# terms

id: MONDO:0013362
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"THOC6-related developmental delay-microcephaly-facial dysmorphism syndrome","secondary_identifiers":["MEDGEN:462289","OMIM:613680","UMLS:C3150939","GARD:17558","Orphanet:363444"],"synonyms":[{"name":"BBIS","type":"exact"},{"name":"BEAULIEU-BOYCOTT-Innes syndrome","type":"related"},{"name":"Beaulieu-Boycott-Innes syndrome","type":"exact"},{"name":"microcephaly, intellectual disability, and distinctive facies, with Cardiac and genitourinary malformations","type":"related"},{"name":"microcephaly, mental retardation, and distinctive facies, with Cardiac and genitourinary malformations","type":"related"}],"termid":"MONDO:0013362","xrefs":{"Monarch":{"xref_id":"0013362"}}}


id: PBO:0003122
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"1.11.1.-","termid":"PBO:0003122"}


id: PBO:0087445
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit II of cytochrome c oxidase (Complex IV); Complex IV is the terminal member of the mitochondrial inner membrane electron transport chain; one of three mitochondrially-encoded subunits","termid":"PBO:0087445"}


id: PBO:0042380
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CD244 molecule","termid":"PBO:0042380"}


id: PBO:0048840
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glycine N-methyltransferase","termid":"PBO:0048840"}


id: GO:0001921
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of receptor recycling.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of receptor recycling","termid":"GO:0001919"},{"relation_name":"is_a","term_name":"positive regulation of macromolecule metabolic process","termid":"GO:0010604"},{"relation_name":"is_a","term_name":"positive regulation of signaling","termid":"GO:0023056"},{"relation_name":"positively_regulates","term_name":"receptor recycling","termid":"GO:0001881"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"positive regulation of receptor recycling","synonyms":[{"name":"activation of receptor recycling","type":"narrow"},{"name":"stimulation of receptor recycling","type":"narrow"},{"name":"up regulation of receptor recycling","type":"exact"},{"name":"up-regulation of receptor recycling","type":"exact"},{"name":"upregulation of receptor recycling","type":"exact"}],"termid":"GO:0001921"}


id: GO:0010601
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.","definition_xrefs":["PMID:18287041"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of auxin biosynthetic process","termid":"GO:0010600"},{"relation_name":"is_a","term_name":"positive regulation of hormone biosynthetic process","termid":"GO:0046886"},{"relation_name":"is_a","term_name":"positive regulation of auxin metabolic process","termid":"GO:0090355"},{"relation_name":"positively_regulates","term_name":"auxin biosynthetic process","termid":"GO:0009851"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of auxin biosynthetic process","termid":"GO:0010601"}


id: MONDO:0012355
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An autosomal recessive disorder caused by mutations in the TRIOBP gene, encoding TRIO and F-actin-binding protein. The condition is characterized by severe to profound sensorineural hearing loss.","definition_xrefs":["NCIT:C129023"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hearing loss, autosomal recessive","termid":"MONDO:0019588"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0019497"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0019497"],"is_obsolete":false,"name":"autosomal recessive nonsyndromic hearing loss 28","secondary_identifiers":["OMIM:609823","UMLS:C1853276","DOID:0110486","GARD:22617","MEDGEN:342839","MESH:C565218"],"synonyms":[{"name":"DFNB28","type":"narrow"},{"name":"TRIOBP autosomal recessive nonsyndromic deafness","type":"narrow"},{"name":"autosomal recessive deafness 28","type":"narrow"},{"name":"autosomal recessive nonsyndromic deafness 28","type":"narrow"},{"name":"autosomal recessive nonsyndromic deafness caused by mutation in TRIOBP","type":"narrow"},{"name":"autosomal recessive nonsyndromic deafness type 28","type":"narrow"},{"name":"autosomal recessive nonsyndromic hearing loss 28","type":"exact"},{"name":"deafness, autosomal recessive 28","type":"narrow"},{"name":"deafness, autosomal recessive type 28","type":"narrow"}],"termid":"MONDO:0012355","xrefs":{"Monarch":{"xref_id":"0012355"}}}


id: PBO:0084584
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Merged open reading frame; does not encode a discrete protein; YCR055C was originally annotated as an independent ORF, but as a result of sequence changes, it was merged with two other ORFs into a single reading frame, designated YCR057C","termid":"PBO:0084584"}


id: PBO:0055267
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2694","termid":"PBO:0055267"}


id: GO:0034928
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 1-hydroxypyrene + O2 + 2 H+ + 2 e- = 1-hydroxypyrene-6,7-oxide + H2O.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete 1-hydroxypyrene 6,7-monooxygenase activity (obsolete GO:0034928)","termid":"GO:0034928"}


id: PR:Q09195
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A delta(14)-sterol reductase that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO04051"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"delta(14)-sterol reductase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC16G5.18","secondary_identifiers":["UniProtKB:Q09195"],"synonyms":[{"name":"C-14 sterol reductase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-TM7SF2","type":"exact"},{"name":"sterol C14-reductase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q09195"}


id: GO:1990721
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. A protein complex that is capable of dephosphorylation of alky, aryl and acyl orthophosphate monoesters and phosphorylated proteins. Optimal activity in acidic environment (pH 4-6). In mammals it consists of a homodimer of ACPP.","definition_xrefs":["PMID:12525165","GOC:bhm"],"gene_count":0,"genotype_count":0,"name":"obsolete prostatic acid phosphatase complex (obsolete GO:1990721)","synonyms":[{"name":"ACPP homodimer complex","type":"narrow"},{"name":"PAP complex","type":"exact"},{"name":"prostatic acid phosphatase complex","type":"exact"}],"termid":"GO:1990721"}


id: PBO:0054335
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1728","termid":"PBO:0054335"}


id: PBO:0014596
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complements S. cerevisiae CDC28 when introns removed","termid":"PBO:0014596"}


id: GO:0090448
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucosinolate(out) + H+(out) = glucosinolate(in) + H+(in).","definition_xrefs":["PMID:22864417"],"direct_ancestors":[{"relation_name":"is_a","term_name":"solute:proton symporter activity","termid":"GO:0015295"},{"relation_name":"is_a","term_name":"glucosinolate transmembrane transporter activity","termid":"GO:0141165"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0003674","GO:0005215","GO:0022857"],"is_obsolete":false,"name":"glucosinolate:proton symporter activity","synonyms":[{"name":"glucosinolate:hydrogen symporter activity","type":"exact"}],"termid":"GO:0090448"}


id: GO:0141106
data:
  {"annotated_genes":["SJAG_04890"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[77137],"is_not":false,"summary":null,"term":"GO:0141106"}]},"cv_name":"molecular_function","definition":"Binds to and increases the activity of a methyltransferase.","definition_xrefs":["GOC:curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"enzyme activator activity","termid":"GO:0008047"},{"relation_name":"is_a","term_name":"methyltransferase regulator activity","termid":"GO:0141107"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04890":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0030234"},{"rel_name":"is_a","termid":"GO:0098772"},{"rel_name":"is_a","termid":"GO:0140677"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0030234","GO:0098772","GO:0140677"],"is_obsolete":false,"name":"tRNA methyltransferase activator activity","references_by_uniquename":{"GO_REF:0000033":null},"termid":"GO:0141106","terms_by_termid":{"GO:0141106":null}}


id: GO:0061450
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ameboidal-type cell migration","termid":"GO:0001667"},{"relation_name":"part_of","term_name":"embryo implantation","termid":"GO:0007566"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"trophoblast cell migration","termid":"GO:0061450"}


id: GO:0097343
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The aggregation, arrangement and bonding together of a set of components to form a ripoptosome, a protein complex whose formation can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more.","definition_xrefs":["PMID:22274400","GOC:mtg_apoptosis"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex assembly","termid":"GO:0065003"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0065003"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0065003","GO:0008150","GO:0044085"],"is_obsolete":false,"name":"ripoptosome assembly","termid":"GO:0097343"}


id: PBO:0004043
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"60S ribosomal protein L35a (predicted)","termid":"PBO:0004043"}


id: PBO:0073832
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 7 member 8","termid":"PBO:0073832"}


id: PBO:0017495
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"polyketide cyclase SnoaL-like domain protein","termid":"PBO:0017495"}


id: PBO:0088300
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Alpha/Beta hydrolase fold","termid":"PBO:0088300"}


id: PBO:0027217
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_cytosolic_large:small_ribosomal_subunit_ratio","termid":"PBO:0027217"}


id: MONDO:1010664
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Autoimmune thrombocytopenic purpura that occurs in pig.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autoimmune thrombocytopenic purpura, non-human animal","termid":"MONDO:1010081"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"autoimmune thrombocytopenic purpura, pig","secondary_identifiers":["OMIA:001104-9823"],"termid":"MONDO:1010664","xrefs":{"Monarch":{"xref_id":"1010664"}}}


id: MONDO:0000806
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. A allergy involving a Turbo cornutus.","definition_xrefs":["MONDO:patterns/allergy"],"gene_count":0,"genotype_count":0,"name":"obsolete horned turban snail allergy (obsolete MONDO:0000806)","secondary_identifiers":["DOID:0060531"],"synonyms":[{"name":"Turbo cornutus allergic disease","type":"exact"},{"name":"Turbo cornutus allergy","type":"exact"},{"name":"Turbo cornutus caused allergic disease","type":"exact"},{"name":"allergy of Turbo cornutus","type":"exact"}],"termid":"MONDO:0000806","xrefs":{"Monarch":{"xref_id":"0000806"}}}


id: PBO:0018194
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vacuolar transmembrane transporter Hmt1","termid":"PBO:0018194"}


id: MONDO:0010805
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Bladder exstrophy (or classic bladder exstrophy; CEB) is a congenital genitourinary malformation belonging to the spectrum of the exstrophy-epispadias complex (EEC) and is characterized by an evaginated bladder plate, epispadias and an anterior defect of the pelvis, pelvic floor and abdominal wall.","definition_xrefs":["Orphanet:93930"],"direct_ancestors":[{"relation_name":"is_a","term_name":"exstrophy-epispadias complex","termid":"MONDO:0017919"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240"],"is_obsolete":false,"name":"bladder exstrophy","secondary_identifiers":["NCIT:C123207","GARD:6398","MEDGEN:2661","SCTID:61758007","icd11.foundation:1927556258","MESH:D001746","DOID:0080174","HP:0002836","NORD:860","UMLS:C0005689","ICD9:753.5"],"synonyms":[{"name":"Bladder Exstrophy-Epispadias-Cloacal Exstrophy Complex","type":"exact"},{"name":"bladder exstrophy","type":"exact"},{"name":"bladder exstrophy (disease)","type":"exact"},{"name":"bladder exstrophy and epispadias Complex","type":"related"},{"name":"classic exstrophy of the bladder","type":"exact"},{"name":"ectopia vesicae","type":"exact"},{"name":"exstrophy of bladder","type":"related"},{"name":"exstrophy of the bladder","type":"related"}],"termid":"MONDO:0010805","xrefs":{"Monarch":{"xref_id":"0010805"}}}


id: PBO:0077870
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TPM4 pseudogene 1","termid":"PBO:0077870"}


id: GO:1903721
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of I-kappaB phosphorylation.","definition_xrefs":["GOC:TermGenie","PMID:23675531","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of protein phosphorylation","termid":"GO:0001934"},{"relation_name":"is_a","term_name":"regulation of I-kappaB phosphorylation","termid":"GO:1903719"},{"relation_name":"positively_regulates","term_name":"I-kappaB phosphorylation","termid":"GO:0007252"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of I-kappaB phosphorylation","synonyms":[{"name":"activation of I-kappaB phosphorylation","type":"narrow"},{"name":"activation of IKB phosphorylation","type":"narrow"},{"name":"activation of IkappaB phosphorylation","type":"narrow"},{"name":"activation of inhibitor of NF-kappaB phosphorylation","type":"narrow"},{"name":"activation of inhibitor of kappaB phosphorylation","type":"narrow"},{"name":"positive regulation of IKB phosphorylation","type":"exact"},{"name":"positive regulation of IkappaB phosphorylation","type":"exact"},{"name":"positive regulation of inhibitor of NF-kappaB phosphorylation","type":"exact"},{"name":"positive regulation of inhibitor of kappaB phosphorylation","type":"exact"},{"name":"up regulation of I-kappaB phosphorylation","type":"exact"},{"name":"up regulation of IKB phosphorylation","type":"exact"},{"name":"up regulation of IkappaB phosphorylation","type":"exact"},{"name":"up regulation of inhibitor of NF-kappaB phosphorylation","type":"exact"},{"name":"up regulation of inhibitor of kappaB phosphorylation","type":"exact"},{"name":"up-regulation of I-kappaB phosphorylation","type":"exact"},{"name":"up-regulation of IKB phosphorylation","type":"exact"},{"name":"up-regulation of IkappaB phosphorylation","type":"exact"},{"name":"up-regulation of inhibitor of NF-kappaB phosphorylation","type":"exact"},{"name":"up-regulation of inhibitor of kappaB phosphorylation","type":"exact"},{"name":"upregulation of I-kappaB phosphorylation","type":"exact"},{"name":"upregulation of IKB phosphorylation","type":"exact"},{"name":"upregulation of IkappaB phosphorylation","type":"exact"},{"name":"upregulation of inhibitor of NF-kappaB phosphorylation","type":"exact"},{"name":"upregulation of inhibitor of kappaB phosphorylation","type":"exact"}],"termid":"GO:1903721"}


id: PBO:0077527
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein 241","termid":"PBO:0077527"}


id: GO:1905635
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The aggregation, arrangement and bonding together of a set of components to form a FACT complex.","definition_xrefs":["GOC:TermGenie","PMID:20889714","GO_REF:0000079"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex assembly","termid":"GO:0065003"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0065003"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0044085","GO:0065003"],"is_obsolete":false,"name":"FACT complex assembly","synonyms":[{"name":"FACT complex formation","type":"exact"},{"name":"Facilitates chromatin transcription complex assembly","type":"exact"},{"name":"Facilitates chromatin transcription complex formation","type":"exact"}],"termid":"GO:1905635"}


id: FYPO:0000972
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is greater than normal.","definition_xrefs":["PMID:22064477","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal cellular physical quality phenotype during vegetative growth","termid":"FYPO:0004639"},{"relation_name":"is_a","term_name":"increased number of Rad52 foci","termid":"FYPO:0004709"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"increased number of Rad52 foci during vegetative growth","synonyms":[{"name":"increased number of Rad22 foci during vegetative growth","type":"exact"},{"name":"increased number of Rad52 foci during mitotic cell cycle","type":"related"}],"termid":"FYPO:0000972"}


id: MONDO:0011150
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"progeroid syndrome","termid":"MONDO:0015333"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"premature aging syndrome","termid":"MONDO:0019303"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0019303"}],"interesting_parent_ids":["MONDO:0019303"],"is_obsolete":false,"name":"acroosteolysis-keloid-like lesions-premature aging syndrome","secondary_identifiers":["Orphanet:363665","MEDGEN:400936","GARD:4276","UMLS:C1866182","MESH:C536653","OMIM:601812"],"synonyms":[{"name":"PENTT","type":"related"},{"name":"Penttinen-aula syndrome","type":"related"},{"name":"premature ageing syndrome Penttinen type","type":"related"},{"name":"premature ageing syndrome, Penttinen type","type":"exact"},{"name":"premature aging syndrome Penttinen type","type":"related"},{"name":"premature aging syndrome, Penttinen type","type":"exact"},{"name":"prematurely aged appearance, delayed bone maturation, acro-osteolysis, and brachydactyly","type":"related"},{"name":"progeroid syndrome, Penttinen type","type":"related"}],"termid":"MONDO:0011150","xrefs":{"Monarch":{"xref_id":"0011150"}}}


id: MONDO:0032841
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Usher syndrome, type 1M","secondary_identifiers":["MEDGEN:1684669","GARD:16370","OMIM:618632","UMLS:C5231434"],"synonyms":[{"name":"USH1M","type":"related"},{"name":"USHER SYNDROME, TYPE 1M","type":"related"}],"termid":"MONDO:0032841","xrefs":{"Monarch":{"xref_id":"0032841"}}}


id: PBO:0050914
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"interferon induced protein with tetratricopeptide repeats 6, pseudogene","termid":"PBO:0050914"}


id: PBO:0088406
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peroxin-7","termid":"PBO:0088406"}


id: GO:1900187
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of cell adhesion involved in single-species biofilm formation.","definition_xrefs":["GOC:TermGenie","GOC:di"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cell-substrate adhesion","termid":"GO:0010810"},{"relation_name":"regulates","term_name":"cell adhesion involved in single-species biofilm formation","termid":"GO:0043709"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0007155"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0007155","GO:0008150"],"is_obsolete":false,"name":"regulation of cell adhesion involved in single-species biofilm formation","synonyms":[{"name":"regulation of cell adhesion during single-species biofilm formation","type":"related"}],"termid":"GO:1900187"}


id: MONDO:0013705
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive non-syndromic intellectual disability","termid":"MONDO:0019502"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0037792"},{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0037792","MONDO:0006025","MONDO:0005066"],"is_obsolete":false,"name":"intellectual disability, autosomal recessive 19","secondary_identifiers":["MEDGEN:482171","GARD:22558","UMLS:C3280541","OMIM:614343"],"synonyms":[{"name":"MRT19","type":"exact"},{"name":"intellectual disability, autosomal recessive 19","type":"exact"},{"name":"mental retardation, autosomal recessive 19","type":"related"}],"termid":"MONDO:0013705","xrefs":{"Monarch":{"xref_id":"0013705"}}}


id: GO:0004210
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete caspase-7 activity (obsolete GO:0004210)","synonyms":[{"name":"caspase-7 activity","type":"exact"}],"termid":"GO:0004210"}


id: FYPO:0007505
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at one or more specific promoter elements is decreased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein localization to chromatin during vegetative growth","termid":"FYPO:0000452"},{"relation_name":"is_a","term_name":"decreased protein localization to chromatin","termid":"FYPO:0006631"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000138","FYPO:0001985","FYPO:0000002","FYPO:0005447"],"is_obsolete":false,"name":"decreased protein localization to chromatin at promoter","synonyms":[{"name":"decreased protein localisation to chromatin at promoter","type":"exact"},{"name":"decreased protein localization to chromatin at promoter during mitotic cell cycle","type":"related"},{"name":"decreased protein localization to chromatin at promoter during vegetative growth","type":"exact"},{"name":"reduced protein localization to chromatin at promoter","type":"exact"}],"termid":"FYPO:0007505"}


id: GO:0060836
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels.","definition_xrefs":["GOC:dph","GOC:tb","GOC:sdb_2009"],"direct_ancestors":[{"relation_name":"is_a","term_name":"endothelial cell differentiation","termid":"GO:0045446"},{"relation_name":"part_of","term_name":"lymph vessel development","termid":"GO:0001945"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"lymphatic endothelial cell differentiation","termid":"GO:0060836"}


id: PBO:0057654
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 1246","termid":"PBO:0057654"}


id: PBO:0058944
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MIX23 pseudogene 3","termid":"PBO:0058944"}


id: FYPO:0001266
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to salt stress.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein phosphorylation during cellular response to osmotic stress","termid":"FYPO:0002290"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0001312","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"normal protein phosphorylation during cellular response to salt stress","synonyms":[{"name":"normal protein phosphorylation during cellular response to salt stress during mitotic cell cycle","type":"related"},{"name":"normal protein phosphorylation during cellular response to salt stress during vegetative growth","type":"exact"}],"termid":"FYPO:0001266"}


id: MONDO:0021456
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign neoplasm that involves the sternum.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"thoracic benign neoplasm","termid":"MONDO:0000634"},{"relation_name":"is_a","term_name":"musculoskeletal system benign neoplasm","termid":"MONDO:0000636"},{"relation_name":"is_a","term_name":"sternal neoplasm","termid":"MONDO:0021578"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"benign neoplasm of sternum","secondary_identifiers":["MEDGEN:87573","SCTID:92410006","NCIT:C8416","UMLS:C0347312"],"synonyms":[{"name":"benign neoplasm of the sternum","type":"exact"},{"name":"benign sternal neoplasm","type":"exact"},{"name":"benign sternal tumor","type":"exact"},{"name":"benign sternal tumour","type":"exact"},{"name":"benign tumor of sternum","type":"exact"},{"name":"benign tumor of the sternum","type":"exact"},{"name":"benign tumour of sternum","type":"exact"},{"name":"benign tumour of the sternum","type":"exact"},{"name":"sternum benign neoplasm","type":"exact"}],"termid":"MONDO:0021456","xrefs":{"Monarch":{"xref_id":"0021456"}}}


id: MONDO:0007627
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Focal facial dermal dysplasia type I (FFDD1), also known as Brauer syndrome, is a focal facial dysplasia (FFDD) characterized by congenital bitemporal cutis aplasia.","definition_xrefs":["Orphanet:79133"],"direct_ancestors":[{"relation_name":"is_a","term_name":"focal facial dermal dysplasia","termid":"MONDO:0018363"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"focal facial dermal dysplasia type I","secondary_identifiers":["MEDGEN:1718224","OMIM:136500","UMLS:C5235196","GARD:16524"],"synonyms":[{"name":"Brauer syndrome","type":"exact"},{"name":"FFDD type I","type":"exact"},{"name":"FFDD, type 1","type":"related"},{"name":"FFDD1","type":"exact"},{"name":"bitemporal aplasia cutis congenita","type":"exact"},{"name":"focal facial dermal dysplasia 1, Brauer type","type":"exact"},{"name":"focal facial dermal dysplasia type 1","type":"exact"},{"name":"hereditary symmetrical aplastic nevi of temples","type":"related"}],"termid":"MONDO:0007627","xrefs":{"Monarch":{"xref_id":"0007627"}}}


id: PBO:0050976
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"interferon related developmental regulator 2","termid":"PBO:0050976"}


id: MONDO:0030854
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Ehlers-Danlos/osteogenesis imperfecta syndrome","termid":"MONDO:0016470"},{"relation_name":"is_a","term_name":"COL1A1-related Ehlers-Danlos syndrome","termid":"MONDO:0100599"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"combined osteogenesis imperfecta and Ehlers-Danlos syndrome 1","secondary_identifiers":["MEDGEN:1763836","OMIM:619115","GARD:18316","UMLS:C5436842"],"synonyms":[{"name":"OIEDS Syndrome 1","type":"exact"},{"name":"OIEDS1","type":"exact"},{"name":"combined osteogenesis imperfecta and Ehlers-Danlos syndrome 1","type":"exact"}],"termid":"MONDO:0030854","xrefs":{"Monarch":{"xref_id":"0030854"}}}


id: MONDO:0011917
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any focal segmental glomerulosclerosis in which the cause of the disease is a mutation in the CD2AP gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inherited disease susceptibility","termid":"MONDO:0020573"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"focal segmental glomerulosclerosis 3, susceptibility to","secondary_identifiers":["OMIM:607832","DOID:0112245","MEDGEN:335850","UMLS:C1842982"],"synonyms":[{"name":"CD2AP focal segmental glomerulosclerosis","type":"exact"},{"name":"FSGS3","type":"related"},{"name":"focal segmental glomerulosclerosis 3, susceptibility to","type":"exact"},{"name":"focal segmental glomerulosclerosis caused by mutation in CD2AP","type":"exact"},{"name":"glomerulosclerosis, focal segmental, 3","type":"exact"},{"name":"glomerulosclerosis, focal segmental, 3, susceptibility to","type":"related"},{"name":"susceptibility to focal segmental glomerulosclerosis 3","type":"related"}],"termid":"MONDO:0011917","xrefs":{"Monarch":{"xref_id":"0011917"}}}


id: GO:0060941
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The commitment of an epicardial cell to a cardiac fibroblast cell fate and its capacity to differentiate into a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.","definition_xrefs":["GOC:mtg_heart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cardiac fibroblast cell fate commitment","termid":"GO:0060937"},{"relation_name":"part_of","term_name":"epicardium-derived cardiac fibroblast cell differentiation","termid":"GO:0060938"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"epicardium-derived cardiac fibroblast cell fate commitment","termid":"GO:0060941"}


id: GO:0003743
data:
  {"annotated_genes":["SJAG_03147","SJAG_00466","SJAG_03472","SJAG_01954","SJAG_02856","SJAG_01659","SJAG_02995","SJAG_04635","SJAG_02628","SJAG_03732","SJAG_03678","SJAG_04891","SJAG_03996","SJAG_04900","SJAG_05003","SJAG_00786","SJAG_04744","SJAG_02390","SJAG_04772","SJAG_01576","SJAG_03788","SJAG_00507","SJAG_00662","SJAG_02307","SJAG_01487","SJAG_02164","SJAG_03223","SJAG_03629","SJAG_02376","SJAG_03433","SJAG_02471","SJAG_01117","SJAG_01643","SJAG_04981"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[58443,60159,60938,61899,62996,64700,70259,73135,73340,73656,73761,73969,74214,74233,75661,75956,76160,76233,76544,76911,77375,78325,78935,79195,79367,79373,79759,80259,80821,82025,89334,107415,107440,117482],"is_not":false,"summary":null,"term":"GO:0003743"}]},"cv_name":"molecular_function","definition":"Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"translation factor activity","termid":"GO:0180051"}],"gene_count":34,"genes_by_uniquename":{"SJAG_00466":null,"SJAG_00507":null,"SJAG_00662":null,"SJAG_00786":null,"SJAG_01117":null,"SJAG_01487":null,"SJAG_01576":null,"SJAG_01643":null,"SJAG_01659":null,"SJAG_01954":null,"SJAG_02164":null,"SJAG_02307":null,"SJAG_02376":null,"SJAG_02390":null,"SJAG_02471":null,"SJAG_02628":null,"SJAG_02856":null,"SJAG_02995":null,"SJAG_03147":null,"SJAG_03223":null,"SJAG_03433":null,"SJAG_03472":null,"SJAG_03629":null,"SJAG_03678":null,"SJAG_03732":null,"SJAG_03788":null,"SJAG_03996":null,"SJAG_04635":null,"SJAG_04744":null,"SJAG_04772":null,"SJAG_04891":null,"SJAG_04900":null,"SJAG_04981":null,"SJAG_05003":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674"],"is_obsolete":false,"name":"translation initiation factor activity","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-72621","Reactome:R-HSA-72697","Reactome:R-HSA-72722","GO:0003745","GO:0003744"],"termid":"GO:0003743","terms_by_termid":{"GO:0003743":null}}


id: FYPO:0006585
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the localization of a protein to the plasma membrane at the tip of a shmoo, or mating projection, is abolished, and the protein is present in the endoplasmic reticulum instead.","definition_xrefs":["PMID:29134248","PomBase:mah"],"direct_ancestors":[{"relation_name":"has_part","term_name":"protein mislocalized to endoplasmic reticulum","termid":"FYPO:0006590"},{"relation_name":"is_a","term_name":"abolished protein localization to shmoo tip","termid":"FYPO:0006505"},{"relation_name":"is_a","term_name":"abnormal protein localization to shmoo tip membrane","termid":"FYPO:0006584"},{"relation_name":"is_a","term_name":"protein mislocalized to endoplasmic reticulum","termid":"FYPO:0006590"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000138"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0005447","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"abolished protein localization to shmoo tip membrane, with protein mislocalized to endoplasmic reticulum","synonyms":[{"name":"abnormal protein localization to plasma membrane at shmoo tip, with protein mislocalized to endoplasmic reticulum","type":"exact"},{"name":"abnormal protein localization to shmoo membrane fusion domain, with protein mislocalized to endoplasmic reticulum","type":"exact"},{"name":"abnormal protein localization to shmoo projection membrane, with protein mislocalized to endoplasmic reticulum","type":"related"},{"name":"abolished protein localisation to mating projection tip membrane, with protein mislocalised to endoplasmic reticulum","type":"exact"},{"name":"abolished protein localization to mating projection tip membrane, with protein mislocalized to endoplasmic reticulum","type":"exact"},{"name":"abolished protein localization to shmoo tip membrane, with protein mislocalized to ER","type":"exact"},{"name":"protein localization to shmoo tip membrane abolished, with protein mislocalized to endoplasmic reticulum","type":"related"}],"termid":"FYPO:0006585"}


id: PR:O94614
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- chr4 gene.","definition_xrefs":["UniProtKB:O94614","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chitin synthase regulatory factor 4 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC1289.01c","synonyms":[{"name":"Chs four homolog 3 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-chr4","type":"exact"}],"termid":"PR:O94614"}


id: MONDO:0020572
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Complex regional pain syndrome type 2 (CRPS2), or causalgia is a form of complex regional pain syndrome that develops after damage to a peripheral nerve and is characterized by spontaneous pain, allodynia and hyperalgesia, not necessarily limited to the territory of the injured nerve, as well as at some point, edema, changes in skin blood flow or sudomotor dysfunction in the pain area.","definition_xrefs":["Orphanet:99994"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"complex regional pain syndrome","termid":"MONDO:0019369"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"complex regional pain syndrome type 2","secondary_identifiers":["MedDRA:10064335","MEDGEN:2918","MESH:D002422","NCIT:C121572","SCTID:408751001","UMLS:C0007462","DOID:3222","GARD:19727","EFO:1000854","MedDRA:10007825"],"synonyms":[{"name":"CRPS II","type":"exact"},{"name":"Complex regional pain syndrome II","type":"exact"},{"name":"Complex regional pain syndrome, type II","type":"exact"},{"name":"causalgia","type":"exact"}],"termid":"MONDO:0020572","xrefs":{"Monarch":{"xref_id":"0020572"}}}


id: GO:0120211
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Fusion of the membrane of proacrosomal vesicle with the membrane of another proacrosomal vesicle to form the acrosome.","definition_xrefs":["GOC:krc","PMID:29991750"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vesicle fusion","termid":"GO:0006906"},{"relation_name":"part_of","term_name":"acrosome assembly","termid":"GO:0001675"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0061024"},{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0016192"},{"rel_name":"part_of","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0061024","GO:0044085","GO:0016192","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"proacrosomal vesicle fusion","termid":"GO:0120211"}


id: GO:0102572
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: N5-phenyl-L-glutamine + H2O = L-glutamate + aniline + H+.","definition_xrefs":["GOC:pz"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides","termid":"GO:0016811"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0016810"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016810","GO:0016787"],"is_obsolete":false,"name":"N-glutamylanilide hydrolase activity","secondary_identifiers":["RHEA:50684","MetaCyc:RXN-15251"],"termid":"GO:0102572"}


id: GO:1902528
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of protein linear polyubiquitination.","definition_xrefs":["GOC:TermGenie","PMID:21931591"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of protein polyubiquitination","termid":"GO:1902914"},{"relation_name":"regulates","term_name":"protein linear polyubiquitination","termid":"GO:0097039"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0070647"}],"interesting_parent_ids":["GO:0008150","GO:0070647"],"is_obsolete":false,"name":"regulation of protein linear polyubiquitination","synonyms":[{"name":"regulation of M1 linkage","type":"narrow"}],"termid":"GO:1902528"}


id: PBO:0071029
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L21 pseudogene 31","termid":"PBO:0071029"}


id: MONDO:0010645
data:
  {"annotated_genes":["SJAG_03375"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[89039],"is_not":false,"summary":null,"term":"MONDO:0010645"}]},"cv_name":"mondo","definition":"Oculocerebrorenal syndrome of Lowe (OCRL) is a multisystem disorder characterized by congenital cataracts, glaucoma, intellectual disabilities, postnatal growth retardation and renal tubular dysfunction with chronic renal failure.","definition_xrefs":["Orphanet:534"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"eye disorder","termid":"MONDO:0005328"},{"relation_name":"is_a","term_name":"inherited renal tubular disease","termid":"MONDO:0015962"},{"relation_name":"is_a","term_name":"inborn disorder of amino acid transport","termid":"MONDO:0019216"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03375":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"},{"rel_name":"is_a","termid":"MONDO:0004736"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240","MONDO:0004736","MONDO:0005328","MONDO:0005066"],"is_obsolete":false,"name":"oculocerebrorenal syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:309000","NCIT:C84940","UMLS:C0028860","DOID:1056","GARD:3295","MedDRA:10051707","icd11.foundation:1392767390","ICD9:270.8","MEDGEN:18145","NANDO:2100028","NANDO:2200188","NORD:1379","SCTID:79385002","MESH:D009800"],"synonyms":[{"name":"Lowe disease","type":"exact"},{"name":"Lowe oculo-cerebro-renal syndrome","type":"exact"},{"name":"Lowe oculocerebrorenal syndrome","type":"exact"},{"name":"Lowe syndrome","type":"exact"},{"name":"Lowe syndrome, X-linked recessive","type":"exact"},{"name":"OCR","type":"exact"},{"name":"OCRL","type":"exact"},{"name":"Ocrl1","type":"related"},{"name":"oculo-cerebro-renal dystrophy","type":"exact"},{"name":"oculo-cerebro-renal syndrome","type":"exact"},{"name":"oculocerebrorenal dystrophy","type":"exact"},{"name":"oculocerebrorenal syndrome","type":"exact"},{"name":"oculocerebrorenal syndrome of Lowe","type":"exact"},{"name":"phosphatidylinositol 4,5-biphosphate 5-phosphatase deficiency","type":"exact"},{"name":"phosphatidylinositol 4,5-bisphosphate 5-phosphatase deficiency","type":"related"}],"termid":"MONDO:0010645","terms_by_termid":{"MONDO:0010645":null},"xrefs":{"Monarch":{"xref_id":"0010645"}}}


id: FYPO:0002519
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which a cell cycle arrest that normally occurs in response to mitotic G2/M transition cell cycle checkpoint signaling does not occur. Abolished arrest may result from a problem with detection of conditions that normally trigger a checkpoint, transduction of the checkpoint signal, or the response to the checkpoint signal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"has_output","term_name":"premature mitotic G2/M phase transition","termid":"FYPO:0002516"},{"relation_name":"is_a","term_name":"abolished response to mitotic cell cycle checkpoint signaling","termid":"FYPO:0002518"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000298"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000631","FYPO:0000298","FYPO:0005447","FYPO:0001985","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"abolished response to mitotic G2/M transition checkpoint signaling","synonyms":[{"name":"abolished mitotic G2/M transition arrest","type":"related"},{"name":"cell cycle arrest resulting from mitotic G2/M transition checkpoint activation abolished","type":"exact"},{"name":"mitotic G2/M checkpoint arrest deficient","type":"related"}],"termid":"FYPO:0002519"}


id: PR:O13913
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC23C11.07 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O13913"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C23C11.07 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC23C11.07","synonyms":[{"name":"Spom972h-SPAC23C11.07","type":"exact"}],"termid":"PR:O13913"}


id: GO:1901759
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving beta-L-Ara4N-lipid A.","definition_xrefs":["GOC:yaf","PMID:19166326","GOC:TermGenie","PMID:17928292"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phospholipid metabolic process","termid":"GO:0006644"},{"relation_name":"is_a","term_name":"glycolipid metabolic process","termid":"GO:0006664"},{"relation_name":"is_a","term_name":"lipooligosaccharide metabolic process","termid":"GO:1901269"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006629","GO:0008150"],"is_obsolete":false,"name":"beta-L-Ara4N-lipid A metabolic process","synonyms":[{"name":"4-amino-4-deoxy-beta-L-arabinose-lipid A metabolic process","type":"exact"},{"name":"4-amino-4-deoxy-beta-L-arabinose-lipid A metabolism","type":"exact"},{"name":"beta-L-Ara4N-lipid A metabolism","type":"exact"}],"termid":"GO:1901759"}


id: GO:0015792
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which arabitol is transported across a lipid bilayer, from one side of a membrane to the other. Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polyol transmembrane transport","termid":"GO:0015791"},{"relation_name":"is_a","term_name":"carbohydrate transmembrane transport","termid":"GO:0034219"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0051179","GO:0006810","GO:0055085"],"is_obsolete":false,"name":"arabinitol transmembrane transport","synonyms":[{"name":"arabinitol transport","type":"related"},{"name":"arabitol transport","type":"related"}],"termid":"GO:0015792"}


id: PBO:0066310
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RBPJ pseudogene 4","termid":"PBO:0066310"}


id: PBO:0055454
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2886","termid":"PBO:0055454"}


id: PBO:0067511
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 652, pseudogene","termid":"PBO:0067511"}


id: MONDO:0015944
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Axial mesodermal dysplasia spectrum is a rare developmental defect during embryogenesis syndrome characterized by congenital manifestations of both oculo-auriculo-vertebral spectrum and caudal regression sequence. Phenotype is highly variable but patients typically present facial dysmorphism (incl. asymmetry, hypertelorism), auricular abnormalities (e.g. preauricular tags, microtia, absence of middle ear ossicles), skeletal malformations (hemivertebrae, hip dislocation, sacral agenesis/dysplasia, talipes equinovarus, flexion deformity of lower limbs), cardiac defects (dextrocardia, septal defects), renal and genitourinary anomalies (such as renal agensis/dysplasia, abnormal external genitalia, cryptorchidia), as well as anal anomalies such as anal atresia and rectovesical fistula.","definition_xrefs":["Orphanet:1834"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"disorder of development or morphogenesis","termid":"MONDO:0021147"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"axial mesodermal dysplasia spectrum","secondary_identifiers":["SCTID:765755006","MEDGEN:419853","MESH:C537790","UMLS:C2931613","GARD:213"],"synonyms":[{"name":"Russell Weaver Bull syndrome","type":"related"},{"name":"Russell-Weaver-Bull syndrome","type":"exact"},{"name":"blastogenesis defect","type":"exact"}],"termid":"MONDO:0015944","xrefs":{"Monarch":{"xref_id":"0015944"}}}


id: GO:0060263
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.","definition_xrefs":["GOC:tb","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of metabolic process","termid":"GO:0019222"},{"relation_name":"regulates","term_name":"respiratory burst","termid":"GO:0045730"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of respiratory burst","termid":"GO:0060263"}


id: FYPO:0005253
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of tamoxifen than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased resistance to chemical during vegetative growth","termid":"FYPO:0000126"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0002682"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0002682","FYPO:0005447","FYPO:0000003","FYPO:0001985","FYPO:0000139"],"is_obsolete":false,"name":"resistance to tamoxifen","synonyms":[{"name":"resistance to tamoxifen during mitotic cell cycle","type":"related"},{"name":"resistance to tamoxifen during vegetative growth","type":"exact"},{"name":"resistant to tamoxifen","type":"exact"}],"termid":"FYPO:0005253"}


id: PBO:0079216
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"thiosulfate sulfurtransferase like domain containing 1","termid":"PBO:0079216"}


id: PBO:0073417
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SET like protein","termid":"PBO:0073417"}


id: FYPO:0008376
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex of one or both cell tips does not occur during a cellular response to osmotic stress.","definition_xrefs":["PomBase:pc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished protein localization to cell cortex of cell tip during vegetative growth","termid":"FYPO:0006502"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320","FYPO:0001985","FYPO:0005447","FYPO:0000138"],"is_obsolete":false,"name":"abolished protein localization to cell cortex of cell tip during cellular response to osmotic stress","termid":"FYPO:0008376"}


id: PBO:0075613
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"secreted phosphoprotein 1","termid":"PBO:0075613"}


id: MONDO:0005524
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A carcinoma arising from the sweat glands. Representative examples include tubular carcinoma, spiradenocarcinoma, eccrine carcinoma, hidradenocarcinoma, and apocrine carcinoma.","definition_xrefs":["EFO:0005591"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sweat gland cancer","termid":"MONDO:0002206"},{"relation_name":"is_a","term_name":"adenocarcinoma","termid":"MONDO:0004970"},{"relation_name":"is_a","term_name":"skin appendage carcinoma","termid":"MONDO:0006973"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0005093"],"is_obsolete":false,"name":"sweat gland carcinoma","secondary_identifiers":["UMLS:C1412016","DOID:5667","MEDGEN:234685","ONCOTREE:AECA","ICDO:8400/3","NCIT:C6938"],"synonyms":[{"name":"carcinoma of sweat gland","type":"exact"},{"name":"carcinoma of the sweat gland","type":"exact"},{"name":"carcinoma, sweat gland, malignant","type":"exact"},{"name":"sweat gland carcinoma","type":"exact"},{"name":"sweat gland carcinoma/apocrine eccrine carcinoma","type":"related"}],"termid":"MONDO:0005524","xrefs":{"Monarch":{"xref_id":"0005524"}}}


id: PR:Q9P6M8
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- crp79 gene.","definition_xrefs":["UniProtKB:Q9P6M8","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mRNA export factor crp79 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1610.03c","synonyms":[{"name":"PABP (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-crp79","type":"exact"},{"name":"meiotic expression up-regulated protein 5 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"poly(A)-binding protein (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"polyadenylate-binding protein crp79 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9P6M8"}


id: GO:0030748
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: S-adenosyl-L-methionine + an amine = S-adenosyl-L-homocysteine + a methylated amine. Acts on primary, secondary and tertiary amines.","definition_xrefs":["EC:2.1.1.49"],"direct_ancestors":[{"relation_name":"is_a","term_name":"S-adenosylmethionine-dependent methyltransferase activity","termid":"GO:0008757"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016741"}],"interesting_parent_ids":["GO:0003824","GO:0016741","GO:0003674","GO:0016740"],"is_obsolete":false,"name":"amine N-methyltransferase activity","secondary_identifiers":["MetaCyc:AMINE-N-METHYLTRANSFERASE-RXN"],"synonyms":[{"name":"S-adenosyl-L-methionine:amine N-methyltransferase activity","type":"related"},{"name":"arylamine N-methyltransferase activity","type":"narrow"},{"name":"nicotine N-methyltransferase activity","type":"narrow"},{"name":"tryptamine N-methyltransferase activity","type":"narrow"},{"name":"tryptamine methyltransferase","type":"narrow"}],"termid":"GO:0030748"}


id: MONDO:0008540
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"congenital limb malformation","termid":"MONDO:0019054"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"extensor tendons of finger anomalies","secondary_identifiers":["OMIM:187390","MEDGEN:348302","Orphanet:3294","UMLS:C1861237","GARD:2597","MESH:C566068"],"synonyms":[{"name":"Hapnes Boman Skeie syndrome","type":"related"},{"name":"Hapnes-Boman-Skeie syndrome","type":"exact"},{"name":"anomalous insertion of extensor tendons of fingers","type":"related"},{"name":"tendons, extensor, of fingers, anomalous insertion OF","type":"related"}],"termid":"MONDO:0008540","xrefs":{"Monarch":{"xref_id":"0008540"}}}


id: GO:0033982
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 3-dehydro-L-gulonate 6-phosphate + H+ = L-xylulose 5-phosphate + CO2.","definition_xrefs":["RHEA:14353","EC:4.1.1.85"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxy-lyase activity","termid":"GO:0016831"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016829"],"is_obsolete":false,"name":"3-dehydro-L-gulonate-6-phosphate decarboxylase activity","secondary_identifiers":["KEGG_REACTION:R07125","MetaCyc:RXN0-705"],"synonyms":[{"name":"3-dehydro-L-gulonate-6-phosphate carboxy-lyase (L-xylulose-5-phosphate-forming) activity","type":"related"},{"name":"3-dehydro-L-gulonate-6-phosphate carboxy-lyase activity","type":"related"},{"name":"3-keto-L-gulonate 6-phosphate decarboxylase activity","type":"related"},{"name":"KGPDC","type":"related"},{"name":"SgaH","type":"related"},{"name":"SgbH","type":"related"},{"name":"UlaD","type":"related"}],"termid":"GO:0033982"}


id: MONDO:0004174
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An endometrioid adenocarcinoma arising from the endometrium. Morphologically it is characterized by the presence of malignant glandular cells containing glycogen vacuoles which are usually subnuclear and reminiscent of early secretory endometrium.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"endometrium adenocarcinoma","termid":"MONDO:0005461"},{"relation_name":"is_a","term_name":"endometrial endometrioid adenocarcinoma","termid":"MONDO:0006192"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"secretory uterine corpus endometrioid adenocarcinoma","secondary_identifiers":["ICDO:8382/3","UMLS:C1266057","MEDGEN:690079","DOID:7289","NCIT:C27839"],"synonyms":[{"name":"endometrial endometrioid adenocarcinoma, secretory variant","type":"exact"},{"name":"secretory uterine corpus endometrioid adenocarcinoma","type":"exact"}],"termid":"MONDO:0004174","xrefs":{"Monarch":{"xref_id":"0004174"}}}


id: PBO:0063626
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"profilin 1 pseudogene 2","termid":"PBO:0063626"}


id: PBO:0051938
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"intelectin 2","termid":"PBO:0051938"}


id: PBO:0031693
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_nucleus_localization","termid":"PBO:0031693"}


id: PBO:0086716
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative protein of unknown function; non-essential gene","termid":"PBO:0086716"}


id: PR:Q92355
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- sen1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q92355"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"helicase sen1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC6G9.10c","synonyms":[{"name":"Spom972h-sen1","type":"exact"}],"termid":"PR:Q92355"}


id: GO:1902852
data:
  {"annotated_genes":["SJAG_04597"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[96226],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1902854"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of nuclear migration during mitotic telophase.","definition_xrefs":["GO_REF:0000058","GOC:TermGenie","PMID:23087209"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of nuclear migration along microtubule","termid":"GO:1902838"},{"relation_name":"regulates","term_name":"nuclear migration during mitotic telophase","termid":"GO:0090561"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04597":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0008150"],"is_obsolete":false,"name":"regulation of nuclear migration during mitotic telophase","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:1902852","terms_by_termid":{"GO:1902854":null}}


id: PBO:0027178
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-actin_cortical_patches_present_in_increased_numbers_at_cell_tip_during_early_mitosis","termid":"PBO:0027178"}


id: PBO:0075627
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"shadow of prion protein","termid":"PBO:0075627"}


id: PBO:0043921
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ciliary rootlet coiled-coil, rootletin family member 2","termid":"PBO:0043921"}


id: PBO:0044349
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CYCS pseudogene 34","termid":"PBO:0044349"}


id: GO:0106363
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-cysteinyl-[protein] + S-adenosyl-L-methionine = H+ + S-adenosyl-L-homocysteine + S-methyl-L-cysteinyl-[protein].","definition_xrefs":["RHEA:66544","PMID:22158122","PMID:24235145","PMID:21481189","GOC:sp","PMID:25412445"],"direct_ancestors":[{"relation_name":"is_a","term_name":"S-methyltransferase activity","termid":"GO:0008172"},{"relation_name":"is_a","term_name":"protein methyltransferase activity","termid":"GO:0008276"},{"relation_name":"is_a","term_name":"S-adenosylmethionine-dependent methyltransferase activity","termid":"GO:0008757"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008276"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0008276","GO:0003824","GO:0140096","GO:0016741","GO:0016740","GO:0003674"],"is_obsolete":false,"name":"protein-cysteine methyltransferase activity","synonyms":[{"name":"protein cysteine methylase activity","type":"exact"},{"name":"protein cysteine methyltransferase activity","type":"exact"}],"termid":"GO:0106363"}


id: PBO:0089224
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA-binding transcription factor, Atf-CREB family Atf21","termid":"PBO:0089224"}


id: GO:0048021
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that alters the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin.","definition_xrefs":["GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of secondary metabolite biosynthetic process","termid":"GO:1900376"},{"relation_name":"regulates","term_name":"melanin biosynthetic process","termid":"GO:0042438"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0019748"}],"interesting_parent_ids":["GO:0019748","GO:0008150"],"is_obsolete":false,"name":"regulation of melanin biosynthetic process","synonyms":[{"name":"regulation of melanin anabolism","type":"exact"},{"name":"regulation of melanin biosynthesis","type":"exact"},{"name":"regulation of melanin formation","type":"exact"},{"name":"regulation of melanin synthesis","type":"exact"}],"termid":"GO:0048021"}


id: MONDO:0045008
data:
  {"annotated_genes":["SJAG_03024","SJAG_00717","SJAG_03509"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88409,88408],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011816"},{"annotations":[89033],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010035"}]},"cv_name":"mondo","definition":"A disease that has its basis in the disruption of cholesterol metabolic process.","definition_xrefs":["MONDO:design_pattern"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sterol metabolism disorder","termid":"MONDO:0019256"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00717":null,"SJAG_03024":null,"SJAG_03509":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0002525"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0002525"],"is_obsolete":false,"name":"cholesterol metabolism disease","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:575263","UMLS:C0342877","SCTID:123963007"],"synonyms":[{"name":"cholesterol metabolic process disease","type":"exact"},{"name":"cholesterol metabolism disease","type":"exact"},{"name":"disorder of cholesterol metabolic process","type":"exact"},{"name":"disorder of cholesterol metabolism","type":"exact"}],"termid":"MONDO:0045008","terms_by_termid":{"MONDO:0010035":null,"MONDO:0011816":null},"xrefs":{"Monarch":{"xref_id":"0045008"}}}


id: PBO:0052265
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lysine demethylase 3B","termid":"PBO:0052265"}


id: PBO:0072244
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S20 pseudogene 19","termid":"PBO:0072244"}


id: GO:0072014
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the proximal tubule over time, from its formation to the mature structure. In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nephron tubule development","termid":"GO:0072080"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"proximal tubule development","termid":"GO:0072014"}


id: PBO:0058471
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 5579","termid":"PBO:0058471"}


id: GO:0043097
data:
  {"annotated_genes":["SJAG_05029","SJAG_04264"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[99550,115674],"is_not":false,"summary":null,"term":"GO:0043097"}]},"cv_name":"biological_process","definition":"Any process that generates a pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose, from derivatives of it, without de novo synthesis.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pyrimidine-containing compound salvage","termid":"GO:0008655"},{"relation_name":"is_a","term_name":"nucleoside salvage","termid":"GO:0043174"},{"relation_name":"is_a","term_name":"pyrimidine nucleoside biosynthetic process","termid":"GO:0046134"}],"gene_count":2,"genes_by_uniquename":{"SJAG_04264":null,"SJAG_05029":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0055086","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"pyrimidine nucleoside salvage","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-73614"],"termid":"GO:0043097","terms_by_termid":{"GO:0043097":null}}


id: PBO:0079576
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin D pseudogene 1","termid":"PBO:0079576"}


id: PBO:0043135
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"capicua transcriptional repressor pseudogene 3","termid":"PBO:0043135"}


id: GO:0097725
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The modification of histone H3 by addition of two methyl groups to lysine at position 79 of the histone.","definition_xrefs":["GOC:hbye","PMID:27541139"],"gene_count":0,"genotype_count":0,"name":"obsolete histone H3-K79 dimethylation (obsolete GO:0097725)","synonyms":[{"name":"histone H3 K79 dimethylation","type":"exact"},{"name":"histone lysine H3 K79 dimethylation","type":"exact"}],"termid":"GO:0097725"}


id: GO:0052751
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: GDP-mannose + H2O = GMP + mannose-1-phosphate.","definition_xrefs":["PMID:16766526"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pyrophosphatase activity","termid":"GO:0016462"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016787","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"GDP-mannose hydrolase activity","synonyms":[{"name":"GDP-mannose pyrophosphatase activity","type":"related"}],"termid":"GO:0052751"}


id: MONDO:0010973
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any autosomal dominant nonsyndromic deafness in which the cause of the disease is a mutation in the GSDME gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant nonsyndromic hearing loss","termid":"MONDO:0019587"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0019497"}],"interesting_parent_ids":["MONDO:0000426","MONDO:0019497"],"is_obsolete":false,"name":"autosomal dominant nonsyndromic hearing loss 5","secondary_identifiers":["MESH:C563410","MEDGEN:331398","OMIM:600994","UMLS:C1832932","GARD:18102","DOID:0110575"],"synonyms":[{"name":"DFNA5","type":"narrow"},{"name":"GSDME autosomal dominant nonsyndromic deafness","type":"narrow"},{"name":"autosomal dominant deafness 5","type":"narrow"},{"name":"autosomal dominant nonsyndromic deafness 5","type":"narrow"},{"name":"autosomal dominant nonsyndromic deafness caused by mutation in GSDME","type":"narrow"},{"name":"autosomal dominant nonsyndromic deafness type 5","type":"narrow"},{"name":"deafness, autosomal dominant 5","type":"narrow"},{"name":"deafness, autosomal dominant type 5","type":"narrow"}],"termid":"MONDO:0010973","xrefs":{"Monarch":{"xref_id":"0010973"}}}


id: MONDO:1010553
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Patent urachus that occurs in white rhinoceros.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"patent urachus, non-human animal","termid":"MONDO:1010046"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"patent urachus, white rhinoceros","secondary_identifiers":["OMIA:000781-9807"],"termid":"MONDO:1010553","xrefs":{"Monarch":{"xref_id":"1010553"}}}


id: GO:0032265
data:
  {"annotated_genes":["SJAG_06634","SJAG_01298"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[77383,110112],"is_not":false,"summary":null,"term":"GO:0032265"}]},"cv_name":"biological_process","definition":"Any process which produces xanthosine monophosphate from derivatives of it, without de novo synthesis.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"XMP biosynthetic process","termid":"GO:0097293"},{"relation_name":"is_a","term_name":"purine ribonucleotide salvage","termid":"GO:0106380"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01298":null,"SJAG_06634":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0055086","GO:0044281"],"is_obsolete":false,"name":"XMP salvage","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0032265","terms_by_termid":{"GO:0032265":null}}


id: PBO:0003288
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosome biogenesis protein Rrp14-C (predicted)","termid":"PBO:0003288"}


id: MONDO:0011458
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any Leber congenital amaurosis in which the cause of the disease is a mutation in the AIPL1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cone-rod dystrophy","termid":"MONDO:0015993"},{"relation_name":"is_a","term_name":"Leber congenital amaurosis","termid":"MONDO:0018998"},{"relation_name":"is_a","term_name":"AIPL1-related retinopathy","termid":"MONDO:0100438"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"},{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0005328","MONDO:0002320"],"is_obsolete":false,"name":"Leber congenital amaurosis 4","secondary_identifiers":["ICD10CM:H35.5","MEDGEN:346808","MESH:C565778","OMIM:604393","UMLS:C1858386","DOID:0110332","GARD:9662"],"synonyms":[{"name":"AIPL1 Leber congenital amaurosis","type":"exact"},{"name":"LCA4","type":"exact"},{"name":"Leber congenital amaurosis 4","type":"exact"},{"name":"Leber congenital amaurosis caused by mutation in AIPL1","type":"exact"},{"name":"Leber congenital amaurosis type 4","type":"exact"},{"name":"amaurosis congenita of Leber, type 4","type":"related"},{"name":"cone-rod dystrophy","type":"broad"},{"name":"cone-rod dystrophy, Aipl1-related","type":"related"},{"name":"retinitis pigmentosa, juvenile","type":"related"},{"name":"retinitis pigmentosa, juvenile, Aipl1-related","type":"related"}],"termid":"MONDO:0011458","xrefs":{"Monarch":{"xref_id":"0011458"}}}


id: GO:0060652
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which anatomical structures of the mammary gland cord are generated and organized. Mammary gland cords form when the mammary gland bud invades the mammary fat.","definition_xrefs":["PMID:12558599","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epithelial tube morphogenesis","termid":"GO:0060562"},{"relation_name":"part_of","term_name":"mammary gland duct morphogenesis","termid":"GO:0060603"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mammary gland cord morphogenesis","synonyms":[{"name":"mammary gland sprout morphogenesis","type":"exact"}],"termid":"GO:0060652"}


id: PBO:0088136
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Vacuolar membrane zinc transporter; transports zinc from cytosol to vacuole for storage; also has role in resistance to zinc shock resulting from sudden influx of zinc into cytoplasm; human ortholog SLC30A10 functions as a Mn transporter and mutations in SLC30A10 cause neurotoxic accumulation of Mn in liver and brain; ZRC1 has a paralog, COT1, that arose from the whole genome duplication","termid":"PBO:0088136"}


id: PBO:0048216
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"gamma-aminobutyric acid type A receptor subunit rho3","termid":"PBO:0048216"}


id: PBO:0073032
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"scratch family transcriptional repressor 2","termid":"PBO:0073032"}


id: PBO:0110287
data:
  {"annotation_feature_type":"gene","cv_name":"species_dist","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"conserved in metozoa","termid":"PBO:0110287"}


id: PBO:0079015
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-SeC (TCA) 3-1","termid":"PBO:0079015"}


id: GO:0043661
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A membrane that surrounds one or more bacteroids (such as nitrogen-fixing bacteroids within legume root nodule cells).","definition_xrefs":["GOC:cc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"endocytic vesicle membrane","termid":"GO:0030666"},{"relation_name":"part_of","term_name":"bacteroid-containing symbiosome","termid":"GO:0043660"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0031410"}],"interesting_parent_ids":["GO:0031410","GO:0005575","GO:0005737"],"is_obsolete":false,"name":"peribacteroid membrane","termid":"GO:0043661"}


id: PBO:0065020
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peroxiredoxin 2 pseudogene 4","termid":"PBO:0065020"}


id: GO:1990165
data:
  {"annotated_genes":["SJAG_04410","SJAG_16460"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[78783,97697],"is_not":false,"summary":null,"term":"GO:1990165"}]},"cv_name":"molecular_function","definition":"Binding to damaged DNA containing single-strand breaks (SSBs).","definition_xrefs":["GOC:al","PMID:21984210"],"direct_ancestors":[{"relation_name":"is_a","term_name":"damaged DNA binding","termid":"GO:0003684"}],"gene_count":2,"genes_by_uniquename":{"SJAG_04410":null,"SJAG_16460":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003677"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0003674","GO:0005488","GO:0003677"],"is_obsolete":false,"name":"single-strand break-containing DNA binding","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"SSB-containing DNA binding","type":"exact"},{"name":"single-strand break-containing damaged DNA binding","type":"exact"}],"termid":"GO:1990165","terms_by_termid":{"GO:1990165":null}}


id: GO:0047430
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: H2O + oligosaccharide-diphosphodolichol = dolichol-phosphate + oligosaccharide phosphate.","definition_xrefs":["EC:3.6.1.44","MetaCyc:3.6.1.44-RXN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pyrophosphatase activity","termid":"GO:0016462"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"}],"interesting_parent_ids":["GO:0016787","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"oligosaccharide-diphosphodolichol diphosphatase activity","secondary_identifiers":["RHEA:15205"],"synonyms":[{"name":"oligosaccharide-diphosphodolichol phosphodolichohydrolase activity","type":"related"},{"name":"oligosaccharide-diphosphodolichol pyrophosphatase activity","type":"exact"}],"termid":"GO:0047430"}


id: GO:1904409
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of secretory granule organization.","definition_xrefs":["GOC:TermGenie","GO_REF:0000058","PMID:15039777"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of organelle organization","termid":"GO:0033043"},{"relation_name":"regulates","term_name":"secretory granule organization","termid":"GO:0033363"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of secretory granule organization","synonyms":[{"name":"regulation of secretory granule organisation","type":"exact"},{"name":"regulation of secretory granule organization and biogenesis","type":"related"}],"termid":"GO:1904409"}


id: PBO:0091692
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"O-methyltransferase, human COMT catechol homolog 1","termid":"PBO:0091692"}


id: GO:0097362
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A hexameric protein complex composed of MCM8 and MCM9 and involved in homologous recombination repair following DNA interstrand cross-links.","definition_xrefs":["PMID:22771115","PMID:22771120","GOC:sp"],"direct_ancestors":[{"relation_name":"is_a","term_name":"MCM complex","termid":"GO:0042555"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"MCM8-MCM9 complex","termid":"GO:0097362"}


id: PBO:0069210
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 465, pseudogene","termid":"PBO:0069210"}


id: GO:0071614
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of an NADPH- and oxygen-dependent reaction that converts linoleic acid to a cis-epoxyoctadecenoic acid.","definition_xrefs":["GOC:BHF","PMID:11042099"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monooxygenase activity","termid":"GO:0004497"},{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen","termid":"GO:0016705"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"linoleic acid epoxygenase activity","synonyms":[{"name":"linoleic acid monooxygenase activity","type":"exact"}],"termid":"GO:0071614"}


id: MONDO:0800413
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"inherited disease susceptibility","termid":"MONDO:0020573"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"antisocial behavior, susceptibility to","secondary_identifiers":["MEDGEN:934798","UMLS:C4310831"],"termid":"MONDO:0800413","xrefs":{"Monarch":{"xref_id":"0800413"}}}


id: GO:0003063
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which acetylcholine released from vagus nerve endings binds to muscarinic receptors on the pacemaker cells and decreases the rate of heart muscle contraction.","definition_xrefs":["GOC:mtg_cardio","GOC:rl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of heart rate by chemical signal","termid":"GO:0003062"},{"relation_name":"is_a","term_name":"negative regulation of heart rate","termid":"GO:0010459"},{"relation_name":"part_of","term_name":"regulation of systemic arterial blood pressure by acetylcholine","termid":"GO:0003068"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of heart rate by acetylcholine","synonyms":[{"name":"negative regulation of heart contraction rate by acetylcholine","type":"related"}],"termid":"GO:0003063"}


id: MONDO:0012696
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"otosclerosis","termid":"MONDO:0005349"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"otosclerosis 4","secondary_identifiers":["OMIM:611571","DOID:0060923","MESH:C566914","UMLS:C1969046","MEDGEN:369916"],"synonyms":[{"name":"OTSC4","type":"exact"},{"name":"otosclerosis 4","type":"exact"}],"termid":"MONDO:0012696","xrefs":{"Monarch":{"xref_id":"0012696"}}}


id: GO:0099011
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a neuronal dense core vesicle by fusion of the granule with the plasma membrane of a neuron in response to increased cytosolic calcium levels.","definition_xrefs":["PMID:17553987","GOC:kmv","PMID:24653208"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dense core granule exocytosis","termid":"GO:1990504"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0016192"}],"interesting_parent_ids":["GO:0008150","GO:0051179","GO:0016192","GO:0006810"],"is_obsolete":false,"name":"neuronal dense core vesicle exocytosis","termid":"GO:0099011"}


id: GO:0061223
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the mesonephros as it progresses from its formation to the mature state.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell differentiation involved in mesonephros development","termid":"GO:0061208"},{"relation_name":"is_a","term_name":"mesenchymal cell differentiation involved in kidney development","termid":"GO:0072161"},{"relation_name":"part_of","term_name":"mesonephric mesenchyme development","termid":"GO:0061219"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mesonephric mesenchymal cell differentiation","termid":"GO:0061223"}


id: PBO:0073176
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"selenoprotein H","termid":"PBO:0073176"}


id: _global:preceded_by
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.","direct_ancestors":[{"relation_name":"is_a","term_name":"ends_after","termid":"_global:ends_after"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"preceded_by","secondary_identifiers":["BFO:0000062"],"termid":"_global:preceded_by"}


id: PBO:0060335
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myosin VB","termid":"PBO:0060335"}


id: PBO:0044712
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DEAD/H-box helicase 11","termid":"PBO:0044712"}


id: GO:0001677
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator).","definition_xrefs":["GOC:hjd"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-RNA complex assembly","termid":"GO:0022618"},{"relation_name":"part_of","term_name":"translational initiation","termid":"GO:0006413"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0065003"},{"rel_name":"part_of","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0044085","GO:0065003","GO:0010467","GO:0008150"],"is_obsolete":false,"name":"formation of translation initiation ternary complex","synonyms":[{"name":"translation initiation ternary complex assembly","type":"exact"}],"termid":"GO:0001677"}


id: MONDO:0044878
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A germ cell tumor that occurs during adulthood.","definition_xrefs":["NCIT:C114777"],"direct_ancestors":[{"relation_name":"is_a","term_name":"germ cell tumor","termid":"MONDO:0005040"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"adult germ cell tumor","secondary_identifiers":["MEDGEN:859695","UMLS:C3900101"],"synonyms":[{"name":"Adult germ cell tumor","type":"exact"},{"name":"Adult germ cell tumour","type":"exact"},{"name":"germ cell tumor","type":"broad"},{"name":"germ cell tumor of adults","type":"exact"},{"name":"germ cell tumour","type":"broad"},{"name":"germ cell tumour of adults","type":"exact"}],"termid":"MONDO:0044878","xrefs":{"Monarch":{"xref_id":"0044878"}}}


id: PBO:0000859
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"S. pombe specific UPF0300 family protein 1","termid":"PBO:0000859"}


id: GO:0042856
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phenol-containing compound catabolic process","termid":"GO:0019336"},{"relation_name":"is_a","term_name":"eugenol metabolic process","termid":"GO:0042854"},{"relation_name":"is_a","term_name":"phenylpropanoid catabolic process","termid":"GO:0046271"},{"relation_name":"is_a","term_name":"olefinic compound catabolic process","termid":"GO:0120256"},{"relation_name":"is_a","term_name":"ether catabolic process","termid":"GO:1901502"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0019748"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0019748","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"eugenol catabolic process","synonyms":[{"name":"4-allyl-2-methoxyphenol catabolic process","type":"exact"},{"name":"4-allyl-2-methoxyphenol catabolism","type":"exact"},{"name":"eugenic acid catabolic process","type":"exact"},{"name":"eugenic acid catabolism","type":"exact"},{"name":"eugenol breakdown","type":"exact"},{"name":"eugenol catabolism","type":"exact"},{"name":"eugenol degradation","type":"exact"}],"termid":"GO:0042856"}


id: MONDO:0018267
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"combined dystonia","termid":"MONDO:0020065"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0003441"}],"interesting_parent_ids":["MONDO:0003441"],"is_obsolete":false,"name":"combined cervical dystonia","secondary_identifiers":["Orphanet:370114"],"termid":"MONDO:0018267","xrefs":{"Monarch":{"xref_id":"0018267"}}}


id: GO:0071012
data:
  {"annotated_genes":["SJAG_04783","SJAG_01504","SJAG_04117","SJAG_01315","SJAG_04898"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[79233,79671,62643,72594,75213],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0071006"}]},"cv_name":"cellular_component","definition":"A spliceosomal complex that is formed by the displacement of the two snRNPs from the precatalytic spliceosome; three snRNPs including U5 remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the associated snRNPs.","definition_xrefs":["GOC:krc","GOC:mah","GOC:ab","PMID:19239890","PMID:18322460"],"direct_ancestors":[{"relation_name":"is_a","term_name":"spliceosomal complex","termid":"GO:0005681"},{"relation_name":"is_a","term_name":"catalytic complex","termid":"GO:1902494"}],"gene_count":5,"genes_by_uniquename":{"SJAG_01315":null,"SJAG_01504":null,"SJAG_04117":null,"SJAG_04783":null,"SJAG_04898":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005634"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0032991","GO:0005634"],"is_obsolete":false,"name":"catalytic step 1 spliceosome","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000117":null},"synonyms":[{"name":"activated spliceosome","type":"exact"},{"name":"mammalian spliceosomal complex B*","type":"narrow"},{"name":"mammalian spliceosomal complex B2","type":"narrow"},{"name":"yeast spliceosomal complex A1","type":"narrow"}],"termid":"GO:0071012","terms_by_termid":{"GO:0071006":null}}


id: MONDO:0016685
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"astrocytoma (excluding glioblastoma)","termid":"MONDO:0019781"},{"relation_name":"is_a","term_name":"low grade astrocytic tumor","termid":"MONDO:0021638"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"low-grade astrocytoma","secondary_identifiers":["GARD:20706","UMLS:C1314694","Orphanet:251592","MedDRA:10065869","MEDGEN:727259"],"termid":"MONDO:0016685","xrefs":{"Monarch":{"xref_id":"0016685"}}}


id: MONDO:0004156
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A mucinous cystadenocarcinoma that involves the pancreas.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pancreatic cystadenocarcinoma","termid":"MONDO:0002867"},{"relation_name":"is_a","term_name":"mucinous cystadenocarcinoma","termid":"MONDO:0005858"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0004992"],"is_obsolete":false,"name":"pancreatic mucinous cystadenocarcinoma","secondary_identifiers":["DOID:7234","MEDGEN:1433902","NCIT:C5713","UMLS:C2063873"],"synonyms":[{"name":"colloid Cystadencarcinoma of pancreas","type":"exact"},{"name":"colloid Cystadencarcinoma of the pancreas","type":"exact"},{"name":"colloidal Cystadencarcinoma of pancreas","type":"exact"},{"name":"colloidal Cystadencarcinoma of the pancreas","type":"exact"},{"name":"mucinous Cystadencarcinoma of pancreas","type":"exact"},{"name":"mucinous Cystadencarcinoma of the pancreas","type":"exact"},{"name":"pancreatic colloid Cystadencarcinoma","type":"exact"},{"name":"pancreatic colloid cystadenocarcinoma","type":"related"},{"name":"pancreatic colloidal Cystadencarcinoma","type":"exact"},{"name":"pancreatic mucinous cystadenocarcinoma","type":"exact"}],"termid":"MONDO:0004156","xrefs":{"Monarch":{"xref_id":"0004156"}}}


id: PBO:0053497
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 475","termid":"PBO:0053497"}


id: GO:0160261
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: histone H1 L-asparagine + H2O = histone H1 L-aspartate + NH4+.","definition_xrefs":["PMID:40240600"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein asparagine deamidase activity","termid":"GO:0160260"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0016810"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"}],"interesting_parent_ids":["GO:0003824","GO:0016810","GO:0140096","GO:0016787","GO:0003674"],"is_obsolete":false,"name":"histone H1 asparagine deamidase activity","termid":"GO:0160261"}


id: PBO:0087167
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA polymerase III subunit C37","termid":"PBO:0087167"}


id: PBO:0111424
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"exocyst complex subunit Exo3","termid":"PBO:0111424"}


id: GO:0046757
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A form of viral release in which the nucleocapsid evaginates from the host endoplasmic reticulum membrane system, resulting in envelopment of the virus and cell lysis.","definition_xrefs":["ISBN:0072370319"],"gene_count":0,"genotype_count":0,"name":"obsolete lytic virus budding from ER membrane (obsolete GO:0046757)","synonyms":[{"name":"lytic ER membrane viral budding","type":"exact"},{"name":"lytic endoplasmic reticulum membrane viral budding","type":"exact"},{"name":"lytic viral budding from ER membrane","type":"exact"},{"name":"lytic virus budding from ER membrane","type":"exact"}],"termid":"GO:0046757"}


id: MONDO:0006550
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign polypoid lesion of mesodermal origin that arises from the urethra.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"skin tag","termid":"MONDO:0004026"},{"relation_name":"is_a","term_name":"urethral disorder","termid":"MONDO:0004184"},{"relation_name":"is_a","term_name":"fibroepithelial polyp","termid":"MONDO:0060765"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fibroepithelial polyp of urethra","secondary_identifiers":["MEDGEN:234460","DOID:8108","NCIT:C6170","UMLS:C1336884"],"synonyms":[{"name":"fibroepithelial polyp of the urethra","type":"exact"},{"name":"fibroepithelial polyp of urethra","type":"exact"},{"name":"skin tag of urethra","type":"related"},{"name":"urethra fibroepithelial polyp","type":"exact"},{"name":"urethra skin tag","type":"exact"},{"name":"urethral fibroepithelial polyp","type":"exact"}],"termid":"MONDO:0006550","xrefs":{"Monarch":{"xref_id":"0006550"}}}


id: MONDO:0006361
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete penile fibromatosis (obsolete MONDO:0006361)","secondary_identifiers":["EFO:1000466"],"termid":"MONDO:0006361","xrefs":{"Monarch":{"xref_id":"0006361"}}}


id: PBO:0120081
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CLN5 lysosomal BMP synthase","termid":"PBO:0120081"}


id: PBO:0057148
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 296","termid":"PBO:0057148"}


id: PBO:0058017
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 3943","termid":"PBO:0058017"}


id: PBO:0060830
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nectin cell adhesion molecule 4","termid":"PBO:0060830"}


id: MONDO:0022057
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A slow growing, locally invasive neoplasm arising from tooth-forming tissues. It most often grows intraosseously in the mandible and less frequently in the maxilla. In a minority of cases it grows extraosseously in the gingiva. It is characterized by the presence of a fibrous stroma, epithelial cells with abundant eosinophilic cytoplasm, and amyloid material which is often calcified. Small tumors may be successfully treated with enucleation. Local resection is usually required for larger tumors. Recurrences have been reported in a minority of cases.","definition_xrefs":["NCIT:C54301"],"direct_ancestors":[{"relation_name":"is_a","term_name":"skin neoplasm","termid":"MONDO:0002531"},{"relation_name":"is_a","term_name":"odontogenic neoplasm","termid":"MONDO:0021192"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"calcifying epithelial odontogenic tumor","secondary_identifiers":["MEDGEN:87266","ICDO:9340/0","MESH:C537961","UMLS:C0334574"],"synonyms":[{"name":"CEOT","type":"related"},{"name":"Pindborg tumor","type":"exact"},{"name":"Pindborg tumour","type":"exact"},{"name":"calcifying epithelial odontogenic tumor","type":"exact"}],"termid":"MONDO:0022057","xrefs":{"Monarch":{"xref_id":"0022057"}}}


id: PBO:0078696
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Leu (anticodon AAG) 7-1","termid":"PBO:0078696"}


id: GO:0002039
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to one of the p53 family of proteins.","definition_xrefs":["GOC:hjd"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein binding","termid":"GO:0005515"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005515"}],"interesting_parent_ids":["GO:0003674","GO:0005515","GO:0005488"],"is_obsolete":false,"name":"p53 binding","termid":"GO:0002039"}


id: GO:2000820
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any negative regulation of transcription from RNA polymerase II promoter that is involved in smooth muscle cell differentiation.","definition_xrefs":["GOC:BHF"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation (obsolete GO:2000820)","synonyms":[{"name":"down regulation of global transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation","type":"related"},{"name":"down regulation of global transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation","type":"related"},{"name":"down regulation of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation","type":"exact"},{"name":"down regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation","type":"exact"},{"name":"down-regulation of global transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation","type":"related"},{"name":"down-regulation of global transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation","type":"related"},{"name":"down-regulation of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation","type":"exact"},{"name":"down-regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation","type":"exact"},{"name":"downregulation of global transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation","type":"related"},{"name":"downregulation of global transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation","type":"related"},{"name":"downregulation of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation","type":"exact"},{"name":"downregulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation","type":"exact"},{"name":"inhibition of global transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation","type":"related"},{"name":"inhibition of global transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation","type":"related"},{"name":"inhibition of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation","type":"exact"},{"name":"inhibition of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation","type":"exact"},{"name":"negative regulation of gene-specific transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation","type":"related"},{"name":"negative regulation of gene-specific transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation","type":"related"},{"name":"negative regulation of global transcription from Pol II promoter involved in nonstriated muscle cell differentiation","type":"related"},{"name":"negative regulation of global transcription from Pol II promoter involved in smooth muscle cell differentiation","type":"related"},{"name":"negative regulation of transcription from Pol II promoter involved in nonstriated muscle cell differentiation","type":"exact"},{"name":"negative regulation of transcription from Pol II promoter involved in smooth muscle cell differentiation","type":"exact"},{"name":"negative regulation of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation","type":"exact"},{"name":"negative regulation of transcription from RNA polymerase II promoter, global involved in nonstriated muscle cell differentiation","type":"related"},{"name":"negative regulation of transcription from RNA polymerase II promoter, global involved in smooth muscle cell differentiation","type":"related"}],"termid":"GO:2000820"}


id: PBO:0053339
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 207","termid":"PBO:0053339"}


id: GO:0052618
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: GTP + L-glutamate + factor F420-0 = GDP + H+ + factor gamma-F420-1 + phosphate.","definition_xrefs":["MetaCyc:RXN-8080"],"direct_ancestors":[{"relation_name":"is_a","term_name":"coenzyme F420-0 gamma-glutamyl ligase activity","termid":"GO:0043773"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016874"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0016874","GO:0003824"],"is_obsolete":false,"name":"coenzyme F420-0:L-glutamate ligase activity","secondary_identifiers":["RHEA:30555","EC:6.3.2.31"],"termid":"GO:0052618"}


id: GO:1905449
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis.","definition_xrefs":["GO_REF:0000058","GOC:TermGenie","PMID:18832707"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of immune effector process","termid":"GO:0002697"},{"relation_name":"is_a","term_name":"regulation of Fc receptor mediated stimulatory signaling pathway","termid":"GO:0060368"},{"relation_name":"regulates","term_name":"Fc-gamma receptor signaling pathway involved in phagocytosis","termid":"GO:0038096"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"regulation of Fc-gamma receptor signaling pathway involved in phagocytosis","synonyms":[{"name":"regulation of Fc gamma receptor-dependent phagocytosis","type":"exact"},{"name":"regulation of Fc-gamma receptor signalling pathway involved in phagocytosis","type":"exact"},{"name":"regulation of Fcgamma receptor-mediated phagocytosis","type":"exact"},{"name":"regulation of IgG-mediated phagocytosis","type":"exact"}],"termid":"GO:1905449"}


id: MONDO:1010104
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Trimethylaminuria (fishy taint) that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inborn errors of metabolism, non-human animal","termid":"MONDO:1012979"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"trimethylaminuria (fishy taint), non-human animal","secondary_identifiers":["OMIA:001360"],"termid":"MONDO:1010104","xrefs":{"Monarch":{"xref_id":"1010104"}}}


id: GO:1900484
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to vacuolar membrane.","definition_xrefs":["GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of protein targeting to membrane","termid":"GO:0090315"},{"relation_name":"is_a","term_name":"negative regulation of intracellular protein transport","termid":"GO:0090317"},{"relation_name":"is_a","term_name":"regulation of protein targeting to vacuolar membrane","termid":"GO:1900483"},{"relation_name":"is_a","term_name":"negative regulation of vacuolar transport","termid":"GO:1903336"},{"relation_name":"is_a","term_name":"negative regulation of protein localization to membrane","termid":"GO:1905476"},{"relation_name":"negatively_regulates","term_name":"protein targeting to vacuolar membrane","termid":"GO:0044395"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006605"},{"rel_name":"negatively_regulates","termid":"GO:0006605"},{"rel_name":"negatively_regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810","GO:0006605"],"is_obsolete":false,"name":"negative regulation of protein targeting to vacuolar membrane","synonyms":[{"name":"down regulation of protein targeting to vacuolar membrane","type":"exact"},{"name":"down-regulation of protein targeting to vacuolar membrane","type":"exact"},{"name":"downregulation of protein targeting to vacuolar membrane","type":"exact"},{"name":"inhibition of protein targeting to vacuolar membrane","type":"narrow"}],"termid":"GO:1900484"}


id: GO:0072664
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process in which a protein is maintained in a specific location in a peroxisome, and is prevented from moving elsewhere.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"maintenance of protein localization in organelle","termid":"GO:0072595"},{"relation_name":"part_of","term_name":"protein localization to peroxisome","termid":"GO:0072662"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0007031"}],"interesting_parent_ids":["GO:0007031","GO:0051179","GO:0008150"],"is_obsolete":false,"name":"maintenance of protein location in peroxisome","termid":"GO:0072664"}


id: GO:0005791
data:
  {"annotated_genes":["SJAG_00175","SJAG_02208","SJAG_00064","SJAG_00959","SJAG_02354","SJAG_01558","SJAG_03955","SJAG_00360","SJAG_02588","SJAG_02330"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[111182,107997,99859,64927],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0005784"},{"annotations":[111471,92394,97549,74904],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0031207"},{"annotations":[70541,96087],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0005785"},{"annotations":[110149,99860],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0071261"}]},"cv_name":"cellular_component","definition":"The rough (or granular) endoplasmic reticulum (ER) has ribosomes adhering to the outer surface; the ribosomes are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from the cell. Glycoproteins undergo their initial glycosylation within the cisternae.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"endoplasmic reticulum","termid":"GO:0005783"}],"gene_count":10,"genes_by_uniquename":{"SJAG_00064":null,"SJAG_00175":null,"SJAG_00360":null,"SJAG_00959":null,"SJAG_01558":null,"SJAG_02208":null,"SJAG_02330":null,"SJAG_02354":null,"SJAG_02588":null,"SJAG_03955":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005783"}],"interesting_parent_ids":["GO:0005783","GO:0005575","GO:0005737"],"is_obsolete":false,"name":"rough endoplasmic reticulum","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["NIF_Subcellular:sao1881364067","Wikipedia:Endoplasmic_reticulum#Rough_endoplasmic_reticulum"],"synonyms":[{"name":"RER","type":"exact"},{"name":"rough ER","type":"exact"}],"termid":"GO:0005791","terms_by_termid":{"GO:0005784":null,"GO:0005785":null,"GO:0031207":null,"GO:0071261":null}}


id: PBO:0077594
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane serine protease 5","termid":"PBO:0077594"}


id: GO:0046252
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products.","definition_xrefs":["GOC:ai","PMID:6508079"],"direct_ancestors":[{"relation_name":"is_a","term_name":"toluene metabolic process","termid":"GO:0018970"},{"relation_name":"is_a","term_name":"hydrocarbon biosynthetic process","termid":"GO:0120251"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"toluene biosynthetic process","synonyms":[{"name":"toluene anabolism","type":"exact"},{"name":"toluene biosynthesis","type":"exact"},{"name":"toluene formation","type":"exact"},{"name":"toluene synthesis","type":"exact"}],"termid":"GO:0046252"}


id: PBO:0084574
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Membrane protein of unknown function; overexpression suppresses NaCl sensitivity of sro7 mutant cells by restoring sodium pump (Ena1p) localization to the plasma membrane","termid":"PBO:0084574"}


id: GO:0047595
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 1,4,5,6-tetrahydro-6-oxonicotinate + oxidized ferredoxin = 6-hydroxynicotinate + reduced ferredoxin.","definition_xrefs":["EC:1.3.7.1","MetaCyc:6-HYDROXYNICOTINATE-REDUCTASE-RXN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor","termid":"GO:0016636"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"6-hydroxynicotinate reductase activity","secondary_identifiers":["RHEA:17225"],"synonyms":[{"name":"1,4,5,6-tetrahydro-6-oxonicotinate:ferredoxin oxidoreductase activity","type":"related"},{"name":"6-hydroxynicotinic reductase activity","type":"related"},{"name":"6-oxo-1,4,5,6-tetrahydronicotinate:ferredoxin oxidoreductase activity","type":"related"},{"name":"6-oxotetrahydro-nicotinate dehydrogenase activity","type":"related"},{"name":"6-oxotetrahydronicotinate dehydrogenase activity","type":"related"},{"name":"HNA reductase activity","type":"related"}],"termid":"GO:0047595"}


id: PATO:0000534
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000534 p h sensitivity value (obsolete PATO:0000534)","termid":"PATO:0000534"}


id: PBO:0031798
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_duration_of_mitotic_G2/M_phase_transition_(obsolete_FYPO:0000403)","termid":"PBO:0031798"}


id: PBO:0089799
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosome biogenesis protein Tma23","termid":"PBO:0089799"}


id: FYPO:0000020
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell morphology phenotype in which a cell is shaped in the form of a pear. One end is rounded, while the other resembles an end of a normal rod-shaped cell. The normally shaped end has the same diameter as a wild-type cell.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal cell shape","termid":"FYPO:0001126"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000005"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0000005"],"is_obsolete":false,"name":"pear-shaped cell","synonyms":[{"name":"cell morphology, pear shaped","type":"exact"},{"name":"ice cream cone-shaped cell","type":"exact"}],"termid":"FYPO:0000020"}


id: MONDO:0021325
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A cancer that involves the thoracic part of esophagus.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"esophageal cancer","termid":"MONDO:0007576"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0004335"],"is_obsolete":false,"name":"malignant neoplasm of thoracic esophagus","secondary_identifiers":["MEDGEN:102268","SCTID:187723009","UMLS:C0153411","ICD9:150.1","NCIT:C3532"],"synonyms":[{"name":"cancer of thoracic part of esophagus","type":"exact"},{"name":"cancer of thoracic part of oesophagus","type":"exact"},{"name":"malignant neoplasm of the thoracic esophagus","type":"exact"},{"name":"malignant neoplasm of the thoracic oesophagus","type":"exact"},{"name":"malignant neoplasm of thoracic part of esophagus","type":"exact"},{"name":"malignant neoplasm of thoracic part of oesophagus","type":"exact"},{"name":"malignant thoracic part of esophagus neoplasm","type":"exact"},{"name":"malignant thoracic part of oesophagus neoplasm","type":"exact"},{"name":"thoracic part of esophagus cancer","type":"exact"},{"name":"thoracic part of oesophagus cancer","type":"exact"}],"termid":"MONDO:0021325","xrefs":{"Monarch":{"xref_id":"0021325"}}}


id: GO:0016143
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sulfur compound metabolic process","termid":"GO:0006790"},{"relation_name":"is_a","term_name":"glycosyl compound metabolic process","termid":"GO:1901657"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006790"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006790","GO:0008150"],"is_obsolete":false,"name":"S-glycoside metabolic process","synonyms":[{"name":"S-glycoside metabolism","type":"exact"},{"name":"thioglycoside metabolic process","type":"exact"},{"name":"thioglycoside metabolism","type":"exact"}],"termid":"GO:0016143"}


id: MONDO:0003870
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An astrocytoma that arises from the brain stem and occurs during childhood.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"childhood astrocytic tumor","termid":"MONDO:0002505"},{"relation_name":"is_a","term_name":"brain stem astrocytic neoplasm","termid":"MONDO:0003173"},{"relation_name":"is_a","term_name":"childhood brain stem glioma","termid":"MONDO:0003869"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"childhood brainstem astrocytoma","secondary_identifiers":["DOID:6386","MEDGEN:234123","NCIT:C6216","UMLS:C1332950"],"synonyms":[{"name":"brain stem astrocytic neoplasm of childhood","type":"exact"},{"name":"childhood brain stem astrocytic neoplasm","type":"exact"},{"name":"childhood brain stem astrocytoma","type":"exact"},{"name":"childhood brainstem astrocytoma","type":"exact"},{"name":"paediatric brain stem astrocytic neoplasm","type":"exact"},{"name":"pediatric brain stem astrocytic neoplasm","type":"exact"}],"termid":"MONDO:0003870","xrefs":{"Monarch":{"xref_id":"0003870"}}}


id: PBO:0062623
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 11 subfamily G member 2","termid":"PBO:0062623"}


id: MONDO:0005007
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An invasive adenocarcinoma of the colon characterized by the presence of pools of extracellular mucin. Malignant glandular epithelial cells are present in the mucin collections. Mucin constitutes more than 50% of the lesion.","definition_xrefs":["NCIT:C7966"],"direct_ancestors":[{"relation_name":"is_a","term_name":"colon adenocarcinoma","termid":"MONDO:0002271"},{"relation_name":"is_a","term_name":"mucinous adenocarcinoma","termid":"MONDO:0004957"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0004992"],"is_obsolete":false,"name":"colon mucinous adenocarcinoma","secondary_identifiers":["EFO:0000364","MEDGEN:76007","DOID:3029","UMLS:C0279639"],"synonyms":[{"name":"colloid adenocarcinoma of colon","type":"exact"},{"name":"colloid adenocarcinoma of the colon","type":"exact"},{"name":"colloid colon adenocarcinoma","type":"exact"},{"name":"colloidal adenocarcinoma of colon","type":"exact"},{"name":"colloidal adenocarcinoma of the colon","type":"exact"},{"name":"colloidal colon adenocarcinoma","type":"exact"},{"name":"colon colloid adenocarcinoma","type":"exact"},{"name":"colon colloidal adenocarcinoma","type":"exact"},{"name":"colon mucinous adenocarcinoma","type":"exact"},{"name":"colonic colloid adenocarcinoma","type":"exact"},{"name":"colonic colloidal adenocarcinoma","type":"exact"},{"name":"colonic mucinous adenocarcinoma","type":"exact"},{"name":"mucinous adenocarcinoma of colon","type":"exact"},{"name":"mucinous adenocarcinoma of the colon","type":"exact"},{"name":"mucinous colon adenocarcinoma","type":"exact"}],"termid":"MONDO:0005007","xrefs":{"Monarch":{"xref_id":"0005007"}}}


id: MONDO:0010103
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"teeth, fused","secondary_identifiers":["MESH:D005671","SCTID:1744008","UMLS:C0016873","MEDGEN:4808","OMIM:273000"],"synonyms":[{"name":"teeth, fused","type":"exact"}],"termid":"MONDO:0010103","xrefs":{"Monarch":{"xref_id":"0010103"}}}


id: PBO:0015242
data:
  {"annotation_feature_type":"gene","cv_name":"subunit_composition","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"homomeric(4)","termid":"PBO:0015242"}


id: MONDO:0002006
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A labyrinthitits in which bacterial toxins invade the inner ear. It is the most common complication of acute or chronic middle ear infections.","definition_xrefs":["DOID:1467"],"direct_ancestors":[{"relation_name":"is_a","term_name":"labyrinthitis","termid":"MONDO:0002008"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serous labyrinthitis","secondary_identifiers":["UMLS:C0155504","SCTID:41674001","ICD9:386.31","MEDGEN:509993"],"synonyms":[{"name":"acute serous labyrinthitis","type":"exact"}],"termid":"MONDO:0002006","xrefs":{"Monarch":{"xref_id":"0002006"}}}


id: MONDO:0014723
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"partial duplication of the long arm of chromosome 17","termid":"MONDO:0016967"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PMP22-RAI1 contiguous gene duplication syndrome","secondary_identifiers":["Orphanet:477817","GARD:17859","OMIM:616652","MEDGEN:894862","UMLS:C4225255"],"synonyms":[{"name":"17p11.2p12 microduplication syndrome","type":"exact"},{"name":"YUAN-Harel-Lupski syndrome","type":"related"},{"name":"YUHAL","type":"exact"},{"name":"Yuan-Harel-Lupski syndrome","type":"exact"},{"name":"dup(17)(p11.2p12)","type":"exact"},{"name":"trisomy 17p11.2-p12","type":"exact"},{"name":"trisomy 17p11.2p12","type":"exact"}],"termid":"MONDO:0014723","xrefs":{"Monarch":{"xref_id":"0014723"}}}


id: MONDO:0003075
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Retinoblastoma involving both eyes. This occurs in the majority of patients with the inherited variant. A minority of patient with bilateral retinoblastoma were found to have involvement of the pineal gland as well.","definition_xrefs":["NCIT:C8713"],"direct_ancestors":[{"relation_name":"is_a","term_name":"retinoblastoma","termid":"MONDO:0008380"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0005328"],"is_obsolete":false,"name":"bilateral retinoblastoma","secondary_identifiers":["DOID:4650","MEDGEN:163163","NANDO:2201038","UMLS:C0854914"],"termid":"MONDO:0003075","xrefs":{"Monarch":{"xref_id":"0003075"}}}


id: MONDO:0032860
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive non-syndromic intellectual disability","termid":"MONDO:0019502"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0037792"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0005066","MONDO:0037792"],"is_obsolete":false,"name":"intellectual developmental disorder, autosomal recessive 72","secondary_identifiers":["UMLS:C5231452","OMIM:618665","DOID:0080765","MEDGEN:1684805"],"synonyms":[{"name":"INTELLECTUAL DEVELOPMENTAL DISORDER, AUTOSOMAL RECESSIVE 72","type":"related"},{"name":"MRT72","type":"related"},{"name":"Mental Retardation, Autosomal Recessive 72","type":"related"}],"termid":"MONDO:0032860","xrefs":{"Monarch":{"xref_id":"0032860"}}}


id: PBO:0087680
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of the mitochondrial (mt) i-AAA protease supercomplex; i-AAA degrades misfolded mitochondrial proteins; forms a subcomplex with Mgr1p that binds to substrates to facilitate proteolysis; required for growth of cells lacking mtDNA","termid":"PBO:0087680"}


id: PBO:0030403
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_potassium_chloride","termid":"PBO:0030403"}


id: MONDO:0016840
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Trisomy 17p is a rare chromosomal abnormality resulting from the duplication of the short arm of chromosome 17 and characterized by pre- and post-natal growth retardation, developmental delay, hypotonia, digital abnormalities, congenital heart defects, and distinctive facial features.","definition_xrefs":["Orphanet:261290"],"direct_ancestors":[{"relation_name":"is_a","term_name":"partial duplication of the short arm of chromosome 17","termid":"MONDO:0016950"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"trisomy 17p","secondary_identifiers":["GARD:5318","UMLS:C0795865","MESH:C538048","SCTID:717049005","MEDGEN:167078"],"synonyms":[{"name":"17p duplication","type":"related"},{"name":"17p trisomy","type":"related"},{"name":"Duplication 17p","type":"related"},{"name":"chromosome 17p duplication","type":"related"},{"name":"dup(17p)","type":"exact"},{"name":"partial trisomy 17p","type":"related"},{"name":"trisomy type 17p","type":"exact"}],"termid":"MONDO:0016840","xrefs":{"Monarch":{"xref_id":"0016840"}}}


id: GO:0120159
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: a uridine in rRNA = a pseudouridine in rRNA. Conversion of uridine in an rRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.","definition_xrefs":["PMID:28432181","RHEA:54568"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pseudouridine synthase activity","termid":"GO:0009982"},{"relation_name":"is_a","term_name":"catalytic activity, acting on RNA","termid":"GO:0140098"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016853"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0140098","GO:0016853","GO:0003824"],"is_obsolete":false,"name":"rRNA pseudouridine synthase activity","termid":"GO:0120159"}


id: PBO:0061312
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NPHP3 antisense RNA 1","termid":"PBO:0061312"}


id: GO:0002723
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate, or extent of B cell cytokine production.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of B cell mediated immunity","termid":"GO:0002714"},{"relation_name":"is_a","term_name":"positive regulation of cytokine production involved in immune response","termid":"GO:0002720"},{"relation_name":"is_a","term_name":"regulation of B cell cytokine production","termid":"GO:0002721"},{"relation_name":"positively_regulates","term_name":"B cell cytokine production","termid":"GO:0002368"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0010467"},{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"positive regulation of B cell cytokine production","synonyms":[{"name":"activation of B cell cytokine production","type":"narrow"},{"name":"positive regulation of B lymphocyte cytokine production","type":"exact"},{"name":"positive regulation of B-cell cytokine production","type":"exact"},{"name":"positive regulation of B-lymphocyte cytokine production","type":"exact"},{"name":"stimulation of B cell cytokine production","type":"narrow"},{"name":"up regulation of B cell cytokine production","type":"exact"},{"name":"up-regulation of B cell cytokine production","type":"exact"},{"name":"upregulation of B cell cytokine production","type":"exact"}],"termid":"GO:0002723"}


id: MONDO:1040011
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A human disorder which results from a tear in one of the major cervicocerebral arteries, allowing blood to enter the wall of the artery and split its layers. Pathogenesis typically leads to either stenosis or aneurysmal dilatation of the vessel.","definition_xrefs":["PMID:19096659","PMID:28722857"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cervical artery dissection","termid":"MONDO:0006061"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vertebral artery dissection","synonyms":[{"name":"VAD","type":"exact"}],"termid":"MONDO:1040011","xrefs":{"Monarch":{"xref_id":"1040011"}}}


id: GO:0018422
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the transfer of mannose-1-phosphate to a serine residue in a protein.","definition_xrefs":["PMID:10037765","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphotransferase activity, for other substituted phosphate groups","termid":"GO:0016780"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016780"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0016780","GO:0003824","GO:0016740"],"is_obsolete":false,"name":"GDP-mannose:serine-protein mannose-1-phosphotransferase activity","termid":"GO:0018422"}


id: PBO:0060362
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myomesin 1","termid":"PBO:0060362"}


id: PBO:0025534
data:
  {"annotation_feature_type":"gene","cv_name":"disease_associated","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hypophosphatasia","termid":"PBO:0025534"}


id: PBO:0070818
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L12 pseudogene 48","termid":"PBO:0070818"}


id: PBO:0058044
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4265","termid":"PBO:0058044"}


id: GO:0016128
data:
  {"annotated_genes":["SJAG_00717","SJAG_04499","SJAG_00770","SJAG_02719","SJAG_02855","SJAG_04049","SJAG_04270","SJAG_00624","SJAG_03750","SJAG_04790","SJAG_02068","SJAG_02104","SJAG_04059","SJAG_03929","SJAG_03598","SJAG_00413","SJAG_03531","SJAG_00453","SJAG_02044","SJAG_03024","SJAG_04217","SJAG_02982","SJAG_03018","SJAG_03235","SJAG_04810","SJAG_01474","SJAG_01307","SJAG_03509","SJAG_00370","SJAG_00158","SJAG_03249","SJAG_03715","SJAG_04018"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[73483,90290,109679,72662,75702,82077,111089,111931,73279,82051,78236,77879,78972,71591,109365,67130,81865,96447,91475,117091,74898,78244,76047,118404],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006696"},{"annotations":[78051,82043,105175,105816,116933],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008204"},{"annotations":[95694],"is_not":false,"rel_names":["negatively_regulates","regulates"],"summary":null,"term":"GO:0010895"},{"annotations":[111697],"is_not":false,"rel_names":["positively_regulates","regulates"],"summary":null,"term":"GO:0070452"},{"annotations":[107666,90379],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0032443"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving phytosteroids, steroids of higher plants that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi.","definition_xrefs":["ISBN:0198547684","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"steroid metabolic process","termid":"GO:0008202"}],"gene_count":33,"genes_by_uniquename":{"SJAG_00158":null,"SJAG_00370":null,"SJAG_00413":null,"SJAG_00453":null,"SJAG_00624":null,"SJAG_00717":null,"SJAG_00770":null,"SJAG_01307":null,"SJAG_01474":null,"SJAG_02044":null,"SJAG_02068":null,"SJAG_02104":null,"SJAG_02719":null,"SJAG_02855":null,"SJAG_02982":null,"SJAG_03018":null,"SJAG_03024":null,"SJAG_03235":null,"SJAG_03249":null,"SJAG_03509":null,"SJAG_03531":null,"SJAG_03598":null,"SJAG_03715":null,"SJAG_03750":null,"SJAG_03929":null,"SJAG_04018":null,"SJAG_04049":null,"SJAG_04059":null,"SJAG_04217":null,"SJAG_04270":null,"SJAG_04499":null,"SJAG_04790":null,"SJAG_04810":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0006629","GO:0008150"],"is_obsolete":false,"name":"phytosteroid metabolic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000104":null,"GO_REF:0000107":null},"synonyms":[{"name":"phytosteroid metabolism","type":"exact"}],"termid":"GO:0016128","terms_by_termid":{"GO:0006696":null,"GO:0008204":null,"GO:0010895":null,"GO:0032443":null,"GO:0070452":null}}


id: GO:0004874
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Combining with an aryl hydrocarbon and transmitting the signal to initiate a change in cell activity. The aryl hydrocarbon receptor is a ligand-activated transcription factor which translocates to the nucleus to activate transcription upon ligand-binding.","definition_xrefs":["GOC:ai","PMID:1325649","Wikipedia:Aryl_hydrocarbon_receptor","PMID:7493958"],"gene_count":0,"genotype_count":0,"name":"obsolete aryl hydrocarbon receptor activity (obsolete GO:0004874)","termid":"GO:0004874"}


id: MONDO:1012022
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"spontaneous autoimmune thyroiditis, non-human animal","termid":"MONDO:1011673"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spontaneous autoimmune thyroiditis, domestic cat","secondary_identifiers":["OMIA:000097-9685"],"termid":"MONDO:1012022","xrefs":{"Monarch":{"xref_id":"1012022"}}}


id: GO:0047823
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: D-glutamate + D-glutamine = gamma-D-glutamyl-D-glutamate + NH4+. Can also transfer additional glutamyl residues to a peptide, extending the polypeptide chain.","definition_xrefs":["EC:2.3.2.1"],"direct_ancestors":[{"relation_name":"is_a","term_name":"aminoacyltransferase activity","termid":"GO:0016755"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016740","GO:0003824","GO:0016746","GO:0003674"],"is_obsolete":false,"name":"D-glutamyltransferase activity","secondary_identifiers":["MetaCyc:D-GLUTAMYLTRANSFERASE-RXN","RHEA:35623"],"synonyms":[{"name":"D-gamma-glutamyl transpeptidase activity","type":"related"},{"name":"D-glutamyl transpeptidase activity","type":"related"},{"name":"glutamine:D-glutamyl-peptide 5-glutamyltransferase activity","type":"related"}],"termid":"GO:0047823"}


id: GO:0032483
data:
  {"annotated_genes":["SJAG_03488","SJAG_04329"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[71748,76616],"is_not":false,"summary":null,"term":"GO:0032483"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of Rab protein signal transduction.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of small GTPase mediated signal transduction","termid":"GO:0051056"},{"relation_name":"regulates","term_name":"Rab protein signal transduction","termid":"GO:0032482"}],"gene_count":2,"genes_by_uniquename":{"SJAG_03488":null,"SJAG_04329":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"regulation of Rab protein signal transduction","references_by_uniquename":{"GO_REF:0000033":null},"termid":"GO:0032483","terms_by_termid":{"GO:0032483":null}}


id: GO:0090657
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The telomere maintenance process in which telomeric loops are disassembled to permit efficient telomere replication.","definition_xrefs":["GOC:BHF_telomere","PMID:22579284","GOC:BHF","GOC:nc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"telomere maintenance","termid":"GO:0000723"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006259"},{"rel_name":"is_a","termid":"GO:0032200"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0032200","GO:0008150","GO:0006259"],"is_obsolete":false,"name":"telomeric loop disassembly","synonyms":[{"name":"T loop disassembly","type":"exact"},{"name":"t-loop disassembly","type":"exact"}],"termid":"GO:0090657"}


id: PBO:0061447
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nuclear receptor subfamily 3 group C member 1 pseudogene 1","termid":"PBO:0061447"}


id: FYPO:0006691
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"OBSOLETE. A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell proceeds through the mitotic metaphase/anaphase transition in the presence of an uncorrected problem (such as chromosome structure or kinetochore attachment), and as a result undergoes abnormal nuclear envelope partitioning and subsequently dies.","definition_xrefs":["PomBase:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete mitotic catastrophe with abnormal nuclear envelope partitioning (obsolete FYPO:0006691)","synonyms":[{"name":"cut-like","type":"related"},{"name":"mitotic catastrophe with abnormal nuclear envelope partitioning during mitotic cell cycle","type":"related"},{"name":"mitotic catastrophe with abnormal nuclear envelope partitioning during vegetative growth","type":"exact"}],"termid":"FYPO:0006691"}


id: PBO:0070798
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L12 pseudogene 28","termid":"PBO:0070798"}


id: PBO:0076531
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"taste 2 receptor member 45","termid":"PBO:0076531"}


id: PBO:0000822
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BSD domain protein, unknown biological role","termid":"PBO:0000822"}


id: PBO:0001679
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mediator complex subunit Med11 (predicted)","termid":"PBO:0001679"}


id: PBO:0066363
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RD3 like","termid":"PBO:0066363"}


id: MONDO:0015719
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Severe hemophilia A is a form of hemophilia A characterized by a large deficiency of factor VIII leading to frequent spontaneous hemorrhage and abnormal bleeding as a result of minor injuries, or following surgery or tooth extraction.","definition_xrefs":["Orphanet:169802"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hemophilia A","termid":"MONDO:0010602"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"severe hemophilia A","secondary_identifiers":["GARD:17059","MEDGEN:543973","SCTID:16872008","UMLS:C0272322"],"synonyms":[{"name":"severe factor VIII deficiency","type":"exact"},{"name":"severe haemophilia type A","type":"exact"},{"name":"severe hemophilia type A","type":"exact"}],"termid":"MONDO:0015719","xrefs":{"Monarch":{"xref_id":"0015719"}}}


id: GO:0050810
data:
  {"annotated_genes":["SJAG_01307","SJAG_02044","SJAG_02104","SJAG_04018"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[95694],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010895"},{"annotations":[111697],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070452"},{"annotations":[77234],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0045540"},{"annotations":[90379,107666],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0032443"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of steroid metabolic process","termid":"GO:0019218"},{"relation_name":"is_a","term_name":"regulation of lipid biosynthetic process","termid":"GO:0046890"},{"relation_name":"regulates","term_name":"steroid biosynthetic process","termid":"GO:0006694"}],"gene_count":4,"genes_by_uniquename":{"SJAG_01307":null,"SJAG_02044":null,"SJAG_02104":null,"SJAG_04018":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0008150","GO:0006629"],"is_obsolete":false,"name":"regulation of steroid biosynthetic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"regulation of steroid anabolism","type":"exact"},{"name":"regulation of steroid biosynthesis","type":"exact"},{"name":"regulation of steroid formation","type":"exact"},{"name":"regulation of steroid synthesis","type":"exact"},{"name":"regulation of steroidogenesis","type":"exact"}],"termid":"GO:0050810","terms_by_termid":{"GO:0010895":null,"GO:0032443":null,"GO:0045540":null,"GO:0070452":null}}


id: PBO:0042969
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coiled-coil-helix-coiled-coil-helix domain containing 6","termid":"PBO:0042969"}


id: PBO:0038462
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP binding cassette subfamily A member 2","termid":"PBO:0038462"}


id: MONDO:0012405
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any hereditary mixed polyposis syndrome in which the cause of the disease is a mutation in the BMPR1A gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary mixed polyposis syndrome","termid":"MONDO:0011023"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"polyposis syndrome, hereditary mixed, 2","secondary_identifiers":["MEDGEN:350500","OMIM:610069","UMLS:C1864730","MESH:C566451","DOID:0111686","GARD:18276"],"synonyms":[{"name":"BMPR1A hereditary mixed polyposis syndrome","type":"exact"},{"name":"HMPS2","type":"related"},{"name":"hereditary mixed polyposis syndrome caused by mutation in BMPR1A","type":"exact"},{"name":"polyposis syndrome, hereditary mixed, 2","type":"exact"},{"name":"polyposis syndrome, hereditary mixed, type 2","type":"exact"}],"termid":"MONDO:0012405","xrefs":{"Monarch":{"xref_id":"0012405"}}}


id: MONDO:0013620
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any congenital myasthenic syndrome in which the cause of the disease is a mutation in the SCN4A gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"postsynaptic congenital myasthenic syndrome","termid":"MONDO:0020344"},{"relation_name":"is_a","term_name":"SCN4A-related myopathy, autosomal recessive","termid":"MONDO:0100121"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"},{"rel_name":"is_a","termid":"MONDO:0005336"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0002320","MONDO:0005336","MONDO:0006025"],"is_obsolete":false,"name":"congenital myasthenic syndrome 16","secondary_identifiers":["UMLS:C3280112","GARD:15771","DOID:0110682","MEDGEN:481742","OMIM:614198"],"synonyms":[{"name":"CMS16","type":"exact"},{"name":"SCN4A congenital myasthenic syndrome","type":"exact"},{"name":"congenital myasthenic syndrome acetazolamide-responsive","type":"exact"},{"name":"congenital myasthenic syndrome caused by mutation in SCN4A","type":"exact"},{"name":"congenital myasthenic syndrome type 16","type":"exact"},{"name":"myasthenic syndrome, congenital, 16","type":"related"},{"name":"myasthenic syndrome, congenital, Acetazolamide-responsive","type":"related"},{"name":"myasthenic syndrome, congenital, type 16","type":"exact"}],"termid":"MONDO:0013620","xrefs":{"Monarch":{"xref_id":"0013620"}}}


id: SO:0001661
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A TATA box core promoter of a gene transcribed by RNA polymerase II.","definition_xrefs":["PMID:16858867"],"direct_ancestors":[{"relation_name":"is_a","term_name":"TATA_box","termid":"SO:0000174"},{"relation_name":"part_of","term_name":"RNApol_II_core_promoter","termid":"SO:0001669"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA_polymerase_II_TATA_box","synonyms":[{"name":"RNA polymerase II TATA box","type":"exact"}],"termid":"SO:0001661"}


id: GO:0098807
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that is part of a chloroplast thylakoid membrane.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"membrane protein complex","termid":"GO:0098796"},{"relation_name":"part_of","term_name":"chloroplast thylakoid membrane","termid":"GO:0009535"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0032991","GO:0005575","GO:0005737"],"is_obsolete":false,"name":"chloroplast thylakoid membrane protein complex","termid":"GO:0098807"}


id: MONDO:0001488
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"corneal deposit","termid":"MONDO:0001308"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"anterior corneal pigmentation","secondary_identifiers":["DOID:12307","SCTID:18377001","ICD9:371.11","MEDGEN:509790","ICD10CM:H18.01","UMLS:C0155104"],"synonyms":[{"name":"anterior corneal pigmentations","type":"exact"}],"termid":"MONDO:0001488","xrefs":{"Monarch":{"xref_id":"0001488"}}}


id: PBO:0034270
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-function_of","termid":"PBO:0034270"}


id: MONDO:0011539
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Amish nemaline myopathy is a type of nemaline myopathy (NM) only observed in several families of the Amish community.","definition_xrefs":["Orphanet:98902"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nemaline myopathy","termid":"MONDO:0018958"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0005336"],"is_obsolete":false,"name":"nemaline myopathy 5","secondary_identifiers":["OMIM:605355","DOID:0110936","MEDGEN:344273","UMLS:C1854380","MESH:C538397","GARD:8334"],"synonyms":[{"name":"ANM","type":"exact"},{"name":"Amish nemaline myopathy","type":"exact"},{"name":"NEM5","type":"exact"},{"name":"TNNT1 nemaline myopathy","type":"exact"},{"name":"nemaline myopathy 5","type":"exact"},{"name":"nemaline myopathy 5, Amish type","type":"exact"},{"name":"nemaline myopathy caused by mutation in TNNT1","type":"exact"},{"name":"nemaline myopathy type 5","type":"exact"},{"name":"nemaline myopathy, Amish type","type":"related"},{"name":"nemaline myopathy, caused by mutation in the troponin t1 gene","type":"related"}],"termid":"MONDO:0011539","xrefs":{"Monarch":{"xref_id":"0011539"}}}


id: GO:0141215
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: N-acetyltaurine + H2O = acetate + taurine.","definition_xrefs":["PMID:39112712","RHEA:81107"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, acting on ester bonds","termid":"GO:0016788"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016787","GO:0003824","GO:0016788","GO:0003674"],"is_obsolete":false,"name":"N-acetyltaurine hydrolase activity","termid":"GO:0141215"}


id: MONDO:0014147
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any neuronal ceroid lipofuscinosis in which the cause of the disease is a mutation in the CTSF gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"adult neuronal ceroid lipofuscinosis","termid":"MONDO:0019260"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002561"},{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0002039"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0002525"}],"interesting_parent_ids":["MONDO:0002561","MONDO:0002039","MONDO:0005066","MONDO:0005559","MONDO:0002525"],"is_obsolete":false,"name":"neuronal ceroid lipofuscinosis 13","secondary_identifiers":["Orphanet:352709","UMLS:C3715049","DOID:0110727","GARD:17527","MEDGEN:811566","OMIM:615362"],"synonyms":[{"name":"CLN13","type":"exact"},{"name":"CLN13 disease","type":"related"},{"name":"CTSF neuronal ceroid lipofuscinosis","type":"exact"},{"name":"ceroid lipofuscinosis, neuronal, 13","type":"related"},{"name":"ceroid lipofuscinosis, neuronal, 13 (Kufs type)","type":"exact"},{"name":"ceroid lipofuscinosis, neuronal, 13, Kufs type","type":"related"},{"name":"ceroid lipofuscinosis, neuronal, type 13","type":"exact"},{"name":"neuronal ceroid lipofuscinosis 13 Kufs type","type":"exact"},{"name":"neuronal ceroid lipofuscinosis caused by mutation in CTSF","type":"exact"},{"name":"neuronal ceroid lipofuscinosis type 13","type":"exact"}],"termid":"MONDO:0014147","xrefs":{"Monarch":{"xref_id":"0014147"}}}


id: GO:0047144
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2-acyl-sn-glycerol 3-phosphate + acyl-CoA = L-phosphatidate + CoA.","definition_xrefs":["GOC:ab","RHEA:14233"],"direct_ancestors":[{"relation_name":"is_a","term_name":"O-acyltransferase activity","termid":"GO:0008374"},{"relation_name":"is_a","term_name":"lysophosphatidic acid acyltransferase activity","termid":"GO:0042171"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016746"}],"interesting_parent_ids":["GO:0016740","GO:0003674","GO:0016746","GO:0003824"],"is_obsolete":false,"name":"2-acylglycerol-3-phosphate O-acyltransferase activity","secondary_identifiers":["Reactome:R-HSA-1482691","Reactome:R-HSA-1482646","EC:2.3.1.52","Reactome:R-HSA-1482533","Reactome:R-HSA-1482546","MetaCyc:2-ACYL2.3.1.15-RXN","Reactome:R-HSA-1482626","Reactome:R-HSA-1482635"],"synonyms":[{"name":"2-acylglycerophosphate acyltransferase activity","type":"related"},{"name":"acyl-CoA:2-acyl-sn-glycerol 3-phosphate O-acyltransferase activity","type":"related"}],"termid":"GO:0047144"}


id: PBO:0077563
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TMEM269 divergent transcript","termid":"PBO:0077563"}


id: GO:0098549
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A stable intercellular bridge between somatic cells. Examples include the intercellular bridges between ovarian follicle cells in insects and between imaginal disc cells in insects.","definition_xrefs":["PMID:670316","GOC:dos","PMID:22135360"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intercellular bridge","termid":"GO:0045171"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"somatic ring canal","termid":"GO:0098549"}


id: GO:0006266
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.","definition_xrefs":["ISBN:0815316194"],"gene_count":0,"genotype_count":0,"name":"obsolete DNA ligation (obsolete GO:0006266)","termid":"GO:0006266"}


id: MONDO:0018226
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Infantile epileptic-dyskinetic encephalopathy is a monogenic disease with epilepsy characterized by developmental delay and infantile spasms in the first months of life, followed by chorea and generalized dystonia and progressing to quadriplegic dyskinesia, recurrent status dystonicus, intractable focal epilepsy and severe intellectual disability.","definition_xrefs":["Orphanet:364063"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete ARX-related epileptic encephalopathy (obsolete MONDO:0015921)","termid":"MONDO:0015921"},{"relation_name":"is_a","term_name":"combined dystonia","termid":"MONDO:0020065"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0003441"}],"interesting_parent_ids":["MONDO:0003441"],"is_obsolete":false,"name":"infantile epileptic-dyskinetic encephalopathy","secondary_identifiers":["MEDGEN:1637882","UMLS:C4552072","GARD:17582","MESH:C567924"],"termid":"MONDO:0018226","xrefs":{"Monarch":{"xref_id":"0018226"}}}


id: GO:0062029
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that starts or increases the rate, frequency or extent of stress-granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.","definition_xrefs":["PMID:20180778"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of stress granule assembly","termid":"GO:0062028"},{"relation_name":"is_a","term_name":"positive regulation of organelle assembly","termid":"GO:1902117"},{"relation_name":"positively_regulates","term_name":"stress granule assembly","termid":"GO:0034063"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044085"},{"rel_name":"positively_regulates","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0008150","GO:0044085"],"is_obsolete":false,"name":"positive regulation of stress granule assembly","termid":"GO:0062029"}


id: GO:0021624
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.","definition_xrefs":["ISBN:0838580343","GOC:dgh","GO_REF:0000021","GOC:cls","GOC:jid","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cranial nerve structural organization","termid":"GO:0021604"},{"relation_name":"part_of","term_name":"oculomotor nerve morphogenesis","termid":"GO:0021622"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"oculomotor nerve structural organization","synonyms":[{"name":"CN III structural organization","type":"related"},{"name":"oculomotor nerve structural organisation","type":"exact"}],"termid":"GO:0021624"}


id: MONDO:1012620
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Inherited disorder of neuromuscular transmission resulting in muscle weakness and fatigability exacerbated by exercise that occurs in dogs due to a mutation in the CHRNE gene.","definition_xrefs":["PMID:38853290"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease, non-human animal","termid":"MONDO:1011321"},{"relation_name":"is_a","term_name":"myasthenia, dog","termid":"MONDO:1012175"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"congenital myasthenic syndrome, CHRNE-related, dog","secondary_identifiers":["OMIA:000685-9615"],"termid":"MONDO:1012620","xrefs":{"Monarch":{"xref_id":"1012620"}}}


id: MONDO:0006921
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Infections with bacteria of the order actinomycetales.","definition_xrefs":["MESH:D000193"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gram-positive bacterial infections","termid":"MONDO:0021679"},{"relation_name":"is_a","term_name":"anaerobic bacteria infectious disease","termid":"MONDO:0024389"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Actinomycetales infectious disease","secondary_identifiers":["SCTID:721751007","MEDGEN:1732","SCTID:11817007","ICD9:039.9","UMLS:C0001255","NCIT:C84534","ICD9:039.8","EFO:1001122"],"synonyms":[{"name":"actinomycetales caused disease or disorder","type":"exact"},{"name":"actinomycetales disease or disorder","type":"exact"},{"name":"actinomycetales infection","type":"exact"},{"name":"actinomycetales infections","type":"exact"},{"name":"actinomycete infection","type":"exact"},{"name":"actinomycete infections","type":"exact"},{"name":"actinomycosis","type":"related"},{"name":"actinomycotic infection","type":"exact"},{"name":"actinomycotic infectious disease","type":"exact"},{"name":"infection caused by actinomycetales","type":"related"},{"name":"infection, actinomycetales","type":"exact"},{"name":"infection, actinomycete","type":"exact"},{"name":"infections, actinomycetales","type":"exact"},{"name":"infections, actinomycete","type":"exact"}],"termid":"MONDO:0006921","xrefs":{"Monarch":{"xref_id":"0006921"}}}


id: FYPO:0002106
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell morphology phenotype in which a vegetatively growing cell is viable, but the cell diameter is larger than normal and the cell length is shorter than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"has_part","term_name":"stubby vegetative cell","termid":"FYPO:0000024"},{"relation_name":"is_a","term_name":"stubby vegetative cell","termid":"FYPO:0000024"},{"relation_name":"is_a","term_name":"viable vegetative cell with abnormal cell shape","termid":"FYPO:0002197"},{"relation_name":"is_a","term_name":"viable vegetative cell with increased cell diameter","termid":"FYPO:0006616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000004"},{"rel_name":"has_part","termid":"FYPO:0000004"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"has_part","termid":"FYPO:0001320"},{"rel_name":"has_part","termid":"FYPO:0000005"},{"rel_name":"is_a","termid":"FYPO:0000005"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000002","FYPO:0000005","FYPO:0001985","FYPO:0000004"],"is_obsolete":false,"name":"viable stubby vegetative cell","synonyms":[{"name":"stubby viable cell during vegetative growth","type":"exact"},{"name":"stubby viable vegetative cell","type":"exact"},{"name":"viable stubby vegetative cell during mitotic cell cycle","type":"related"},{"name":"viable watermelon-shaped vegetative cell","type":"exact"}],"termid":"FYPO:0002106"}


id: PBO:0089834
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial ribosomal protein subunit L33","termid":"PBO:0089834"}


id: PBO:0076491
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TCF21 antisense RNA inducing promoter demethylation","termid":"PBO:0076491"}


id: PR:Q9UT07
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A PRELI domain-containing protein 1, mitochondrial that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO02214","PANTHER:PTHR11158:SF16"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein ups1 homolog (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAP8A3.10","secondary_identifiers":["UniProtKB:Q9UT07"],"synonyms":[{"name":"Spom972h-PRELID1","type":"exact"}],"termid":"PR:Q9UT07"}


id: PBO:0028559
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_protein_localization_to_microtubule_cytoskeleton_during_mitotic_interphase","termid":"PBO:0028559"}


id: GO:0090246
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The morphogenetic process in which a presomitic mesoderm narrows along the left-right axis and lengthens in the rostral-caudal axis contributing to somitogenesis.","definition_xrefs":["GOC:dph","GOC:ascb_2009","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"convergent extension involved in gastrulation","termid":"GO:0060027"},{"relation_name":"is_a","term_name":"convergent extension involved in axis elongation","termid":"GO:0060028"},{"relation_name":"part_of","term_name":"axis elongation involved in somitogenesis","termid":"GO:0090245"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"convergent extension involved in somitogenesis","termid":"GO:0090246"}


id: MONDO:1010508
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Cerebral amyloid angiopathy that occurs in dog.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cerebral amyloid angiopathy, non-human animal","termid":"MONDO:1010028"},{"relation_name":"is_a","term_name":"amyloidosis, dog","termid":"MONDO:1011467"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cerebral amyloid angiopathy, dog","secondary_identifiers":["OMIA:002138-9615"],"termid":"MONDO:1010508","xrefs":{"Monarch":{"xref_id":"1010508"}}}


id: PBO:0051779
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"IQ motif containing B2 pseudogene","termid":"PBO:0051779"}


id: GO:0007437
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of the adult salivary gland are generated and organized.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"salivary gland morphogenesis","termid":"GO:0007435"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"adult salivary gland morphogenesis","termid":"GO:0007437"}


id: MONDO:0003266
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A group of neoplasms which arise from the ependymal lining of the cerebral ventricles and from the remnants of the central canal of the spinal cord. Ependymal tumors occur predominantly in children and young adults with varied morphological features and biological behavior. There are 4 types: ependymoma, anaplastic ependymoma, myxopapillary ependymoma and subependymoma. (WHO)","definition_xrefs":["NCIT:C6770"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glioma","termid":"MONDO:0021042"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ependymal tumor","secondary_identifiers":["GARD:16527","EFO:1000027","ONCOTREE:EPMT","UMLS:C1333407","MEDGEN:232459","Orphanet:301"],"synonyms":[{"name":"ependymal neoplasm","type":"exact"},{"name":"ependymal tumor","type":"exact"},{"name":"ependymal tumors","type":"exact"},{"name":"ependymal tumours","type":"exact"},{"name":"ependymomal tumor","type":"related"},{"name":"ependymomal tumour","type":"related"}],"termid":"MONDO:0003266","xrefs":{"Monarch":{"xref_id":"0003266"}}}


id: PBO:0030533
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_GTPase_activity","termid":"PBO:0030533"}


id: RO:0002638
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"A sub-relation of endoparasite-of in which the parasite inhabits the spaces between host cells.","direct_ancestors":[{"relation_name":"is_a","term_name":"endoparasite_of","termid":"RO:0002634"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"intercellular_endoparasite_of","termid":"RO:0002638"}


id: SO:0000340
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"Structural unit composed of a nucleic acid molecule which controls its own replication through the interaction of specific proteins at one or more origins of replication.","definition_xrefs":["SO:ma"],"direct_ancestors":[{"relation_name":"is_a","term_name":"replicon","termid":"SO:0001235"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome","secondary_identifiers":["http://en.wikipedia.org/wiki/Chromosome"],"termid":"SO:0000340"}


id: PBO:0063310
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PCGF3 antisense RNA 1","termid":"PBO:0063310"}


id: PBO:0081333
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 133","termid":"PBO:0081333"}


id: PR:O14299
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- wis4 gene.","definition_xrefs":["UniProtKB:O14299","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MAP kinase kinase kinase wis4 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC9G1.02","synonyms":[{"name":"MAP kinase kinase kinase wak1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"MAP kinase kinase kinase wik1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-wis4","type":"exact"}],"termid":"PR:O14299"}


id: PBO:0000051
data:
  {"annotation_feature_type":"gene","cv_name":"gene_ex","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcriptionally repressed by Rik1","termid":"PBO:0000051"}


id: PBO:0005394
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"inositol 1,3,4,5,6-pentakisphosphate (IP5) kinase","termid":"PBO:0005394"}


id: GO:0042799
data:
  {"annotated_genes":["SJAG_01146"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[118882],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140943"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: S-adenosyl-L-methionine + histone H4 L-lysine (position 20) = S-adenosyl-L-homocysteine + histone H4 N6-methyl-L-lysine (position 20). This reaction is the addition of a methyl group to the lysine residue at position 20 of the histone H4 protein.","definition_xrefs":["PMID:12086618"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-lysine N-methyltransferase activity","termid":"GO:0016279"},{"relation_name":"is_a","term_name":"histone H4 methyltransferase activity","termid":"GO:0140939"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01146":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0008276"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0140096"}],"interesting_parent_ids":["GO:0003674","GO:0140096","GO:0016740","GO:0003824","GO:0008276","GO:0016741"],"is_obsolete":false,"name":"histone H4K20 methyltransferase activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-2301205","Reactome:R-HSA-5682965"],"synonyms":[{"name":"histone H4 lysine 20-specific methyltransferase activity","type":"exact"},{"name":"histone H4K20 methylase activity","type":"broad"},{"name":"histone H4K20 methylation","type":"exact"},{"name":"histone lysine N-methyltransferase activity (H4-K20 specific)","type":"exact"},{"name":"histone methylase activity (H4-K20 specific)","type":"exact"},{"name":"histone methyltransferase activity (H4-K20 specific)","type":"exact"},{"name":"histone-H4K20 methyltransferase activity","type":"exact"}],"termid":"GO:0042799","terms_by_termid":{"GO:0140943":null}}


id: MONDO:0032736
data:
  {"annotated_genes":["SJAG_03334"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88926],"is_not":false,"summary":null,"term":"MONDO:0032736"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03334":null},"genotype_count":0,"is_obsolete":false,"name":"metabolic crises, recurrent, with variable encephalomyopathic features and neurologic regression","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:618416","MEDGEN:1681269","UMLS:C5193083"],"synonyms":[{"name":"MECREN","type":"related"},{"name":"METABOLIC CRISES, RECURRENT, WITH VARIABLE ENCEPHALOMYOPATHIC FEATURES AND NEUROLOGIC REGRESSION","type":"related"}],"termid":"MONDO:0032736","terms_by_termid":{"MONDO:0032736":null},"xrefs":{"Monarch":{"xref_id":"0032736"}}}


id: MONDO:0013051
data:
  {"annotated_genes":["SJAG_00120"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86946],"is_not":false,"summary":null,"term":"MONDO:0013051"}]},"cv_name":"mondo","definition":"Autosomal recessive cutis laxa type 2B is a rare, hereditary, developmental defect with connective tissue involvement characterized by cutis laxa of variable severity, in utero growth restriction, congenital hip dislocation and joint hyperlaxity, wrinkling of the skin, in particular the dorsum of hands and feet, and progeroid facial features. Hypotonia, developmental delay, and intellectual disability are common. In addition, cataracts, corneal clouding, wormian bones, lipodystrophy and osteopenia have been reported.","definition_xrefs":["Orphanet:357064"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive cutis laxa type 2","termid":"MONDO:0019573"},{"relation_name":"is_a","term_name":"osteogenesis imperfecta and a reduction of bone mineral density.","termid":"MONDO:0800064"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00120":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004736"},{"rel_name":"is_a","termid":"MONDO:0005497"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0005497","MONDO:0006025","MONDO:0004736"],"is_obsolete":false,"name":"autosomal recessive cutis laxa type 2B","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["DOID:0070137","GARD:1641","UMLS:C2751987","MESH:C567855","OMIM:612940","MEDGEN:414526"],"synonyms":[{"name":"ARCL2, progeroid type","type":"exact"},{"name":"ARCL2B","type":"exact"},{"name":"PYCR1 autosomal recessive cutis laxa type 2","type":"exact"},{"name":"autosomal recessive cutis laxa type 2 caused by mutation in PYCR1","type":"exact"},{"name":"autosomal recessive cutis laxa type 2, progeroid type","type":"exact"},{"name":"autosomal recessive cutis laxa type 2B","type":"exact"},{"name":"autosomal recessive cutis laxa type IIB","type":"related"},{"name":"cutis laxa with progeroid features","type":"related"},{"name":"cutis laxa, autosomal recessive type 2B","type":"related"},{"name":"cutis laxa, autosomal recessive, type 2B","type":"related"},{"name":"cutis laxa, autosomal recessive, type IIB","type":"related"}],"termid":"MONDO:0013051","terms_by_termid":{"MONDO:0013051":null},"xrefs":{"Monarch":{"xref_id":"0013051"}}}


id: PBO:0116829
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3-demethoxyubiquinone 3-hydroxylase (NADH) Coq7","termid":"PBO:0116829"}


id: GO:0018577
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: catechol + O2 = 2-hydroxymuconate semialdehyde.","definition_xrefs":["RHEA:17337"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen","termid":"GO:0016702"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"catechol 2,3-dioxygenase activity","secondary_identifiers":["UM-BBD_enzymeID:r0307","EC:1.13.11.2","MetaCyc:CATECHOL-23-DIOXYGENASE-RXN"],"synonyms":[{"name":"2,3-pyrocatechase activity","type":"related"},{"name":"catechol 2,3-oxygenase","type":"related"},{"name":"catechol oxygenase","type":"related"},{"name":"catechol:oxygen 2,3-oxidoreductase (decyclizing)","type":"related"},{"name":"cato2ase activity","type":"related"},{"name":"metapyrocatechase activity","type":"related"},{"name":"pyrocatechol 2,3-dioxygenase","type":"related"}],"termid":"GO:0018577"}


id: MONDO:0005320
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Traumatic or pathological injury to the tibia in which the continuity of the bone is broken.","definition_xrefs":["EFO:0003944"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bone fracture","termid":"MONDO:0005315"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tibia fracture","secondary_identifiers":["SCTID:31978002","MESH:D013978"],"synonyms":[{"name":"bone fracture of tibia","type":"exact"},{"name":"tibia bone fracture","type":"exact"}],"termid":"MONDO:0005320","xrefs":{"Monarch":{"xref_id":"0005320"}}}


id: PBO:0031790
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_cell_fusion_during_conjugation","termid":"PBO:0031790"}


id: PATO:0000600
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A width which is relatively large.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"increased_in_magnitude_relative_to","term_name":"normal","termid":"PATO:0000461"},{"relation_name":"is_a","term_name":"increased size","termid":"PATO:0000586"},{"relation_name":"is_a","term_name":"width","termid":"PATO:0000921"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"increased width","synonyms":[{"name":"broad","type":"related"},{"name":"wide","type":"related"},{"name":"wide/broad","type":"related"}],"termid":"PATO:0000600"}


id: PR:Q9UT61
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An alpha-mannosidase 2C1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO01225","PANTHER:PTHR11607:SF2","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"alpha-mannosidase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC513.05","secondary_identifiers":["UniProtKB:Q9UT61"],"synonyms":[{"name":"Spom972h-MAN2C1","type":"exact"},{"name":"alpha-D-mannoside mannohydrolase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9UT61"}


id: GO:0051280
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of release of sequestered calcium ion into cytosol","termid":"GO:0051279"},{"relation_name":"is_a","term_name":"positive regulation of sequestering of calcium ion","termid":"GO:0051284"},{"relation_name":"is_a","term_name":"negative regulation of calcium ion transmembrane transport","termid":"GO:1903170"},{"relation_name":"negatively_regulates","term_name":"release of sequestered calcium ion into cytosol","termid":"GO:0051209"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"negatively_regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0055085"},{"rel_name":"negatively_regulates","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0055085","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"negative regulation of release of sequestered calcium ion into cytosol","synonyms":[{"name":"down regulation of release of sequestered calcium ion into cytosol","type":"exact"},{"name":"down-regulation of release of sequestered calcium ion into cytosol","type":"exact"},{"name":"downregulation of release of sequestered calcium ion into cytosol","type":"exact"},{"name":"inhibition of release of sequestered calcium ion into cytosol","type":"narrow"},{"name":"negative regulation of calcium ion (Ca2+) mobilization","type":"broad"},{"name":"negative regulation of calcium mobilization","type":"broad"},{"name":"negative regulation of cytoplasmic release of sequestered calcium ion (Ca2+)","type":"broad"},{"name":"negative regulation of cytoplasmic release of stored calcium ion (Ca2+)","type":"broad"},{"name":"negative regulation of cytosolic release of sequestered calcium ion (Ca2+)","type":"exact"},{"name":"negative regulation of cytosolic release of stored calcium ion (Ca2+)","type":"exact"},{"name":"negative regulation of release of sequestered calcium ion (Ca2+)","type":"broad"},{"name":"negative regulation of release of sequestered calcium ion into cytoplasm","type":"broad"},{"name":"negative regulation of release of stored calcium ion (Ca2+)","type":"broad"},{"name":"negative regulation of release of stored calcium ion (Ca2+) into cytoplasm","type":"broad"},{"name":"negative regulation of release of stored calcium ion (Ca2+) into cytosol","type":"exact"}],"termid":"GO:0051280"}


id: PBO:0086177
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein required for the nuclear import and biogenesis of RNA pol II; conflicting evidence on whether null mutant is viable with elongated buds, or inviable; interacts with Rpb2, Rpb3, Nup116p, Nup100p and components of the R2TP complex (Rvb1p, Rvb2p, Pih1p); similar to human TMCO7 gene","termid":"PBO:0086177"}


id: PBO:0014248
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitotic spindle checkpoint ubiquitin ligase Dma1","termid":"PBO:0014248"}


id: MONDO:0015989
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete congenital valvular dysplasia (obsolete MONDO:0015989)","termid":"MONDO:0015989","xrefs":{"Monarch":{"xref_id":"0015989"}}}


id: PBO:0002706
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"actin depolymerizing factor, cofilin","termid":"PBO:0002706"}


id: GO:0005484
data:
  {"annotated_genes":["SJAG_00171","SJAG_03347","SJAG_04023","SJAG_03536","SJAG_02204","SJAG_00804","SJAG_02241","SJAG_03552","SJAG_00899","SJAG_01324","SJAG_04513","SJAG_04978","SJAG_04701","SJAG_03848","SJAG_02103","SJAG_00826","SJAG_04739","SJAG_02586","SJAG_00557"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[61138,70546,73707,74623,75630,77848,77907,78330,79585,79737,92384,95708,98121,99910,101331,111502,114545,119419,120506],"is_not":false,"summary":null,"term":"GO:0005484"}]},"cv_name":"molecular_function","definition":"Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion.","definition_xrefs":["PMID:14570579","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-macromolecule adaptor activity","termid":"GO:0030674"}],"gene_count":19,"genes_by_uniquename":{"SJAG_00171":null,"SJAG_00557":null,"SJAG_00804":null,"SJAG_00826":null,"SJAG_00899":null,"SJAG_01324":null,"SJAG_02103":null,"SJAG_02204":null,"SJAG_02241":null,"SJAG_02586":null,"SJAG_03347":null,"SJAG_03536":null,"SJAG_03552":null,"SJAG_03848":null,"SJAG_04023":null,"SJAG_04513":null,"SJAG_04701":null,"SJAG_04739":null,"SJAG_04978":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0060090"},{"rel_name":"is_a","termid":"GO:0030674"}],"interesting_parent_ids":["GO:0030674","GO:0003674","GO:0060090"],"is_obsolete":false,"name":"SNAP receptor activity","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["GO:0005486","GO:0005485"],"synonyms":[{"name":"Q-SNARE activity","type":"narrow"},{"name":"R-SNARE activity","type":"narrow"},{"name":"SNAP-25","type":"narrow"},{"name":"SNARE","type":"exact"},{"name":"t-SNARE activity","type":"narrow"},{"name":"v-SNARE activity","type":"narrow"}],"termid":"GO:0005484","terms_by_termid":{"GO:0005484":null}}


id: PBO:0047120
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 166 member C","termid":"PBO:0047120"}


id: GO:1903724
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of centriole elongation.","definition_xrefs":["GO_REF:0000058","GOC:als","PMID:20616062","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of centriole replication","termid":"GO:0046601"},{"relation_name":"is_a","term_name":"regulation of centriole elongation","termid":"GO:1903722"},{"relation_name":"positively_regulates","term_name":"centriole elongation","termid":"GO:0061511"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0044085"},{"rel_name":"regulates","termid":"GO:0007049"},{"rel_name":"regulates","termid":"GO:0007010"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0007010"},{"rel_name":"positively_regulates","termid":"GO:0044085"},{"rel_name":"positively_regulates","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0044085","GO:0007010","GO:0007049","GO:0008150"],"is_obsolete":false,"name":"positive regulation of centriole elongation","synonyms":[{"name":"activation of centriole elongation","type":"narrow"},{"name":"up regulation of centriole elongation","type":"exact"},{"name":"up-regulation of centriole elongation","type":"exact"},{"name":"upregulation of centriole elongation","type":"exact"}],"termid":"GO:1903724"}


id: PBO:0027093
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_rDNA_copy_number","termid":"PBO:0027093"}


id: PBO:0082647
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of serine palmitoyltransferase; responsible along with Lcb1p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine","termid":"PBO:0082647"}


id: PBO:0035850
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_histone_H3-K9_dimethylation_at_rDNA_during_vegetative_growth","termid":"PBO:0035850"}


id: MONDO:0007637
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any Fuchs' endothelial dystrophy in which the cause of the disease is a mutation in the COL8A2 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Fuchs' endothelial dystrophy","termid":"MONDO:0005321"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"corneal dystrophy, Fuchs endothelial, 1","secondary_identifiers":["GARD:18216","MESH:C535478","OMIM:136800","MEDGEN:338172","UMLS:C1850959"],"synonyms":[{"name":"COL8A2 Fuchs' endothelial dystrophy","type":"exact"},{"name":"FECD1","type":"related"},{"name":"Fuchs' endothelial dystrophy caused by mutation in COL8A2","type":"exact"},{"name":"corneal dystrophy, Fuchs endothelial, 1","type":"exact"},{"name":"corneal dystrophy, Fuchs endothelial, early-onset","type":"related"},{"name":"corneal dystrophy, Fuchs endothelial, type 1","type":"exact"}],"termid":"MONDO:0007637","xrefs":{"Monarch":{"xref_id":"0007637"}}}


id: MONDO:0002796
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare malignant embryonal neoplasm characterized by the presence of small cells which resemble the cells of classic medulloblastoma and a minor population of melanin-forming neuroepithelial cells. It usually has an unfavorable clinical course.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"medulloblastoma","termid":"MONDO:0007959"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"melanotic medulloblastoma","secondary_identifiers":["ONCOTREE:MMBL","NCIT:C9497","UMLS:C1275668","DOID:3868","MEDGEN:224818"],"synonyms":[{"name":"MMBL","type":"related"},{"name":"medulloblastoma with melanotic differentiation","type":"exact"},{"name":"medulloblastoma, melanotic","type":"exact"},{"name":"medulloblastoma, melanotic (morphologic abnormality)","type":"exact"},{"name":"melanocytic medulloblastoma","type":"exact"},{"name":"melanotic medulloblastoma","type":"exact"}],"termid":"MONDO:0002796","xrefs":{"Monarch":{"xref_id":"0002796"}}}


id: MOD:01387
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-threonine residue to O-methyl-L-threonine.","definition_xrefs":["PubMed:7328054","RESID:AA0464"],"direct_ancestors":[{"relation_name":"is_a","term_name":"O-methylated threonine","termid":"MOD:01803"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00427"}],"interesting_parent_ids":["MOD:00427"],"is_obsolete":false,"name":"O-methyl-L-threonine","synonyms":[{"name":"(2S,3R)-2-amino-3-methoxybutanoic acid","type":"exact"},{"name":"MOD_RES O-methylthreonine","type":"exact"},{"name":"O-methyl threonine","type":"exact"},{"name":"O-methyl-L-threonine","type":"exact"},{"name":"OMeThr","type":"exact"},{"name":"threonine methyl ether","type":"exact"}],"termid":"MOD:01387"}


id: PBO:0017039
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial endonuclease, possibly DNA damage related (predicted)","termid":"PBO:0017039"}


id: PBO:0054925
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2339","termid":"PBO:0054925"}


id: PBO:0052902
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"keratin associated protein 10-13, pseudogene","termid":"PBO:0052902"}


id: MONDO:0800502
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A group of conditions characterized by age-dependent occurrence in otherwise normal children. Cognition and neurological evaluation are typically normal. Remission occurs in almost all patients by puberty. Presumed genetic factors have an important role. Seizure semiology and electroencephalographic (EEG) features are specific for each of the syndromes included in this group.","definition_xrefs":["PMID:35503717"],"direct_ancestors":[{"relation_name":"is_a","term_name":"focal epilepsy","termid":"MONDO:0005384"},{"relation_name":"is_a","term_name":"childhood-onset epilepsy syndrome","termid":"MONDO:0020072"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027"],"is_obsolete":false,"name":"childhood-onset self-limited focal epilepsy syndrome","synonyms":[{"name":"childhood-onset SeLFE","type":"exact"}],"termid":"MONDO:0800502","xrefs":{"Monarch":{"xref_id":"0800502"}}}


id: PBO:0070801
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L12 pseudogene 31","termid":"PBO:0070801"}


id: PBO:0066775
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RN7SK pseudogene 73","termid":"PBO:0066775"}


id: PBO:0058425
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4795","termid":"PBO:0058425"}


id: GO:0035492
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response.","definition_xrefs":["GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of leukotriene production involved in inflammatory response","termid":"GO:0035490"},{"relation_name":"is_a","term_name":"negative regulation of inflammatory response","termid":"GO:0050728"},{"relation_name":"is_a","term_name":"negative regulation of multicellular organismal process","termid":"GO:0051241"},{"relation_name":"negatively_regulates","term_name":"leukotriene production involved in inflammatory response","termid":"GO:0002540"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of leukotriene production involved in inflammatory response","termid":"GO:0035492"}


id: PBO:0090911
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"plasma membrane NiCoT heavy metal ion transmembrane transporter Nic1","termid":"PBO:0090911"}


id: PBO:0064002
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"piwi-interacting RNA cluster 36","termid":"PBO:0064002"}


id: MONDO:0005043
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An abnormal increase in the number of cells in an organ or a tissue with consequent enlargement.","definition_xrefs":["NCIT:C3113"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cancer or benign tumor","termid":"MONDO:0045024"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hyperplasia","secondary_identifiers":["MESH:D006965","UMLS:C0020507","EFO:0000536","MEDGEN:43784"],"synonyms":[{"name":"hyperplasia","type":"exact"},{"name":"hyperplastic","type":"exact"}],"termid":"MONDO:0005043","xrefs":{"Monarch":{"xref_id":"0005043"}}}


id: GO:0090444
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and the rate at which this time point is reached.","definition_xrefs":["PMID:17550772"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of development, heterochronic","termid":"GO:0040034"},{"relation_name":"is_a","term_name":"regulation of nematode larval development","termid":"GO:0061062"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of nematode larval development, heterochronic","termid":"GO:0090444"}


id: GO:0103050
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: isobutanol + NADP = isobutyraldehyde + NADPH + H+.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete isobutyraldehyde reductase activity (obsolete GO:0103050)","termid":"GO:0103050"}


id: MONDO:1011892
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"nervous system disorder, non-human animal","termid":"MONDO:1011336"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spinal intradural arachnoid cyst, non-human animal","secondary_identifiers":["OMIA:001923"],"termid":"MONDO:1011892","xrefs":{"Monarch":{"xref_id":"1011892"}}}


id: GO:1904747
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development.","definition_xrefs":["GO_REF:0000058","GOC:TermGenie","PMID:22801495"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of apoptotic process","termid":"GO:0043065"},{"relation_name":"is_a","term_name":"positive regulation of developmental process","termid":"GO:0051094"},{"relation_name":"is_a","term_name":"regulation of apoptotic process involved in development","termid":"GO:1904748"},{"relation_name":"positively_regulates","term_name":"apoptotic process involved in development","termid":"GO:1902742"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of apoptotic process involved in development","synonyms":[{"name":"activation of activation of apoptosis involved in anatomical structure development","type":"narrow"},{"name":"activation of activation of apoptosis involved in development of an anatomical structure","type":"narrow"},{"name":"activation of apoptosis activator activity involved in anatomical structure development","type":"related"},{"name":"activation of apoptosis activator activity involved in development of an anatomical structure","type":"related"},{"name":"activation of apoptosis involved in anatomical structure development","type":"narrow"},{"name":"activation of apoptosis involved in development of an anatomical structure","type":"narrow"},{"name":"activation of apoptosis signaling involved in anatomical structure development","type":"narrow"},{"name":"activation of apoptosis signaling involved in development of an anatomical structure","type":"narrow"},{"name":"activation of apoptotic cell death involved in anatomical structure development","type":"narrow"},{"name":"activation of apoptotic cell death involved in development of an anatomical structure","type":"narrow"},{"name":"activation of apoptotic process involved in anatomical structure development","type":"narrow"},{"name":"activation of apoptotic process involved in development","type":"narrow"},{"name":"activation of apoptotic process involved in development of an anatomical structure","type":"narrow"},{"name":"activation of apoptotic program involved in anatomical structure development","type":"narrow"},{"name":"activation of apoptotic program involved in development of an anatomical structure","type":"narrow"},{"name":"activation of apoptotic programmed cell death involved in anatomical structure development","type":"narrow"},{"name":"activation of apoptotic programmed cell death involved in development of an anatomical structure","type":"narrow"},{"name":"activation of commitment to apoptosis involved in anatomical structure development","type":"related"},{"name":"activation of commitment to apoptosis involved in development of an anatomical structure","type":"related"},{"name":"activation of induction of apoptosis by p53 involved in anatomical structure development","type":"related"},{"name":"activation of induction of apoptosis by p53 involved in development of an anatomical structure","type":"related"},{"name":"activation of induction of apoptosis involved in anatomical structure development","type":"related"},{"name":"activation of induction of apoptosis involved in development of an anatomical structure","type":"related"},{"name":"activation of programmed cell death by apoptosis involved in anatomical structure development","type":"narrow"},{"name":"activation of programmed cell death by apoptosis involved in development of an anatomical structure","type":"narrow"},{"name":"activation of signaling (initiator) caspase activity involved in anatomical structure development","type":"related"},{"name":"activation of signaling (initiator) caspase activity involved in development of an anatomical structure","type":"related"},{"name":"activation of type I programmed cell death involved in anatomical structure development","type":"narrow"},{"name":"activation of type I programmed cell death involved in development of an anatomical structure","type":"narrow"},{"name":"positive regulation of activation of apoptosis involved in anatomical structure development","type":"narrow"},{"name":"positive regulation of activation of apoptosis involved in development of an anatomical structure","type":"narrow"},{"name":"positive regulation of apoptosis activator activity involved in anatomical structure development","type":"related"},{"name":"positive regulation of apoptosis activator activity involved in development of an anatomical structure","type":"related"},{"name":"positive regulation of apoptosis involved in anatomical structure development","type":"narrow"},{"name":"positive regulation of apoptosis involved in development of an anatomical structure","type":"narrow"},{"name":"positive regulation of apoptosis signaling involved in anatomical structure development","type":"narrow"},{"name":"positive regulation of apoptosis signaling involved in development of an anatomical structure","type":"narrow"},{"name":"positive regulation of apoptotic cell death involved in anatomical structure development","type":"exact"},{"name":"positive regulation of apoptotic cell death involved in development of an anatomical structure","type":"exact"},{"name":"positive regulation of apoptotic process involved in anatomical structure development","type":"exact"},{"name":"positive regulation of apoptotic process involved in development of an anatomical structure","type":"exact"},{"name":"positive regulation of apoptotic program involved in anatomical structure development","type":"narrow"},{"name":"positive regulation of apoptotic program involved in development of an anatomical structure","type":"narrow"},{"name":"positive regulation of apoptotic programmed cell death involved in anatomical structure development","type":"exact"},{"name":"positive regulation of apoptotic programmed cell death involved in development of an anatomical structure","type":"exact"},{"name":"positive regulation of commitment to apoptosis involved in anatomical structure development","type":"related"},{"name":"positive regulation of commitment to apoptosis involved in development of an anatomical structure","type":"related"},{"name":"positive regulation of induction of apoptosis by p53 involved in anatomical structure development","type":"related"},{"name":"positive regulation of induction of apoptosis by p53 involved in development of an anatomical structure","type":"related"},{"name":"positive regulation of induction of apoptosis involved in anatomical structure development","type":"related"},{"name":"positive regulation of induction of apoptosis involved in development of an anatomical structure","type":"related"},{"name":"positive regulation of programmed cell death by apoptosis involved in anatomical structure development","type":"exact"},{"name":"positive regulation of programmed cell death by apoptosis involved in development of an anatomical structure","type":"exact"},{"name":"positive regulation of signaling (initiator) caspase activity involved in anatomical structure development","type":"related"},{"name":"positive regulation of signaling (initiator) caspase activity involved in development of an anatomical structure","type":"related"},{"name":"positive regulation of type I programmed cell death involved in anatomical structure development","type":"narrow"},{"name":"positive regulation of type I programmed cell death involved in development of an anatomical structure","type":"narrow"},{"name":"up regulation of activation of apoptosis involved in anatomical structure development","type":"narrow"},{"name":"up regulation of activation of apoptosis involved in development of an anatomical structure","type":"narrow"},{"name":"up regulation of apoptosis activator activity involved in anatomical structure development","type":"related"},{"name":"up regulation of apoptosis activator activity involved in development of an anatomical structure","type":"related"},{"name":"up regulation of apoptosis involved in anatomical structure development","type":"narrow"},{"name":"up regulation of apoptosis involved in development of an anatomical structure","type":"narrow"},{"name":"up regulation of apoptosis signaling involved in anatomical structure development","type":"narrow"},{"name":"up regulation of apoptosis signaling involved in development of an anatomical structure","type":"narrow"},{"name":"up regulation of apoptotic cell death involved in anatomical structure development","type":"exact"},{"name":"up regulation of apoptotic cell death involved in development of an anatomical structure","type":"exact"},{"name":"up regulation of apoptotic process involved in anatomical structure development","type":"exact"},{"name":"up regulation of apoptotic process involved in development","type":"exact"},{"name":"up regulation of apoptotic process involved in development of an anatomical structure","type":"exact"},{"name":"up regulation of apoptotic program involved in anatomical structure development","type":"narrow"},{"name":"up regulation of apoptotic program involved in development of an anatomical structure","type":"narrow"},{"name":"up regulation of apoptotic programmed cell death involved in anatomical structure development","type":"exact"},{"name":"up regulation of apoptotic programmed cell death involved in development of an anatomical structure","type":"exact"},{"name":"up regulation of commitment to apoptosis involved in anatomical structure development","type":"related"},{"name":"up regulation of commitment to apoptosis involved in development of an anatomical structure","type":"related"},{"name":"up regulation of induction of apoptosis by p53 involved in anatomical structure development","type":"related"},{"name":"up regulation of induction of apoptosis by p53 involved in development of an anatomical structure","type":"related"},{"name":"up regulation of induction of apoptosis involved in anatomical structure development","type":"related"},{"name":"up regulation of induction of apoptosis involved in development of an anatomical structure","type":"related"},{"name":"up regulation of programmed cell death by apoptosis involved in anatomical structure development","type":"exact"},{"name":"up regulation of programmed cell death by apoptosis involved in development of an anatomical structure","type":"exact"},{"name":"up regulation of signaling (initiator) caspase activity involved in anatomical structure development","type":"related"},{"name":"up regulation of signaling (initiator) caspase activity involved in development of an anatomical structure","type":"related"},{"name":"up regulation of type I programmed cell death involved in anatomical structure development","type":"narrow"},{"name":"up regulation of type I programmed cell death involved in development of an anatomical structure","type":"narrow"},{"name":"up-regulation of activation of apoptosis involved in anatomical structure development","type":"narrow"},{"name":"up-regulation of activation of apoptosis involved in development of an anatomical structure","type":"narrow"},{"name":"up-regulation of apoptosis activator activity involved in anatomical structure development","type":"related"},{"name":"up-regulation of apoptosis activator activity involved in development of an anatomical structure","type":"related"},{"name":"up-regulation of apoptosis involved in anatomical structure development","type":"narrow"},{"name":"up-regulation of apoptosis involved in development of an anatomical structure","type":"narrow"},{"name":"up-regulation of apoptosis signaling involved in anatomical structure development","type":"narrow"},{"name":"up-regulation of apoptosis signaling involved in development of an anatomical structure","type":"narrow"},{"name":"up-regulation of apoptotic cell death involved in anatomical structure development","type":"exact"},{"name":"up-regulation of apoptotic cell death involved in development of an anatomical structure","type":"exact"},{"name":"up-regulation of apoptotic process involved in anatomical structure development","type":"exact"},{"name":"up-regulation of apoptotic process involved in development","type":"exact"},{"name":"up-regulation of apoptotic process involved in development of an anatomical structure","type":"exact"},{"name":"up-regulation of apoptotic program involved in anatomical structure development","type":"narrow"},{"name":"up-regulation of apoptotic program involved in development of an anatomical structure","type":"narrow"},{"name":"up-regulation of apoptotic programmed cell death involved in anatomical structure development","type":"exact"},{"name":"up-regulation of apoptotic programmed cell death involved in development of an anatomical structure","type":"exact"},{"name":"up-regulation of commitment to apoptosis involved in anatomical structure development","type":"related"},{"name":"up-regulation of commitment to apoptosis involved in development of an anatomical structure","type":"related"},{"name":"up-regulation of induction of apoptosis by p53 involved in anatomical structure development","type":"related"},{"name":"up-regulation of induction of apoptosis by p53 involved in development of an anatomical structure","type":"related"},{"name":"up-regulation of induction of apoptosis involved in anatomical structure development","type":"related"},{"name":"up-regulation of induction of apoptosis involved in development of an anatomical structure","type":"related"},{"name":"up-regulation of programmed cell death by apoptosis involved in anatomical structure development","type":"exact"},{"name":"up-regulation of programmed cell death by apoptosis involved in development of an anatomical structure","type":"exact"},{"name":"up-regulation of signaling (initiator) caspase activity involved in anatomical structure development","type":"related"},{"name":"up-regulation of signaling (initiator) caspase activity involved in development of an anatomical structure","type":"related"},{"name":"up-regulation of type I programmed cell death involved in anatomical structure development","type":"narrow"},{"name":"up-regulation of type I programmed cell death involved in development of an anatomical structure","type":"narrow"},{"name":"upregulation of activation of apoptosis involved in anatomical structure development","type":"narrow"},{"name":"upregulation of activation of apoptosis involved in development of an anatomical structure","type":"narrow"},{"name":"upregulation of apoptosis activator activity involved in anatomical structure development","type":"related"},{"name":"upregulation of apoptosis activator activity involved in development of an anatomical structure","type":"related"},{"name":"upregulation of apoptosis involved in anatomical structure development","type":"narrow"},{"name":"upregulation of apoptosis involved in development of an anatomical structure","type":"narrow"},{"name":"upregulation of apoptosis signaling involved in anatomical structure development","type":"narrow"},{"name":"upregulation of apoptosis signaling involved in development of an anatomical structure","type":"narrow"},{"name":"upregulation of apoptotic cell death involved in anatomical structure development","type":"exact"},{"name":"upregulation of apoptotic cell death involved in development of an anatomical structure","type":"exact"},{"name":"upregulation of apoptotic process involved in anatomical structure development","type":"exact"},{"name":"upregulation of apoptotic process involved in development","type":"exact"},{"name":"upregulation of apoptotic process involved in development of an anatomical structure","type":"exact"},{"name":"upregulation of apoptotic program involved in anatomical structure development","type":"narrow"},{"name":"upregulation of apoptotic program involved in development of an anatomical structure","type":"narrow"},{"name":"upregulation of apoptotic programmed cell death involved in anatomical structure development","type":"exact"},{"name":"upregulation of apoptotic programmed cell death involved in development of an anatomical structure","type":"exact"},{"name":"upregulation of commitment to apoptosis involved in anatomical structure development","type":"related"},{"name":"upregulation of commitment to apoptosis involved in development of an anatomical structure","type":"related"},{"name":"upregulation of induction of apoptosis by p53 involved in anatomical structure development","type":"related"},{"name":"upregulation of induction of apoptosis by p53 involved in development of an anatomical structure","type":"related"},{"name":"upregulation of induction of apoptosis involved in anatomical structure development","type":"related"},{"name":"upregulation of induction of apoptosis involved in development of an anatomical structure","type":"related"},{"name":"upregulation of programmed cell death by apoptosis involved in anatomical structure development","type":"exact"},{"name":"upregulation of programmed cell death by apoptosis involved in development of an anatomical structure","type":"exact"},{"name":"upregulation of signaling (initiator) caspase activity involved in anatomical structure development","type":"related"},{"name":"upregulation of signaling (initiator) caspase activity involved in development of an anatomical structure","type":"related"},{"name":"upregulation of type I programmed cell death involved in anatomical structure development","type":"narrow"},{"name":"upregulation of type I programmed cell death involved in development of an anatomical structure","type":"narrow"}],"termid":"GO:1904747"}


id: PBO:0005422
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial matrix PGP phosphatase involved in cardiolipin biosynthesis Gep4 (predicted)","termid":"PBO:0005422"}


id: GO:0052167
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a symbiont alters or subverts the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated perturbation of host immune response","termid":"GO:0052553"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"symbiont-mediated perturbation of host innate immune response","secondary_identifiers":["GO:0052306"],"synonyms":[{"name":"modulation by organism of innate immune response in other organism involved in symbiotic interaction","type":"broad"},{"name":"modulation by symbiont of host innate immunity","type":"exact"},{"name":"modulation of host innate immune response","type":"exact"},{"name":"perturbation of host innate immune response","type":"exact"}],"termid":"GO:0052167"}


id: FYPO:0001472
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing tacrolimus during a cellular response to osmotic stress.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal growth during cellular response to osmotic stress","termid":"FYPO:0001021"},{"relation_name":"is_a","term_name":"normal growth on tacrolimus","termid":"FYPO:0001470"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0000139"}],"interesting_parent_ids":["FYPO:0002057","FYPO:0002060","FYPO:0002058","FYPO:0000139","FYPO:0000003","FYPO:0000257"],"is_obsolete":false,"name":"normal growth on tacrolimus during osmotic stress","synonyms":[{"name":"normal cell population growth in presence of tacrolimus during osmotic stress","type":"exact"},{"name":"normal cell population growth on tacrolimus and sorbitol","type":"narrow"},{"name":"normal cell population growth on tacrolimus during osmotic stress","type":"exact"},{"name":"normal cellular response to FK506 during osmotic stress","type":"exact"},{"name":"normal cellular response to tacrolimus and osmotic stress","type":"related"},{"name":"normal cellular response to tacrolimus and sorbitol","type":"related"},{"name":"normal cellular response to tacrolimus during osmotic stress","type":"related"},{"name":"normal vegetative cell population growth on tacrolimus during osmotic stress","type":"exact"}],"termid":"FYPO:0001472"}


id: PBO:0084735
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial intermediate peptidase; cleaves destabilizing N-terminal residues of a subset of proteins upon import, after their cleavage by mitochondrial processing peptidase (Mas1p-Mas2p); may contribute to mitochondrial iron homeostasis","termid":"PBO:0084735"}


id: PBO:0047733
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"formin binding protein 1 pseudogene 2","termid":"PBO:0047733"}


id: PBO:0042526
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cyclin dependent kinase 3","termid":"PBO:0042526"}


id: PBO:0047853
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fragile site, aphidicolin type, common, fra(1)(q21)","termid":"PBO:0047853"}


id: PBO:0055579
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 3015","termid":"PBO:0055579"}


id: PBO:0071477
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L32 pseudogene 18","termid":"PBO:0071477"}


id: PBO:0050991
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"intraflagellar transport 81","termid":"PBO:0050991"}


id: PBO:0044691
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"discoidin domain receptor tyrosine kinase 2","termid":"PBO:0044691"}


id: GO:0051413
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues.","definition_xrefs":["PMID:11276391","ISBN:0721662544"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to glucocorticoid","termid":"GO:0051384"},{"relation_name":"is_a","term_name":"response to alcohol","termid":"GO:0097305"},{"relation_name":"is_a","term_name":"response to ketone","termid":"GO:1901654"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to cortisone","synonyms":[{"name":"response to cortisone stimulus","type":"exact"}],"termid":"GO:0051413"}


id: MONDO:0016855
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Mowat-Wilson syndrome","termid":"MONDO:0009341"},{"relation_name":"is_a","term_name":"partial deletion of the long arm of chromosome 2","termid":"MONDO:0016901"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0005027"},{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320","MONDO:0000426","MONDO:0005027"],"is_obsolete":false,"name":"Mowat-Wilson syndrome due to monosomy 2q22","secondary_identifiers":["Orphanet:261537","UMLS:C5437617","GARD:17248","MEDGEN:1723926"],"synonyms":[{"name":"Hirschsprung disease and intellectual disability due to 2q22 microdeletion","type":"exact"},{"name":"Hirschsprung disease and intellectual disability due to del(2)(q22)","type":"exact"},{"name":"Hirschsprung disease and intellectual disability due to monosomy 2q22","type":"exact"},{"name":"Mowat-Wilson syndrome due to 2q22 microdeletion","type":"exact"},{"name":"Mowat-Wilson syndrome due to del(2)q(22)","type":"exact"},{"name":"Mowat-Wilson syndrome due to monosomy type 2q22","type":"exact"}],"termid":"MONDO:0016855","xrefs":{"Monarch":{"xref_id":"0016855"}}}


id: GO:0033350
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tetrose biosynthetic process","termid":"GO:0033348"},{"relation_name":"is_a","term_name":"apiose metabolic process","termid":"GO:0033349"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0005975","GO:0044281"],"is_obsolete":false,"name":"apiose biosynthetic process","synonyms":[{"name":"apiose anabolism","type":"exact"},{"name":"apiose biosynthesis","type":"exact"},{"name":"apiose formation","type":"exact"},{"name":"apiose synthesis","type":"exact"}],"termid":"GO:0033350"}


id: GO:0035922
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The morphogenetic process in which the foramen ovale closes after birth, to prevent blood flow between the right and left atria. In the fetal heart, the foramen ovale allows blood to enter the left atrium from the right atrium. Closure of the foramen ovale after birth stops this blood flow.","definition_xrefs":["PMID:19762328","GOC:vk","GOC:BHF","UBERON:0004754","Wikipedia:Foramen_ovale_(heart)"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure morphogenesis","termid":"GO:0009653"},{"relation_name":"part_of","term_name":"cardiac septum morphogenesis","termid":"GO:0060411"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"foramen ovale closure","synonyms":[{"name":"foramen ovale of heart closure","type":"exact"}],"termid":"GO:0035922"}


id: PBO:0004464
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GTPase regulator (predicted)","termid":"PBO:0004464"}


id: PBO:0038973
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"adenosine A2b receptor pseudogene 1","termid":"PBO:0038973"}


id: MONDO:0017406
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"congenital hypogonadotropic hypogonadism","termid":"MONDO:0015770"},{"relation_name":"is_a","term_name":"disorder of development or morphogenesis","termid":"MONDO:0021147"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hypogonadotropic hypogonadism-severe microcephaly-sensorineural hearing loss-dysmorphism syndrome","secondary_identifiers":["GARD:21174","MEDGEN:1663043","Orphanet:293967","UMLS:C4751123"],"synonyms":[{"name":"hypogonadotropic hypogonadism-severe microcephaly-sensorineural deafness-dysmorphism syndrome","type":"exact"}],"termid":"MONDO:0017406","xrefs":{"Monarch":{"xref_id":"0017406"}}}


id: PR:O74350
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- bdc1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O74350"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bromodomain-containing protein 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC21D10.10","synonyms":[{"name":"Spom972h-bdc1","type":"exact"}],"termid":"PR:O74350"}


id: GO:0015665
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of an alcohol from one side of a membrane to the other. An alcohol is any carbon compound that contains a hydroxyl group.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transmembrane transporter activity","termid":"GO:0022857"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0005215","GO:0003674","GO:0022857"],"is_obsolete":false,"name":"alcohol transmembrane transporter activity","termid":"GO:0015665"}


id: PBO:0030182
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-viable_vegetative_cell_population","termid":"PBO:0030182"}


id: GO:0035819
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"An increase in the amount of sodium excreted in urine over a unit of time, as a result of pressure natriuresis.","definition_xrefs":["GOC:yaf","GOC:mtg_25march11"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pressure natriuresis","termid":"GO:0003095"},{"relation_name":"is_a","term_name":"positive regulation of renal sodium excretion","termid":"GO:0035815"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0008150"],"is_obsolete":false,"name":"positive regulation of renal sodium excretion by pressure natriuresis","synonyms":[{"name":"natriuresis resulting from pressure natriuresis","type":"related"}],"termid":"GO:0035819"}


id: PBO:0071385
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L30 pseudogene 8","termid":"PBO:0071385"}


id: PBO:0082102
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"AAA-ATPase involved in multivesicular body (MVB) protein sorting; ATP-bound Vps4p localizes to endosomes and catalyzes ESCRT-III disassembly and membrane release; ATPase activity is activated by Vta1p; regulates cellular sterol metabolism","termid":"PBO:0082102"}


id: PBO:0089240
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spindle pole body half bridge protein, centrin Cdc31","termid":"PBO:0089240"}


id: PBO:0085920
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; identical to Pau1p","termid":"PBO:0085920"}


id: MONDO:1011920
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"reproductive system disorder, non-human animal","termid":"MONDO:1011354"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"yellow-semen syndrome, non-human animal","secondary_identifiers":["OMIA:001304"],"termid":"MONDO:1011920","xrefs":{"Monarch":{"xref_id":"1011920"}}}


id: MONDO:0018630
data:
  {"annotated_genes":["SJAG_01620","SJAG_02226","SJAG_02187","SJAG_02748"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88158],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007356"},{"annotations":[86973],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012249"},{"annotations":[87423],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013699"},{"annotations":[87425],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013710"},{"annotations":[87436,87435],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008018"}]},"cv_name":"mondo","definition":"Hereditary nonpolyposis colon cancer (HNPCC) is a cancer-predisposing condition characterized by the development of colorectal cancer not associated with colorectal polyposis, endometrial cancer, and various other cancers (such as malignant epithelial tumor of ovary, gastric, biliary tract, small bowel, and urinary tract cancer) that are frequently diagnosed at an early age.","definition_xrefs":["Orphanet:443909"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary neoplastic syndrome","termid":"MONDO:0015356"},{"relation_name":"is_a","term_name":"familial colorectal cancer","termid":"MONDO:0023113"}],"gene_count":4,"genes_by_uniquename":{"SJAG_01620":null,"SJAG_02187":null,"SJAG_02226":null,"SJAG_02748":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0004335"],"is_obsolete":false,"name":"hereditary nonpolyposis colon cancer","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIMPS:120435","MEDGEN:232602","NCIT:C120083","SCTID:315058005","UMLS:C1333990"],"synonyms":[{"name":"HNPCC","type":"exact"},{"name":"Hereditary nonpolyposis colorectal cancer (HNPCC)","type":"exact"},{"name":"colorectal cancer, hereditary nonpolyposis","type":"exact"},{"name":"familial nonpolyposis colon cancer","type":"exact"},{"name":"familial nonpolyposis colorectal cancer","type":"exact"},{"name":"hereditary nonpolyposis colon cancer","type":"exact"},{"name":"hereditary nonpolyposis colorectal cancer","type":"exact"}],"termid":"MONDO:0018630","terms_by_termid":{"MONDO:0007356":null,"MONDO:0008018":null,"MONDO:0012249":null,"MONDO:0013699":null,"MONDO:0013710":null},"xrefs":{"Monarch":{"xref_id":"0018630"}}}


id: GO:1905451
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis.","definition_xrefs":["PMID:18832707","GO_REF:0000058","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of immune effector process","termid":"GO:0002699"},{"relation_name":"is_a","term_name":"positive regulation of phagocytosis","termid":"GO:0050766"},{"relation_name":"is_a","term_name":"positive regulation of Fc receptor mediated stimulatory signaling pathway","termid":"GO:0060369"},{"relation_name":"is_a","term_name":"regulation of Fc-gamma receptor signaling pathway involved in phagocytosis","termid":"GO:1905449"},{"relation_name":"positively_regulates","term_name":"Fc-gamma receptor signaling pathway involved in phagocytosis","termid":"GO:0038096"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0016192"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"positively_regulates","termid":"GO:0023052"},{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0016192"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0016192","GO:0006810","GO:0023052"],"is_obsolete":false,"name":"positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis","synonyms":[{"name":"activation of Fc gamma receptor-dependent phagocytosis","type":"narrow"},{"name":"activation of Fc-gamma receptor signaling pathway involved in phagocytosis","type":"narrow"},{"name":"activation of Fc-gamma receptor signalling pathway involved in phagocytosis","type":"narrow"},{"name":"activation of Fcgamma receptor-mediated phagocytosis","type":"narrow"},{"name":"activation of IgG-mediated phagocytosis","type":"narrow"},{"name":"positive regulation of Fc gamma receptor-dependent phagocytosis","type":"exact"},{"name":"positive regulation of Fc-gamma receptor signalling pathway involved in phagocytosis","type":"exact"},{"name":"positive regulation of Fcgamma receptor-mediated phagocytosis","type":"exact"},{"name":"positive regulation of IgG-mediated phagocytosis","type":"exact"},{"name":"up regulation of Fc gamma receptor-dependent phagocytosis","type":"exact"},{"name":"up regulation of Fc-gamma receptor signaling pathway involved in phagocytosis","type":"exact"},{"name":"up regulation of Fc-gamma receptor signalling pathway involved in phagocytosis","type":"exact"},{"name":"up regulation of Fcgamma receptor-mediated phagocytosis","type":"exact"},{"name":"up regulation of IgG-mediated phagocytosis","type":"exact"},{"name":"up-regulation of Fc gamma receptor-dependent phagocytosis","type":"exact"},{"name":"up-regulation of Fc-gamma receptor signaling pathway involved in phagocytosis","type":"exact"},{"name":"up-regulation of Fc-gamma receptor signalling pathway involved in phagocytosis","type":"exact"},{"name":"up-regulation of Fcgamma receptor-mediated phagocytosis","type":"exact"},{"name":"up-regulation of IgG-mediated phagocytosis","type":"exact"},{"name":"upregulation of Fc gamma receptor-dependent phagocytosis","type":"exact"},{"name":"upregulation of Fc-gamma receptor signaling pathway involved in phagocytosis","type":"exact"},{"name":"upregulation of Fc-gamma receptor signalling pathway involved in phagocytosis","type":"exact"},{"name":"upregulation of Fcgamma receptor-mediated phagocytosis","type":"exact"},{"name":"upregulation of IgG-mediated phagocytosis","type":"exact"}],"termid":"GO:1905451"}


id: GO:0019626
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of a short-chain fatty acid. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"fatty acid catabolic process","termid":"GO:0009062"},{"relation_name":"is_a","term_name":"short-chain fatty acid metabolic process","termid":"GO:0046459"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0006629"],"is_obsolete":false,"name":"short-chain fatty acid catabolic process","secondary_identifiers":["MetaCyc:ACETOACETATE-DEG-PWY","Reactome:R-HSA-71032"],"synonyms":[{"name":"short-chain fatty acid breakdown","type":"exact"},{"name":"short-chain fatty acid catabolism","type":"exact"},{"name":"short-chain fatty acid degradation","type":"exact"}],"termid":"GO:0019626"}


id: PBO:0044966
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dehydrogenase/reductase 12","termid":"PBO:0044966"}


id: PR:Q9USL3
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An isoleucine--tRNA ligase, mitochondrial that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO04430","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"isoleucine--tRNA ligase, mitochondrial (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC18B5.08c","secondary_identifiers":["UniProtKB:Q9USL3"],"synonyms":[{"name":"IleRS (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-IARS2","type":"exact"},{"name":"isoleucyl-tRNA synthetase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9USL3"}


id: PBO:0048406
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"growth arrest associated lncRNA 1","termid":"PBO:0048406"}


id: FYPO:0007057
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of substances via vesicles from recycling endosomes to the Golgi is abnormal.","definition_xrefs":["GO:0071955","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal vesicle-mediated transport during vegetative growth","termid":"FYPO:0000213"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001320","FYPO:0001985","FYPO:0000138","FYPO:0000002"],"is_obsolete":false,"name":"abnormal recycling endosome to Golgi transport","synonyms":[{"name":"abnormal recycling endosome to Golgi transport during mitotic cell cycle","type":"related"},{"name":"abnormal recycling endosome to Golgi transport during vegetative growth","type":"exact"}],"termid":"FYPO:0007057"}


id: GO:0019386
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other compounds, including carbon dioxide (CO2).","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"methanogenesis","termid":"GO:0015948"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006091"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006091","GO:0008150"],"is_obsolete":false,"name":"methanogenesis, from carbon dioxide","secondary_identifiers":["MetaCyc:METHANOGENESIS-PWY"],"synonyms":[{"name":"methane biosynthesis from carbon dioxide","type":"exact"},{"name":"methane biosynthetic process from carbon dioxide","type":"exact"}],"termid":"GO:0019386"}


id: MONDO:0100317
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any disease or disorder in which the cause of the disease is a mutation in the ADA2 gene.","definition_xrefs":["PMID:32845415","PMID:35774100","PMID:35095905","PMID:32638197","PMID:31945408"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disorder of connective tissue","termid":"MONDO:0023603"},{"relation_name":"is_a","term_name":"type 1 interferonopathy of childhood","termid":"MONDO:0957408"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"deficiency of adenosine deaminase 2","secondary_identifiers":["UMLS:C4289994","MEDGEN:927526"],"termid":"MONDO:0100317","xrefs":{"Monarch":{"xref_id":"0100317"}}}


id: MONDO:0012188
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Neuronal ceroid lipofuscinosis 9 (CLN9-NCL) is a rare condition that affects the nervous system. Signs and symptoms of the condition generally develop in early childhood (average age 4 years) and may include loss of muscle coordination (ataxia), seizures that do not respond to medications, muscle twitches (myoclonus), visual impairment, and developmental regression (the loss of previously acquired skills). The underlying genetic cause of CLN9-NCLis unknown but it appears to be inherited in an autosomal recessive manner. Treatment options are limited to therapies that can help relieve some of the symptoms.","direct_ancestors":[{"relation_name":"is_a","term_name":"juvenile neuronal ceroid lipofuscinosis","termid":"MONDO:0019262"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0002561"},{"rel_name":"is_a","termid":"MONDO:0002039"},{"rel_name":"is_a","termid":"MONDO:0002525"}],"interesting_parent_ids":["MONDO:0005559","MONDO:0002525","MONDO:0005066","MONDO:0002039","MONDO:0002561"],"is_obsolete":false,"name":"neuronal ceroid lipofuscinosis 9","secondary_identifiers":["OMIM:609055","UMLS:C1836841","Orphanet:228357","MEDGEN:332304","DOID:0110733","GARD:6618","MESH:C537953"],"synonyms":[{"name":"CLN 9","type":"related"},{"name":"CLN9","type":"exact"},{"name":"CLN9 disease","type":"related"},{"name":"ceroid lipofuscinosis, neuronal, 9","type":"related"},{"name":"neuronal ceroid lipofuscinosis type 9","type":"exact"}],"termid":"MONDO:0012188","xrefs":{"Monarch":{"xref_id":"0012188"}}}


id: PBO:0011452
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HOPs/CORVET complex subunit Vps11 (predicted)","termid":"PBO:0011452"}


id: PBO:0004324
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zf-C3HC4 type (RING finger)/GCN5-related N acetyltransferase fusion protein","termid":"PBO:0004324"}


id: MONDO:0016918
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"partial deletion of chromosome 20","termid":"MONDO:0016882"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"partial deletion of the long arm of chromosome 20","secondary_identifiers":["Orphanet:262164","GARD:20839","icd11.foundation:27627438","UMLS:C5679730","MEDGEN:1826048"],"synonyms":[{"name":"partial deletion of chromosome 20q","type":"exact"},{"name":"partial deletion of the long arm of chromosome type 20","type":"exact"},{"name":"partial monosomy of chromosome 20q","type":"exact"},{"name":"partial monosomy of the long arm of chromosome 20","type":"exact"}],"termid":"MONDO:0016918","xrefs":{"Monarch":{"xref_id":"0016918"}}}


id: PBO:0067296
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 381, pseudogene","termid":"PBO:0067296"}


id: GO:0006274
data:
  {"annotated_genes":["SJAG_00247","SJAG_00073","SJAG_04855"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[104091],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0071946"},{"annotations":[104096],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0071807"},{"annotations":[116885],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0071170"},{"annotations":[95165],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0071171"}]},"cv_name":"biological_process","definition":"The process in which DNA replication at a replication fork ceases; occurs when the replication fork reaches a specific termination site or when two replication forks meet.","definition_xrefs":["GOC:mah","PMID:12009298","PMID:10209736"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA metabolic process","termid":"GO:0006259"},{"relation_name":"part_of","term_name":"DNA-templated DNA replication","termid":"GO:0006261"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00073":null,"SJAG_00247":null,"SJAG_04855":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006259"},{"rel_name":"part_of","termid":"GO:0006260"},{"rel_name":"part_of","termid":"GO:0006259"}],"interesting_parent_ids":["GO:0006259","GO:0006260","GO:0008150"],"is_obsolete":false,"name":"DNA replication termination","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0006274","terms_by_termid":{"GO:0071170":null,"GO:0071171":null,"GO:0071807":null,"GO:0071946":null}}


id: PR:Q9Y7U8
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mrpl37 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9Y7U8"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"54S ribosomal protein L37, mitochondrial (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC645.09","synonyms":[{"name":"Spom972h-mrpl37","type":"exact"}],"termid":"PR:Q9Y7U8"}


id: PBO:0052446
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Kruppel like factor 2 pseudogene 3","termid":"PBO:0052446"}


id: MONDO:0019337
data:
  {"annotated_genes":["SJAG_03850"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88322],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008218"}]},"cv_name":"mondo","definition":"An autoimmune disease characterized by blisters on the skin.","direct_ancestors":[{"relation_name":"is_a","term_name":"dermatitis","termid":"MONDO:0002406"},{"relation_name":"is_a","term_name":"vesiculobullous skin disease","termid":"MONDO:0006617"},{"relation_name":"is_a","term_name":"autoimmune disease","termid":"MONDO:0007179"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03850":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005093"],"is_obsolete":false,"name":"autoimmune bullous skin disease","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["ICD9:694.8","UMLS:C5681494","EFO:0008598","GARD:19028","ICD9:694.9","SCTID:7231009","MEDGEN:1842418","Orphanet:79669","DOID:8502"],"synonyms":[{"name":"bullous dermatosis","type":"related"},{"name":"bullous skin disease","type":"broad"}],"termid":"MONDO:0019337","terms_by_termid":{"MONDO:0008218":null},"xrefs":{"Monarch":{"xref_id":"0019337"}}}


id: MONDO:0008161
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Otodental syndrome is a very rare inherited condition characterized by grossly enlarged canine and molar teeth (globodontia) associated with sensorineural hearing loss.","definition_xrefs":["Orphanet:2791"],"direct_ancestors":[{"relation_name":"is_a","term_name":"partial deletion of the long arm of chromosome 11","termid":"MONDO:0016910"},{"relation_name":"is_a","term_name":"disorder of development or morphogenesis","termid":"MONDO:0021147"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"otodental syndrome","secondary_identifiers":["MEDGEN:318937","SCTID:707310009","OMIM:166750","UMLS:C1833693","GARD:4168"],"synonyms":[{"name":"chromosome 11q13 deletion syndrome","type":"related"},{"name":"globodontia","type":"exact"},{"name":"oculootodental syndrome","type":"related"},{"name":"otodental dysplasia","type":"exact"},{"name":"otodental dysplasia chromosome deletion syndrome","type":"exact"},{"name":"otodental syndrome","type":"exact"},{"name":"otodental syndrome with coloboma","type":"related"}],"termid":"MONDO:0008161","xrefs":{"Monarch":{"xref_id":"0008161"}}}


id: MONDO:0001508
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A eustachian tube disorder with a wider eustachian tube which allows a larger bolus of bacteria-laden material from the nasopharynx during an infection to enter the middle ear, causing a more fulminant infection.","definition_xrefs":["DOID:12358"],"direct_ancestors":[{"relation_name":"is_a","term_name":"eustachian tube disorder","termid":"MONDO:0004866"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"patulous eustachian tube","secondary_identifiers":["SCTID:30280005","ICD9:381.7","UMLS:C0155434","icd11.foundation:1112306780","MEDGEN:509965","ICD10CM:H69.0"],"termid":"MONDO:0001508","xrefs":{"Monarch":{"xref_id":"0001508"}}}


id: GO:0005217
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transmembrane transfer of an ion by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts.","definition_xrefs":["ISBN:0815340729","GOC:mtg_transport"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ligand-gated monoatomic ion channel activity","termid":"GO:0015276"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0005215","GO:0003674","GO:0022857"],"is_obsolete":false,"name":"intracellularly ligand-gated monoatomic ion channel activity","synonyms":[{"name":"intracellular ligand-gated ion channel activity","type":"broad"},{"name":"intracellular ligand-gated monoatomic ion channel activity","type":"exact"}],"termid":"GO:0005217"}


id: PBO:0038483
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP binding cassette subfamily B member 8","termid":"PBO:0038483"}


id: PR:O94687
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- tas3 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O94687"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA-induced transcriptional silencing complex protein tas3 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC83.03c","synonyms":[{"name":"RITS protein tas3 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-tas3","type":"exact"}],"termid":"PR:O94687"}


id: PBO:0087251
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress","termid":"PBO:0087251"}


id: PBO:0005228
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNase MRP subunit (predicted)","termid":"PBO:0005228"}


id: PBO:0054624
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2029","termid":"PBO:0054624"}


id: PBO:0067281
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 362, pseudogene","termid":"PBO:0067281"}


id: PBO:0075039
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, C/D box 116-2","termid":"PBO:0075039"}


id: MONDO:0017090
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete midline cerebral malformation (obsolete MONDO:0017090)","secondary_identifiers":["Orphanet:268926"],"synonyms":[{"name":"Midline brain malformation","type":"exact"}],"termid":"MONDO:0017090","xrefs":{"Monarch":{"xref_id":"0017090"}}}


id: FYPO:0006926
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the ratio of the nuclear volume to the total cell volume is greater than normal (the ration observed in wild type is approximately 0.076-0.089).","definition_xrefs":["PMID:31015410","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal cellular physical quality phenotype during vegetative growth","termid":"FYPO:0004639"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"increased nucleus:cytoplasm ratio","synonyms":[{"name":"increased nuclear:cytoplasmic ratio","type":"exact"},{"name":"increased nuclear:cytoplasmic volume ratio","type":"exact"},{"name":"increased nucleus:cell volume ratio","type":"exact"},{"name":"increased nucleus:cytoplasm ratio during mitotic cell cycle","type":"related"},{"name":"increased nucleus:cytoplasm ratio during vegetative growth","type":"exact"},{"name":"increased nucleus:cytoplasm volume ratio","type":"exact"}],"termid":"FYPO:0006926"}


id: MONDO:0005847
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Atelectasis of the right middle pulmonary lobe, with chronic pneumonitis. (Dorland, 27th ed)","definition_xrefs":["MESH:D008878"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lung disorder","termid":"MONDO:0005275"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"middle lobe syndrome","secondary_identifiers":["UMLS:C0026069","DOID:2810","EFO:0007367","MEDGEN:6393","SCTID:28295001"],"termid":"MONDO:0005847","xrefs":{"Monarch":{"xref_id":"0005847"}}}


id: GO:0033920
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: a 6-phospho-beta-D-galactoside + H2O = 6-phospho-D-galactose + an alcohol.","definition_xrefs":["RHEA:24568"],"direct_ancestors":[{"relation_name":"is_a","term_name":"galactosidase activity","termid":"GO:0015925"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016798"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016798","GO:0016787"],"is_obsolete":false,"name":"6-phospho-beta-galactosidase activity","secondary_identifiers":["EC:3.2.1.85","MetaCyc:6-PHOSPHO-BETA-GALACTOSIDASE-RXN"],"synonyms":[{"name":"6-phospho-beta-D-galactosidase activity","type":"related"},{"name":"6-phospho-beta-D-galactoside 6-phosphogalactohydrolase activity","type":"related"},{"name":"beta-D-phosphogalactoside galactohydrolase activity","type":"related"},{"name":"phospho-beta-D-galactosidase activity","type":"related"},{"name":"phospho-beta-galactosidase activity","type":"related"}],"termid":"GO:0033920"}


id: PBO:0084695
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial elongation factor involved in translational elongation","termid":"PBO:0084695"}


id: GO:0080082
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the hydrolysis of glucosidic link in esculin.","definition_xrefs":["PMID:15604686"],"direct_ancestors":[{"relation_name":"is_a","term_name":"beta-glucosidase activity","termid":"GO:0008422"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016798"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016787","GO:0003824","GO:0016798","GO:0003674"],"is_obsolete":false,"name":"esculin beta-glucosidase activity","termid":"GO:0080082"}


id: GO:0047454
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: phaseollidin hydrate = H2O + phaseollidin.","definition_xrefs":["EC:4.2.1.97","RHEA:19769"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydro-lyase activity","termid":"GO:0016836"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016829"}],"interesting_parent_ids":["GO:0016829","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"phaseollidin hydratase activity","secondary_identifiers":["MetaCyc:4.2.1.97-RXN","KEGG_REACTION:R04728"],"synonyms":[{"name":"phaseollidin-hydrate hydro-lyase (phaseollidin-forming)","type":"related"},{"name":"phaseollidin-hydrate hydro-lyase activity","type":"related"}],"termid":"GO:0047454"}


id: PBO:0066135
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribonucleoprotein, PTB binding 2","termid":"PBO:0066135"}


id: GO:0010448
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The increase in size or mass of a vegetative meristem, a population of undifferentiated cells in a plant shoot which maintains a continuous balance between the production of stem cells and the incorporation of their derivatives into lateral organ primordia.","definition_xrefs":["ISBN:0849397928","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"meristem growth","termid":"GO:0035266"},{"relation_name":"is_a","term_name":"developmental vegetative growth","termid":"GO:0080186"},{"relation_name":"part_of","term_name":"shoot system development","termid":"GO:0048367"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"vegetative meristem growth","termid":"GO:0010448"}


id: PR:Q10988
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- uve1 gene.","definition_xrefs":["UniProtKB:Q10988","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UV-damage endonuclease (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC19C7.09c","synonyms":[{"name":"Spom972h-uve1","type":"exact"},{"name":"UVDE (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q10988"}


id: MONDO:0013981
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare, genetic movement disorder characterized by autosomal dominant, adult-onset, slowly progressive, multifocal, cortical myoclonus. Patients present somatosensory-evoked, brief, jerky, involuntary movements in the face, arms and legs, associated in most of cases with sustained, multiple, sudden falls without loss of consciousness. Seizures or other neurological deficits, aside from mild cerebellar ataxia late in the course of the illness, are absent.","definition_xrefs":["Orphanet:319189"],"direct_ancestors":[{"relation_name":"is_a","term_name":"movement disorder","termid":"MONDO:0005395"},{"relation_name":"is_a","term_name":"hereditary neurological disease","termid":"MONDO:0100545"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myoclonus, familial","secondary_identifiers":["GARD:17444","SCTID:763770005","OMIMPS:614937"],"synonyms":[{"name":"FCM","type":"related"},{"name":"familial cortical myoclonus","type":"exact"},{"name":"familial myoclonus","type":"exact"},{"name":"myoclonus, familial cortical","type":"exact"}],"termid":"MONDO:0013981","xrefs":{"Monarch":{"xref_id":"0013981"}}}


id: PBO:0110500
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"STMN3 pseudogene 1","termid":"PBO:0110500"}


id: GO:0042403
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.","definition_xrefs":["ISBN:0198506732","GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified amino acid metabolic process","termid":"GO:0006575"},{"relation_name":"is_a","term_name":"phenol-containing compound metabolic process","termid":"GO:0018958"},{"relation_name":"is_a","term_name":"hormone metabolic process","termid":"GO:0042445"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"thyroid hormone metabolic process","secondary_identifiers":["Reactome:R-HSA-350864"],"synonyms":[{"name":"thyroid hormone metabolism","type":"exact"}],"termid":"GO:0042403"}


id: PBO:0062778
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 56 subfamily A member 7 pseudogene","termid":"PBO:0062778"}


id: SO:0002239
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A gene which codes for 28S_rRNA, which functions as a component of the large subunit of the ribosome in eukaryotes.","direct_ancestors":[{"relation_name":"is_a","term_name":"cytosolic_LSU_rRNA_gene","termid":"SO:0002361"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytosolic_rRNA_28S_gene","synonyms":[{"name":"28S rRNA gene","type":"exact"},{"name":"28S_rRNA_gene","type":"exact"}],"termid":"SO:0002239"}


id: PBO:0067264
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 338, pseudogene","termid":"PBO:0067264"}


id: PBO:0055074
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2491","termid":"PBO:0055074"}


id: MOD:02070
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that contains an L-histidine residue coordinated to one or more metal atoms or metal clusters.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified L-histidine residue","termid":"MOD:00909"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"metal or metal cluster coordinated L-histidine residue","termid":"MOD:02070"}


id: PBO:0076502
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"taste 2 receptor member 2, pseudogene","termid":"PBO:0076502"}


id: PBO:0027531
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_ribonuclease_activity","termid":"PBO:0027531"}


id: GO:0035717
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to chemokine (C-C motif) ligand 7.","definition_xrefs":["GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"C-C chemokine binding","termid":"GO:0019957"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005488","GO:0005515","GO:0003674"],"is_obsolete":false,"name":"chemokine (C-C motif) ligand 7 binding","synonyms":[{"name":"CCL7 binding","type":"exact"}],"termid":"GO:0035717"}


id: PBO:0060508
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NSF attachment protein alpha","termid":"PBO:0060508"}


id: MOD:00418
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces a hydrogen atom with an (pyridin-3-yl)acetyl group.","definition_xrefs":["Unimod:25","PubMed:9276974"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acylated residue","termid":"MOD:00649"},{"relation_name":"is_a","term_name":"reagent derivatized residue","termid":"MOD:00848"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pyridylacetylated residue","synonyms":[{"name":"Pyridylacetyl","type":"related"},{"name":"pyridylacetyl","type":"related"}],"termid":"MOD:00418"}


id: MONDO:0007088
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"early-onset autosomal dominant Alzheimer disease","termid":"MONDO:0015140"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0002039"}],"interesting_parent_ids":["MONDO:0000426","MONDO:0002039","MONDO:0005559"],"is_obsolete":false,"name":"Alzheimer disease type 1","secondary_identifiers":["GARD:9465","UMLS:C1863052","MESH:C536594","MEDGEN:354892","DOID:0080348","OMIM:104300","DECIPHER:48"],"synonyms":[{"name":"AD","type":"related"},{"name":"AD1","type":"related"},{"name":"Alzheimer disease","type":"related"},{"name":"Alzheimer disease 1","type":"related"},{"name":"Alzheimer disease 1, familial","type":"exact"},{"name":"Alzheimer disease, early-onset, with cerebral amyloid angiopathy","type":"related"},{"name":"Alzheimer disease, familial, 1","type":"related"},{"name":"Alzheimer disease, late-onset, susceptibility to","type":"related"},{"name":"Alzheimer disease, protection against","type":"related"},{"name":"Alzheimer disease, susceptibility to","type":"related"},{"name":"early-onset familial form of Alzheimer disease","type":"broad"},{"name":"presenile and senile dementia","type":"related"}],"termid":"MONDO:0007088","xrefs":{"Monarch":{"xref_id":"0007088"}}}


id: MONDO:0015085
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Bathing suit ichthyosis (BSI) is a rare variant of autosomal recessive congenital ichthyosis (ARCI) characterized by the presence of large dark scales in specific areas of the body.","definition_xrefs":["Orphanet:100976"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive congenital ichthyosis","termid":"MONDO:0017265"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"bathing suit ichthyosis","secondary_identifiers":["SCTID:725588002","MEDGEN:1386460","GARD:16938","icd11.foundation:174005370","UMLS:C4511230"],"synonyms":[{"name":"BSI","type":"exact"}],"termid":"MONDO:0015085","xrefs":{"Monarch":{"xref_id":"0015085"}}}


id: GO:0047402
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: H2O + protein alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine = protein beta-D-galactosyl-L-hydroxylysine + beta-D-glucose. The enzyme specifically hydrolyzes glucose from alpha-D-glucosyl- (1->2)-beta-D-galactosyl disaccharide units that are linked to hydroxylysine residues of collagen and collagen-like proteins.","definition_xrefs":["MetaCyc:3.2.1.107-RXN","EC:3.2.1.107"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glucosidase activity","termid":"GO:0015926"},{"relation_name":"is_a","term_name":"catalytic activity, acting on a protein","termid":"GO:0140096"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016798"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016798","GO:0140096","GO:0003674","GO:0016787","GO:0003824"],"is_obsolete":false,"name":"protein-glucosylgalactosylhydroxylysine glucosidase activity","secondary_identifiers":["RHEA:11068"],"synonyms":[{"name":"2-O-alpha-D-glucopyranosyl-5-O-alpha-D-galactopyranosylhydroxy-L-lysine glucohydrolase activity","type":"related"},{"name":"protein-alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine glucohydrolase activity","type":"related"}],"termid":"GO:0047402"}


id: PBO:0001935
data:
  {"annotation_feature_type":"gene","cv_name":"gene_ex","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcriptionally regulates nmt1","termid":"PBO:0001935"}


id: GO:0090178
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the rate, frequency, or extent of the establishment of planar polarity involved in neural tube closure, the coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube.","definition_xrefs":["GOC:ascb_2009","GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of establishment of planar polarity","termid":"GO:0090175"},{"relation_name":"regulates","term_name":"establishment of planar polarity involved in neural tube closure","termid":"GO:0090177"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of establishment of planar polarity involved in neural tube closure","termid":"GO:0090178"}


id: PBO:0069184
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 438, pseudogene","termid":"PBO:0069184"}


id: GO:1990346
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A heterodimeric protein complex consisting of BID and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.","definition_xrefs":["PMID:14634621","GOC:bhm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex","termid":"GO:0032991"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"BID-BCL-xl complex","termid":"GO:1990346"}


id: PBO:0062235
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 5 subfamily B member 19 pseudogene","termid":"PBO:0062235"}


id: GO:1905700
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of xenobiotic transmembrane export. A xenobiotic is a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.","definition_xrefs":["GOC:krc","GOC:TermGenie","PMID:15198509","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of transmembrane transport","termid":"GO:0034763"},{"relation_name":"is_a","term_name":"regulation of xenobiotic detoxification by transmembrane export across the plasma membrane","termid":"GO:1905699"},{"relation_name":"is_a","term_name":"negative regulation of response to drug","termid":"GO:2001024"},{"relation_name":"negatively_regulates","term_name":"xenobiotic detoxification by transmembrane export across the plasma membrane","termid":"GO:1990961"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"negatively_regulates","termid":"GO:0006810"},{"rel_name":"negatively_regulates","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0055085"}],"interesting_parent_ids":["GO:0006810","GO:0055085","GO:0008150"],"is_obsolete":false,"name":"negative regulation of xenobiotic detoxification by transmembrane export across the plasma membrane","synonyms":[{"name":"down regulation of drug transmembrane export","type":"narrow"},{"name":"down-regulation of drug transmembrane export","type":"narrow"},{"name":"downregulation of drug transmembrane export","type":"narrow"},{"name":"inhibition of drug transmembrane export","type":"narrow"},{"name":"negative regulation of drug transmembrane export","type":"narrow"},{"name":"negative regulation of xenobiotic transmembrane export","type":"narrow"}],"termid":"GO:1905700"}


id: MONDO:1011434
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hypokalaemic periodic paralysis that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nutritional disorder, non-human animal","termid":"MONDO:1011338"},{"relation_name":"is_a","term_name":"hereditary neurological disease, non-human animal","termid":"MONDO:1012972"},{"relation_name":"is_a","term_name":"inborn errors of metabolism, non-human animal","termid":"MONDO:1012979"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hypokalaemic periodic paralysis, non-human animal","secondary_identifiers":["OMIA:001759"],"termid":"MONDO:1011434","xrefs":{"Monarch":{"xref_id":"1011434"}}}


id: PBO:0017985
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Schizosaccharomyces specific protein Mug20","termid":"PBO:0017985"}


id: FYPO:0006169
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to 4-nitroquinoline N-oxide.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein phosphorylation during vegetative growth","termid":"FYPO:0000776"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001312","FYPO:0001320","FYPO:0000002","FYPO:0000257"],"is_obsolete":false,"name":"normal protein phosphorylation during cellular response to 4-nitroquinoline N-oxide","synonyms":[{"name":"normal protein phosphorylation during cellular response to 4-NQO","type":"exact"},{"name":"normal protein phosphorylation during cellular response to 4-nitroquinoline N-oxide during mitotic cell cycle","type":"related"},{"name":"normal protein phosphorylation during cellular response to 4-nitroquinoline N-oxide during vegetative growth","type":"exact"},{"name":"normal protein phosphorylation during cellular response to 4NQO","type":"exact"}],"termid":"FYPO:0006169"}


id: PBO:0085033
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Non-canonical poly(A) polymerase; involved in nuclear RNA degradation as a component of TRAMP; catalyzes polyadenylation of hypomodified tRNAs, and snoRNA and rRNA precursors; required for mRNA surveillance and maintenance of genome integrity, serving as a link between RNA and DNA metabolism; overlapping but non-redundant functions with Trf5p; relocalizes to cytosol in response to hypoxia","termid":"PBO:0085033"}


id: PBO:0067413
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 524, pseudogene","termid":"PBO:0067413"}


id: PBO:0109022
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Gfo/Idh/MocA-like oxidoreductase domain containing 2","termid":"PBO:0109022"}


id: GO:2000070
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of response to water deprivation.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of response to stress","termid":"GO:0080134"},{"relation_name":"regulates","term_name":"response to water deprivation","termid":"GO:0009414"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of response to water deprivation","synonyms":[{"name":"regulation of drought tolerance","type":"related"},{"name":"regulation of response to dehydration","type":"exact"},{"name":"regulation of response to drought","type":"exact"},{"name":"regulation of response to thirst","type":"exact"}],"termid":"GO:2000070"}


id: GO:0015671
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gas transport","termid":"GO:0015669"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0051179","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"oxygen transport","secondary_identifiers":["Reactome:R-HSA-8981607"],"termid":"GO:0015671"}


id: GO:0033951
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the hydrolysis of 1,4-beta-D-xylose residues from the reducing end of oligosaccharides.","definition_xrefs":["EC:3.2.1.156"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, hydrolyzing O-glycosyl compounds","termid":"GO:0004553"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0016798"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016798","GO:0016787","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"oligosaccharide reducing-end xylanase activity","secondary_identifiers":["MetaCyc:3.2.1.156-RXN"],"synonyms":[{"name":"Rex","type":"related"},{"name":"beta-D-xylopyranosyl-(1->4)-beta-D-xylopyranosyl-(1->4)-beta-D-xylopyranose reducing-end xylanase activity","type":"related"},{"name":"reducing end xylose-releasing exo-oligoxylanase activity","type":"related"}],"termid":"GO:0033951"}


id: PBO:0062310
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 5 subfamily T member 2","termid":"PBO:0062310"}


id: PBO:0056058
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leucine rich adaptor protein 1","termid":"PBO:0056058"}


id: GO:1900259
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity.","definition_xrefs":["GOC:TermGenie","GOC:pf"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of RNA-dependent RNA polymerase activity (obsolete GO:1900259)","synonyms":[{"name":"regulation of 3D polymerase activity","type":"exact"},{"name":"regulation of Q-beta replicase activity","type":"exact"},{"name":"regulation of RDRP","type":"related"},{"name":"regulation of RNA nucleotidyltransferase (RNA-directed) activity","type":"exact"},{"name":"regulation of RNA replicase activity","type":"exact"},{"name":"regulation of RNA synthetase activity","type":"related"},{"name":"regulation of RNA-dependent RNA replicase activity","type":"exact"},{"name":"regulation of RNA-dependent ribonucleate nucleotidyltransferase activity","type":"exact"},{"name":"regulation of RNA-directed 5'-3' RNA polymerase activity","type":"exact"},{"name":"regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)","type":"exact"},{"name":"regulation of ribonucleic acid replicase activity","type":"exact"},{"name":"regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity","type":"exact"},{"name":"regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity","type":"exact"},{"name":"regulation of ribonucleic replicase activity","type":"exact"},{"name":"regulation of ribonucleic synthetase activity","type":"related"},{"name":"regulation of transcriptase","type":"broad"}],"termid":"GO:1900259"}


id: GO:0000024
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose).","definition_xrefs":["ISBN:0198506732","GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"maltose metabolic process","termid":"GO:0000023"},{"relation_name":"is_a","term_name":"disaccharide biosynthetic process","termid":"GO:0046351"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0008150","GO:0005975"],"is_obsolete":false,"name":"maltose biosynthetic process","synonyms":[{"name":"malt sugar biosynthesis","type":"exact"},{"name":"malt sugar biosynthetic process","type":"exact"},{"name":"maltose anabolism","type":"exact"},{"name":"maltose biosynthesis","type":"exact"},{"name":"maltose formation","type":"exact"},{"name":"maltose synthesis","type":"exact"}],"termid":"GO:0000024"}


id: PBO:0029577
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_protein_threonine_phosphorylation_at_Thr-Pro_site","termid":"PBO:0029577"}


id: MONDO:0017898
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. Autosomal recessive form of mendelian susceptibility to mycobacterial diseases due to a partial deficiency.","definition_xrefs":["MONDO:patterns/autosomal_recessive"],"gene_count":0,"genotype_count":0,"name":"obsolete autosomal recessive mendelian susceptibility to mycobacterial diseases due to a partial deficiency (obsolete MONDO:0017898)","secondary_identifiers":["Orphanet:319539"],"synonyms":[{"name":"autosomal recessive MSMD due to a partial deficiency","type":"exact"},{"name":"mendelian susceptibility to mycobacterial diseases due to a partial deficiency, autosomal recessive","type":"exact"}],"termid":"MONDO:0017898","xrefs":{"Monarch":{"xref_id":"0017898"}}}


id: MONDO:0957433
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"congenital anomaly of the great arteries","termid":"MONDO:0020292"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"primary pulmonary vein stenosis","secondary_identifiers":["Orphanet:642071","UMLS:C0265915","MEDGEN:539576"],"termid":"MONDO:0957433","xrefs":{"Monarch":{"xref_id":"0957433"}}}


id: MONDO:0000584
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete B cell linker protein deficiency (obsolete MONDO:0000584)","termid":"MONDO:0000584","xrefs":{"Monarch":{"xref_id":"0000584"}}}


id: PBO:0085953
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein of unknown function; null mutant is viable and displays elevated frequency of mitochondrial genome loss; null mutation confers sensitivity to tunicamycin and DTT","termid":"PBO:0085953"}


id: PR:000044730
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"The C-terminal portion of telomere maintenance protein SDE2 (Schizosaccharomyces pombe) that remains following proteolytic cleavage after the second glycine within the GGKGG motif. This portion contains a predicted helical domain.","definition_xrefs":["PomBase:VW","PRO:DAN","PMID:28947618"],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Sde2-C","pombase_gene_id":"SPAC31G5.18c","synonyms":[{"name":"PomBase_original_PRO_term_name: Sde2-C (Schizosaccharomyces pombe)","type":"exact"},{"name":"Sde2-C","type":"exact"},{"name":"Spom-sde2/Sde2-C","type":"exact"}],"termid":"PR:000044730"}


id: GO:0140592
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 8) = S-adenosyl-L-homocysteine + (histone H3-N-methyl-arginine (position 8). This reaction is the addition of a methyl group to the arginine residue at position 8 of histone H3.","definition_xrefs":["PMID:20708585","PMID:31533925"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-arginine N-methyltransferase activity","termid":"GO:0016274"},{"relation_name":"is_a","term_name":"histone H3 methyltransferase activity","termid":"GO:0140938"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0008276"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0008276","GO:0016740","GO:0140096","GO:0016741"],"is_obsolete":false,"name":"histone H3R8 methyltransferase activity","synonyms":[{"name":"histone H3R8 arginine methylase activity","type":"exact"},{"name":"histone H3R8 arginine methyltransferase activity","type":"exact"},{"name":"histone methyltransferase activity (H3-R8 specific)","type":"exact"},{"name":"histone-H3R8 methyltransferase activity","type":"exact"}],"termid":"GO:0140592"}


id: PR:P46960
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A geranylgeranyl transferase type-2 subunit beta that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR11774:SF5","PRO:DNx","OMA:SCHPO00626"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"geranylgeranyl transferase type-2 subunit beta (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC167.02","secondary_identifiers":["UniProtKB:P46960"],"synonyms":[{"name":"GGTase-II-beta (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-RABGGTB","type":"exact"},{"name":"geranylgeranyl transferase type II subunit beta (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"type II protein geranyl-geranyltransferase subunit beta (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:P46960"}


id: GO:0008798
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the cleavage of a beta-linked aspartic residue from the N-terminus of a polypeptide.","definition_xrefs":["EC:3.4.19.5"],"direct_ancestors":[{"relation_name":"is_a","term_name":"omega peptidase activity","termid":"GO:0008242"},{"relation_name":"is_a","term_name":"threonine-type peptidase activity","termid":"GO:0070003"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008233"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016787","GO:0003674","GO:0008233","GO:0140096","GO:0003824"],"is_obsolete":false,"name":"beta-aspartyl-peptidase activity","secondary_identifiers":["MetaCyc:3.4.19.5-RXN","Reactome:R-HSA-5692495"],"synonyms":[{"name":"beta-aspartyl dipeptidase activity","type":"related"},{"name":"beta-aspartyl peptidase activity","type":"related"}],"termid":"GO:0008798"}


id: PBO:0030453
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_homocitrate_synthase_activity","termid":"PBO:0030453"}


id: MONDO:0006942
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete reflex epilepsy (obsolete MONDO:0006942)","termid":"MONDO:0006942","xrefs":{"Monarch":{"xref_id":"0006942"}}}


id: GO:1900244
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of synaptic vesicle endocytosis.","definition_xrefs":["GOC:TermGenie","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of endocytosis","termid":"GO:0045807"},{"relation_name":"is_a","term_name":"regulation of synaptic vesicle endocytosis","termid":"GO:1900242"},{"relation_name":"is_a","term_name":"positive regulation of synaptic vesicle recycling","termid":"GO:1903423"},{"relation_name":"positively_regulates","term_name":"synaptic vesicle endocytosis","termid":"GO:0048488"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0016192"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"positively_regulates","termid":"GO:0016192"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0016192","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"positive regulation of synaptic vesicle endocytosis","synonyms":[{"name":"activation of synaptic vesicle endocytosis","type":"narrow"},{"name":"activation of synaptic vesicle retrieval","type":"related"},{"name":"positive regulation of synaptic vesicle retrieval","type":"related"},{"name":"up regulation of synaptic vesicle endocytosis","type":"exact"},{"name":"up regulation of synaptic vesicle retrieval","type":"related"},{"name":"up-regulation of synaptic vesicle endocytosis","type":"exact"},{"name":"up-regulation of synaptic vesicle retrieval","type":"related"},{"name":"upregulation of synaptic vesicle endocytosis","type":"exact"},{"name":"upregulation of synaptic vesicle retrieval","type":"related"}],"termid":"GO:1900244"}


id: MONDO:0011774
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any autosomal recessive nonsyndromic deafness in which the cause of the disease is a mutation in the MYO3A gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hearing loss, autosomal recessive","termid":"MONDO:0019588"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0019497"}],"interesting_parent_ids":["MONDO:0019497","MONDO:0006025"],"is_obsolete":false,"name":"autosomal recessive nonsyndromic hearing loss 30","secondary_identifiers":["UMLS:C1846784","DOID:0110489","GARD:22603","OMIM:607101","MESH:C564624","MEDGEN:335521"],"synonyms":[{"name":"DFNB30","type":"narrow"},{"name":"MYO3A autosomal recessive nonsyndromic deafness","type":"narrow"},{"name":"autosomal recessive deafness 30","type":"narrow"},{"name":"autosomal recessive nonsyndromic deafness 30","type":"narrow"},{"name":"autosomal recessive nonsyndromic deafness caused by mutation in MYO3A","type":"narrow"},{"name":"autosomal recessive nonsyndromic deafness type 30","type":"narrow"},{"name":"autosomal recessive nonsyndromic hearing loss 30","type":"exact"},{"name":"deafness, autosomal recessive 30","type":"narrow"},{"name":"deafness, autosomal recessive type 30","type":"narrow"}],"termid":"MONDO:0011774","xrefs":{"Monarch":{"xref_id":"0011774"}}}


id: PBO:0079454
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tumor suppressor candidate 7","termid":"PBO:0079454"}


id: GO:0031997
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Binding to the N-terminus of a protein that has the potential to be, or has been, modified by N-terminal myristoylation. Binding affinity is typically altered by myristoylation; for example, N-terminal myristoylation of HIV Nef increases its affinity for calmodulin.","definition_xrefs":["GOC:dl","PMID:15632291","GOC:jsg"],"gene_count":0,"genotype_count":0,"name":"obsolete N-terminal myristoylation domain binding (obsolete GO:0031997)","termid":"GO:0031997"}


id: GO:1990309
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a type-II dockerin domain of a protein. Type-II dockerin domain is the binding partner of type-II cohesin domain.","definition_xrefs":["PMID:23195689","PMID:24080387","GOC:mengo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein domain specific binding","termid":"GO:0019904"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0003674","GO:0005488","GO:0005515"],"is_obsolete":false,"name":"type-II dockerin domain binding","termid":"GO:1990309"}


id: GO:0102874
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 1-16:0-2-18:2-digalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-16:0-2-18:3-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.","definition_xrefs":["PMID:17064923","GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete 1-16:0-2-18:2-digalactosyldiacylglycerol desaturase activity (obsolete GO:0102874)","termid":"GO:0102874"}


id: GO:0010062
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that suppresses trichoblast fate specification.","definition_xrefs":["GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cell fate specification","termid":"GO:0009996"},{"relation_name":"is_a","term_name":"regulation of trichoblast fate specification","termid":"GO:0010061"},{"relation_name":"is_a","term_name":"negative regulation of plant epidermal cell differentiation","termid":"GO:1903889"},{"relation_name":"negatively_regulates","term_name":"trichoblast fate specification","termid":"GO:0010057"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of trichoblast fate specification","synonyms":[{"name":"down regulation of trichoblast fate","type":"exact"},{"name":"down-regulation of trichoblast fate","type":"exact"},{"name":"downregulation of trichoblast fate","type":"exact"},{"name":"inhibition of trichoblast fate","type":"narrow"}],"termid":"GO:0010062"}


id: GO:1902675
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"Any ciliary basal body that is part of a left ventral flagellum found in Giardia species (trophozoite stage).","definition_xrefs":["GOC:giardia","PMID:5961344","GOC:TermGenie","PMID:16607022","ISBN:9780124260207","GO_REF:0000064"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ciliary basal body","termid":"GO:0036064"},{"relation_name":"part_of","term_name":"left ventral flagellum","termid":"GO:0097558"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0015630"}],"interesting_parent_ids":["GO:0005575","GO:0015630"],"is_obsolete":false,"name":"left ventral basal body","synonyms":[{"name":"cilial basal body of left ventral cilium","type":"exact"},{"name":"cilial basal body of left ventral flagellum","type":"exact"},{"name":"ciliary basal body of left ventral cilium","type":"exact"},{"name":"ciliary basal body of left ventral flagellum","type":"exact"},{"name":"cilium basal body of left ventral cilium","type":"exact"},{"name":"cilium basal body of left ventral flagellum","type":"exact"},{"name":"left ventral flagellum ciliary basal body","type":"exact"},{"name":"microtubule basal body of left ventral cilium","type":"exact"},{"name":"microtubule basal body of left ventral flagellum","type":"exact"}],"termid":"GO:1902675"}


id: MONDO:0005699
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A form of actinomycosis characterized by slow-growing inflammatory lesions of the lymph nodes that drain the mouth (lumpy jaw), reddening of the overlying skin, and intraperitoneal abscesses.","definition_xrefs":["MESH:D000197"],"direct_ancestors":[{"relation_name":"is_a","term_name":"actinomycosis","termid":"MONDO:0005631"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cervicofacial actinomycosis","secondary_identifiers":["icd11.foundation:185601767","ICD9:039.3","UMLS:C0001264","MEDGEN:1308","ICD10CM:A42.2","NCIT:C34351","SCTID:23014006"],"synonyms":[{"name":"cervicofacial actinomycotic infection","type":"related"},{"name":"lumpy jaw","type":"related"}],"termid":"MONDO:0005699","xrefs":{"Monarch":{"xref_id":"0005699"}}}


id: MONDO:0010949
data:
  {"annotated_genes":["SJAG_03137","SJAG_03072"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87112,87113],"is_not":false,"summary":null,"term":"MONDO:0010949"}]},"cv_name":"mondo","definition":"Autosomal dominant Charcot-Marie-Tooth disease type 2B (CMT2B) is a severe form of axonal Charcot-Marie-Tooth disease, a peripheral sensorimotor neuropathy. CMT2B onset, in the 2nd or 3rd decade, is characterized by ulcerations and infections of feet. Symmetric and distal weakness develops mostly in the legs together with a severe symmetric distal sensory loss, tendon reflexes are only reduced at ankles and foot deformities, including pes cavus or planus and hammer toes, appear in childhood.","definition_xrefs":["Orphanet:99936"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Charcot-Marie-Tooth disease type 2","termid":"MONDO:0018993"}],"gene_count":2,"genes_by_uniquename":{"SJAG_03072":null,"SJAG_03137":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0005244"],"is_obsolete":false,"name":"Charcot-Marie-Tooth disease type 2B","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["SCTID:717008005","UMLS:C1833219","DOID:0110159","icd11.foundation:1425224652","MESH:C537989","GARD:9192","MEDGEN:371512","OMIM:600882"],"synonyms":[{"name":"CMT 2B","type":"related"},{"name":"CMT2B","type":"exact"},{"name":"Charcot Marie Tooth disease type 2B","type":"related"},{"name":"Charcot-Marie-Tooth disease type 2 caused by mutation in RAB7A","type":"exact"},{"name":"Charcot-Marie-Tooth disease, autosomal dominant, type 2B","type":"related"},{"name":"Charcot-Marie-Tooth disease, axonal, type 2B","type":"related"},{"name":"Charcot-Marie-Tooth disease, neuronal, type 2B","type":"related"},{"name":"Charcot-Marie-Tooth disease, type 2B","type":"exact"},{"name":"Charcot-Marie-Tooth neuropathy type 2B","type":"exact"},{"name":"Charcot-Marie-Tooth neuropathy, type 2B","type":"related"},{"name":"HMSN IIB","type":"exact"},{"name":"HMSN2B","type":"exact"},{"name":"RAB7A Charcot-Marie-Tooth disease type 2","type":"exact"},{"name":"autosomal dominant Charcot-Marie-Tooth disease type 2B","type":"exact"},{"name":"hereditary motor and sensory neuropathy 2 B (HMSN 2 B)","type":"related"},{"name":"hereditary motor and sensory neuropathy 2B","type":"related"},{"name":"hereditary motor and sensory nueropathy IIB","type":"exact"},{"name":"peripheral sensory neuropathy, autosomal dominant (PSN)","type":"related"}],"termid":"MONDO:0010949","terms_by_termid":{"MONDO:0010949":null},"xrefs":{"Monarch":{"xref_id":"0010949"}}}


id: GO:0038092
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals initiated by nodal protein binding to an activin receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.","definition_xrefs":["GOC:BHF","GOC:vk","PMID:17287255"],"direct_ancestors":[{"relation_name":"is_a","term_name":"activin receptor signaling pathway","termid":"GO:0032924"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"nodal signaling pathway","synonyms":[{"name":"nodal signaling","type":"exact"},{"name":"nodal signalling pathway","type":"exact"}],"termid":"GO:0038092"}


id: PBO:0066376
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RDM1 pseudogene 3","termid":"PBO:0066376"}


id: PBO:0044424
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome P450 family 3 subfamily A member 43","termid":"PBO:0044424"}


id: PBO:0079981
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"USP9Y pseudogene 19","termid":"PBO:0079981"}


id: PBO:0086563
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative protein of unknown function; conserved among S. cerevisiae strains; YMR122C is not an essential gene","termid":"PBO:0086563"}


id: MOD:00985
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively substitutes a hydrogen atom of an L-tyrosine residue with a halogen atom.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"halogen containing residue","termid":"MOD:00694"},{"relation_name":"is_a","term_name":"modified L-tyrosine residue","termid":"MOD:00919"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"halogenated tyrosine","synonyms":[{"name":"HalTyr","type":"exact"}],"termid":"MOD:00985"}


id: PBO:0091835
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial matrix protein, YjgF family protein Mmf1, reactive intermediate imine deaminase A homolog Mmf1","termid":"PBO:0091835"}


id: PBO:0054001
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1326","termid":"PBO:0054001"}


id: CHEBI:49976
data:
  {"annotation_feature_type":"gene","cv_name":"chebi_ontology","direct_ancestors":[{"relation_name":"is_a","term_name":"chemical entity","termid":"CHEBI:24431"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc dichloride","termid":"CHEBI:49976"}


id: PBO:0082332
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATPase subunit of imitation-switch (ISWI) class chromatin remodelers; with Ioc3p forms Isw1a complex involved in repression of transcription initiation; with Ioc2p and Ioc4p forms Isw1b complex involved in regulation of transcription elongation; Isw1b recruited to ORFs by H3K36 methylation and acts with Chd1p to prevent trans-histone exchange over coding regions; Isw1p import into nucleus depends on C-terminal bipartite nuclear targeting signal KRIR X19 KKAK","termid":"PBO:0082332"}


id: PBO:0002571
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA polymerase II associated Paf1 complex subunit Tpr1","termid":"PBO:0002571"}


id: PBO:0066243
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA binding motif single stranded interacting protein 1","termid":"PBO:0066243"}


id: PBO:0084044
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"G protein beta subunit; forms a dimer with Ste18p to activate mating signaling pathway, forms heterotrimer with Gpa1p and Ste18p to dampen signaling; pheromone-induced phosphorylation plays critical role in chemotropism; may recruit Rho1p to polarized growth site during mating; contains WD40 repeats","termid":"PBO:0084044"}


id: GO:0052083
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A process by which a symbiont interferes with, inhibits or disrupts the normal execution of the cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"gene_count":0,"genotype_count":0,"name":"obsolete symbiont-mediated suppression of host cell-mediated immune response (obsolete GO:0052083)","synonyms":[{"name":"down regulation by symbiont of host cell-mediated immune response","type":"exact"},{"name":"down-regulation by symbiont of host cell-mediated immune response","type":"exact"},{"name":"downregulation by symbiont of host cell-mediated immune response","type":"exact"},{"name":"inhibition by symbiont of host cell-mediated immune response","type":"narrow"},{"name":"negative regulation by organism of cell-mediated immune response of other organism involved in symbiotic interaction","type":"broad"},{"name":"suppression by symbiont of host cell-mediated immune response","type":"exact"}],"termid":"GO:0052083"}


id: GO:0033394
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 1,3 diaminopropane.","definition_xrefs":["MetaCyc:PWY-3981","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"beta-alanine biosynthetic process","termid":"GO:0019483"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006520"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0006520","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"beta-alanine biosynthetic process via 1,3 diaminopropane","synonyms":[{"name":"beta-alanine anabolism via 1,3 diaminopropane","type":"exact"},{"name":"beta-alanine biosynthesis via 1,3 diaminopropane","type":"exact"},{"name":"beta-alanine formation via 1,3 diaminopropane","type":"exact"},{"name":"beta-alanine synthesis via 1,3 diaminopropane","type":"exact"}],"termid":"GO:0033394"}


id: PBO:0045141
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dynein axonemal assembly factor 10","termid":"PBO:0045141"}


id: FYPO:0002971
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is decreased during telophase.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased protein localization to mitotic spindle pole body during mitosis","termid":"FYPO:0002822"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0001985","FYPO:0005447","FYPO:0000002","FYPO:0000138"],"is_obsolete":false,"name":"decreased protein localization to mitotic spindle pole body during telophase","synonyms":[{"name":"decreased protein localisation to mitotic spindle pole body during telophase","type":"exact"},{"name":"decreased protein localization to mitotic SPB during telophase","type":"exact"},{"name":"decreased protein localization to mitotic spindle pole body during mitotic telophase","type":"exact"},{"name":"decreased protein localization to spindle pole body during telophase during vegetative growth","type":"exact"},{"name":"reduced protein localization to mitotic spindle pole body during telophase","type":"exact"}],"termid":"FYPO:0002971"}


id: PBO:0049449
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GXYLT1 pseudogene 3","termid":"PBO:0049449"}


id: MONDO:0004610
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete multiple carboxylase deficiency (obsolete MONDO:0004610)","termid":"MONDO:0004610","xrefs":{"Monarch":{"xref_id":"0004610"}}}


id: GO:0022015
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The division of a radial glial cell in the pallium. A radial glial cell is a precursor cell that gives rise to neurons and astrocytes.","definition_xrefs":["GOC:jid","GO_REF:0000021","GOC:cls","GOC:dgh","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell division","termid":"GO:0051301"},{"relation_name":"part_of","term_name":"pallium cell proliferation in forebrain","termid":"GO:0022013"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"radial glial cell division in pallium","termid":"GO:0022015"}


id: PBO:0043185
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chondrogenesis-associated transcript","termid":"PBO:0043185"}


id: PBO:0016513
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-causally_upstream_of","termid":"PBO:0016513"}


id: GO:0070818
data:
  {"annotated_genes":["SJAG_02876"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[74291],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004729"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: protoporphyrinogen IX + acceptor = protoporphyrin IX + reduced acceptor.","definition_xrefs":["GOC:mah","PMID:19583219"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-CH group of donors","termid":"GO:0016627"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02876":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"protoporphyrinogen oxidase activity","references_by_uniquename":{"GO_REF:0000033":null},"synonyms":[{"name":"protoporphyrinogen IX oxidase activity","type":"related"},{"name":"protoporphyrinogen-IX oxidase activity","type":"related"},{"name":"protoporphyrinogenase activity","type":"related"}],"termid":"GO:0070818","terms_by_termid":{"GO:0004729":null}}


id: PBO:0001888
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"identical paralog","termid":"PBO:0001888"}


id: GO:0032649
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.","definition_xrefs":["GOC:add","PMID:15546383","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cytokine production","termid":"GO:0001817"},{"relation_name":"regulates","term_name":"type II interferon production","termid":"GO:0032609"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"regulation of type II interferon production","secondary_identifiers":["GO:0045072","GO:1902713"],"synonyms":[{"name":"regulation of interferon-gamma biosynthetic process","type":"narrow"},{"name":"regulation of interferon-gamma production","type":"exact"},{"name":"regulation of interferon-gamma secretion","type":"narrow"}],"termid":"GO:0032649"}


id: GO:1990450
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a linear polymer of ubiquitin. Linear ubiquitin polymers are formed by linking the amino-terminal methionine (M1) of one ubiquitin molecule to the carboxy-terminal glycine (G76) of the next.","definition_xrefs":["GOC:bf","GOC:PARL","PMID:23453807"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ubiquitin binding","termid":"GO:0043130"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005515","GO:0005488","GO:0003674"],"is_obsolete":false,"name":"linear polyubiquitin binding","synonyms":[{"name":"M1-linked ubiquitin chain binding","type":"exact"}],"termid":"GO:1990450"}


id: PBO:0043206
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CKMT2 antisense RNA 1","termid":"PBO:0043206"}


id: MONDO:0021350
data:
  {"annotated_genes":["SJAG_03720","SJAG_03689","SJAG_00757","SJAG_04206","SJAG_01410","SJAG_02426","SJAG_04502","SJAG_03453","SJAG_00079","SJAG_02460","SJAG_04114","SJAG_04394","SJAG_00229"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[89137,89135,87988,87985,87984,87986,89134,89138,87987,89136],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0016419"},{"annotations":[88601,89153,88600],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008903"},{"annotations":[88138],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011014"}]},"cv_name":"mondo","definition":"A neoplasm (disease) that involves the thoracic segment of trunk.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neoplasm","termid":"MONDO:0005070"}],"gene_count":13,"genes_by_uniquename":{"SJAG_00079":null,"SJAG_00229":null,"SJAG_00757":null,"SJAG_01410":null,"SJAG_02426":null,"SJAG_02460":null,"SJAG_03453":null,"SJAG_03689":null,"SJAG_03720":null,"SJAG_04114":null,"SJAG_04206":null,"SJAG_04394":null,"SJAG_04502":null},"genotype_count":0,"is_obsolete":false,"name":"neoplasm of thorax","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["NCIT:C3406","MEDGEN:11793","UMLS:C0039981","ICD9:239.89","ICD10CM:C30-C39","SCTID:255058005"],"synonyms":[{"name":"neoplasm of the thorax","type":"exact"},{"name":"neoplasm of thoracic segment of trunk","type":"exact"},{"name":"thoracic neoplasm","type":"exact"},{"name":"thoracic segment of trunk neoplasm","type":"exact"},{"name":"thoracic segment of trunk neoplasm (disease)","type":"exact"},{"name":"thoracic segment of trunk tumor","type":"exact"},{"name":"thoracic segment of trunk tumour","type":"exact"},{"name":"thoracic tumor","type":"exact"},{"name":"thoracic tumour","type":"exact"},{"name":"tumor of the thorax","type":"exact"},{"name":"tumor of thoracic segment of trunk","type":"exact"},{"name":"tumor of thorax","type":"exact"},{"name":"tumour of the thorax","type":"exact"},{"name":"tumour of thoracic segment of trunk","type":"exact"},{"name":"tumour of thorax","type":"exact"}],"termid":"MONDO:0021350","terms_by_termid":{"MONDO:0008903":null,"MONDO:0011014":null,"MONDO:0016419":null},"xrefs":{"Monarch":{"xref_id":"0021350"}}}


id: MONDO:0001738
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete osteopetrosis (obsolete MONDO:0001738)","termid":"MONDO:0001738","xrefs":{"Monarch":{"xref_id":"0001738"}}}


id: MONDO:0007390
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coumarin resistance","secondary_identifiers":["MEDGEN:148193","MESH:C563039","OMIM:122700","SCTID:726543008","UMLS:C0750384","DOID:0080665"],"synonyms":[{"name":"coumarin resistance","type":"exact"},{"name":"coumarin sensitivity","type":"related"},{"name":"coumarin, poor metabolism of","type":"related"},{"name":"warfarin resistance","type":"related"},{"name":"warfarin sensitivity","type":"related"}],"termid":"MONDO:0007390","xrefs":{"Monarch":{"xref_id":"0007390"}}}


id: MONDO:1011041
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hereditary lack of melanin pigmentation in Mexican tetra due to a variation in the OCA2 gene.","definition_xrefs":["PMID:24282555"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oculocutaneous albinism, non-human animal","termid":"MONDO:1012579"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"oculocutaneous albinism, OCA2-related, Mexican tetra","secondary_identifiers":["OMIA:002130-7994"],"termid":"MONDO:1011041","xrefs":{"Monarch":{"xref_id":"1011041"}}}


id: FYPO:0005941
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which meiotic DNA double-strand break clipping is normal (i.e. indistinguishable from wild type). Meiotic DNA double-strand break clipping is the process by which SPO11/Rec12-oligonucleotide complexes are removed from 5' DNA double-strand breaks induced during meiosis.","definition_xrefs":["PomBase:mah","GO:1990898"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal meiotic cell cycle process","termid":"FYPO:0007078"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000257"],"is_obsolete":false,"name":"normal meiotic DNA double-strand break clipping","termid":"FYPO:0005941"}


id: MONDO:1011956
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"musculoskeletal system disorder, non-human animal","termid":"MONDO:1011335"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"growth-hormone-receptor deficiency dwarfism, non-human animal","secondary_identifiers":["OMIA:001294"],"termid":"MONDO:1011956","xrefs":{"Monarch":{"xref_id":"1011956"}}}


id: PBO:0070948
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L18a pseudogene 3","termid":"PBO:0070948"}


id: GO:1904956
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of midbrain dopaminergic neuron differentiation.","definition_xrefs":["PMID:21347250","GOC:PARL","GOC:TermGenie","GO_REF:0000058","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of dopaminergic neuron differentiation","termid":"GO:1904338"},{"relation_name":"regulates","term_name":"midbrain dopaminergic neuron differentiation","termid":"GO:1904948"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of midbrain dopaminergic neuron differentiation","synonyms":[{"name":"regulation of DA neurogenesis from midbrain floor plate","type":"exact"},{"name":"regulation of mDA neuron differentiation","type":"exact"},{"name":"regulation of midbrain DA neurogenesis","type":"exact"},{"name":"regulation of midbrain dopaminergic neuron production","type":"exact"}],"termid":"GO:1904956"}


id: FYPO:0003374
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of coenzyme Q10 measured in a cell is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal level of substance in cell during vegetative growth","termid":"FYPO:0001316"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000257","FYPO:0001320","FYPO:0001312"],"is_obsolete":false,"name":"normal cellular coenzyme Q10 level","synonyms":[{"name":"normal cellular coenzyme Q10 accumulation","type":"related"},{"name":"normal cellular coenzyme Q10 level during mitotic cell cycle","type":"related"},{"name":"normal cellular coenzyme Q10 level during vegetative growth","type":"exact"}],"termid":"FYPO:0003374"}


id: MONDO:0007204
data:
  {"annotated_genes":["SJAG_00288"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88497],"is_not":false,"summary":null,"term":"MONDO:0007204"}]},"cv_name":"mondo","definition":"Any Cole-Carpenter syndrome in which the cause of the disease is a mutation in the P4HB gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Cole-Carpenter syndrome","termid":"MONDO:0016085"},{"relation_name":"is_a","term_name":"osteogenesis imperfecta and a reduction of bone mineral density.","termid":"MONDO:0800064"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00288":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"Cole-Carpenter syndrome 1","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1374755","OMIM:112240","UMLS:C4317154"],"synonyms":[{"name":"CLCRP1","type":"related"},{"name":"COLE-CARPENTER syndrome 1","type":"related"},{"name":"Cole-Carpenter syndrome 1","type":"exact"},{"name":"Cole-Carpenter syndrome caused by mutation in P4HB","type":"exact"},{"name":"Cole-Carpenter syndrome type 1","type":"exact"},{"name":"P4HB Cole-Carpenter syndrome","type":"exact"},{"name":"bone fragility with craniosynostosis, ocular proptosis, hydrocephalus, and distinctive Facial features","type":"related"}],"termid":"MONDO:0007204","terms_by_termid":{"MONDO:0007204":null},"xrefs":{"Monarch":{"xref_id":"0007204"}}}


id: PBO:0040424
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATPase H+ transporting V0 subunit e1 pseudogene 1","termid":"PBO:0040424"}


id: GO:0043888
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: (2E,6E,10E)-geranylgeranyl diphosphate + sn-3-O-(geranylgeranyl)glycerol 1-phosphate = 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + diphosphate.","definition_xrefs":["PMID:16494480","PMID:15356000"],"gene_count":0,"genotype_count":0,"name":"obsolete (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity (obsolete GO:0043888)","synonyms":[{"name":"2,3-dGGGPS","type":"exact"},{"name":"DGGGP synthase activity","type":"exact"},{"name":"DGGGPS","type":"exact"},{"name":"UbiA","type":"related"}],"termid":"GO:0043888"}


id: PBO:0069964
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1258, pseudogene","termid":"PBO:0069964"}


id: PBO:0077387
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein 127","termid":"PBO:0077387"}


id: PR:O13984
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A replication-associated recombination protein A that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO01708","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATPase WRNIP1 homolog C26H5.02c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC26H5.02c","secondary_identifiers":["UniProtKB:O13984"],"synonyms":[{"name":"Spom972h-rarA","type":"exact"}],"termid":"PR:O13984"}


id: PBO:0066292
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA binding motif protein Y-linked family 2 member T, pseudogene","termid":"PBO:0066292"}


id: MONDO:0044219
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. The Duffy blood group system, which consists of 4 alleles, 5 phenotypes, and 5 antigens, is important in clinical medicine because of transfusion incompatibilities and hemolytic disease of the newborn. Duffy antigens are located on ACKR1 (OMIM:613665), or DARC, an acidic glycoprotein found on erythrocytes and other cells throughout the body. The 2 principal antigens, Fy(a) and Fy(b), are produced by the FYA and FYB codominant alleles (see {613665.0001}). Four phenotypes are defined by the corresponding antibodies, anti-Fy(a) and anti-Fy(b): Fy(a+b-), Fy(a-b+), Fy(a+b+), and Fy(a-b-). Fy(a-b-), or Duffy null, is the major phenotype in African and American blacks and is characterized by the presence of Fy(b) on nonerythroid cells, but an absence of Fy(b) on erythrocytes. The Fy(a-b-) phenotype is associated with complete resistance to infection by the malarial parasite Plasmodium vivax (see OMIM:611162). Individuals with the Fy(a-b-) phenotype have the FYB-erythroid silent (FYB-ES) allele with a mutation in the DARC promoter ({613665.0002}). A fifth phenotype, Fy(bwk), or Fy(x), is characterized by weak Fy(b) expression on erythrocytes due to a reduced amount of protein. Individuals with the Fy(bwk) phenotype have the FYB-weak (FYB-WK) allele, also called the FYX allele, with a missense mutation in DARC ({613665.0003}). Other Duffy antigens include Fy3, Fy4, Fy5, and Fy6 (reviews by {21:Pogo and Chaudhuri (2000)}, {10:Langhi and Bordin (2006)}, and {14:Meny (2010)}).","definition_xrefs":["OMIM:110700"],"gene_count":0,"genotype_count":0,"name":"obsolete blood group, duffy system (obsolete MONDO:0044219)","synonyms":[{"name":"Duffy blood Group system","type":"related"},{"name":"FY","type":"related"},{"name":"Plasmodium vivax, resistance to","type":"related"},{"name":"blood group, DUFFY system","type":"related"},{"name":"blood group, Duffy system","type":"exact"}],"termid":"MONDO:0044219","xrefs":{"Monarch":{"xref_id":"0044219"}}}


id: MONDO:0018510
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A neoplasm with neuroendocrine differentiation that arises from the small intestine. It includes well differentiated neuroendocrine tumors (low and intermediate grade) and poorly differentiated neuroendocrine carcinomas (high grade).","definition_xrefs":["NCIT:C5803"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"small intestine cancer","termid":"MONDO:0000956"},{"relation_name":"is_a","term_name":"intestinal neuroendocrine neoplasm","termid":"MONDO:0002883"},{"relation_name":"is_a","term_name":"small intestine neoplasm","termid":"MONDO:0004251"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"small intestine neuroendocrine neoplasm","secondary_identifiers":["EFO:1001928","UMLS:C1336005","MEDGEN:233453","DOID:4434","GARD:21765","Orphanet:423975"],"synonyms":[{"name":"NET of the small intestine","type":"exact"},{"name":"neuroendocrine neoplasm of small intestine","type":"exact"},{"name":"neuroendocrine neoplasm of the small intestine","type":"exact"},{"name":"neuroendocrine tumor of small bowel","type":"exact"},{"name":"neuroendocrine tumor of the small intestine","type":"related"},{"name":"neuroendocrine tumour of small bowel","type":"exact"},{"name":"neuroendocrine tumour of the small intestine","type":"related"},{"name":"small intestinal neuroendocrine neoplasm","type":"exact"},{"name":"small intestine NET","type":"exact"},{"name":"small intestine neuroendocrine neoplasm","type":"exact"},{"name":"small intestine neuroendocrine tumor","type":"exact"},{"name":"small intestine neuroendocrine tumor, well differentiated, low or intermediate grade","type":"related"},{"name":"small intestine neuroendocrine tumour","type":"exact"}],"termid":"MONDO:0018510","xrefs":{"Monarch":{"xref_id":"0018510"}}}


id: FYPO:0000675
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A transport phenotype observed in the vegetative growth phase of the life cycle in which protein targeting is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal intracellular protein transport during vegetative growth","termid":"FYPO:0000215"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000138","FYPO:0001320","FYPO:0005447","FYPO:0000002"],"is_obsolete":false,"name":"abnormal protein targeting during vegetative growth","synonyms":[{"name":"abnormal protein targeting during mitotic cell cycle","type":"related"}],"termid":"FYPO:0000675"}


id: PBO:0045479
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"desmocollin 1","termid":"PBO:0045479"}


id: MONDO:0100406
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any acute myeloid leukemia that has the chromosomal anomaly inv(16)(p13.3;q24.3). (A pericentric chromosomal inversion that involves chromosome 16. It is associated with CBFA2T3/GLIS2 fusions and pediatric acute megakaryoblastic leukemia.)","definition_xrefs":["NCIT:C167195"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acute myeloid leukemia","termid":"MONDO:0018874"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005570","MONDO:0004992"],"is_obsolete":false,"name":"acute myeloid leukemia, inv(16)(p13.3;q24.3)","synonyms":[{"name":"AML, inv(16)(p13.3;q24.3)","type":"exact"},{"name":"AML, inv(16)(p13.3q24.3)","type":"exact"},{"name":"AML, inv(16)(p13;q24)","type":"exact"},{"name":"AML, inv(16)(p13q24)","type":"exact"}],"termid":"MONDO:0100406","xrefs":{"Monarch":{"xref_id":"0100406"}}}


id: PATO:0001217
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0001217 energy_unit (obsolete PATO:0001217)","termid":"PATO:0001217"}


id: GO:0001207
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The removal of histones, including histone dimers, from nucleosomes within chromatin.","definition_xrefs":["GOC:krc","PMID:17496903","PMID:21807128","PMID:15525516"],"gene_count":0,"genotype_count":0,"name":"obsolete histone displacement (obsolete GO:0001207)","termid":"GO:0001207"}


id: PBO:0049540
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"H2B clustered histone 4","termid":"PBO:0049540"}


id: MONDO:0015734
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Rectal duplication is a rare congenital anorectal malformation characterized by an egg-like, cystic, mucus-filled mass, composed of intestinal mucosal lining and smooth muscle tissue. Commonly they present in childhood with symptoms of recurrent urinary tract infections, gastroenteritis, obstruction, perianal sepsis and rectal bleeding. Drainage of mucus or pus from the anus is also a typical presenting sign. The majority are found in the retro-rectal space where they communicate with, or are contiguous to, the rectum.","definition_xrefs":["Orphanet:171220"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anorectal malformation","termid":"MONDO:0019938"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"rectal duplication","secondary_identifiers":["GARD:20122","MEDGEN:1393874","SCTID:725910009","icd11.foundation:1354283575","UMLS:C4511483"],"termid":"MONDO:0015734","xrefs":{"Monarch":{"xref_id":"0015734"}}}


id: GO:0019156
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages in glycogen, amylopectin and their beta-limits dextrins.","definition_xrefs":["EC:3.2.1.68"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, hydrolyzing O-glycosyl compounds","termid":"GO:0004553"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016798"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016798","GO:0003824","GO:0003674","GO:0016787"],"is_obsolete":false,"name":"isoamylase activity","secondary_identifiers":["MetaCyc:3.2.1.68-RXN"],"synonyms":[{"name":"debranching enzyme activity","type":"broad"},{"name":"glycogen alpha-1,6-glucanohydrolase activity","type":"related"}],"termid":"GO:0019156"}


id: PBO:0058456
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 5100","termid":"PBO:0058456"}


id: MONDO:0022921
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete short stature-microcephaly-heart defect syndrome (obsolete MONDO:0022921)","secondary_identifiers":["Orphanet:2861"],"synonyms":[{"name":"d'ercole syndrome","type":"related"},{"name":"short stature microcephaly heart defect","type":"related"}],"termid":"MONDO:0022921","xrefs":{"Monarch":{"xref_id":"0022921"}}}


id: MONDO:0800468
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any muscular channelopathy in which the cause of the disease is a variation in the SCN4 gene. This is characteristic of a continuum in the clinical spectrum that includes sodium-channel myotonia, paramyotonia congenita, hypokalemic periodic paralysis type II and hyperkalemic periodic paralysis.","definition_xrefs":["MONDO:patterns/disease_series_by_gene","PMID:32849172"],"direct_ancestors":[{"relation_name":"is_a","term_name":"muscular channelopathy","termid":"MONDO:0019119"},{"relation_name":"is_a","term_name":"hereditary neuromuscular disease","termid":"MONDO:0100546"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SCN4A-related channelopathy","synonyms":[{"name":"SCN4A-related channelopathy","type":"exact"}],"termid":"MONDO:0800468","xrefs":{"Monarch":{"xref_id":"0800468"}}}


id: MONDO:0014684
data:
  {"annotated_genes":["SJAG_00255"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86882],"is_not":false,"summary":null,"term":"MONDO:0014684"}]},"cv_name":"mondo","definition":"Any combined oxidative phosphorylation deficiency in which the cause of the disease is a mutation in the TRMT5 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"combined oxidative phosphorylation deficiency","termid":"MONDO:0000732"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00255":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0004069","MONDO:0005066"],"is_obsolete":false,"name":"combined oxidative phosphorylation defect type 26","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["DOID:0111490","MEDGEN:1799164","Orphanet:477684","UMLS:C5567741","GARD:17854","OMIM:616539"],"synonyms":[{"name":"COXPD26","type":"exact"},{"name":"TRMT5 combined oxidative phosphorylation deficiency","type":"exact"},{"name":"combined oxidative phosphorylation deficiency 26","type":"related"},{"name":"combined oxidative phosphorylation deficiency caused by mutation in TRMT5","type":"exact"},{"name":"combined oxidative phosphorylation deficiency type 26","type":"exact"}],"termid":"MONDO:0014684","terms_by_termid":{"MONDO:0014684":null},"xrefs":{"Monarch":{"xref_id":"0014684"}}}


id: GO:0046025
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2 S-adenosyl-L-methionine + precorrin-6Y = 2 S-adenosyl-L-homocysteine + precorrin-8X + CO2.","definition_xrefs":["EC:2.1.1.132"],"direct_ancestors":[{"relation_name":"is_a","term_name":"S-adenosylmethionine-dependent methyltransferase activity","termid":"GO:0008757"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016741","GO:0003824","GO:0016740","GO:0003674"],"is_obsolete":false,"name":"precorrin-6Y C5,15-methyltransferase (decarboxylating) activity","secondary_identifiers":["RHEA:17477","MetaCyc:2.1.1.132-RXN"],"synonyms":[{"name":"S-adenosyl-L-methionine:1-precorrin-6Y C5,15-methyltransferase (C-12-decarboxylating)","type":"related"},{"name":"precorrin-6 methyltransferase activity","type":"broad"},{"name":"precorrin-6Y methylase activity","type":"broad"}],"termid":"GO:0046025"}


id: PBO:0084391
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Low complexity protein; mediates inhibition of Mep1p and Mep3p activity; hyperphosphorylated upon rapamycin treatment in a Tap42p-dependent manner; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; phosphorylation and localization regulated by TORC1-effector kinase, Npr1p","termid":"PBO:0084391"}


id: PBO:0049402
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GUCA1ANB-GUCA1A readthrough","termid":"PBO:0049402"}


id: MONDO:0030708
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An cervicitis (disease) caused by infection with Trichomonas vaginalis.","definition_xrefs":["MONDO:patterns/specific_infectious_disease_by_agent"],"direct_ancestors":[{"relation_name":"is_a","term_name":"trichomoniasis","termid":"MONDO:0002154"},{"relation_name":"is_a","term_name":"cervicitis","termid":"MONDO:0002345"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Trichomonas cervicitis","secondary_identifiers":["MEDGEN:149274","UMLS:C0742232","NCIT:C35588"],"synonyms":[{"name":"Trichomonas cervicitis","type":"exact"},{"name":"Trichomonas vaginalis caused cervicitis (disease)","type":"exact"},{"name":"Trichomonas vaginalis cervicitis (disease)","type":"exact"}],"termid":"MONDO:0030708","xrefs":{"Monarch":{"xref_id":"0030708"}}}


id: PATO:0000278
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000278 hybrid fertility (obsolete PATO:0000278)","termid":"PATO:0000278"}


id: PBO:0074666
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, H/ACA box 52","termid":"PBO:0074666"}


id: GO:0010408
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving the cell wall arabinogalactan II glycoprotein variant which contains both an arabinogalactan protein (AGP) motif and a fasciclin domain.","definition_xrefs":["GOC:tair_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"arabinogalactan protein metabolic process","termid":"GO:0010405"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0071554"}],"interesting_parent_ids":["GO:0071554","GO:0008150"],"is_obsolete":false,"name":"fasciclin-like arabinogalactan protein metabolic process","synonyms":[{"name":"fasciclin-like arabinogalactan protein metabolism","type":"exact"}],"termid":"GO:0010408"}


id: PBO:0087266
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication","termid":"PBO:0087266"}


id: PBO:0064154
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"plakophilin 4 pseudogene 1","termid":"PBO:0064154"}


id: PBO:0027012
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_regulation_of_catalytic_activity","termid":"PBO:0027012"}


id: PBO:0117034
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MACC1 3' UTR overlapping transcript 1","termid":"PBO:0117034"}


id: FYPO:0003994
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of succinate dehydrogenase activity is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal catalytic activity","termid":"FYPO:0000660"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000652"}],"interesting_parent_ids":["FYPO:0000652","FYPO:0000654","FYPO:0000257"],"is_obsolete":false,"name":"normal succinate dehydrogenase activity","termid":"FYPO:0003994"}


id: GO:0002229
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Reactions triggered in response to the presence of oomycetes that act to protect the cell or organism.","definition_xrefs":["GOC:add","PMID:16497589"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to oomycetes","termid":"GO:0002239"},{"relation_name":"is_a","term_name":"defense response","termid":"GO:0006952"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"defense response to oomycetes","termid":"GO:0002229"}


id: GO:0008737
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-fuculose + ATP = L-fuculose 1-phosphate + ADP + 2 H+.","definition_xrefs":["EC:2.7.1.51","RHEA:12376"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphotransferase activity, alcohol group as acceptor","termid":"GO:0016773"},{"relation_name":"is_a","term_name":"carbohydrate kinase activity","termid":"GO:0019200"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016301"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016740","GO:0003824","GO:0003674","GO:0016301"],"is_obsolete":false,"name":"L-fuculokinase activity","secondary_identifiers":["KEGG_REACTION:R03241","MetaCyc:FUCULOKIN-RXN"],"synonyms":[{"name":"ATP:L-fuculose 1-phosphotransferase activity","type":"related"},{"name":"L-fuculokinase (phosphorylating)","type":"related"},{"name":"L-fuculose kinase activity","type":"related"}],"termid":"GO:0008737"}


id: GO:0061245
data:
  {"annotated_genes":["SJAG_01196","SJAG_00661","SJAG_04522","SJAG_04461","SJAG_00845","SJAG_02022","SJAG_01738","SJAG_03705","SJAG_00333","SJAG_03637","SJAG_00236","SJAG_01388","SJAG_00596","SJAG_00514","SJAG_02392","SJAG_00268","SJAG_04703","SJAG_03048","SJAG_03581","SJAG_01799","SJAG_04322","SJAG_00030"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[91682,97664,101463,101557,106478,109444,112712,114160,115903,119766,120519],"is_not":false,"summary":null,"term":"GO:0061245"},{"annotations":[95553,101997,107184],"is_not":false,"rel_names":["positively_regulates","regulates"],"summary":null,"term":"GO:2000247"},{"annotations":[105519],"is_not":false,"rel_names":["regulates","positively_regulates"],"summary":null,"term":"GO:0061361"},{"annotations":[104209],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:2000099"},{"annotations":[97475,96397,106358,92953,114903,120667],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:2000100"}]},"cv_name":"biological_process","definition":"Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns.","definition_xrefs":["GOC:vw","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"establishment or maintenance of cell polarity","termid":"GO:0007163"}],"gene_count":22,"genes_by_uniquename":{"SJAG_00030":null,"SJAG_00236":null,"SJAG_00268":null,"SJAG_00333":null,"SJAG_00514":null,"SJAG_00596":null,"SJAG_00661":null,"SJAG_00845":null,"SJAG_01196":null,"SJAG_01388":null,"SJAG_01738":null,"SJAG_01799":null,"SJAG_02022":null,"SJAG_02392":null,"SJAG_03048":null,"SJAG_03581":null,"SJAG_03637":null,"SJAG_03705":null,"SJAG_04322":null,"SJAG_04461":null,"SJAG_04522":null,"SJAG_04703":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0007163"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0007163"],"is_obsolete":false,"name":"establishment or maintenance of bipolar cell polarity","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0061245","terms_by_termid":{"GO:0061245":null,"GO:0061361":null,"GO:2000099":null,"GO:2000100":null,"GO:2000247":null}}


id: GO:0005496
data:
  {"annotated_genes":["SJAG_01329","SJAG_01407","SJAG_02375","SJAG_04018","SJAG_01590","SJAG_03718","SJAG_02323","SJAG_02982","SJAG_00355","SJAG_00054","SJAG_01722"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[96450],"is_not":false,"summary":null,"term":"GO:0005496"},{"annotations":[74057,110047,96058,113184,118082,72731],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008142"},{"annotations":[78740,63021,64743,92235],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0032934"}]},"cv_name":"molecular_function","definition":"Binding to a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene.","definition_xrefs":["GOC:jl","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lipid binding","termid":"GO:0008289"}],"gene_count":11,"genes_by_uniquename":{"SJAG_00054":null,"SJAG_00355":null,"SJAG_01329":null,"SJAG_01407":null,"SJAG_01590":null,"SJAG_01722":null,"SJAG_02323":null,"SJAG_02375":null,"SJAG_02982":null,"SJAG_03718":null,"SJAG_04018":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008289"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0008289","GO:0005488"],"is_obsolete":false,"name":"steroid binding","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0005496","terms_by_termid":{"GO:0005496":null,"GO:0008142":null,"GO:0032934":null}}


id: MONDO:1010580
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Familial goiter that occurs in golden hamster.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"familial goiter, non-human animal","termid":"MONDO:1010053"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"familial goiter, golden hamster","secondary_identifiers":["OMIA:000424-10036"],"termid":"MONDO:1010580","xrefs":{"Monarch":{"xref_id":"1010580"}}}


id: MONDO:0018077
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Tularemia is an infection caused by the bacterium Francisella tularensis. It is more common in rodents and rabbits but has been found in other animals including domestic cats, sheep, birds, and hamsters. Humans can become infected in several different ways: by handling infected animals, through tick or deer fly bites, by drinking contaminated water, or by inhaling contaminated dust or aerosols. Person-to-person transmission has not been reported. The type of tularemia and the particular signs and symptoms vary depending on how the bacteria enter the body. However, fever is seen in most cases. Though tularemia can be life-threatening, most infections can be treated with antibiotics.","direct_ancestors":[{"relation_name":"is_a","term_name":"primary bacterial infectious disease","termid":"MONDO:0000314"},{"relation_name":"is_a","term_name":"vector-borne disease","termid":"MONDO:0100120"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tularemia","secondary_identifiers":["UMLS:C0041351","EFO:1001444","MedDRA:10045146","GARD:396","ICD10CM:A21","MEDGEN:22520","NCIT:C85208","MESH:D014406","ICD9:021.9","NORD:1803","ICD9:021.8","Orphanet:3392","SCTID:19265001","DOID:2123"],"synonyms":[{"name":"Deerfly fever","type":"related"},{"name":"Francisella tularensis caused disease or disorder","type":"exact"},{"name":"Francisella tularensis disease or disorder","type":"exact"},{"name":"Francisella tularensis infection","type":"related"},{"name":"Francisella tularensis infectious disease","type":"exact"},{"name":"Ohara disease","type":"related"},{"name":"Pahvant Valley plague","type":"related"},{"name":"Yatobyo (Japan)","type":"related"},{"name":"lemming fever","type":"related"},{"name":"rabbit fever","type":"related"}],"termid":"MONDO:0018077","xrefs":{"Monarch":{"xref_id":"0018077"}}}


id: PBO:0004737
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DEP domain protein","termid":"PBO:0004737"}


id: PR:P49731
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A DNA replication licensing factor MCM6 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR11630:SF43","OMA:SCHPO03891","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA replication licensing factor mcm6 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC211.04c","secondary_identifiers":["UniProtKB:P49731"],"synonyms":[{"name":"Spom972h-MCM6","type":"exact"},{"name":"minichromosome maintenance protein 6 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:P49731"}


id: GO:2000085
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis","termid":"GO:2000084"},{"relation_name":"is_a","term_name":"negative regulation of epithelial cell differentiation involved in kidney development","termid":"GO:2000697"},{"relation_name":"negatively_regulates","term_name":"mesenchymal to epithelial transition involved in mesonephros morphogenesis","termid":"GO:0061261"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis","synonyms":[{"name":"negative regulation of mesonephric mesenchyme to epithelial transition","type":"related"}],"termid":"GO:2000085"}


id: MONDO:0018436
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Megakaryoblastic acute myeloid leukemia with t(1;22)(p13;q13) is a rare subtype of acute myeloid leukemia with recurrent cytogenetic abnormalities characterized by clonal proliferation of myeloid blasts with predominantly megakaryoblastic differentiation in the bone marrow and blood, often with extensive infiltration of the abdominal organs. It occurs typically in infants and usually presents with hepatosplenomegaly, anemia, thrombocytopenia and nonspecific symptoms related to ineffective hematopoesis (fatigue, bleeding and bruising, recurrent infections). Myelofibrosis and fibrosis of other infiltrated organs is also characteristic of this disease.","definition_xrefs":["Orphanet:402023"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acute myeloid leukemia","termid":"MONDO:0018874"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0005570","MONDO:0005046"],"is_obsolete":false,"name":"megakaryoblastic acute myeloid leukemia with t(1;22)(p13;q13)","secondary_identifiers":["GARD:21712","UMLS:C4706584","SCTID:763796007","MEDGEN:1638466"],"synonyms":[{"name":"megakaryoblastic AML with t(1;22)(p13;q13)","type":"exact"}],"termid":"MONDO:0018436","xrefs":{"Monarch":{"xref_id":"0018436"}}}


id: PBO:0038632
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acyl-CoA:amino acid N-acyltransferase pseudogene","termid":"PBO:0038632"}


id: PBO:0064779
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein phosphatase, Mg2+/Mn2+ dependent 1A","termid":"PBO:0064779"}


id: FYPO:0000645
data:
  {"alleles_by_uniquename":{"SJAG_02013:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02013","name":"pyp1delta","uniquename":"SJAG_02013:allele-1"},"SJAG_03048:allele-1":{"allele_type":"amino_acid_mutation","description":"G146D","gene_uniquename":"SJAG_03048","name":"cdc2-1w","uniquename":"SJAG_03048:allele-1"},"SJAG_04280:allele-2":{"allele_type":"amino_acid_mutation","description":"T582G","gene_uniquename":"SJAG_04280","name":"wee1-as8","uniquename":"SJAG_04280:allele-2"},"SJAG_04280:allele-3":{"allele_type":"amino_acid_mutation","description":"G788E","gene_uniquename":"SJAG_04280","name":"wee1-G788E","uniquename":"SJAG_04280:allele-3"}},"annotation_feature_type":"genotype","cv_annotations":{"single_locus_phenotype":[{"annotations":[121468,121170,121469,121472],"is_not":false,"rel_names":["is_a","has_part"],"summary":null,"term":"FYPO:0000648"}]},"cv_name":"fission_yeast_phenotype","definition":"A cell morphology phenotype in which a vegetative cell has an abnormally low volume.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"small cell","termid":"FYPO:0000023"},{"relation_name":"is_a","term_name":"abnormal vegetative cell morphology","termid":"FYPO:0001118"}],"gene_count":3,"genes_by_uniquename":{"SJAG_02013":null,"SJAG_03048":null,"SJAG_04280":null},"genotype_count":4,"genotypes_by_uniquename":{"cdc2-1w-G146D-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"cdc2-1w(G146D aa)","display_uniquename":"cdc2-1w-G146D-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_03048:allele-1","expression":"Not assayed or wild type"}]}]},"pyp1delta":{"display_name":"pyp1delta","display_uniquename":"pyp1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02013:allele-1","expression":"Null"}]}]},"wee1-G788E-G788E-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"wee1-G788E(aa)","display_uniquename":"wee1-G788E-G788E-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04280:allele-3","expression":"Not assayed or wild type"}]}]},"wee1-as8-T582G-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"wee1-as8(T582G aa)","display_uniquename":"wee1-as8-T582G-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04280:allele-2","expression":"Not assayed or wild type"}]}]}},"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000005"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000002","FYPO:0001985","FYPO:0000005"],"is_obsolete":false,"name":"small vegetative cell","references_by_uniquename":{"PMID:30664646":null,"PMID:31150379":null},"single_locus_annotated_genes":["SJAG_03048","SJAG_02013","SJAG_04280"],"single_locus_genotype_uniquenames":["pyp1delta","cdc2-1w-G146D-amino_acid_mutation-expression-not_assayed_or_wild_type","wee1-as8-T582G-amino_acid_mutation-expression-not_assayed_or_wild_type","wee1-G788E-G788E-amino_acid_mutation-expression-not_assayed_or_wild_type"],"synonyms":[{"name":"decreased vegetative cell size","type":"exact"},{"name":"reduced vegetative cell size","type":"exact"}],"termid":"FYPO:0000645","terms_by_termid":{"FYECO:0000004":null,"FYECO:0000005":null,"FYECO:0000006":null,"FYECO:0000137":null,"FYECO:0000338":null,"FYPO:0000648":null,"FYPO_EXT:0000001":null,"FYPO_EXT:0000002":null}}


id: FYECO:0000331
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"Experiments were performed in medium containing glucose, salts, water and with arginine as the nitrogen source.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping defined medium","termid":"FYECO:0000013"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glucose MM, arginine nitrogen source","synonyms":[{"name":"glucose minimal medium, arginine nitrogen source","type":"exact"}],"termid":"FYECO:0000331"}


id: PBO:0024473
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sec14 cytosolic factor family, glycerophospholipid-transfer protein Spo20/Sec14","termid":"PBO:0024473"}


id: MONDO:0019526
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Erythema elevatum diutinum (EED) is a distinctive form of chronic cutaneous vasculitis, belonging to the group of the neutrophilic dermatoses.","definition_xrefs":["Orphanet:90000"],"direct_ancestors":[{"relation_name":"is_a","term_name":"immune complex mediated vasculitis","termid":"MONDO:0015491"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"erythema elevatum diutinum","secondary_identifiers":["ICD9:695.89","MEDGEN:75517","SCTID:58872001","DOID:0060567","ICD10CM:L95.1","MESH:C535509","UMLS:C0263398","GARD:8653","icd11.foundation:754210950","MedDRA:10056968"],"termid":"MONDO:0019526","xrefs":{"Monarch":{"xref_id":"0019526"}}}


id: PBO:0071676
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L37 pseudogene 8","termid":"PBO:0071676"}


id: PBO:0028456
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_rate_of_actomyosin_contractile_ring_assembly","termid":"PBO:0028456"}


id: PBO:0051823
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"interferon regulatory factor 2","termid":"PBO:0051823"}


id: PBO:0043683
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cell fate and sterol metabolism associated divergent transcript of MOCOS","termid":"PBO:0043683"}


id: PBO:0054231
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1613","termid":"PBO:0054231"}


id: PBO:0013082
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"does not functionally complement E. coli hisH","termid":"PBO:0013082"}


id: MONDO:0019866
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Mosaic trisomy 5 is a rare chromosomal anomaly syndrome with a variable phenotype ranging from clinically normal to patients presenting intrauterine growth retardation, congenital heart anomalies (mainly ventricular septal defect), multiple dysmorphic features (e.g. hypertelorism, prominent nasal bridge) and other congenital anomalies (incl. eventration of diaphragm, agenesis of corpus callosum, cloverleaf skull, clinodactyly, anteriorly placed anus). Psychomotor development may be normal in spite of low growth parameters being associated.","definition_xrefs":["Orphanet:96060"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chromosome 5 disorder","termid":"MONDO:0700012"},{"relation_name":"is_a","term_name":"trisomy","termid":"MONDO:0700065"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mosaic trisomy 5","secondary_identifiers":["MESH:C537762","GARD:19301","UMLS:C2931603","SCTID:764629008","MEDGEN:419849"],"synonyms":[{"name":"Mosaic trisomy chromosome 5","type":"exact"},{"name":"Mosaic trisomy type 5","type":"exact"},{"name":"trisomy 5 mosaicism","type":"exact"}],"termid":"MONDO:0019866","xrefs":{"Monarch":{"xref_id":"0019866"}}}


id: SO:0000718
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A reading_frame that is interrupted by one or more stop codons; usually identified through inter-genomic sequence comparisons.","definition_xrefs":["SGD:rb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"reading_frame","termid":"SO:0000717"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"blocked_reading_frame","synonyms":[{"name":"blocked reading frame","type":"exact"}],"termid":"SO:0000718"}


id: MONDO:1011350
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Premature aging syndrome that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"non-human animal disease","termid":"MONDO:0005583"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"premature aging syndrome, non-human animal","termid":"MONDO:1011350","xrefs":{"Monarch":{"xref_id":"1011350"}}}


id: GO:0098867
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The increase in size or mass of an intramembranous bone that contributes to the shaping of the bone.","definition_xrefs":["PMID:26399686"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bone growth","termid":"GO:0098868"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"intramembranous bone growth","termid":"GO:0098867"}


id: PBO:0072915
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"scavenger receptor class A member 5","termid":"PBO:0072915"}


id: PBO:0041873
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"calpastatin","termid":"PBO:0041873"}


id: GO:0051587
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that prevents the activation of the directed movement of dopamine into a cell.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of dopamine uptake involved in synaptic transmission","termid":"GO:0051585"},{"relation_name":"is_a","term_name":"inhibition of neurotransmitter uptake","termid":"GO:0051609"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"negatively_regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810"],"is_obsolete":false,"name":"inhibition of dopamine uptake involved in synaptic transmission","synonyms":[{"name":"inhibition of dopamine import involved in synaptic transmission","type":"exact"}],"termid":"GO:0051587"}


id: MONDO:0033092
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive congenital ichthyosis","termid":"MONDO:0017265"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"ichthyosis, congenital, autosomal recessive 13","secondary_identifiers":["DOID:0080257","MEDGEN:1620886","OMIM:617574","UMLS:C4539772"],"synonyms":[{"name":"ARCI13","type":"related"},{"name":"autosomal recessive congenital ichthyosis 13","type":"related"},{"name":"ichthyosis, congenital, autosomal recessive 13","type":"exact"}],"termid":"MONDO:0033092","xrefs":{"Monarch":{"xref_id":"0033092"}}}


id: SO:0002380
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A gene that codes for pseudouridylation_guide_snoRNA. A snoRNA that specifies the site of pseudouridylation in an RNA molecule by base pairing with a short sequence around the target residue.","definition_xrefs":["PMID:12457565"],"direct_ancestors":[{"relation_name":"is_a","term_name":"H_ACA_box_snoRNA_gene","termid":"SO:0002376"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pseudouridylation_guide_snoRNA_gene","synonyms":[{"name":"pseudouridylation guide snoRNA gene","type":"exact"}],"termid":"SO:0002380"}


id: MOD:00904
data:
  {"annotated_genes":["SJAG_00318","SJAG_00331","SJAG_02183","SJAG_01587","SJAG_02498","SJAG_02472"],"annotation_feature_type":"gene","cv_annotations":{"PSI-MOD":[{"annotations":[82431,82441,82366,82345,82425,82286],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MOD:00042"}]},"cv_name":"PSI-MOD","definition":"A protein modification that modifies an L-aspartic acid residue.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein modification categorized by amino acid modified","termid":"MOD:01157"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00318":null,"SJAG_00331":null,"SJAG_01587":null,"SJAG_02183":null,"SJAG_02472":null,"SJAG_02498":null},"genotype_count":0,"is_obsolete":false,"name":"modified L-aspartic acid residue","references_by_uniquename":{"PMID:36408920":null},"synonyms":[{"name":"ModAsp","type":"exact"}],"termid":"MOD:00904","terms_by_termid":{"MOD:00042":null}}


id: GO:0030569
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Stops, prevents or reduces the activity of the serine endopeptidase chymotrypsin.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete chymotrypsin inhibitor activity (obsolete GO:0030569)","synonyms":[{"name":"chymotrypsin inhibitor activity","type":"exact"}],"termid":"GO:0030569"}


id: MONDO:0035448
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. A group of rare central nervous system malformations characterized by varying degrees of absence or dysplasia of the derivatives of the prosencephalon (i. e. telencephalon and diencephalon), with an intact cranial vault. The spectrum comprises atelencephaly, the less severe form, in which only the telencephalon is affected, and aprosencephaly, where the diencephalon is also involved. The malformations may occur in an isolated form or in association with other anomalies. [Orphanet:566847]","definition_xrefs":["Orphanet:566847"],"gene_count":0,"genotype_count":0,"name":"obsolete aprosencephaly/atelencephaly spectrum (obsolete MONDO:0035448)","termid":"MONDO:0035448","xrefs":{"Monarch":{"xref_id":"0035448"}}}


id: PBO:0076679
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcription elongation factor A1 pseudogene 4","termid":"PBO:0076679"}


id: SO:0000499
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A continuous piece of sequence similar to the 'virtual contig' concept of the Ensembl database.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sequence_assembly","termid":"SO:0000353"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"virtual_sequence","synonyms":[{"name":"virtual sequence","type":"exact"}],"termid":"SO:0000499"}


id: GO:0018257
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The modification of peptidyl-lysine to form peptidyl-N6-formyl-L-lysine.","definition_xrefs":["RESID:AA0211"],"gene_count":0,"genotype_count":0,"name":"obsolete peptidyl-lysine formylation (obsolete GO:0018257)","termid":"GO:0018257"}


id: GO:0035774
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.","definition_xrefs":["GOC:bf","GOC:yaf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of insulin secretion","termid":"GO:0032024"},{"relation_name":"is_a","term_name":"regulation of insulin secretion involved in cellular response to glucose stimulus","termid":"GO:0061178"},{"relation_name":"positively_regulates","term_name":"insulin secretion involved in cellular response to glucose stimulus","termid":"GO:0035773"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"positively_regulates","termid":"GO:0023052"},{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0008150","GO:0023052"],"is_obsolete":false,"name":"positive regulation of insulin secretion involved in cellular response to glucose stimulus","synonyms":[{"name":"positive regulation of insulin secretion in response to glucose","type":"exact"}],"termid":"GO:0035774"}


id: PBO:0072268
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S21 pseudogene 6","termid":"PBO:0072268"}


id: MONDO:0002694
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Formation or presence of a blood clot (thrombus) in the cavernous sinus of the brain. Infections of the paranasal sinuses and adjacent structures, craniocerebral trauma, and thrombophilia are associated conditions. Clinical manifestations include dysfunction of cranial nerves iii, iv, V, and vi, marked periorbital swelling, chemosis, fever, and visual loss. (From Adams et al., Principles of Neurology, 6th ed, p711)","definition_xrefs":["MESH:D020226"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracranial sinus thrombosis","termid":"MONDO:0002692"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cavernous sinus thrombosis","secondary_identifiers":["DOID:3575","MEDGEN:65970","SCTID:89980009","UMLS:C0238454"],"synonyms":[{"name":"thrombosis of cavernous venous sinus","type":"exact"}],"termid":"MONDO:0002694","xrefs":{"Monarch":{"xref_id":"0002694"}}}


id: GO:0042954
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Enables the directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells.","definition_xrefs":["GOC:jl","ISBN:0198506732"],"gene_count":0,"genotype_count":0,"name":"obsolete lipoprotein transporter activity (obsolete GO:0042954)","termid":"GO:0042954"}


id: PBO:0079635
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UBE2Q2 pseudogene 6","termid":"PBO:0079635"}


id: GO:1990024
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"Synaptic bouton found in spinal cord on the soma and proximal dendrites of motor neurons.","definition_xrefs":["NIF_Subcellular:nlx_subcell_100208"],"direct_ancestors":[{"relation_name":"is_a","term_name":"terminal bouton","termid":"GO:0043195"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"C bouton","termid":"GO:1990024"}


id: MONDO:0009851
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peripheral neuropathy, ataxia, focal necrotizing encephalopathy, and spongy degeneration of brain","secondary_identifiers":["MEDGEN:342395","MESH:C564894","OMIM:260970","UMLS:C1850022"],"synonyms":[{"name":"peripheral neuropathy, ataxia, focal necrotizing encephalopathy, and spongy degeneration of brain","type":"exact"}],"termid":"MONDO:0009851","xrefs":{"Monarch":{"xref_id":"0009851"}}}


id: MONDO:0015206
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-variable intellectual disability syndrome","termid":"MONDO:0015160"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"short stature-heart defect-craniofacial anomalies syndrome","secondary_identifiers":["MESH:C535871","Orphanet:1088","UMLS:C2931050","MEDGEN:419321"],"synonyms":[{"name":"Rommen Mueller Sybert syndrome","type":"related"},{"name":"Rommen-Mueller-Sybert syndrome","type":"exact"},{"name":"short stature heart defect and craniofacial anomalies","type":"related"}],"termid":"MONDO:0015206","xrefs":{"Monarch":{"xref_id":"0015206"}}}


id: PBO:0040990
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bolA family member 2B","termid":"PBO:0040990"}


id: MONDO:0035423
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"neutral lipid storage disease","termid":"MONDO:0015611"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0002525"},{"rel_name":"is_a","termid":"MONDO:0002561"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0002561","MONDO:0002525"],"is_obsolete":false,"name":"triglyceride deposit cardiomyovasculopathy","secondary_identifiers":["UMLS:C5680124","ICD10CM:E75.5","SCTID:1279844009","Orphanet:565612","GARD:22267","MEDGEN:1830096"],"synonyms":[{"name":"Neutral lipid storage disease with severe cardiovascular involvement","type":"exact"},{"name":"TGCV","type":"exact"}],"termid":"MONDO:0035423","xrefs":{"Monarch":{"xref_id":"0035423"}}}


id: PR:O94269
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- ubp3 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O94269"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin carboxyl-terminal hydrolase 3 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBP8B7.21","synonyms":[{"name":"Spom972h-ubp3","type":"exact"},{"name":"deubiquitinating enzyme 3 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"ubiquitin thioesterase 3 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"ubiquitin-specific-processing protease 3 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O94269"}


id: PBO:0086849
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative regulator of the Fps1p glycerol channel; multiply phosphorylated by Hog1p under osmotic stress; contains a pleckstrin homology domain; forms homodimers and heterodimerizes with paralog Ask10p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm","termid":"PBO:0086849"}


id: GO:0008693
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: (3R)-3-hydroxydecanoyl-[acyl-carrier protein] = 2,3-decenoyl-[acyl-carrier protein] or 3,4-decenoyl-[acyl-carrier protein] + H2O.","definition_xrefs":["PMID:8910376"],"gene_count":0,"genotype_count":0,"name":"obsolete (3R)-3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity (obsolete GO:0008693)","synonyms":[{"name":"(3R)-3-hydroxydecanoyl-acyl-carrier-protein hydro-lyase activity","type":"exact"},{"name":"3-hydroxydecanoyl-ACP dehydratase activity","type":"exact"},{"name":"3-hydroxydecanoyl-[acyl-carrier protein] dehydratase activity","type":"exact"},{"name":"3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity","type":"exact"},{"name":"3-hydroxydecanoyl-acyl carrier protein dehydrase activity","type":"exact"},{"name":"3-hydroxydecanoyl-acyl carrier protein dehydratase activity","type":"exact"},{"name":"3-hydroxydecanoyl-acyl-carrier-protein dehydratase activity","type":"exact"},{"name":"beta-hydroxyacyl-ACP dehydrase activity","type":"exact"},{"name":"beta-hydroxyacyl-acyl carrier protein dehydratase activity","type":"exact"},{"name":"beta-hydroxydecanoate dehydrase activity","type":"exact"},{"name":"beta-hydroxydecanoyl thioester dehydrase activity","type":"exact"}],"termid":"GO:0008693"}


id: PBO:0063388
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"programmed cell death 5 pseudogene 2","termid":"PBO:0063388"}


id: GO:1900581
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of (17Z)-protosta-17(20),24-dien-3beta-ol.","definition_xrefs":["GOC:TermGenie","GOC:di"],"direct_ancestors":[{"relation_name":"is_a","term_name":"steroid biosynthetic process","termid":"GO:0006694"},{"relation_name":"is_a","term_name":"tetracyclic triterpenoid biosynthetic process","termid":"GO:0010686"},{"relation_name":"is_a","term_name":"secondary metabolite biosynthetic process","termid":"GO:0044550"},{"relation_name":"is_a","term_name":"(17Z)-protosta-17(20),24-dien-3beta-ol metabolic process","termid":"GO:1900579"},{"relation_name":"is_a","term_name":"secondary alcohol biosynthetic process","termid":"GO:1902653"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0019748"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0019748","GO:0044281","GO:0008150","GO:0006629"],"is_obsolete":false,"name":"(17Z)-protosta-17(20),24-dien-3beta-ol biosynthetic process","synonyms":[{"name":"(17Z)-protosta-17(20),24-dien-3beta-ol anabolism","type":"exact"},{"name":"(17Z)-protosta-17(20),24-dien-3beta-ol biosynthesis","type":"exact"},{"name":"(17Z)-protosta-17(20),24-dien-3beta-ol formation","type":"exact"},{"name":"(17Z)-protosta-17(20),24-dien-3beta-ol synthesis","type":"exact"}],"termid":"GO:1900581"}


id: PBO:0116618
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lncRNA Wnt/beta-catenin associated regulator","termid":"PBO:0116618"}


id: PBO:0085945
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein of unknown function; non-essential gene; expression induced upon calcium shortage; protein abundance increases in response to DNA replication stress","termid":"PBO:0085945"}


id: GO:1990827
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to an enzyme that catalyzes the removal of an amino group from a substrate, producing ammonia (NH3).","definition_xrefs":["PMID:9792439"],"direct_ancestors":[{"relation_name":"is_a","term_name":"enzyme binding","termid":"GO:0019899"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005488","GO:0005515","GO:0003674"],"is_obsolete":false,"name":"deaminase binding","termid":"GO:1990827"}


id: MONDO:0007328
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"choroidal osteoma, bilateral","secondary_identifiers":["OMIM:118865","UMLS:C1861558","MEDGEN:396164","MESH:C566124"],"synonyms":[{"name":"choroidal osteoma, bilateral","type":"exact"}],"termid":"MONDO:0007328","xrefs":{"Monarch":{"xref_id":"0007328"}}}


