyces pombe)","type":"exact"},{"name":"Spom-wis1/UnPhos:1","type":"exact"},{"name":"UniProtKB:P33886, Ser-469/Thr-473, PR:000026291","type":"narrow"},{"name":"wis1/UnPhos:(S469,T473)","type":"exact"}],"termid":"PR:000050476"}


id: GO:0140816
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the transfer of ADP-ribose groups to the serine-6 or an equivalent residue of the N-terminal tail of histone H2B.","definition_xrefs":["PMID:34874266"],"direct_ancestors":[{"relation_name":"is_a","term_name":"NAD+-protein-serine ADP-ribosyltransferase activity","termid":"GO:0140805"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016757"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0003674","GO:0140096","GO:0016757","GO:0016740","GO:0003824"],"is_obsolete":false,"name":"NAD+-histone H2BS6 serine ADP-ribosyltransferase activity","synonyms":[{"name":"NAD+-histone H2B-S6 serine ADP-ribosyltransferase activity","type":"exact"},{"name":"NAD+-histone-serine ADP-ribosyltransferase activity (H2B-S6 specific)","type":"exact"}],"termid":"GO:0140816"}


id: PBO:0081788
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 716","termid":"PBO:0081788"}


id: PBO:0110470
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cilia and flagella associated protein 263","termid":"PBO:0110470"}


id: MONDO:0018568
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete COG2-CDG (obsolete MONDO:0018568)","termid":"MONDO:0018568","xrefs":{"Monarch":{"xref_id":"0018568"}}}


id: PBO:0005800
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"AMpK subunit","termid":"PBO:0005800"}


id: PBO:0112594
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial oxidoreductase for ubiquinone biosynthesis","termid":"PBO:0112594"}


id: FYPO:0000568
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which mating projection assembly is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal cellular component assembly","termid":"FYPO:0000336"},{"relation_name":"is_a","term_name":"abnormal shmoo directionality","termid":"FYPO:0005791"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000301"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000301","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"abnormal shmoo formation","synonyms":[{"name":"abnormal conjugation tube formation","type":"exact"},{"name":"abnormal mating projection assembly","type":"exact"},{"name":"abnormal mating projection formation","type":"exact"},{"name":"abnormal shmoo assembly","type":"exact"},{"name":"shmoo formation: abnormal","type":"related"}],"termid":"FYPO:0000568"}


id: GO:1900841
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of helvolic acid biosynthetic process.","definition_xrefs":["GOC:TermGenie","GOC:di"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of steroid biosynthetic process","termid":"GO:0010894"},{"relation_name":"is_a","term_name":"negative regulation of small molecule metabolic process","termid":"GO:0062014"},{"relation_name":"is_a","term_name":"negative regulation of secondary metabolite biosynthetic process","termid":"GO:1900377"},{"relation_name":"is_a","term_name":"regulation of helvolic acid biosynthetic process","termid":"GO:1900840"},{"relation_name":"negatively_regulates","term_name":"helvolic acid biosynthetic process","termid":"GO:1900812"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0019748"},{"rel_name":"regulates","termid":"GO:0006629"},{"rel_name":"negatively_regulates","termid":"GO:0044281"},{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0019748"},{"rel_name":"negatively_regulates","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0044281","GO:0006629","GO:0008150","GO:0019748"],"is_obsolete":false,"name":"negative regulation of helvolic acid biosynthetic process","synonyms":[{"name":"down regulation of helvolic acid biosynthetic process","type":"exact"},{"name":"down-regulation of helvolic acid biosynthetic process","type":"exact"},{"name":"downregulation of helvolic acid biosynthetic process","type":"exact"}],"termid":"GO:1900841"}


id: PBO:0082983
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cytosine deaminase; zinc metalloenzyme that catalyzes the hydrolytic deamination of cytosine to uracil; of biomedical interest because it also catalyzes the deamination of 5-fluorocytosine (5FC) to form anticancer drug 5-fluorouracil (5FU)","termid":"PBO:0082983"}


id: PBO:0016881
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Schizosaccharomyces pombe specific protein","termid":"PBO:0016881"}


id: MONDO:0003148
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete SM-AHNMD (obsolete MONDO:0003148)","termid":"MONDO:0003148","xrefs":{"Monarch":{"xref_id":"0003148"}}}


id: PBO:0080619
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WD repeat domain 55","termid":"PBO:0080619"}


id: PBO:0045821
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"eukaryotic translation elongation factor 1 alpha 1 pseudogene 11","termid":"PBO:0045821"}


id: PBO:0030337
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_chromatin_organization_during_nitrogen_starvation","termid":"PBO:0030337"}


id: GO:0045709
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination in an adult organism.","definition_xrefs":["GOC:tb","GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of salivary gland boundary specification","termid":"GO:0045705"},{"relation_name":"is_a","term_name":"regulation of adult salivary gland boundary specification","termid":"GO:0045707"},{"relation_name":"negatively_regulates","term_name":"adult salivary gland boundary specification","termid":"GO:0007434"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of adult salivary gland boundary specification","synonyms":[{"name":"down regulation of adult salivary gland determination","type":"exact"},{"name":"down-regulation of adult salivary gland determination","type":"exact"},{"name":"downregulation of adult salivary gland determination","type":"exact"},{"name":"inhibition of adult salivary gland determination","type":"narrow"},{"name":"negative regulation of adult salivary gland determination","type":"exact"}],"termid":"GO:0045709"}


id: MONDO:0013049
data:
  {"annotated_genes":["SJAG_00831"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86943],"is_not":false,"summary":null,"term":"MONDO:0013049"},{"annotations":[87033],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0033556"}]},"cv_name":"mondo","definition":"DPM3-CDG is an extremely rare form of CDG syndrome characterized clinically in the single reported case by muscle weakness, waddling gait and dilated cardiomyopathy.","definition_xrefs":["Orphanet:263494"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"familial dilated cardiomyopathy","termid":"MONDO:0016333"},{"relation_name":"is_a","term_name":"congenital disorder of glycosylation type I","termid":"MONDO:0005500"},{"relation_name":"is_a","term_name":"disorder of multiple glycosylation","termid":"MONDO:0017749"},{"relation_name":"is_a","term_name":"muscular dystrophy-dystroglycanopathy","termid":"MONDO:0018276"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00831":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"},{"rel_name":"is_a","termid":"MONDO:0002320"},{"rel_name":"is_a","termid":"MONDO:0024322"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005336","MONDO:0024322","MONDO:0002320","MONDO:0005066"],"is_obsolete":false,"name":"DPM3-congenital disorder of glycosylation","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:414534","SCTID:725044000","UMLS:C2752007","MESH:C567857","OMIM:612937","GARD:12395"],"synonyms":[{"name":"CDG Io","type":"related"},{"name":"CDG syndrome type Io","type":"exact"},{"name":"CDG-Io","type":"exact"},{"name":"CDG1O","type":"exact"},{"name":"CDGIo","type":"related"},{"name":"Cdg1(Dpm3)","type":"related"},{"name":"DG1O","type":"related"},{"name":"DPM3-CDG","type":"exact"},{"name":"DPM3-CDG (CDG-Io)","type":"related"},{"name":"DPM3-congenital disorder of glycosylation","type":"exact"},{"name":"carbohydrate deficient glycoprotein syndrome type Io","type":"exact"},{"name":"congenital disorder of glycosylation type 1o","type":"exact"},{"name":"congenital disorder of glycosylation type Io","type":"exact"},{"name":"congenital disorder of glycosylation, type Io","type":"related"},{"name":"muscular dystrophy-dystroglycanopathy (limb-girdle), type C, 15","type":"exact"}],"termid":"MONDO:0013049","terms_by_termid":{"MONDO:0013049":null,"MONDO:0033556":null},"xrefs":{"Monarch":{"xref_id":"0013049"}}}


id: PBO:0049086
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"G protein-coupled receptor 141B, pseudogene","termid":"PBO:0049086"}


id: MONDO:0030971
data:
  {"annotated_genes":["SJAG_04928"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87342],"is_not":false,"summary":null,"term":"MONDO:0030971"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"immunodeficiency disease","termid":"MONDO:0021094"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04928":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"immunodeficiency 78 with autoimmunity and developmental delay","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C5543159","OMIM:619220","MEDGEN:1785772"],"synonyms":[{"name":"IMD78","type":"exact"},{"name":"TPP2 deficiency","type":"exact"},{"name":"immunodeficiency 78 with autoimmunity and developmental delay","type":"exact"}],"termid":"MONDO:0030971","terms_by_termid":{"MONDO:0030971":null},"xrefs":{"Monarch":{"xref_id":"0030971"}}}


id: PBO:0071212
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L23a pseudogene 53","termid":"PBO:0071212"}


id: GO:0048840
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the otolith over time, from its formation to the mature structure.","definition_xrefs":["GOC:sr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure development","termid":"GO:0048856"},{"relation_name":"part_of","term_name":"inner ear development","termid":"GO:0048839"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"otolith development","termid":"GO:0048840"}


id: _global:results_in_acquisition_of_features_of
data:
  {"annotation_feature_type":"gene","cv_name":"go/extensions/gorel","definition":"The relationship that links a specified entity with the process that results in an unspecified entity acquiring the features and characteristics of the specified entity","direct_ancestors":[{"relation_name":"is_a","term_name":"has_participant","termid":"RO:0000057"},{"relation_name":"is_a","term_name":"go_annotation_extension_relation","termid":"_global:go_annotation_extension_relation"},{"relation_name":"is_a","term_name":"results_in_changes_to_anatomical_or_cellular_structure","termid":"_global:results_in_changes_to_anatomical_or_cellular_structure"},{"relation_name":"is_a","term_name":"results_in_developmental_progression_of","termid":"_global:results_in_developmental_progression_of"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"results_in_acquisition_of_features_of","secondary_identifiers":["GOREL:0001014","RO:0002315"],"synonyms":[{"name":"results in differentiation of","type":"exact"}],"termid":"_global:results_in_acquisition_of_features_of"}


id: GO:0019508
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine to form fumarate. 2,5-dihydroxypyridine is dioxygenated to give maleamate and formate; the maleamate from this reaction is then converted to maleate, which is then isomerized to fumurate.","definition_xrefs":["MetaCyc:PWY-722"],"direct_ancestors":[{"relation_name":"is_a","term_name":"fumarate metabolic process","termid":"GO:0006106"},{"relation_name":"is_a","term_name":"2,5-dihydroxypyridine catabolic process","termid":"GO:0051166"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0008150"],"is_obsolete":false,"name":"2,5-dihydroxypyridine catabolic process to fumarate","synonyms":[{"name":"2,5-dihydroxypyridine breakdown to fumarate","type":"exact"},{"name":"2,5-dihydroxypyridine degradation to fumarate","type":"exact"},{"name":"2,5-dihydroxypyridine utilization","type":"related"},{"name":"maleamate pathway","type":"exact"},{"name":"pyridine-2,5-diol catabolic process to fumarate","type":"exact"}],"termid":"GO:0019508"}


id: PBO:0068997
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 241, pseudogene","termid":"PBO:0068997"}


id: GO:0060707
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized cell acquires specialized features of a trophoblast giant cell of the placenta. Trophoblast giant cells are the cell of the placenta that line the maternal decidua.","definition_xrefs":["GOC:dph","PMID:16269175"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell differentiation involved in embryonic placenta development","termid":"GO:0060706"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"trophoblast giant cell differentiation","termid":"GO:0060707"}


id: PATO:0002120
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A quality inhering a bearer by virtue of the bearer's ability to generate pus.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"composition","termid":"PATO:0000025"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"suppurative","synonyms":[{"name":"purulent","type":"related"}],"termid":"PATO:0002120"}


id: PBO:0057702
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 1289-2","termid":"PBO:0057702"}


id: GO:0140754
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in intracellular membranes are reorganized by viral proteins that perturb membrane integrity and can cause an extensive rearrangement of cellular membranes, forming membranous webs, which are thought to be the site of replication or certain viruses, for example the HPV virus.","definition_xrefs":["PMID:19376974"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated perturbation of host membrane","termid":"GO:0141171"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"reorganization of cellular membranes to establish viral sites of replication","termid":"GO:0140754"}


id: GO:0052132
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"gene_count":0,"genotype_count":0,"name":"obsolete positive aerotaxis on or near host (obsolete GO:0052132)","termid":"GO:0052132"}


id: MONDO:0014628
data:
  {"annotated_genes":["SJAG_00233"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87015],"is_not":false,"summary":null,"term":"MONDO:0014628"}]},"cv_name":"mondo","definition":"Any bilateral striopallidodentate calcinosis in which the cause of the disease is a mutation in the XPR1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bilateral striopallidodentate calcinosis","termid":"MONDO:0008947"},{"relation_name":"is_a","term_name":"idiopathic disease","termid":"MONDO:0700007"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00233":null},"genotype_count":0,"is_obsolete":false,"name":"basal ganglia calcification, idiopathic, 6","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C4225335","OMIM:616413","GARD:16107","MEDGEN:901404"],"synonyms":[{"name":"IBGC6","type":"related"},{"name":"XPR1 bilateral striopallidodentate calcinosis","type":"exact"},{"name":"basal ganglia calcification, idiopathic, 6","type":"exact"},{"name":"basal ganglia calcification, idiopathic, type 6","type":"exact"},{"name":"bilateral striopallidodentate calcinosis caused by mutation in XPR1","type":"exact"}],"termid":"MONDO:0014628","terms_by_termid":{"MONDO:0014628":null},"xrefs":{"Monarch":{"xref_id":"0014628"}}}


id: SOFP:qseq_type
data:
  {"annotation_feature_type":"gene","cv_name":"feature_property","direct_ancestors":[{"relation_name":"is_a","term_name":"feature_property","termid":"SOFP:feature_property"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"qseq_type","termid":"SOFP:qseq_type"}


id: GO:0120214
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of histidine biosynthetic process.","definition_xrefs":["GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of small molecule metabolic process","termid":"GO:0062014"},{"relation_name":"is_a","term_name":"regulation of histidine biosynthetic process","termid":"GO:0120213"},{"relation_name":"is_a","term_name":"negative regulation of amino acid biosynthetic process","termid":"GO:2000283"},{"relation_name":"negatively_regulates","term_name":"L-histidine biosynthetic process","termid":"GO:0000105"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006520"},{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"negatively_regulates","termid":"GO:0044281"},{"rel_name":"negatively_regulates","termid":"GO:0006520"}],"interesting_parent_ids":["GO:0006520","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"negative regulation of histidine biosynthetic process","synonyms":[{"name":"down regulation of histidine anabolism","type":"exact"},{"name":"down regulation of histidine biosynthesis","type":"exact"},{"name":"down regulation of histidine biosynthetic process","type":"exact"},{"name":"down regulation of histidine formation","type":"exact"},{"name":"down regulation of histidine synthesis","type":"exact"},{"name":"down-regulation of histidine anabolism","type":"exact"},{"name":"down-regulation of histidine biosynthesis","type":"exact"},{"name":"down-regulation of histidine biosynthetic process","type":"exact"},{"name":"down-regulation of histidine formation","type":"exact"},{"name":"down-regulation of histidine synthesis","type":"exact"},{"name":"downregulation of histidine anabolism","type":"exact"},{"name":"downregulation of histidine biosynthesis","type":"exact"},{"name":"downregulation of histidine biosynthetic process","type":"exact"},{"name":"downregulation of histidine formation","type":"exact"},{"name":"downregulation of histidine synthesis","type":"exact"},{"name":"inhibition of histidine anabolism","type":"narrow"},{"name":"inhibition of histidine biosynthesis","type":"narrow"},{"name":"inhibition of histidine biosynthetic process","type":"narrow"},{"name":"inhibition of histidine formation","type":"narrow"},{"name":"inhibition of histidine synthesis","type":"narrow"},{"name":"negative regulation of histidine anabolism","type":"exact"},{"name":"negative regulation of histidine biosynthesis","type":"exact"},{"name":"negative regulation of histidine formation","type":"exact"},{"name":"negative regulation of histidine synthesis","type":"exact"}],"termid":"GO:0120214"}


id: MONDO:0015635
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare, congenital disorder of the eccrine sweat ducts that presents as grouped keratotic papules and plaques with a linear distribution and/or multiple punctate pits filled with tiny keratotic plugs resembling comedones. The lesion are usually located on the acral portion of a limb.","definition_xrefs":["NCIT:C4740"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete inherited skin tumor (obsolete MONDO:0015950)","termid":"MONDO:0015950"},{"relation_name":"is_a","term_name":"melanocytic nevus","termid":"MONDO:0005073"},{"relation_name":"is_a","term_name":"benign eccrine neoplasm","termid":"MONDO:0024247"},{"relation_name":"is_a","term_name":"eccrine sweat gland hamartoma","termid":"MONDO:0024482"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"porokeratotic eccrine ostial and dermal duct nevus","secondary_identifiers":["SCTID:239118007","GARD:20070","MEDGEN:96880","Orphanet:166286","UMLS:C0473579"],"synonyms":[{"name":"Porokeratotic eccrine duct and hair follicle Nevus","type":"exact"},{"name":"Porokeratotic eccrine nevus","type":"exact"},{"name":"comedo nevus of the palm","type":"exact"},{"name":"linear eccrine Nevus with comedones","type":"exact"}],"termid":"MONDO:0015635","xrefs":{"Monarch":{"xref_id":"0015635"}}}


id: PBO:0048806
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GNB1 divergent transcript","termid":"PBO:0048806"}


id: MONDO:0018376
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"secondary avascular necrosis","termid":"MONDO:0018374"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"secondary non-traumatic avascular necrosis","secondary_identifiers":["Orphanet:399180","UMLS:C5192430","MEDGEN:1684106","GARD:21661"],"synonyms":[{"name":"secondary non-traumatic AVN","type":"exact"}],"termid":"MONDO:0018376","xrefs":{"Monarch":{"xref_id":"0018376"}}}


id: GO:0021912
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results the commitment of a cell to become a motor neuron in the ventral spinal cord.","definition_xrefs":["GOC:jid","PMID:11262869","GOC:dgh","GOC:dph","GOC:cls","GO_REF:0000021"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification (obsolete GO:0021912)","termid":"GO:0021912"}


id: GO:1901561
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benomyl stimulus.","definition_xrefs":["GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete response to benomyl (obsolete GO:1901561)","termid":"GO:1901561"}


id: PBO:0113495
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Translation elongation factor 3; contains two ABC cassettes; binds and hydrolyzes ATP; interacts with mRNA independently of translation; involved in frameshifting at stalled ribosomes; YEF3 has a paralog, HEF3, that arose from the whole genome duplication","termid":"PBO:0113495"}


id: PBO:0061986
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 2 subfamily B member 6","termid":"PBO:0061986"}


id: GO:0030097
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.","definition_xrefs":["GOC:dgh","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell development","termid":"GO:0048468"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"hemopoiesis","secondary_identifiers":["Wikipedia:Haematopoiesis"],"synonyms":[{"name":"blood cell biosynthesis","type":"exact"},{"name":"blood cell formation","type":"exact"},{"name":"haemopoiesis","type":"exact"},{"name":"hematopoiesis","type":"exact"}],"termid":"GO:0030097"}


id: GO:0010745
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.","definition_xrefs":["GOC:add","GOC:tb","GOC:BHF","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of macrophage derived foam cell differentiation","termid":"GO:0010743"},{"relation_name":"is_a","term_name":"negative regulation of cell differentiation","termid":"GO:0045596"},{"relation_name":"negatively_regulates","term_name":"macrophage derived foam cell differentiation","termid":"GO:0010742"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of macrophage derived foam cell differentiation","termid":"GO:0010745"}


id: PBO:0028031
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-delayed_onset_of_premeiotic_DNA_replication","termid":"PBO:0028031"}


id: PBO:0070983
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L19 pseudogene 7","termid":"PBO:0070983"}


id: GO:0030010
data:
  {"annotated_genes":["SJAG_02838","SJAG_03126","SJAG_03625","SJAG_04724","SJAG_03754","SJAG_03705","SJAG_01373","SJAG_03453","SJAG_00594","SJAG_04509","SJAG_00140","SJAG_02695","SJAG_01456","SJAG_00216","SJAG_03596","SJAG_00514","SJAG_04653","SJAG_02737","SJAG_03581","SJAG_00317","SJAG_00845","SJAG_04522","SJAG_01794","SJAG_02651","SJAG_02536","SJAG_03486","SJAG_04624","SJAG_00030","SJAG_01901","SJAG_04322"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[72476,80108,81901,92655,94082,95287,99009,116659],"is_not":false,"summary":null,"term":"GO:0030010"},{"annotations":[89869,101556,108686,119764,118340,105306,112610],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051523"},{"annotations":[94402,106475,121490],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061171"},{"annotations":[98788,106698,78075,118808,106367],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0000132"},{"annotations":[92773],"is_not":false,"rel_names":["regulates","negatively_regulates"],"summary":null,"term":"GO:1904846"},{"annotations":[109446,114328,105517],"is_not":false,"rel_names":["positively_regulates","regulates"],"summary":null,"term":"GO:0061173"},{"annotations":[118446,109447],"is_not":false,"rel_names":["regulates","positively_regulates"],"summary":null,"term":"GO:2000784"},{"annotations":[96396,70813],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:2000114"}]},"cv_name":"biological_process","definition":"The specification and formation of anisotropic intracellular organization or cell growth patterns.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"establishment or maintenance of cell polarity","termid":"GO:0007163"}],"gene_count":30,"genes_by_uniquename":{"SJAG_00030":null,"SJAG_00140":null,"SJAG_00216":null,"SJAG_00317":null,"SJAG_00514":null,"SJAG_00594":null,"SJAG_00845":null,"SJAG_01373":null,"SJAG_01456":null,"SJAG_01794":null,"SJAG_01901":null,"SJAG_02536":null,"SJAG_02651":null,"SJAG_02695":null,"SJAG_02737":null,"SJAG_02838":null,"SJAG_03126":null,"SJAG_03453":null,"SJAG_03486":null,"SJAG_03581":null,"SJAG_03596":null,"SJAG_03625":null,"SJAG_03705":null,"SJAG_03754":null,"SJAG_04322":null,"SJAG_04509":null,"SJAG_04522":null,"SJAG_04624":null,"SJAG_04653":null,"SJAG_04724":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0007163"}],"interesting_parent_ids":["GO:0007163","GO:0008150"],"is_obsolete":false,"name":"establishment of cell polarity","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null,"GO_REF:0000117":null,"PMID:30664646":null},"secondary_identifiers":["GO:0000283","GO:0030468"],"synonyms":[{"name":"bud site selection/establishment of cell polarity","type":"narrow"},{"name":"cell polarization","type":"exact"}],"termid":"GO:0030010","terms_by_termid":{"GO:0000132":null,"GO:0030010":null,"GO:0051523":null,"GO:0061171":null,"GO:0061173":null,"GO:1904846":null,"GO:2000114":null,"GO:2000784":null}}


id: MONDO:0004444
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare morphologic variant of bladder carcinoma characterized by the presence of malignant glandular epithelial cells and clear cells forming a tubulo-cystic pattern.","definition_xrefs":["NCIT:C39847"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bladder clear cell adenocarcinoma","termid":"MONDO:0003386"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"bladder tubulo-cystic clear cell adenocarcinoma","secondary_identifiers":["DOID:8050","UMLS:C1511203","MEDGEN:267060"],"synonyms":[{"name":"bladder tubulo-cystic clear cell adenocarcinoma","type":"exact"}],"termid":"MONDO:0004444","xrefs":{"Monarch":{"xref_id":"0004444"}}}


id: GO:0000820
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of amino acid metabolic process","termid":"GO:0006521"},{"relation_name":"is_a","term_name":"regulation of small molecule metabolic process","termid":"GO:0062012"},{"relation_name":"regulates","term_name":"glutamine family amino acid metabolic process","termid":"GO:0009064"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006520"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0044281","GO:0006520","GO:0008150"],"is_obsolete":false,"name":"regulation of glutamine family amino acid metabolic process","synonyms":[{"name":"regulation of glutamine family amino acid metabolism","type":"exact"}],"termid":"GO:0000820"}


id: GO:1900197
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of penicillin biosynthetic process.","definition_xrefs":["GOC:di","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of penicillin metabolic process","termid":"GO:0033245"},{"relation_name":"is_a","term_name":"regulation of penicillin biosynthetic process","termid":"GO:1900196"},{"relation_name":"is_a","term_name":"negative regulation of secondary metabolite biosynthetic process","termid":"GO:1900377"},{"relation_name":"negatively_regulates","term_name":"penicillin biosynthetic process","termid":"GO:0042318"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0019748"},{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"regulates","termid":"GO:0006790"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0044281"},{"rel_name":"negatively_regulates","termid":"GO:0006790"},{"rel_name":"regulates","termid":"GO:0019748"}],"interesting_parent_ids":["GO:0008150","GO:0044281","GO:0006790","GO:0019748"],"is_obsolete":false,"name":"negative regulation of penicillin biosynthetic process","synonyms":[{"name":"down regulation of penicillin anabolism","type":"exact"},{"name":"down regulation of penicillin biosynthesis","type":"exact"},{"name":"down regulation of penicillin biosynthetic process","type":"exact"},{"name":"down regulation of penicillin formation","type":"exact"},{"name":"down regulation of penicillin synthesis","type":"exact"},{"name":"down-regulation of penicillin anabolism","type":"exact"},{"name":"down-regulation of penicillin biosynthesis","type":"exact"},{"name":"down-regulation of penicillin biosynthetic process","type":"exact"},{"name":"down-regulation of penicillin formation","type":"exact"},{"name":"down-regulation of penicillin synthesis","type":"exact"},{"name":"downregulation of penicillin anabolism","type":"exact"},{"name":"downregulation of penicillin biosynthesis","type":"exact"},{"name":"downregulation of penicillin biosynthetic process","type":"exact"},{"name":"downregulation of penicillin formation","type":"exact"},{"name":"downregulation of penicillin synthesis","type":"exact"},{"name":"inhibition of penicillin anabolism","type":"exact"},{"name":"inhibition of penicillin biosynthesis","type":"exact"},{"name":"inhibition of penicillin biosynthetic process","type":"narrow"},{"name":"inhibition of penicillin formation","type":"exact"},{"name":"inhibition of penicillin synthesis","type":"exact"},{"name":"negative regulation of penicillin anabolism","type":"exact"},{"name":"negative regulation of penicillin biosynthesis","type":"exact"},{"name":"negative regulation of penicillin formation","type":"exact"},{"name":"negative regulation of penicillin synthesis","type":"exact"}],"termid":"GO:1900197"}


id: GO:0160226
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"An oligosaccharyltransferase complex that contains STT3A as the catalytic subunit.","definition_xrefs":["PMID:31831667","PMID:39509507"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oligosaccharyltransferase complex","termid":"GO:0008250"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"part_of","termid":"GO:0005789"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005783"}],"interesting_parent_ids":["GO:0005737","GO:0005789","GO:0005575","GO:0005783","GO:0032991"],"is_obsolete":false,"name":"oligosaccharyltransferase complex A","synonyms":[{"name":"OST-A","type":"exact"}],"termid":"GO:0160226"}


id: MONDO:0035930
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Neu-Laxova syndrome","termid":"MONDO:0000179"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0002320"},{"rel_name":"is_a","termid":"MONDO:0004736"}],"interesting_parent_ids":["MONDO:0002320","MONDO:0004736","MONDO:0005066"],"is_obsolete":false,"name":"neu-laxova syndrome due to 3-phosphoserine phosphatase deficiency","secondary_identifiers":["GARD:22337","MEDGEN:1843313","UMLS:C5680338","Orphanet:583612"],"synonyms":[{"name":"3-phosphoserine phosphatase deficiency, prenatal form","type":"exact"}],"termid":"MONDO:0035930","xrefs":{"Monarch":{"xref_id":"0035930"}}}


id: PBO:0003630
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"conserved fungal protein, involved in endocytic trafficking (predicted)","termid":"PBO:0003630"}


id: PBO:0042872
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cilia and flagella associated protein 107","termid":"PBO:0042872"}


id: PR:Q10336
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mcp6 gene.","definition_xrefs":["UniProtKB:Q10336","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiotic coiled-coil protein 6 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC582.06c","synonyms":[{"name":"Spom972h-mcp6","type":"exact"},{"name":"horsetail movement protein hrs1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"meiotically up-regulated gene 3 protein (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q10336"}


id: MONDO:0003836
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare, hormonally functioning or non-functioning pituitary gland adenocarcinoma that produces thyrotropin.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"TSH producing pituitary tumor","termid":"MONDO:0003837"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"malignant thyroid stimulating hormone producing neoplasm of pituitary gland","secondary_identifiers":["UMLS:C1334627","MEDGEN:277341","NCIT:C5965","DOID:6274"],"synonyms":[{"name":"TSH producing pituitary gland carcinoma","type":"exact"},{"name":"TSH-producing pituitary gland carcinoma","type":"exact"},{"name":"malignant TSH producing neoplasm of pituitary","type":"exact"},{"name":"malignant TSH producing neoplasm of pituitary gland","type":"exact"},{"name":"malignant TSH producing neoplasm of the pituitary","type":"exact"},{"name":"malignant TSH producing neoplasm of the pituitary gland","type":"exact"},{"name":"malignant TSH producing pituitary gland neoplasm","type":"exact"},{"name":"malignant TSH producing pituitary gland tumor","type":"exact"},{"name":"malignant TSH producing pituitary gland tumour","type":"exact"},{"name":"malignant TSH producing pituitary neoplasm","type":"exact"},{"name":"malignant TSH producing pituitary tumor","type":"exact"},{"name":"malignant TSH producing pituitary tumour","type":"exact"},{"name":"malignant TSH producing tumor of pituitary","type":"exact"},{"name":"malignant TSH producing tumor of pituitary gland","type":"exact"},{"name":"malignant TSH producing tumor of the pituitary","type":"exact"},{"name":"malignant TSH producing tumor of the pituitary gland","type":"exact"},{"name":"malignant TSH producing tumour of pituitary","type":"exact"},{"name":"malignant TSH producing tumour of pituitary gland","type":"exact"},{"name":"malignant TSH producing tumour of the pituitary","type":"exact"},{"name":"malignant TSH producing tumour of the pituitary gland","type":"exact"},{"name":"malignant TSH secreting neoplasm of pituitary","type":"exact"},{"name":"malignant TSH secreting neoplasm of pituitary gland","type":"exact"},{"name":"malignant TSH secreting neoplasm of the pituitary","type":"exact"},{"name":"malignant TSH secreting neoplasm of the pituitary gland","type":"exact"},{"name":"malignant TSH secreting pituitary gland neoplasm","type":"exact"},{"name":"malignant TSH secreting pituitary gland tumor","type":"exact"},{"name":"malignant TSH secreting pituitary gland tumour","type":"exact"},{"name":"malignant TSH secreting pituitary neoplasm","type":"exact"},{"name":"malignant TSH secreting pituitary tumor","type":"exact"},{"name":"malignant TSH secreting pituitary tumour","type":"exact"},{"name":"malignant TSH secreting tumor of pituitary","type":"exact"},{"name":"malignant TSH secreting tumor of pituitary gland","type":"exact"},{"name":"malignant TSH secreting tumor of the pituitary","type":"exact"},{"name":"malignant TSH secreting tumor of the pituitary gland","type":"exact"},{"name":"malignant TSH secreting tumour of pituitary","type":"exact"},{"name":"malignant TSH secreting tumour of pituitary gland","type":"exact"},{"name":"malignant TSH secreting tumour of the pituitary","type":"exact"},{"name":"malignant TSH secreting tumour of the pituitary gland","type":"exact"},{"name":"malignant pituitary gland thyrotropinoma","type":"exact"},{"name":"malignant pituitary thyrotropinoma","type":"exact"},{"name":"malignant thyroid stimulating hormone producing neoplasm of pituitary","type":"exact"},{"name":"malignant thyroid stimulating hormone producing neoplasm of pituitary gland","type":"exact"},{"name":"malignant thyroid stimulating hormone producing neoplasm of the pituitary","type":"exact"},{"name":"malignant thyroid stimulating hormone producing neoplasm of the pituitary gland","type":"exact"},{"name":"malignant thyroid stimulating hormone producing pituitary gland neoplasm","type":"exact"},{"name":"malignant thyroid stimulating hormone producing pituitary gland tumor","type":"exact"},{"name":"malignant thyroid stimulating hormone producing pituitary gland tumour","type":"exact"},{"name":"malignant thyroid stimulating hormone producing pituitary neoplasm","type":"exact"},{"name":"malignant thyroid stimulating hormone producing pituitary tumor","type":"exact"},{"name":"malignant thyroid stimulating hormone producing pituitary tumour","type":"exact"},{"name":"malignant thyroid stimulating hormone producing tumor","type":"exact"},{"name":"malignant thyroid stimulating hormone producing tumor of pituitary","type":"exact"},{"name":"malignant thyroid stimulating hormone producing tumor of pituitary gland","type":"exact"},{"name":"malignant thyroid stimulating hormone producing tumor of the pituitary","type":"exact"},{"name":"malignant thyroid stimulating hormone producing tumor of the pituitary gland","type":"exact"},{"name":"malignant thyroid stimulating hormone producing tumour","type":"exact"},{"name":"malignant thyroid stimulating hormone producing tumour of pituitary","type":"exact"},{"name":"malignant thyroid stimulating hormone producing tumour of pituitary gland","type":"exact"},{"name":"malignant thyroid stimulating hormone producing tumour of the pituitary","type":"exact"},{"name":"malignant thyroid stimulating hormone producing tumour of the pituitary gland","type":"exact"},{"name":"malignant thyroid stimulating hormone secreting neoplasm of pituitary","type":"exact"},{"name":"malignant thyroid stimulating hormone secreting neoplasm of pituitary gland","type":"exact"},{"name":"malignant thyroid stimulating hormone secreting neoplasm of the pituitary","type":"exact"},{"name":"malignant thyroid stimulating hormone secreting neoplasm of the pituitary gland","type":"exact"},{"name":"malignant thyroid stimulating hormone secreting pituitary gland neoplasm","type":"exact"},{"name":"malignant thyroid stimulating hormone secreting pituitary gland tumor","type":"exact"},{"name":"malignant thyroid stimulating hormone secreting pituitary gland tumour","type":"exact"},{"name":"malignant thyroid stimulating hormone secreting pituitary neoplasm","type":"exact"},{"name":"malignant thyroid stimulating hormone secreting pituitary tumor","type":"exact"},{"name":"malignant thyroid stimulating hormone secreting pituitary tumour","type":"exact"},{"name":"malignant thyroid stimulating hormone secreting tumor of pituitary","type":"exact"},{"name":"malignant thyroid stimulating hormone secreting tumor of pituitary gland","type":"exact"},{"name":"malignant thyroid stimulating hormone secreting tumor of the pituitary","type":"exact"},{"name":"malignant thyroid stimulating hormone secreting tumor of the pituitary gland","type":"exact"},{"name":"malignant thyroid stimulating hormone secreting tumour of pituitary","type":"exact"},{"name":"malignant thyroid stimulating hormone secreting tumour of pituitary gland","type":"exact"},{"name":"malignant thyroid stimulating hormone secreting tumour of the pituitary","type":"exact"},{"name":"malignant thyroid stimulating hormone secreting tumour of the pituitary gland","type":"exact"},{"name":"malignant thyrotropinoma","type":"exact"},{"name":"malignant thyrotropinoma of pituitary","type":"exact"},{"name":"malignant thyrotropinoma of pituitary gland","type":"exact"},{"name":"malignant thyrotropinoma of the pituitary","type":"exact"},{"name":"malignant thyrotropinoma of the pituitary gland","type":"exact"},{"name":"thyrotropin producing pituitary gland carcinoma","type":"exact"}],"termid":"MONDO:0003836","xrefs":{"Monarch":{"xref_id":"0003836"}}}


id: PBO:0088064
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ubiquitin-ribosomal 60S subunit protein L40A fusion protein; cleaved to yield ubiquitin and ribosomal protein L40A; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes; homologous to mammalian ribosomal protein L40, no bacterial homolog; RPL40A has a paralog, RPL40B, that arose from the whole genome duplication; relative distribution to the nucleus increases upon DNA replication stress","termid":"PBO:0088064"}


id: GO:0031131
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process in which one cell or group of cells receives, transduces, and responds to a signal generated by another cell or group of cells of different ancestry and developmental potential, such that the recipient cell(s) undergo a developmental change.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete reception of an inductive signal (obsolete GO:0031131)","termid":"GO:0031131"}


id: MONDO:0018874
data:
  {"annotated_genes":["SJAG_01349","SJAG_05979","SJAG_01748","SJAG_03453","SJAG_01013","SJAG_03905"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[89021,89022,89023,89024,89178,89179],"is_not":false,"summary":null,"term":"MONDO:0018874"}]},"cv_name":"mondo","definition":"Acute myeloid leukemia (AML) is a group of neoplasms arising from precursor cells committed to the myeloid cell-line differentiation. All of them are characterized by clonal expansion of myeloid blasts. AML manifests by fever, pallor, anemia, hemorrhages and recurrent infections.","definition_xrefs":["Orphanet:519"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myeloid leukemia","termid":"MONDO:0004643"},{"relation_name":"is_a","term_name":"acute leukemia","termid":"MONDO:0010643"}],"gene_count":6,"genes_by_uniquename":{"SJAG_01013":null,"SJAG_01349":null,"SJAG_01748":null,"SJAG_03453":null,"SJAG_03905":null,"SJAG_05979":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0004992","MONDO:0005570"],"is_obsolete":false,"name":"acute myeloid leukemia","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["DOID:9119","EFO:0000222","ICD9:205.0","ICD10CM:C92.0","MEDGEN:9730","SCTID:91861009","GARD:12757","MedDRA:10000880","NORD:1905","UMLS:C0023467","ICD9:205.00","NCIT:C3171","MESH:D015470","OMIM:601626","ONCOTREE:AML","ICDO:9861/3"],"synonyms":[{"name":"AML","type":"exact"},{"name":"AML - acute myeloid leukaemia","type":"exact"},{"name":"AML - acute myeloid leukemia","type":"exact"},{"name":"ANLL","type":"exact"},{"name":"acute Nonlymphocytic leukaemia","type":"exact"},{"name":"acute Nonlymphocytic leukemia","type":"exact"},{"name":"acute granulocytic leukaemia","type":"exact"},{"name":"acute granulocytic leukemia","type":"exact"},{"name":"acute myeloblastic leukaemia","type":"exact"},{"name":"acute myeloblastic leukemia","type":"exact"},{"name":"acute myelocytic leukaemia","type":"exact"},{"name":"acute myelocytic leukemia","type":"exact"},{"name":"acute myelogenous leukaemia","type":"exact"},{"name":"acute myelogenous leukemia","type":"exact"},{"name":"acute myelogenous leukemias","type":"exact"},{"name":"acute myeloid leukaemia (AML)","type":"exact"},{"name":"acute myeloid leukemia","type":"exact"},{"name":"acute myeloid leukemia (AML)","type":"exact"},{"name":"acute myeloid leukemia, somatic","type":"exact"},{"name":"acute non lymphoblastic leukaemia","type":"related"},{"name":"acute non lymphoblastic leukemia","type":"related"},{"name":"acute nonlymphocytic leukaemia","type":"exact"},{"name":"acute nonlymphocytic leukemia","type":"exact"},{"name":"hematopoeitic - acute Myleogenous leukaemia (AML)","type":"exact"},{"name":"hematopoeitic - acute Myleogenous leukemia (AML)","type":"exact"},{"name":"leukemia, acute myelogenous","type":"related"},{"name":"leukemia, acute myeloid","type":"related"},{"name":"leukemia, acute myeloid, autosomal dominant, somatic mutation","type":"exact"},{"name":"leukemia, acute myeloid, reduced survival in, somatic","type":"exact"},{"name":"leukemia, acute myeloid, somatic","type":"exact"},{"name":"leukemia, acute myeloid, susceptibility to","type":"related"},{"name":"leukemia, acute myeloid, susceptibility to, autosomal dominant, somatic mutation","type":"exact"},{"name":"leukemia, myelocytic, acute","type":"exact"},{"name":"myeloid leukemia, acute","type":"exact"},{"name":"myeloid leukemia, acute, M4/M4Eo subtype, somatic","type":"exact"}],"termid":"MONDO:0018874","terms_by_termid":{"MONDO:0018874":null},"xrefs":{"Monarch":{"xref_id":"0018874"}}}


id: PBO:0051088
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin heavy joining 1","termid":"PBO:0051088"}


id: GO:0043311
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of eosinophil degranulation.","definition_xrefs":["ISBN:0781735149"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of myeloid leukocyte mediated immunity","termid":"GO:0002888"},{"relation_name":"is_a","term_name":"positive regulation of leukocyte degranulation","termid":"GO:0043302"},{"relation_name":"is_a","term_name":"regulation of eosinophil degranulation","termid":"GO:0043309"},{"relation_name":"is_a","term_name":"positive regulation of immune response","termid":"GO:0050778"},{"relation_name":"positively_regulates","term_name":"eosinophil degranulation","termid":"GO:0043308"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0016192"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"positively_regulates","termid":"GO:0016192"},{"rel_name":"positively_regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0016192","GO:0008150"],"is_obsolete":false,"name":"positive regulation of eosinophil degranulation","synonyms":[{"name":"activation of eosinophil degranulation","type":"narrow"},{"name":"positive regulation of eosinophil granule exocytosis","type":"exact"},{"name":"stimulation of eosinophil degranulation","type":"narrow"},{"name":"up regulation of eosinophil degranulation","type":"exact"},{"name":"up-regulation of eosinophil degranulation","type":"exact"},{"name":"upregulation of eosinophil degranulation","type":"exact"}],"termid":"GO:0043311"}


id: MONDO:0001233
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"acute orbital inflammation","termid":"MONDO:0001230"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"orbital tenonitis","secondary_identifiers":["DOID:11233","SCTID:8976003","ICD9:376.04","MEDGEN:509879","UMLS:C0155259"],"synonyms":[{"name":"tenonitis","type":"exact"}],"termid":"MONDO:0001233","xrefs":{"Monarch":{"xref_id":"0001233"}}}


id: MONDO:0011507
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"diabetes mellitus, congenital autoimmune","secondary_identifiers":["OMIM:605026","MESH:C565730","UMLS:C1857958","MEDGEN:347586"],"synonyms":[{"name":"diabetes mellitus, congenital autoimmune","type":"exact"}],"termid":"MONDO:0011507","xrefs":{"Monarch":{"xref_id":"0011507"}}}


id: MOD:01991
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts a glycinium (protonated glycine) residue to an N,N,N-trimethylglycine.","definition_xrefs":["PubMed:23978223","ChEBI:17750","PubMed:23818633","RESID:AA0619"],"direct_ancestors":[{"relation_name":"derives_from","term_name":"protonated glycine (glycinium) residue","termid":"MOD:01990"},{"relation_name":"is_a","term_name":"alpha-amino trimethylated residue","termid":"MOD:01687"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00427"}],"interesting_parent_ids":["MOD:00427"],"is_obsolete":false,"name":"N,N,N-trimethylglycine (from glycinium)","synonyms":[{"name":"N2Me3Gly","type":"exact"}],"termid":"MOD:01991"}


id: GO:1905912
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of calcium ion export across the plasma membrane.","definition_xrefs":["GOC:rph","GOC:TermGenie","GO_REF:0000058","GOC:BHF","GOC:BHF_miRNA","PMID:22362515"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of calcium ion transmembrane transport","termid":"GO:1903169"},{"relation_name":"regulates","term_name":"calcium ion export across plasma membrane","termid":"GO:1990034"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0055085"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0055085","GO:0006810"],"is_obsolete":false,"name":"regulation of calcium ion export across plasma membrane","synonyms":[{"name":"regulation of calcium ion efflux from cell","type":"exact"},{"name":"regulation of calcium ion export from cell","type":"exact"}],"termid":"GO:1905912"}


id: PBO:0069503
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 770, pseudogene","termid":"PBO:0069503"}


id: GO:0060086
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any homeostatic process in which an organism modulates its internal body temperature at different values with a regularity of approximately 24 hours.","definition_xrefs":["GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"temperature homeostasis","termid":"GO:0001659"},{"relation_name":"is_a","term_name":"circadian rhythm","termid":"GO:0007623"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"circadian temperature homeostasis","synonyms":[{"name":"circadian regulation of body temperature","type":"related"},{"name":"circadian thermoregulation","type":"exact"}],"termid":"GO:0060086"}


id: GO:0140449
data:
  {"annotated_genes":["SJAG_01745"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[93161],"is_not":false,"summary":null,"term":"GO:0140449"}]},"cv_name":"molecular_function","definition":"The binding activity of a molecule that brings together the centromeric region of a chromosome and the inner nuclear membrane by interacting with both the centromere/kinetochore complex and the nuclear membrane, in order to establish and maintain the centromere/kinetochore location.","definition_xrefs":["PMID:31635174"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-membrane adaptor activity","termid":"GO:0043495"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01745":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0030674"},{"rel_name":"is_a","termid":"GO:0060090"}],"interesting_parent_ids":["GO:0060090","GO:0003674","GO:0030674"],"is_obsolete":false,"name":"centromere-nuclear envelope anchor activity","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"centromere nuclear envelope anchor activity","type":"exact"},{"name":"centromere nuclear envelope tether activity","type":"exact"},{"name":"centromere-inner nuclear envelope anchor activity","type":"exact"},{"name":"centromere-inner nuclear envelope tether activity","type":"exact"},{"name":"chromosome, centromeric region-nuclear envelope anchor activity","type":"exact"},{"name":"nuclear envelope-centromere anchor activity","type":"exact"},{"name":"nuclear envelope-centromere tether activity","type":"exact"}],"termid":"GO:0140449","terms_by_termid":{"GO:0140449":null}}


id: MONDO:0001350
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A malignant neoplasm involving the parametrium.","direct_ancestors":[{"relation_name":"is_a","term_name":"broad ligament malignant neoplasm","termid":"MONDO:0001108"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"parametrium malignant neoplasm","secondary_identifiers":["ICD9:183.4","SCTID:448674007","UMLS:C0153581","DOID:11746","ICD10CM:C57.3","MEDGEN:509332"],"synonyms":[{"name":"cancer of parametrium","type":"exact"},{"name":"malignant neoplasm of parametrium","type":"exact"},{"name":"malignant parametrium neoplasm","type":"exact"},{"name":"parametrium cancer","type":"exact"}],"termid":"MONDO:0001350","xrefs":{"Monarch":{"xref_id":"0001350"}}}


id: GO:0051906
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process in which a pigment granule is maintained in a location and prevented from moving elsewhere.","definition_xrefs":["GOC:dph","GOC:ai","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"maintenance of vesicle location","termid":"GO:0051655"},{"relation_name":"part_of","term_name":"pigment granule localization","termid":"GO:0051875"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0051179"],"is_obsolete":false,"name":"maintenance of pigment granule location","synonyms":[{"name":"maintenance of pigment granule localization","type":"related"}],"termid":"GO:0051906"}


id: PBO:0044152
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CTDNEP1 pseudogene 1","termid":"PBO:0044152"}


id: GO:2000309
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production.","definition_xrefs":["GOC:mah","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of tumor necrosis factor superfamily cytokine production","termid":"GO:1903557"},{"relation_name":"is_a","term_name":"regulation of tumor necrosis factor (ligand) superfamily member 11 production","termid":"GO:2000307"},{"relation_name":"positively_regulates","term_name":"tumor necrosis factor (ligand) superfamily member 11 production","termid":"GO:0072535"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0010467"},{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"positive regulation of tumor necrosis factor (ligand) superfamily member 11 production","synonyms":[{"name":"positive regulation of RANKL production","type":"exact"},{"name":"positive regulation of TNFSF11 production","type":"exact"}],"termid":"GO:2000309"}


id: PBO:0028445
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_protein_localization_to_mitotic_spindle_midzone_during_anaphase_B","termid":"PBO:0028445"}


id: MONDO:0957097
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hemolytic-uremic syndrome","termid":"MONDO:0001549"},{"relation_name":"is_a","term_name":"inherited blood coagulation disorder","termid":"MONDO:0021181"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"hereditary hemolytic uremic syndrome","secondary_identifiers":["OMIMPS:235400","GARD:22330","MEDGEN:1825935","UMLS:C5680355","Orphanet:576742"],"synonyms":[{"name":"genetic hemolytic uremic syndrome","type":"exact"}],"termid":"MONDO:0957097","xrefs":{"Monarch":{"xref_id":"0957097"}}}


id: GO:0042359
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).","definition_xrefs":["ISBN:0471331309","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"fat-soluble vitamin metabolic process","termid":"GO:0006775"},{"relation_name":"is_a","term_name":"steroid metabolic process","termid":"GO:0008202"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0006766"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0006629","GO:0006766","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"vitamin D metabolic process","secondary_identifiers":["Reactome:R-HSA-196791"],"synonyms":[{"name":"calciferol metabolic process","type":"narrow"},{"name":"calciferol metabolism","type":"narrow"},{"name":"cholecalciferol metabolic process","type":"narrow"},{"name":"cholecalciferol metabolism","type":"narrow"},{"name":"ergocalciferol metabolic process","type":"narrow"},{"name":"ergocalciferol metabolism","type":"narrow"},{"name":"vitamin D metabolism","type":"exact"}],"termid":"GO:0042359"}


id: MONDO:0011561
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An Alzheimer's disease that is characterized by an associated with variation in the region 10q24.","definition_xrefs":["PMID:16385451","DOID:0110038"],"direct_ancestors":[{"relation_name":"is_a","term_name":"early-onset autosomal dominant Alzheimer disease","termid":"MONDO:0015140"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0002039"},{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0002039","MONDO:0000426","MONDO:0005559"],"is_obsolete":false,"name":"Alzheimer disease 6","secondary_identifiers":["MEDGEN:381362","UMLS:C1854187","MESH:C565325","GARD:16509","OMIM:605526"],"synonyms":[{"name":"AD6","type":"exact"},{"name":"Alzheimer disease 6","type":"exact"},{"name":"Alzheimer disease 6, late onset","type":"exact"},{"name":"Alzheimer disease 6, late-onset","type":"related"},{"name":"Alzheimer disease type 6","type":"exact"},{"name":"Alzheimer's disease 6","type":"exact"},{"name":"Alzheimer's disease type 6","type":"exact"},{"name":"plasma Beta-amyloid-42 level quantitative trait locus","type":"related"}],"termid":"MONDO:0011561","xrefs":{"Monarch":{"xref_id":"0011561"}}}


id: PBO:0030550
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_histidine_import","termid":"PBO:0030550"}


id: GO:1903893
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the ATF6-mediated unfolded protein response.","definition_xrefs":["GOC:bf","GOC:TermGenie","GO_REF:0000058","GOC:PARL","PMID:22013210"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of endoplasmic reticulum unfolded protein response","termid":"GO:1900103"},{"relation_name":"is_a","term_name":"regulation of ATF6-mediated unfolded protein response","termid":"GO:1903891"},{"relation_name":"positively_regulates","term_name":"ATF6-mediated unfolded protein response","termid":"GO:0036500"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"positive regulation of ATF6-mediated unfolded protein response","synonyms":[{"name":"activation of ATF6 branch of UPR","type":"narrow"},{"name":"activation of ATF6 signaling in response to endoplasmic reticulum stress","type":"related"},{"name":"activation of ATF6-alpha UPR branch","type":"narrow"},{"name":"activation of ATF6-beta UPR branch","type":"narrow"},{"name":"activation of ATF6-mediated unfolded protein response","type":"narrow"},{"name":"activation of UPR signaling by ATF6 stress sensor","type":"narrow"},{"name":"activation of activating transcription factor 6 signaling in unfolded protein response","type":"narrow"},{"name":"activation of endoplasmic reticulum unfolded protein response; ATF6 signaling","type":"narrow"},{"name":"positive regulation of ATF6 branch of UPR","type":"exact"},{"name":"positive regulation of ATF6 signaling in response to endoplasmic reticulum stress","type":"related"},{"name":"positive regulation of ATF6-alpha UPR branch","type":"narrow"},{"name":"positive regulation of ATF6-beta UPR branch","type":"narrow"},{"name":"positive regulation of UPR signaling by ATF6 stress sensor","type":"exact"},{"name":"positive regulation of activating transcription factor 6 signaling in unfolded protein response","type":"exact"},{"name":"positive regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling","type":"exact"},{"name":"up regulation of ATF6 branch of UPR","type":"exact"},{"name":"up regulation of ATF6 signaling in response to endoplasmic reticulum stress","type":"related"},{"name":"up regulation of ATF6-alpha UPR branch","type":"narrow"},{"name":"up regulation of ATF6-beta UPR branch","type":"narrow"},{"name":"up regulation of ATF6-mediated unfolded protein response","type":"exact"},{"name":"up regulation of UPR signaling by ATF6 stress sensor","type":"exact"},{"name":"up regulation of activating transcription factor 6 signaling in unfolded protein response","type":"exact"},{"name":"up regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling","type":"exact"},{"name":"up-regulation of ATF6 branch of UPR","type":"exact"},{"name":"up-regulation of ATF6 signaling in response to endoplasmic reticulum stress","type":"related"},{"name":"up-regulation of ATF6-alpha UPR branch","type":"narrow"},{"name":"up-regulation of ATF6-beta UPR branch","type":"narrow"},{"name":"up-regulation of ATF6-mediated unfolded protein response","type":"exact"},{"name":"up-regulation of UPR signaling by ATF6 stress sensor","type":"exact"},{"name":"up-regulation of activating transcription factor 6 signaling in unfolded protein response","type":"exact"},{"name":"up-regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling","type":"exact"},{"name":"upregulation of ATF6 branch of UPR","type":"exact"},{"name":"upregulation of ATF6 signaling in response to endoplasmic reticulum stress","type":"related"},{"name":"upregulation of ATF6-alpha UPR branch","type":"narrow"},{"name":"upregulation of ATF6-beta UPR branch","type":"narrow"},{"name":"upregulation of ATF6-mediated unfolded protein response","type":"exact"},{"name":"upregulation of UPR signaling by ATF6 stress sensor","type":"exact"},{"name":"upregulation of activating transcription factor 6 signaling in unfolded protein response","type":"exact"},{"name":"upregulation of endoplasmic reticulum unfolded protein response; ATF6 signaling","type":"exact"}],"termid":"GO:1903893"}


id: MONDO:0005607
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A type of chronic obstructive pulmonary disease characterized by chronic inflammation in the bronchial tree that results in edema, mucus production, obstruction, and reduced airflow to and from the lung alveoli. The most common cause is tobacco smoking. Signs and symptoms include coughing with excessive mucus production, and shortness of breath.","definition_xrefs":["NCIT:C26722"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bronchitis","termid":"MONDO:0003781"},{"relation_name":"is_a","term_name":"chronic obstructive pulmonary disease","termid":"MONDO:0005002"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chronic bronchitis","secondary_identifiers":["icd11.foundation:290835130","ICD9:491.9","ICD9:491.8","MEDGEN:3084","UMLS:C0008677","EFO:0006505","ICD9:491","MESH:D029481","SCTID:63480004"],"synonyms":[{"name":"bronchitis, chronic","type":"exact"}],"termid":"MONDO:0005607","xrefs":{"Monarch":{"xref_id":"0005607"}}}


id: PBO:0061316
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nuclear pore complex interacting protein family member A1","termid":"PBO:0061316"}


id: PBO:0078280
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Cys (anticodon GCA) 13-1","termid":"PBO:0078280"}


id: PBO:0073177
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"selenoprotein I","termid":"PBO:0073177"}


id: GO:0000411
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process involving galactose that activates or increases the rate of transcription.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of transcription by galactose","termid":"GO:0000409"},{"relation_name":"is_a","term_name":"carbon catabolite activation of transcription","termid":"GO:0045991"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006351"},{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006355"},{"rel_name":"positively_regulates","termid":"GO:0006351"}],"interesting_parent_ids":["GO:0006355","GO:0006351","GO:0010467","GO:0008150"],"is_obsolete":false,"name":"positive regulation of transcription by galactose","synonyms":[{"name":"activation of transcription by galactose","type":"narrow"},{"name":"stimulation of transcription by galactose","type":"narrow"},{"name":"up regulation of transcription by galactose","type":"exact"},{"name":"up-regulation of transcription by galactose","type":"exact"},{"name":"upregulation of transcription by galactose","type":"exact"}],"termid":"GO:0000411"}


id: GO:0008195
data:
  {"annotated_genes":["SJAG_02763","SJAG_02356","SJAG_00920"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[73114,77845,78745],"is_not":false,"summary":null,"term":"GO:0008195"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: a 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate.","definition_xrefs":["PMID:25814022","GOC:pr","RHEA:27429"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lipid phosphatase activity","termid":"GO:0042577"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00920":null,"SJAG_02356":null,"SJAG_02763":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016788","GO:0003824","GO:0016787","GO:0003674"],"is_obsolete":false,"name":"phosphatidate phosphatase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["EC:3.1.3.4","Reactome:R-HSA-1483203","Reactome:R-HSA-163688","MetaCyc:PHOSPHATIDATE-PHOSPHATASE-RXN","Reactome:R-HSA-164056","Reactome:R-HSA-2029468","GO:0004606","Reactome:R-HSA-390329","Reactome:R-HSA-5221130","Reactome:R-HSA-6797630","Reactome:R-HSA-75899"],"synonyms":[{"name":"3-sn-phosphatidate phosphohydrolase activity","type":"related"},{"name":"acid phosphatidyl phosphatase activity","type":"related"},{"name":"phosphatic acid phosphatase activity","type":"related"},{"name":"phosphatic acid phosphohydrolase activity","type":"related"},{"name":"phosphatidate phosphohydrolase activity","type":"exact"},{"name":"phosphatidic acid phosphatase activity","type":"related"}],"termid":"GO:0008195","terms_by_termid":{"GO:0008195":null}}


id: GO:1901303
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of cargo loading into a COPII-coated vesicle.","definition_xrefs":["PMID:15899885","GOC:lb","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of intracellular transport","termid":"GO:0032387"},{"relation_name":"is_a","term_name":"regulation of cargo loading into COPII-coated vesicle","termid":"GO:1901301"},{"relation_name":"negatively_regulates","term_name":"COPII-coated vesicle cargo loading","termid":"GO:0090110"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810"],"is_obsolete":false,"name":"negative regulation of cargo loading into COPII-coated vesicle","synonyms":[{"name":"down regulation of COPII coat-cargo complex assembly","type":"related"},{"name":"down regulation of cargo loading into COPII vesicle","type":"exact"},{"name":"down regulation of cargo loading into COPII-coated vesicle","type":"exact"},{"name":"down regulation of cargo selection into COPII-coated vesicle","type":"exact"},{"name":"down-regulation of COPII coat-cargo complex assembly","type":"related"},{"name":"down-regulation of cargo loading into COPII vesicle","type":"exact"},{"name":"down-regulation of cargo loading into COPII-coated vesicle","type":"exact"},{"name":"down-regulation of cargo selection into COPII-coated vesicle","type":"exact"},{"name":"downregulation of COPII coat-cargo complex assembly","type":"related"},{"name":"downregulation of cargo loading into COPII vesicle","type":"exact"},{"name":"downregulation of cargo loading into COPII-coated vesicle","type":"exact"},{"name":"downregulation of cargo selection into COPII-coated vesicle","type":"exact"},{"name":"inhibition of COPII coat-cargo complex assembly","type":"related"},{"name":"inhibition of COPII vesicle protein binding","type":"narrow"},{"name":"inhibition of cargo loading into COPII vesicle","type":"exact"},{"name":"inhibition of cargo loading into COPII-coated vesicle","type":"narrow"},{"name":"inhibition of cargo selection into COPII-coated vesicle","type":"exact"},{"name":"inhibition of protein sorting into COPII-coated vesicles","type":"exact"},{"name":"negative regulation of COPII coat-cargo complex assembly","type":"related"},{"name":"negative regulation of cargo loading into COPII vesicle","type":"exact"},{"name":"negative regulation of cargo selection into COPII-coated vesicle","type":"exact"}],"termid":"GO:1901303"}


id: GO:1904246
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of polynucleotide adenylyltransferase activity.","definition_xrefs":["GOC:TermGenie","GO_REF:0000059","GOC:kmv","PMID:19460348"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of transferase activity","termid":"GO:0051348"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of polynucleotide adenylyltransferase activity","synonyms":[{"name":"down regulation of AMP polynucleotidylexotransferase activity","type":"exact"},{"name":"down regulation of ATP-polynucleotide adenylyltransferase activity","type":"exact"},{"name":"down regulation of ATP:polynucleotide adenylyltransferase activity","type":"exact"},{"name":"down regulation of ATP:polynucleotidylexotransferase activity","type":"exact"},{"name":"down regulation of NTP polymerase activity","type":"exact"},{"name":"down regulation of RNA adenylating enzyme activity","type":"exact"},{"name":"down regulation of RNA formation factors, PF1","type":"related"},{"name":"down regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity","type":"exact"},{"name":"down regulation of poly(A) hydrolase activity","type":"exact"},{"name":"down regulation of poly(A) polymerase activity","type":"exact"},{"name":"down regulation of poly(A) synthetase activity","type":"exact"},{"name":"down regulation of poly-A polymerase activity","type":"exact"},{"name":"down regulation of polyadenylate nucleotidyltransferase activity","type":"exact"},{"name":"down regulation of polyadenylate polymerase activity","type":"exact"},{"name":"down regulation of polyadenylate synthetase activity","type":"exact"},{"name":"down regulation of polyadenylic acid polymerase activity","type":"exact"},{"name":"down regulation of polyadenylic polymerase activity","type":"exact"},{"name":"down regulation of polynucleotide adenylyltransferase activity","type":"exact"},{"name":"down regulation of terminal riboadenylate transferase activity","type":"exact"},{"name":"down-regulation of AMP polynucleotidylexotransferase activity","type":"exact"},{"name":"down-regulation of ATP-polynucleotide adenylyltransferase activity","type":"exact"},{"name":"down-regulation of ATP:polynucleotide adenylyltransferase activity","type":"exact"},{"name":"down-regulation of ATP:polynucleotidylexotransferase activity","type":"exact"},{"name":"down-regulation of NTP polymerase activity","type":"exact"},{"name":"down-regulation of RNA adenylating enzyme activity","type":"exact"},{"name":"down-regulation of RNA formation factors, PF1","type":"related"},{"name":"down-regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity","type":"exact"},{"name":"down-regulation of poly(A) hydrolase activity","type":"exact"},{"name":"down-regulation of poly(A) polymerase activity","type":"exact"},{"name":"down-regulation of poly(A) synthetase activity","type":"exact"},{"name":"down-regulation of poly-A polymerase activity","type":"exact"},{"name":"down-regulation of polyadenylate nucleotidyltransferase activity","type":"exact"},{"name":"down-regulation of polyadenylate polymerase activity","type":"exact"},{"name":"down-regulation of polyadenylate synthetase activity","type":"exact"},{"name":"down-regulation of polyadenylic acid polymerase activity","type":"exact"},{"name":"down-regulation of polyadenylic polymerase activity","type":"exact"},{"name":"down-regulation of polynucleotide adenylyltransferase activity","type":"exact"},{"name":"down-regulation of terminal riboadenylate transferase activity","type":"exact"},{"name":"downregulation of AMP polynucleotidylexotransferase activity","type":"exact"},{"name":"downregulation of ATP-polynucleotide adenylyltransferase activity","type":"exact"},{"name":"downregulation of ATP:polynucleotide adenylyltransferase activity","type":"exact"},{"name":"downregulation of ATP:polynucleotidylexotransferase activity","type":"exact"},{"name":"downregulation of NTP polymerase activity","type":"exact"},{"name":"downregulation of RNA adenylating enzyme activity","type":"exact"},{"name":"downregulation of RNA formation factors, PF1","type":"related"},{"name":"downregulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity","type":"exact"},{"name":"downregulation of poly(A) hydrolase activity","type":"exact"},{"name":"downregulation of poly(A) polymerase activity","type":"exact"},{"name":"downregulation of poly(A) synthetase activity","type":"exact"},{"name":"downregulation of poly-A polymerase activity","type":"exact"},{"name":"downregulation of polyadenylate nucleotidyltransferase activity","type":"exact"},{"name":"downregulation of polyadenylate polymerase activity","type":"exact"},{"name":"downregulation of polyadenylate synthetase activity","type":"exact"},{"name":"downregulation of polyadenylic acid polymerase activity","type":"exact"},{"name":"downregulation of polyadenylic polymerase activity","type":"exact"},{"name":"downregulation of polynucleotide adenylyltransferase activity","type":"exact"},{"name":"downregulation of terminal riboadenylate transferase activity","type":"exact"},{"name":"inhibition of AMP polynucleotidylexotransferase activity","type":"narrow"},{"name":"inhibition of ATP-polynucleotide adenylyltransferase activity","type":"narrow"},{"name":"inhibition of ATP:polynucleotide adenylyltransferase activity","type":"narrow"},{"name":"inhibition of ATP:polynucleotidylexotransferase activity","type":"narrow"},{"name":"inhibition of NTP polymerase activity","type":"narrow"},{"name":"inhibition of RNA adenylating enzyme activity","type":"narrow"},{"name":"inhibition of RNA formation factors, PF1","type":"related"},{"name":"inhibition of adenosine triphosphate:ribonucleic acid adenylyltransferase activity","type":"narrow"},{"name":"inhibition of poly(A) hydrolase activity","type":"narrow"},{"name":"inhibition of poly(A) polymerase activity","type":"narrow"},{"name":"inhibition of poly(A) synthetase activity","type":"narrow"},{"name":"inhibition of poly-A polymerase activity","type":"narrow"},{"name":"inhibition of polyadenylate nucleotidyltransferase activity","type":"narrow"},{"name":"inhibition of polyadenylate polymerase activity","type":"narrow"},{"name":"inhibition of polyadenylate synthetase activity","type":"narrow"},{"name":"inhibition of polyadenylic acid polymerase activity","type":"narrow"},{"name":"inhibition of polyadenylic polymerase activity","type":"narrow"},{"name":"inhibition of polynucleotide adenylyltransferase activity","type":"narrow"},{"name":"inhibition of terminal riboadenylate transferase activity","type":"narrow"},{"name":"negative regulation of AMP polynucleotidylexotransferase activity","type":"exact"},{"name":"negative regulation of ATP-polynucleotide adenylyltransferase activity","type":"exact"},{"name":"negative regulation of ATP:polynucleotide adenylyltransferase activity","type":"exact"},{"name":"negative regulation of ATP:polynucleotidylexotransferase activity","type":"exact"},{"name":"negative regulation of NTP polymerase activity","type":"exact"},{"name":"negative regulation of RNA adenylating enzyme activity","type":"exact"},{"name":"negative regulation of RNA formation factors, PF1","type":"related"},{"name":"negative regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity","type":"exact"},{"name":"negative regulation of poly(A) hydrolase activity","type":"exact"},{"name":"negative regulation of poly(A) polymerase activity","type":"exact"},{"name":"negative regulation of poly(A) synthetase activity","type":"exact"},{"name":"negative regulation of poly-A polymerase activity","type":"exact"},{"name":"negative regulation of polyadenylate nucleotidyltransferase activity","type":"exact"},{"name":"negative regulation of polyadenylate polymerase activity","type":"exact"},{"name":"negative regulation of polyadenylate synthetase activity","type":"exact"},{"name":"negative regulation of polyadenylic acid polymerase activity","type":"exact"},{"name":"negative regulation of polyadenylic polymerase activity","type":"exact"},{"name":"negative regulation of terminal riboadenylate transferase activity","type":"exact"}],"termid":"GO:1904246"}


id: PBO:0028044
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_rate_of_cytoplasmic_microtubule_polymerization","termid":"PBO:0028044"}


id: GO:0072436
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The series of events in which information about whether DNA replication is complete is received and converted into a molecular signal, contributing to a DNA replication checkpoint.","definition_xrefs":["GOC:mtg_cell_cycle"],"gene_count":0,"genotype_count":0,"name":"obsolete detection of stimulus involved in DNA replication checkpoint (obsolete GO:0072436)","synonyms":[{"name":"DNA replication checkpoint sensor mechanism","type":"related"},{"name":"DNA replication checkpoint sensor process","type":"related"},{"name":"sensing involved in DNA replication checkpoint","type":"related"}],"termid":"GO:0072436"}


id: PBO:0004681
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcription elongation factor complex subunit Spt4","termid":"PBO:0004681"}


id: FYPO:0008162
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell cycle checkpoint phenotype in which the incidence of mitotic cell cycle arrest or delay due to regulation by the mitotic S-phase DNA damage checkpoint is greater than in wild type under any specified set of conditions.","definition_xrefs":["PMID:18344406"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal S-phase DNA damage checkpoint","termid":"FYPO:0000007"},{"relation_name":"is_a","term_name":"increased mitotic DNA damage checkpoint activation","termid":"FYPO:0001707"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000298"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0000631","FYPO:0000002","FYPO:0000298","FYPO:0001320","FYPO:0001985","FYPO:0005447"],"is_obsolete":false,"name":"increased activation of S-phase DNA damage checkpoint","termid":"FYPO:0008162"}


id: PBO:0111857
data:
  {"annotation_feature_type":"gene","cv_name":"pombase_family_or_domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SIN3 family co-repressor","termid":"PBO:0111857"}


id: FYPO:0004583
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which meiotic chromosome condensation is abnormal.","definition_xrefs":["PomBase:mah","PMID:23263988"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal chromosome condensation","termid":"FYPO:0000159"},{"relation_name":"is_a","term_name":"abnormal meiotic chromosome organization","termid":"FYPO:0006759"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000641"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000002","FYPO:0000631","FYPO:0000641","FYPO:0001985"],"is_obsolete":false,"name":"abnormal meiotic chromosome condensation","synonyms":[{"name":"abnormal chromosome condensation during meiosis I","type":"exact"},{"name":"abnormal chromosome condensation during meiotic cell cycle","type":"related"}],"termid":"FYPO:0004583"}


id: MONDO:0000535
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete tonsil squamous cell carcinoma (obsolete MONDO:0000535)","termid":"MONDO:0000535","xrefs":{"Monarch":{"xref_id":"0000535"}}}


id: PBO:0064179
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phospholipase A2 group XF, pseudogene","termid":"PBO:0064179"}


id: GO:0030057
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism.","definition_xrefs":["GOC:mah","ISBN:0815332181","GOC:mtg_muscle"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell-cell junction","termid":"GO:0005911"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"desmosome","secondary_identifiers":["Wikipedia:Desmosome"],"synonyms":[{"name":"macula adherens","type":"exact"},{"name":"spot desmosome","type":"exact"}],"termid":"GO:0030057"}


id: PBO:0071255
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L23a pseudogene 96","termid":"PBO:0071255"}


id: FYPO:0005624
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ultraviolet light during S phase of the mitotic cell cycle.","definition_xrefs":["PMID:26652183","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sensitive to UV during vegetative growth","termid":"FYPO:0000268"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000003"}],"interesting_parent_ids":["FYPO:0000003","FYPO:0005447","FYPO:0000139","FYPO:0001985"],"is_obsolete":false,"name":"sensitive to UV during mitotic S phase","synonyms":[{"name":"decreased growth during cellular response to UV during mitotic S phase","type":"exact"},{"name":"decreased vegetative cell population growth during cellular response to UV during mitotic S phase","type":"exact"},{"name":"hypersensitive to UV during mitotic S phase","type":"exact"},{"name":"increased sensitivity to UV irradiation during mitotic S phase","type":"exact"},{"name":"sensitive to UV during S phase during vegetative growth","type":"exact"},{"name":"sensitive to UV during S phase of mitotic cell cycle","type":"exact"},{"name":"sensitive to ultraviolet light during mitotic S phase","type":"exact"}],"termid":"FYPO:0005624"}


id: PBO:0043337
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CLN6 transmembrane ER protein","termid":"PBO:0043337"}


id: MONDO:0009713
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"myopia","termid":"MONDO:0001384"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"myopia 18, autosomal recessive","secondary_identifiers":["MEDGEN:411856","MESH:C567606","UMLS:C2749509","OMIM:255500"],"synonyms":[{"name":"MYP18","type":"exact"},{"name":"myopia 18, autosomal recessive","type":"exact"}],"termid":"MONDO:0009713","xrefs":{"Monarch":{"xref_id":"0009713"}}}


id: GO:0003033
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the aortic bodies.","definition_xrefs":["GOC:mtg_cardio"],"direct_ancestors":[{"relation_name":"is_a","term_name":"detection of hypoxic conditions in blood by chemoreceptor signaling","termid":"GO:0002007"},{"relation_name":"part_of","term_name":"regulation of systemic arterial blood pressure by aortic body chemoreceptor signaling","termid":"GO:0003028"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"detection of hypoxic conditions in blood by aortic body chemoreceptor signaling","synonyms":[{"name":"detection of hypoxic conditions in blood by aortic body chemoreceptor signalling","type":"exact"}],"termid":"GO:0003033"}


id: RO:0002462
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","direct_ancestors":[{"relation_name":"is_a","term_name":"partner_in","termid":"RO:0002461"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"subject_participant_in","termid":"RO:0002462"}


id: PBO:0044199
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cathepsin H","termid":"PBO:0044199"}


id: PBO:0004304
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kinesin-like protein Klp9","termid":"PBO:0004304"}


id: PBO:0048732
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glutamate dehydrogenase 1 pseudogene 3","termid":"PBO:0048732"}


id: PBO:0040965
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BCL2 interacting protein 3 pseudogene 36","termid":"PBO:0040965"}


id: MONDO:0011976
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Lipodystrophy-intellectual disability-deafness syndrome is an extremely rare form of genetic lipodystrophy, reported in 3 patients from one family to date, characterized by generalized congenital lipodystrophy, low birth weight, progressive sensorineural deafness occurring in childhood, intellectual deficit, progressive osteopenia, delayed skeletal maturation, skeletal abnormalities described as slender, undermineralized tubular bones, and dense metaphyseal striations in the distal femur, ulna and radius of older patients. Autosomal recessive inheritance has been suggested.","definition_xrefs":["Orphanet:50811"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"progeroid syndrome","termid":"MONDO:0015333"},{"relation_name":"excluded_subClassOf","term_name":"obsolete primary bone dysplasia with defective bone mineralization (obsolete MONDO:0019705)","termid":"MONDO:0019705"},{"relation_name":"is_a","term_name":"hereditary lipodystrophy","termid":"MONDO:0020087"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0005093"],"is_obsolete":false,"name":"lipodystrophy-intellectual disability-deafness syndrome","secondary_identifiers":["UMLS:C1842465","MEDGEN:334166","OMIM:608154","GARD:16646","MESH:C564283","SCTID:721973006"],"synonyms":[{"name":"Rajab-Spranger syndrome","type":"exact"},{"name":"lipodystrophy, generalized, with intellectual disability, deafness, short stature, and slender bones","type":"related"},{"name":"lipodystrophy, generalized, with mental retardation, deafness, short stature, and slender bones","type":"related"}],"termid":"MONDO:0011976","xrefs":{"Monarch":{"xref_id":"0011976"}}}


id: PBO:0001913
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Pombe iNhibitor of Growth","termid":"PBO:0001913"}


id: FYPO:0003507
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing zinc ions.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal vegetative cell population growth","termid":"FYPO:0001357"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0002058"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0000139","FYPO:0002060","FYPO:0000003","FYPO:0002057","FYPO:0002058"],"is_obsolete":false,"name":"normal growth on zinc","synonyms":[{"name":"normal cell population growth in presence of zinc","type":"exact"},{"name":"normal cell population growth on zinc","type":"exact"},{"name":"normal cell population growth on zinc ion","type":"exact"},{"name":"normal cellular response to zinc","type":"related"},{"name":"normal growth on zinc ions","type":"exact"},{"name":"normal vegetative cell population growth on zinc","type":"exact"}],"termid":"FYPO:0003507"}


id: GO:0004852
data:
  {"annotated_genes":["SJAG_05283"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[76668],"is_not":false,"summary":null,"term":"GO:0004852"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: hydroxymethylbilane = H2O + uroporphyrinogen III.","definition_xrefs":["RHEA:18965","EC:4.2.1.75"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydro-lyase activity","termid":"GO:0016836"}],"gene_count":1,"genes_by_uniquename":{"SJAG_05283":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016829"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016829"],"is_obsolete":false,"name":"uroporphyrinogen-III synthase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["KEGG_REACTION:R03165","Reactome:R-HSA-189488","MetaCyc:UROGENIIISYN-RXN"],"synonyms":[{"name":"URO-synthase activity","type":"related"},{"name":"hydroxymethylbilane hydro-lyase (cyclizing) activity","type":"related"},{"name":"hydroxymethylbilane hydro-lyase (cyclizing; uroporphyrinogen-III-forming)","type":"related"},{"name":"porphobilinogenase activity","type":"related"},{"name":"uroporphyrinogen III cosynthase activity","type":"related"},{"name":"uroporphyrinogen isomerase activity","type":"related"},{"name":"uroporphyrinogen-III cosynthase activity","type":"related"},{"name":"uroporphyrinogen-III cosynthetase activity","type":"related"}],"termid":"GO:0004852","terms_by_termid":{"GO:0004852":null}}


id: GO:1902357
data:
  {"annotated_genes":["SJAG_00671"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[90227],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990556"}]},"cv_name":"biological_process","definition":"The process in which 2-isopropylmalate(2-) is transported across a membrane.","definition_xrefs":["GOC:dph","GOC:vw","PMID:18682385","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"isopropylmalate transport","termid":"GO:0034659"},{"relation_name":"is_a","term_name":"carboxylic acid transmembrane transport","termid":"GO:1905039"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00671":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0051179","GO:0055085","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"2-isopropylmalate(2-) transmembrane transport","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:1902357","terms_by_termid":{"GO:1990556":null}}


id: RO:HOM0000005
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"Homoplasy that involves homologous underlying mechanisms or structures.","direct_ancestors":[{"relation_name":"is_a","term_name":"in_homoplasy_relationship_with","termid":"RO:HOM0000002"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"in_parallelism_relationship_with","synonyms":[{"name":"parallel evolution","type":"exact"}],"termid":"RO:HOM0000005"}


id: GO:1903111
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of single-strand break repair via homologous recombination.","definition_xrefs":["PMID:24339919","GO_REF:0000058","GOC:bhm","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of DNA recombination","termid":"GO:0045910"},{"relation_name":"is_a","term_name":"regulation of single-strand break repair via homologous recombination","termid":"GO:1903110"},{"relation_name":"is_a","term_name":"negative regulation of single strand break repair","termid":"GO:1903517"},{"relation_name":"negatively_regulates","term_name":"single-strand break repair via homologous recombination","termid":"GO:1990396"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0006310"},{"rel_name":"regulates","termid":"GO:0006310"},{"rel_name":"negatively_regulates","termid":"GO:0006259"},{"rel_name":"regulates","termid":"GO:0006281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0006281"},{"rel_name":"regulates","termid":"GO:0006259"}],"interesting_parent_ids":["GO:0006310","GO:0006259","GO:0008150","GO:0006281"],"is_obsolete":false,"name":"negative regulation of single-strand break repair via homologous recombination","synonyms":[{"name":"down regulation of single-strand break repair via homologous recombination","type":"exact"},{"name":"down-regulation of single-strand break repair via homologous recombination","type":"exact"},{"name":"downregulation of single-strand break repair via homologous recombination","type":"exact"},{"name":"inhibition of single-strand break repair via homologous recombination","type":"narrow"}],"termid":"GO:1903111"}


id: SO:0002233
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A chromosomal locus where complementary lncRNA and associated proteins accumulate at the corresponding lncRNA gene loci to tether homologous chromosome during chromosome pairing at meiosis I.","definition_xrefs":["PMID:31811152","PMID:22582262"],"direct_ancestors":[{"relation_name":"is_a","term_name":"binding_site","termid":"SO:0000409"},{"relation_name":"member_of","term_name":"chromosome_part","termid":"SO:0000830"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"homologous_chromosome_recognition_and_pairing_locus","synonyms":[{"name":"homologous chromosome recognition and pairing locus","type":"exact"}],"termid":"SO:0002233"}


id: PR:O60114
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- dhx29 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O60114"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized helicase C15C4.05 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC15C4.05","synonyms":[{"name":"Spom972h-dhx29","type":"exact"}],"termid":"PR:O60114"}


id: FYPO:0002970
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is increased during metaphase.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased protein localization to mitotic spindle pole body","termid":"FYPO:0002969"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000002","FYPO:0001985","FYPO:0000138","FYPO:0001320"],"is_obsolete":false,"name":"increased protein localization to mitotic spindle pole body during metaphase","synonyms":[{"name":"increased protein localisation to mitotic spindle pole body during metaphase","type":"exact"},{"name":"increased protein localization to mitotic SPB during metaphase","type":"exact"},{"name":"increased protein localization to mitotic spindle pole body during mitotic metaphase","type":"exact"},{"name":"increased protein localization to spindle pole body during metaphase during vegetative growth","type":"exact"}],"termid":"FYPO:0002970"}


id: PBO:0073474
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sarcoglycan epsilon","termid":"PBO:0073474"}


id: PBO:0003796
data:
  {"annotation_feature_type":"gene","cv_name":"disease_associated","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Chediak-Higashi syndrome","termid":"PBO:0003796"}


id: GO:0002097
data:
  {"annotated_genes":["SJAG_03896","SJAG_04380","SJAG_05023","SJAG_00683","SJAG_03677","SJAG_02179","SJAG_04189","SJAG_03616","SJAG_04452","SJAG_05249","SJAG_01024","SJAG_03932","SJAG_04113","SJAG_00579","SJAG_01418","SJAG_00235","SJAG_06284","SJAG_02302","SJAG_00352","SJAG_00358","SJAG_02099","SJAG_04175","SJAG_01877","SJAG_04367","SJAG_01302","SJAG_04756","SJAG_04704","SJAG_01781","SJAG_00186"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[96075,108714],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990799"},{"annotations":[77965,94609],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070899"},{"annotations":[59505,102929,75550],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0002100"},{"annotations":[74067,112000,81515,120657,115829,102393],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0002926"},{"annotations":[90077,95739],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0002127"},{"annotations":[74120],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0002101"},{"annotations":[97608,100399,100400,91495],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0002099"},{"annotations":[118823,75813,119062,79276,75934],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0002143"},{"annotations":[107381,97875,120525,89605],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0002098"}]},"cv_name":"biological_process","definition":"The process in which the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally modified.","definition_xrefs":["ISBN:155581073X","GOC:hjd"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tRNA modification","termid":"GO:0006400"}],"gene_count":29,"genes_by_uniquename":{"SJAG_00186":null,"SJAG_00235":null,"SJAG_00352":null,"SJAG_00358":null,"SJAG_00579":null,"SJAG_00683":null,"SJAG_01024":null,"SJAG_01302":null,"SJAG_01418":null,"SJAG_01781":null,"SJAG_01877":null,"SJAG_02099":null,"SJAG_02179":null,"SJAG_02302":null,"SJAG_03616":null,"SJAG_03677":null,"SJAG_03896":null,"SJAG_03932":null,"SJAG_04113":null,"SJAG_04175":null,"SJAG_04189":null,"SJAG_04367":null,"SJAG_04380":null,"SJAG_04452":null,"SJAG_04704":null,"SJAG_04756":null,"SJAG_05023":null,"SJAG_05249":null,"SJAG_06284":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006399"}],"interesting_parent_ids":["GO:0010467","GO:0008150","GO:0006399"],"is_obsolete":false,"name":"tRNA wobble base modification","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0002097","terms_by_termid":{"GO:0002098":null,"GO:0002099":null,"GO:0002100":null,"GO:0002101":null,"GO:0002127":null,"GO:0002143":null,"GO:0002926":null,"GO:0070899":null,"GO:1990799":null}}


id: PBO:0082230
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching","termid":"PBO:0082230"}


id: PBO:0058837
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 8067","termid":"PBO:0058837"}


id: GO:0051348
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of catalytic activity","termid":"GO:0043086"},{"relation_name":"is_a","term_name":"regulation of transferase activity","termid":"GO:0051338"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of transferase activity","synonyms":[{"name":"down regulation of transferase activity","type":"exact"},{"name":"down-regulation of transferase activity","type":"exact"},{"name":"downregulation of transferase activity","type":"exact"},{"name":"inhibition of transferase activity","type":"narrow"},{"name":"transferase inhibitor","type":"exact"}],"termid":"GO:0051348"}


id: PBO:0000220
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Septum Initiation Defective","termid":"PBO:0000220"}


id: MONDO:0020641
data:
  {"annotated_genes":["SJAG_00229","SJAG_03689","SJAG_03453","SJAG_04114"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88600,89153,88601],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008903"},{"annotations":[88138],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011014"}]},"cv_name":"mondo","definition":"A benign or malignant, primary or metastatic neoplasm involving the respiratory tract.","definition_xrefs":["NCIT:C3355"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neoplasm","termid":"MONDO:0005070"},{"relation_name":"is_a","term_name":"respiratory system disorder","termid":"MONDO:0005087"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00229":null,"SJAG_03453":null,"SJAG_03689":null,"SJAG_04114":null},"genotype_count":0,"is_obsolete":false,"name":"respiratory tract neoplasm","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["SCTID:126667002","UMLS:C0035244","EFO:0003853","ICD10CM:C30-C39","MEDGEN:11200","MESH:D012142"],"synonyms":[{"name":"neoplasm of respiratory tract","type":"exact"},{"name":"neoplasm of the respiratory tract","type":"exact"},{"name":"neoplasm, respiratory tract","type":"exact"},{"name":"neoplasms, respiratory tract","type":"exact"},{"name":"respiratory system neoplasm","type":"exact"},{"name":"respiratory tract neoplasm","type":"exact"},{"name":"respiratory tract tumor","type":"exact"},{"name":"respiratory tract tumour","type":"exact"},{"name":"tract neoplasm, respiratory","type":"exact"},{"name":"tract neoplasms, respiratory","type":"exact"},{"name":"tumor of respiratory tract","type":"exact"},{"name":"tumor of the respiratory tract","type":"exact"},{"name":"tumour of respiratory tract","type":"exact"},{"name":"tumour of the respiratory tract","type":"exact"}],"termid":"MONDO:0020641","terms_by_termid":{"MONDO:0008903":null,"MONDO:0011014":null},"xrefs":{"Monarch":{"xref_id":"0020641"}}}


id: GO:1903510
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways involving mucopolysaccharide.","definition_xrefs":["PMID:4236091","GOC:TermGenie","GOC:dph","GO_REF:0000068"],"gene_count":0,"genotype_count":0,"name":"obsolete mucopolysaccharide metabolic process (obsolete GO:1903510)","synonyms":[{"name":"mucopolysaccharide metabolism","type":"exact"}],"termid":"GO:1903510"}


id: PBO:0074780
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, C/D box 3 pseudogene 3","termid":"PBO:0074780"}


id: PBO:0042848
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cilia and flagella associated protein 57","termid":"PBO:0042848"}


id: GO:0047478
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-aspartate + ATP + NH4 = L-asparagine + ADP + 2 H+ + phosphate.","definition_xrefs":["EC:6.3.1.4","RHEA:14197"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acid-ammonia (or amide) ligase activity","termid":"GO:0016880"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016874"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016874"],"is_obsolete":false,"name":"aspartate-ammonia ligase (ADP-forming) activity","secondary_identifiers":["KEGG_REACTION:R00482","MetaCyc:6.3.1.4-RXN"],"synonyms":[{"name":"L-aspartate:ammonia ligase (ADP-forming)","type":"related"},{"name":"asparagine synthetase (ADP-forming) activity","type":"related"},{"name":"asparagine synthetase (adenosine diphosphate-forming)","type":"related"}],"termid":"GO:0047478"}


id: PBO:0090174
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rab GEF, implicated in endosomal transport","termid":"PBO:0090174"}


id: PATO:0000969
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A size quality inhering in a bearer by virtue of the bearer's being abnormally small.","definition_xrefs":["Answers.com:Answers.com"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased size","termid":"PATO:0000587"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dwarf-like","synonyms":[{"name":"dwarfed","type":"exact"}],"termid":"PATO:0000969"}


id: PBO:0057557
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 675","termid":"PBO:0057557"}


id: PBO:0072483
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein SA pseudogene 12","termid":"PBO:0072483"}


id: PBO:0110061
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nifs homolog, possible cysteine desulfurase, implicated in iron-sulfur cluster assembly","termid":"PBO:0110061"}


id: PBO:0029873
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_histone_H4_acetylation","termid":"PBO:0029873"}


id: GO:0045132
data:
  {"annotated_genes":["SJAG_05226","SJAG_03217","SJAG_01082","SJAG_03926","SJAG_03327","SJAG_01837","SJAG_05260","SJAG_00727","SJAG_01805","SJAG_03287","SJAG_05295","SJAG_02761","SJAG_03680","SJAG_02731","SJAG_01538","SJAG_03698","SJAG_00794","SJAG_07002","SJAG_01263","SJAG_01546","SJAG_05266","SJAG_04950","SJAG_03942","SJAG_01371","SJAG_03540","SJAG_02624","SJAG_03681","SJAG_02814","SJAG_03989","SJAG_04457","SJAG_02606","SJAG_04143","SJAG_00207","SJAG_00600","SJAG_00229","SJAG_03092","SJAG_05196","SJAG_01211","SJAG_04623","SJAG_03683","SJAG_05220","SJAG_01873","SJAG_01601","SJAG_00646","SJAG_03048","SJAG_03437","SJAG_01067","SJAG_04259","SJAG_03220","SJAG_01278","SJAG_02104","SJAG_05319","SJAG_01777","SJAG_00678","SJAG_05019","SJAG_04076","SJAG_02542","SJAG_04745","SJAG_00918","SJAG_02346","SJAG_00756","SJAG_01613","SJAG_02286","SJAG_01224","SJAG_04508","SJAG_04126","SJAG_03073","SJAG_03685","SJAG_00418","SJAG_01775"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[89683,95642],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0051456"},{"annotations":[115642,95606,109656,118925,100432,89626,103155,117399,92098],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0031619"},{"annotations":[89572,80574,109657,113077,112401],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0007129"},{"annotations":[62362,91175,61538,118726],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0045143"},{"annotations":[91409,118926],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0030999"},{"annotations":[65551,91579],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0070197"},{"annotations":[106934,89209,91580,101742,104640],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0032121"},{"annotations":[102198,110983,70177,101034,104255,66730,117784,97129,95609],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:1990571"},{"annotations":[95610,115643,106321,109658,116357,117761,103614,115083,100935,103089],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:1990813"},{"annotations":[72488],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0051307"},{"annotations":[95693,112028],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0051755"},{"annotations":[115084,113537,89818],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0045144"},{"annotations":[98581,96588],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0090306"},{"annotations":[103256],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0051232"},{"annotations":[103257,101036],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0140642"},{"annotations":[117803,119560,119422,98529],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0045141"},{"annotations":[115844],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0044821"},{"annotations":[112031,95698],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0090006"},{"annotations":[104210],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0062123"},{"annotations":[118542],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:1904967"},{"annotations":[109342,111739,90958,112207,117786,118779,115086,110729,92794,91564,102342,97130,104257,95623,107303,110986,97376,100440,103159,109660,99718,112163,115956],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0051455"}]},"cv_name":"biological_process","definition":"The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle.","definition_xrefs":["GOC:ai","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nuclear chromosome segregation","termid":"GO:0098813"},{"relation_name":"is_a","term_name":"meiotic cell cycle process","termid":"GO:1903046"},{"relation_name":"part_of","term_name":"meiotic nuclear 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chromosome segregation","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null,"GO_REF:0000117":null},"termid":"GO:0045132","terms_by_termid":{"GO:0007129":null,"GO:0030999":null,"GO:0031619":null,"GO:0032121":null,"GO:0044821":null,"GO:0045141":null,"GO:0045143":null,"GO:0045144":null,"GO:0051232":null,"GO:0051307":null,"GO:0051455":null,"GO:0051456":null,"GO:0051755":null,"GO:0062123":null,"GO:0070197":null,"GO:0090006":null,"GO:0090306":null,"GO:0140642":null,"GO:1904967":null,"GO:1990571":null,"GO:1990813":null}}


id: PR:Q09752
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- fnx1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q09752"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"multidrug resistance protein fnx1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC12C2.13c","synonyms":[{"name":"Spom972h-fnx1","type":"exact"}],"termid":"PR:Q09752"}


id: MONDO:0004110
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hairy cell leukemia that is resistant to treatment.","definition_xrefs":["NCIT:C8030"],"direct_ancestors":[{"relation_name":"is_a","term_name":"refractory hematologic cancer","termid":"MONDO:0004111"},{"relation_name":"is_a","term_name":"hairy cell leukemia","termid":"MONDO:0018935"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0005046"],"is_obsolete":false,"name":"refractory hairy cell leukemia","secondary_identifiers":["MEDGEN:1639342","UMLS:C4551546","DOID:711"],"synonyms":[{"name":"hairy cell leukemia, refractory","type":"exact"},{"name":"refractory hairy cell leukemia","type":"exact"}],"termid":"MONDO:0004110","xrefs":{"Monarch":{"xref_id":"0004110"}}}


id: GO:0046481
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + UDP-D-galactose = 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn-glycerol + H+ + UDP.","definition_xrefs":["EC:2.4.1.241","RHEA:10520"],"direct_ancestors":[{"relation_name":"is_a","term_name":"UDP-galactosyltransferase activity","termid":"GO:0035250"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016757"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016757","GO:0016740"],"is_obsolete":false,"name":"digalactosyldiacylglycerol synthase activity","secondary_identifiers":["Wikipedia:Digalactosyldiacylglycerol_synthase","KEGG_REACTION:R04469","MetaCyc:RXN-1225"],"synonyms":[{"name":"DGD1","type":"narrow"},{"name":"DGD2","type":"narrow"},{"name":"DGDG synthase activity","type":"broad"},{"name":"UDP-galactose-dependent DGDG synthase activity","type":"related"},{"name":"UDP-galactose-dependent digalactosyldiacylglycerol synthase activity","type":"related"},{"name":"UDP-galactose:3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol 6-alpha-galactosyltransferase activity","type":"related"},{"name":"UDP-galactose:MGDG galactosyltransferase activity","type":"exact"}],"termid":"GO:0046481"}


id: PBO:0058135
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4435-1","termid":"PBO:0058135"}


id: PBO:0041450
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 9 putative open reading frame 163","termid":"PBO:0041450"}


id: MONDO:0010311
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Becker muscular dystrophy (BMD) is a neuromuscular disease characterized by progressive muscle wasting and weakness due to degeneration of skeletal, smooth and cardiac muscle.","definition_xrefs":["Orphanet:98895"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DMD-related muscular dystrophy","termid":"MONDO:0700285"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0005336"],"is_obsolete":false,"name":"Becker muscular dystrophy","secondary_identifiers":["UMLS:C0917713","NANDO:2200865","NCIT:C84587","OMIM:300376","SCTID:387732009","DOID:9883","MESH:C570377","GARD:5900","NANDO:1200489","MedDRA:10059117","MEDGEN:182959","icd11.foundation:690532643"],"synonyms":[{"name":"BMD","type":"exact"},{"name":"Becker dystrophinopathy","type":"exact"},{"name":"Becker muscular dystrophy","type":"exact"},{"name":"Becker muscular dystrophy, X-linked recessive","type":"exact"},{"name":"Becker's muscular dystrophy","type":"related"},{"name":"benign congenital myopathy","type":"exact"},{"name":"benign pseudohypertrophic muscular dystrophy","type":"exact"},{"name":"muscular dystrophy pseudohypertrophic progressive, Becker type","type":"related"},{"name":"muscular dystrophy, Becker type","type":"related"},{"name":"muscular dystrophy, pseudohypertrophic progressive, Becker type","type":"related"}],"termid":"MONDO:0010311","xrefs":{"Monarch":{"xref_id":"0010311"}}}


id: GO:0050888
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The determination of where on the body surface, within the body or in the environment a stimulus originates.","definition_xrefs":["ISBN:0721619908"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sensory processing","termid":"GO:0050893"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"determination of stimulus location","termid":"GO:0050888"}


id: PBO:0045317
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"deoxynucleotidyltransferase terminal interacting protein 2","termid":"PBO:0045317"}


id: GO:0160051
data:
  {"annotated_genes":["SJAG_00290","SJAG_04921","SJAG_00861"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[93065,100696,108831],"is_not":false,"summary":null,"term":"GO:0160051"}]},"cv_name":"cellular_component","definition":"A corepressor complex containing the WD-repeat protein Tup1p (S. cerevisiae) and Tup11/Tup12 (fission yeast) and the TPR repeat protein Cyc8p (S. cerevisiae) ssn6 (fission yeast) that is recruited to target genes by DNA-bound repressor proteins preferentially at regions where histones are deacetylated by the Clr6 class I HDAC, and recruits the SWI/SNF and SAGA complexes to promoters.","definition_xrefs":["GOC:vw","PMID:22156212","PMID:10871883","PMID:17101775"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA polymerase II transcription repressor complex","termid":"GO:0090571"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00290":null,"SJAG_00861":null,"SJAG_04921":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005634"}],"interesting_parent_ids":["GO:0032991","GO:0005634","GO:0005575"],"is_obsolete":false,"name":"Cyc8(Ssn6)-Tup1 general repressor complex","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"Tup11/Tup12 repressor complex","type":"exact"}],"termid":"GO:0160051","terms_by_termid":{"GO:0160051":null}}


id: MONDO:0016698
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A WHO grade II, slow growing tumor of children and young adults, usually located intraventricularly. It is the most common ependymal neoplasm. It often causes clinical symptoms by blocking cerebrospinal fluid pathways. Key histological features include perivascular pseudorosettes and ependymal rosettes. (WHO)","definition_xrefs":["NCIT:C3017"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"benign glioma","termid":"MONDO:0000638"},{"relation_name":"excluded_subClassOf","term_name":"low grade ependymoma","termid":"MONDO:0016697"},{"relation_name":"is_a","term_name":"ependymal tumor","termid":"MONDO:0003266"},{"relation_name":"is_a","term_name":"grade II glioma","termid":"MONDO:0021639"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ependymoma","secondary_identifiers":["MESH:D004806","GARD:6353","EFO:1000028","Orphanet:251636","MEDGEN:41825","UMLS:C0014474","DOID:4844","ONCOTREE:EPM","MedDRA:10014967","NANDO:2200088","ICDO:9391/3"],"synonyms":[{"name":"WHO grade II ependymal neoplasm","type":"narrow"},{"name":"WHO grade II ependymal tumor","type":"narrow"},{"name":"WHO grade II ependymal tumour","type":"narrow"},{"name":"benign ependymoma","type":"exact"},{"name":"clear cell ependymoma (histologic variant)","type":"related"},{"name":"ependymoma","type":"exact"},{"name":"ependymoma, benign","type":"narrow"},{"name":"ependymoma, familial","type":"related"},{"name":"epithelial ependymoma","type":"exact"},{"name":"papillary ependymoma (histologic variant)","type":"related"},{"name":"tanycytic ependymoma (histologic variant)","type":"related"}],"termid":"MONDO:0016698","xrefs":{"Monarch":{"xref_id":"0016698"}}}


id: GO:0008045
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues.","definition_xrefs":["CL:0000100","GOC:pr","ISBN:0878932437"],"direct_ancestors":[{"relation_name":"is_a","term_name":"axon guidance","termid":"GO:0007411"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"motor neuron axon guidance","synonyms":[{"name":"motoneuron axon guidance","type":"exact"},{"name":"motor axon guidance","type":"exact"},{"name":"motor axon pathfinding","type":"exact"}],"termid":"GO:0008045"}


id: PBO:0075926
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ST13, Hsp70 interacting protein pseudogene 18","termid":"PBO:0075926"}


id: MONDO:0020676
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete disorder of central nervous system or retinal vasculature (obsolete MONDO:0020676)","synonyms":[{"name":"central nervous system or retinal vascular disease","type":"exact"},{"name":"retina/CNS vascular disease","type":"exact"}],"termid":"MONDO:0020676","xrefs":{"Monarch":{"xref_id":"0020676"}}}


id: GO:0090427
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that starts the inactive process of meiosis.","definition_xrefs":["GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of meiotic nuclear division","termid":"GO:0045836"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0140013"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0007049"},{"rel_name":"positively_regulates","termid":"GO:0140013"},{"rel_name":"regulates","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0140013","GO:0008150","GO:0007049"],"is_obsolete":false,"name":"activation of meiosis","termid":"GO:0090427"}


id: PBO:0040834
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"baculoviral IAP repeat containing 8","termid":"PBO:0040834"}


id: GO:0005595
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A collagen homotrimer of alpha1(XII) chains; type XII collagen triple helices may link sheet-forming or fibrillar collagens to other structures.","definition_xrefs":["ISBN:0721639976"],"direct_ancestors":[{"relation_name":"is_a","term_name":"FACIT collagen trimer","termid":"GO:0005593"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"collagen type XII trimer","termid":"GO:0005595"}


id: PBO:0061106
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NLR family CARD domain containing 4","termid":"PBO:0061106"}


id: MONDO:0006469
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An adamantinoma arising from the tibia. The tibia is the site which is more frequently involved by adamantinoma (80-90% of cases).","definition_xrefs":["NCIT:C8461"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cancer of long bone of lower limb","termid":"MONDO:0000952"},{"relation_name":"is_a","term_name":"adamantinoma","termid":"MONDO:0002422"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"tibial adamantinoma","secondary_identifiers":["MEDGEN:220874","UMLS:C1273017","DOID:6322","SCTID:281702006"],"synonyms":[{"name":"adamantinoma of tibia","type":"exact"},{"name":"tibia adamantinoma","type":"exact"},{"name":"tibia long bone adamantinoma","type":"exact"},{"name":"tibial adamantinoma","type":"exact"},{"name":"tibial adamantinoma morphology","type":"exact"}],"termid":"MONDO:0006469","xrefs":{"Monarch":{"xref_id":"0006469"}}}


id: PBO:0016545
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complements S. cerevisiae SRT1 and RER2","termid":"PBO:0016545"}


id: FYPO:0005886
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more heat shock elements (HSEs) occurs to a greater extent than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased transcription during vegetative growth","termid":"FYPO:0000780"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000294"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001985","FYPO:0000294","FYPO:0001320","FYPO:0006551","FYPO:0005447"],"is_obsolete":false,"name":"increased transcription from HSE promoter","synonyms":[{"name":"expression of Hsf1 target genes increased","type":"related"},{"name":"increased transcription from HSE promoter during mitotic cell cycle","type":"related"},{"name":"increased transcription from HSE promoter during vegetative growth","type":"exact"}],"termid":"FYPO:0005886"}


id: GO:0033595
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to hydroxyisoflavone","termid":"GO:0033594"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to genistein","termid":"GO:0033595"}


id: MONDO:0007471
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Doyne honeycomb retinal dystrophy (DHRD) is a condition that affects the eyes and causes vision loss. It is characterized bysmall, round, white spots known as drusen that accumulate beneath the retinal pigment epithelium(the pigmented layer of the retina). Over time, drusen may grow and come together, creating a honeycomb pattern. It usually begins in early to mid adulthood, but the age of onset varies.The degree of vision loss also varies. DHRD is usually caused by mutations in the EFEMP1 gene and is inherited in an autosomal dominant manner.","direct_ancestors":[{"relation_name":"is_a","term_name":"retinal drusen","termid":"MONDO:0006949"},{"relation_name":"is_a","term_name":"familial flecked retinopathy","termid":"MONDO:0016420"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"Doyne honeycomb retinal dystrophy","secondary_identifiers":["UMLS:C1832174","GARD:1912","Orphanet:75376","DOID:0060745","MEDGEN:321900","ICD10CM:H35.5","OMIM:126600","SCTID:193411004"],"synonyms":[{"name":"DHD","type":"related"},{"name":"DHRD","type":"exact"},{"name":"Doyne honeycomb degeneration of retina","type":"exact"},{"name":"Doyne honeycomb retinal dystrophy","type":"exact"},{"name":"Malattia leventinese","type":"exact"},{"name":"dominant drusen","type":"exact"},{"name":"dominant radial drusen","type":"exact"},{"name":"drusen, radial, autosomal dominant","type":"related"},{"name":"familial drusen","type":"related"}],"termid":"MONDO:0007471","xrefs":{"Monarch":{"xref_id":"0007471"}}}


id: GO:1902458
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of stomatal opening.","definition_xrefs":["GOC:TermGenie","PMID:23766366"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cellular process","termid":"GO:0048522"},{"relation_name":"is_a","term_name":"regulation of stomatal opening","termid":"GO:1902456"},{"relation_name":"positively_regulates","term_name":"stomatal opening","termid":"GO:1990069"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of stomatal opening","synonyms":[{"name":"activation of stomatal opening","type":"narrow"},{"name":"up regulation of stomatal opening","type":"exact"},{"name":"up-regulation of stomatal opening","type":"exact"},{"name":"upregulation of stomatal opening","type":"exact"}],"termid":"GO:1902458"}


id: FYPO:0004922
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell morphology phenotype in which a vegetative cell is inviable, contains one nucleus, has no septum, is elongated, and progression through the mitotic cell cycle is arrested at the mitotic G2/M phase transition.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inviable elongated mononucleate aseptate cell","termid":"FYPO:0000839"},{"relation_name":"is_a","term_name":"inviable mononucleate aseptate cell with cell cycle arrest at mitotic G2/M phase transition","termid":"FYPO:0005367"},{"relation_name":"is_a","term_name":"inviable elongated mononucleate cell with cell cycle arrest at mitotic G2/M phase transition","termid":"FYPO:0007701"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"has_part","termid":"FYPO:0000004"},{"rel_name":"is_a","termid":"FYPO:0000005"},{"rel_name":"has_part","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"has_part","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000004"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"has_part","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0000631"},{"rel_name":"has_part","termid":"FYPO:0000005"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0000032"},{"rel_name":"has_part","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000004","FYPO:0000032","FYPO:0000005","FYPO:0001320","FYPO:0000631","FYPO:0005447","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"inviable elongated mononucleate aseptate cell with cell cycle arrest at mitotic G2/M phase transition","synonyms":[{"name":"elongated inviable mononucleate aseptate cell with mitotic cell cycle arrest at mitotic G2/M phase transition during vegetative growth","type":"exact"},{"name":"elongated inviable mononucleate aseptate vegetative cell with cell cycle arrest at mitotic G2/M phase transition","type":"exact"},{"name":"inviable elongated mononucleate aseptate vegetative cell arrested at G2/M","type":"exact"},{"name":"inviable elongated mononucleate aseptate vegetative cell with cell cycle arrest at mitotic G2/M phase transition","type":"exact"},{"name":"inviable elongated mononucleate aseptate vegetative cell with cell cycle arrest at mitotic G2/M phase transition during mitotic cell cycle","type":"exact"},{"name":"inviable elongated mononucleate aseptate vegetative cell with cell cycle arrest in mitotic G2 phase","type":"related"},{"name":"inviable elongated mononucleate aseptate vegetative cell with mitotic G2/M phase transition arrest","type":"exact"},{"name":"inviable elongated mononucleate aseptate vegetative cell with mitotic cell cycle arrest at mitotic G2/M phase transition","type":"exact"},{"name":"lethal; elongated mononucleate aseptate vegetative cell with cell cycle arrest at mitotic G2/M phase transition","type":"exact"},{"name":"mitotic G2-phase arrested elongated inviable mononucleate aseptate vegetative cell","type":"related"},{"name":"mitotic cell cycle arrest in G2-phase with elongated inviable mononucleate aseptate cell","type":"related"}],"termid":"FYPO:0004922"}


id: PBO:0113012
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Atypical protein kinase; along with paralog, ALK2, required for proper spindle positioning and nuclear segregation following mitotic arrest, proper organization of formins and polarisome components in mitosis, and survival after spindle assembly checkpoint delay; regulates the morphogenesis checkpoint in response to polarity insults through inactivation of Mih1p; phosphorylated in response to DNA damage; similar to mammalian haspins","termid":"PBO:0113012"}


id: GO:0071857
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a beta-endorphin receptor.","definition_xrefs":["GOC:mah","GOC:kmv"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neuropeptide receptor binding","termid":"GO:0071855"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0005515"}],"interesting_parent_ids":["GO:0005488","GO:0005515","GO:0003674"],"is_obsolete":false,"name":"beta-endorphin receptor binding","termid":"GO:0071857"}


id: PBO:0066562
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"rhomboid domain containing 1","termid":"PBO:0066562"}


id: GO:0043381
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the rate of memory T cell differentiation.","definition_xrefs":["ISBN:0781735149"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of immune effector process","termid":"GO:0002698"},{"relation_name":"is_a","term_name":"regulation of memory T cell differentiation","termid":"GO:0043380"},{"relation_name":"is_a","term_name":"negative regulation of T cell differentiation","termid":"GO:0045581"},{"relation_name":"is_a","term_name":"negative regulation of immune response","termid":"GO:0050777"},{"relation_name":"negatively_regulates","term_name":"memory T cell differentiation","termid":"GO:0043379"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0007155"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0007155"}],"interesting_parent_ids":["GO:0007155","GO:0008150"],"is_obsolete":false,"name":"negative regulation of memory T cell differentiation","synonyms":[{"name":"down regulation of memory T cell differentiation","type":"exact"},{"name":"down-regulation of memory T cell differentiation","type":"exact"},{"name":"downregulation of memory T cell differentiation","type":"exact"},{"name":"inhibition of memory T cell differentiation","type":"narrow"},{"name":"negative regulation of memory T cell development","type":"related"},{"name":"negative regulation of memory T lymphocyte differentiation","type":"exact"},{"name":"negative regulation of memory T-cell differentiation","type":"exact"},{"name":"negative regulation of memory T-lymphocyte differentiation","type":"exact"}],"termid":"GO:0043381"}


id: PBO:0079897
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquinol-cytochrome c reductase complex assembly factor 6","termid":"PBO:0079897"}


id: PBO:0077388
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein 128","termid":"PBO:0077388"}


id: GO:0048442
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the sepal over time, from its formation to the mature structure.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"floral organ development","termid":"GO:0048437"},{"relation_name":"is_a","term_name":"phyllome development","termid":"GO:0048827"},{"relation_name":"part_of","term_name":"flower calyx development","termid":"GO:0048464"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"sepal development","secondary_identifiers":["GO:0048421"],"termid":"GO:0048442"}


id: PBO:0054891
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2305","termid":"PBO:0054891"}


id: PBO:0053423
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 365","termid":"PBO:0053423"}


id: GO:0052365
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of xylan within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.","definition_xrefs":["ISBN:0198547684"],"gene_count":0,"genotype_count":0,"name":"obsolete catabolism by host of symbiont xylan (obsolete GO:0052365)","termid":"GO:0052365"}


id: MONDO:0011878
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete Worth syndrome (obsolete MONDO:0011878)","termid":"MONDO:0011878","xrefs":{"Monarch":{"xref_id":"0011878"}}}


id: GO:0020028
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of hemoglobin into a cell by receptor-mediated endocytosis.","definition_xrefs":["GOC:mb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"receptor-mediated endocytosis","termid":"GO:0006898"},{"relation_name":"is_a","term_name":"protein transport","termid":"GO:0015031"},{"relation_name":"is_a","term_name":"protein localization to organelle","termid":"GO:0033365"},{"relation_name":"is_a","term_name":"establishment of protein localization to organelle","termid":"GO:0072594"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0016192"}],"interesting_parent_ids":["GO:0016192","GO:0006810","GO:0051179","GO:0008150"],"is_obsolete":false,"name":"endocytic hemoglobin import into cell","synonyms":[{"name":"endocytic hemoglobin import","type":"related"},{"name":"haemoglobin uptake","type":"exact"},{"name":"hemoglobin uptake","type":"exact"}],"termid":"GO:0020028"}


id: GO:0102657
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 1-18:1-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:1-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.","definition_xrefs":["GOC:pz","PMID:15579662"],"gene_count":0,"genotype_count":0,"name":"obsolete 1-18:1-2-16:0-monogalactosyldiacylglycerol palmitoyl-lipid 7-desaturase activity (obsolete GO:0102657)","termid":"GO:0102657"}


id: PBO:0090556
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"assembly chaperone for ribosomal protein Rpl4, TPR repeat protein Acl4","termid":"PBO:0090556"}


id: PBO:0090163
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"karyopherin/importin-beta family nuclear import receptor Mtr10","termid":"PBO:0090163"}


id: PBO:0073642
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sialic acid binding Ig like lectin 29, pseudogene","termid":"PBO:0073642"}


id: GO:0098816
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"excitatory postsynaptic potential","termid":"GO:0060079"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"mini excitatory postsynaptic potential","termid":"GO:0098816"}


id: PBO:0083755
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Essential DNA-binding transcription regulator that binds many loci; involved in transcription activation, repression, chromatin silencing, telomere length maintenance; represses divergent noncoding transcription at highly expressed genes, prevents transcription initiation at cryptic promoters near its binding sites; relocalizes to cytosol under hypoxia; recruits Sir complex to telomeric DNA; present in quiescent cell telomere hyperclusters","termid":"PBO:0083755"}


id: PBO:0076016
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/threonine kinase 10","termid":"PBO:0076016"}


id: PBO:0077114
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"translocase of inner mitochondrial membrane 23","termid":"PBO:0077114"}


id: PBO:0036519
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphoprotein phosphatase involved in unfolded protein response Dcr2 (predicted)","termid":"PBO:0036519"}


id: PBO:0050489
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HOXB cluster antisense RNA 4","termid":"PBO:0050489"}


id: GO:0051265
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: diolein + mono-olein = triolein + glycerol. Mono-olein, also known as mono-oleoylglycerol, is the monoglyceride formed from oleic acid, 9-octodecenoic acid; diolein is also known as dioleoylglycerol, and triolein as trioleoylglycerol and olein.","definition_xrefs":["PMID:15364929","GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acylglycerol O-acyltransferase activity","termid":"GO:0016411"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016746"}],"interesting_parent_ids":["GO:0016746","GO:0003674","GO:0016740","GO:0003824"],"is_obsolete":false,"name":"diolein transacylation activity","synonyms":[{"name":"DOG transacylation","type":"exact"},{"name":"acyl-CoA-independent diolein transacylation","type":"exact"},{"name":"dioleoylglycerol O-acyltransferase activity","type":"exact"},{"name":"dioleoylglycerol transacylase activity","type":"exact"}],"termid":"GO:0051265"}


id: PBO:0051058
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin heavy diversity 3-10","termid":"PBO:0051058"}


id: GO:1902722
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of prolactin secretion.","definition_xrefs":["PMID:16159377","GOC:TermGenie","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of protein secretion","termid":"GO:0050714"},{"relation_name":"is_a","term_name":"positive regulation of peptide hormone secretion","termid":"GO:0090277"},{"relation_name":"positively_regulates","term_name":"prolactin secretion","termid":"GO:0070459"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"positively_regulates","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0006810","GO:0023052","GO:0008150"],"is_obsolete":false,"name":"positive regulation of prolactin secretion","synonyms":[{"name":"activation of prolactin secretion","type":"narrow"},{"name":"up regulation of prolactin secretion","type":"exact"},{"name":"up-regulation of prolactin secretion","type":"exact"},{"name":"upregulation of prolactin secretion","type":"exact"}],"termid":"GO:1902722"}


id: GO:0006816
data:
  {"annotated_genes":["SJAG_03631","SJAG_04096","SJAG_05229","SJAG_02877","SJAG_04668","SJAG_02532","SJAG_04757","SJAG_04698","SJAG_04551","SJAG_01400","SJAG_04471","SJAG_00296","SJAG_02322","SJAG_03850","SJAG_02019","SJAG_04028","SJAG_03399","SJAG_01090","SJAG_02440"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[99161],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0036444"},{"annotations":[68221,76193,116296,94212],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0098703"},{"annotations":[117425],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140146"},{"annotations":[67178,74160,96636,71259,111216,75255,80159,97270],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070588"},{"annotations":[93012],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061856"},{"annotations":[115218,93030],"is_not":false,"rel_names":["negatively_regulates","regulates"],"summary":null,"term":"GO:1905949"},{"annotations":[103962],"is_not":false,"rel_names":["regulates","positively_regulates"],"summary":null,"term":"GO:1905665"},{"annotations":[110506],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061454"}]},"cv_name":"biological_process","definition":"The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"metal ion transport","termid":"GO:0030001"}],"gene_count":19,"genes_by_uniquename":{"SJAG_00296":null,"SJAG_01090":null,"SJAG_01400":null,"SJAG_02019":null,"SJAG_02322":null,"SJAG_02440":null,"SJAG_02532":null,"SJAG_02877":null,"SJAG_03399":null,"SJAG_03631":null,"SJAG_03850":null,"SJAG_04028":null,"SJAG_04096":null,"SJAG_04471":null,"SJAG_04551":null,"SJAG_04668":null,"SJAG_04698":null,"SJAG_04757":null,"SJAG_05229":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0051179","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"calcium ion transport","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null,"GO_REF:0000108":null},"synonyms":[{"name":"calcium transport","type":"exact"},{"name":"mitochondrial sodium/calcium ion exchange","type":"narrow"},{"name":"sodium:calcium exchange","type":"narrow"}],"termid":"GO:0006816","terms_by_termid":{"GO:0036444":null,"GO:0061454":null,"GO:0061856":null,"GO:0070588":null,"GO:0098703":null,"GO:0140146":null,"GO:1905665":null,"GO:1905949":null}}


id: PBO:0027004
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-fragmented_DNA_during_meiotic_cell_cycle","termid":"PBO:0027004"}


id: PATO:0001922
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A positional quality inhering in a bearer by virtue of the bearer's being positioned towards the rear of an organism.","definition_xrefs":["PATOC:mb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mislocalised","termid":"PATO:0000628"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mislocalised posteriorly","termid":"PATO:0001922"}


id: GO:0009195
data:
  {"annotated_genes":["SJAG_03676"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[78196],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006256"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar.","definition_xrefs":["GOC:go_curators","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pyrimidine nucleoside diphosphate catabolic process","termid":"GO:0009140"},{"relation_name":"is_a","term_name":"ribonucleoside diphosphate catabolic process","termid":"GO:0009191"},{"relation_name":"is_a","term_name":"pyrimidine ribonucleoside diphosphate metabolic process","termid":"GO:0009193"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03676":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0055086"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0055086"],"is_obsolete":false,"name":"pyrimidine ribonucleoside diphosphate catabolic process","references_by_uniquename":{"GO_REF:0000033":null},"synonyms":[{"name":"pyrimidine ribonucleoside diphosphate breakdown","type":"exact"},{"name":"pyrimidine ribonucleoside diphosphate catabolism","type":"exact"},{"name":"pyrimidine ribonucleoside diphosphate degradation","type":"exact"}],"termid":"GO:0009195","terms_by_termid":{"GO:0006256":null}}


id: MONDO:0001419
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare squamous cell carcinoma that arises from the mucosal lining of the trachea. It usually grows as an intraluminal mass and later invades extraluminal structures. The majority of patients present with hemoptysis, coughing, dyspnea, or stridor.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"trachea carcinoma","termid":"MONDO:0003184"},{"relation_name":"is_a","term_name":"squamous cell carcinoma","termid":"MONDO:0005096"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"trachea squamous cell carcinoma","secondary_identifiers":["MEDGEN:91059","UMLS:C0345946","EFO:1000600","NCIT:C4448","SCTID:254620000","DOID:12003"],"synonyms":[{"name":"epidermoid carcinoma of the trachea","type":"exact"},{"name":"epidermoid carcinoma of trachea","type":"exact"},{"name":"squamous cell carcinoma of the trachea","type":"exact"},{"name":"squamous cell carcinoma of trachea","type":"exact"},{"name":"trachea epidermoid carcinoma","type":"exact"},{"name":"trachea squamous cell carcinoma","type":"exact"},{"name":"tracheal epidermoid carcinoma","type":"exact"},{"name":"tracheal squamous cell carcinoma","type":"exact"}],"termid":"MONDO:0001419","xrefs":{"Monarch":{"xref_id":"0001419"}}}


id: PBO:0078825
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Pro (anticodon AGG) 2-8","termid":"PBO:0078825"}


id: FYPO:0006092
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patches are localized more towards the end of the cell, with fewer patches in the lateral cortex, than normal.","definition_xrefs":["PomBase:mah","PMID:20705471"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mislocalized actin cortical patches during vegetative growth","termid":"FYPO:0003988"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0004803"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0000138"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0005447","FYPO:0001985","FYPO:0004803","FYPO:0000002","FYPO:0000138"],"is_obsolete":false,"name":"polarized actin cortical patch localization during vegetative growth","synonyms":[{"name":"polarised actin cortical patch localisation during vegetative growth","type":"exact"},{"name":"polarized F-actin patch localization during vegetative growth","type":"exact"},{"name":"polarized actin cortical patch localization during mitotic cell cycle","type":"related"},{"name":"polarized actin cortical patch location during vegetative growth","type":"related"},{"name":"polarized actin patch localization during vegetative growth","type":"exact"}],"termid":"FYPO:0006092"}


id: PBO:0114137
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sulphite transmembrane transporter Ssu4","termid":"PBO:0114137"}


id: PBO:0030424
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-elongated,_constricted_nucleus","termid":"PBO:0030424"}


id: PBO:0051757
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"inositol polyphosphate multikinase pseudogene 1","termid":"PBO:0051757"}


id: MONDO:0016769
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Linear lichen planus (LLP), also referred to as Blaschkoid LP, is a rare type of lichen planus characterized by a linear distribution of lichenoid lesions along the lines of Blaschko, which are embryonic pathways of skin development.","definition_xrefs":["Orphanet:254379"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lichen planus","termid":"MONDO:0006572"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"linear lichen planus","secondary_identifiers":["GARD:11898","UMLS:C0023650","MEDGEN:507921","SCTID:44509000","icd11.foundation:7180779"],"synonyms":[{"name":"Blaschkoid LP","type":"exact"},{"name":"Blaschkoid lichen planus","type":"exact"},{"name":"linear LP","type":"exact"},{"name":"llp","type":"related"}],"termid":"MONDO:0016769","xrefs":{"Monarch":{"xref_id":"0016769"}}}


id: GO:0000187
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The initiation of the activity of the inactive enzyme MAP kinase (MAPK).","definition_xrefs":["PMID:9561267"],"gene_count":0,"genotype_count":0,"name":"obsolete activation of MAPK activity (obsolete GO:0000187)","synonyms":[{"name":"MAPK activation","type":"exact"},{"name":"activation of MAP kinase","type":"exact"},{"name":"activation of MAPK activity during sporulation","type":"narrow"}],"termid":"GO:0000187"}


id: SO:0000716
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"An mRNA that has the quality dicistronic.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"has_quality","term_name":"dicistronic","termid":"SO:0000879"},{"relation_name":"is_a","term_name":"dicistronic_transcript","termid":"SO:0000079"},{"relation_name":"is_a","term_name":"polycistronic_mRNA","termid":"SO:0000634"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dicistronic_mRNA","synonyms":[{"name":"dicistronic mRNA","type":"exact"},{"name":"dicistronic processed transcript","type":"related"}],"termid":"SO:0000716"}


id: PBO:0079028
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Val (anticodon AAC) 1-1","termid":"PBO:0079028"}


id: MONDO:0014648
data:
  {"annotated_genes":["SJAG_01625"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86902],"is_not":false,"summary":null,"term":"MONDO:0014648"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive non-syndromic intellectual disability","termid":"MONDO:0019502"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01625":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0037792"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0005066","MONDO:0037792"],"is_obsolete":false,"name":"Al-Raqad syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:897610","OMIM:616459","UMLS:C4085595"],"synonyms":[{"name":"AL-RAQAD syndrome","type":"related"},{"name":"ARS","type":"related"},{"name":"Al-Raqad syndrome","type":"exact"}],"termid":"MONDO:0014648","terms_by_termid":{"MONDO:0014648":null},"xrefs":{"Monarch":{"xref_id":"0014648"}}}


id: GO:1901039
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of peptide antigen transport.","definition_xrefs":["GOC:TermGenie","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of antigen processing and presentation of peptide antigen","termid":"GO:0002583"},{"relation_name":"is_a","term_name":"regulation of peptide transport","termid":"GO:0090087"},{"relation_name":"regulates","term_name":"peptide antigen transport","termid":"GO:0046968"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810"],"is_obsolete":false,"name":"regulation of peptide antigen transport","termid":"GO:1901039"}


id: FYPO:0004741
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount of filamentous actin (F-actin) in the actomyosin contractile ring is normal (i.e. indistinguishable from wild type) during mitotic anaphase B.","definition_xrefs":["PMID:25688133","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal actomyosin contractile ring","termid":"FYPO:0004740"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"normal F-actin level in actomyosin contractile ring during anaphase B","synonyms":[{"name":"normal F-actin level in actomyosin contractile ring during anaphase B during mitotic cell cycle","type":"related"},{"name":"normal F-actin level in actomyosin contractile ring during anaphase B during vegetative growth","type":"exact"},{"name":"normal F-actin level in contractile ring during anaphase B","type":"exact"},{"name":"normal F-actin level in cytokinetic contractile ring during anaphase B","type":"exact"},{"name":"normal abundance of actin in actomyosin contractile ring in anaphase B","type":"exact"},{"name":"normal actomyosin contractile ring F-actin level during anaphase B","type":"exact"},{"name":"normal filamentous actin level in actomyosin contractile ring during anaphase B","type":"exact"}],"termid":"FYPO:0004741"}


id: MONDO:0035450
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"brain disorder","termid":"MONDO:0005560"},{"relation_name":"is_a","term_name":"disorder of development or morphogenesis","termid":"MONDO:0021147"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aprosencephaly","secondary_identifiers":["Orphanet:566857","GARD:22281","icd11.foundation:1740361952","MEDGEN:140908","UMLS:C0431349","NCIT:C98824"],"termid":"MONDO:0035450","xrefs":{"Monarch":{"xref_id":"0035450"}}}


id: PBO:0046813
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coagulation factor XIII A chain","termid":"PBO:0046813"}


id: MOD:01336
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"OBSOLETE - identical and redundant with MOD:00657. Remap to MOD:00657.","definition_xrefs":["PubMed:18688235"],"gene_count":0,"genotype_count":0,"name":"OBSOLETE MOD:01336 deamidation followed by a methylation -site Q (obsolete MOD:01336)","synonyms":[{"name":"Deamidation followed by a methylation","type":"related"},{"name":"Methyl+Deamidated","type":"related"}],"termid":"MOD:01336"}


id: FYPO_EXT:0000003
data:
  {"annotation_feature_type":"gene","cv_name":"fypo_extensions","definition":"small fraction of cells (penetrance) or weak phenotype (severity)","definition_xrefs":["PomBase:curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"FYPO severity extension","termid":"FYPO_EXT:1000001"},{"relation_name":"is_a","term_name":"FYPO penetrance extension","termid":"FYPO_EXT:1000002"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"low","termid":"FYPO_EXT:0000003"}


id: SO:0001400
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A post translationally modified lysine amino acid feature.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified_amino_acid_feature","termid":"SO:0001385"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"modified_L_lysine","secondary_identifiers":["MOD:00912"],"synonyms":[{"name":"ModLys","type":"exact"},{"name":"modified L lysine","type":"exact"},{"name":"modified L-lysine","type":"exact"}],"termid":"SO:0001400"}


id: GO:0052900
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: H2O + O2 + spermine = 1,3-diaminopropane + H2O2 + N-(3-aminopropyl)-4-aminobutanal. Weak activity on N(1)-acetylspermine and spermine.","definition_xrefs":["RHEA:25824","EC:1.5.3.14"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polyamine oxidase activity","termid":"GO:0046592"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"spermine oxidase (propane-1,3-diamine-forming) activity","secondary_identifiers":["MetaCyc:RXN-6421"],"synonyms":[{"name":"polyamine oxidase (propane-1,3-diamine-forming) activity","type":"broad"}],"termid":"GO:0052900"}


id: MONDO:0004632
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. An obsolete term referring to Hodgkin lymphoma.","definition_xrefs":["NCIT:C6914"],"gene_count":0,"genotype_count":0,"name":"obsolete Hodgkin's granuloma (obsolete MONDO:0004632)","secondary_identifiers":["ICD9:201","NCIT:C26956","SCTID:118602004","ICD9:201.0","ICDO:9661/3","ICD9:201.7","NCIT:C3517","ICD9:201.1","SCTID:118609008","ICD9:201.2","ICD9:201.9","SCTID:118610003","ICD9:201.6","NCIT:C6913","DOID:8651","SCTID:118607005","ICD9:201.4"],"synonyms":[{"name":"Hodgkin granuloma","type":"exact"},{"name":"Hodgkin's granuloma","type":"exact"},{"name":"Hodgkin's granuloma of unspecified site","type":"exact"},{"name":"Hodgkin's granuloma, unspecified site, extranodal and solid organ sites","type":"exact"}],"termid":"MONDO:0004632","xrefs":{"Monarch":{"xref_id":"0004632"}}}


id: PBO:0089458
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphorelay sensor kinase Mak2","termid":"PBO:0089458"}


id: PBO:0079770
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UFM1 pseudogene 3","termid":"PBO:0079770"}


id: GO:0003137
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction.","definition_xrefs":["GOC:mtg_heart"],"gene_count":0,"genotype_count":0,"name":"obsolete Notch signaling pathway involved in heart induction (obsolete GO:0003137)","synonyms":[{"name":"Notch signalling pathway involved in heart induction","type":"exact"}],"termid":"GO:0003137"}


id: MOD:01600
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"The protein modification reporter fragment produced by an Applied Biosystems iTRAQ8plex-119 reagent derivatized residue.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"derives_from","term_name":"iTRAQ8plex-119 reporter+balance reagent acylated residue","termid":"MOD:01570"},{"relation_name":"is_a","term_name":"iTRAQ8plex reporter fragment","termid":"MOD:01593"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"iTRAQ8plex-119 reporter fragment","synonyms":[{"name":"4-methyl-1-methylidenepiperazin-1-ium","type":"exact"}],"termid":"MOD:01600"}


id: PBO:0080662
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WAP four-disulfide core domain 8","termid":"PBO:0080662"}


id: GO:0010811
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.","definition_xrefs":["GOC:pf","GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cell-substrate adhesion","termid":"GO:0010810"},{"relation_name":"is_a","term_name":"positive regulation of cell adhesion","termid":"GO:0045785"},{"relation_name":"positively_regulates","term_name":"cell-substrate adhesion","termid":"GO:0031589"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0007155"},{"rel_name":"regulates","termid":"GO:0007155"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0007155","GO:0008150"],"is_obsolete":false,"name":"positive regulation of cell-substrate adhesion","termid":"GO:0010811"}


id: PBO:0054501
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1901","termid":"PBO:0054501"}


id: MONDO:0012371
data:
  {"annotated_genes":["SJAG_03453"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88441],"is_not":false,"summary":null,"term":"MONDO:0012371"}]},"cv_name":"mondo","definition":"Any Noonan syndrome in which the cause of the disease is a mutation in the KRAS gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Noonan syndrome","termid":"MONDO:0018997"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03453":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005267"],"is_obsolete":false,"name":"Noonan syndrome 3","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C1860991","GARD:9885","DOID:0060581","MESH:C537847","NCIT:C176931","OMIM:609942","MEDGEN:349931"],"synonyms":[{"name":"KRAS Noonan syndrome","type":"exact"},{"name":"KRAS gene related Noonan syndrome","type":"exact"},{"name":"NS3","type":"exact"},{"name":"Noonan syndrome 3","type":"exact"},{"name":"Noonan syndrome caused by mutation in KRAS","type":"exact"},{"name":"Noonan syndrome type 3","type":"exact"}],"termid":"MONDO:0012371","terms_by_termid":{"MONDO:0012371":null},"xrefs":{"Monarch":{"xref_id":"0012371"}}}


id: PR:O74304
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- win1 gene.","definition_xrefs":["UniProtKB:O74304","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MAP kinase kinase kinase win1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1006.09","synonyms":[{"name":"Spom972h-win1","type":"exact"}],"termid":"PR:O74304"}


id: PBO:0002996
data:
  {"annotation_feature_type":"gene","cv_name":"ex_tools","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"gene reporter system","termid":"PBO:0002996"}


id: GO:1900222
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of amyloid-beta clearance.","definition_xrefs":["GOC:TermGenie","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of multicellular organismal process","termid":"GO:0051241"},{"relation_name":"is_a","term_name":"regulation of amyloid-beta clearance","termid":"GO:1900221"},{"relation_name":"negatively_regulates","term_name":"amyloid-beta clearance","termid":"GO:0097242"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of amyloid-beta clearance","synonyms":[{"name":"down regulation of beta-amyloid clearance","type":"exact"},{"name":"down-regulation of beta-amyloid clearance","type":"exact"},{"name":"downregulation of beta-amyloid clearance","type":"exact"},{"name":"inhibition of beta-amyloid clearance","type":"narrow"},{"name":"negative regulation of beta-amyloid clearance","type":"exact"}],"termid":"GO:1900222"}


id: PBO:0074601
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, H/ACA box 11B","termid":"PBO:0074601"}


id: GO:1901587
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of acid-sensing ion channel activity.","definition_xrefs":["GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of acid-sensing ion channel activity (obsolete GO:1901587)","synonyms":[{"name":"activation of ASIC activity","type":"exact"},{"name":"activation of acid-sensing ion channel activity","type":"narrow"},{"name":"positive regulation of ASIC activity","type":"exact"},{"name":"up regulation of ASIC activity","type":"exact"},{"name":"up regulation of acid-sensing ion channel activity","type":"exact"},{"name":"up-regulation of ASIC activity","type":"exact"},{"name":"up-regulation of acid-sensing ion channel activity","type":"exact"},{"name":"upregulation of ASIC activity","type":"exact"},{"name":"upregulation of acid-sensing ion channel activity","type":"exact"}],"termid":"GO:1901587"}


id: PBO:0077427
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein 164","termid":"PBO:0077427"}


id: MONDO:0015294
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Nephrogenic systemic fibrosis (NSF) is a rare systemic fibrosing condition observed in renally impaired patients and characterized by a hardening and thickening of the skin with fibrotic plaques or papules, pruritus, joint pain and stiffness, muscle weakness, limitation of range of motion, and yellowed eyes. It is generally associated with administration of gadolinium-based magnetic resonance imaging contrast agents (GBCA) in patients with kidney disease.","definition_xrefs":["Orphanet:137617"],"direct_ancestors":[{"relation_name":"is_a","term_name":"skin disorder","termid":"MONDO:0005093"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"nephrogenic systemic fibrosis","secondary_identifiers":["MedDRA:10067467","MEDGEN:854737","UMLS:C3888044","MESH:D054989","ICD9:588.89","SCTID:424114000","GARD:9725","NCIT:C84920","icd11.foundation:1537082562","NORD:1498"],"synonyms":[{"name":"NFD","type":"related"},{"name":"NSF","type":"related"},{"name":"nephrogenic fibrosing dermopathy","type":"exact"}],"termid":"MONDO:0015294","xrefs":{"Monarch":{"xref_id":"0015294"}}}


id: GO:0034708
data:
  {"annotated_genes":["SJAG_04181","SJAG_04848","SJAG_04574","SJAG_00341","SJAG_00896","SJAG_04890","SJAG_03949","SJAG_00769","SJAG_02768","SJAG_01540","SJAG_02637","SJAG_04680","SJAG_02119","SJAG_00756","SJAG_02329","SJAG_03680","SJAG_03431","SJAG_01325","SJAG_07011","SJAG_02170","SJAG_02386"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[120687,98534,119553,96154,112327,115837],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0043494"},{"annotations":[80724,98033],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0035657"},{"annotations":[111191,77237,73631,80252,92520,73025,75688,117566],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0048188"},{"annotations":[76679,75889],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031515"},{"annotations":[105955,77141],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0043528"},{"annotations":[117575,59465],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0106143"}]},"cv_name":"cellular_component","definition":"A protein complex that possesses methyltransferase activity.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transferase complex","termid":"GO:1990234"},{"relation_name":"part_of","term_name":"intracellular anatomical structure","termid":"GO:0005622"}],"gene_count":21,"genes_by_uniquename":{"SJAG_00341":null,"SJAG_00756":null,"SJAG_00769":null,"SJAG_00896":null,"SJAG_01325":null,"SJAG_01540":null,"SJAG_02119":null,"SJAG_02170":null,"SJAG_02329":null,"SJAG_02386":null,"SJAG_02637":null,"SJAG_02768":null,"SJAG_03431":null,"SJAG_03680":null,"SJAG_03949":null,"SJAG_04181":null,"SJAG_04574":null,"SJAG_04680":null,"SJAG_04848":null,"SJAG_04890":null,"SJAG_07011":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"methyltransferase complex","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null,"GO_REF:0000117":null},"termid":"GO:0034708","terms_by_termid":{"GO:0031515":null,"GO:0035657":null,"GO:0043494":null,"GO:0043528":null,"GO:0048188":null,"GO:0106143":null}}


id: PBO:0048867
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"golgin A3","termid":"PBO:0048867"}


id: MONDO:0017903
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A genetic variant of mendelian susceptibility to mycobacterial diseases characterized by a partial deficiency in IFN-gammaR2, leading to impaired response to IFN-gamma and, consequently, to recurrent, moderately severe infections with bacillus Calmette-Guerin (BCG) and other environmental mycobacteria (EM).","definition_xrefs":["Orphanet:319589"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inherited susceptibility to mycobacterial diseases","termid":"MONDO:0019146"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"autosomal dominant mendelian susceptibility to mycobacterial diseases due to partial IFNgammaR2 deficiency","secondary_identifiers":["UMLS:C4510875","MEDGEN:1371829"],"synonyms":[{"name":"IFNGR2 autosomal dominant mendelian susceptibility to mycobacterial diseases due to a partial deficiency","type":"exact"},{"name":"autosomal dominant MSMD due to partial IFNgammaR2 deficiency","type":"exact"},{"name":"autosomal dominant MSMD due to partial interferon gamma receptor 2 deficiency","type":"exact"},{"name":"autosomal dominant mendelian susceptibility to mycobacterial diseases due to a partial deficiency caused by mutation in IFNGR2","type":"exact"},{"name":"autosomal dominant mendelian susceptibility to mycobacterial diseases due to partial interferon gamma receptor 2 deficiency","type":"exact"}],"termid":"MONDO:0017903","xrefs":{"Monarch":{"xref_id":"0017903"}}}


id: FYPO:0006084
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which cells show increased sensitivity to cold shock. Cold shock is a form of temperature stress in which cells are briefly exposed to a very low temperature.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased cell population growth at low temperature","termid":"FYPO:0000080"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0002057"}],"interesting_parent_ids":["FYPO:0000139","FYPO:0005447","FYPO:0002060","FYPO:0002058","FYPO:0002057","FYPO:0001985","FYPO:0000003"],"is_obsolete":false,"name":"sensitive to cold shock","synonyms":[{"name":"decreased growth during cellular response to cold shock","type":"exact"},{"name":"decreased vegetative cell population growth during cellular response to cold shock","type":"exact"},{"name":"hypersensitive to cold shock","type":"exact"}],"termid":"FYPO:0006084"}


id: FYPO:0007329
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of DNA damage measured at transfer RNA genes in a cell is greater than normal. The number, extent, or both of damage sites may be increased.","definition_xrefs":["PomBase:mah","PMID:31833215"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased DNA damage during vegetative growth","termid":"FYPO:0003547"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002"],"is_obsolete":false,"name":"increased DNA damage at tRNA genes","synonyms":[{"name":"increased DNA damage at tRNA genes during mitotic cell cycle","type":"related"},{"name":"increased DNA damage at tRNA genes during vegetative growth","type":"exact"},{"name":"increased DNA damage at transfer RNA genes","type":"exact"},{"name":"increased number of DNA lesions at tRNA genes during vegetative growth","type":"related"}],"termid":"FYPO:0007329"}


id: GO:0070532
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that contains the BRCA1-BARD1 heterodimer, BACH1 and TopBP1, and binds to DNA during S phase at DNA damage sites.","definition_xrefs":["PMID:16391231","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nuclear protein-containing complex","termid":"GO:0140513"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005634"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0032991","GO:0005575","GO:0005634"],"is_obsolete":false,"name":"BRCA1-B complex","termid":"GO:0070532"}


id: GO:0072704
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercaptoethanol stimulus.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to alcohol","termid":"GO:0097305"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to mercaptoethanol","synonyms":[{"name":"response to 2-sulfanylethanol","type":"exact"}],"termid":"GO:0072704"}


id: PBO:0072945
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small Cajal body-specific RNA 26A","termid":"PBO:0072945"}


id: GO:0061902
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidylinositol-3-kinase activity.","definition_xrefs":["GOC:aruk","PMID:18723082","GOC:bc"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of 1-phosphatidylinositol-3-kinase activity (obsolete GO:0061902)","termid":"GO:0061902"}


id: MONDO:0056803
data:
  {"annotated_genes":["SJAG_02007","SJAG_00582","SJAG_03553","SJAG_03701","SJAG_03641","SJAG_01612","SJAG_00988","SJAG_01162","SJAG_04459","SJAG_03671","SJAG_02397","SJAG_01417","SJAG_03290","SJAG_03222","SJAG_01995","SJAG_04042","SJAG_01070","SJAG_03712","SJAG_01164","SJAG_04016","SJAG_01199","SJAG_03316","SJAG_01351","SJAG_03556","SJAG_02306","SJAG_03069","SJAG_01466","SJAG_03659","SJAG_04425","SJAG_02895","SJAG_01147","SJAG_01063","SJAG_01216"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87444],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009825"},{"annotations":[87416],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0100255"},{"annotations":[87110],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009352"},{"annotations":[86806],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009058"},{"annotations":[88824],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0015003"},{"annotations":[88016,88015],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009285"},{"annotations":[87691],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009259"},{"annotations":[87564],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009947"},{"annotations":[88000],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009284"},{"annotations":[88662],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0019531"},{"annotations":[88067],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009666"},{"annotations":[87054,87055],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009353"},{"annotations":[88715],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013404"},{"annotations":[88439],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013762"},{"annotations":[87226],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014576"},{"annotations":[87755],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009607"},{"annotations":[87031,87032],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009354"},{"annotations":[87642],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009609"},{"annotations":[88473],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010184"},{"annotations":[86927],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011582"},{"annotations":[88648],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0975806"},{"annotations":[87454],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013675"},{"annotations":[87810],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014132"},{"annotations":[87075],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014611"},{"annotations":[87141],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0033282"},{"annotations":[87783],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0054785"},{"annotations":[88134],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0957382"},{"annotations":[88803],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0971174"},{"annotations":[86994],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009529"},{"annotations":[87583],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014803"},{"annotations":[86934],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009593"}]},"cv_name":"mondo","definition":"A disease that has its basis in the disruption of sulfur compound metabolic process.","definition_xrefs":["MONDO:patterns/disrupts_process"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mineral metabolism 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disease","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["SCTID:123809005","MEDGEN:688004","UMLS:C1263724"],"synonyms":[{"name":"disorder of sulfur compound metabolic process","type":"exact"},{"name":"disorder of sulfur metabolic process","type":"exact"},{"name":"disorder of sulfur metabolism","type":"exact"},{"name":"disorder of sulphur compound metabolic process","type":"exact"},{"name":"disorder of sulphur metabolic process","type":"exact"},{"name":"disorder of sulphur metabolism","type":"exact"},{"name":"sulfur compound metabolic process disease","type":"exact"},{"name":"sulphur compound metabolic process disease","type":"exact"}],"termid":"MONDO:0056803","terms_by_termid":{"MONDO:0009058":null,"MONDO:0009259":null,"MONDO:0009284":null,"MONDO:0009285":null,"MONDO:0009352":null,"MONDO:0009353":null,"MONDO:0009354":null,"MONDO:0009529":null,"MONDO:0009593":null,"MONDO:0009607":null,"MONDO:0009609":null,"MONDO:0009666":null,"MONDO:0009825":null,"MONDO:0009947":null,"MONDO:0010184":null,"MONDO:0011582":null,"MONDO:0013404":null,"MONDO:0013675":null,"MONDO:0013762":null,"MONDO:0014132":null,"MONDO:0014576":null,"MONDO:0014611":null,"MONDO:0014803":null,"MONDO:0015003":null,"MONDO:0019531":null,"MONDO:0033282":null,"MONDO:0054785":null,"MONDO:0100255":null,"MONDO:0957382":null,"MONDO:0971174":null,"MONDO:0975806":null},"xrefs":{"Monarch":{"xref_id":"0056803"}}}


id: PBO:0087470
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex; required for repression of a-specific genes, repression of early meiotic genes during mitotic growth, and repression of INO1; similar to mammalian Acf1p, the regulatory subunit of the mammalian ATP-utilizing chromatin assembly and modifying factor (ACF) complex; ITC1 has a paralog, YPL216W, that arose from the whole genome duplication","termid":"PBO:0087470"}


id: PBO:0072149
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S15a pseudogene 26","termid":"PBO:0072149"}


id: PBO:0028865
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_mRNA_level_during_vegetative_growth","termid":"PBO:0028865"}


id: PBO:0070872
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L15 pseudogene 3","termid":"PBO:0070872"}


id: FYPO:0003307
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell population phenotype in which the mitotic index is higher than normal. The mitotic index is the proportion of the population undergoing mitosis at any given time.","definition_xrefs":["PomBase:mah","PMID:11683392","PMID:22684255"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell population phenotype","termid":"FYPO:0000003"},{"relation_name":"is_a","term_name":"abnormal phenotype","termid":"FYPO:0001985"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000003"],"is_obsolete":false,"name":"increased mitotic index","termid":"FYPO:0003307"}


id: PBO:0080015
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin specific peptidase 17 like family member 1","termid":"PBO:0080015"}


id: GO:0047841
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2-dehydro-D-gluconate + ATP = 6-phospho-2-dehydro-D-gluconate + ADP + 2 H+.","definition_xrefs":["EC:2.7.1.13","RHEA:10788"],"direct_ancestors":[{"relation_name":"is_a","term_name":"kinase activity","termid":"GO:0016301"},{"relation_name":"is_a","term_name":"phosphotransferase activity, alcohol group as acceptor","termid":"GO:0016773"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016301"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0016301","GO:0016740","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"dehydrogluconokinase activity","secondary_identifiers":["KEGG_REACTION:R02658","MetaCyc:DEHYDOGLUCONOKINASE-RXN"],"synonyms":[{"name":"2-ketogluconate kinase activity","type":"related"},{"name":"2-ketogluconokinase activity","type":"related"},{"name":"ATP:2-dehydro-D-gluconate 6-phosphotransferase activity","type":"related"},{"name":"dehydogluconokinase activity","type":"exact"},{"name":"ketogluconokinase (phosphorylating)","type":"related"},{"name":"ketogluconokinase activity","type":"related"}],"termid":"GO:0047841"}


id: GO:0043434
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.","definition_xrefs":["PMID:15134857","Wikipedia:Peptide_hormone","PMID:11027914"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to hormone","termid":"GO:0009725"},{"relation_name":"is_a","term_name":"response to nitrogen compound","termid":"GO:1901698"},{"relation_name":"is_a","term_name":"response to oxygen-containing compound","termid":"GO:1901700"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to peptide hormone","synonyms":[{"name":"response to peptide hormone stimulus","type":"exact"},{"name":"response to polypeptide hormone stimulus","type":"exact"}],"termid":"GO:0043434"}


id: PBO:0054157
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1524","termid":"PBO:0054157"}


id: MONDO:0014892
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"autosomal dominant non-syndromic intellectual disability","termid":"MONDO:0015802"},{"relation_name":"is_a","term_name":"congenital nervous system disorder","termid":"MONDO:0002320"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"},{"relation_name":"is_a","term_name":"autosomal dominant syndromic intellectual disability","termid":"MONDO:0100601"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"},{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0002320","MONDO:0000426"],"is_obsolete":false,"name":"micrognathia-recurrent infections-behavioral abnormalities-mild intellectual disability syndrome","secondary_identifiers":["Orphanet:476126","UMLS:C4310740","GARD:17850","MEDGEN:934707","DOID:0070074","OMIM:617061"],"synonyms":[{"name":"MEBAS","type":"exact"},{"name":"MRD44","type":"exact"},{"name":"autosomal dominant intellectual disability 44","type":"exact"},{"name":"autosomal dominant mental retardation 44","type":"exact"},{"name":"autosomal dominant non-syndromic intellectual disability 44","type":"related"},{"name":"intellectual developmental disorder, autosomal dominant 44, with microcephaly","type":"exact"},{"name":"intellectual disability, autosomal dominant 44","type":"related"},{"name":"mental retardation, autosomal dominant 44","type":"related"},{"name":"mercer-Ba syndrome","type":"exact"}],"termid":"MONDO:0014892","xrefs":{"Monarch":{"xref_id":"0014892"}}}


id: GO:0006337
data:
  {"annotated_genes":["SJAG_04038","SJAG_01653","SJAG_02314"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[91877,98896,118764],"is_not":false,"summary":null,"term":"GO:0006337"}]},"cv_name":"biological_process","definition":"The controlled breakdown of nucleosomes, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-DNA complex disassembly","termid":"GO:0032986"},{"relation_name":"is_a","term_name":"nucleosome organization","termid":"GO:0034728"}],"gene_count":3,"genes_by_uniquename":{"SJAG_01653":null,"SJAG_02314":null,"SJAG_04038":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006325"}],"interesting_parent_ids":["GO:0008150","GO:0006325"],"is_obsolete":false,"name":"nucleosome disassembly","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0006337","terms_by_termid":{"GO:0006337":null}}


id: PBO:0034046
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-in_similarity_relationship_with","termid":"PBO:0034046"}


id: MONDO:0007997
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microspherophakia with hernia","secondary_identifiers":["OMIM:157150","MESH:C537468","UMLS:C1834881","MEDGEN:322521"],"synonyms":[{"name":"microspherophakia with hernia","type":"exact"}],"termid":"MONDO:0007997","xrefs":{"Monarch":{"xref_id":"0007997"}}}


id: MONDO:1010008
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Atherosclerosis that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cardiovascular disorder, non-human animal","termid":"MONDO:1011306"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"atherosclerosis, non-human animal","secondary_identifiers":["OMIA:000080"],"termid":"MONDO:1010008","xrefs":{"Monarch":{"xref_id":"1010008"}}}


id: GO:1990117
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"An extrinsic apoptotic signaling pathway initiated by the cross-linking of an antigen receptor on a B cell.","definition_xrefs":["PMID:15214043","GOC:mtg_apoptosis","GOC:BHF","GOC:rl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"B cell receptor signaling pathway","termid":"GO:0050853"},{"relation_name":"is_a","term_name":"extrinsic apoptotic signaling pathway","termid":"GO:0097191"},{"relation_name":"part_of","term_name":"B cell apoptotic process","termid":"GO:0001783"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"B cell receptor apoptotic signaling pathway","synonyms":[{"name":"B cell receptor extrinsic apoptotic signaling pathway","type":"exact"},{"name":"extrinsic apoptotic signaling pathway via B cell antigen receptor","type":"related"},{"name":"extrinsic apoptotic signaling pathway via BCR","type":"related"}],"termid":"GO:1990117"}


id: PBO:0080181
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"VDAC2 pseudogene 2","termid":"PBO:0080181"}


id: GO:0006051
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose.","definition_xrefs":["GOC:ai","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mannosamine metabolic process","termid":"GO:0006050"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"N-acetylmannosamine metabolic process","synonyms":[{"name":"N-acetylmannosamine metabolism","type":"exact"}],"termid":"GO:0006051"}


id: PBO:0040241
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"autophagy related 2A","termid":"PBO:0040241"}


id: GO:0031224
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. The component of a membrane consisting of the gene products having some covalently attached portion, for example part of a peptide sequence or some other covalently attached group such as a GPI anchor, which spans or is embedded in one or both leaflets of the membrane.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete intrinsic component of membrane (obsolete GO:0031224)","synonyms":[{"name":"intrinsic to membrane","type":"narrow"}],"termid":"GO:0031224"}


id: PBO:0084570
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Membrane protein involved in zinc ion homeostasis; member of the four-protein IZH family, expression induced by zinc deficiency; deletion reduces sensitivity to elevated zinc and shortens lag phase, overexpression reduces Zap1p activity","termid":"PBO:0084570"}


id: PBO:0003179
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"G2/M B-type cyclin Cdc13","termid":"PBO:0003179"}


id: GO:0034781
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: N-cyclohexylformamide + OH- = cyclohexylamine + formate.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete N-cyclohexylformamide amidohydrolase activity (obsolete GO:0034781)","termid":"GO:0034781"}


id: GO:0044303
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"Any of the smaller branches of an axon that emanate from the main axon cylinder.","definition_xrefs":["NIF_Subcellular:sao1470140754"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"axon","termid":"GO:0030424"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"axon collateral","termid":"GO:0044303"}


id: PBO:0004700
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MCM complex subunit Mcm6","termid":"PBO:0004700"}


id: PBO:0015658
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nuclear 3'-tRNA processing endonuclease tRNAse Z, Trz1","termid":"PBO:0015658"}


id: PBO:0091716
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Multistep PhosphoRelay","termid":"PBO:0091716"}


id: PBO:0050276
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HMG-box containing 3","termid":"PBO:0050276"}


id: PR:Q1MTR2
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An RNA-binding protein with serine-rich domain 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR15481:SF0","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA-binding protein with serine-rich domain 1 homolog (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC13G1.14c","secondary_identifiers":["UniProtKB:Q1MTR2"],"synonyms":[{"name":"Spom972h-RNPS1","type":"exact"}],"termid":"PR:Q1MTR2"}


id: PR:O14329
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- zrg17 gene.","definition_xrefs":["UniProtKB:O14329","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc transporter zrg17 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC16E9.14c","synonyms":[{"name":"Spom972h-zrg17","type":"exact"}],"termid":"PR:O14329"}


id: FYPO:0003140
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of tyrosine residues in one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to heat.","definition_xrefs":["PomBase:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete decreased protein tyrosine phosphorylation during cellular response to heat (obsolete FYPO:0003140)","synonyms":[{"name":"decreased peptidyl-tyrosine phosphorylation during cellular response to heat","type":"exact"},{"name":"decreased protein tyrosine phosphorylation during cellular response to heat during mitotic cell cycle","type":"related"},{"name":"decreased protein tyrosine phosphorylation during cellular response to heat during vegetative growth","type":"exact"},{"name":"decreased tyrosine phosphorylation during cellular response to heat","type":"exact"},{"name":"reduced protein tyrosine phosphorylation during cellular response to heat","type":"exact"}],"termid":"FYPO:0003140"}


id: MONDO:0017868
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare, genetic, non-syndromic cerebral malformation characterized by severe intellectual disability, progressive postnatal microcephaly, axial hypotonia, spastic quadriparesis, seizures and facial dysmorphism (bushy eyebrows, hairy forehead, broad nasal root, long flat philtrum, V-shaped upper lip). Additionally, talipes equinovarus, non-obstructive cardiomyopathy, persistent hyperplastic primary vitreous, obstructive hydrocephalus and autistic features may also be associated. On brain magnetic resonance imaging, the 'butterfly sign' is characterisitcally observed and cortical calcifications, agenesis of the corpus callosum, ventriculomegaly, brainstem dysplasia and cerebellar vermis hypoplasia have also been described.","definition_xrefs":["Orphanet:319192"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"disorder of development or morphogenesis","termid":"MONDO:0021147"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"diencephalic-mesencephalic junction dysplasia","secondary_identifiers":["UMLS:C4707858","GARD:21407","MEDGEN:1641855","OMIMPS:251280"],"synonyms":[{"name":"diencephalic-mesencephalic junction dysplasia syndrome","type":"exact"}],"termid":"MONDO:0017868","xrefs":{"Monarch":{"xref_id":"0017868"}}}


id: PBO:0059948
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-ND2 pseudogene 34","termid":"PBO:0059948"}


id: PBO:0078530
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tripartite motif containing 23","termid":"PBO:0078530"}


id: MONDO:0100047
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An inherited susceptibility or predisposition to developing basal cell carcinoma.","definition_xrefs":["MONDO:patterns/inherited_susceptibility"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inherited disease susceptibility","termid":"MONDO:0020573"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"basal cell carcinoma, susceptibility to","termid":"MONDO:0100047","xrefs":{"Monarch":{"xref_id":"0100047"}}}


id: PBO:0071278
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RPL26L1 antisense RNA 1","termid":"PBO:0071278"}


id: PBO:0000172
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin-protein ligase E3 Rad8","termid":"PBO:0000172"}


id: MONDO:0005402
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A malignant lymphocytic neoplasm of B-cell or T-cell lineage involving primarily the bone marrow and the peripheral blood. This category includes precursor or acute lymphoblastic leukemias and chronic leukemias.","definition_xrefs":["NCIT:C7539"],"direct_ancestors":[{"relation_name":"is_a","term_name":"leukemia","termid":"MONDO:0005059"},{"relation_name":"is_a","term_name":"lymphoid neoplasm","termid":"MONDO:0005157"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"lymphoid leukemia","secondary_identifiers":["ICD9:204.20","ICDO:9820/3","DOID:1037","ICD10CM:C91","DOID:10747","ICD9:204.2","HP:0005526","MESH:D007945","UMLS:C0023448","ICDO:981-983","ICD9:204","MEDGEN:9728","SCTID:188726003","EFO:0004289"],"synonyms":[{"name":"leukemia, LYMPHOCYTIC, malignant","type":"exact"},{"name":"lymphocytic leukaemia","type":"exact"},{"name":"lymphocytic leukemia","type":"exact"},{"name":"lymphogenous leukaemia","type":"exact"},{"name":"lymphogenous leukemia","type":"exact"},{"name":"lymphoid leukaemia (disease)","type":"exact"},{"name":"lymphoid leukemia","type":"exact"},{"name":"lymphoid leukemia (disease)","type":"exact"},{"name":"subacute lymphoid leukaemia","type":"exact"},{"name":"subacute lymphoid leukemia","type":"exact"}],"termid":"MONDO:0005402","xrefs":{"Monarch":{"xref_id":"0005402"}}}


id: MONDO:0019219
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"inborn disorder of biogenic amine metabolism and transport","termid":"MONDO:0019250"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066"],"is_obsolete":false,"name":"inborn disorder of neurotransmitter metabolism and transport","secondary_identifiers":["MEDGEN:1842206","UMLS:C5681289","Orphanet:79169","GARD:18950"],"synonyms":[{"name":"disorder of neurotransmitter metabolism and transport","type":"related"}],"termid":"MONDO:0019219","xrefs":{"Monarch":{"xref_id":"0019219"}}}


id: PBO:0050612
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hydroxysteroid 17-beta dehydrogenase 4","termid":"PBO:0050612"}


id: GO:0043865
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of methionine from one side of a membrane to the other.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sulfur amino acid transmembrane transporter activity","termid":"GO:0000099"},{"relation_name":"is_a","term_name":"organic cation transmembrane transporter activity","termid":"GO:0015101"},{"relation_name":"is_a","term_name":"amino acid transmembrane transporter activity","termid":"GO:0015171"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0022857","GO:0003674","GO:0005215"],"is_obsolete":false,"name":"methionine transmembrane transporter activity","secondary_identifiers":["GO:1990240"],"synonyms":[{"name":"methionine importer","type":"related"},{"name":"methionine importer activity","type":"narrow"},{"name":"methionine importing activity","type":"narrow"},{"name":"methionine-importing activity","type":"narrow"}],"termid":"GO:0043865"}


id: PBO:0078460
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T cell receptor gamma variable A (pseudogene)","termid":"PBO:0078460"}


id: PBO:0067116
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 160, pseudogene","termid":"PBO:0067116"}


id: PBO:0003159
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3.5.4.6","termid":"PBO:0003159"}


id: PBO:0046666
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"epithelial splicing regulatory protein 1","termid":"PBO:0046666"}


id: MONDO:0030692
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"immunodeficiency disease","termid":"MONDO:0021094"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"immunodeficiency 95","secondary_identifiers":["MEDGEN:1802205","OMIM:619773","UMLS:C5676929"],"synonyms":[{"name":"IMD95","type":"exact"},{"name":"immunodeficiency 95","type":"exact"}],"termid":"MONDO:0030692","xrefs":{"Monarch":{"xref_id":"0030692"}}}


id: PBO:0082164
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Adenylosuccinate lyase; catalyzes two steps in the 'de novo' purine nucleotide biosynthetic pathway; expression is repressed by adenine and activated by Bas1p and Pho2p; mutations in human ortholog ADSL cause adenylosuccinase deficiency; human ADSL can complement yeast ADE13 null mutant","termid":"PBO:0082164"}


id: PBO:0083924
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Fructose 1,6-bisphosphate aldolase; required for glycolysis and gluconeogenesis; catalyzes conversion of fructose 1,6 bisphosphate to glyceraldehyde-3-P and dihydroxyacetone-P; locates to mitochondrial outer surface upon oxidative stress; N-terminally propionylated in vivo","termid":"PBO:0083924"}


id: PBO:0074696
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, H/ACA box 70F","termid":"PBO:0074696"}


id: MONDO:0600025
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Fluid accumulation and dilatation of the fallopian tube due to tubal blockage.","definition_xrefs":["PMID:30824209","NCIT:C142886"],"direct_ancestors":[{"relation_name":"is_a","term_name":"fallopian tube disorder","termid":"MONDO:0002156"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hydrosalpinx","secondary_identifiers":["UMLS:C0221376","MEDGEN:526227","icd11.foundation:1766606192"],"synonyms":[{"name":"blocked fallopian tube","type":"exact"},{"name":"fallopian tube obstruction","type":"exact"}],"termid":"MONDO:0600025","xrefs":{"Monarch":{"xref_id":"0600025"}}}


id: SO:0001461
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A binding site that, in the enhancer region of a nucleotide molecule, interacts selectively and non-covalently with polypeptide residues.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleotide_to_protein_binding_site","termid":"SO:0001654"},{"relation_name":"part_of","term_name":"enhancer","termid":"SO:0000165"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"enhancer_binding_site","synonyms":[{"name":"enhancer binding site","type":"related"}],"termid":"SO:0001461"}


id: MOD:00611
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that is produced by reaction of iodouridine monophosphate with a residue.","definition_xrefs":["PubMed:11112526","PubMed:6540775","Unimod:292","PubMed:11567090"],"direct_ancestors":[{"relation_name":"is_a","term_name":"reagent derivatized residue","termid":"MOD:00848"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"iodouridine monophosphate derivatized residue","synonyms":[{"name":"Cross-link of (Iodo)-uracil MP with W,F,Y","type":"related"},{"name":"IodoU-AMP","type":"related"}],"termid":"MOD:00611"}


id: PBO:0054406
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1802","termid":"PBO:0054406"}


id: GO:1904745
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The aggregation, arrangement and bonding together of a set of components to form an Atg1/UKL1 kinase complex.","definition_xrefs":["GOC:dph","PMID:25139988","GO_REF:0000079","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex assembly","termid":"GO:0065003"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0065003"}],"interesting_parent_ids":["GO:0008150","GO:0065003","GO:0044085"],"is_obsolete":false,"name":"Atg1/ULK1 kinase complex assembly","synonyms":[{"name":"ATG1 kinase complex assembly","type":"exact"},{"name":"ATG1 kinase complex formation","type":"exact"},{"name":"ATG1-ATG13 complex assembly","type":"exact"},{"name":"ATG1-ATG13 complex formation","type":"exact"},{"name":"ATG1/ULK1 kinase complex formation","type":"exact"},{"name":"ATG1/ULK1 signaling complex assembly","type":"exact"},{"name":"ATG1/ULK1 signaling complex formation","type":"exact"},{"name":"Atg1p signalling complex assembly","type":"exact"},{"name":"Atg1p signalling complex formation","type":"exact"},{"name":"ULK1 signaling complex assembly","type":"exact"},{"name":"ULK1 signaling complex formation","type":"exact"},{"name":"ULK1-ATG13-FIP200 complex assembly","type":"exact"},{"name":"ULK1-ATG13-FIP200 complex formation","type":"exact"},{"name":"ULK1-ATG13-RB1CC1 complex assembly","type":"exact"},{"name":"ULK1-ATG13-RB1CC1 complex formation","type":"exact"}],"termid":"GO:1904745"}


id: PBO:0055999
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"LSM1 homolog, mRNA degradation associated pseudogene 2","termid":"PBO:0055999"}


id: PBO:0069179
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 433, pseudogene","termid":"PBO:0069179"}


id: PBO:0089199
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytidine deaminase Ccd1","termid":"PBO:0089199"}


id: PBO:0067583
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 741, pseudogene","termid":"PBO:0067583"}


id: MONDO:0000456
data:
  {"annotated_genes":["SJAG_02271"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87242],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012999"}]},"cv_name":"mondo","definition":"Creatine deficiency syndrome (CDS) comprises a group of inborn errors of creatine metabolism, characterized by a global developmental delay, intellectual disability and associated neurological (seizures, movement disorders, myopathy) and behavioral manifestions. CDS includes two creatine biosynthesis disorders; guanidinoacetate methyltransferase deficiency and L- Arginine: glycine amidinotransferase deficiency, as well as X-linked creatine transporter deficiency.","definition_xrefs":["Orphanet:79172"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"metabolic epilepsy","termid":"MONDO:0100033"},{"relation_name":"is_a","term_name":"inborn disorder of amino acid metabolism","termid":"MONDO:0004736"},{"relation_name":"is_a","term_name":"inborn disorder of amino acid and other organic acid metabolism","termid":"MONDO:0019189"},{"relation_name":"is_a","term_name":"inborn disorder of energy metabolism","termid":"MONDO:0019243"},{"relation_name":"is_a","term_name":"disorder of organic acid metabolism","termid":"MONDO:0045022"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02271":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004736"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0004736"],"is_obsolete":false,"name":"cerebral creatine deficiency syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["NANDO:1201032","MEDGEN:1826001","GARD:18952","DOID:0050798","OMIMPS:300352","NANDO:2200842","UMLS:C5244016","NANDO:2100226"],"synonyms":[{"name":"CCDS","type":"exact"},{"name":"CDS","type":"exact"},{"name":"cerebral creatine deficiency syndrome","type":"exact"},{"name":"creatine deficiency syndrome","type":"exact"}],"termid":"MONDO:0000456","terms_by_termid":{"MONDO:0012999":null},"xrefs":{"Monarch":{"xref_id":"0000456"}}}


id: PBO:0045027
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease","termid":"PBO:0045027"}


id: PBO:0030980
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_histone_H3-K9_trimethylation_at_centromere_inner_repeat","termid":"PBO:0030980"}


id: MONDO:0017211
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"panuveitis","termid":"MONDO:0017255"},{"relation_name":"is_a","term_name":"eye infectious disorder","termid":"MONDO:0043885"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"infectious panuveitis","secondary_identifiers":["Orphanet:279925","UMLS:C5230354","MEDGEN:1684863","GARD:21068","icd11.foundation:1709165622"],"termid":"MONDO:0017211","xrefs":{"Monarch":{"xref_id":"0017211"}}}


id: PR:Q9US22
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- rpl1502 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9US22"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"60S ribosomal protein L15-B (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1783.08c","synonyms":[{"name":"Spom972h-rpl1502","type":"exact"}],"termid":"PR:Q9US22"}


id: MONDO:0017180
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"partial duplication of the long arm of chromosome 10","termid":"MONDO:0016961"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"10q22.3q23.3 microduplication syndrome","secondary_identifiers":["GARD:21052","MEDGEN:1682781","Orphanet:276422","UMLS:C5190512"],"synonyms":[{"name":"dup(10)(q22.3q23.3)","type":"exact"},{"name":"trisomy 10q22.3q23.3","type":"exact"}],"termid":"MONDO:0017180","xrefs":{"Monarch":{"xref_id":"0017180"}}}


id: PBO:0058058
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4279","termid":"PBO:0058058"}


id: PBO:0076186
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SUMO1 pseudogene 1","termid":"PBO:0076186"}


id: PBO:0073483
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sphingomyelin synthase 1","termid":"PBO:0073483"}


id: PBO:0082664
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of the conserved oligomeric Golgi complex; a cytosolic tethering complex (Cog1p through Cog8p) that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments","termid":"PBO:0082664"}


id: GO:1905190
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiosis II.","definition_xrefs":["PMID:21389117","GO_REF:0000058","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of metaphase/anaphase transition of meiotic cell cycle","termid":"GO:1902103"},{"relation_name":"is_a","term_name":"regulation of metaphase/anaphase transition of meiosis II","termid":"GO:1905189"},{"relation_name":"negatively_regulates","term_name":"metaphase/anaphase transition of meiosis II","termid":"GO:1990950"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0007049","GO:0008150"],"is_obsolete":false,"name":"negative regulation of metaphase/anaphase transition of meiosis II","synonyms":[{"name":"negative regulation of meiosis II metaphase/anaphase transition","type":"exact"}],"termid":"GO:1905190"}


id: FYPO:0005315
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of negative regulation of transcription at the central core of the centromeric regions is increased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal chromatin silencing at centromere central core","termid":"FYPO:0000640"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0006551","FYPO:0005447","FYPO:0001320"],"is_obsolete":false,"name":"increased chromatin silencing at centromere central core","synonyms":[{"name":"increased chromatin silencing at centromere central core during mitotic cell cycle","type":"related"},{"name":"increased chromatin silencing at centromere central core during vegetative growth","type":"exact"},{"name":"increased negative regulation of transcription at centromere central core","type":"related"},{"name":"increased transcriptional repression at centromere central core","type":"related"}],"termid":"FYPO:0005315"}


id: GO:0106316
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: NH4+ + 3 NAD+ + 2 H2O = nitrite + 3 NADH + 5 H+.","definition_xrefs":["RHEA:24628"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nitrite reductase [NAD(P)H] activity","termid":"GO:0008942"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"nitrite reductase (NADH) activity","secondary_identifiers":["EC:1.7.1.15"],"termid":"GO:0106316"}


id: PBO:0030048
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_ferric_iron_import","termid":"PBO:0030048"}


id: PBO:0067226
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 296, pseudogene","termid":"PBO:0067226"}


id: FYPO:0007765
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A gene expression phenotype in which protein levels that normally vary over the course of the mitotic cell cycle do not vary, or change in a pattern different from normal. Total protein or a specific protein may be affected.","definition_xrefs":["PomBase:mah","PMID:9430640"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gene expression regulation phenotype during vegetative growth","termid":"FYPO:0001333"},{"relation_name":"is_a","term_name":"abnormal phenotype","termid":"FYPO:0001985"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"abnormal protein level oscillation during mitotic cell cycle","synonyms":[{"name":"abnormal periodic protein expression during mitotic cell cycle","type":"exact"},{"name":"abnormal protein level fluctuation during mitotic cell cycle","type":"exact"}],"termid":"FYPO:0007765"}


id: PBO:0002477
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA replication factor C complex subunit Rfc2","termid":"PBO:0002477"}


id: PBO:0085810
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein of unknown function; epitope-tagged protein localizes to the cytoplasm; YKR074W is not an essential gene; null mutant displays elevated frequency of mitochondrial genome loss","termid":"PBO:0085810"}


id: PBO:0073584
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"shieldin complex subunit 2","termid":"PBO:0073584"}


id: PBO:0088314
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bromodomain protein Bdc1","termid":"PBO:0088314"}


id: MONDO:0016341
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete lysosomal disease with restrictive cardiomyopathy (obsolete MONDO:0016341)","secondary_identifiers":["Orphanet:217638"],"termid":"MONDO:0016341","xrefs":{"Monarch":{"xref_id":"0016341"}}}


id: PR:P0CT61
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- rpl2302 gene.","definition_xrefs":["UniProtKB:P0CT61","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"60S ribosomal protein L23-B (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC1322.11","synonyms":[{"name":"Spom972h-rpl2302","type":"exact"}],"termid":"PR:P0CT61"}


id: PBO:0041281
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"C1q and TNF related 7","termid":"PBO:0041281"}


id: FYPO:0007624
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitochondrial cytochrome c oxidase (respiratory chain complex IV) assembly is decreased.","definition_xrefs":["GO:0033617","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased mitochondrial respiratory chain complex assembly","termid":"FYPO:0007122"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001985","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"decreased mitochondrial respiratory chain complex IV assembly","synonyms":[{"name":"decreased mitochondrial cytochrome c oxidase assembly","type":"exact"},{"name":"decreased mitochondrial respiratory chain complex IV assembly during mitotic cell cycle","type":"related"},{"name":"decreased mitochondrial respiratory chain complex IV assembly during vegetative growth","type":"exact"},{"name":"decreased respiratory chain complex IV assembly","type":"exact"}],"termid":"FYPO:0007624"}


id: GO:0120125
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex responsible for the catalysis of the reaction: 4-N-(N-acetyl-D-glucosaminyl)-protein + H2O = N-acetyl-beta-D-glucosaminylamine + peptide L-aspartate. This reaction is the hydrolysis of an N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the N-acetyl-D-glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and the peptide containing an aspartic residue.","definition_xrefs":["GOC:lnp","PMID:15964983","PMID:16249333"],"direct_ancestors":[{"relation_name":"is_a","term_name":"peptidase complex","termid":"GO:1905368"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"PNGase complex","termid":"GO:0120125"}


id: FYPO:0006285
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the duration of localization of a protein to the telomere of a chromosome is longer than normal during anaphase B of mitosis.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased duration of protein localization to telomere","termid":"FYPO:0005649"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000138"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0005447","FYPO:0000002","FYPO:0001320","FYPO:0001985"],"is_obsolete":false,"name":"increased duration of protein localization to telomere during mitotic anaphase B","synonyms":[{"name":"increased duration of protein localisation to telomere during mitotic anaphase B","type":"exact"},{"name":"increased duration of protein localization to chromosome, telomeric region during mitotic anaphase B","type":"exact"},{"name":"increased duration of protein localization to telomere during anaphase B during vegetative growth","type":"exact"},{"name":"increased duration of protein localization to telomere during anaphase B of mitotic cell cycle","type":"exact"},{"name":"increased duration of protein localization to telomeric region during mitotic anaphase B","type":"exact"},{"name":"prolonged protein localization to telomere during mitotic anaphase B","type":"exact"}],"termid":"FYPO:0006285"}


id: MONDO:0013227
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Congenital plasminogen activator inhibitor type 1 (PAI-1) deficiency is a rare genetic bleeding disorder characterized by premature lysis of hemostatic clots and a moderate bleeding tendency.","definition_xrefs":["Orphanet:465"],"direct_ancestors":[{"relation_name":"is_a","term_name":"coagulation protein disease","termid":"MONDO:0002242"},{"relation_name":"is_a","term_name":"hemorrhagic disease","termid":"MONDO:0002243"},{"relation_name":"is_a","term_name":"congenital hematological disorder","termid":"MONDO:0009332"},{"relation_name":"is_a","term_name":"inherited blood coagulation disorder","termid":"MONDO:0021181"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"congenital plasminogen activator inhibitor type 1 deficiency","secondary_identifiers":["NCIT:C133884","SCTID:717407006","MESH:C567640","MEDGEN:412870","icd11.foundation:428643962","UMLS:C2750067","GARD:4381","OMIM:613329","NANDO:2200688"],"synonyms":[{"name":"congenital PAI-1 deficiency","type":"exact"},{"name":"congenital plasminogen activator inhibitor type 1 deficiency","type":"exact"},{"name":"hyperfibrinolysis due to Pai1 deficiency","type":"related"},{"name":"plasminogen activator INHIBITOR-1 deficiency","type":"related"},{"name":"plasminogen activator inhibitor type 1 deficiency","type":"related"}],"termid":"MONDO:0013227","xrefs":{"Monarch":{"xref_id":"0013227"}}}


id: PBO:0054467
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1866","termid":"PBO:0054467"}


id: PR:Q10414
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A CWF19-like protein 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO00248","PRO:DNx","PANTHER:PTHR12072:SF3"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CWF19-like protein mug161 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1F3.09","secondary_identifiers":["UniProtKB:Q10414"],"synonyms":[{"name":"Spom972h-CWF19L1","type":"exact"},{"name":"meiotically up-regulated gene 161 protein (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q10414"}


id: MONDO:0957580
data:
  {"annotated_genes":["SJAG_04887"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88169],"is_not":false,"summary":null,"term":"MONDO:0957580"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"inherited bleeding disorder, platelet-type","termid":"MONDO:0000009"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04887":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"bleeding disorder, platelet-type, 25","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C5882683","OMIM:620486","MEDGEN:1846290"],"termid":"MONDO:0957580","terms_by_termid":{"MONDO:0957580":null},"xrefs":{"Monarch":{"xref_id":"0957580"}}}


id: GO:0008162
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete cyclodiene resistance (obsolete GO:0008162)","synonyms":[{"name":"cyclodiene resistance","type":"exact"}],"termid":"GO:0008162"}


id: MONDO:0010251
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"non-syndromic X-linked intellectual disability","termid":"MONDO:0019181"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"intellectual disability, X-linked 50","secondary_identifiers":["OMIM:300115","MEDGEN:376278","UMLS:C1848087","DOID:0112029","GARD:22668","MESH:C564713"],"synonyms":[{"name":"MRX50","type":"exact"},{"name":"intellectual developmental disorder, X-linked 50","type":"exact"},{"name":"intellectual disability, X-linked 50","type":"exact"},{"name":"mental retardation, X-linked 50","type":"related"}],"termid":"MONDO:0010251","xrefs":{"Monarch":{"xref_id":"0010251"}}}


id: PBO:0082629
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of CORVET membrane tethering complex; vacuolar peripheral membrane protein that promotes vesicular docking/fusion reactions in conjunction with SNARE proteins, required for vacuolar biogenesis","termid":"PBO:0082629"}


id: PBO:0069799
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1085, pseudogene","termid":"PBO:0069799"}


id: PBO:0067369
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 470, pseudogene","termid":"PBO:0067369"}


id: MONDO:0005851
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An autoimmune process characterized by the clinical triad of ophthalmoplegia, ataxia, and areflexia.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autoimmune disorder of central nervous system","termid":"MONDO:0000568"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"cerebellar disorder","termid":"MONDO:0002427"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"Miller Fisher syndrome","secondary_identifiers":["MESH:D019846","icd11.foundation:134795253","MedDRA:10049567","EFO:0007371","MEDGEN:95994","Orphanet:98919","SCTID:1767005","NCIT:C116958","UMLS:C0393799","DOID:12889","GARD:3668"],"synonyms":[{"name":"Fisher syndrome","type":"exact"},{"name":"Fisher's syndrome","type":"exact"},{"name":"Guillain Barre syndrome, Miller Fisher variant","type":"exact"},{"name":"Guillain-Barre syndrome, Miller Fisher variant","type":"exact"},{"name":"Miller Fisher variant of Guillain Barre syndrome","type":"exact"},{"name":"Miller-Fisher syndrome","type":"exact"},{"name":"Miller-Fisher variant of Guillain-Barre syndrome","type":"exact"},{"name":"cranial variant of GBS","type":"exact"},{"name":"cranial variant of Guillain-Barre syndrome","type":"exact"},{"name":"cranial variant of Guillain-Barré syndrome","type":"exact"},{"name":"ophthalmoplegia, ataxia and areflexia syndrome","type":"exact"},{"name":"syndrome, Fisher","type":"exact"},{"name":"syndrome, Miller Fisher","type":"exact"},{"name":"syndrome, Miller-Fisher","type":"exact"}],"termid":"MONDO:0005851","xrefs":{"Monarch":{"xref_id":"0005851"}}}


id: PBO:0089595
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"histone H2A-H2B chaperone, FACT complex subunit Spt16","termid":"PBO:0089595"}


id: MONDO:0002084
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete neuroectodermal tumor (obsolete MONDO:0002084)","termid":"MONDO:0002084","xrefs":{"Monarch":{"xref_id":"0002084"}}}


id: PBO:0039870
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ARHGAP28 antisense RNA 1","termid":"PBO:0039870"}


id: PBO:0047461
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Fc receptor like 2","termid":"PBO:0047461"}


id: MONDO:0016556
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"transient congenital hypothyroidism","termid":"MONDO:0015792"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transient congenital hypothyroidism due to neonatal factor","secondary_identifiers":["UMLS:C5680930","GARD:20646","MEDGEN:1842815","Orphanet:238699"],"termid":"MONDO:0016556","xrefs":{"Monarch":{"xref_id":"0016556"}}}


id: MONDO:0800349
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"familial atrial fibrillation","termid":"MONDO:0018054"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"atrial fibrillation, familial, 16","secondary_identifiers":["UMLS:C4013699","MEDGEN:862136"],"synonyms":[{"name":"ATFB16","type":"exact"}],"termid":"MONDO:0800349","xrefs":{"Monarch":{"xref_id":"0800349"}}}


id: MONDO:0008578
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"toe, rotated fifth","secondary_identifiers":["UMLS:C1861060","OMIM:189150","MEDGEN:348254"],"synonyms":[{"name":"toe, rotated fifth","type":"exact"}],"termid":"MONDO:0008578","xrefs":{"Monarch":{"xref_id":"0008578"}}}


id: PBO:0028984
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_alpha,alpha-trehalase_activity_during_cellular_response_to_nutrient","termid":"PBO:0028984"}


id: PBO:0039227
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"AKT1 substrate 1","termid":"PBO:0039227"}


id: MONDO:0013582
data:
  {"annotated_genes":["SJAG_02795"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87712],"is_not":false,"summary":null,"term":"MONDO:0013582"}]},"cv_name":"mondo","definition":"Any mosaic variegated aneuploidy syndrome in which the cause of the disease is a mutation in the CEP57 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mosaic variegated aneuploidy syndrome","termid":"MONDO:0000141"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02795":null},"genotype_count":0,"is_obsolete":false,"name":"mosaic variegated aneuploidy syndrome 2","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["DOID:0080142","GARD:15758","NCIT:C168989","OMIM:614114","UMLS:C3279843","MEDGEN:481473"],"synonyms":[{"name":"CEP57 mosaic variegated aneuploidy syndrome","type":"exact"},{"name":"MOSAIC variegated aneuploidy syndrome 2","type":"related"},{"name":"MVA2","type":"related"},{"name":"Mosaic variegated aneuploidy syndrome type 2","type":"exact"},{"name":"mosaic variegated aneuploidy syndrome 2","type":"exact"},{"name":"mosaic variegated aneuploidy syndrome caused by mutation in CEP57","type":"exact"},{"name":"mosaic variegated aneuploidy syndrome type 2","type":"exact"}],"termid":"MONDO:0013582","terms_by_termid":{"MONDO:0013582":null},"xrefs":{"Monarch":{"xref_id":"0013582"}}}


id: GO:0045305
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Functions to either promote or inhibit the establishment of competence for transformation.","definition_xrefs":["GOC:mlg"],"gene_count":0,"genotype_count":0,"name":"obsolete regulator of establishment of competence for transformation activity (obsolete GO:0045305)","synonyms":[{"name":"regulator of establishment of competence for transformation activity","type":"exact"}],"termid":"GO:0045305"}


id: PR:O94427
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPBC660.08 gene.","definition_xrefs":["UniProtKB:O94427","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiotically up-regulated gene 167 protein (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC660.08","synonyms":[{"name":"Spom972h-SPBC660.08","type":"exact"}],"termid":"PR:O94427"}


id: PBO:0079705
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquilin 1","termid":"PBO:0079705"}


id: PBO:0048461
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GTP cyclohydrolase 1","termid":"PBO:0048461"}


id: FYPO:0002889
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell morphology phenotype in which a vegetatively growing cell is inviable, is elongated, and contains one or more abnormal septa.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"has_part","term_name":"abnormal septum during vegetative growth","termid":"FYPO:0002455"},{"relation_name":"is_a","term_name":"inviable elongated vegetative cell","termid":"FYPO:0001490"},{"relation_name":"is_a","term_name":"abnormal septum during vegetative growth","termid":"FYPO:0002455"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"has_part","termid":"FYPO:0000004"},{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"has_part","termid":"FYPO:0000005"},{"rel_name":"is_a","termid":"FYPO:0000004"},{"rel_name":"has_part","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000005"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000005","FYPO:0000004","FYPO:0001985","FYPO:0001320"],"is_obsolete":false,"name":"inviable elongated vegetative cell with abnormal septum","synonyms":[{"name":"elongated inviable cell with abnormal septum","type":"exact"},{"name":"inviable elongated abnormally septated vegetative cell","type":"exact"},{"name":"inviable elongated cell with abnormal septum during vegetative growth","type":"exact"},{"name":"inviable elongated vegetative cell with abnormal septum during mitotic cell cycle","type":"related"},{"name":"lethal; elongated vegetative cell with abnormal septum","type":"exact"}],"termid":"FYPO:0002889"}


id: MONDO:0007965
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"familial melanoma","termid":"MONDO:0018961"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"melanoma, malignant familial intraocular","secondary_identifiers":["UMLS:C1835043","MEDGEN:322559","GARD:18576","MESH:C563596","OMIM:155700"],"synonyms":[{"name":"melanoma, malignant familial intraocular","type":"exact"}],"termid":"MONDO:0007965","xrefs":{"Monarch":{"xref_id":"0007965"}}}


id: PBO:0073788
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 5 member 8","termid":"PBO:0073788"}


id: GO:2000121
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of removal of superoxide radicals.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of superoxide metabolic process","termid":"GO:0090322"},{"relation_name":"is_a","term_name":"regulation of cellular response to oxidative stress","termid":"GO:1900407"},{"relation_name":"is_a","term_name":"regulation of response to reactive oxygen species","termid":"GO:1901031"},{"relation_name":"regulates","term_name":"removal of superoxide radicals","termid":"GO:0019430"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0098754"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0098754"],"is_obsolete":false,"name":"regulation of removal of superoxide radicals","synonyms":[{"name":"regulation of removal of O2-","type":"exact"},{"name":"regulation of removal of oxygen free radicals","type":"exact"}],"termid":"GO:2000121"}


id: PBO:0087763
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of TORC2 membrane-associated complex; involved in regulation of actin cytoskeletal dynamics during polarized growth and cell wall integrity; interacts with Slm1p and Slm2p, homologous PH domain-containing TORC2 substrates; BIT2 has a paralog, BIT61, that arose from the whole genome duplication","termid":"PBO:0087763"}


id: GO:0051344
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops or reduces the rate of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.","definition_xrefs":["GOC:tb","GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of hydrolase activity","termid":"GO:0051346"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of cyclic-nucleotide phosphodiesterase activity","synonyms":[{"name":"3',5' cyclic nucleotide phosphodiesterase inhibitor","type":"exact"},{"name":"3',5'-cyclic-AMP phosphodiesterase inhibitor","type":"narrow"},{"name":"cAMP phosphodiesterase inhibitor","type":"narrow"},{"name":"down regulation of cyclic nucleotide phosphodiesterase activity","type":"exact"},{"name":"down-regulation of cyclic nucleotide phosphodiesterase activity","type":"exact"},{"name":"downregulation of cyclic nucleotide phosphodiesterase activity","type":"exact"},{"name":"inhibition of cyclic nucleotide phosphodiesterase activity","type":"narrow"},{"name":"negative regulation of 3',5' cyclic nucleotide phosphodiesterase activity","type":"exact"},{"name":"negative regulation of 3',5'-cyclic-AMP phosphodiesterase activity","type":"narrow"},{"name":"negative regulation of cAMP phosphodiesterase activity","type":"narrow"},{"name":"negative regulation of cGMP phosphodiesterase activity","type":"narrow"},{"name":"negative regulation of cyclic nucleotide phosphodiesterase activity","type":"exact"},{"name":"phosphodiesterase inhibitor","type":"related"}],"termid":"GO:0051344"}


id: PBO:0073183
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"selenoprotein N","termid":"PBO:0073183"}


id: MONDO:0100432
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any immunodeficiency in which the cause of the disease is a mutation in the FNIP1 gene. Disruption of Folliculin Interacting Protein 1 alters the essential metabolic regulators AMPK and mTOR, resulting in profound B-cell deficiency, hypertrophic cardiomyopathy, and pre-excitation syndrome.","definition_xrefs":["PMID:32181500"],"direct_ancestors":[{"relation_name":"is_a","term_name":"immunodeficiency disease","termid":"MONDO:0021094"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"FNIP1-associated syndrome","synonyms":[{"name":"FNIP1 deficiency","type":"exact"},{"name":"absent B cells, agammaglobulinemia, and hypertrophic cardiomyopathy syndrome","type":"exact"},{"name":"immunodeficiency with cardiomyopathy and pre-excitation syndrome","type":"exact"}],"termid":"MONDO:0100432","xrefs":{"Monarch":{"xref_id":"0100432"}}}


id: GO:0046574
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the hydrolysis of glucuronosides, yielding free glucuronic acid.","definition_xrefs":["PMID:12044176","PMID:10441389"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, hydrolyzing O-glycosyl compounds","termid":"GO:0004553"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0016798"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016798","GO:0003824","GO:0016787","GO:0003674"],"is_obsolete":false,"name":"glycuronidase activity","synonyms":[{"name":"glucuronyl hydrolase activity","type":"exact"}],"termid":"GO:0046574"}


id: PBO:0027924
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_protein_aggregate_fusion","termid":"PBO:0027924"}


id: GO:0098838
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a folic acid, or one of its derivatives (dihydrofolate, tetrahydrofolate, methylene-tetrahydrofolate or methyl-tetrahydrofolate) is transported across a membrane.","definition_xrefs":["PMID:24745983"],"direct_ancestors":[{"relation_name":"is_a","term_name":"folic acid transport","termid":"GO:0015884"},{"relation_name":"is_a","term_name":"vitamin transmembrane transport","termid":"GO:0035461"},{"relation_name":"is_a","term_name":"carboxylic acid transmembrane transport","termid":"GO:1905039"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0051179","GO:0055085","GO:0006810"],"is_obsolete":false,"name":"folate transmembrane transport","synonyms":[{"name":"folic acid transmembrane transport","type":"related"},{"name":"reduced folate transmembrane transport","type":"narrow"}],"termid":"GO:0098838"}


id: GO:0010884
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.","definition_xrefs":["GOC:tb","GOC:BHF","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of lipid storage","termid":"GO:0010883"},{"relation_name":"is_a","term_name":"positive regulation of cellular process","termid":"GO:0048522"},{"relation_name":"is_a","term_name":"positive regulation of lipid localization","termid":"GO:1905954"},{"relation_name":"positively_regulates","term_name":"lipid storage","termid":"GO:0019915"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of lipid storage","synonyms":[{"name":"positive regulation of lipid sequestration","type":"narrow"}],"termid":"GO:0010884"}


id: GO:0061283
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the distal tubule of the mesonephric nephron acquires its identity.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"specification of mesonephric nephron tubule identity","termid":"GO:0061282"},{"relation_name":"is_a","term_name":"specification of distal tubule identity","termid":"GO:0072084"},{"relation_name":"part_of","term_name":"mesonephric distal tubule morphogenesis","termid":"GO:0061273"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"specification of mesonephric distal tubule identity","termid":"GO:0061283"}


id: PBO:0063848
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein inhibitor of activated STAT 1","termid":"PBO:0063848"}


id: GO:0102516
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside + 1-O-feruloyl-beta-D-glucose = delphinidin 3,7-di O-beta-D-glucoside + ferulate + H+.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete delphinidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity (obsolete GO:0102516)","termid":"GO:0102516"}


id: MONDO:0010866
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"This syndrome is characterized by osteopetrosis, agenesis of the corpus callosum, cerebral atrophy and a small hippocampus.","definition_xrefs":["Orphanet:85179"],"direct_ancestors":[{"relation_name":"is_a","term_name":"osteopetrosis","termid":"MONDO:0017198"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"infantile osteopetrosis with neuroaxonal dysplasia","secondary_identifiers":["SCTID:724226009","UMLS:C1838258","GARD:10082","OMIM:600329","DOID:0070343","icd11.foundation:1434293148","MESH:C536055","MEDGEN:373924"],"synonyms":[{"name":"osteopetrosis and infantile neuroaxonal dystrophy","type":"related"}],"termid":"MONDO:0010866","xrefs":{"Monarch":{"xref_id":"0010866"}}}


id: GO:1990408
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals initiated by an extracellular calcitonin gene-related peptide (CGRP) combining with a calcitonin gene-related peptide receptor on the surface of the target cell. Calcitonin gene-related peptide receptors may form dimers, trimers or tetramers.","definition_xrefs":["GOC:bhm","PMID:10882736"],"direct_ancestors":[{"relation_name":"is_a","term_name":"calcitonin family receptor signaling pathway","termid":"GO:0097646"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"calcitonin gene-related peptide receptor signaling pathway","synonyms":[{"name":"CGRP receptor signaling pathway","type":"exact"},{"name":"calcitonin-gene-related peptide receptor signaling pathway","type":"exact"},{"name":"calcitonin-gene-related polypeptide receptor signaling pathway","type":"exact"}],"termid":"GO:1990408"}


id: PR:O14190
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO00502"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UDP-N-acetylglucosamine transferase subunit alg13 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC56E4.02c","secondary_identifiers":["UniProtKB:O14190"],"synonyms":[{"name":"Spom972h-ALG13","type":"exact"},{"name":"asparagine-linked glycosylation protein 13 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O14190"}


id: GO:0047632
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: agmatine + H2O = N-carbamoylputrescine + NH3.","definition_xrefs":["EC:3.5.3.12","MetaCyc:AGMATINE-DEIMINASE-RXN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines","termid":"GO:0016813"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016810"}],"interesting_parent_ids":["GO:0003824","GO:0016787","GO:0003674","GO:0016810"],"is_obsolete":false,"name":"agmatine deiminase activity","secondary_identifiers":["RHEA:18037"],"synonyms":[{"name":"agmatine amidinohydrolase","type":"broad"},{"name":"agmatine iminohydrolase activity","type":"related"}],"termid":"GO:0047632"}


id: GO:0015797
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of mannitol across a membrane. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polyol transmembrane transport","termid":"GO:0015791"},{"relation_name":"is_a","term_name":"carbohydrate transmembrane transport","termid":"GO:0034219"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0051179","GO:0055085","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"mannitol transmembrane transport","synonyms":[{"name":"mannitol transport","type":"broad"}],"termid":"GO:0015797"}


id: GO:0021788
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube in response to an attractive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.","definition_xrefs":["GOC:dgh","GO_REF:0000021","PMID:14699587","GOC:dph","GOC:jid","GOC:cls"],"direct_ancestors":[{"relation_name":"is_a","term_name":"branchiomotor neuron axon guidance in neural tube","termid":"GO:0021786"},{"relation_name":"is_a","term_name":"chemoattraction of branchiomotor axon","termid":"GO:0021792"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"chemoattraction of branchiomotor neuron axon in neural tube","synonyms":[{"name":"positive chemotaxis of branchiomotor neuron axon in neural tube","type":"exact"}],"termid":"GO:0021788"}


id: MONDO:0008445
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"This syndrome is extremely rare and is characterized by delayed speech development, mild facial asymmetry, strabismus and transverse ear lobe creases.","definition_xrefs":["Orphanet:3038"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"delayed speech-facial asymmetry-strabismus-ear lobe creases syndrome","secondary_identifiers":["UMLS:C1866802","OMIM:182875","GARD:3449","MEDGEN:355803","SCTID:716199000"],"synonyms":[{"name":"Mehes syndrome","type":"exact"},{"name":"delayed speech development, facial asymmetry, strabismus, and transverse ear lobe creases","type":"related"},{"name":"speech development, delayed, with facial asymmetry, strabismus, and transverse earlobe CREASE","type":"related"}],"termid":"MONDO:0008445","xrefs":{"Monarch":{"xref_id":"0008445"}}}


id: MONDO:0015713
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete rare genetic endocrine disease (obsolete MONDO:0015513)","termid":"MONDO:0015513"},{"relation_name":"excluded_subClassOf","term_name":"obsolete anomaly of puberty or/and menstrual cycle of genetic origin (obsolete MONDO:0016072)","termid":"MONDO:0016072"},{"relation_name":"is_a","term_name":"central precocious puberty","termid":"MONDO:0019165"},{"relation_name":"is_a","term_name":"idiopathic disease","termid":"MONDO:0700007"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"idiopathic central precocious puberty","secondary_identifiers":["SCTID:237817008","NCIT:C120372","UMLS:C0342544","MEDGEN:575094","ICD9:259.1","Orphanet:169615"],"termid":"MONDO:0015713","xrefs":{"Monarch":{"xref_id":"0015713"}}}


id: PBO:0116812
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"EGFLAM antisense RNA 5","termid":"PBO:0116812"}


id: GO:0043523
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons.","definition_xrefs":["GOC:go_curators","GOC:mtg_apoptosis"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of apoptotic process","termid":"GO:0042981"},{"relation_name":"regulates","term_name":"neuron apoptotic process","termid":"GO:0051402"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of neuron apoptotic process","synonyms":[{"name":"regulation of apoptosis of neuronal cells","type":"exact"},{"name":"regulation of apoptosis of neurons","type":"exact"},{"name":"regulation of neuron apoptosis","type":"narrow"},{"name":"regulation of neuron programmed cell death","type":"exact"},{"name":"regulation of neuronal cell programmed cell death","type":"exact"},{"name":"regulation of programmed cell death of neuronal cells","type":"exact"},{"name":"regulation of programmed cell death, neurons","type":"exact"}],"termid":"GO:0043523"}


id: PBO:0042050
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coiled-coil domain containing 107","termid":"PBO:0042050"}


id: MONDO:0003673
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An electrocardiographic finding of an injury in leads corresponding to the anatomic region of the apex of the heart.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myocardial infarction","termid":"MONDO:0005068"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"apical myocardial infarction","secondary_identifiers":["DOID:5848","MEDGEN:770959","UMLS:C3642319"],"termid":"MONDO:0003673","xrefs":{"Monarch":{"xref_id":"0003673"}}}


id: GO:0061193
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sensory organ development","termid":"GO:0007423"},{"relation_name":"part_of","term_name":"tongue development","termid":"GO:0043586"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"taste bud development","termid":"GO:0061193"}


id: MONDO:0007845
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary neoplastic syndrome","termid":"MONDO:0015356"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Kaposi sarcoma, susceptibility to","secondary_identifiers":["MEDGEN:761233","OMIM:148000","UMLS:C3538945"],"synonyms":[{"name":"Kaposi sarcoma, susceptibility to","type":"exact"},{"name":"multicentric Castleman disease, susceptibility to","type":"related"},{"name":"multiple idiopathic pigmented hemangiosarcoma, susceptibility to","type":"related"},{"name":"susceptibility to Kaposi sarcoma","type":"related"}],"termid":"MONDO:0007845","xrefs":{"Monarch":{"xref_id":"0007845"}}}


id: GO:0051691
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages, as carried out by individual cells.","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete cellular oligosaccharide metabolic process (obsolete GO:0051691)","synonyms":[{"name":"cellular oligosaccharide metabolism","type":"exact"}],"termid":"GO:0051691"}


id: PBO:0088724
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial [2Fe-2S] cluster assembly protein, LYR family Isd11","termid":"PBO:0088724"}


id: GO:0018488
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: an aromatic aldehyde + O2 + H2O = an aromatic acid + hydrogen peroxide.","definition_xrefs":["EC:1.2.3.9"],"direct_ancestors":[{"relation_name":"is_a","term_name":"aldehyde oxidase activity","termid":"GO:0004031"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"aryl-aldehyde oxidase activity","secondary_identifiers":["RHEA:18569","UM-BBD_reactionID:r0145","MetaCyc:ARYL-ALDEHYDE-OXIDASE-RXN"],"synonyms":[{"name":"aryl-aldehyde:oxygen oxidoreductase activity","type":"related"}],"termid":"GO:0018488"}


id: PBO:0040716
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BAF chromatin remodeling complex subunit BCL7B","termid":"PBO:0040716"}


id: MONDO:0800114
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A polyclonal hyperplasia of bronchiolar associated lymphoid tissue characterized by the development of lymphoid follicles with germinal centers in walls of the small airways.","definition_xrefs":["PMID:32040879"],"direct_ancestors":[{"relation_name":"is_a","term_name":"idiopathic interstitial pneumonia","termid":"MONDO:0002429"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"follicular bronchiolits","termid":"MONDO:0800114","xrefs":{"Monarch":{"xref_id":"0800114"}}}


id: PBO:0045471
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"developmentally regulated GTP binding protein 1","termid":"PBO:0045471"}


id: MONDO:1011101
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any nephropathy characterized by extensive oxalate crystal deposition that occurs in sheep due to a mutation in the AGXT gene.","definition_xrefs":["PMID:33003365"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease, non-human animal","termid":"MONDO:1011321"},{"relation_name":"is_a","term_name":"nephropathy, sheep","termid":"MONDO:1012188"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"primary hyperoxaluria, AGXT-related, sheep","secondary_identifiers":["OMIA:001672-9940"],"synonyms":[{"name":"primary hyperoxaluria type I (Oxalosis I), sheep","type":"related"}],"termid":"MONDO:1011101","xrefs":{"Monarch":{"xref_id":"1011101"}}}


id: PBO:0068376
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ring finger protein 169","termid":"PBO:0068376"}


