# terms

id: GO:0046932
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ADP + phosphate + Na+(out) => ATP + H2O + Na+(in), by a rotational mechanism.","definition_xrefs":["RHEA:58158"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sodium ion transmembrane transporter activity","termid":"GO:0015081"},{"relation_name":"is_a","term_name":"ligase activity","termid":"GO:0016874"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016874"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0022857","GO:0003674","GO:0005215","GO:0016874"],"is_obsolete":false,"name":"sodium-transporting ATP synthase activity, rotational mechanism","secondary_identifiers":["TC:3.A.2.1.2"],"synonyms":[{"name":"sodium-translocating F-type ATPase activity","type":"exact"},{"name":"sodium-transporting two-sector ATPase activity","type":"exact"}],"termid":"GO:0046932"}


id: PBO:0058884
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 10400","termid":"PBO:0058884"}


id: GO:0030854
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of granulocyte differentiation.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of myeloid leukocyte differentiation","termid":"GO:0002763"},{"relation_name":"is_a","term_name":"regulation of granulocyte differentiation","termid":"GO:0030852"},{"relation_name":"positively_regulates","term_name":"granulocyte differentiation","termid":"GO:0030851"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of granulocyte differentiation","synonyms":[{"name":"activation of granulocyte differentiation","type":"narrow"},{"name":"stimulation of granulocyte differentiation","type":"narrow"},{"name":"up regulation of granulocyte differentiation","type":"exact"},{"name":"up-regulation of granulocyte differentiation","type":"exact"},{"name":"upregulation of granulocyte differentiation","type":"exact"}],"termid":"GO:0030854"}


id: GO:0048770
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes.","definition_xrefs":["GOC:mh","GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytoplasmic vesicle","termid":"GO:0031410"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0031410"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0031410","GO:0005737","GO:0005575"],"is_obsolete":false,"name":"pigment granule","termid":"GO:0048770"}


id: GO:0140180
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"The binding activity of a protein that contributes to the stable formation of a centriole by forming persistent structures, or templates, upon which other centriolar proteins assemble.","definition_xrefs":["PMID:29784964","PMID:32956907","PMID:34702818"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-macromolecule adaptor activity","termid":"GO:0030674"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0060090"},{"rel_name":"is_a","termid":"GO:0030674"}],"interesting_parent_ids":["GO:0030674","GO:0003674","GO:0060090"],"is_obsolete":false,"name":"centriole scaffold activity","termid":"GO:0140180"}


id: FYPO:0001891
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in late meiosis in which the amount of RNA transcribed from middle meiotic genes measured in a cell is higher than normal. Middle meiotic genes are normally transcribed during meiotic nuclear division.","definition_xrefs":["PomBase:mah","PMID:22558440","PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased RNA level during meiotic cell cycle","termid":"FYPO:0005120"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0006551"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0006551","FYPO:0000002","FYPO:0005447"],"is_obsolete":false,"name":"increased level of middle meiotic gene mRNA during late meiosis","synonyms":[{"name":"increased RNA level of middle meiotic genes during late meiosis","type":"exact"},{"name":"increased level of middle meiosis gene mRNA during late meiosis","type":"exact"},{"name":"increased level of middle meiotic gene RNA during late meiosis","type":"exact"},{"name":"increased level of middle meiotic gene RNA during late meiotic nuclear division","type":"exact"},{"name":"increased level of middle meiotic gene transcripts during late meiosis","type":"exact"}],"termid":"FYPO:0001891"}


id: PBO:0051235
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin heavy variable (II)-40-1 (pseudogene)","termid":"PBO:0051235"}


id: PBO:0079273
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tetratricopeptide repeat domain 39D, pseudogene","termid":"PBO:0079273"}


id: GO:0048820
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A developmental process, independent of morphogenetic (shape) change, that is required for a hair follicle to attain its fully functional state.","definition_xrefs":["GOC:devbiol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hair cycle process","termid":"GO:0022405"},{"relation_name":"is_a","term_name":"anatomical structure maturation","termid":"GO:0071695"},{"relation_name":"part_of","term_name":"hair follicle development","termid":"GO:0001942"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"hair follicle maturation","termid":"GO:0048820"}


id: PBO:0049487
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"H1.9 linker histone, pseudogene","termid":"PBO:0049487"}


id: GO:1904191
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any positive regulation of cyclin-dependent protein serine/threonine kinase activity that is involved in meiotic nuclear division.","definition_xrefs":["GO_REF:0000060","PMID:15791259","GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in meiotic nuclear division (obsolete GO:1904191)","synonyms":[{"name":"activation of cyclin-dependent protein kinase activity involved in meiotic nuclear division","type":"narrow"},{"name":"positive regulation of CDK activity involved in meiotic nuclear division","type":"exact"},{"name":"positive regulation of cyclin-dependent protein kinase activity involved in meiosis","type":"broad"},{"name":"stimulation of cyclin-dependent protein kinase activity involved in meiotic nuclear division","type":"narrow"},{"name":"up regulation of cyclin-dependent protein kinase activity involved in meiotic nuclear division","type":"exact"},{"name":"up-regulation of cyclin-dependent protein kinase activity involved in meiotic nuclear division","type":"exact"},{"name":"upregulation of cyclin-dependent protein kinase activity involved in meiotic nuclear division","type":"exact"}],"termid":"GO:1904191"}


id: GO:0060885
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any apoptotic process that contributes to the shaping of the semicircular canal by removing cells in the fusion plate, forming the loops of the canals.","definition_xrefs":["GOC:mtg_apoptosis","GOC:sdb_2009","GOC:tb","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"apoptotic process involved in morphogenesis","termid":"GO:0060561"},{"relation_name":"is_a","term_name":"clearance of cells from fusion plate","termid":"GO:0060884"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"clearance of cells from fusion plate by apoptotic process","synonyms":[{"name":"clearance of cells from fusion plate by apoptosis","type":"narrow"}],"termid":"GO:0060885"}


id: PBO:0069046
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 291, pseudogene","termid":"PBO:0069046"}


id: PBO:0028460
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_galactose-specific_flocculation","termid":"PBO:0028460"}


id: PATO:0002083
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"Having extra or fewer parts.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"has number of","termid":"PATO:0001555"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"altered number of","termid":"PATO:0002083"}


id: GO:0097407
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"Small granular inclusions (about 1-3 microns in diameter) found in the anterior horn cells, and appearing either singly or in a group. Sometimes they are arranged in small beaded chains. Bunina bodies express cystatin C and consist of electron-dense amorphous material that contains tubules or vesicular structures. The amorphous material frequently includes a cytoplasmic island containing neurofilaments and other micro-organelles.","definition_xrefs":["NIF_Subcellular:nlx_subcell_20090101","PMID:18026741"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inclusion body","termid":"GO:0016234"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"Bunina body","termid":"GO:0097407"}


id: GO:1990502
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis.","definition_xrefs":["PMID:22654674","GOC:kmv"],"direct_ancestors":[{"relation_name":"is_a","term_name":"secretory granule maturation","termid":"GO:0061792"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"dense core granule maturation","synonyms":[{"name":"dense core vesicle maturation","type":"exact"}],"termid":"GO:1990502"}


id: PBO:0029990
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_pre-mRNA_level","termid":"PBO:0029990"}


id: GO:0075183
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which an organized mass of hyphae is formed and numerous infective hyphae develop from the hyphae mass.","definition_xrefs":["GOC:pamgo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"formation of infection structure","termid":"GO:0075015"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"infection cushion formation","synonyms":[{"name":"infection cushion formation on or near host","type":"exact"}],"termid":"GO:0075183"}


id: PBO:0077445
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein 178B","termid":"PBO:0077445"}


id: PBO:0004426
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SSU-rRNA maturation protein Tsr4 homolog 1 (predicted)","termid":"PBO:0004426"}


id: PBO:0086765
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative protein of unknown function; shows sequence similarity to FLO1 and other flocculins","termid":"PBO:0086765"}


id: PATO:0020000
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A biological sex quality inhering in an individual based upon genotypic composition of sex chromosomes.","definition_xrefs":["PATOC:MAH"],"direct_ancestors":[{"relation_name":"is_a","term_name":"biological sex","termid":"PATO:0000047"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"genotypic sex","termid":"PATO:0020000"}


id: PBO:0029708
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_cell_population_growth_at_low_pH","termid":"PBO:0029708"}


id: MONDO:0003423
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign, well-circumscribed glandular neoplasm that arises from the middle ear and may exhibit neuroendocrine differentiation. It usually presents with conductive hearing loss.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"adenoma","termid":"MONDO:0004972"},{"relation_name":"is_a","term_name":"benign neoplasm of middle ear","termid":"MONDO:0021482"},{"relation_name":"is_a","term_name":"benign epithelial neoplasm","termid":"MONDO:0036976"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"middle ear adenoma","secondary_identifiers":["NCIT:C6834","SCTID:734078009","DOID:5387"],"synonyms":[{"name":"adenoma of middle ear","type":"related"},{"name":"adenoma of the middle ear","type":"exact"},{"name":"middle ear adenoma","type":"exact"}],"termid":"MONDO:0003423","xrefs":{"Monarch":{"xref_id":"0003423"}}}


id: GO:0070197
data:
  {"annotated_genes":["SJAG_01777","SJAG_01263"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[65551,91579],"is_not":false,"summary":null,"term":"GO:0070197"}]},"cv_name":"biological_process","definition":"The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the nuclear envelope, facilitating bouquet formation.","definition_xrefs":["GOC:pr","GOC:vw","PMID:18818742","GOC:jp"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chromosome attachment to the nuclear envelope","termid":"GO:0097240"},{"relation_name":"is_a","term_name":"meiotic cell cycle process","termid":"GO:1903046"},{"relation_name":"part_of","term_name":"meiotic telomere tethering at nuclear periphery","termid":"GO:0044821"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01263":null,"SJAG_01777":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"part_of","termid":"GO:0140013"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0140013","GO:0051179","GO:0007049","GO:0008150"],"is_obsolete":false,"name":"meiotic attachment of telomere to nuclear envelope","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000107":null},"synonyms":[{"name":"attachment of telomeres to nuclear envelope","type":"broad"},{"name":"attachment of telomeric chromatin to nuclear envelope","type":"broad"}],"termid":"GO:0070197","terms_by_termid":{"GO:0070197":null}}


id: GO:1900413
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of phospholipid biosynthetic process.","definition_xrefs":["GOC:TermGenie","PMID:16537923","GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of phospholipid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter (obsolete GO:1900413)","synonyms":[{"name":"positive regulation of phospholipid biosynthesis by positive regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"positive regulation of phospholipid synthesis by positive regulation of transcription from RNA polymerase II promoter","type":"exact"}],"termid":"GO:1900413"}


id: PBO:0084014
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation; MRK1 has a paralog, RIM11, that arose from the whole genome duplication","termid":"PBO:0084014"}


id: PATO:0000941
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A structural quality inhering in a cytoplasm that contains fluid filled cavities.","definition_xrefs":["PATOC:mh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"structure, cavities","termid":"PATO:0002014"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vacuolated","termid":"PATO:0000941"}


id: MONDO:0006030
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Recurrent infections of the urinary bladder.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cystitis","termid":"MONDO:0006032"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chronic cystitis","secondary_identifiers":["DOID:1680","MEDGEN:65146","SCTID:33655002","EFO:1000023","NCIT:C27008","ICD9:595.2","UMLS:C0221763"],"synonyms":[{"name":"cystitis, chronic","type":"exact"}],"termid":"MONDO:0006030","xrefs":{"Monarch":{"xref_id":"0006030"}}}


id: MONDO:0005350
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Enlargement and ballooning of the vessel that supplies arterial blood to the abdomen, pelvis and legs.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"aortic aneurysm","termid":"MONDO:0005160"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"abdominal aortic aneurysm","secondary_identifiers":["DOID:7693","MEDGEN:56524","icd11.foundation:1154633768","MESH:D017544","UMLS:C0162871","EFO:0004214","SCTID:233985008"],"synonyms":[{"name":"aortic aneurysm, familial abdominal 1","type":"narrow"}],"termid":"MONDO:0005350","xrefs":{"Monarch":{"xref_id":"0005350"}}}


id: GO:2001121
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of a coenzyme gamma-F420-2.","definition_xrefs":["GOC:mengo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"coenzyme gamma-F420-2 metabolic process","termid":"GO:0052649"},{"relation_name":"is_a","term_name":"tricarboxylic acid biosynthetic process","termid":"GO:0072351"},{"relation_name":"is_a","term_name":"organophosphate biosynthetic process","termid":"GO:0090407"},{"relation_name":"is_a","term_name":"carbohydrate derivative biosynthetic process","termid":"GO:1901137"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0044281","GO:0008150"],"is_obsolete":false,"name":"coenzyme gamma-F420-2 biosynthetic process","synonyms":[{"name":"coenzyme gamma-F420-2 biosynthesis","type":"exact"}],"termid":"GO:2001121"}


id: GO:0070035
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: purine NTP + H2O = purine NDP + phosphate, to drive the unwinding of a DNA or RNA helix.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete purine NTP-dependent helicase activity (obsolete GO:0070035)","termid":"GO:0070035"}


id: GO:0034204
data:
  {"annotated_genes":["SJAG_02581","SJAG_02516","SJAG_01731","SJAG_02132","SJAG_02943","SJAG_01945","SJAG_01470","SJAG_00018","SJAG_00589","SJAG_03050","SJAG_00669","SJAG_04734","SJAG_01095","SJAG_02114","SJAG_03209","SJAG_06440","SJAG_02897","SJAG_02957","SJAG_00587","SJAG_00230","SJAG_03774","SJAG_05209","SJAG_00576"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[70233,60480,63674],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140331"},{"annotations":[96236,78798],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034203"},{"annotations":[111357,73807,92331,92334,92335,92329,76276,92333,92328,92330,74699,76520,92336,92332,74792,103100,104032,101286],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0045332"},{"annotations":[74973],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0017121"}]},"cv_name":"biological_process","definition":"The translocation, or flipping, of lipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lipid transport","termid":"GO:0006869"},{"relation_name":"is_a","term_name":"regulation of membrane lipid distribution","termid":"GO:0097035"}],"gene_count":23,"genes_by_uniquename":{"SJAG_00018":null,"SJAG_00230":null,"SJAG_00576":null,"SJAG_00587":null,"SJAG_00589":null,"SJAG_00669":null,"SJAG_01095":null,"SJAG_01470":null,"SJAG_01731":null,"SJAG_01945":null,"SJAG_02114":null,"SJAG_02132":null,"SJAG_02516":null,"SJAG_02581":null,"SJAG_02897":null,"SJAG_02943":null,"SJAG_02957":null,"SJAG_03050":null,"SJAG_03209":null,"SJAG_03774":null,"SJAG_04734":null,"SJAG_05209":null,"SJAG_06440":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0061024"}],"interesting_parent_ids":["GO:0051179","GO:0006810","GO:0061024","GO:0008150"],"is_obsolete":false,"name":"lipid translocation","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null,"GO_REF:0000108":null},"synonyms":[{"name":"intramembrane lipid transfer","type":"exact"}],"termid":"GO:0034204","terms_by_termid":{"GO:0017121":null,"GO:0034203":null,"GO:0045332":null,"GO:0140331":null}}


id: PBO:0003292
data:
  {"annotation_feature_type":"gene","cv_name":"gene_ex","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcriptionally repressed by Srb8","termid":"PBO:0003292"}


id: GO:0005320
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete apolipoprotein (obsolete GO:0005320)","synonyms":[{"name":"apolipoprotein","type":"exact"}],"termid":"GO:0005320"}


id: PBO:0067649
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 824, pseudogene","termid":"PBO:0067649"}


id: GO:0016816
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in substances other than amides, amidines and nitriles.","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in other compounds (obsolete GO:0016816)","synonyms":[{"name":"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in other compounds","type":"exact"}],"termid":"GO:0016816"}


id: FYPO:0003524
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cytoskeleton organization is abnormal at one or both cell tips.","definition_xrefs":["PomBase:mah","GO:0030036","PMID:24954052"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal actin cytoskeleton organization during vegetative growth","termid":"FYPO:0000801"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0004803"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001320","FYPO:0000002","FYPO:0001985","FYPO:0004803"],"is_obsolete":false,"name":"abnormal actin cytoskeleton organization at cell tip","synonyms":[{"name":"abnormal actin cytoskeleton organisation at cell tip","type":"exact"},{"name":"abnormal actin cytoskeleton organization at cell end","type":"exact"},{"name":"abnormal actin cytoskeleton organization at cell tip during mitotic cell cycle","type":"related"},{"name":"abnormal actin cytoskeleton organization at cell tip during vegetative growth","type":"exact"}],"termid":"FYPO:0003524"}


id: PBO:0080772
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"XK related 4","termid":"PBO:0080772"}


id: GO:0009178
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar.","definition_xrefs":["GOC:go_curators","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pyrimidine nucleoside monophosphate catabolic process","termid":"GO:0009131"},{"relation_name":"is_a","term_name":"deoxyribonucleoside monophosphate catabolic process","termid":"GO:0009159"},{"relation_name":"is_a","term_name":"pyrimidine deoxyribonucleoside monophosphate metabolic process","termid":"GO:0009176"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0055086","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"pyrimidine deoxyribonucleoside monophosphate catabolic process","synonyms":[{"name":"pyrimidine deoxyribonucleoside monophosphate breakdown","type":"exact"},{"name":"pyrimidine deoxyribonucleoside monophosphate catabolism","type":"exact"},{"name":"pyrimidine deoxyribonucleoside monophosphate degradation","type":"exact"}],"termid":"GO:0009178"}


id: GO:0036265
data:
  {"annotated_genes":["SJAG_04034","SJAG_02281","SJAG_04680","SJAG_04848"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[60457],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0106005"},{"annotations":[81874],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070476"},{"annotations":[69054,59463],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0106004"}]},"cv_name":"biological_process","definition":"The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an RNA molecule.","definition_xrefs":["GOC:BHF","GOC:rl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA methylation","termid":"GO:0001510"}],"gene_count":4,"genes_by_uniquename":{"SJAG_02281":null,"SJAG_04034":null,"SJAG_04680":null,"SJAG_04848":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"RNA (guanine-N7)-methylation","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000104":null,"GO_REF:0000108":null},"termid":"GO:0036265","terms_by_termid":{"GO:0070476":null,"GO:0106004":null,"GO:0106005":null}}


id: PBO:0063930
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"paired immunoglobin like type 2 receptor alpha","termid":"PBO:0063930"}


id: PBO:0063498
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PDZ and LIM domain 7","termid":"PBO:0063498"}


id: PBO:0048227
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GADD45G interacting protein 1","termid":"PBO:0048227"}


id: MONDO:0010855
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Short tarsus - absence of lower eyelashes is a very rare syndrome characterized by the association of thin and short upper and lower tarsus and absence of the lower eyelashes.","definition_xrefs":["Orphanet:2832"],"direct_ancestors":[{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome without intellectual disability","termid":"MONDO:0015161"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"short tarsus-absence of lower eyelashes syndrome","secondary_identifiers":["GARD:296","MEDGEN:325001","MESH:C537036","OMIM:600269","SCTID:721075001","UMLS:C1838328"],"synonyms":[{"name":"Lopes Gorlin syndrome","type":"related"},{"name":"Lopes-Gorlin syndrome","type":"exact"},{"name":"short tarsus absence of lower eyelashes","type":"related"},{"name":"short tarsus with absence of LOWER eyelashes","type":"related"},{"name":"stale","type":"related"}],"termid":"MONDO:0010855","xrefs":{"Monarch":{"xref_id":"0010855"}}}


id: PBO:0026997
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_DNA_binding_at_PCB","termid":"PBO:0026997"}


id: GO:0044664
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The cellular process of the reversion of cells to their original cell type, occurring as part of the process of phenotypic switching. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns.","definition_xrefs":["GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete reversion of cell type to default state involved in phenotypic switching (obsolete GO:0044664)","termid":"GO:0044664"}


id: PBO:0074993
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, C/D box 115-4","termid":"PBO:0074993"}


id: MONDO:0005725
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A protozoan infection that is caused by Cyclospora cayetanensis, which is most commonly acquired from contaminated food or water, and which is characterized by watery diarrhea and abdominal pain.","definition_xrefs":["NCIT:C128409"],"direct_ancestors":[{"relation_name":"is_a","term_name":"coccidiosis","termid":"MONDO:0005707"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cyclosporiasis","secondary_identifiers":["SCTID:716860005","EFO:0007230","UMLS:C0343398","MEDGEN:91014","GARD:9528","SCTID:240372001","DOID:12750","icd11.foundation:833744511","MESH:D021866","ICD10CM:A07.4","ICD9:007.5","Orphanet:210","ICD10CM:A07.3"],"synonyms":[{"name":"Cyclospora caused disease or disorder","type":"exact"},{"name":"Cyclospora cayetanensis caused disease or disorder","type":"exact"},{"name":"Cyclospora cayetanensis disease or disorder","type":"exact"},{"name":"Cyclospora cayetanensis infectious disease","type":"exact"},{"name":"Cyclospora disease or disorder","type":"exact"},{"name":"Cyclospora infection","type":"related"},{"name":"Cyclospora infectious disease","type":"exact"},{"name":"cyclosporosis","type":"exact"},{"name":"infection of intestine caused by Cyclospora cayetanensis","type":"exact"},{"name":"intestinal infection caused by Cyclospora cayetanensis","type":"exact"}],"termid":"MONDO:0005725","xrefs":{"Monarch":{"xref_id":"0005725"}}}


id: MONDO:1012715
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any difference of sexual development that occurs in domestic cats with a XY karyotype.","definition_xrefs":["OMIA:001601-9685"],"direct_ancestors":[{"relation_name":"is_a","term_name":"difference of sexual differentiation, non-human animal","termid":"MONDO:0700105"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"XY difference of sexual development, domestic cat","termid":"MONDO:1012715","xrefs":{"Monarch":{"xref_id":"1012715"}}}


id: PBO:0060397
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NEDD4 binding protein 2 like 1","termid":"PBO:0060397"}


id: MOD:00838
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively substitutes three (1)H protium atoms with three (2)H deuterium atoms to produce 3x(2)H labeled L-leucine.","definition_xrefs":["Unimod:262#L"],"direct_ancestors":[{"relation_name":"is_a","term_name":"deuterium trisubstituted residue","termid":"MOD:00585"},{"relation_name":"is_a","term_name":"modified L-leucine residue","termid":"MOD:00911"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3x(2)H labeled L-leucine","synonyms":[{"name":"D(H)3Leu","type":"exact"},{"name":"Label:2H(3)","type":"related"},{"name":"Trideuteration","type":"related"}],"termid":"MOD:00838"}


id: PBO:0090040
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Arf GEF Sec73","termid":"PBO:0090040"}


id: MONDO:0025369
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An arbovirus infection of sheep and goats transmitted by ticks. It is characterized by high fever and hemorrhagic gastroenteritis.","definition_xrefs":["MESH:D009265"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sheep disease","termid":"MONDO:0024985"},{"relation_name":"is_a","term_name":"tick-borne infectious disease, non-human animal","termid":"MONDO:0700201"},{"relation_name":"is_a","term_name":"Bunyaviridae infectious disease, non-human animal","termid":"MONDO:0700202"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Nairobi sheep disease","secondary_identifiers":["SCTID:24069003"],"synonyms":[{"name":"disease, Nairobi sheep","type":"related"},{"name":"sheep disease, Nairobi","type":"related"}],"termid":"MONDO:0025369","xrefs":{"Monarch":{"xref_id":"0025369"}}}


id: MONDO:0100626
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An autosomal dominant disorder caused by pathogenic variation in SOX11 characterized by developmental delay, impaired intellectual development and microcephaly. Affected individuals may also have oculomotor apraxia, ocular malformations including coloboma, lens abnormalities and microphthalmia, and hypogonadotropic hypogonadism. Some patients may have finger clinodactyly and hypoplastic distal phalanges with nail hypoplasia, especially of the fifth digits. Individuals with variants in SOX11 have a \\\"unique peripheral blood DNA methylation signature as a diagnostic biomarker and phenotypic clustering analysis that distinguishes SOX11 syndrome from BAFopathies.","definition_xrefs":["PMID:35341651"],"direct_ancestors":[{"relation_name":"is_a","term_name":"complex neurodevelopmental disorder with or without congenital anomalies","termid":"MONDO:0100465"},{"relation_name":"is_a","term_name":"Mendelian neurodevelopmental disorder","termid":"MONDO:0100500"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0700092"}],"interesting_parent_ids":["MONDO:0700092"],"is_obsolete":false,"name":"SOX11-related complex neurodevelopmental disorder with or without congenital anomalies","synonyms":[{"name":"intellectual developmental disorder with microcephaly and with or without ocular malformations or hypogonadotropic hypogonadism","type":"narrow"}],"termid":"MONDO:0100626","xrefs":{"Monarch":{"xref_id":"0100626"}}}


id: GO:0045015
data:
  {"annotated_genes":["SJAG_02418"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[115489],"is_not":false,"summary":null,"term":"GO:0045015"}]},"cv_name":"molecular_function","definition":"Binding to a HDEL sequence, the C terminus tetrapeptide sequence His-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum.","definition_xrefs":["PMID:1327759"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ER retention sequence binding","termid":"GO:0046923"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02418":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005048"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0005488","GO:0005048","GO:0003674"],"is_obsolete":false,"name":"HDEL sequence binding","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"HDEL receptor activity","type":"narrow"}],"termid":"GO:0045015","terms_by_termid":{"GO:0045015":null}}


id: PBO:0063547
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peroxisomal trans-2-enoyl-CoA reductase","termid":"PBO:0063547"}


id: SO:0001952
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A region immediately adjacent to a promoter which may or may not contain transcription factor binding sites.","definition_xrefs":["EBI:nj"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transcriptional_cis_regulatory_region","termid":"SO:0001055"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"promoter_flanking_region","synonyms":[{"name":"promoter flanking region","type":"exact"}],"termid":"SO:0001952"}


id: GO:0002859
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of natural killer cell mediated immune response to tumor cell","termid":"GO:0002856"},{"relation_name":"is_a","term_name":"regulation of natural killer cell mediated cytotoxicity directed against tumor cell target","termid":"GO:0002858"},{"relation_name":"is_a","term_name":"negative regulation of natural killer cell mediated cytotoxicity","termid":"GO:0045953"},{"relation_name":"negatively_regulates","term_name":"natural killer cell mediated cytotoxicity directed against tumor cell target","termid":"GO:0002420"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target","synonyms":[{"name":"down regulation of natural killer cell mediated cytotoxicity directed against tumor cell target","type":"exact"},{"name":"down-regulation of natural killer cell mediated cytotoxicity directed against tumor cell target","type":"exact"},{"name":"downregulation of natural killer cell mediated cytotoxicity directed against tumor cell target","type":"exact"},{"name":"inhibition of natural killer cell mediated cytotoxicity directed against tumor cell target","type":"narrow"}],"termid":"GO:0002859"}


id: PBO:0028155
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_epirubicin","termid":"PBO:0028155"}


id: PBO:0067717
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal 15","termid":"PBO:0067717"}


id: FYECO:0000153
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which diethyl maleate was added to the medium or assay buffer in excess compared to standard medium or assay buffers.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping excess","termid":"FYECO:0000109"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ diethyl maleate","synonyms":[{"name":"diethyl maleate added","type":"exact"}],"termid":"FYECO:0000153"}


id: MONDO:0017933
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hypertrophic cardiomyopathy and renal tubular disease due to mitochondrial DNA mutation is a mitochondrial oxidative phosphorylation disorder characterized by hypertrophic and dilated cardiomyopathy, failure to thrive, myopathy with generalized hypotonia and increased creatine kinase, developmental delay and/or regression with cerebral atrophy on brain MRI, renal manifestations including chronic renal failure, renal tubular acidosis and lactic acidosis. Additional clinical features include seizures and respiratory failure.","definition_xrefs":["Orphanet:324525"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mitochondrial oxidative phosphorylation disorder","termid":"MONDO:0016387"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0004069","MONDO:0005066"],"is_obsolete":false,"name":"hypertrophic cardiomyopathy and renal tubular disease due to mitochondrial DNA mutation","secondary_identifiers":["MEDGEN:1650300","UMLS:C4749942","GARD:21442"],"synonyms":[{"name":"hypertrophic cardiomyopathy and renal tubular disease due to mtDNA mutation","type":"exact"}],"termid":"MONDO:0017933","xrefs":{"Monarch":{"xref_id":"0017933"}}}


id: MONDO:0005419
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A drug dependence that is a psychological dependency on the regular use of methamphetamine.","definition_xrefs":["EFO:0004701"],"direct_ancestors":[{"relation_name":"is_a","term_name":"drug dependence","termid":"MONDO:0005303"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"methamphetamine dependence","secondary_identifiers":["MEDGEN:735816","UMLS:C1533217"],"termid":"MONDO:0005419","xrefs":{"Monarch":{"xref_id":"0005419"}}}


id: MONDO:0020406
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"complete atrioventricular canal","termid":"MONDO:0015273"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"complete atrioventricular canal-left heart obstruction syndrome","secondary_identifiers":["Orphanet:99066"],"synonyms":[{"name":"CAVC type A","type":"exact"},{"name":"CAVC-left heart obstruction syndrome","type":"exact"},{"name":"complete atrioventricular canal type A","type":"exact"}],"termid":"MONDO:0020406","xrefs":{"Monarch":{"xref_id":"0020406"}}}


id: PBO:0076760
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TDH antisense RNA 1","termid":"PBO:0076760"}


id: GO:0036039
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving the polyphenol, curcumin.","definition_xrefs":["PMID:21467222"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ether metabolic process","termid":"GO:0018904"},{"relation_name":"is_a","term_name":"phenol-containing compound metabolic process","termid":"GO:0018958"},{"relation_name":"is_a","term_name":"ketone metabolic process","termid":"GO:0042180"},{"relation_name":"is_a","term_name":"olefinic compound metabolic process","termid":"GO:0120254"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0044281","GO:0008150"],"is_obsolete":false,"name":"curcumin metabolic process","synonyms":[{"name":"(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione metabolic process","type":"exact"},{"name":"(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione metabolism","type":"exact"},{"name":"curcumin metabolism","type":"exact"},{"name":"diferuloylmethane metabolic process","type":"exact"},{"name":"diferuloylmethane metabolism","type":"exact"},{"name":"turmeric yellow metabolic process","type":"exact"},{"name":"turmeric yellow metabolism","type":"exact"}],"termid":"GO:0036039"}


id: GO:0002573
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage.","definition_xrefs":["GOC:add","PMID:16551251"],"direct_ancestors":[{"relation_name":"is_a","term_name":"leukocyte differentiation","termid":"GO:0002521"},{"relation_name":"is_a","term_name":"myeloid cell differentiation","termid":"GO:0030099"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"myeloid leukocyte differentiation","synonyms":[{"name":"myeloid leucocyte differentiation","type":"exact"}],"termid":"GO:0002573"}


id: PBO:0113244
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Nuclease required for DNA single- and double-strand break repair; acts at a post-incision step in repair of breaks that result from interstrand cross-links produced by a variety of mono- and bi-functional psoralen derivatives; induced by UV-irradiation; forms nuclear foci upon DNA replication stress; translocates to mitochondria under genotoxic agents","termid":"PBO:0113244"}


id: FYPO:0003916
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the degradation of messenger RNA (mRNA) molecules that contain nonsense mutations is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gene expression regulation phenotype during vegetative growth","termid":"FYPO:0001333"},{"relation_name":"is_a","term_name":"abnormal RNA catabolic process during vegetative growth","termid":"FYPO:0002136"},{"relation_name":"is_a","term_name":"abnormal gene expression","termid":"FYPO:0006551"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000294"}],"interesting_parent_ids":["FYPO:0000294","FYPO:0001320","FYPO:0001985","FYPO:0006551","FYPO:0000002","FYPO:0005447"],"is_obsolete":false,"name":"abnormal nonsense-mediated decay","synonyms":[{"name":"abnormal NMD","type":"exact"},{"name":"abnormal nonsense-mediated decay during mitotic cell cycle","type":"related"},{"name":"abnormal nonsense-mediated decay during vegetative growth","type":"exact"},{"name":"abnormal nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","type":"exact"}],"termid":"FYPO:0003916"}


id: PBO:0058474
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 5582","termid":"PBO:0058474"}


id: PBO:0028961
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_glycoprotein_glycan_structure","termid":"PBO:0028961"}


id: PBO:0066463
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"replication factor C subunit 1","termid":"PBO:0066463"}


id: GO:1990622
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A heterodimeric protein complex that is composed of CHOP (C/EBP homology protein, GADD153) and ATF3 (activating transcription factor 3) subunits.","definition_xrefs":["GOC:PARL","PMID:8622660","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transcription regulator complex","termid":"GO:0005667"},{"relation_name":"is_a","term_name":"nuclear protein-containing complex","termid":"GO:0140513"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005634"}],"interesting_parent_ids":["GO:0032991","GO:0005634","GO:0005575"],"is_obsolete":false,"name":"CHOP-ATF3 complex","synonyms":[{"name":"ATF3-CHOP complex","type":"exact"},{"name":"CHOP-ATF3 heterodimer","type":"exact"},{"name":"CHOP-ATF3 heterodimeric complex","type":"exact"},{"name":"GADD153-ATF3 complex","type":"exact"}],"termid":"GO:1990622"}


id: GO:1902286
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any semaphorin-plexin signaling pathway that is involved in dendrite guidance.","definition_xrefs":["PMID:22790009","GOC:TermGenie","GOC:rl","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"semaphorin-plexin signaling pathway involved in neuron projection guidance","termid":"GO:1902285"},{"relation_name":"part_of","term_name":"dendrite guidance","termid":"GO:0070983"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"semaphorin-plexin signaling pathway involved in dendrite guidance","synonyms":[{"name":"semaphorin-plexin signaling pathway involved in dendritic guidance","type":"exact"},{"name":"semaphorin-plexin signalling pathway involved in dendrite guidance","type":"exact"},{"name":"semaphorin-plexin signalling pathway involved in dendritic guidance","type":"exact"}],"termid":"GO:1902286"}


id: MONDO:0010447
data:
  {"annotated_genes":["SJAG_01047"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88707],"is_not":false,"summary":null,"term":"MONDO:0010447"}]},"cv_name":"mondo","definition":"Any non-syndromic X-linked intellectual disability in which the cause of the disease is a mutation in the RPS6KA3 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"non-syndromic X-linked intellectual disability","termid":"MONDO:0019181"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01047":null},"genotype_count":0,"is_obsolete":false,"name":"intellectual disability, X-linked 19","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:300844","MEDGEN:208676","GARD:22687","MESH:C563141","UMLS:C0796225","DOID:0112019"],"synonyms":[{"name":"MRX19","type":"related"},{"name":"RPS6KA3 non-syndromic X-linked intellectual disability","type":"exact"},{"name":"intellectual developmental disorder, X-linked 19, X-linked dominant","type":"exact"},{"name":"intellectual disability, X-linked 19","type":"exact"},{"name":"intellectual disability, X-linked type 19","type":"exact"},{"name":"mental retardation, X-linked 19","type":"related"},{"name":"mental retardation, X-linked type 19","type":"exact"},{"name":"non-syndromic X-linked intellectual disability caused by mutation in RPS6KA3","type":"exact"}],"termid":"MONDO:0010447","terms_by_termid":{"MONDO:0010447":null},"xrefs":{"Monarch":{"xref_id":"0010447"}}}


id: GO:0070006
data:
  {"annotated_genes":["SJAG_03744","SJAG_03022","SJAG_06636","SJAG_01896","SJAG_02033","SJAG_00969","SJAG_01088","SJAG_00181"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[57978,60678,64808,65601,74382,76213,99655,116312],"is_not":false,"summary":null,"term":"GO:0070006"}]},"cv_name":"molecular_function","definition":"Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.","direct_ancestors":[{"relation_name":"is_a","term_name":"aminopeptidase activity","termid":"GO:0004177"},{"relation_name":"is_a","term_name":"metalloexopeptidase activity","termid":"GO:0008235"}],"gene_count":8,"genes_by_uniquename":{"SJAG_00181":null,"SJAG_00969":null,"SJAG_01088":null,"SJAG_01896":null,"SJAG_02033":null,"SJAG_03022":null,"SJAG_03744":null,"SJAG_06636":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008233"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0140096","GO:0003824","GO:0003674","GO:0008233","GO:0016787"],"is_obsolete":false,"name":"metalloaminopeptidase activity","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0070006","terms_by_termid":{"GO:0070006":null}}


id: PBO:0054640
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2045","termid":"PBO:0054640"}


id: MONDO:0007644
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Decreased or absent levels of serum immunoglobulin A, with normal serum levels of immunoglobulin G and immunoglobulin M in a patient who is older than 4 years of age and in whom all other causes of hypogammaglobulinemia have been excluded. Affected individuals may be asymptomatic or have frequent infections, allergic reactions, or autoimmune disorders.","definition_xrefs":["NCIT:C123434"],"direct_ancestors":[{"relation_name":"is_a","term_name":"selective IgA deficiency disease","termid":"MONDO:0001341"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0005046"],"is_obsolete":false,"name":"IgAD1","secondary_identifiers":["MESH:C536290","OMIM:137100","MEDGEN:419725","UMLS:C2931161"],"synonyms":[{"name":"IGAD1","type":"exact"},{"name":"IMMUNOGLOBULIN A deficiency 1","type":"related"},{"name":"IgA, selective deficiency of","type":"related"},{"name":"IgAD1","type":"exact"},{"name":"Immunoglobulin A, selective deficiency of","type":"related"},{"name":"gamma-A-globulin, selective deficiency of","type":"related"},{"name":"immunoglobulin A deficiency, autosomal recessive, autosomal dominant, isolated cases","type":"exact"}],"termid":"MONDO:0007644","xrefs":{"Monarch":{"xref_id":"0007644"}}}


id: MOD:01741
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces an O3-hydrogen atom of a serine residue with the Proteome Sciences TMT6plex-128 reporter+balance group.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"TMT6plex reporter+balance reagent O-acylated residue","termid":"MOD:01719"},{"relation_name":"is_a","term_name":"TMT6plex-128 reporter+balance reagent acylated residue","termid":"MOD:01736"},{"relation_name":"is_a","term_name":"O3-acylated L-serine","termid":"MOD:02003"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TMT6plex-128 reporter+balance reagent O3-acylated serine","synonyms":[{"name":"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl","type":"exact"},{"name":"Sixplex Tandem Mass Tag(TM)","type":"related"},{"name":"TMT6plex","type":"related"}],"termid":"MOD:01741"}


id: PBO:0031482
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_cellular_pigment_accumulation","termid":"PBO:0031482"}


id: PBO:0051423
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin lambda variable 2-34 (pseudogene)","termid":"PBO:0051423"}


id: SO:0000681
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A transcript that has been processed \\\"incorrectly\\\", for example by the failure of splicing of one or more exons.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transcript","termid":"SO:0000673"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aberrant_processed_transcript","synonyms":[{"name":"aberrant processed transcript","type":"exact"}],"termid":"SO:0000681"}


id: PBO:0057756
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 1915","termid":"PBO:0057756"}


id: GO:0050783
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tropane alkaloid metabolic process","termid":"GO:0046448"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cocaine metabolic process","synonyms":[{"name":"cocaine metabolism","type":"exact"}],"termid":"GO:0050783"}


id: MONDO:0009960
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any inflammatory bowel disease in which the cause of the disease is a mutation in the NOD2 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inflammatory bowel disease","termid":"MONDO:0005265"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0004335"],"is_obsolete":false,"name":"inflammatory bowel disease 1","secondary_identifiers":["DOID:0110892","SCTID:34000006","ICD9:555.9","OMIM:266600"],"synonyms":[{"name":"Crohn disease","type":"related"},{"name":"Crohn disease-associated growth failure","type":"exact"},{"name":"Crohn disease-associated growth failure, susceptibility to","type":"related"},{"name":"IBD1","type":"exact"},{"name":"NOD2 inflammatory bowel disease","type":"exact"},{"name":"inflammatory bowel disease (Crohn disease) 1","type":"exact"},{"name":"inflammatory bowel disease 1","type":"exact"},{"name":"inflammatory bowel disease 1, Crohn disease","type":"exact"},{"name":"inflammatory bowel disease caused by mutation in NOD2","type":"exact"},{"name":"inflammatory bowel disease type 1","type":"exact"},{"name":"paediatric ulcerative colitis","type":"related"},{"name":"pediatric ulcerative colitis","type":"related"},{"name":"regional enteritis","type":"related"},{"name":"ulcerative colitis","type":"related"},{"name":"ulcerative colitis, paediatric","type":"related"},{"name":"ulcerative colitis, pediatric","type":"related"}],"termid":"MONDO:0009960","xrefs":{"Monarch":{"xref_id":"0009960"}}}


id: PBO:0059468
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mutS homolog 6","termid":"PBO:0059468"}


id: PBO:0043423
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cyclic nucleotide gated channel subunit alpha 1","termid":"PBO:0043423"}


id: PATO:0001512
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A pattern inhering in a surface by virtue of the bearer's being marked by the presence of dots, punctures, points or pits.","definition_xrefs":["medical-dictionary:medical-dictionary"],"direct_ancestors":[{"relation_name":"is_a","term_name":"irregular spatial pattern","termid":"PATO:0000330"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"punctate","synonyms":[{"name":"dotted","type":"related"},{"name":"spotted","type":"related"},{"name":"stippled","type":"related"}],"termid":"PATO:0001512"}


id: GO:0009307
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A defense process found in many bacteria and archaea that protects the organism from invading foreign DNA by cleaving it with a restriction endonuclease. The organism's own DNA is protected by methylation of a specific nucleotide, which occurs immediately following replication, in the same target site as the restriction enzyme.","definition_xrefs":["GOC:jl","UniProtKB-KW:KW-0680"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA modification","termid":"GO:0006304"},{"relation_name":"is_a","term_name":"clearance of foreign intracellular DNA","termid":"GO:0044355"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006259"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006259","GO:0008150"],"is_obsolete":false,"name":"DNA restriction-modification system","synonyms":[{"name":"DNA restriction","type":"broad"}],"termid":"GO:0009307"}


id: MONDO:0022551
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A polygenic and multifactorial disease that develops as a result of a complex interplay between genetic susceptibility and environmental and endogenous factors, which leads to the loss of immune tolerance to thyroid antigens and in particular to the TSH receptor.","definition_xrefs":["PMID:26293122"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Basedow's coma","synonyms":[{"name":"Coma basedovicum","type":"related"},{"name":"Karl Adolph von Basedow","type":"related"}],"termid":"MONDO:0022551","xrefs":{"Monarch":{"xref_id":"0022551"}}}


id: GO:0019142
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: glyoxylate + H2O + propanoyl-CoA = 2-hydroxyglutarate + CoA + H+.","definition_xrefs":["RHEA:19185"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acyltransferase activity, acyl groups converted into alkyl on transfer","termid":"GO:0046912"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0016740","GO:0003824","GO:0016746","GO:0003674"],"is_obsolete":false,"name":"2-hydroxyglutarate synthase activity","secondary_identifiers":["KEGG_REACTION:R00932","MetaCyc:HYDGLUTSYN-RXN","EC:2.3.3.11"],"synonyms":[{"name":"2-hydroxyglutarate glyoxylate-lyase (CoA-propanoylating) activity","type":"related"},{"name":"2-hydroxyglutaratic synthetase activity","type":"related"},{"name":"2-hydroxyglutaric synthetase activity","type":"related"},{"name":"alpha-hydroxyglutarate synthase activity","type":"related"},{"name":"hydroxyglutarate synthase activity","type":"related"},{"name":"propanoyl-CoA:glyoxylate C-propanoyltransferase (thioester-hydrolysing, 2-carboxyethyl-forming)","type":"related"}],"termid":"GO:0019142"}


id: PBO:0068246
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 28S ribosomal 3","termid":"PBO:0068246"}


id: GO:0002675
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of acute inflammatory response","termid":"GO:0002673"},{"relation_name":"is_a","term_name":"positive regulation of inflammatory response","termid":"GO:0050729"},{"relation_name":"positively_regulates","term_name":"acute inflammatory response","termid":"GO:0002526"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of acute inflammatory response","synonyms":[{"name":"activation of acute inflammatory response","type":"narrow"},{"name":"stimulation of acute inflammatory response","type":"narrow"},{"name":"up regulation of acute inflammatory response","type":"exact"},{"name":"up-regulation of acute inflammatory response","type":"exact"},{"name":"upregulation of acute inflammatory response","type":"exact"}],"termid":"GO:0002675"}


id: GO:1904235
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate.","definition_xrefs":["PMID:25834989","GO_REF:0000058","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cell-substrate adhesion","termid":"GO:0010810"},{"relation_name":"is_a","term_name":"regulation of cell migration","termid":"GO:0030334"},{"relation_name":"regulates","term_name":"substrate-dependent cell migration, cell attachment to substrate","termid":"GO:0006931"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0007155"}],"interesting_parent_ids":["GO:0007155","GO:0008150"],"is_obsolete":false,"name":"regulation of substrate-dependent cell migration, cell attachment to substrate","synonyms":[{"name":"regulation of substrate-bound cell migration, cell attachment to substrate","type":"exact"}],"termid":"GO:1904235"}


id: GO:0044151
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The increase in size or mass of an organism occurring on or near the exterior of its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:cc","GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete growth of host on or near symbiont surface (obsolete GO:0044151)","synonyms":[{"name":"growth of organism on or near symbiont surface","type":"exact"}],"termid":"GO:0044151"}


id: PATO:0000926
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000926 intercross fertility (obsolete PATO:0000926)","termid":"PATO:0000926"}


id: FYPO:0004789
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which telomeres have fused, forming circular chromosomes, during G2 phase of the mitotic cell cycle.","definition_xrefs":["PomBase:mah","PMID:25533340"],"direct_ancestors":[{"relation_name":"is_a","term_name":"circularized chromosome","termid":"FYPO:0002702"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0000641"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"output_of","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000654","FYPO:0000661","FYPO:0001320","FYPO:0000002","FYPO:0000707","FYPO:0000641","FYPO:0005447","FYPO:0000652"],"is_obsolete":false,"name":"circularized chromosome during mitotic G2 phase","synonyms":[{"name":"circular chromosomes during mitotic G2 phase","type":"exact"},{"name":"circularised chromosome during mitotic G2 phase","type":"exact"},{"name":"circularized chromosome during G2 during vegetative growth","type":"exact"},{"name":"fused telomeres during mitotic G2 phase","type":"related"},{"name":"telomere end fusion during mitotic G2 phase","type":"related"},{"name":"telomere fusion during mitotic G2 phase","type":"related"},{"name":"telomeres fused during mitotic G2 phase","type":"related"}],"termid":"FYPO:0004789"}


id: PBO:0001590
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"LAlv9 family protein, involved in post Golgi transport (predicted)","termid":"PBO:0001590"}


id: RO:0002377
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"x distributary_of y if and only if x is capable of channeling the flow of a substance to y, where y channels less of the substance than x","direct_ancestors":[{"relation_name":"is_a","term_name":"in_branching_relationship_with","termid":"RO:0002375"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"distributary_of","termid":"RO:0002377"}


id: PBO:0084577
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Merged open reading frame; does not encode a discrete protein; YAR044W was originally annotated as an independent ORF, but as a result of a sequence change, it was merged with an adjacent ORF into a single reading frame, designated YAR042W","termid":"PBO:0084577"}


id: MONDO:1010559
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Spina bifida that occurs in sheep.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"spina bifida, non-human animal","termid":"MONDO:1010047"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spina bifida, sheep","secondary_identifiers":["OMIA:000933-9940"],"termid":"MONDO:1010559","xrefs":{"Monarch":{"xref_id":"1010559"}}}


id: MONDO:0011906
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Congenital bile acid synthesis defect type 1 (BAS defect type 1) is the most common anomaly of bile acid synthesis characterized by variable manifestations of progressive cholestatic liver disease, and fat malabsorption.","definition_xrefs":["Orphanet:79301"],"direct_ancestors":[{"relation_name":"is_a","term_name":"congenital bile acid synthesis defect","termid":"MONDO:0018841"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002525"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0002525","MONDO:0005066"],"is_obsolete":false,"name":"congenital bile acid synthesis defect 1","secondary_identifiers":["GARD:9813","DOID:0111071","MEDGEN:335883","MESH:C535442","OMIM:607765","UMLS:C1843116"],"synonyms":[{"name":"3-Beta-hydroxy-Delta-5-C27-steroid oxidoreductase deficiency","type":"related"},{"name":"3-alpha beta-hydroxy-delta-5-C27-steroid oxidoreductase, deficiency of","type":"related"},{"name":"3-beta-hydroxy-delta-5-C27-steroid oxidoreductase deficiency type 1","type":"exact"},{"name":"BASD1","type":"exact"},{"name":"CBAS1","type":"exact"},{"name":"HSD3B7 congenital bile acid synthesis defect","type":"exact"},{"name":"bile acid synthesis defect, congenital, 1","type":"related"},{"name":"bile acid synthesis defect, congenital, type 1","type":"exact"},{"name":"congenital bile acid synthesis defect 1","type":"exact"},{"name":"congenital bile acid synthesis defect caused by mutation in HSD3B7","type":"exact"},{"name":"congenital bile acid synthesis defect type 1","type":"exact"},{"name":"congenital bile acid synthesis defect, type 1","type":"related"}],"termid":"MONDO:0011906","xrefs":{"Monarch":{"xref_id":"0011906"}}}


id: GO:0038074
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that contributes to conjugation with cellular fusion.","definition_xrefs":["GOC:signaling"],"gene_count":0,"genotype_count":0,"name":"obsolete MAP kinase phosphatase activity involved in regulation of conjugation with cellular fusion (obsolete GO:0038074)","synonyms":[{"name":"MAPK phosphatase activity involved in regulation of conjugation with cellular fusion","type":"exact"}],"termid":"GO:0038074"}


id: PBO:0044124
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CTAGE family member 10, pseudogene","termid":"PBO:0044124"}


id: PBO:0003776
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial PPR repeat protein Ppr2","termid":"PBO:0003776"}


id: FYPO:0001810
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of guanine into the cell occurs to a lower extent than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal guanine import","termid":"FYPO:0001809"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000138"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000138","FYPO:0001985","FYPO:0000002","FYPO:0005447"],"is_obsolete":false,"name":"decreased guanine import","synonyms":[{"name":"decreased guanine import across plasma membrane","type":"exact"},{"name":"decreased guanine import during mitotic cell cycle","type":"related"},{"name":"decreased guanine import during vegetative growth","type":"exact"},{"name":"decreased guanine import into cell","type":"exact"},{"name":"decreased guanine uptake","type":"exact"},{"name":"reduced guanine import","type":"exact"}],"termid":"FYPO:0001810"}


id: GO:0071869
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution.","definition_xrefs":["GOC:mah","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to monoamine","termid":"GO:0071867"},{"relation_name":"is_a","term_name":"response to oxygen-containing compound","termid":"GO:1901700"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to catecholamine","synonyms":[{"name":"response to catecholamine stimulus","type":"exact"}],"termid":"GO:0071869"}


id: PBO:0031243
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_DNA_repair_during_vegetative_growth","termid":"PBO:0031243"}


id: PBO:0088185
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Zinc-finger DNA-binding transcription factor; targets strong transcriptional activator Met4p to promoters of sulfur metabolic genes; involved in transcriptional regulation of the methionine biosynthetic genes; feedforward loop controlling expression of MET32 and the lack of such a loop for MET31 may account for the differential actions of Met31p and Met32p; MET31 has a paralog, MET32, that arose from the whole genome duplication","termid":"PBO:0088185"}


id: PBO:0004527
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"linear element associated protein Hop1","termid":"PBO:0004527"}


id: GO:1990151
data:
  {"annotated_genes":["SJAG_01196","SJAG_03011","SJAG_01373","SJAG_00851","SJAG_03915","SJAG_02392"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[92774,97669],"is_not":false,"rel_names":["regulates","negatively_regulates"],"summary":null,"term":"GO:1903067"},{"annotations":[115904,118039,93108],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990896"},{"annotations":[105566],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0099117"}]},"cv_name":"biological_process","definition":"A process in which a protein is transported to, or maintained in, a location at the cell tip.","definition_xrefs":["PMID:22768263"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracellular protein localization","termid":"GO:0008104"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00851":null,"SJAG_01196":null,"SJAG_01373":null,"SJAG_02392":null,"SJAG_03011":null,"SJAG_03915":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0051179"],"is_obsolete":false,"name":"protein localization to cell tip","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"protein localisation to cell tip","type":"exact"}],"termid":"GO:1990151","terms_by_termid":{"GO:0099117":null,"GO:1903067":null,"GO:1990896":null}}


id: GO:0002777
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of an antimicrobial peptide. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.","definition_xrefs":["PMID:11807545","PMID:15638771","ISBN:0781735149","GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"peptide biosynthetic process","termid":"GO:0043043"},{"relation_name":"part_of","term_name":"antimicrobial peptide production","termid":"GO:0002775"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"antimicrobial peptide biosynthetic process","termid":"GO:0002777"}


id: MONDO:1011736
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"integumentary system disorder, non-human animal","termid":"MONDO:1011328"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dermatosis vegetans, non-human animal","secondary_identifiers":["OMIA:000271"],"termid":"MONDO:1011736","xrefs":{"Monarch":{"xref_id":"1011736"}}}


id: PR:Q9P7M6
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAP27G11.12 gene.","definition_xrefs":["UniProtKB:Q9P7M6","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Hid-1 family protein P27G11.12 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAP27G11.12","synonyms":[{"name":"Down-regulated in multiple cancers 1 homolog 1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-SPAP27G11.12","type":"exact"}],"termid":"PR:Q9P7M6"}


id: GO:0034947
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: terephthalate + H2O = benzoate + HCO3-.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete terephthalate decarboxylase activity (obsolete GO:0034947)","termid":"GO:0034947"}


id: MONDO:1012692
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A progressive hereditary neurodegenerative disorder that occurs in dogs and is characterized by neuronal degeneration and loss in the cerebellum, olivary nuclei, substantia nigra, and caudate nuclei due to a mutation in the SERAC1 gene.","definition_xrefs":["PMID:38003185","PMID:34490804"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease, non-human animal","termid":"MONDO:1011321"},{"relation_name":"is_a","term_name":"neurodegenerative disease, non-human animal","termid":"MONDO:1012953"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"canine multiple system degeneration, SERAC1-related, dog","secondary_identifiers":["OMIA:001468-9615"],"synonyms":[{"name":"CMSD","type":"exact"},{"name":"canine multiple system degeneration, dog","type":"related"}],"termid":"MONDO:1012692","xrefs":{"Monarch":{"xref_id":"1012692"}}}


id: SO:0000504
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"Genomic DNA of immunoglobulin/T-cell receptor gene in rearranged configuration including at least one D-gene, one DJ-gene and one C-gene.","direct_ancestors":[{"relation_name":"has_part","term_name":"D_gene_segment","termid":"SO:0000458"},{"relation_name":"has_part","term_name":"C_gene_segment","termid":"SO:0000478"},{"relation_name":"has_part","term_name":"DJ_gene_segment","termid":"SO:0000572"},{"relation_name":"is_a","term_name":"vertebrate_immunoglobulin_T_cell_receptor_rearranged_gene_cluster","termid":"SO:0000938"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"D_DJ_C_cluster","synonyms":[{"name":"D DJ C cluster","type":"exact"},{"name":"D-(DJ)-C-CLUSTER","type":"exact"}],"termid":"SO:0000504"}


id: GO:1904631
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucoside stimulus.","definition_xrefs":["GOC:TermGenie","PMID:16842873","GO_REF:0000071"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to glycoside","termid":"GO:1903416"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to glucoside","synonyms":[{"name":"response to glucosides","type":"exact"}],"termid":"GO:1904631"}


id: internal:cv_version
data:
  {"annotation_feature_type":"gene","cv_name":"cv_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cv_version","termid":"internal:cv_version"}


id: PBO:0052019
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"jumonji domain containing 8","termid":"PBO:0052019"}


id: PBO:0085651
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein involved in microtubule-related processes; GFP-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS; YLR412W is not an essential gene; similar to Arabidopsis SRR1 gene","termid":"PBO:0085651"}


id: PBO:0036050
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_histone_H3-K9_dimethylation_at_centromere_during_vegetative_growth","termid":"PBO:0036050"}


id: PBO:0049767
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HLA complex group 4 pseudogene 4","termid":"PBO:0049767"}


id: MONDO:0017905
data:
  {"annotated_genes":["SJAG_04743"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88981],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010389"}]},"cv_name":"mondo","definition":"A rare group of immunodeficiencies due to specific mutations in the inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG) or the cytochrome b-245, beta polypeptide (CYBB) genes. They are characterized by mycobacterial infections, occurring in males.","definition_xrefs":["Orphanet:319605"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inherited susceptibility to mycobacterial diseases","termid":"MONDO:0019146"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04743":null},"genotype_count":0,"is_obsolete":false,"name":"X-linked Mendelian susceptibility to mycobacterial diseases","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C4304413","SCTID:719814009","MEDGEN:930082"],"synonyms":[{"name":"X-linked MSMD","type":"exact"},{"name":"mendelian susceptibility to mycobacterial diseases, X-linked","type":"exact"}],"termid":"MONDO:0017905","terms_by_termid":{"MONDO:0010389":null},"xrefs":{"Monarch":{"xref_id":"0017905"}}}


id: PBO:0058526
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 6071","termid":"PBO:0058526"}


id: MONDO:0035824
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"KLHL7-related cold-induced sweating-like syndrome","secondary_identifiers":["Orphanet:603694","MEDGEN:1842368","UMLS:C5680211","GARD:22437"],"synonyms":[{"name":"KLHL7-related Crisponi-like syndrome","type":"exact"}],"termid":"MONDO:0035824","xrefs":{"Monarch":{"xref_id":"0035824"}}}


id: PBO:0088423
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial tRNA-specific 2-thiouridylase Slm3","termid":"PBO:0088423"}


id: MONDO:0014679
data:
  {"annotated_genes":["SJAG_04537"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86880],"is_not":false,"summary":null,"term":"MONDO:0014679"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"PI4KA-related disorder","termid":"MONDO:1040012"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04537":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0005559","MONDO:0002320"],"is_obsolete":false,"name":"polymicrogyria, perisylvian, with cerebellar hypoplasia and arthrogryposis","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:16130","MEDGEN:899982","OMIM:616531","UMLS:C4225295"],"synonyms":[{"name":"PMGYCHA","type":"related"},{"name":"polymicrogyria, perisylvian, with cerebellar hypoplasia and arthrogryposis","type":"exact"}],"termid":"MONDO:0014679","terms_by_termid":{"MONDO:0014679":null},"xrefs":{"Monarch":{"xref_id":"0014679"}}}


id: PBO:0081645
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 571","termid":"PBO:0081645"}


id: PBO:0066337
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"regulator of chromosome condensation 2","termid":"PBO:0066337"}


id: GO:0060196
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.","definition_xrefs":["GOC:tb","PMID:18075583","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of DNA-templated transcription","termid":"GO:0045893"},{"relation_name":"is_a","term_name":"regulation of antisense RNA transcription","termid":"GO:0060194"},{"relation_name":"positively_regulates","term_name":"antisense RNA transcription","termid":"GO:0009300"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0006351"},{"rel_name":"regulates","termid":"GO:0006351"},{"rel_name":"is_a","termid":"GO:0006355"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0006355","GO:0010467","GO:0006351","GO:0008150"],"is_obsolete":false,"name":"positive regulation of antisense RNA transcription","termid":"GO:0060196"}


id: PBO:0068563
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U2 small nuclear 14, pseudogene","termid":"PBO:0068563"}


id: PBO:0071666
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L37a pseudogene 7","termid":"PBO:0071666"}


id: GO:0120174
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A stress-inducible protein catabolic pathway that promotes protein quality control by accelerating the degradation of misfolded ER membrane and cytosolic proteins, as well as native proteins. The pathway starts with the activation, by stress, of the Nma111p/Ynm3p serine protease, which cleaves the stress-induced hydrophilin Roq1p, resulting in the generation of a Roq1p cleavage product that selectively interacts with Ubr1p, an E3 ubiquitin ligase. Interaction with the Ubr1p type-1 substrate binding site reprograms the substrate specificity of this ubiquitin ligase resulting in the selective proteasome-mediated degradation of misfolded and native proteins. The pathway ends with degradation of the protein by the cytoplasmic proteasome. Currently, NMA111, ROQ1, UBR1, RAD6, and CDC48 are considered to be involved in this quality control pathway.","definition_xrefs":["GOC:rl","GOC:rn","PMID:29861160"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to stress","termid":"GO:0033554"},{"relation_name":"is_a","term_name":"proteasome-mediated ubiquitin-dependent protein catabolic process","termid":"GO:0043161"},{"relation_name":"is_a","term_name":"response to nitrogen compound","termid":"GO:1901698"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0030163"},{"rel_name":"is_a","termid":"GO:0030163"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0030163","GO:0008150"],"is_obsolete":false,"name":"stress-induced homeostatically regulated protein degradation pathway","synonyms":[{"name":"SHRED pathway","type":"related"}],"termid":"GO:0120174"}


id: MONDO:0013775
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"coagulation protein disease","termid":"MONDO:0002242"},{"relation_name":"is_a","term_name":"hemorrhagic disease","termid":"MONDO:0002243"},{"relation_name":"is_a","term_name":"inherited thrombophilia","termid":"MONDO:0100240"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"thrombomodulin-related bleeding disorder","secondary_identifiers":["UMLS:C3280976","MEDGEN:482606","MESH:C566057","GARD:17726","DOID:0111908","OMIM:614486","Orphanet:436169"],"synonyms":[{"name":"THBD-related bleeding disorder","type":"exact"},{"name":"THBD-related coagulopathy","type":"exact"},{"name":"THPH12","type":"related"},{"name":"thrombomodulin-related coagulopathy","type":"exact"},{"name":"thrombophilia 12 due to thrombomodulin defect","type":"exact"},{"name":"thrombophilia due to thrombomodulin defect","type":"related"}],"termid":"MONDO:0013775","xrefs":{"Monarch":{"xref_id":"0013775"}}}


id: MONDO:0018624
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"headache disorder","termid":"MONDO:0021146"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spontaneous intracranial hypotension","secondary_identifiers":["GARD:21854","NORD:1901","Orphanet:443180","UMLS:C0751731","icd11.foundation:1304151002","MEDGEN:155914"],"synonyms":[{"name":"spontaneous cerebrospinal fluid leak","type":"exact"}],"termid":"MONDO:0018624","xrefs":{"Monarch":{"xref_id":"0018624"}}}


id: PBO:0059311
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial ribosomal protein L51 pseudogene 2","termid":"PBO:0059311"}


id: MONDO:0016831
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"melanocytic nevus","termid":"MONDO:0005073"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"linear verrucous nevus syndrome","secondary_identifiers":["GARD:3259","Orphanet:2611","MEDGEN:1806291","UMLS:C5679838"],"synonyms":[{"name":"linear hamartoma syndrome","type":"exact"}],"termid":"MONDO:0016831","xrefs":{"Monarch":{"xref_id":"0016831"}}}


id: MONDO:0018980
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Acrofacial dysostosis, Kennedy-Teebi type was reported as a new type of acrofacial dysostosis due to the presence of manifestations not usually seen in Nager syndrome (NS) such as microcephaly, blepharophimosis, microtia, a peculiar beakednose, cleft lip and palate, symmetrical involvement of the thumbs and great toes and developmental delay. It has since been suggested that these features can also be a part of the NS phenotype.","definition_xrefs":["Orphanet:64542"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acrofacial dysostosis","termid":"MONDO:0018237"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"acrofacial dysostosis, Kennedy-Teebi type","secondary_identifiers":["GARD:18859","SCTID:720427009","MEDGEN:929763","UMLS:C4304094"],"synonyms":[{"name":"Kennedy-Teebi syndrome","type":"exact"}],"termid":"MONDO:0018980","xrefs":{"Monarch":{"xref_id":"0018980"}}}


id: PR:O94275
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An E3 ubiquitin-protein ligase HECTD2 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO03811","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"E3 ubiquitin-protein ligase mug30 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBP8B7.27","secondary_identifiers":["UniProtKB:O94275"],"synonyms":[{"name":"Spom972h-HECTD2","type":"exact"},{"name":"meiotically up-regulated gene 30 protein (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O94275"}


id: FYPO:0004475
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the initiation of nuclear DNA replication is decreased. Initiation may be affected at one or more origins.","definition_xrefs":["PomBase:mah","PMID:22970243"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal mitotic DNA replication initiation","termid":"FYPO:0001344"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000293"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000631","FYPO:0000293","FYPO:0000002","FYPO:0001320","FYPO:0005447"],"is_obsolete":false,"name":"decreased mitotic DNA replication initiation","synonyms":[{"name":"decreased DNA replication initiation during mitotic cell cycle","type":"exact"},{"name":"decreased DNA replication initiation during vegetative growth","type":"exact"},{"name":"reduced mitotic DNA replication initiation","type":"exact"}],"termid":"FYPO:0004475"}


id: PBO:0065429
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proteasome 26S subunit, ATPase 1 pseudogene 2","termid":"PBO:0065429"}


id: PATO:0002148
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A virulence that is relatively high.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"increased_in_magnitude_relative_to","term_name":"normal","termid":"PATO:0000461"},{"relation_name":"is_a","term_name":"virulence","termid":"PATO:0002146"},{"relation_name":"is_a","term_name":"increased object quality","termid":"PATO:0002305"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"increased virulence","termid":"PATO:0002148"}


id: PBO:0109054
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TRIB1 associated lncRNA","termid":"PBO:0109054"}


id: GO:0060722
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell population proliferation","termid":"GO:0008283"},{"relation_name":"part_of","term_name":"embryonic placenta development","termid":"GO:0001892"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cell proliferation involved in embryonic placenta development","termid":"GO:0060722"}


id: GO:0043425
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a basic Helix-Loop-Helix (bHLH) superfamily of transcription factors, important regulatory components in transcriptional networks of many developmental pathways.","definition_xrefs":["PMID:9144210"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA-binding transcription factor binding","termid":"GO:0140297"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005488","GO:0005515"],"is_obsolete":false,"name":"bHLH transcription factor binding","termid":"GO:0043425"}


id: PBO:0068253
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 28S ribosomal N5","termid":"PBO:0068253"}


id: PBO:0088336
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ER zinc exporter, ZIP family Zip3","termid":"PBO:0088336"}


id: PBO:0044134
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"C-terminal binding protein 2","termid":"PBO:0044134"}


id: GO:0034716
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that contains Gemin3 (DDX20), Gemin4, and Gemin5, and can bind to snRNAs; may be an intermediate in SMN complex assembly.","definition_xrefs":["PMID:17640873","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracellular protein-containing complex","termid":"GO:0140535"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"Gemin3-Gemin4-Gemin5 complex","termid":"GO:0034716"}


id: MONDO:0016990
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An instance of prothrombin deficiency that is acquired during the lifetime of the individual.","definition_xrefs":["MONDO:patterns/acquired"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"congenital prothrombin deficiency","termid":"MONDO:0013361"},{"relation_name":"is_a","term_name":"prothrombin deficiency","termid":"MONDO:0024307"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"acquired prothrombin deficiency","secondary_identifiers":["MESH:C538174","Orphanet:26348","NCIT:C131622","MEDGEN:140275","SCTID:4152002","UMLS:C0392610","GARD:475"],"synonyms":[{"name":"acquired factor II deficiency","type":"related"},{"name":"acquired hypoprothrombinemia","type":"exact"},{"name":"acquired prothrombin deficiency","type":"exact"},{"name":"hypoprothrombinemia, acquired","type":"related"}],"termid":"MONDO:0016990","xrefs":{"Monarch":{"xref_id":"0016990"}}}


id: FYPO:0002890
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype in which the size, shape, or structure of the horsetail nucleus is abnormal. The horsetail nucleus forms during the rapid oscillatory movement at meiotic prophase I.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal nuclear morphology during meiosis I","termid":"FYPO:0005651"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002403"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0002403","FYPO:0000002"],"is_obsolete":false,"name":"abnormal horsetail nucleus morphology","synonyms":[{"name":"abnormal horsetail nuclear morphology","type":"exact"}],"termid":"FYPO:0002890"}


id: MONDO:0024343
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"exanthem","termid":"MONDO:0006547"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"pityriasis simplex","secondary_identifiers":["MEDGEN:602609","ICD9:690.18","UMLS:C0423775","SCTID:200767005"],"synonyms":[{"name":"dandruff","type":"related"},{"name":"furfuracea","type":"related"},{"name":"pityriasis simplex","type":"exact"}],"termid":"MONDO:0024343","xrefs":{"Monarch":{"xref_id":"0024343"}}}


id: GO:1900437
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus.","definition_xrefs":["GOC:TermGenie","GOC:di"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of response to stimulus","termid":"GO:0048583"},{"relation_name":"is_a","term_name":"regulation of filamentous growth of a population of unicellular organisms","termid":"GO:1900428"},{"relation_name":"regulates","term_name":"filamentous growth of a population of unicellular organisms in response to chemical stimulus","termid":"GO:0036171"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus","termid":"GO:1900437"}


id: MONDO:0009763
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hypoventilation syndrome in very obese persons with excessive adipose tissue around the abdomen and diaphragm is characterized by diminished to absent ventilatory chemoresponsiveness; chronic hypoxia; hypercapnia; polycythemia; and long periods of sleep during day and night (hypersomnolence). It is a condition often related to obstructive sleep apnea but can occur separately.","definition_xrefs":["MESH:D010845"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"obesity-hypoventilation syndrome","secondary_identifiers":["UMLS:C0031880","EFO:1001382","OMIM:257500","NANDO:1200752","MEDGEN:18472","ICD9:786.09","SCTID:190966007"],"synonyms":[{"name":"Pickwickian syndrome","type":"related"},{"name":"obesity-hypoventilation syndrome","type":"exact"}],"termid":"MONDO:0009763","xrefs":{"Monarch":{"xref_id":"0009763"}}}


id: PBO:0085955
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein of unknown function; null mutant lacks mitochondrial DNA and cannot grow on glycerol; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies","termid":"PBO:0085955"}


id: MONDO:0800419
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary neoplastic syndrome","termid":"MONDO:0015356"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"breast cancer, familial, susceptibility to, 2","termid":"MONDO:0800419","xrefs":{"Monarch":{"xref_id":"0800419"}}}


id: PBO:0002356
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ace2 Dependent Gene","termid":"PBO:0002356"}


id: GO:1990522
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the nematode tail spike is generated and organized. An example of this process is seen in C. elegans, where the tapered tail spike is formed during embryogenesis by a filamentous process that passes posteriorly through hyp10, the tail ventral hypodermis; the filamentous process is formed by a binucleate cell, the tail-spike cell, that subsequently undergoes programmed cell death.","definition_xrefs":["GOC:kmv","PMID:17329362","PMID:6684600"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure morphogenesis","termid":"GO:0009653"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"tail spike morphogenesis","secondary_identifiers":["WBbt:0006979","WBbt:0008072"],"termid":"GO:1990522"}


id: GO:0071308
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menaquinone (vitamin K2) stimulus.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to menaquinone","termid":"GO:0032572"},{"relation_name":"is_a","term_name":"cellular response to vitamin K","termid":"GO:0071307"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to menaquinone","synonyms":[{"name":"cellular response to menatetrenone","type":"exact"},{"name":"cellular response to vitamin K2","type":"exact"}],"termid":"GO:0071308"}


id: MONDO:0015295
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Intractable diarrhea-choanal atresia-eye anomalies syndrome is characterized by the association of intractable diarrhea of infancy with choanal atresia. Short stature, a prominent and broad nasal bridge, micrognathia, single palmar creases, chronic corneal inflammation, cytopenia, and abnormal hair texture were also reported. So far, the syndrome has been described in three children from the same family. The absence of intellectual deficit and immune deficiency allow this syndrome to be distinguished from other forms of intractable diarrhea of infancy described previously.","definition_xrefs":["Orphanet:137622"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intestinal disorder","termid":"MONDO:0005020"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"intractable diarrhea-choanal atresia-eye anomalies syndrome","secondary_identifiers":["MEDGEN:929976","UMLS:C4304307","GARD:19882"],"termid":"MONDO:0015295","xrefs":{"Monarch":{"xref_id":"0015295"}}}


id: PBO:0024863
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pumilio family RNA-binding protein Puf1 (predicted)","termid":"PBO:0024863"}


id: MONDO:1010597
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hyperthyroidism that occurs in rabbit.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hyperthyroidism, non-human animal","termid":"MONDO:1010055"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hyperthyroidism, rabbit","secondary_identifiers":["OMIA:000511-9986"],"termid":"MONDO:1010597","xrefs":{"Monarch":{"xref_id":"1010597"}}}


id: PBO:0060939
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NFE2 like bZIP transcription factor 2","termid":"PBO:0060939"}


id: GO:0006282
data:
  {"annotated_genes":["SJAG_02104","SJAG_03160","SJAG_03048","SJAG_03417","SJAG_01205","SJAG_00823","SJAG_00369","SJAG_02058","SJAG_04457","SJAG_03695","SJAG_00573"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[104185],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:2001033"},{"annotations":[113612],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1904332"},{"annotations":[113890,119141],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0045739"},{"annotations":[95696,112029],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:2000781"},{"annotations":[112776],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905168"},{"annotations":[109242],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:2001034"},{"annotations":[74367,92722],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:2000779"},{"annotations":[111162],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010569"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of DNA repair.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of DNA metabolic process","termid":"GO:0051052"},{"relation_name":"is_a","term_name":"regulation of cellular response to stress","termid":"GO:0080135"},{"relation_name":"regulates","term_name":"DNA repair","termid":"GO:0006281"}],"gene_count":11,"genes_by_uniquename":{"SJAG_00369":null,"SJAG_00573":null,"SJAG_00823":null,"SJAG_01205":null,"SJAG_02058":null,"SJAG_02104":null,"SJAG_03048":null,"SJAG_03160":null,"SJAG_03417":null,"SJAG_03695":null,"SJAG_04457":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006259"},{"rel_name":"regulates","termid":"GO:0006281"}],"interesting_parent_ids":["GO:0006259","GO:0008150","GO:0006281"],"is_obsolete":false,"name":"regulation of DNA repair","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0006282","terms_by_termid":{"GO:0010569":null,"GO:0045739":null,"GO:1904332":null,"GO:1905168":null,"GO:2000779":null,"GO:2000781":null,"GO:2001033":null,"GO:2001034":null}}


id: GO:0033463
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"A triplet codon-amino acid adaptor activity that recognizes a GGA codon.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"triplet codon-amino acid adaptor activity","termid":"GO:0030533"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003723"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0060090"}],"interesting_parent_ids":["GO:0060090","GO:0003723","GO:0005488","GO:0003674"],"is_obsolete":false,"name":"GGA codon-amino acid adaptor activity","synonyms":[{"name":"glycine tRNA","type":"related"}],"termid":"GO:0033463"}


id: GO:0140158
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A family of collagens containing multiple von Willebrand factor A (vWA) domains.","definition_xrefs":["PMID:21421911"],"direct_ancestors":[{"relation_name":"is_a","term_name":"collagen trimer","termid":"GO:0005581"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"von-Willerbrand-factor-A-domain-rich collagen trimer","termid":"GO:0140158"}


id: PBO:0082785
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of the TOM (translocase of outer membrane) complex; responsible for recognition and initial import steps for all mitochondrially directed proteins; acts as a receptor for incoming precursor proteins","termid":"PBO:0082785"}


id: GO:0080105
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 6-methylthiopropyl-glucosinolate = 6-methylsulfinylpropyl-glucosinolate.","definition_xrefs":["PMID:18799661"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen","termid":"GO:0016705"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"6-methylthiopropyl glucosinolate S-oxygenase activity","termid":"GO:0080105"}


id: PBO:0078845
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transient receptor potential cation channel subfamily C member 1","termid":"PBO:0078845"}


id: PBO:0053493
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 471","termid":"PBO:0053493"}


id: PBO:0057564
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 759","termid":"PBO:0057564"}


id: PBO:0090988
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"rRNA processing protein Rrp36","termid":"PBO:0090988"}


id: GO:1903428
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of reactive oxygen species biosynthetic process.","definition_xrefs":["GOC:bf","GO_REF:0000058","GOC:PARL","PMID:24252804","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of biosynthetic process","termid":"GO:0009891"},{"relation_name":"is_a","term_name":"regulation of reactive oxygen species biosynthetic process","termid":"GO:1903426"},{"relation_name":"is_a","term_name":"positive regulation of reactive oxygen species metabolic process","termid":"GO:2000379"},{"relation_name":"positively_regulates","term_name":"reactive oxygen species biosynthetic process","termid":"GO:1903409"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of reactive oxygen species biosynthetic process","synonyms":[{"name":"activation of ROS formation","type":"related"},{"name":"activation of ROS generation","type":"related"},{"name":"activation of reactive oxygen species anabolism","type":"narrow"},{"name":"activation of reactive oxygen species biosynthesis","type":"narrow"},{"name":"activation of reactive oxygen species biosynthetic process","type":"narrow"},{"name":"activation of reactive oxygen species formation","type":"narrow"},{"name":"activation of reactive oxygen species generation","type":"related"},{"name":"activation of reactive oxygen species synthesis","type":"narrow"},{"name":"positive regulation of ROS formation","type":"related"},{"name":"positive regulation of ROS generation","type":"related"},{"name":"positive regulation of reactive oxygen species anabolism","type":"exact"},{"name":"positive regulation of reactive oxygen species biosynthesis","type":"exact"},{"name":"positive regulation of reactive oxygen species formation","type":"exact"},{"name":"positive regulation of reactive oxygen species generation","type":"related"},{"name":"positive regulation of reactive oxygen species synthesis","type":"exact"},{"name":"up regulation of ROS formation","type":"related"},{"name":"up regulation of ROS generation","type":"related"},{"name":"up regulation of reactive oxygen species anabolism","type":"exact"},{"name":"up regulation of reactive oxygen species biosynthesis","type":"exact"},{"name":"up regulation of reactive oxygen species biosynthetic process","type":"exact"},{"name":"up regulation of reactive oxygen species formation","type":"exact"},{"name":"up regulation of reactive oxygen species generation","type":"related"},{"name":"up regulation of reactive oxygen species synthesis","type":"exact"},{"name":"up-regulation of ROS formation","type":"related"},{"name":"up-regulation of ROS generation","type":"related"},{"name":"up-regulation of reactive oxygen species anabolism","type":"exact"},{"name":"up-regulation of reactive oxygen species biosynthesis","type":"exact"},{"name":"up-regulation of reactive oxygen species biosynthetic process","type":"exact"},{"name":"up-regulation of reactive oxygen species formation","type":"exact"},{"name":"up-regulation of reactive oxygen species generation","type":"related"},{"name":"up-regulation of reactive oxygen species synthesis","type":"exact"},{"name":"upregulation of ROS formation","type":"related"},{"name":"upregulation of ROS generation","type":"related"},{"name":"upregulation of reactive oxygen species anabolism","type":"exact"},{"name":"upregulation of reactive oxygen species biosynthesis","type":"exact"},{"name":"upregulation of reactive oxygen species biosynthetic process","type":"exact"},{"name":"upregulation of reactive oxygen species formation","type":"exact"},{"name":"upregulation of reactive oxygen species generation","type":"related"},{"name":"upregulation of reactive oxygen species synthesis","type":"exact"}],"termid":"GO:1903428"}


id: GO:0075502
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Induction of endosome membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with the capsid. Occurs after internalization of the virus through the endosomal pathway, and results in delivery of the virus contents into the host cell cytoplasm.","definition_xrefs":["GOC:jl","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"permeabilization of host organelle membrane involved in viral entry into host cell","termid":"GO:0039665"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"endosome membrane permeabilization involved in viral entry into host cell","secondary_identifiers":["GO:0075518"],"synonyms":[{"name":"viral entry into host cell via caveolae-mediated endocytosis followed by endosome membrane","type":"related"},{"name":"viral entry into host cell via clathrin-mediated endocytosis followed by endosome membrane permeabilization","type":"related"}],"termid":"GO:0075502"}


id: MONDO:0042956
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Saal-Bulas syndrome","secondary_identifiers":["MEDGEN:419079","UMLS:C2931439","MESH:C537193"],"synonyms":[{"name":"Saal Bulas syndrome","type":"related"},{"name":"ectrodactyly, diaphragmatic hernia, congenital heart defect, and agenesis of the corpus callosum","type":"related"}],"termid":"MONDO:0042956","xrefs":{"Monarch":{"xref_id":"0042956"}}}


id: PBO:0089966
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"autophagy associated phospholipid scramblase Atg9","termid":"PBO:0089966"}


id: GO:1905044
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration.","definition_xrefs":["GOC:BHF","GO_REF:0000058","GOC:TermGenie","GOC:rph","GOC:BHF_miRNA","PMID:22393241"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of Schwann cell proliferation","termid":"GO:0010624"},{"relation_name":"regulates","term_name":"Schwann cell proliferation involved in axon regeneration","termid":"GO:0014011"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of Schwann cell proliferation involved in axon regeneration","termid":"GO:1905044"}


id: PBO:0073418
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"senataxin","termid":"PBO:0073418"}


id: GO:0009473
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete cytochrome c7 (triheme) (obsolete GO:0009473)","synonyms":[{"name":"cytochrome c7 (triheme)","type":"exact"}],"termid":"GO:0009473"}


id: PBO:0042542
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cyclin dependent kinase 8 pseudogene 1","termid":"PBO:0042542"}


id: GO:0140466
data:
  {"annotated_genes":["SJAG_02457"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[91089],"is_not":false,"summary":null,"term":"GO:0140466"}]},"cv_name":"biological_process","definition":"The directed movement of iron sulfur clusters from inside the mitochondrion into the cytosol by crossing the inner mitochondrial membrane.","definition_xrefs":["PMID:31040179"],"direct_ancestors":[{"relation_name":"is_a","term_name":"iron-sulfur cluster transmembrane transport","termid":"GO:1902497"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02457":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0051179","GO:0008150","GO:0055085"],"is_obsolete":false,"name":"iron-sulfur cluster export from the mitochondrion","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0140466","terms_by_termid":{"GO:0140466":null}}


id: PBO:0086909
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative vacuolar membrane transporter for cationic amino acids; likely contributes to amino acid homeostasis by exporting cationic amino acids from the vacuole; positive regulation by Lys14p suggests that lysine may be the primary substrate; member of the PQ-loop family, with seven transmembrane domains; similar to mammalian PQLC2 vacuolar transporter; RTC2 has a paralog, YPQ1, that arose from the whole genome duplication","termid":"PBO:0086909"}


id: PR:O74557
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- cbr1 gene.","definition_xrefs":["UniProtKB:O74557","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADH-cytochrome b5 reductase 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC970.03","synonyms":[{"name":"Spom972h-cbr1","type":"exact"},{"name":"microsomal cytochrome b reductase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O74557"}


id: MONDO:0000902
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Corpus callosum agenesis-neuropathy is a neurodegenerative disorder characterized by severe progressive sensorimotor neuropathy beginning in infancy with resulting hypotonia, areflexia, amyotrophy and variable degrees of dysgenesis of the corpus callosum. Additional features include mild-to-severe intellectual and developmental delays, and psychiatric manifestations that include paranoid delusions, depression, hallucinations, and \\\"autistic-like\\\" features. Affected individuals are usually wheelchair restricted in the second decade of life and die in the third decade of life. The disease is inherited as an autosomal recessive trait.","definition_xrefs":["Orphanet:1496"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inherited neurodegenerative disorder","termid":"MONDO:0024237"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"agenesis of the corpus callosum with peripheral neuropathy","secondary_identifiers":["UMLS:C0795950","OMIM:218000","DOID:0060600","DOID:0090003","MEDGEN:162893","MESH:C536446","SCTID:702439002","GARD:1537"],"synonyms":[{"name":"ACCPN","type":"related"},{"name":"Andermann syndrome","type":"exact"},{"name":"Charlevoix disease","type":"exact"},{"name":"HMSN/ACC","type":"related"},{"name":"agenesis of corpus callosum with neuronopathy","type":"related"},{"name":"agenesis of corpus callosum with peripheral neuropathy","type":"related"},{"name":"agenesis of corpus callosum with polyneuropathy","type":"related"},{"name":"agenesis of the corpus callosum with peripheral neuropathy","type":"exact"},{"name":"corpus callosum agenesis neuronopathy","type":"related"},{"name":"corpus callosum agenesis-neuronopathy syndrome","type":"exact"},{"name":"corpus callosum, agenesis of, with neuronopathy","type":"related"},{"name":"hereditary motor and sensory neuropathy with agenesis of the corpus callosum","type":"exact"},{"name":"peripheral neuropathy associated with agenesis of the corpus callosum","type":"exact"},{"name":"polyneuropathy, sensorimotor, with or without agenesis of the corpus callosum","type":"related"}],"termid":"MONDO:0000902","xrefs":{"Monarch":{"xref_id":"0000902"}}}


id: RO:0002517
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"inverse of has start sequence","direct_ancestors":[{"relation_name":"is_a","term_name":"is_subsequence_of","termid":"RO:0002525"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"is_start_sequence_of","termid":"RO:0002517"}


id: PATO:0002391
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A shape quality inhering in a bearer by virtue of the bearer's having three rays or radiating branches.","definition_xrefs":["merriam-webster:merriam-webster"],"direct_ancestors":[{"relation_name":"is_a","term_name":"shape","termid":"PATO:0000052"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"triradiate","termid":"PATO:0002391"}


id: PBO:0058284
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4660","termid":"PBO:0058284"}


id: MONDO:1010025
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Wolff-Parkinson-White syndrome that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cardiomyopathy, non-human animal","termid":"MONDO:1010010"},{"relation_name":"is_a","term_name":"hereditary disease, non-human animal","termid":"MONDO:1011321"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Wolff-Parkinson-White syndrome, non-human animal","secondary_identifiers":["OMIA:001194"],"termid":"MONDO:1010025","xrefs":{"Monarch":{"xref_id":"1010025"}}}


id: GO:0016024
data:
  {"annotated_genes":["SJAG_01233","SJAG_03563","SJAG_00426","SJAG_00168"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[81804,114874,116534,121035],"is_not":false,"summary":null,"term":"GO:0016024"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate.","definition_xrefs":["PMID:24533860"],"direct_ancestors":[{"relation_name":"is_a","term_name":"CDP-diacylglycerol metabolic process","termid":"GO:0046341"},{"relation_name":"is_a","term_name":"glycerophospholipid biosynthetic process","termid":"GO:0046474"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00168":null,"SJAG_00426":null,"SJAG_01233":null,"SJAG_03563":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006629","GO:0008150"],"is_obsolete":false,"name":"CDP-diacylglycerol biosynthetic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null,"PMID:25318672":null},"synonyms":[{"name":"CDP-diacylglycerol anabolism","type":"exact"},{"name":"CDP-diacylglycerol biosynthesis","type":"exact"},{"name":"CDP-diacylglycerol formation","type":"exact"},{"name":"CDP-diacylglycerol synthesis","type":"exact"}],"termid":"GO:0016024","terms_by_termid":{"GO:0016024":null}}


id: PBO:0000393
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2.7.1.1","termid":"PBO:0000393"}


id: MONDO:0009282
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A disorder of fatty acid and amino acid oxidation, caused by mutations in ETFDH, ETFA, or ETFB, and is a clinically heterogeneous disorder ranging from a severe neonatal presentation with metabolic acidosis, cardiomyopathy and liver disease, to a mild childhood/adult disease with episodic metabolic decompensation, muscle weakness, and respiratory failure.","definition_xrefs":["Orphanet:26791"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glutaric aciduria","termid":"MONDO:0000129"},{"relation_name":"is_a","term_name":"inborn mitochondrial metabolism disorder","termid":"MONDO:0004069"},{"relation_name":"is_a","term_name":"acyl-CoA dehydrogenase deficiency","termid":"MONDO:0017714"},{"relation_name":"is_a","term_name":"familial hypertrophic cardiomyopathy","termid":"MONDO:0024573"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002525"},{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0005267"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0002525","MONDO:0005267","MONDO:0005066","MONDO:0004069"],"is_obsolete":false,"name":"multiple acyl-CoA dehydrogenase deficiency","secondary_identifiers":["ICD10CM:E71.313","GARD:6523","DOID:0060358","NORD:1192","MEDGEN:75696","icd11.foundation:977130875","NANDO:2200502","NCIT:C84907","NANDO:1200801","OMIM:231680","UMLS:C0268596"],"synonyms":[{"name":"EMA","type":"related"},{"name":"Etfa deficiency","type":"narrow"},{"name":"Etfb deficiency","type":"narrow"},{"name":"Etfdh deficiency","type":"narrow"},{"name":"Ga 2","type":"related"},{"name":"Glutaric Aciduria Type II","type":"exact"},{"name":"MAD deficiency","type":"exact"},{"name":"MADD","type":"exact"},{"name":"electron transfer flavoprotein deficiency","type":"exact"},{"name":"electron transfer flavoprotein ubiquinone oxidoreductase deficiency","type":"exact"},{"name":"ethylmalonic-Adipicaciduria","type":"related"},{"name":"glutaric acidemia 2","type":"related"},{"name":"glutaric acidemia 2A","type":"narrow"},{"name":"glutaric acidemia 2B","type":"narrow"},{"name":"glutaric acidemia 2C","type":"narrow"},{"name":"glutaric acidemia IIA","type":"narrow"},{"name":"glutaric acidemia IIB","type":"narrow"},{"name":"glutaric acidemia IIC","type":"narrow"},{"name":"glutaric acidemia type 2","type":"exact"},{"name":"glutaric acidemia type II","type":"exact"},{"name":"glutaric aciduria 2","type":"related"},{"name":"glutaric aciduria type 2","type":"exact"},{"name":"glutaric aciduria, type 2","type":"exact"},{"name":"multiple acyl Coenzyme A dehydrogenase deficiency","type":"exact"},{"name":"multiple acyl-CoA dehydrogenase deficiency","type":"exact"}],"termid":"MONDO:0009282","xrefs":{"Monarch":{"xref_id":"0009282"}}}


id: PBO:0081521
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 430","termid":"PBO:0081521"}


id: FYPO:0002192
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"OBSOLETE. A cell population phenotype in which a cell undergoes one or a few rounds of cell division before cells die, resulting in the formation a colony that contains only a few inviable cells that have a normal volume and spheroid shape, and contain one or more septa each. Up to 6 rounds of cell division (generating 64 cells) may be observed, but 3 divisions or fewer is more typical.","definition_xrefs":["PomBase:mah","PomBase:vw"],"gene_count":0,"genotype_count":0,"name":"obsolete inviable microcolony, normal volume septated spheroid cells (obsolete FYPO:0002192)","synonyms":[{"name":"inviable microcolony, normal volume septated rounded cells","type":"exact"},{"name":"inviable microcolony, normal volume septated spheroid vegetative cells","type":"exact"}],"termid":"FYPO:0002192"}


id: MONDO:0017300
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Congenital pericardium anomaly comprises a group of rare congenital cardiac malformations characterized by the complete (Congenital complete agenesis of pericardium) or partial absence of the pericardium (Congenital partial agenesis of pericardium), or by the presence of pericardial cysts (Pleuropericardial cyst).","definition_xrefs":["Orphanet:2846"],"direct_ancestors":[{"relation_name":"is_a","term_name":"congenital heart malformation","termid":"MONDO:0019512"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"congenital pericardium anomaly","secondary_identifiers":["SCTID:93018000","icd11.foundation:1188459532","UMLS:C0685699","GARD:18779","ICD9:746.89","MEDGEN:672640"],"termid":"MONDO:0017300","xrefs":{"Monarch":{"xref_id":"0017300"}}}


id: PBO:0040646
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bromodomain adjacent to zinc finger domain 1B","termid":"PBO:0040646"}


id: PBO:0080172
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"voltage dependent anion channel 1 pseudogene 7","termid":"PBO:0080172"}


id: GO:0002562
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which immune receptor genes are diversified through recombination of the germline genetic elements within a single genetic locus.","definition_xrefs":["PMID:16166509","GOC:add","PMID:16102575","ISBN:0781735149"],"direct_ancestors":[{"relation_name":"is_a","term_name":"somatic diversification of immune receptors","termid":"GO:0002200"},{"relation_name":"is_a","term_name":"somatic cell DNA recombination","termid":"GO:0016444"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006310"},{"rel_name":"is_a","termid":"GO:0006259"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0006310","GO:0006259"],"is_obsolete":false,"name":"somatic diversification of immune receptors via germline recombination within a single locus","termid":"GO:0002562"}


id: MONDO:0028795
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete rare genetic systemic or rheumatologic disease (obsolete MONDO:0028795)","secondary_identifiers":["Orphanet:271870"],"termid":"MONDO:0028795","xrefs":{"Monarch":{"xref_id":"0028795"}}}


id: GO:0004166
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UDP + dolichyl N-acetyl-alpha-D-glucosaminyl phosphate.","definition_xrefs":["EC:2.4.1.153"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acetylglucosaminyltransferase activity","termid":"GO:0008375"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016757"}],"interesting_parent_ids":["GO:0003824","GO:0016740","GO:0016757","GO:0003674"],"is_obsolete":false,"name":"dolichyl-phosphate alpha-N-acetylglucosaminyltransferase activity","secondary_identifiers":["MetaCyc:2.4.1.153-RXN","RHEA:14693","GO:0004101"],"synonyms":[{"name":"UDP-N-acetyl-D-glucosamine:dolichyl-phosphate alpha-N-acetyl-D-glucosaminyltransferase activity","type":"related"},{"name":"UDP-N-acetylglucosamine-dolichol phosphate N-acetylglucosaminyltransferase activity","type":"related"},{"name":"dolichyl phosphate N-acetylglucosaminyltransferase activity","type":"related"},{"name":"dolichyl phosphate acetylglucosaminyltransferase activity","type":"related"},{"name":"dolichyl-phosphate N-acetylglucosaminyltransferase activity","type":"related"},{"name":"dolichyl-phosphate acetylglucosaminyltransferase activity","type":"related"},{"name":"uridine diphosphoacetylglucosamine-dolichol phosphate acetylglucosaminyltransferase activity","type":"related"}],"termid":"GO:0004166"}


id: PR:O74956
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mrps8 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O74956"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"37S ribosomal protein subunit S8, mitochondrial (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC736.10c","synonyms":[{"name":"Spom972h-mrps8","type":"exact"}],"termid":"PR:O74956"}


id: GO:0000972
data:
  {"annotated_genes":["SJAG_01374","SJAG_03299","SJAG_04379","SJAG_02757","SJAG_04148","SJAG_00298","SJAG_04347","SJAG_03986"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[75489,76876,78449,82160],"is_not":false,"summary":null,"term":"GO:0000972"},{"annotations":[71629,77320,72137,76105],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000973"}]},"cv_name":"biological_process","definition":"The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery. In S. cerevisiae, this process involves cis-acting DNA sequences such as the TATA box and upstream activating sequence (UAS) elements, trans-acting transcriptional activators, and also the 3'-UTR of the transcript.","definition_xrefs":["GOC:krc","PMID:18614049"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chromosome organization","termid":"GO:0051276"}],"gene_count":8,"genes_by_uniquename":{"SJAG_00298":null,"SJAG_01374":null,"SJAG_02757":null,"SJAG_03299":null,"SJAG_03986":null,"SJAG_04148":null,"SJAG_04347":null,"SJAG_04379":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery","references_by_uniquename":{"GO_REF:0000033":null},"termid":"GO:0000972","terms_by_termid":{"GO:0000972":null,"GO:0000973":null}}


id: FYPO:0000872
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 occurs to a lower extent than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal histone H3-K9 methylation during vegetative growth","termid":"FYPO:0000458"},{"relation_name":"is_a","term_name":"decreased histone methylation during vegetative growth","termid":"FYPO:0000870"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002274"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000002","FYPO:0001985","FYPO:0002494","FYPO:0001320","FYPO:0002274"],"is_obsolete":false,"name":"decreased histone H3-K9 methylation during vegetative growth","synonyms":[{"name":"decreased histone H3 K9 methylation during vegetative growth","type":"exact"},{"name":"decreased histone H3-K9 methylation during mitotic cell cycle","type":"related"},{"name":"decreased histone H3K9me during vegetative growth","type":"exact"},{"name":"decreased histone lysine H3 K9 methylation during vegetative growth","type":"exact"},{"name":"reduced histone H3-K9 methylation during vegetative growth","type":"exact"}],"termid":"FYPO:0000872"}


id: PBO:0051777
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"IQ motif containing with AAA domain 1 like","termid":"PBO:0051777"}


id: GO:0019212
data:
  {"annotated_genes":["SJAG_03272","SJAG_04627","SJAG_04999","SJAG_03309","SJAG_02380"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[72037,91195],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004864"},{"annotations":[89669,76348,77793],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004865"}]},"cv_name":"molecular_function","definition":"Binds to and stops, prevents or reduces the activity of a phosphatase.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"enzyme inhibitor activity","termid":"GO:0004857"},{"relation_name":"is_a","term_name":"phosphatase regulator activity","termid":"GO:0019208"}],"gene_count":5,"genes_by_uniquename":{"SJAG_02380":null,"SJAG_03272":null,"SJAG_03309":null,"SJAG_04627":null,"SJAG_04999":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0004857"},{"rel_name":"is_a","termid":"GO:0098772"},{"rel_name":"is_a","termid":"GO:0140678"},{"rel_name":"is_a","termid":"GO:0030234"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0098772","GO:0030234","GO:0004857","GO:0140678"],"is_obsolete":false,"name":"phosphatase inhibitor activity","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0019212","terms_by_termid":{"GO:0004864":null,"GO:0004865":null}}


id: SO:0000006
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A region amplified by a PCR reaction.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"reagent","termid":"SO:0000695"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PCR_product","secondary_identifiers":["http://en.wikipedia.org/wiki/RAPD"],"synonyms":[{"name":"PCR product","type":"exact"},{"name":"amplicon","type":"related"}],"termid":"SO:0000006"}


id: PBO:0059273
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial ribosomal protein L35 pseudogene 2","termid":"PBO:0059273"}


id: MONDO:0005747
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An disease caused by infection with Enterovirus.","definition_xrefs":["MONDO:patterns/specific_infectious_disease_by_agent"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Picornaviridae infectious disease","termid":"MONDO:0005914"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"enterovirus infectious disease","secondary_identifiers":["MEDGEN:8647","EFO:0007255","ICD9:079.89","MESH:D004769","UMLS:C0014378","SCTID:53648006"],"synonyms":[{"name":"Enterovirus caused disease or disorder","type":"exact"},{"name":"Enterovirus disease or disorder","type":"exact"},{"name":"Enterovirus infection","type":"related"},{"name":"Enterovirus infectious disease","type":"exact"},{"name":"disease caused by enterovirus","type":"related"},{"name":"disease due to enterovirus","type":"exact"},{"name":"enteroviral infection","type":"related"},{"name":"enterovirus infection","type":"related"},{"name":"enterovirus infectious disease","type":"exact"},{"name":"infection, Enterovirus","type":"related"},{"name":"infections, Enterovirus","type":"related"}],"termid":"MONDO:0005747","xrefs":{"Monarch":{"xref_id":"0005747"}}}


id: GO:0070485
data:
  {"annotated_genes":["SJAG_00265"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[103287],"is_not":false,"summary":null,"term":"GO:0070485"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one.","definition_xrefs":["GOC:mah","GOC:cjk"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dehydro-D-arabinono-1,4-lactone metabolic process","termid":"GO:0070484"},{"relation_name":"is_a","term_name":"lactone biosynthetic process","termid":"GO:1901336"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00265":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"dehydro-D-arabinono-1,4-lactone biosynthetic process","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"dehydro-D-arabinono-1,4-lactone anabolism","type":"exact"},{"name":"dehydro-D-arabinono-1,4-lactone biosynthesis","type":"exact"},{"name":"dehydro-D-arabinono-1,4-lactone formation","type":"exact"},{"name":"dehydro-D-arabinono-1,4-lactone synthesis","type":"exact"}],"termid":"GO:0070485","terms_by_termid":{"GO:0070485":null}}


id: GO:0000955
data:
  {"annotated_genes":["SJAG_03743","SJAG_04842","SJAG_02734"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[72913,75619,73236],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000949"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols or carboxylic acids containing one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives, sometimes referred to as fusel acids, may be produced instead of alcohols.","definition_xrefs":["PMID:18281432","GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amino acid catabolic process","termid":"GO:0009063"}],"gene_count":3,"genes_by_uniquename":{"SJAG_02734":null,"SJAG_03743":null,"SJAG_04842":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006520"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006520","GO:0008150"],"is_obsolete":false,"name":"amino acid catabolic process via Ehrlich pathway","references_by_uniquename":{"GO_REF:0000033":null},"termid":"GO:0000955","terms_by_termid":{"GO:0000949":null}}


id: MONDO:0011468
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hereditary motor and sensory neuropathy, Okinawa type is a rare, genetic, axonal hereditary motor and sensory neuropathy characterized by the adult-onset of slowly progressive, symmetric, proximal dominant muscle weakness and atrophy, painful muscle cramps, fasciculations and distal sensory impairment, mostly (but not exclusively) in individuals (and their descendents) from the Okinawa region in Japan. Absent deep tendon reflexes, elevated creatine kinase levels and autosomal dominant inheritance are also characteristic.","definition_xrefs":["Orphanet:90117"],"direct_ancestors":[{"relation_name":"is_a","term_name":"motor peripheral neuropathy","termid":"MONDO:0002316"},{"relation_name":"is_a","term_name":"hereditary peripheral neuropathy","termid":"MONDO:0020127"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0005244"],"is_obsolete":false,"name":"hereditary motor and sensory neuropathy, Okinawa type","secondary_identifiers":["UMLS:C1858338","MEDGEN:346886","OMIM:604484","GARD:10131","MESH:C535717"],"synonyms":[{"name":"HMSNO","type":"related"},{"name":"HMSNP","type":"exact"},{"name":"hereditary motor and sensory neuropathy, proximal type","type":"exact"},{"name":"hereditary motor and sensory neuropathy, proximal type, formerly","type":"related"},{"name":"neuropathy, hereditary motor and sensory, Okinawa type","type":"related"}],"termid":"MONDO:0011468","xrefs":{"Monarch":{"xref_id":"0011468"}}}


id: PR:O60087
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- meu17 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O60087"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glucoamylase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC14C8.05c","synonyms":[{"name":"1,4-alpha-D-glucan glucohydrolase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-meu17","type":"exact"},{"name":"glucan 1,4-alpha-glucosidase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"meiotic expression up-regulated protein 17 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O60087"}


id: GO:0003300
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division.","definition_xrefs":["GOC:mtg_heart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"striated muscle hypertrophy","termid":"GO:0014897"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cardiac muscle hypertrophy","termid":"GO:0003300"}


id: GO:0052737
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: a ubiquinone + H2O + pyruvate = a ubiquinol + acetate + CO2.","definition_xrefs":["EC:1.2.5.1"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the aldehyde or oxo group of donors, with a quinone or similar compound as acceptor","termid":"GO:0052738"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"pyruvate dehydrogenase (quinone) activity","secondary_identifiers":["KEGG_REACTION:R03145","MetaCyc:RXN-11496","RHEA:27405"],"synonyms":[{"name":"pyruvate dehydrogenase activity","type":"broad"},{"name":"pyruvate:ubiquinone oxidoreductase activity","type":"exact"},{"name":"pyruvate:ubiquinone-8-oxidoreductase activity","type":"related"},{"name":"pyruvic dehydrogenase activity","type":"broad"}],"termid":"GO:0052737"}


id: PBO:0017572
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SUMO activating enzyme E1-type Rad31","termid":"PBO:0017572"}


id: MOD:01312
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces a lysine N6-hydrogen with a quaternary amine reagent heavy (+6amu) form group.","definition_xrefs":["Unimod:62#K","PubMed:11857757"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified L-lysine residue","termid":"MOD:00912"},{"relation_name":"is_a","term_name":"isotope tagged reagent derivatized residue","termid":"MOD:01426"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"quaternary amine labeling reagent heavy form (+6amu) N6-L-lysine","synonyms":[{"name":"GIST-Quat:2H(6)","type":"related"},{"name":"Quaternary amine labeling reagent heavy form (+6amu), N-term & K","type":"related"}],"termid":"MOD:01312"}


id: PR:Q09763
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- gef1 gene.","definition_xrefs":["UniProtKB:Q09763","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"rho guanine nucleotide exchange factor gef1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC24H6.09","synonyms":[{"name":"Spom972h-gef1","type":"exact"}],"termid":"PR:Q09763"}


id: PBO:0080620
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WD repeat domain 59","termid":"PBO:0080620"}


id: GO:2000912
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of galactoglucomannan catabolic process.","definition_xrefs":["GOC:mengo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of polysaccharide metabolic process","termid":"GO:0032881"},{"relation_name":"is_a","term_name":"regulation of carbohydrate catabolic process","termid":"GO:0043470"},{"relation_name":"regulates","term_name":"galactoglucomannan catabolic process","termid":"GO:2000885"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0005975","GO:0008150"],"is_obsolete":false,"name":"regulation of galactoglucomannan catabolic process","synonyms":[{"name":"regulation of galactoglucomannan catabolism","type":"exact"}],"termid":"GO:2000912"}


id: MONDO:0008220
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete pepsinogen 3, group 1 (obsolete MONDO:0008220)","secondary_identifiers":["OMIM:169710"],"synonyms":[{"name":"PGA3","type":"related"},{"name":"pepsinogen 3, Group type 1","type":"exact"},{"name":"pepsinogen 3, group I","type":"related"},{"name":"pepsinogen I--second locus","type":"related"}],"termid":"MONDO:0008220","xrefs":{"Monarch":{"xref_id":"0008220"}}}


id: PBO:0067558
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 711, pseudogene","termid":"PBO:0067558"}


id: GO:0060397
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.","definition_xrefs":["GOC:BHF","GOC:dph","PMID:11445442"],"direct_ancestors":[{"relation_name":"is_a","term_name":"growth hormone receptor signaling pathway","termid":"GO:0060396"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"growth hormone receptor signaling pathway via JAK-STAT","secondary_identifiers":["Reactome:R-HSA-982772"],"synonyms":[{"name":"JAK-STAT cascade involved in growth hormone signalling pathway","type":"exact"}],"termid":"GO:0060397"}


id: MONDO:0007565
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Brooke-Spiegler syndrome","termid":"MONDO:0011512"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426"],"is_obsolete":false,"name":"familial cylindromatosis","secondary_identifiers":["MESH:C536611","NCIT:C43352","OMIM:132700","MEDGEN:343593","GARD:9707","Orphanet:211","UMLS:C1851526"],"synonyms":[{"name":"'turban tumor' syndrome","type":"related"},{"name":"Ancell-Spiegler Cylindromas","type":"related"},{"name":"Ancell-Spiegler syndrome","type":"exact"},{"name":"CYLD","type":"related"},{"name":"Cylindromas, dermal eccrine","type":"related"},{"name":"cylindromatosis, familial","type":"related"},{"name":"turban tumor","type":"exact"},{"name":"turban tumor syndrome","type":"exact"},{"name":"turban tumors","type":"related"},{"name":"turban tumour","type":"exact"},{"name":"turban tumour syndrome","type":"exact"},{"name":"turban tumours","type":"related"}],"termid":"MONDO:0007565","xrefs":{"Monarch":{"xref_id":"0007565"}}}


id: PBO:0001502
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA ligase Trl1 (predicted)","termid":"PBO:0001502"}


id: GO:0141084
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"An intracellular signal transduction pathway that starts with a ligand binding to a pattern recognition receptor (PRR), assembly of the inflammasome complex, leading to the activation of CASP1 and inducing an inflammatory response. In some cases, inflammasome-mediated signal transduction can lead to programmed cell death, such as pyroptosis.","definition_xrefs":["PMID:35883561"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytoplasmic pattern recognition receptor signaling pathway","termid":"GO:0002753"},{"relation_name":"part_of","term_name":"inflammatory response","termid":"GO:0006954"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"inflammasome-mediated signaling pathway","synonyms":[{"name":"inflammasome-mediated signal transduction","type":"exact"}],"termid":"GO:0141084"}


id: SO:0001012
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A DNA sequence with catalytic activity.","definition_xrefs":["SO:cb"],"direct_ancestors":[{"relation_name":"has_quality","term_name":"enzymatic","termid":"SO:0001185"},{"relation_name":"is_a","term_name":"oligo","termid":"SO:0000696"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNAzyme","synonyms":[{"name":"DNA enzyme","type":"exact"},{"name":"catalytic DNA","type":"exact"},{"name":"deoxyribozyme","type":"related"}],"termid":"SO:0001012"}


id: PBO:0030874
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_amino_acid_import_during_vegetative_growth","termid":"PBO:0030874"}


id: GO:0045824
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of response to biotic stimulus","termid":"GO:0002832"},{"relation_name":"is_a","term_name":"negative regulation of defense response","termid":"GO:0031348"},{"relation_name":"is_a","term_name":"negative regulation of response to external stimulus","termid":"GO:0032102"},{"relation_name":"is_a","term_name":"regulation of innate immune response","termid":"GO:0045088"},{"relation_name":"is_a","term_name":"negative regulation of immune response","termid":"GO:0050777"},{"relation_name":"negatively_regulates","term_name":"innate immune response","termid":"GO:0045087"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of innate immune response","synonyms":[{"name":"down regulation of innate immune response","type":"exact"},{"name":"down-regulation of innate immune response","type":"exact"},{"name":"downregulation of innate immune response","type":"exact"},{"name":"inhibition of innate immune response","type":"narrow"}],"termid":"GO:0045824"}


id: MONDO:1010639
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Factor XII deficiency that occurs in dog.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"factor XII deficiency, non-human animal","termid":"MONDO:1010074"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"factor XII deficiency, dog","secondary_identifiers":["OMIA:000364-9615"],"termid":"MONDO:1010639","xrefs":{"Monarch":{"xref_id":"1010639"}}}


id: GO:0016462
data:
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id: GO:0075099
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of protein kinase-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:pamgo_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete modulation by host of symbiont protein kinase-mediated signal transduction (obsolete GO:0075099)","termid":"GO:0075099"}


id: PBO:0001420
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GTPase Ypt3","termid":"PBO:0001420"}


id: PBO:0117101
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BCAT1 divergent transcript","termid":"PBO:0117101"}


id: GO:0035748
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The region of the myelin sheath furthest from the axon.","definition_xrefs":["GOC:BHF","PMID:20237282"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"myelin sheath","termid":"GO:0043209"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"myelin sheath abaxonal region","termid":"GO:0035748"}


id: PBO:0043220
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"clathrin binding box of aftiphilin containing 1","termid":"PBO:0043220"}


id: MONDO:1012934
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any hearing loss that occurs in dogs due to a mutation in the EPS8L2 gene.","definition_xrefs":["MONDO:patterns/nonhuman_disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hearing loss disorder, non-human animal","termid":"MONDO:1012969"},{"relation_name":"is_a","term_name":"inherited auditory system disease, non-human animal","termid":"MONDO:1012970"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"deafness, EPS8L2-related, dog","secondary_identifiers":["OMIA:002550-9615"],"termid":"MONDO:1012934","xrefs":{"Monarch":{"xref_id":"1012934"}}}


id: GO:0030495
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chlorophyll catabolic process","termid":"GO:0015996"},{"relation_name":"is_a","term_name":"bacteriochlorophyll metabolic process","termid":"GO:0030493"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0033013"}],"interesting_parent_ids":["GO:0033013","GO:0008150"],"is_obsolete":false,"name":"bacteriochlorophyll catabolic process","synonyms":[{"name":"bacteriochlorophyll breakdown","type":"exact"},{"name":"bacteriochlorophyll catabolism","type":"exact"},{"name":"bacteriochlorophyll degradation","type":"exact"}],"termid":"GO:0030495"}


id: SO:0000537
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"12 or 23 nucleotide spacer between the V-heptamer and the V-nonamer of a V-gene recombination feature of an immunoglobulin/T-cell receptor gene.","direct_ancestors":[{"relation_name":"is_a","term_name":"vertebrate_immune_system_gene_recombination_spacer","termid":"SO:0000563"},{"relation_name":"part_of","term_name":"V_gene_recombination_feature","termid":"SO:0000538"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"V_spacer","synonyms":[{"name":"V spacer","type":"exact"},{"name":"V-SPACER","type":"exact"}],"termid":"SO:0000537"}


id: GO:0009632
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete freezing tolerance (obsolete GO:0009632)","synonyms":[{"name":"freezing tolerance","type":"exact"}],"termid":"GO:0009632"}


id: GO:0055026
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development.","definition_xrefs":["GOC:vk"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of striated muscle tissue development","termid":"GO:0045843"},{"relation_name":"is_a","term_name":"regulation of cardiac muscle tissue development","termid":"GO:0055024"},{"relation_name":"negatively_regulates","term_name":"cardiac muscle tissue development","termid":"GO:0048738"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of cardiac muscle tissue development","synonyms":[{"name":"down regulation of cardiac muscle development","type":"exact"},{"name":"down-regulation of cardiac muscle development","type":"exact"},{"name":"downregulation of cardiac muscle development","type":"exact"},{"name":"inhibition of cardiac muscle development","type":"narrow"},{"name":"negative regulation of heart muscle development","type":"exact"}],"termid":"GO:0055026"}


id: MONDO:0014155
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any familial atrial fibrillation in which the cause of the disease is a mutation in the SCN1B gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"familial atrial fibrillation","termid":"MONDO:0018054"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"atrial fibrillation, familial, 13","secondary_identifiers":["UMLS:C3809311","GARD:15954","MEDGEN:815641","OMIM:615377"],"synonyms":[{"name":"ATFB13","type":"related"},{"name":"SCN1B familial atrial fibrillation","type":"exact"},{"name":"atrial fibrillation, familial, 13","type":"exact"},{"name":"atrial fibrillation, familial, type 13","type":"exact"},{"name":"familial atrial fibrillation caused by mutation in SCN1B","type":"exact"}],"termid":"MONDO:0014155","xrefs":{"Monarch":{"xref_id":"0014155"}}}


id: MONDO:0021163
data:
  {"annotated_genes":["SJAG_01144","SJAG_00440","SJAG_03677","SJAG_02231","SJAG_03787"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88982],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014937"},{"annotations":[87947],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0003789"},{"annotations":[88573,88574,88575],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007763"}]},"cv_name":"mondo","definition":"A benign or malignant neoplasm affecting the kidney. Representative examples of benign renal neoplasms include fibroma, lipoma, oncocytoma, and juxtaglomerular cell tumor. Representative examples of malignant renal neoplasms include renal cell carcinoma, renal pelvis carcinoma, Wilms tumor, rhabdoid tumor, sarcoma, and lymphoma.","definition_xrefs":["NCIT:C3150"],"direct_ancestors":[{"relation_name":"is_a","term_name":"kidney disorder","termid":"MONDO:0005240"},{"relation_name":"is_a","term_name":"urinary system neoplasm","termid":"MONDO:0021066"}],"gene_count":5,"genes_by_uniquename":{"SJAG_00440":null,"SJAG_01144":null,"SJAG_02231":null,"SJAG_03677":null,"SJAG_03787":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240"],"is_obsolete":false,"name":"kidney neoplasm","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["SCTID:126880001","MEDGEN:5967","ONCOTREE:KIDNEY","EFO:0003865","UMLS:C0022665","ICD9:239.5"],"synonyms":[{"name":"kidney neoplasm","type":"exact"},{"name":"kidney neoplasm (disease)","type":"exact"},{"name":"kidney tumor","type":"exact"},{"name":"kidney tumour","type":"exact"},{"name":"neoplasm of kidney","type":"exact"},{"name":"neoplasm of the kidney","type":"exact"},{"name":"renal neoplasm","type":"exact"},{"name":"renal tumor","type":"exact"},{"name":"renal tumors","type":"exact"},{"name":"renal tumour","type":"exact"},{"name":"renal tumours","type":"exact"},{"name":"tumor of kidney","type":"exact"},{"name":"tumor of the kidney","type":"exact"},{"name":"tumour of kidney","type":"exact"},{"name":"tumour of the kidney","type":"exact"}],"termid":"MONDO:0021163","terms_by_termid":{"MONDO:0003789":null,"MONDO:0007763":null,"MONDO:0014937":null},"xrefs":{"Monarch":{"xref_id":"0021163"}}}


id: PBO:0080556
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WW domain binding protein 2","termid":"PBO:0080556"}


id: FYPO:0006217
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the border of the nuclear and nucleolar regions is increased.","definition_xrefs":["PomBase:mah","PMID:16251348"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein localization to nucleolus","termid":"FYPO:0003687"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000138"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0001320","FYPO:0000002","FYPO:0000138","FYPO:0005447"],"is_obsolete":false,"name":"increased protein localization to nucleolar periphery","synonyms":[{"name":"increased protein localisation to nucleolar periphery","type":"exact"},{"name":"increased protein localization to nucleolar periphery during mitotic cell cycle","type":"related"},{"name":"increased protein localization to nucleolar periphery during vegetative growth","type":"exact"}],"termid":"FYPO:0006217"}


id: GO:0102332
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: malonyl-CoA + H+ + a long-chain acyl-[acp] + a reduced electron acceptor = 2 carbon dioxide + coenzyme A + a terminal olefin + a holo-[acyl-carrier protein] + an oxidized electron acceptor.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete fatty-acyl-[acp] elongase/decarboxylase activity (obsolete GO:0102332)","termid":"GO:0102332"}


id: GO:0004479
data:
  {"annotated_genes":["SJAG_01368"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[79975],"is_not":false,"summary":null,"term":"GO:0004479"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: 10-formyltetrahydrofolate + L-methionyl-tRNA + H2O = tetrahydrofolate + N-formylmethionyl-tRNA.","definition_xrefs":["EC:2.1.2.9"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydroxymethyl-, formyl- and related transferase activity","termid":"GO:0016742"},{"relation_name":"is_a","term_name":"catalytic activity, acting on a tRNA","termid":"GO:0140101"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01368":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0140101"}],"interesting_parent_ids":["GO:0016741","GO:0003824","GO:0140101","GO:0016740","GO:0140098","GO:0003674"],"is_obsolete":false,"name":"methionyl-tRNA formyltransferase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["RHEA:24380","Reactome:R-HSA-5389841","MetaCyc:METHIONYL-TRNA-FORMYLTRANSFERASE-RXN","GO:0001718","GO:0070128"],"synonyms":[{"name":"10-formyltetrahydrofolate:L-methionyl-tRNA N-formyltransferase activity","type":"related"},{"name":"N(10)-formyltetrahydrofolic-methionyl-transfer ribonucleic transformylase activity","type":"related"},{"name":"N-terminal peptidyl-methionine N-formylation","type":"related"},{"name":"N10-formyltetrahydrofolic-methionyl-transfer ribonucleic transformylase activity","type":"related"},{"name":"conversion of met-tRNAf to fmet-tRNA","type":"related"},{"name":"conversion of mitochondrial met-tRNAf to fmet-tRNA","type":"related"},{"name":"formylmethionyl-transfer ribonucleic synthetase activity","type":"related"},{"name":"methionyl ribonucleic formyltransferase activity","type":"related"},{"name":"methionyl-tRNA Met formyltransferase activity","type":"related"},{"name":"methionyl-tRNA transformylase activity","type":"related"},{"name":"methionyl-transfer RNA transformylase activity","type":"related"},{"name":"methionyl-transfer ribonucleate methyltransferase activity","type":"related"},{"name":"methionyl-transfer ribonucleic transformylase activity","type":"related"},{"name":"mitochondrial N-terminal peptidyl-methionine N-formylation","type":"related"}],"termid":"GO:0004479","terms_by_termid":{"GO:0004479":null}}


id: PBO:0072633
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"arginine and serine rich protein 1","termid":"PBO:0072633"}


id: PBO:0082625
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of both the SWI/SNF and RSC chromatin remodeling complexes; suggested role in chromosome maintenance; possible weak regulator of Ty1 transposition; protein abundance increases in response to DNA replication stress","termid":"PBO:0082625"}


id: MONDO:0015639
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Benign partial epilepsy with secondarily generalized seizures in infancy is a rare infantile epilepsy syndrome characterized by seizures presenting with motion arrest and staring. They are followed by generalized tonic-clonic convulsions with normal interictal EEG and focal paroxysmal discharges, followed by generalization in ictal EEG. Seizures usually occur in clusters and are responsive to treatment. Psychomotor development is normal.","definition_xrefs":["Orphanet:166302"],"direct_ancestors":[{"relation_name":"is_a","term_name":"benign non-familial infantile seizures","termid":"MONDO:0015637"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027"],"is_obsolete":false,"name":"benign partial epilepsy with secondarily generalized seizures in infancy","secondary_identifiers":["GARD:20073","MEDGEN:1656339","icd11.foundation:413225821","UMLS:C4749728"],"termid":"MONDO:0015639","xrefs":{"Monarch":{"xref_id":"0015639"}}}


id: PBO:0049301
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glutathione S-transferase mu 3 pseudogene 1","termid":"PBO:0049301"}


id: PBO:0017725
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Partner Of Spa2","termid":"PBO:0017725"}


id: PBO:0047536
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fibroblast growth factor 2","termid":"PBO:0047536"}


id: PBO:0065393
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PSMA1 pseudogene 1","termid":"PBO:0065393"}


id: GO:0043297
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The formation of an apical junction, a functional unit located near the cell apex at the points of contact between epithelial cells composed of the tight junction, the zonula adherens junction and the desmosomes, by the aggregation, arrangement and bonding together of its constituents.","definition_xrefs":["PMID:14729475","PMID:15196556","GOC:go_curators","PMID:10854689"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell-cell junction assembly","termid":"GO:0007043"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0044085"],"is_obsolete":false,"name":"apical junction assembly","synonyms":[{"name":"apical junction complex assembly","type":"exact"}],"termid":"GO:0043297"}


id: GO:0018916
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving nitrobenzene (nitrobenzol), a derivative of benzene with an NO2 group attached to the ring. It is a yellow aromatic liquid used in perfumery and manufactured in large quantities in the preparation of aniline.","definition_xrefs":["GOC:curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"benzene-containing compound metabolic process","termid":"GO:0042537"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"nitrobenzene metabolic process","secondary_identifiers":["UM-BBD_pathwayID:nb"],"synonyms":[{"name":"nitrobenzene metabolism","type":"exact"}],"termid":"GO:0018916"}


id: GO:0000253
data:
  {"annotated_genes":["SJAG_03235"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[72663],"is_not":false,"summary":null,"term":"GO:0000253"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: a 3-betahydroxyl sterol + NADP+ = a 3-oxosterol sterol + NADPH + H+.","definition_xrefs":["PMID:9811880","EC:1.1.1.270","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0033764"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03235":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["Reactome:R-HSA-194632","MetaCyc:RXN-13686","Reactome:R-HSA-194689","RHEA:34787","GO:0050576"],"synonyms":[{"name":"3-KSR activity","type":"related"},{"name":"3-keto sterol reductase activity","type":"exact"},{"name":"3-keto-steroid reductase activity","type":"exact"},{"name":"3beta-hydroxy-steroid:NADP+ 3-oxidoreductase","type":"related"}],"termid":"GO:0000253","terms_by_termid":{"GO:0000253":null}}


id: PBO:0067994
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 296","termid":"PBO:0067994"}


id: PBO:0002364
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"translation elongation factor EF-1 alpha Ef1a-b","termid":"PBO:0002364"}


id: GO:1990031
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"Dense plexus formed by the descending collaterals of cerebellar basket cells that wrap around a Purkinje cell axonal initial segment.","definition_xrefs":["NIF_Subcellular:sao109906988"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"axon","termid":"GO:0030424"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"pinceau fiber","termid":"GO:1990031"}


id: GO:0010016
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of the shoot are generated and organized. The shoot is the part of a seed plant body that is usually above ground.","definition_xrefs":["ISBN:0877797099","GOC:sm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure morphogenesis","termid":"GO:0009653"},{"relation_name":"part_of","term_name":"shoot system development","termid":"GO:0048367"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"shoot system morphogenesis","synonyms":[{"name":"shoot morphogenesis","type":"exact"}],"termid":"GO:0010016"}


id: GO:0032596
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of a protein into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein transport within lipid bilayer","termid":"GO:0032594"},{"relation_name":"is_a","term_name":"establishment of protein localization to membrane","termid":"GO:0090150"},{"relation_name":"is_a","term_name":"protein localization to membrane raft","termid":"GO:1903044"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0061024"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0051179","GO:0061024","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"protein transport into membrane raft","synonyms":[{"name":"protein translocation into membrane raft","type":"exact"},{"name":"protein transport into lipid raft","type":"exact"},{"name":"receptor translocation into membrane raft","type":"narrow"},{"name":"receptor transport into membrane raft","type":"narrow"}],"termid":"GO:0032596"}


id: PBO:0084653
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Minor isoform of tropomyosin; binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; appears to have distinct and also overlapping functions with Tpm1p; TPM2 has a paralog, TPM1, that arose from the whole genome duplication","termid":"PBO:0084653"}


id: PBO:0076818
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"teneurin transmembrane protein 4","termid":"PBO:0076818"}


id: PBO:0085567
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein essential for meiotic DNA replication and sporulation; cytoplasmic protein; subunit of the MIS complex which controls mRNA methylation during during the induction of sporulation; also interacts with Orc2p, which is a component of the origin recognition complex","termid":"PBO:0085567"}


id: PBO:0076812
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TEN1-CDK3 readthrough (NMD candidate)","termid":"PBO:0076812"}


id: PBO:0053229
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leucine rich repeat containing G protein-coupled receptor 5","termid":"PBO:0053229"}


id: SO:1000182
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A kind of chromosome variation where the chromosome complement is not an exact multiple of the haploid number.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chromosome_variation","termid":"SO:0000240"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome_number_variation","synonyms":[{"name":"Jannovar:chromosome_number_variation","type":"exact"},{"name":"chromosome number variation","type":"exact"}],"termid":"SO:1000182"}


id: GO:0008332
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transmembrane transfer of a calcium ion by a low voltage-gated channel. A low voltage-gated channel is a channel whose open state is dependent on low voltage across the membrane in which it is embedded.","definition_xrefs":["PMID:16382099","GOC:mtg_transport","ISBN:0815340729"],"direct_ancestors":[{"relation_name":"is_a","term_name":"voltage-gated calcium channel activity","termid":"GO:0005245"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0022857","GO:0005215","GO:0003674"],"is_obsolete":false,"name":"low voltage-gated calcium channel activity","synonyms":[{"name":"T-type calcium channel","type":"related"},{"name":"low voltage gated calcium channel activity","type":"exact"},{"name":"low voltage-dependent calcium channel activity","type":"exact"}],"termid":"GO:0008332"}


id: PBO:0068599
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U2 small nuclear 50, pseudogene","termid":"PBO:0068599"}


id: MONDO:0004054
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"acute inflammation of lacrimal passage","termid":"MONDO:0004055"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"acute canaliculitis","secondary_identifiers":["ICD9:375.31","DOID:6969","SCTID:84399007","UMLS:C0339130","MEDGEN:572974","ICD10CM:H04.33"],"synonyms":[{"name":"acute canaliculitis, lacrimal","type":"exact"},{"name":"acute lacrimal canaliculitis","type":"exact"}],"termid":"MONDO:0004054","xrefs":{"Monarch":{"xref_id":"0004054"}}}


id: PBO:0045868
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"eukaryotic translation elongation factor 1 beta 2 pseudogene 1","termid":"PBO:0045868"}


id: SO:0000727
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A regulatory region where transcription factor binding sites are clustered to regulate various aspects of transcription activities. (CRMs can be located a few kb to hundreds of kb upstream of the core promoter, in the coding sequence, within introns, or in the untranslated regions (UTR) sequences, and even on a different chromosome). A single gene can be regulated by multiple CRMs to give precise control of its spatial and temporal expression. CRMs function as nodes in large, intertwined regulatory network. CRM DNA accessibility is subject to regulation by dbTFs and transcription co-TFs.","definition_xrefs":["SO:SG","PMID:19660565"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transcriptional_cis_regulatory_region","termid":"SO:0001055"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cis_regulatory_module","synonyms":[{"name":"CRM","type":"exact"},{"name":"TF module","type":"exact"},{"name":"cis regulatory module","type":"exact"},{"name":"transcription factor module","type":"exact"}],"termid":"SO:0000727"}


id: GO:0051093
data:
  {"annotated_genes":["SJAG_00304","SJAG_04203","SJAG_02169","SJAG_04140","SJAG_00855"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[113051],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0075297"},{"annotations":[92537],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051517"},{"annotations":[118162],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0090258"},{"annotations":[108286,103864],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010637"}]},"cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of biological process","termid":"GO:0048519"},{"relation_name":"is_a","term_name":"regulation of developmental process","termid":"GO:0050793"},{"relation_name":"negatively_regulates","term_name":"developmental process","termid":"GO:0032502"}],"gene_count":5,"genes_by_uniquename":{"SJAG_00304":null,"SJAG_00855":null,"SJAG_02169":null,"SJAG_04140":null,"SJAG_04203":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of developmental process","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"down regulation of developmental process","type":"exact"},{"name":"down-regulation of developmental process","type":"exact"},{"name":"downregulation of developmental process","type":"exact"},{"name":"inhibition of developmental process","type":"narrow"}],"termid":"GO:0051093","terms_by_termid":{"GO:0010637":null,"GO:0051517":null,"GO:0075297":null,"GO:0090258":null}}


id: PBO:0083906
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Flavin-linked sulfhydryl oxidase localized to the ER lumen; involved in disulfide bond formation within the endoplasmic reticulum (ER)","termid":"PBO:0083906"}


id: MONDO:0035122
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GRIN2B-related developmental delay, intellectual disability and autism spectrum disorder","secondary_identifiers":["GARD:22356","MEDGEN:1830118","Orphanet:589547","UMLS:C5681638"],"termid":"MONDO:0035122","xrefs":{"Monarch":{"xref_id":"0035122"}}}


id: GO:0030061
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"Any of the inward folds of the mitochondrial inner membrane. Their number, extent, and shape differ in mitochondria from different tissues and organisms. They appear to be devices for increasing the surface area of the mitochondrial inner membrane, where the enzymes of electron transport and oxidative phosphorylation are found. Their shape can vary with the respiratory state of the mitochondria.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"mitochondrial inner membrane","termid":"GO:0005743"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005739"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0005737","GO:0005575","GO:0005739"],"is_obsolete":false,"name":"mitochondrial crista","secondary_identifiers":["NIF_Subcellular:sao333328131"],"synonyms":[{"name":"cristae","type":"broad"},{"name":"mitochondrial cristae","type":"exact"}],"termid":"GO:0030061"}


id: GO:0072341
data:
  {"annotated_genes":["SJAG_04031","SJAG_03170","SJAG_00869","SJAG_04077","SJAG_01351","SJAG_00053","SJAG_05181","SJAG_02572"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[101087,72202],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0043295"},{"annotations":[106202,89808,92227,104246],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0001786"},{"annotations":[65993,59629],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031177"}]},"cv_name":"molecular_function","definition":"Binding to a modified amino acid.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"binding","termid":"GO:0005488"}],"gene_count":8,"genes_by_uniquename":{"SJAG_00053":null,"SJAG_00869":null,"SJAG_01351":null,"SJAG_02572":null,"SJAG_03170":null,"SJAG_04031":null,"SJAG_04077":null,"SJAG_05181":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0003674","GO:0005488"],"is_obsolete":false,"name":"modified amino acid binding","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"amino acid derivative binding","type":"exact"}],"termid":"GO:0072341","terms_by_termid":{"GO:0001786":null,"GO:0031177":null,"GO:0043295":null}}


id: MONDO:0020355
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"coloboma","termid":"MONDO:0001476"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"coloboma of eye lens","secondary_identifiers":["GARD:1433","icd11.foundation:1368271881","MEDGEN:451043","Orphanet:98943","UMLS:C0344516"],"termid":"MONDO:0020355","xrefs":{"Monarch":{"xref_id":"0020355"}}}


id: GO:1990108
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A protein deubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is removed from a protein.","definition_xrefs":["PMID:23708998"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein deubiquitination","termid":"GO:0016579"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0070647"}],"interesting_parent_ids":["GO:0070647","GO:0008150"],"is_obsolete":false,"name":"protein linear deubiquitination","termid":"GO:1990108"}


id: GO:0045465
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized cell acquires the specialized features of the R8 photoreceptor.","definition_xrefs":["PMID:11880339"],"direct_ancestors":[{"relation_name":"is_a","term_name":"compound eye photoreceptor cell differentiation","termid":"GO:0001751"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"R8 cell differentiation","termid":"GO:0045465"}


id: FYPO:0007620
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal when the cell is subject to oxidative stress.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased protein phosphorylation during vegetative growth","termid":"FYPO:0001838"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002494"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0002494","FYPO:0005447","FYPO:0000002","FYPO:0001320","FYPO:0002274"],"is_obsolete":false,"name":"decreased protein phosphorylation during cellular response to oxidative stress","synonyms":[{"name":"decreased protein phosphorylation during cellular response to oxidative stress during mitotic cell cycle","type":"related"},{"name":"decreased protein phosphorylation during cellular response to oxidative stress during vegetative growth","type":"exact"},{"name":"decreased protein phosphorylation during oxidative stress response","type":"exact"},{"name":"reduced protein phosphorylation during cellular response to oxidative stress","type":"exact"}],"termid":"FYPO:0007620"}


id: PBO:0013800
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"adenosine deaminase Ada1","termid":"PBO:0013800"}


id: MONDO:0007900
data:
  {"annotated_genes":["SJAG_00321"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88253],"is_not":false,"summary":null,"term":"MONDO:0007900"}]},"cv_name":"mondo","definition":"Any inherited isolated nail anomaly in which the cause of the disease is a mutation in the PLCD1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"pachyonychia congenita","termid":"MONDO:0016471"},{"relation_name":"is_a","term_name":"inherited isolated nail anomaly","termid":"MONDO:0019284"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00321":null},"genotype_count":0,"is_obsolete":false,"name":"nonsyndromic congenital nail disorder 3","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MESH:C537289","UMLS:C0544855","MEDGEN:107463","GARD:2555","OMIM:151600","SCTID:74102009","DOID:0080081","ICD9:703.8"],"synonyms":[{"name":"Gorlin Bushkell Jensen syndrome","type":"related"},{"name":"NDNC3","type":"related"},{"name":"PLCD1 inherited isolated nail anomaly","type":"exact"},{"name":"inherited isolated nail anomaly caused by mutation in PLCD1","type":"exact"},{"name":"leukonychia Striatus","type":"related"},{"name":"leukonychia punctata","type":"related"},{"name":"leukonychia totalis and/or partialis","type":"related"},{"name":"leukonychia totalis multiple sebaceous cysts renal calculi","type":"related"},{"name":"nail disorder, nonsyndromic congenital, 3","type":"related"},{"name":"nail disorder, nonsyndromic congenital, 3, (leukonychia)","type":"exact"},{"name":"nail disorder, nonsyndromic congenital, type 3","type":"exact"},{"name":"nonsyndromic congenital nail disorder type 3","type":"exact"},{"name":"porcelain nails","type":"related"}],"termid":"MONDO:0007900","terms_by_termid":{"MONDO:0007900":null},"xrefs":{"Monarch":{"xref_id":"0007900"}}}


id: PBO:0049556
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"H2B clustered histone 18","termid":"PBO:0049556"}


id: PBO:0110874
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNAJ (Hsp40) chaperone family protein","termid":"PBO:0110874"}


id: SO:0000424
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"The U3 segment of the long terminal repeats.","direct_ancestors":[{"relation_name":"is_a","term_name":"LTR_component","termid":"SO:0000848"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"U3_LTR_region","synonyms":[{"name":"U3 LTR region","type":"exact"},{"name":"U3 long terminal repeat region","type":"exact"}],"termid":"SO:0000424"}


id: FYPO:0000878
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromere inner repeat regions occurs to a lower extent than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal histone H3-K9 dimethylation at centromere inner repeat during vegetative growth","termid":"FYPO:0000868"},{"relation_name":"is_a","term_name":"decreased histone H3-K9 dimethylation at centromere during vegetative growth","termid":"FYPO:0000877"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0002494","FYPO:0001985","FYPO:0002274","FYPO:0001320","FYPO:0005447","FYPO:0000002"],"is_obsolete":false,"name":"decreased histone H3-K9 dimethylation at centromere inner repeat during vegetative growth","synonyms":[{"name":"decreased histone H3 K9 dimethylation at centromere inner repeat during vegetative growth","type":"exact"},{"name":"decreased histone H3-K9 dimethylation at centromere imr during vegetative growth","type":"exact"},{"name":"decreased histone H3-K9 dimethylation at centromere inner repeat during mitotic cell cycle","type":"related"},{"name":"decreased histone H3-K9 dimethylation at centromere inner repeat region during vegetative growth","type":"exact"},{"name":"decreased histone H3K9 dimethylation at centromere inner repeat during vegetative growth","type":"exact"},{"name":"decreased histone H3K9me2 at centromere inner repeat during vegetative growth","type":"exact"},{"name":"reduced histone H3-K9 dimethylation at centromere inner repeat during vegetative growth","type":"exact"},{"name":"v histone lysine H3 K9 dimethylation at centromere inner repeat during vegetative growth","type":"exact"}],"termid":"FYPO:0000878"}


id: PBO:0083035
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase; required for biosynthesis of isopentenyladenosine in mitochondrial and cytoplasmic tRNAs; also has a role in tRNA gene-mediated silencing; gene encodes two isozymic forms; converts to a prion form, prion conversion contributes to azole antifungal resistance by upregulating ergosterol biosynthesis; homolog of human TRIT1, a mutation in which is associated with severe combined respiratory chain defects","termid":"PBO:0083035"}


id: GO:0050645
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: UDP-glucose + limonin = glucosyl-limonin + UDP.","definition_xrefs":["EC:2.4.1.210"],"direct_ancestors":[{"relation_name":"is_a","term_name":"UDP-glucosyltransferase activity","termid":"GO:0035251"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016757"}],"interesting_parent_ids":["GO:0003824","GO:0016740","GO:0016757","GO:0003674"],"is_obsolete":false,"name":"limonoid glucosyltransferase activity","secondary_identifiers":["RHEA:11256","MetaCyc:2.4.1.210-RXN"],"synonyms":[{"name":"LGTase activity","type":"related"},{"name":"limonoid UDP-glucosyltransferase activity","type":"related"},{"name":"uridine diphosphoglucose-limonoid glucosyltransferase activity","type":"related"}],"termid":"GO:0050645"}


id: GO:0019343
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate cystathionine.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cysteine biosynthetic process","termid":"GO:0019344"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006790"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0006520"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006790","GO:0006520","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"cysteine biosynthetic process via cystathionine","synonyms":[{"name":"cysteine anabolism via cystathionine","type":"exact"},{"name":"cysteine formation via cystathionine","type":"exact"},{"name":"cysteine synthesis via cystathionine","type":"exact"}],"termid":"GO:0019343"}


id: PBO:0029531
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_protein_localization_to_septum","termid":"PBO:0029531"}


id: PBO:0088899
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Fen1 family nuclease, XP-G family","termid":"PBO:0088899"}


id: PBO:0076807
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tektin 5","termid":"PBO:0076807"}


id: GO:0080036
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of cytokinin signaling.","definition_xrefs":["GOC:dhl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of signal transduction","termid":"GO:0009966"},{"relation_name":"regulates","term_name":"cytokinin-activated signaling pathway","termid":"GO:0009736"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"regulation of cytokinin-activated signaling pathway","synonyms":[{"name":"regulation of cytokinin mediated signaling pathway","type":"related"},{"name":"regulation of cytokinin mediated signalling","type":"exact"}],"termid":"GO:0080036"}


id: PBO:0077001
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"THAP domain containing 12 pseudogene 3","termid":"PBO:0077001"}


id: GO:0043309
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of eosinophil degranulation.","definition_xrefs":["ISBN:0781735149"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of myeloid leukocyte mediated immunity","termid":"GO:0002886"},{"relation_name":"is_a","term_name":"regulation of leukocyte degranulation","termid":"GO:0043300"},{"relation_name":"is_a","term_name":"regulation of immune response","termid":"GO:0050776"},{"relation_name":"regulates","term_name":"eosinophil degranulation","termid":"GO:0043308"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0016192"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810","GO:0016192"],"is_obsolete":false,"name":"regulation of eosinophil degranulation","synonyms":[{"name":"regulation of eosinophil granule exocytosis","type":"exact"}],"termid":"GO:0043309"}


id: MONDO:0004471
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"The inflammation of one or more joints caused by a bacterial infection within the joint space. Symptoms include pain, stiffness, and decreased range of motion in the affected joint.","definition_xrefs":["NCIT:C26699"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bacterial infectious disease","termid":"MONDO:0005113"},{"relation_name":"is_a","term_name":"infective arthritis","termid":"MONDO:0042485"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bacterial arthritis","secondary_identifiers":["EFO:1001351","ICD9:711.97","ICD9:711.93","ICD9:711.0","ICD9:711.9","ICD9:711.91","ICD9:711.90","ICD9:711.95","SCTID:48245008","UMLS:C1692886","NANDO:2200437","ICD9:711.92","MESH:D001170","ICD9:711.40","DOID:813","MEDGEN:308434","ICD9:711.94","ICD9:711.96"],"synonyms":[{"name":"infectious arthritis","type":"broad"},{"name":"pyogenic arthritis","type":"exact"},{"name":"septic arthritis","type":"exact"}],"termid":"MONDO:0004471","xrefs":{"Monarch":{"xref_id":"0004471"}}}


id: PBO:0038636
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acyl-CoA thioesterase 1","termid":"PBO:0038636"}


id: GO:0140204
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of pyridoxal from outside of a cell, across the plasma membrane and into the cytosol.","definition_xrefs":["GOC:vw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"import across plasma membrane","termid":"GO:0098739"},{"relation_name":"is_a","term_name":"pyridoxal transmembrane transport","termid":"GO:1903090"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0055085","GO:0006810","GO:0008150","GO:0051179"],"is_obsolete":false,"name":"pyridoxal import across plasma membrane","termid":"GO:0140204"}


id: PBO:0078904
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Gln (anticodon CTG) 13-1","termid":"PBO:0078904"}


id: PBO:0004066
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glutamine-fructose-6-phosphate transaminase (predicted)","termid":"PBO:0004066"}


id: PBO:0066581
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RAD9-HUS1-RAD1 interacting nuclear orphan 1","termid":"PBO:0066581"}


id: PBO:0034577
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-aggregated_actin_cortical_patches","termid":"PBO:0034577"}


id: MONDO:0007608
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A desmoid tumor (DT) is a benign, locally invasive soft tissue tumor associated with a high recurrence rate but with no metastatic potential.","definition_xrefs":["Orphanet:873"],"direct_ancestors":[{"relation_name":"is_a","term_name":"fibromatosis","termid":"MONDO:0005031"},{"relation_name":"is_a","term_name":"soft tissue neoplasm","termid":"MONDO:0006424"},{"relation_name":"is_a","term_name":"hereditary disorder of connective tissue","termid":"MONDO:0023603"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"desmoid tumor","secondary_identifiers":["EFO:0009907","GARD:1820","ICDO:8821/1","MEDGEN:38187","NORD:1049","NCIT:C9182","ONCOTREE:DES","DOID:0080366","UMLS:C0079218","OMIM:135290"],"synonyms":[{"name":"FIF","type":"related"},{"name":"aggressive fibromatosis","type":"exact"},{"name":"deep fibromatosis","type":"exact"},{"name":"deep fibromatosis/desmoid tumor","type":"exact"},{"name":"deep fibromatosis/desmoid tumour","type":"exact"},{"name":"desmoid disease, hereditary","type":"related"},{"name":"desmoid disorder, hereditary","type":"related"},{"name":"desmoid fibromatosis","type":"exact"},{"name":"desmoid tumor","type":"exact"},{"name":"desmoid type fibromatosis","type":"exact"},{"name":"desmoid-type fibromatosis","type":"exact"},{"name":"desmoid/aggressive fibromatosis","type":"related"},{"name":"familial infiltrative fibromatosis","type":"related"},{"name":"fibromatosis, familial infiltrative","type":"related"}],"termid":"MONDO:0007608","xrefs":{"Monarch":{"xref_id":"0007608"}}}


id: PBO:0061454
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nuclear receptor subfamily 5 group A member 2","termid":"PBO:0061454"}


id: GO:0055016
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the hypochord over time, from its formation to the mature structure. The hypochord is a transient rod-like structure in the embryos of fish, lampreys and amphibians that is located immediately ventral to the notochord. The hypochord may play a role in positioning the dorsal aorta.","definition_xrefs":["GOC:lb","GOC:devbiol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tissue development","termid":"GO:0009888"},{"relation_name":"is_a","term_name":"embryonic organ development","termid":"GO:0048568"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"hypochord development","synonyms":[{"name":"subnotochordal rod development","type":"exact"}],"termid":"GO:0055016"}


id: PBO:0031407
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-spheroid_vegetative_cell","termid":"PBO:0031407"}


id: GO:1990549
data:
  {"annotated_genes":["SJAG_04328"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[94718],"is_not":false,"summary":null,"term":"GO:1990549"}]},"cv_name":"biological_process","definition":"The process in which NAD is transported across a mitochondrial membrane, into or out of the mitochondrion.","definition_xrefs":["PMID:16291748"],"direct_ancestors":[{"relation_name":"is_a","term_name":"NAD transmembrane transport","termid":"GO:0035352"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04328":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0055085"}],"interesting_parent_ids":["GO:0008150","GO:0006810","GO:0051179","GO:0055085"],"is_obsolete":false,"name":"mitochondrial NAD transmembrane transport","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:1990549","terms_by_termid":{"GO:1990549":null}}


id: PBO:0089733
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"histone lysine methyltransferase Set6","termid":"PBO:0089733"}


id: GO:0019271
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of the hydroxamate iron transport compound aerobactin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aerobactin (C22H36N4O13) is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid.","definition_xrefs":["GOC:ai","PMID:23192658"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tricarboxylic acid transport","termid":"GO:0006842"},{"relation_name":"is_a","term_name":"modified amino acid transport","termid":"GO:0072337"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0008150","GO:0051179","GO:0006810"],"is_obsolete":false,"name":"aerobactin transport","termid":"GO:0019271"}


id: GO:0106408
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2 ATP = 3',3'-c-di-AMP + 2 diphosphate.","definition_xrefs":["RHEA:35655","PMID:30884174"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleotidyltransferase activity","termid":"GO:0016779"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016779"}],"interesting_parent_ids":["GO:0016779","GO:0003824","GO:0003674","GO:0016740"],"is_obsolete":false,"name":"diadenylate cyclase activity","secondary_identifiers":["EC:2.7.7.85","MetaCyc:RXN-14338"],"synonyms":[{"name":"cyclic-di-AMP synthase","type":"exact"}],"termid":"GO:0106408"}


id: MONDO:0002993
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A neuroendocrine tumor arising from the delta cells of the pancreas. It is characterized by inappropriate secretion of somatostatin and associated with diabetes mellitus, hypochlorhydria, gallbladder disease, diarrhea, steatorrhea, anemia, and weight loss.","definition_xrefs":["NCIT:C95595"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pancreatic delta cell neuroendocrine tumor","termid":"MONDO:0002994"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"pancreatic somatostatinoma","secondary_identifiers":["MEDGEN:235079","UMLS:C1368041","DOID:4432"],"synonyms":[{"name":"pancreatic delta cell somatostatin producing neoplasm","type":"exact"},{"name":"pancreatic somatostatin cell tumor","type":"exact"},{"name":"pancreatic somatostatin cell tumour","type":"exact"}],"termid":"MONDO:0002993","xrefs":{"Monarch":{"xref_id":"0002993"}}}


id: MONDO:0011397
data:
  {"annotated_genes":["SJAG_02119"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88591],"is_not":false,"summary":null,"term":"MONDO:0011397"}]},"cv_name":"mondo","definition":"Autosomal dominant cerebellar ataxia, deafness and narcolepsy (ADCA-DN) is a polymorphic disorder and a subtype of autosomal dominant cerebellar ataxia type 1 (ADCA type 1) characterized by ataxia, sensorineural deafness and narcolepsy with cataplexy and dementia.","definition_xrefs":["Orphanet:314404"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sleep-wake disorder","termid":"MONDO:0003406"},{"relation_name":"is_a","term_name":"autosomal dominant cerebellar ataxia type I","termid":"MONDO:0019792"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02119":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0002039"},{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0000426","MONDO:0002039","MONDO:0005559"],"is_obsolete":false,"name":"autosomal dominant cerebellar ataxia, deafness and narcolepsy","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C3807295","DOID:0050968","GARD:12372","MEDGEN:813625","OMIM:604121"],"synonyms":[{"name":"ADCA-DN","type":"related"},{"name":"ADCA-DN syndrome","type":"exact"},{"name":"ADCADN","type":"related"},{"name":"autosomal dominant cerebellar ataxia, deafness and narcolepsy","type":"exact"},{"name":"autosomal dominant cerebellar ataxia, deafness, and narcolepsy","type":"related"},{"name":"autosomal dominant cerebellar ataxia-deafness-narcolepsy syndrome","type":"related"},{"name":"cerebellar ataxia, deafness, and narcolepsy, autosomal dominant","type":"related"}],"termid":"MONDO:0011397","terms_by_termid":{"MONDO:0011397":null},"xrefs":{"Monarch":{"xref_id":"0011397"}}}


id: MONDO:0002348
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete chondrodysplasia punctata (obsolete MONDO:0002348)","termid":"MONDO:0002348","xrefs":{"Monarch":{"xref_id":"0002348"}}}


id: PBO:0048855
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"golgin A2","termid":"PBO:0048855"}


id: GO:0072495
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A class of nuclear body in the eukaryotic host cell, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA. The host is the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:rph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"host cell nuclear part","termid":"GO:0044094"},{"relation_name":"part_of","term_name":"host cell nucleoplasm","termid":"GO:0044095"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"host cell Cajal body","synonyms":[{"name":"coiled body of host","type":"exact"},{"name":"host cell coiled body","type":"exact"}],"termid":"GO:0072495"}


id: GO:0030201
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving heparan sulfate proteoglycans, which consist of a core protein linked to a heparan sulfate glycosaminoglycan. The heparan sulfate chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-alpha-(1,4)-hexuronic acid, the former being either sulfated or deacetylated on its amino group as well as sulfated on one of its hydroxyl groups, and the latter being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids.","definition_xrefs":["PMID:27241222"],"direct_ancestors":[{"relation_name":"is_a","term_name":"proteoglycan metabolic process","termid":"GO:0006029"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"heparan sulfate proteoglycan metabolic process","synonyms":[{"name":"heparan sulfate proteoglycan metabolism","type":"exact"},{"name":"heparan sulphate proteoglycan metabolic process","type":"exact"},{"name":"heparan sulphate proteoglycan metabolism","type":"exact"},{"name":"heparin proteoglycan metabolic process","type":"related"}],"termid":"GO:0030201"}


id: PBO:0076357
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"synaptotagmin like 4","termid":"PBO:0076357"}


id: PBO:0039614
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annexin A2 pseudogene 1","termid":"PBO:0039614"}


id: GO:0140723
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of patulin, an acetate-derived tetraketide mycotoxin produced by several fungal species that shows antimicrobial properties against several bacteria.","definition_xrefs":["PMID:30680886","PMID:25120234"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polyketide biosynthetic process","termid":"GO:0030639"},{"relation_name":"is_a","term_name":"mycotoxin biosynthetic process","termid":"GO:0043386"},{"relation_name":"is_a","term_name":"alcohol biosynthetic process","termid":"GO:0046165"},{"relation_name":"is_a","term_name":"lactone biosynthetic process","termid":"GO:1901336"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0019748"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0019748","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"patulin biosynthetic process","synonyms":[{"name":"patulin anabolism","type":"exact"},{"name":"patulin biosynthesis","type":"exact"},{"name":"patulin formation","type":"exact"},{"name":"patulin synthesis","type":"exact"}],"termid":"GO:0140723"}


id: PBO:0059838
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial fission regulator 2","termid":"PBO:0059838"}


id: GO:0140024
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of an endosome towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an endosome to a microtubule, and ends when the endosome reaches its final destination.","definition_xrefs":["PMID:25706234","PMID:24803650"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plus-end-directed vesicle transport along microtubule","termid":"GO:0072383"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0051179","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"plus-end-directed endosome transport along mitotic spindle midzone microtubule","termid":"GO:0140024"}


id: PBO:0048880
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"golgin A6 family member F, pseudogene","termid":"PBO:0048880"}


id: GO:0031270
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The myosin-based contraction and retraction of a pseudopodium.","definition_xrefs":["GOC:pg"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular component disassembly","termid":"GO:0022411"},{"relation_name":"is_a","term_name":"pseudopodium organization","termid":"GO:0031268"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"pseudopodium retraction","termid":"GO:0031270"}


id: GO:0102622
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: linuron + H2O = N,O-dimethylhydroxylamine + carbon dioxide + 3,4-dichloroaniline.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete linuron hydrolase activity (obsolete GO:0102622)","termid":"GO:0102622"}


id: MONDO:1011042
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hereditary lightly pigmented coat, lips and nose and blue eyes in dogs due to a variation in the OCA2 gene.","definition_xrefs":["PMID:28973042"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oculocutaneous albinism, non-human animal","termid":"MONDO:1012579"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"oculocutaneous albinism, OCA2-related, dog","secondary_identifiers":["OMIA:002130-9615"],"termid":"MONDO:1011042","xrefs":{"Monarch":{"xref_id":"1011042"}}}


id: GO:1903794
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to cortisol.","definition_xrefs":["PMID:18483153","GOC:mr","GO_REF:0000067","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"alcohol binding","termid":"GO:0043178"},{"relation_name":"is_a","term_name":"steroid hormone binding","termid":"GO:1990239"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0008289"}],"interesting_parent_ids":["GO:0005488","GO:0008289","GO:0003674"],"is_obsolete":false,"name":"cortisol binding","termid":"GO:1903794"}


id: PBO:0071489
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L32 pseudogene 30","termid":"PBO:0071489"}


id: PBO:0043714
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome c oxidase subunit 6B1 pseudogene 2","termid":"PBO:0043714"}


id: PBO:0045501
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"desmoglein 4","termid":"PBO:0045501"}


id: GO:0051134
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell activation.","definition_xrefs":["PMID:9133426","ISBN:0781735149","PMID:12154375"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of alpha-beta T cell activation","termid":"GO:0046636"},{"relation_name":"is_a","term_name":"regulation of NK T cell activation","termid":"GO:0051133"},{"relation_name":"negatively_regulates","term_name":"NK T cell activation","termid":"GO:0051132"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0007155"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0007155"}],"interesting_parent_ids":["GO:0007155","GO:0008150"],"is_obsolete":false,"name":"negative regulation of NK T cell activation","synonyms":[{"name":"down regulation of NK T cell activation","type":"exact"},{"name":"down-regulation of NK T cell activation","type":"exact"},{"name":"downregulation of NK T cell activation","type":"exact"},{"name":"inhibition of NK T cell activation","type":"narrow"},{"name":"negative regulation of NK T lymphocyte activation","type":"exact"},{"name":"negative regulation of NK T-cell activation","type":"exact"},{"name":"negative regulation of NK T-lymphocyte activation","type":"exact"},{"name":"negative regulation of NKT cell activation","type":"exact"},{"name":"negative regulation of NT cell activation","type":"exact"},{"name":"negative regulation of natural T cell activation","type":"exact"},{"name":"negative regulation of natural killer T cell activation","type":"exact"}],"termid":"GO:0051134"}


id: PBO:0060600
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"non-SMC condensin II complex subunit G2","termid":"PBO:0060600"}


id: GO:0031829
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a type 4 serotonin receptor.","definition_xrefs":["GOC:nln","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G protein-coupled serotonin receptor binding","termid":"GO:0031821"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0005488","GO:0003674","GO:0005515"],"is_obsolete":false,"name":"type 4 serotonin receptor binding","synonyms":[{"name":"5-hydroxytryptamine 4 receptor binding","type":"exact"},{"name":"type 4 serotonin receptor ligand","type":"narrow"}],"termid":"GO:0031829"}


id: GO:0051167
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving D-xylulose 5-phosphate, a derivative of the ketopentose xylulose phosphorylated at the 5 carbon; it is an intermediate in the pentose phosphate pathway.","definition_xrefs":["ISBN:0721662544"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphate-containing compound metabolic process","termid":"GO:0006796"},{"relation_name":"is_a","term_name":"organophosphate metabolic process","termid":"GO:0019637"},{"relation_name":"is_a","term_name":"carbohydrate derivative metabolic process","termid":"GO:1901135"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"D-xylulose 5-phosphate metabolic process","synonyms":[{"name":"D-xylulose 5-phosphate metabolism","type":"exact"},{"name":"D-xylulose-5-phosphate metabolic process","type":"exact"},{"name":"D-xylulose-5-phosphate metabolism","type":"exact"},{"name":"xylulose 5-phosphate metabolic process","type":"exact"},{"name":"xylulose 5-phosphate metabolism","type":"exact"},{"name":"xylulose-5-phosphate metabolic process","type":"exact"},{"name":"xylulose-5-phosphate metabolism","type":"exact"}],"termid":"GO:0051167"}


id: MONDO:0009178
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"epidermolysis bullosa dystrophica","termid":"MONDO:0006543"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"epidermolysis bullosa dystrophica Neurotrophica","secondary_identifiers":["SCTID:254176007","UMLS:C0268368","OMIM:226500","MESH:C562637","ICD9:757.39","MEDGEN:78666"],"synonyms":[{"name":"epidermolysis bullosa dystrophica Neurotrophica","type":"exact"},{"name":"epidermolysis bullosa progressiva, recessive","type":"related"},{"name":"epidermolysis bullosa with congenital deafness","type":"related"}],"termid":"MONDO:0009178","xrefs":{"Monarch":{"xref_id":"0009178"}}}


id: GO:1902352
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of filamentous growth of a population of unicellular organisms in response to starvation.","definition_xrefs":["GOC:TermGenie","PMID:23223039","GOC:rn"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of filamentous growth of a population of unicellular organisms in response to starvation by negative regulation of transcription from RNA polymerase II promoter (obsolete GO:1902352)","termid":"GO:1902352"}


id: MONDO:0017113
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Isolated bilateral hemispheric cerebellar hypoplasia is a rare cerebellar malformation characterized by hypoplasia of both cerebellar hemispheres with no other cerebellar/cerebral anomaly or other associated clinical feature. Affected patients present with mild hypotonia with motor delay, mild cognitive impairment, language delay, visuospatial and verbal memory deficits, dysdiadochokinesis, intentional tremor, and possible presence of emotional fragility and mild depression.","definition_xrefs":["Orphanet:269221"],"direct_ancestors":[{"relation_name":"is_a","term_name":"central nervous system malformation","termid":"MONDO:0020022"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0020022"}],"interesting_parent_ids":["MONDO:0020022"],"is_obsolete":false,"name":"isolated bilateral hemispheric cerebellar hypoplasia","secondary_identifiers":["UMLS:C4749791","icd11.foundation:1366151963","GARD:20996","MEDGEN:1657026"],"termid":"MONDO:0017113","xrefs":{"Monarch":{"xref_id":"0017113"}}}


id: GO:2000567
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of memory T cell activation.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of T cell activation","termid":"GO:0050863"},{"relation_name":"regulates","term_name":"memory T cell activation","termid":"GO:0035709"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of memory T cell activation","termid":"GO:2000567"}


id: PBO:0085802
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein of unknown function; copurifies with late Golgi vesicles containing the v-SNARE Tlg2p; PTM1 has a paralog, YHL017W, that arose from the whole genome duplication","termid":"PBO:0085802"}


id: PR:Q9UU88
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An adenylate kinase isoenzyme 6 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR12595:SF0","PRO:DNx","OMA:SCHPO04983"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"adenylate kinase isoenzyme 6 homolog (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC830.11c","secondary_identifiers":["UniProtKB:Q9UU88"],"synonyms":[{"name":"AK/ATPase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"AK6 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-AK6","type":"exact"},{"name":"dual activity adenylate kinase/ATPase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9UU88"}


id: PBO:0082775
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of the SSU and 90S preribosomes; involved in pre-18S rRNA processing; binds to U3 snoRNA and Mpp10p; multicopy suppressor of sensitivity to Brefeldin A; expression is induced during lag phase and also by cold shock","termid":"PBO:0082775"}


id: GO:2001219
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of S/G2 transition of mitotic cell cycle.","definition_xrefs":["GOC:mtg_cell_cycle","GOC:obol"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of S/G2 transition of mitotic cell cycle (obsolete GO:2001219)","synonyms":[{"name":"positive regulation of S/G2 transition of mitotic cell cycle","type":"exact"}],"termid":"GO:2001219"}


id: GO:0034888
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: endosulfan + O2 + 2 H+ + 2 e- = endosulfan sulfate + H2O.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete endosulfan monooxygenase I activity (obsolete GO:0034888)","termid":"GO:0034888"}


id: MONDO:1011822
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"cancer or benign tumor, non-human animal","termid":"MONDO:1011305"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"squamous cell carcinoma of the digit, non-human animal","secondary_identifiers":["OMIA:001787"],"termid":"MONDO:1011822","xrefs":{"Monarch":{"xref_id":"1011822"}}}


id: GO:0015129
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of lactate from one side of a membrane to the other. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices.","definition_xrefs":["GOC:ai","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monocarboxylic acid transmembrane transporter activity","termid":"GO:0008028"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005215","GO:0003674","GO:0022857"],"is_obsolete":false,"name":"lactate transmembrane transporter activity","secondary_identifiers":["Reactome:R-HSA-373867","Reactome:R-HSA-373875"],"synonyms":[{"name":"monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity","type":"related"}],"termid":"GO:0015129"}


id: MONDO:0013551
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any hereditary spastic paraplegia in which the cause of the disease is a mutation in the AP4B1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary spastic paraplegia","termid":"MONDO:0019064"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"hereditary spastic paraplegia 47","secondary_identifiers":["MEDGEN:481368","DOID:0110799","GARD:15749","NORD:1993","NCIT:C164224","OMIM:614066","UMLS:C3279738"],"synonyms":[{"name":"AP4B1 hereditary spastic paraplegia","type":"exact"},{"name":"CPSQ5","type":"exact"},{"name":"SPG47","type":"exact"},{"name":"Spastic Paraplegia 47","type":"exact"},{"name":"autosomal recessive spastic paraplegia 47","type":"exact"},{"name":"cerebral palsy, spastic quadriplegic, 5","type":"related"},{"name":"cerebral palsy, spastic quadriplegic, 5, formerly","type":"related"},{"name":"hereditary spastic paraplegia 47","type":"exact"},{"name":"hereditary spastic paraplegia caused by mutation in AP4B1","type":"exact"},{"name":"hereditary spastic paraplegia type 47","type":"exact"},{"name":"spastic paraplegia 47, autosomal recessive","type":"related"},{"name":"spastic quadriplegic cerebral palsy 5","type":"exact"}],"termid":"MONDO:0013551","xrefs":{"Monarch":{"xref_id":"0013551"}}}


id: PBO:0059517
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1","termid":"PBO:0059517"}


id: PBO:0001477
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heat shock protein Ssa1 (predicted)","termid":"PBO:0001477"}


id: MONDO:0023019
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dwarfism bluish sclerae","termid":"MONDO:0023019","xrefs":{"Monarch":{"xref_id":"0023019"}}}


id: PBO:0067483
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 617, pseudogene","termid":"PBO:0067483"}


id: PBO:0060765
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADH:ubiquinone oxidoreductase subunit B4 pseudogene 9","termid":"PBO:0060765"}


id: PBO:0120245
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pig-B, dol-P-Man:Man(2)GlcN-acyl-PI alpha-1,2-mannosyltransferase","termid":"PBO:0120245"}


id: PBO:0042292
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CD3 epsilon subunit of T-cell receptor complex","termid":"PBO:0042292"}


id: GO:0044877
data:
  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id: MONDO:0012746
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A dilated cardiomyopathy that has material basis in mutation in the TNNI3 gene on chromosome 19q13.","definition_xrefs":["DOID:0110460","PMID:15070570"],"direct_ancestors":[{"relation_name":"is_a","term_name":"familial isolated dilated cardiomyopathy","termid":"MONDO:0700335"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"dilated cardiomyopathy 2A","secondary_identifiers":["GARD:15532","OMIM:611880","UMLS:C2678474","MEDGEN:437214"],"synonyms":[{"name":"CMD2A","type":"exact"},{"name":"cardiomyopathy, congestive, autosomal recessive","type":"related"},{"name":"cardiomyopathy, dilated, 2A","type":"related"},{"name":"cardiomyopathy, dilated, autosomal recessive","type":"related"},{"name":"cardiomyopathy, dilated, type 2A","type":"exact"},{"name":"dilated cardiomyopathy type 2A","type":"exact"}],"termid":"MONDO:0012746","xrefs":{"Monarch":{"xref_id":"0012746"}}}


id: MONDO:0044225
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  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete creatine kinase, brain type, ectopic expression of (obsolete MONDO:0044225)","secondary_identifiers":["HGNC:1992"],"synonyms":[{"name":"CKBE","type":"related"},{"name":"creatine KINASE, brain type, ectopic expression OF","type":"related"}],"termid":"MONDO:0044225","xrefs":{"Monarch":{"xref_id":"0044225"}}}


id: MONDO:0006889
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A condition in which the foreskin of an uncircumcised male is retracted and cannot be pulled back over the glans penis. It results in painful swelling of the glans penis and, if is not corrected, may lead to gangrene.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phimosis","termid":"MONDO:0006904"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"paraphimosis","secondary_identifiers":["EFO:1001086","MEDGEN:14611","ICD10CM:N47.2","NCIT:C34893","icd11.foundation:452889019","MESH:D010263","UMLS:C0030483","SCTID:13758004","MedDRA:10033890","DOID:5334"],"termid":"MONDO:0006889","xrefs":{"Monarch":{"xref_id":"0006889"}}}


id: MONDO:0034943
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  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete isolated vitreoretinopathy (obsolete MONDO:0034943)","secondary_identifiers":["Orphanet:519304"],"termid":"MONDO:0034943","xrefs":{"Monarch":{"xref_id":"0034943"}}}


id: PBO:0029902
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  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_chromatin_silencing","termid":"PBO:0029902"}


id: SO:0001645
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  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A measurable sequence feature that varies within a population.","definition_xrefs":["SO:db"],"direct_ancestors":[{"relation_name":"is_a","term_name":"biological_region","termid":"SO:0001411"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"genetic_marker","synonyms":[{"name":"genetic marker","type":"related"}],"termid":"SO:0001645"}


id: PBO:0067053
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 74, pseudogene","termid":"PBO:0067053"}


id: SO:0000144
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  {"annotation_feature_type":"gene","cv_name":"sequence","gene_count":0,"genotype_count":0,"name":"OBSOLETE SO:0000144 primary_transcript_attribute (obsolete SO:0000144)","termid":"SO:0000144"}


id: MONDO:0859295
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  {"annotated_genes":["SJAG_02467"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87554],"is_not":false,"summary":null,"term":"MONDO:0859295"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Mendelian neurodevelopmental disorder","termid":"MONDO:0100500"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02467":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0700092"}],"interesting_parent_ids":["MONDO:0700092"],"is_obsolete":false,"name":"neurodevelopmental disorder with short stature, prominent forehead, and feeding difficulties","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1824001","OMIM:620070","UMLS:C5774228","DOID:0070479"],"termid":"MONDO:0859295","terms_by_termid":{"MONDO:0859295":null},"xrefs":{"Monarch":{"xref_id":"0859295"}}}


id: PBO:0062278
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 5 subfamily H member 14","termid":"PBO:0062278"}


id: PBO:0066456
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"REXO1 like 9, pseudogene","termid":"PBO:0066456"}


id: GO:0032998
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex composed of an Fc-epsilon RI alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-episilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgE.","definition_xrefs":["GOC:add","ISBN:0781735149"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Fc receptor complex","termid":"GO:0032997"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005886"}],"interesting_parent_ids":["GO:0032991","GO:0005886","GO:0005575"],"is_obsolete":false,"name":"Fc-epsilon receptor I complex","synonyms":[{"name":"FceRI complex","type":"exact"},{"name":"IgE receptor complex","type":"broad"},{"name":"immunoglobulin E receptor complex","type":"broad"}],"termid":"GO:0032998"}


id: PBO:0089415
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ER membrane protein complex subunit Emc2/TPR repeat protein Oca3","termid":"PBO:0089415"}


id: PBO:0120167
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Adapter protein for pexophagy and the Cvt targeting pathway; directs receptor-bound cargo to the phagophore assembly site (PAS) for packaging into vesicles; required for recruiting other proteins to the PAS; recruits Dnm1p to facilitate fission of mitochondria that are destined for removal by mitophagy; dynamic association with the daughter (old) SPB is involved in microtubule-mediated chromosome segregation","termid":"PBO:0120167"}


id: FYPO:0002982
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of serine residues in one or more specific proteins, or of specific protein sites, does not occur.","definition_xrefs":["PomBase:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete abolished protein serine phosphorylation during vegetative growth (obsolete FYPO:0002982)","synonyms":[{"name":"abolished peptidyl-serine phosphorylation during vegetative growth","type":"exact"},{"name":"abolished protein serine phosphorylation during mitotic cell cycle","type":"related"},{"name":"protein serine phosphorylation abolished during vegetative growth","type":"exact"}],"termid":"FYPO:0002982"}


id: MONDO:0006986
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An enlarged thyroid gland with at least 50% of the gland situated behind the sternum. It is an unusual presentation of an intrathoracic goiter. Substernal goiters frequently cause compression on the trachea leading to deviation, narrowing, and respiratory symptoms.","definition_xrefs":["MESH:D006045"],"direct_ancestors":[{"relation_name":"is_a","term_name":"goiter","termid":"MONDO:0005397"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"substernal goiter","secondary_identifiers":["MEDGEN:9066","DOID:13200","UMLS:C0018024","SCTID:66392007"],"synonyms":[{"name":"retrosternal thyroid goiter","type":"exact"},{"name":"retrosternal thyroid goitre","type":"exact"}],"termid":"MONDO:0006986","xrefs":{"Monarch":{"xref_id":"0006986"}}}


id: PBO:0003657
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase family or domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CDK family kinase","termid":"PBO:0003657"}


id: MONDO:0007555
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A basal subtype of epidermolysis bullosa simplex (EBS) characterized by sometimes widespread, primarily acral blistering.","definition_xrefs":["Orphanet:79401"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epidermolysis bullosa simplex","termid":"MONDO:0017610"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"epidermolysis bullosa simplex 5A, Ogna type","secondary_identifiers":["MESH:C535962","DOID:0060736","ICD9:757.39","GARD:2148","OMIM:131950","UMLS:C0432317","MEDGEN:98488","SCTID:398071000"],"synonyms":[{"name":"EBS-O","type":"exact"},{"name":"EBS-Og","type":"exact"},{"name":"EBSOG","type":"exact"},{"name":"epidermolysis bullosa simplex 5A, Ogna type","type":"exact"},{"name":"epidermolysis bullosa simplex, Ogna type","type":"exact"}],"termid":"MONDO:0007555","xrefs":{"Monarch":{"xref_id":"0007555"}}}


id: GO:1903415
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of flavonoid from endoplasmic reticulum to plant-type vacuole.","definition_xrefs":["GOC:TermGenie","PMID:25116949","GO_REF:0000078","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transport","termid":"GO:0006810"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810","GO:0051179"],"is_obsolete":false,"name":"flavonoid transport from endoplasmic reticulum to plant-type vacuole","synonyms":[{"name":"flavonoid accumulation in vacuole","type":"related"}],"termid":"GO:1903415"}


id: PBO:0039952
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"arkadia (RNF111) C-terminal like ring finger ubiquitin ligase 2C","termid":"PBO:0039952"}


id: PBO:0005807
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin-protein ligase E3 Brl1","termid":"PBO:0005807"}


id: GO:0043715
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2,3-diketo-5-methylthiopentyl-1-phosphate = H+ + 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate. 2,3-diketo-5-methylthiopentyl-1-phosphate is also known as DK-MTP-1-P, and 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate as HK-MTPenyl-1-P.","definition_xrefs":["MetaCyc:R82-RXN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intramolecular oxidoreductase activity, interconverting keto- and enol-groups","termid":"GO:0016862"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016853"}],"interesting_parent_ids":["GO:0003674","GO:0016853","GO:0003824"],"is_obsolete":false,"name":"2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity","secondary_identifiers":["EC:5.3.2.5","RHEA:18769"],"synonyms":[{"name":"DK-MTP-1-P enolase activity","type":"exact"},{"name":"E-1","type":"related"},{"name":"MasA","type":"related"},{"name":"mtnW","type":"related"}],"termid":"GO:0043715"}


id: PBO:0028795
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_chromatin_binding_at_mating-type_region_replication_fork_barrier","termid":"PBO:0028795"}


id: GO:0000740
data:
  {"annotated_genes":["SJAG_00810"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[80389],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0048288"}]},"cv_name":"biological_process","definition":"The joining of 2 or more lipid bilayer membranes that surround the nucleus.","definition_xrefs":["GOC:elh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nuclear membrane organization","termid":"GO:0071763"},{"relation_name":"is_a","term_name":"organelle membrane fusion","termid":"GO:0090174"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00810":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0061024"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0061024"}],"interesting_parent_ids":["GO:0061024","GO:0008150"],"is_obsolete":false,"name":"nuclear membrane fusion","references_by_uniquename":{"GO_REF:0000033":null},"termid":"GO:0000740","terms_by_termid":{"GO:0048288":null}}


id: GO:1900144
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of BMP secretion.","definition_xrefs":["GOC:TermGenie","GOC:sart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cell communication","termid":"GO:0010647"},{"relation_name":"is_a","term_name":"positive regulation of signaling","termid":"GO:0023056"},{"relation_name":"is_a","term_name":"positive regulation of protein secretion","termid":"GO:0050714"},{"relation_name":"is_a","term_name":"regulation of BMP secretion","termid":"GO:2001284"},{"relation_name":"positively_regulates","term_name":"BMP secretion","termid":"GO:0038055"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"positively_regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0006810","GO:0023052"],"is_obsolete":false,"name":"positive regulation of BMP secretion","synonyms":[{"name":"activation of BMP protein secretion","type":"narrow"},{"name":"activation of BMP secretion","type":"narrow"},{"name":"activation of bone morphogenetic protein secretion","type":"narrow"},{"name":"positive regulation of BMP protein secretion","type":"exact"},{"name":"positive regulation of bone morphogenetic protein secretion","type":"exact"},{"name":"up regulation of BMP protein secretion","type":"exact"},{"name":"up regulation of BMP secretion","type":"exact"},{"name":"up regulation of bone morphogenetic protein secretion","type":"exact"},{"name":"up-regulation of BMP protein secretion","type":"exact"},{"name":"up-regulation of BMP secretion","type":"exact"},{"name":"up-regulation of bone morphogenetic protein secretion","type":"exact"},{"name":"upregulation of BMP protein secretion","type":"exact"},{"name":"upregulation of BMP secretion","type":"exact"},{"name":"upregulation of bone morphogenetic protein secretion","type":"exact"}],"termid":"GO:1900144"}


id: PBO:0083893
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FG-nucleoporin component of central core of the nuclear pore complex; contributes directly to nucleocytoplasmic transport and maintenance of the nuclear pore complex (NPC) permeability barrier and is involved in gene tethering at the nuclear periphery; NUP100 has a paralog, NUP116, that arose from the whole genome duplication","termid":"PBO:0083893"}


id: PBO:0028912
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-inviable_elongated_vegetative_cell_with_abnormal_septum","termid":"PBO:0028912"}


id: PBO:0058096
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4312","termid":"PBO:0058096"}


id: GO:1904827
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen sulfide biosynthetic process.","definition_xrefs":["GO_REF:0000058","GOC:BHF","GOC:BHF_miRNA","GOC:rph","GOC:TermGenie","PMID:22034194"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of biosynthetic process","termid":"GO:0009890"},{"relation_name":"is_a","term_name":"negative regulation of sulfur metabolic process","termid":"GO:0051175"},{"relation_name":"is_a","term_name":"regulation of hydrogen sulfide biosynthetic process","termid":"GO:1904826"},{"relation_name":"negatively_regulates","term_name":"hydrogen sulfide biosynthetic process","termid":"GO:0070814"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0006790"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006790"}],"interesting_parent_ids":["GO:0008150","GO:0006790"],"is_obsolete":false,"name":"negative regulation of hydrogen sulfide biosynthetic process","synonyms":[{"name":"down regulation of hydrogen sulfide anabolism","type":"exact"},{"name":"down regulation of hydrogen sulfide biosynthesis","type":"exact"},{"name":"down regulation of hydrogen sulfide biosynthetic process","type":"exact"},{"name":"down regulation of hydrogen sulfide formation","type":"exact"},{"name":"down regulation of hydrogen sulfide synthesis","type":"exact"},{"name":"down regulation of hydrogen sulphide biosynthesis","type":"exact"},{"name":"down regulation of hydrogen sulphide biosynthetic process","type":"exact"},{"name":"down-regulation of hydrogen sulfide anabolism","type":"exact"},{"name":"down-regulation of hydrogen sulfide biosynthesis","type":"exact"},{"name":"down-regulation of hydrogen sulfide biosynthetic process","type":"exact"},{"name":"down-regulation of hydrogen sulfide formation","type":"exact"},{"name":"down-regulation of hydrogen sulfide synthesis","type":"exact"},{"name":"down-regulation of hydrogen sulphide biosynthesis","type":"exact"},{"name":"down-regulation of hydrogen sulphide biosynthetic process","type":"exact"},{"name":"downregulation of hydrogen sulfide anabolism","type":"exact"},{"name":"downregulation of hydrogen sulfide biosynthesis","type":"exact"},{"name":"downregulation of hydrogen sulfide biosynthetic process","type":"exact"},{"name":"downregulation of hydrogen sulfide formation","type":"exact"},{"name":"downregulation of hydrogen sulfide synthesis","type":"exact"},{"name":"downregulation of hydrogen sulphide biosynthesis","type":"exact"},{"name":"downregulation of hydrogen sulphide biosynthetic process","type":"exact"},{"name":"inhibition of hydrogen sulfide anabolism","type":"narrow"},{"name":"inhibition of hydrogen sulfide biosynthesis","type":"narrow"},{"name":"inhibition of hydrogen sulfide biosynthetic process","type":"narrow"},{"name":"inhibition of hydrogen sulfide formation","type":"narrow"},{"name":"inhibition of hydrogen sulfide synthesis","type":"narrow"},{"name":"inhibition of hydrogen sulphide biosynthesis","type":"narrow"},{"name":"inhibition of hydrogen sulphide biosynthetic process","type":"narrow"},{"name":"negative regulation of hydrogen sulfide anabolism","type":"exact"},{"name":"negative regulation of hydrogen sulfide biosynthesis","type":"exact"},{"name":"negative regulation of hydrogen sulfide formation","type":"exact"},{"name":"negative regulation of hydrogen sulfide synthesis","type":"exact"},{"name":"negative regulation of hydrogen sulphide biosynthesis","type":"exact"},{"name":"negative regulation of hydrogen sulphide biosynthetic process","type":"exact"}],"termid":"GO:1904827"}


id: PBO:0061683
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nucleoporin 133","termid":"PBO:0061683"}


id: MONDO:0013181
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any amelogenesis imperfecta in which the cause of the disease is a mutation in the WDR72 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amelogenesis imperfecta type 2","termid":"MONDO:0015048"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"amelogenesis imperfecta hypomaturation type 2A3","secondary_identifiers":["GARD:15630","MESH:C567706","OMIM:613211","MEDGEN:416381","DOID:0110061","UMLS:C2750771"],"synonyms":[{"name":"AI2A3","type":"exact"},{"name":"WDR72 amelogenesis imperfecta","type":"exact"},{"name":"amelogenesis imperfecta caused by mutation in WDR72","type":"exact"},{"name":"amelogenesis imperfecta hypomaturation type 2A3","type":"exact"},{"name":"amelogenesis imperfecta hypomaturation type IIA3","type":"exact"},{"name":"amelogenesis imperfecta type IIA3","type":"exact"},{"name":"amelogenesis imperfecta, hypomaturation type, IIA3","type":"related"},{"name":"amelogenesis imperfecta, type IIA3","type":"exact"}],"termid":"MONDO:0013181","xrefs":{"Monarch":{"xref_id":"0013181"}}}


id: GO:0007493
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The cell fate determination process in which a cell becomes capable of differentiating autonomously into an endoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.","definition_xrefs":["GOC:go_curators","ISBN:0878932437"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell fate determination","termid":"GO:0001709"},{"relation_name":"part_of","term_name":"endodermal cell fate commitment","termid":"GO:0001711"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"endodermal cell fate determination","synonyms":[{"name":"endoderm cell fate determination","type":"exact"}],"termid":"GO:0007493"}


id: MONDO:0002410
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"pyelitis","termid":"MONDO:0006938"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240"],"is_obsolete":false,"name":"pyeloureteritis cystica","secondary_identifiers":["SCTID:37779008","UMLS:C0156254","DOID:2743","ICD10CM:N28.85","ICD9:590.3","MEDGEN:510216"],"termid":"MONDO:0002410","xrefs":{"Monarch":{"xref_id":"0002410"}}}


id: SO:0001919
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A cytosine methylated at the 4 nitrogen.","definition_xrefs":["SO:rtapella"],"direct_ancestors":[{"relation_name":"is_a","term_name":"methylated_cytosine","termid":"SO:0000114"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"4_methylcytosine","secondary_identifiers":["http://www.insdc.org/files/feature_table.html#7.4.2","http:http\\://www.pacificbiosciences.com/pdf/WP_Detecting_DNA_Base_Modifications_Using_SMRT_Sequencing.pdf"],"synonyms":[{"name":"4-mC","type":"exact"},{"name":"4-methylcytosine","type":"exact"},{"name":"N4 methylcytosine","type":"exact"},{"name":"N4-methylcytosine","type":"exact"},{"name":"N4_methylcytosine","type":"exact"},{"name":"m-4C","type":"exact"},{"name":"m4c","type":"exact"}],"termid":"SO:0001919"}


id: MONDO:0003283
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign or malignant neoplasm that affects the epididymis. Representative examples include epididymal adenomatoid tumor and epididymal adenocarcinoma.","definition_xrefs":["NCIT:C39958"],"direct_ancestors":[{"relation_name":"is_a","term_name":"male reproductive system neoplasm","termid":"MONDO:0024582"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"epididymal neoplasm","secondary_identifiers":["SCTID:126902008","ICD9:239.5","DOID:512","MEDGEN:138047","UMLS:C0346239"],"synonyms":[{"name":"epididymal neoplasm","type":"exact"},{"name":"epididymis neoplasm","type":"exact"},{"name":"epididymis neoplasm (disease)","type":"exact"},{"name":"epididymis tumor","type":"exact"},{"name":"epididymis tumour","type":"exact"},{"name":"neoplasm of epididymis","type":"exact"},{"name":"neoplasm of epididymus","type":"exact"},{"name":"tumor of epididymis","type":"exact"},{"name":"tumour of epididymis","type":"exact"}],"termid":"MONDO:0003283","xrefs":{"Monarch":{"xref_id":"0003283"}}}


id: MONDO:0700256
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any type 1 interferonopathies in which the cause of the disease is a variation in the TREX1 gene. Individuals with variants in TREX1 can present with a variety of phenotypes, including Aicardi-Goutieres syndrome, chilblain lupus, or retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations.","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disorder of connective tissue","termid":"MONDO:0023603"},{"relation_name":"is_a","term_name":"type 1 interferonopathy","termid":"MONDO:0700264"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TREX1-related type 1 interferonopathy","termid":"MONDO:0700256","xrefs":{"Monarch":{"xref_id":"0700256"}}}


id: MONDO:0015793
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"multiminicore myopathy","termid":"MONDO:0018948"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"moderate multiminicore disease with hand involvement","secondary_identifiers":["UMLS:C1861753","MEDGEN:396213","Orphanet:178145","GARD:17078"],"termid":"MONDO:0015793","xrefs":{"Monarch":{"xref_id":"0015793"}}}


id: GO:0003796
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the hydrolysis of the beta-(1->4) linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan.","definition_xrefs":["PMID:22748813","EC:3.2.1.17"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, hydrolyzing O-glycosyl compounds","termid":"GO:0004553"},{"relation_name":"is_a","term_name":"peptidoglycan muralytic activity","termid":"GO:0061783"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0016798"}],"interesting_parent_ids":["GO:0016798","GO:0003824","GO:0016787","GO:0003674"],"is_obsolete":false,"name":"lysozyme activity","secondary_identifiers":["MetaCyc:3.2.1.17-RXN","Reactome:R-HSA-8862320"],"synonyms":[{"name":"1,4-N-acetylmuramidase activity","type":"exact"},{"name":"L-7001","type":"related"},{"name":"N,O-diacetylmuramidase activity","type":"exact"},{"name":"PR1-lysozyme","type":"related"},{"name":"globulin G","type":"related"},{"name":"globulin G1","type":"related"},{"name":"lysozyme g","type":"related"},{"name":"mucopeptide N-acetylmuramoylhydrolase activity","type":"exact"},{"name":"mucopeptide glucohydrolase activity","type":"exact"},{"name":"muramidase activity","type":"exact"},{"name":"peptidoglycan N-acetylmuramoylhydrolase activity","type":"related"}],"termid":"GO:0003796"}


id: PBO:0085104
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Nuclear protein that negatively regulates pseudohyphal differentiation; plays a regulatory role in the cyclic AMP (cAMP)-dependent protein kinase (PKA) signal transduction pathway; relocalizes to the cytosol in response to hypoxia; SOK2 has a paralog, PHD1, that arose from the whole genome duplication","termid":"PBO:0085104"}


id: GO:0106060
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of exit from mitosis.","definition_xrefs":["GOC:al","PMID:11493649"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of meiotic cell cycle phase transition","termid":"GO:1901993"},{"relation_name":"regulates","term_name":"exit from meiosis","termid":"GO:1990947"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0007049","GO:0008150"],"is_obsolete":false,"name":"regulation of exit from meiosis","termid":"GO:0106060"}


id: MONDO:0019415
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Fetal and neonatal alloimmune thrombocytopenia (NAIT) is a blood disorder that affects pregnant women and their babies. NAIT was first reported in the literature in 1953 and is estimated to occur in as many as 1 in 1200 live births. NAIT results in the destruction of platelets in the fetus or infant due to a mismatch between the mother's platelets and those of the baby. Certain molecules (antigens) on the surface of the baby's platelets are recognized as foreign by the mother's immune system. The mother's immune system then creates antibodies that attack and destroy the baby's platelets. Though NAIT can occur whenever the mother's blood mixes with that of the baby, it is usually triggered when the mother is exposed to the baby's blood during delivery. Many cases of NAIT are mild. Signs and symptoms may include a low platelet count (thrombocytopenia) and signs of bleeding into the skin such as petechiae and purpura. In the most severe cases, NAIT can cause bleeding episodes that may result in death or long-term disability. Bleeding episodes can occur either during pregnancy or after birth. Management of the infant with neonatal alloimmune thrombocytopenia may include platelet transfusions, ultrasounds, and intravenous immunoglobulin (IVIG). Treatment for pregnant mothers at risk for NAIT may include IVIG and steroids.","direct_ancestors":[{"relation_name":"is_a","term_name":"hemorrhagic disease","termid":"MONDO:0002243"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"fetal and neonatal alloimmune thrombocytopenia","secondary_identifiers":["SCTID:240305000","Orphanet:853","MEDGEN:1720701","UMLS:C3854603","ICD10CM:P61.0","GARD:2295","NORD:91170","NANDO:2200647"],"synonyms":[{"name":"NAIT","type":"exact"}],"termid":"MONDO:0019415","xrefs":{"Monarch":{"xref_id":"0019415"}}}


id: PBO:0091509
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"I:g.3855791delG","termid":"PBO:0091509"}


id: GO:0043087
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the rate of GTP hydrolysis by a GTPase.","definition_xrefs":["GOC:mah","GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of hydrolase activity","termid":"GO:0051336"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of GTPase activity","secondary_identifiers":["GO:0032315","GO:0032317","GO:0043088","GO:0032312","GO:0032319","GO:0032318","GO:0032313","GO:0032314","GO:0032316"],"synonyms":[{"name":"regulation of ARF GTPase activity","type":"narrow"},{"name":"regulation of Cdc42 GTPase activity","type":"narrow"},{"name":"regulation of Rab GTPase activity","type":"narrow"},{"name":"regulation of Rac GTPase activity","type":"narrow"},{"name":"regulation of Ral GTPase activity","type":"narrow"},{"name":"regulation of Ran GTPase activity","type":"narrow"},{"name":"regulation of Rap GTPase activity","type":"narrow"},{"name":"regulation of Ras GTPase activity","type":"narrow"},{"name":"regulation of Rho GTPase activity","type":"narrow"}],"termid":"GO:0043087"}


id: PBO:0046382
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"EOGT divergent transcript","termid":"PBO:0046382"}


id: MONDO:0010093
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"syndesmodysplasic dwarfism","secondary_identifiers":["MESH:C537869","Orphanet:2654","UMLS:C2931647","MEDGEN:419461","OMIM:272450"],"synonyms":[{"name":"syndesmodysplasic dwarfism","type":"exact"}],"termid":"MONDO:0010093","xrefs":{"Monarch":{"xref_id":"0010093"}}}


id: GO:0031566
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The cellular process in which the contractile ring cytokinetic ring attains its fully functional state.","definition_xrefs":["GOC:vw","PMID:25451933"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular component maintenance","termid":"GO:0043954"},{"relation_name":"is_a","term_name":"actomyosin contractile ring organization","termid":"GO:0044837"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0030036"},{"rel_name":"is_a","termid":"GO:0007010"}],"interesting_parent_ids":["GO:0008150","GO:0007049","GO:0030036","GO:0007010"],"is_obsolete":false,"name":"actomyosin contractile ring maturation","synonyms":[{"name":"actomyosin contractile ring maintenance","type":"related"},{"name":"cytokinesis, contractile ring maintenance","type":"related"}],"termid":"GO:0031566"}


id: PBO:0046852
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fatty acid desaturase 1","termid":"PBO:0046852"}


id: PBO:0057712
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 1298","termid":"PBO:0057712"}


id: GO:0007590
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways involving the fat body. A fat body is a fat-containing cellular structure which serves as an energy reserve. As in, but not restricted to, the true insects (Insecta, ncbi_taxonomy_id:50557).","definition_xrefs":["ISBN:0198506732","GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete fat body metabolic process (sensu Insecta) (obsolete GO:0007590)","synonyms":[{"name":"fat body metabolic process (sensu Insecta)","type":"exact"}],"termid":"GO:0007590"}


id: MONDO:0013721
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any classic complement early component deficiency in which the cause of the disease is a mutation in the C4A gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"classic complement early component deficiency","termid":"MONDO:0000015"},{"relation_name":"is_a","term_name":"immunodeficiency due to a classical component pathway complement deficiency","termid":"MONDO:0015699"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"complement component 4a deficiency","secondary_identifiers":["MESH:C565167","MEDGEN:482272","OMIM:614380","UMLS:C3280642","DOID:0060297","GARD:15798"],"synonyms":[{"name":"C4A classic complement early component deficiency","type":"exact"},{"name":"C4A deficiency","type":"related"},{"name":"C4AD","type":"related"},{"name":"classic complement early component deficiency caused by mutation in C4A","type":"exact"},{"name":"complement component 4A deficiency","type":"related"},{"name":"complement component 4a deficiency","type":"exact"}],"termid":"MONDO:0013721","xrefs":{"Monarch":{"xref_id":"0013721"}}}


id: PBO:0034628
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_nucleosome-dependent_ATPase_activity","termid":"PBO:0034628"}


id: GO:0008235
data:
  {"annotated_genes":["SJAG_03744","SJAG_03586","SJAG_00181","SJAG_03009","SJAG_02033","SJAG_03022","SJAG_01088","SJAG_04858","SJAG_01542","SJAG_00451","SJAG_01896","SJAG_04103","SJAG_00969","SJAG_06636"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[69459,70771],"is_not":false,"summary":null,"term":"GO:0008235"},{"annotations":[64808,60678,74382,65601,76213,99655,57978,116312],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070006"},{"annotations":[58448,76137],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004181"},{"annotations":[61993,61015],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070573"}]},"cv_name":"molecular_function","definition":"Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"metallopeptidase activity","termid":"GO:0008237"},{"relation_name":"is_a","term_name":"exopeptidase activity","termid":"GO:0008238"}],"gene_count":14,"genes_by_uniquename":{"SJAG_00181":null,"SJAG_00451":null,"SJAG_00969":null,"SJAG_01088":null,"SJAG_01542":null,"SJAG_01896":null,"SJAG_02033":null,"SJAG_03009":null,"SJAG_03022":null,"SJAG_03586":null,"SJAG_03744":null,"SJAG_04103":null,"SJAG_04858":null,"SJAG_06636":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0008233"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"}],"interesting_parent_ids":["GO:0140096","GO:0003824","GO:0003674","GO:0008233","GO:0016787"],"is_obsolete":false,"name":"metalloexopeptidase activity","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0008235","terms_by_termid":{"GO:0004181":null,"GO:0008235":null,"GO:0070006":null,"GO:0070573":null}}


id: GO:2001278
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of L-leucine biosynthetic process.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of small molecule metabolic process","termid":"GO:0062013"},{"relation_name":"is_a","term_name":"positive regulation of amino acid biosynthetic process","termid":"GO:2000284"},{"relation_name":"is_a","term_name":"regulation of L-leucine biosynthetic process","termid":"GO:2001276"},{"relation_name":"positively_regulates","term_name":"L-leucine biosynthetic process","termid":"GO:0009098"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0006520"},{"rel_name":"positively_regulates","termid":"GO:0044281"},{"rel_name":"regulates","termid":"GO:0006520"},{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0006520","GO:0044281"],"is_obsolete":false,"name":"positive regulation of L-leucine biosynthetic process","synonyms":[{"name":"positive regulation of L-leucine anabolism","type":"exact"},{"name":"positive regulation of L-leucine biosynthesis","type":"exact"},{"name":"positive regulation of L-leucine formation","type":"exact"},{"name":"positive regulation of L-leucine synthesis","type":"exact"},{"name":"positive regulation of leucine biosynthetic process","type":"broad"}],"termid":"GO:2001278"}


id: PBO:0036198
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_histone_H3-K9_trimethylation_at_centromere_outer_repeat_during_vegetative_growth","termid":"PBO:0036198"}


id: GO:0032655
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of interleukin-12 production.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cytokine production","termid":"GO:0001817"},{"relation_name":"regulates","term_name":"interleukin-12 production","termid":"GO:0032615"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"regulation of interleukin-12 production","secondary_identifiers":["GO:2001182","GO:0045075"],"synonyms":[{"name":"regulation of CLMF production","type":"related"},{"name":"regulation of IL-12 production","type":"exact"},{"name":"regulation of NKSF production","type":"related"},{"name":"regulation of interleukin-12 biosynthetic process","type":"narrow"},{"name":"regulation of interleukin-12 secretion","type":"narrow"}],"termid":"GO:0032655"}


id: GO:0140174
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the activity: a (2R)-2-hydroxycarboxylate + FAD + H+ = a 2-oxocarboxylate + FADH2.","definition_xrefs":["PMID:37863926","RHEA:82511"],"direct_ancestors":[{"relation_name":"is_a","term_name":"(2R)-oxo-acid reductase activity","termid":"GO:0033719"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0016491","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"(2R)-2-hydroxycarboxylate dehydrogenase activity","termid":"GO:0140174"}


id: GO:1905083
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial translational elongation.","definition_xrefs":["PMID:25738458","GO_REF:0000058","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of translational elongation","termid":"GO:0045900"},{"relation_name":"is_a","term_name":"negative regulation of mitochondrial translation","termid":"GO:0070130"},{"relation_name":"is_a","term_name":"regulation of mitochondrial translational elongation","termid":"GO:1905082"},{"relation_name":"negatively_regulates","term_name":"mitochondrial translational elongation","termid":"GO:0070125"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"negatively_regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0140053"}],"interesting_parent_ids":["GO:0010467","GO:0008150","GO:0140053"],"is_obsolete":false,"name":"negative regulation of mitochondrial translational elongation","synonyms":[{"name":"down regulation of mitochondrial translation elongation","type":"exact"},{"name":"down regulation of mitochondrial translational elongation","type":"exact"},{"name":"down-regulation of mitochondrial translation elongation","type":"exact"},{"name":"down-regulation of mitochondrial translational elongation","type":"exact"},{"name":"downregulation of mitochondrial translation elongation","type":"exact"},{"name":"downregulation of mitochondrial translational elongation","type":"exact"},{"name":"inhibition of mitochondrial translation elongation","type":"narrow"},{"name":"inhibition of mitochondrial translational elongation","type":"narrow"},{"name":"negative regulation of mitochondrial translation elongation","type":"exact"}],"termid":"GO:1905083"}


id: PBO:0077323
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein 61","termid":"PBO:0077323"}


id: PBO:0040568
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"beta-1,4-galactosyltransferase 3","termid":"PBO:0040568"}


id: PBO:0087107
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ribosomal protein P1 beta; component of the ribosomal stalk, which is involved in interaction of translational elongation factors with ribosome; free (non-ribosomal) P1 stimulates the phosphorylation of the eIF2 alpha subunit (Sui2p) by Gcn2p; accumulation is regulated by phosphorylation and interaction with the P2 stalk component","termid":"PBO:0087107"}


id: GO:1990559
data:
  {"annotated_genes":["SJAG_03452"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[72234],"is_not":false,"summary":null,"term":"GO:1990559"}]},"cv_name":"biological_process","definition":"The process in which coenzyme A is transported across a mitochondrial membrane, into or out of the mitochondrion.","definition_xrefs":["PMID:11158296"],"direct_ancestors":[{"relation_name":"is_a","term_name":"coenzyme A transmembrane transport","termid":"GO:0035349"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03452":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0055085"}],"interesting_parent_ids":["GO:0055085","GO:0006810","GO:0051179","GO:0008150"],"is_obsolete":false,"name":"mitochondrial coenzyme A transmembrane transport","references_by_uniquename":{"GO_REF:0000033":null},"termid":"GO:1990559","terms_by_termid":{"GO:1990559":null}}


id: PATO:0002092
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A morphology quality inhering in a neoplastic cell by virtue of the bearer's exhibiting breakdown of cell-cell interaction maintaining tissue architecture, proliferative dysregulation and bizarre modification to nucleus size and shape.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"morphology","termid":"PATO:0000051"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"anaplastic","termid":"PATO:0002092"}


id: PBO:0073359
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serpin family E member 3","termid":"PBO:0073359"}


id: PBO:0075569
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"scaffold protein involved in DNA repair","termid":"PBO:0075569"}


id: PBO:0078338
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Glu (CTC) 4-1","termid":"PBO:0078338"}


id: PR:O74388
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- far10 gene.","definition_xrefs":["UniProtKB:O74388","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C3H7.13 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC3H7.13","synonyms":[{"name":"Spom972h-far10","type":"exact"}],"termid":"PR:O74388"}


id: PBO:0001166
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spore wall assembly ADAM family peptidase Mde10","termid":"PBO:0001166"}


id: GO:0033870
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 3'-phosphoadenylyl sulfate + a thiol = adenosine 3',5'-bisphosphate + an S-alkyl thiosulfate.","definition_xrefs":["EC:2.8.2.16"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sulfotransferase activity","termid":"GO:0008146"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016782"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016740","GO:0016782","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"thiol sulfotransferase activity","secondary_identifiers":["RHEA:14637","MetaCyc:THIOL-SULFOTRANSFERASE-RXN"],"synonyms":[{"name":"3'-phosphoadenylyl-sulfate:thiol S-sulfotransferase activity","type":"related"},{"name":"PAPS sulfotransferase activity","type":"broad"},{"name":"adenosine 3'-phosphate 5'-sulphatophosphate sulfotransferase activity","type":"related"}],"termid":"GO:0033870"}


id: PATO:0002040
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A shape quality inhering in a bearer by virtue of the bearer's being convex on both sides or surface.","definition_xrefs":["thefreedictionary:http://www.thefreedictionary.com/biconvexity"],"direct_ancestors":[{"relation_name":"is_a","term_name":"convex","termid":"PATO:0001355"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"biconvex","secondary_identifiers":["Image:http\\://www.thefreedictionary.com/_/viewer.aspx?path=hm&name=A4bicovx"],"termid":"PATO:0002040"}


id: PBO:0040366
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP synthase peripheral stalk-membrane subunit b pseudogene 3","termid":"PBO:0040366"}


id: PBO:0114635
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquinol-cytochrome-c reductase complex subunit 5, Rieske iron-sulfur protein, Rip1","termid":"PBO:0114635"}


id: MONDO:1040037
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any retinopathy caused by autosomal recessive variants in the IMPG1 gene.","definition_xrefs":["PMID:23993198","PMID:28644393"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive disease","termid":"MONDO:0006025"},{"relation_name":"is_a","term_name":"inherited retinal dystrophy","termid":"MONDO:0019118"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0005328","MONDO:0006025"],"is_obsolete":false,"name":"IMPG1-related recessive retinopathy","synonyms":[{"name":"IMPG1-related recessive retinopathy","type":"exact"}],"termid":"MONDO:1040037","xrefs":{"Monarch":{"xref_id":"1040037"}}}


id: FYPO:0002651
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which the attachment of spindle microtubules to the kinetochore during a mitotic or meiotic nuclear division results in the connection of a single kinetochore to both spindle poles.","definition_xrefs":["PMID:17426725","PMID:21306900"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal attachment of spindle microtubules to kinetochore","termid":"FYPO:0000325"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0005447","FYPO:0000002","FYPO:0000631"],"is_obsolete":false,"name":"merotelic kinetochore attachment","synonyms":[{"name":"merotelic attachment of spindle microtubules to kinetochore","type":"exact"}],"termid":"FYPO:0002651"}


id: GO:0030132
data:
  {"annotated_genes":["SJAG_01167","SJAG_00800","SJAG_02805","SJAG_00104"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[80009,58661,110171,76197],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0030122"}]},"cv_name":"cellular_component","definition":"The coat found on coated pits and the coated vesicles derived from coated pits; comprises clathrin and the AP-2 adaptor complex.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"clathrin coat","termid":"GO:0030118"},{"relation_name":"is_a","term_name":"plasma membrane protein complex","termid":"GO:0098797"},{"relation_name":"part_of","term_name":"clathrin-coated pit","termid":"GO:0005905"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00104":null,"SJAG_00800":null,"SJAG_01167":null,"SJAG_02805":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"part_of","termid":"GO:0005886"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005737","GO:0005575","GO:0005886","GO:0032991"],"is_obsolete":false,"name":"clathrin coat of coated pit","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0030132","terms_by_termid":{"GO:0030122":null}}


id: PR:Q9P7J2
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- xlf1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9P7J2"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Xrcc4-like factor 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC24B10.14c","synonyms":[{"name":"Spom972h-xlf1","type":"exact"},{"name":"meiotically up-regulated gene 104 protein (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"non-homologous end-joining protein 1 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9P7J2"}


id: MONDO:1010901
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any neuronal ceroid lipofuscinosis that occurs in cats due to a mutation in the MFSD8 gene.","definition_xrefs":["MONDO:patterns/nonhuman_disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neuronal ceroid lipofuscinosis, domestic cat","termid":"MONDO:1011571"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"neuronal ceroid lipofuscinosis, MFSD8-related, domestic cat","secondary_identifiers":["OMIA:001962-9685"],"synonyms":[{"name":"CLN7","type":"exact"},{"name":"neuronal ceroid lipofuscinosis, 7, domestic cat","type":"related"}],"termid":"MONDO:1010901","xrefs":{"Monarch":{"xref_id":"1010901"}}}


id: PBO:0075964
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"StAR related lipid transfer domain containing 5","termid":"PBO:0075964"}


id: MONDO:0003674
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An electrocardiographic finding of an injury in leads corresponding to the anatomic region of the subendocardial layer of the wall of the heart.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myocardial infarction","termid":"MONDO:0005068"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"subendocardial myocardial infarction","secondary_identifiers":["MEDGEN:75500","UMLS:C0262568","DOID:5849"],"synonyms":[{"name":"myocardial infarction (disease) of subendocardium layer","type":"exact"},{"name":"subendocardium layer myocardial infarction (disease)","type":"exact"}],"termid":"MONDO:0003674","xrefs":{"Monarch":{"xref_id":"0003674"}}}


id: MONDO:0021665
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. A rare autosomal recessive condition caused by mutation(s) in the PHYH gene, encoding phytanoyl-CoA dioxygenase, peroxisomal. It is characterized by abnormalities in the breakdown of phytanic acid and impaired growth of myelin sheaths. Signs and symptoms include neurologic damage, cerebellar degeneration, and neuropathy.","gene_count":0,"genotype_count":0,"name":"obsolete Refsum disease (obsolete MONDO:0021665)","termid":"MONDO:0021665","xrefs":{"Monarch":{"xref_id":"0021665"}}}


id: MONDO:0032803
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"immunodeficiency disease","termid":"MONDO:0021094"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"immunodeficiency 64","secondary_identifiers":["DOID:0111980","MEDGEN:1684716","UMLS:C5231402","GARD:16360","OMIM:618534"],"synonyms":[{"name":"IMD64","type":"related"},{"name":"IMMUNODEFICIENCY 64","type":"related"}],"termid":"MONDO:0032803","xrefs":{"Monarch":{"xref_id":"0032803"}}}


id: PBO:0087618
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of the conserved chromosomal passenger complex (CPC); complex regulates mitotic chromosome segregation; not required for the kinase activity of the complex; mediates the interaction of Sli15p and Bir1p; other complex members are Ipl1p, Sli15p, and Bir1p","termid":"PBO:0087618"}


id: MONDO:0008687
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Woronets trait","secondary_identifiers":["MEDGEN:348570","OMIM:194320","UMLS:C1860237"],"synonyms":[{"name":"Woronets trait","type":"exact"}],"termid":"MONDO:0008687","xrefs":{"Monarch":{"xref_id":"0008687"}}}


id: MONDO:0001268
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A loss of gum tissue resulting in an exposure of the roots of the teeth.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gingival disorder","termid":"MONDO:0002021"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"gingival recession","secondary_identifiers":["ICD9:523.21","UMLS:C0017572","ICD9:523.2","icd11.foundation:1059404242","DOID:1134","ICD9:523.24","ICD9:523.22","MESH:D005889","SCTID:59898000","ICD10CM:K06.0","MEDGEN:6607","ICD9:523.20","ICD9:523.23"],"synonyms":[{"name":"gingival recession","type":"exact"},{"name":"gingival recession, localised","type":"exact"},{"name":"gingival recession, localized","type":"exact"},{"name":"gingival recession, unspecified","type":"exact"},{"name":"localised gingival recession","type":"exact"},{"name":"localized gingival recession","type":"exact"},{"name":"minimal gingival recession","type":"exact"},{"name":"moderate gingival recession","type":"exact"},{"name":"severe gingival recession","type":"exact"}],"termid":"MONDO:0001268","xrefs":{"Monarch":{"xref_id":"0001268"}}}


id: PBO:0062164
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 4 subfamily K member 5","termid":"PBO:0062164"}


id: PBO:0079306
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"testis-specific transcript, Y-linked 3","termid":"PBO:0079306"}


id: MONDO:0100232
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An inherited susceptibility or predisposition to developing psoriatic arthritis.","definition_xrefs":["MONDO:patterns/inherited_susceptibility"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inherited disease susceptibility","termid":"MONDO:0020573"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"psoriatic arthritis, susceptibility to","secondary_identifiers":["MEDGEN:322604","OMIM:607507","UMLS:C1835223"],"synonyms":[{"name":"psoriatic arthritis, susceptibility","type":"exact"},{"name":"psoriatic arthritis, susceptibility to","type":"exact"}],"termid":"MONDO:0100232","xrefs":{"Monarch":{"xref_id":"0100232"}}}


id: MONDO:0013250
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An autosomal recessive nonsyndromic deafness that has material basis in variation in the chromosome region 17p12-q11.2.","definition_xrefs":["DOID:0110531","PMID:19888295"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hearing loss, autosomal recessive","termid":"MONDO:0019588"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0019497"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0019497"],"is_obsolete":false,"name":"autosomal recessive nonsyndromic hearing loss 85","secondary_identifiers":["MEDGEN:463629","OMIM:613392","UMLS:C3160740","GARD:22635"],"synonyms":[{"name":"DFNB85","type":"narrow"},{"name":"autosomal recessive deafness 85","type":"narrow"},{"name":"autosomal recessive nonsyndromic deafness 85","type":"narrow"},{"name":"autosomal recessive nonsyndromic deafness type 85","type":"narrow"},{"name":"deafness, autosomal recessive 85","type":"narrow"}],"termid":"MONDO:0013250","xrefs":{"Monarch":{"xref_id":"0013250"}}}


id: GO:0019800
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The formation of a cross-link between peptide chains mediated by a chondroitin 4-sulfate glycosaminoglycan that originates from a typical O-glycosidic link to serine of one chain; the other chain is esterified, via the alpha-carbon of its C-terminal Asp, to C-6 of an internal N-acetylgalactosamine of the glycosaminoglycan chain.","definition_xrefs":["RESID:AA0219","PMID:1898736"],"gene_count":0,"genotype_count":0,"name":"obsolete peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (obsolete GO:0019800)","synonyms":[{"name":"peptide cross-linking via chondroitin 4-sulphate glycosaminoglycan","type":"exact"}],"termid":"GO:0019800"}


id: MONDO:0014811
data:
  {"annotated_genes":["SJAG_02437"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87596],"is_not":false,"summary":null,"term":"MONDO:0014811"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Mendelian neurodevelopmental disorder","termid":"MONDO:0100500"},{"relation_name":"is_a","term_name":"complex neurodevelopmental disorder with motor features","termid":"MONDO:0100516"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02437":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0700092"}],"interesting_parent_ids":["MONDO:0700092"],"is_obsolete":false,"name":"cerebellar atrophy, visual impairment, and psychomotor retardation;","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:616875","MEDGEN:905041","UMLS:C4225172","DOID:0081276"],"synonyms":[{"name":"CAVIPMR","type":"related"},{"name":"cerebellar atrophy, visual impairment, and psychomotor retardation","type":"related"}],"termid":"MONDO:0014811","terms_by_termid":{"MONDO:0014811":null},"xrefs":{"Monarch":{"xref_id":"0014811"}}}


id: GO:0004168
data:
  {"annotated_genes":["SJAG_04231"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[82079],"is_not":false,"summary":null,"term":"GO:0004168"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: CTP + dolichol = CDP + dolichyl phosphate.","definition_xrefs":["EC:2.7.1.108"],"direct_ancestors":[{"relation_name":"is_a","term_name":"kinase activity","termid":"GO:0016301"},{"relation_name":"is_a","term_name":"phosphotransferase activity, alcohol group as acceptor","termid":"GO:0016773"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04231":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016301"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0016301","GO:0003824","GO:0016740"],"is_obsolete":false,"name":"dolichol kinase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["Reactome:R-HSA-446195","RHEA:13133","MetaCyc:DOLICHOL-KINASE-RXN","Reactome:R-HSA-4755600"],"synonyms":[{"name":"CTP:dolichol O-phosphotransferase activity","type":"related"},{"name":"dolichol phosphokinase activity","type":"related"}],"termid":"GO:0004168","terms_by_termid":{"GO:0004168":null}}


id: MONDO:0018207
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"2p13.2 microdeletion syndrome is a rare partial autosomal monosomy characterized by global development delay, intellectual disability, behavioral abnormalities (hyperactivity, attention deficit and autistic behaviors), brachycephaly and variable facial dysmorphism. Other associated features may include vertebral fusions, mild contractures of knees and elbows, and feeding difficulties during infancy.","definition_xrefs":["Orphanet:363680"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"},{"relation_name":"is_a","term_name":"partial deletion of the short arm of chromosome 2","termid":"MONDO:0016884"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2p13.2 microdeletion syndrome","secondary_identifiers":["GARD:21557","MEDGEN:1662313","UMLS:C4749460"],"synonyms":[{"name":"Del(2)(p13.2)","type":"exact"}],"termid":"MONDO:0018207","xrefs":{"Monarch":{"xref_id":"0018207"}}}


id: MONDO:0001027
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A gonorrhea that involves the seminal vesicle.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gonorrhea","termid":"MONDO:0004277"},{"relation_name":"is_a","term_name":"vesiculitis","termid":"MONDO:0004767"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"gonococcal seminal vesiculitis","secondary_identifiers":["DOID:10400","MEDGEN:662073","icd11.foundation:1226540022","SCTID:301990003","UMLS:C0578661"],"synonyms":[{"name":"gonococcal seminal vesiculitis (acute)","type":"exact"},{"name":"gonorrhea of seminal vesicle","type":"exact"},{"name":"gonorrhoea of seminal vesicle","type":"exact"},{"name":"seminal vesicle gonorrhea","type":"exact"},{"name":"seminal vesicle gonorrhoea","type":"exact"}],"termid":"MONDO:0001027","xrefs":{"Monarch":{"xref_id":"0001027"}}}


id: MONDO:0000879
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Candidiasis of the skin manifested as eczema-like lesions of the interdigital spaces, perleche, or chronic paronychia. (Dorland, 27th ed)","definition_xrefs":["MESH:D002179"],"direct_ancestors":[{"relation_name":"is_a","term_name":"candidiasis","termid":"MONDO:0002026"},{"relation_name":"is_a","term_name":"tinea infection","termid":"MONDO:0005982"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"cutaneous candidiasis","secondary_identifiers":["DOID:0080161","MEDGEN:2427","UMLS:C0006846"],"synonyms":[{"name":"zone of skin candidiasis","type":"exact"}],"termid":"MONDO:0000879","xrefs":{"Monarch":{"xref_id":"0000879"}}}


id: GO:0061278
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric nephron tubule morphogenesis.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epithelial cell migration involved in nephron tubule morphogenesis","termid":"GO:0072155"},{"relation_name":"part_of","term_name":"mesonephric nephron tubule morphogenesis","termid":"GO:0061240"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"epithelial cell migration involved in mesonephric nephron tubule morphogenesis","termid":"GO:0061278"}


id: PBO:0079172
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"testis specific protein Y-linked 1","termid":"PBO:0079172"}


id: PBO:0061658
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NUMB endocytic adaptor protein","termid":"PBO:0061658"}


id: MONDO:0600005
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An allergic disease involving venom.","definition_xrefs":["PMID:26154789"],"direct_ancestors":[{"relation_name":"is_a","term_name":"allergic disease","termid":"MONDO:0005271"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"venom allergy","secondary_identifiers":["MEDGEN:1387536","UMLS:C4510560"],"synonyms":[{"name":"IgE-mediated venom hypersensitivity","type":"exact"},{"name":"venom hypersensitivity","type":"exact"}],"termid":"MONDO:0600005","xrefs":{"Monarch":{"xref_id":"0600005"}}}


id: MONDO:0000761
data:
  {"annotated_genes":["SJAG_02035","SJAG_02317","SJAG_01806","SJAG_00112","SJAG_03424","SJAG_00786","SJAG_03286","SJAG_03635","SJAG_02846","SJAG_01804","SJAG_01548","SJAG_03244","SJAG_00441","SJAG_04663","SJAG_04324","SJAG_01465"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87945,87946,87944],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013256"},{"annotations":[87504,87503],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007925"},{"annotations":[88058],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010334"},{"annotations":[87767,87769,87771,87772,87770,87766,87768],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010767"},{"annotations":[87411],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014848"},{"annotations":[88944],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008644"},{"annotations":[87388],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008684"}]},"cv_name":"mondo","definition":"A chromosomal disorder consisting of the absence of a part of a chromosome.","direct_ancestors":[{"relation_name":"is_a","term_name":"chromosomal disorder","termid":"MONDO:0019040"}],"gene_count":16,"genes_by_uniquename":{"SJAG_00112":null,"SJAG_00441":null,"SJAG_00786":null,"SJAG_01465":null,"SJAG_01548":null,"SJAG_01804":null,"SJAG_01806":null,"SJAG_02035":null,"SJAG_02317":null,"SJAG_02846":null,"SJAG_03244":null,"SJAG_03286":null,"SJAG_03424":null,"SJAG_03635":null,"SJAG_04324":null,"SJAG_04663":null},"genotype_count":0,"is_obsolete":false,"name":"syndrome caused by partial chromosomal deletion","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["DOID:0060388"],"synonyms":[{"name":"chromosomal deletion syndrome","type":"related"},{"name":"microdeletion syndrome","type":"exact"}],"termid":"MONDO:0000761","terms_by_termid":{"MONDO:0007925":null,"MONDO:0008644":null,"MONDO:0008684":null,"MONDO:0010334":null,"MONDO:0010767":null,"MONDO:0013256":null,"MONDO:0014848":null},"xrefs":{"Monarch":{"xref_id":"0000761"}}}


id: PBO:0078894
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Gln (anticodon CTG) 5-1","termid":"PBO:0078894"}


id: GO:0006278
data:
  {"annotated_genes":["SJAG_01378","SJAG_01677","SJAG_02194","SJAG_03685","SJAG_05979","SJAG_04586","SJAG_04266","SJAG_00939","SJAG_03855"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[78795],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0032210"},{"annotations":[81970,117806,71378,115683,109956,72412,82033,92450],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0007004"}]},"cv_name":"biological_process","definition":"A DNA biosynthetic process that uses RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strand.","definition_xrefs":["GOC:mah","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA biosynthetic process","termid":"GO:0071897"}],"gene_count":9,"genes_by_uniquename":{"SJAG_00939":null,"SJAG_01378":null,"SJAG_01677":null,"SJAG_02194":null,"SJAG_03685":null,"SJAG_03855":null,"SJAG_04266":null,"SJAG_04586":null,"SJAG_05979":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006259"}],"interesting_parent_ids":["GO:0006259","GO:0008150"],"is_obsolete":false,"name":"RNA-templated DNA biosynthetic process","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-162589"],"synonyms":[{"name":"RNA-dependent DNA biosynthetic process","type":"exact"}],"termid":"GO:0006278","terms_by_termid":{"GO:0007004":null,"GO:0032210":null}}


id: GO:1904901
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of myosin II filament organization.","definition_xrefs":["GO_REF:0000058","GOC:TermGenie","PMID:22761445"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of myosin II filament organization","termid":"GO:0043519"},{"relation_name":"is_a","term_name":"positive regulation of cytoskeleton organization","termid":"GO:0051495"},{"relation_name":"is_a","term_name":"positive regulation of supramolecular fiber organization","termid":"GO:1902905"},{"relation_name":"positively_regulates","term_name":"myosin II filament organization","termid":"GO:0031038"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0007010"},{"rel_name":"regulates","termid":"GO:0007010"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0030036"},{"rel_name":"regulates","termid":"GO:0030036"}],"interesting_parent_ids":["GO:0007010","GO:0008150","GO:0030036"],"is_obsolete":false,"name":"positive regulation of myosin II filament organization","synonyms":[{"name":"activation of myosin II filament assembly or disassembly","type":"related"},{"name":"activation of myosin II filament organisation","type":"narrow"},{"name":"activation of myosin II filament organization","type":"narrow"},{"name":"activation of myosin II polymerization or depolymerization","type":"related"},{"name":"positive regulation of myosin II filament assembly or disassembly","type":"related"},{"name":"positive regulation of myosin II filament organisation","type":"exact"},{"name":"positive regulation of myosin II polymerization or depolymerization","type":"related"},{"name":"up regulation of myosin II filament assembly or disassembly","type":"related"},{"name":"up regulation of myosin II filament organisation","type":"exact"},{"name":"up regulation of myosin II filament organization","type":"exact"},{"name":"up regulation of myosin II polymerization or depolymerization","type":"related"},{"name":"up-regulation of myosin II filament assembly or disassembly","type":"related"},{"name":"up-regulation of myosin II filament organisation","type":"exact"},{"name":"up-regulation of myosin II filament organization","type":"exact"},{"name":"up-regulation of myosin II polymerization or depolymerization","type":"related"},{"name":"upregulation of myosin II filament assembly or disassembly","type":"related"},{"name":"upregulation of myosin II filament organisation","type":"exact"},{"name":"upregulation of myosin II filament organization","type":"exact"},{"name":"upregulation of myosin II polymerization or depolymerization","type":"related"}],"termid":"GO:1904901"}


id: GO:0051992
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine = di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP.","definition_xrefs":["RHEA:28386"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphotransferase activity, for other substituted phosphate groups","termid":"GO:0016780"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016780"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016740","GO:0016780"],"is_obsolete":false,"name":"UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity","secondary_identifiers":["MetaCyc:PHOSNACMURPENTATRANS-RXN"],"termid":"GO:0051992"}


id: PBO:0015247
data:
  {"annotation_feature_type":"gene","cv_name":"subunit_composition","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"homomeric(5)","termid":"PBO:0015247"}


id: PBO:0047082
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 136 member A","termid":"PBO:0047082"}


id: MONDO:0016058
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"combined dystonia","termid":"MONDO:0020065"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0003441"}],"interesting_parent_ids":["MONDO:0003441"],"is_obsolete":false,"name":"paroxysmal dystonia","secondary_identifiers":["SCTID:230310003","UMLS:C0393588","Orphanet:200037","icd11.foundation:2047715743","ICD9:333.99","GARD:20340","MEDGEN:97951"],"termid":"MONDO:0016058","xrefs":{"Monarch":{"xref_id":"0016058"}}}


id: MONDO:0004900
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"vestibular disorder","termid":"MONDO:0002643"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peripheral vertigo","secondary_identifiers":["SCTID:50438001","ICD9:386.1","MEDGEN:102334","ICD9:386.19","DOID:9847","UMLS:C0155501","ICD9:386.10"],"termid":"MONDO:0004900","xrefs":{"Monarch":{"xref_id":"0004900"}}}


id: PBO:0029317
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_histone_H2A_phosphorylation_at_subtelomere","termid":"PBO:0029317"}


id: MONDO:0019780
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A congenital malformation of the external ear and the most extreme form of microtia characterized by the complete absence of the external ear and auditory canal, conductive hearing loss, attention deficit disorders and delayed language development.","definition_xrefs":["Orphanet:93976"],"direct_ancestors":[{"relation_name":"is_a","term_name":"developmental defect during embryogenesis","termid":"MONDO:0019755"},{"relation_name":"is_a","term_name":"otorhinolaryngologic disease","termid":"MONDO:0024623"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"anotia","secondary_identifiers":["MedDRA:10002654","icd11.foundation:2056675356","GARD:16835","ICD9:744.01","SCTID:57436000","UMLS:C0702139","MEDGEN:152377"],"termid":"MONDO:0019780","xrefs":{"Monarch":{"xref_id":"0019780"}}}


id: PBO:0000724
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/threonine protein kinase Orb6","termid":"PBO:0000724"}


id: GO:0106435
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: a carboxylic ester + H2O = a carboxylate + an alcohol + H+.","definition_xrefs":["RHEA:21164"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxylic ester hydrolase activity","termid":"GO:0052689"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016788"}],"interesting_parent_ids":["GO:0016787","GO:0003824","GO:0003674","GO:0016788"],"is_obsolete":false,"name":"carboxylesterase activity","secondary_identifiers":["MetaCyc:CARBOXYLESTERASE-RXN","Reactome:R-HSA-9619024","EC:3.1.1.1","Reactome:R-HSA-9727567","Reactome:R-HSA-9749647"],"synonyms":[{"name":"B-esterase activity","type":"narrow"},{"name":"ali-esterase activity","type":"related"},{"name":"alpha-carboxylesterase activity","type":"narrow"},{"name":"cocaine esterase","type":"narrow"},{"name":"nonspecific carboxylesterase activity","type":"related"},{"name":"procaine esterase","type":"narrow"},{"name":"serine esterase activity","type":"narrow"},{"name":"triacetin esterase","type":"narrow"},{"name":"vitamin A esterase","type":"narrow"}],"termid":"GO:0106435"}


id: PBO:0027504
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_growth_on_fluconazole","termid":"PBO:0027504"}


id: _global:related_via_localization_to
data:
  {"annotation_feature_type":"gene","cv_name":"external","definition":"A relationship that holds via some process of localization","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"related_via_localization_to","secondary_identifiers":["RO:0002337"],"termid":"_global:related_via_localization_to"}


id: GO:0097506
data:
  {"annotated_genes":["SJAG_02528"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[80036],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004844"}]},"cv_name":"molecular_function","definition":"DNA N-glycosylase activity acting on deaminated bases.","definition_xrefs":["GOC:al","PMID:18789404"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA N-glycosylase activity","termid":"GO:0019104"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02528":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0016798"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0140097"}],"interesting_parent_ids":["GO:0003674","GO:0016787","GO:0016798","GO:0003824","GO:0140097"],"is_obsolete":false,"name":"deaminated base DNA N-glycosylase activity","references_by_uniquename":{"GO_REF:0000033":null},"synonyms":[{"name":"DNA glycosylase activity acting on deaminated bases","type":"exact"},{"name":"deaminated base DNA glycosylase activity","type":"exact"}],"termid":"GO:0097506","terms_by_termid":{"GO:0004844":null}}


id: _global:results_in_transport_to_from_or_in
data:
  {"annotation_feature_type":"gene","cv_name":"external","direct_ancestors":[{"relation_name":"is_a","term_name":"related_via_localization_to","termid":"_global:related_via_localization_to"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"results_in_transport_to_from_or_in","secondary_identifiers":["RO:0002344"],"termid":"_global:results_in_transport_to_from_or_in"}


id: MONDO:0022423
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete alpha-2 deficient collagen disease (obsolete MONDO:0022423)","termid":"MONDO:0022423","xrefs":{"Monarch":{"xref_id":"0022423"}}}


id: PBO:0028099
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-altered_DNA_binding_specificity","termid":"PBO:0028099"}


id: MONDO:0016942
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"partial trisomy/tetrasomy of chromosome 5","termid":"MONDO:0016925"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"partial trisomy/tetrasomy of the short arm of chromosome 5","secondary_identifiers":["GARD:20862","UMLS:C5679722","Orphanet:262725","MEDGEN:1826044"],"synonyms":[{"name":"partial duplication/triplication of chromosome 5p","type":"exact"},{"name":"partial duplication/triplication of the short arm of chromosome 5","type":"exact"},{"name":"partial trisomy/tetrasomy of chromosome 5p","type":"exact"},{"name":"partial trisomy/tetrasomy of the short arm of chromosome type 5","type":"exact"}],"termid":"MONDO:0016942","xrefs":{"Monarch":{"xref_id":"0016942"}}}


id: PBO:0027380
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-nuclear_pore_aggregation_in_cytoplasm","termid":"PBO:0027380"}


id: GO:2000182
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of progesterone biosynthetic process.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of ketone biosynthetic process","termid":"GO:0010566"},{"relation_name":"is_a","term_name":"regulation of hormone biosynthetic process","termid":"GO:0046885"},{"relation_name":"is_a","term_name":"regulation of steroid biosynthetic process","termid":"GO:0050810"},{"relation_name":"regulates","term_name":"progesterone biosynthetic process","termid":"GO:0006701"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006629"},{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006629","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"regulation of progesterone biosynthetic process","synonyms":[{"name":"regulation of progesterone anabolism","type":"exact"},{"name":"regulation of progesterone biosynthesis","type":"exact"},{"name":"regulation of progesterone formation","type":"exact"},{"name":"regulation of progesterone synthesis","type":"exact"}],"termid":"GO:2000182"}


id: PBO:0042870
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cilia and flagella associated protein 100","termid":"PBO:0042870"}


id: MONDO:0008953
data:
  {"annotated_genes":["SJAG_02619"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88642],"is_not":false,"summary":null,"term":"MONDO:0008953"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"peroxisome biogenesis disorder","termid":"MONDO:0019234"},{"relation_name":"is_a","term_name":"peroxisome biogenesis disorder due to PEX1 defect","termid":"MONDO:0100259"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02619":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005244"},{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0019053"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0005244","MONDO:0005559","MONDO:0019053","MONDO:0005066"],"is_obsolete":false,"name":"peroxisome biogenesis disorder 1A (Zellweger)","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C4721541","OMIM:214100","DOID:0080476","MEDGEN:1648474"],"synonyms":[{"name":"Cerebrohepatorenal syndrome","type":"related"},{"name":"PBD1A","type":"related"},{"name":"Zs","type":"related"},{"name":"peroxisome biogenesis disorder 1A (Zellweger)","type":"exact"},{"name":"peroxisome biogenesis disorder, complementation group 1","type":"related"},{"name":"peroxisome biogenesis disorder, complementation group E","type":"related"}],"termid":"MONDO:0008953","terms_by_termid":{"MONDO:0008953":null},"xrefs":{"Monarch":{"xref_id":"0008953"}}}


id: PBO:0012280
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SIP/FAR complex FHA domain subunit Far10/Csc1","termid":"PBO:0012280"}


id: PBO:0046241
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"elongin C pseudogene 35","termid":"PBO:0046241"}


id: PBO:0064043
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"piwi-interacting RNA cluster 77","termid":"PBO:0064043"}


id: PBO:0111681
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PARG pseudogene 1","termid":"PBO:0111681"}


id: GO:0031819
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a P2Y10 nucleotide receptor.","definition_xrefs":["GOC:mah","GOC:nln"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G protein-coupled nucleotide receptor binding","termid":"GO:0031811"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0005488","GO:0005515","GO:0003674"],"is_obsolete":false,"name":"P2Y10 nucleotide receptor binding","synonyms":[{"name":"P2Y10 nucleotide receptor ligand","type":"narrow"}],"termid":"GO:0031819"}


id: PBO:0074246
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 66 member 2","termid":"PBO:0074246"}


id: GO:0099610
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The initiating cycle of an action potential. In vertebrate neurons this typically occurs at an axon hillock. Not all initiated axon potentials propagate.","definition_xrefs":["ISBN:978-0071390118","PMID:19439602"],"direct_ancestors":[{"relation_name":"is_a","term_name":"action potential","termid":"GO:0001508"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"action potential initiation","synonyms":[{"name":"action potential firing","type":"exact"},{"name":"action potential triggering","type":"exact"}],"termid":"GO:0099610"}


id: GO:0006170
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate).","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"purine deoxyribonucleotide biosynthetic process","termid":"GO:0009153"},{"relation_name":"is_a","term_name":"purine deoxyribonucleoside monophosphate biosynthetic process","termid":"GO:0009171"},{"relation_name":"is_a","term_name":"dAMP metabolic process","termid":"GO:0046053"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0055086","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"dAMP biosynthetic process","synonyms":[{"name":"dAMP anabolism","type":"exact"},{"name":"dAMP biosynthesis","type":"exact"},{"name":"dAMP formation","type":"exact"},{"name":"dAMP synthesis","type":"exact"}],"termid":"GO:0006170"}


id: PBO:0077665
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TNF receptor superfamily member 11b","termid":"PBO:0077665"}


id: FYPO:0002755
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of cysteine synthase activity is decreased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased catalytic activity","termid":"FYPO:0000663"},{"relation_name":"is_a","term_name":"abnormal cysteine synthase activity","termid":"FYPO:0002754"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000661","FYPO:0000654","FYPO:0000002","FYPO:0001985","FYPO:0005447","FYPO:0000652","FYPO:0000707"],"is_obsolete":false,"name":"decreased cysteine synthase activity","synonyms":[{"name":"reduced cysteine synthase activity","type":"exact"}],"termid":"FYPO:0002755"}


id: FYPO:0007112
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process in which depolymerization (i.e. removal of tubulin dimers) of microtubules occurs at a lower rate, or speed, as part of centromere clustering during meiotic prophase I.","definition_xrefs":["PMID:23770679","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal microtubule depolymerization","termid":"FYPO:0007111"},{"relation_name":"is_a","term_name":"decreased microtubule depolymerisation involved in meitotic centromere clustering during meiotic prophase I","termid":"FYPO:0009058"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000054"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000054","FYPO:0005447","FYPO:0001985"],"is_obsolete":false,"name":"decreased rate of microtubule depolymerization involved in meiotic centromere clustering during meiotic prophase I","synonyms":[{"name":"decreased microtubule depolymerisation speed involved in meiotic centromere clustering during meiotic prophase I","type":"exact"},{"name":"decreased microtubule depolymerization speed involved in meiotic centromere clustering during meiotic prophase I","type":"exact"},{"name":"decreased microtubule shrinkage shrinkage speed involved in meiotic centromere clustering during meiotic prophase I","type":"exact"},{"name":"decreased microtubule shrinkage speed involved in meiotic centromere clustering during meiotic prophase I","type":"exact"},{"name":"decreased rate of microtubule depolymerisation involved in meiotic centromere clustering during meiotic prophase I","type":"exact"},{"name":"decreased rate of microtubule depolymerization involved in meiotic centromere clustering during prophase I","type":"exact"},{"name":"decreased rate of microtubule depolymerization involved in meiotic chromosome clustering during meiotic prophase I","type":"related"},{"name":"decreased rate of microtubule depolymerization involved in meiotic kinetochore retrieval during meiotic prophase I","type":"related"},{"name":"reduced rate of microtubule depolymerization involved in meiotic centromere clustering during meiotic prophase I","type":"exact"}],"termid":"FYPO:0007112"}


id: PBO:0043257
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"claudin 15","termid":"PBO:0043257"}


id: PBO:0087745
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of the SWI/SNF chromatin remodeling complex; SWI/SNF regulates transcription by remodeling chromosomes; contains SANT domain that is required for SWI/SNF assembly; is essential for displacement of histone H2A-H2B dimers during ATP-dependent remodeling; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2; relocates to the cytosol under hypoxic conditions","termid":"PBO:0087745"}


id: MONDO:0015879
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete non-syndromic diaphragmatic or thoracic malformation (obsolete MONDO:0015879)","secondary_identifiers":["Orphanet:180776"],"synonyms":[{"name":"isolated diaphragmatic or thoracic malformation","type":"related"},{"name":"nonsyndromic diaphragmatic or thoracic malformation","type":"exact"}],"termid":"MONDO:0015879","xrefs":{"Monarch":{"xref_id":"0015879"}}}


id: GO:0140795
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: H2O + histone H3 L-arginyl (position 2)= histone H3 L-citrullyl (position 2) + NH4+, resulting in histone H3 citrullination at position 2.","definition_xrefs":["PMID:15339660"],"direct_ancestors":[{"relation_name":"is_a","term_name":"histone H3 arginine deiminase activity","termid":"GO:0141057"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016810"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0140096","GO:0016787","GO:0003824","GO:0016810"],"is_obsolete":false,"name":"histone H3R2 arginine deiminase activity","synonyms":[{"name":"H3-R2 citrullination","type":"exact"},{"name":"histone H3-R2 arginine deiminase activity","type":"exact"},{"name":"histone-arginine deiminase activity (H3-R2 specific)","type":"exact"}],"termid":"GO:0140795"}


id: GO:1905307
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a miconazole stimulus.","definition_xrefs":["GO_REF:0000071","PMID:26108447","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to nitrogen compound","termid":"GO:1901698"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to miconazole","termid":"GO:1905307"}


id: GO:0061189
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.","definition_xrefs":["GOC:BHF","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of developmental process","termid":"GO:0051094"},{"relation_name":"is_a","term_name":"regulation of sclerotome development","termid":"GO:0061190"},{"relation_name":"positively_regulates","term_name":"sclerotome development","termid":"GO:0061056"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of sclerotome development","termid":"GO:0061189"}


id: GO:0009631
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases freezing tolerance of an organism in response to low, nonfreezing temperatures.","definition_xrefs":["GOC:syr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to cold","termid":"GO:0009409"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cold acclimation","termid":"GO:0009631"}


id: PBO:0060261
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myeloma overexpressed","termid":"PBO:0060261"}


id: PBO:0040030
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"armadillo repeat containing X-linked 5","termid":"PBO:0040030"}


id: GO:0018238
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The modification of peptidyl-lysine to form peptidyl-N6-1-carboxyethyl-L-lysine.","definition_xrefs":["RESID:AA0115"],"gene_count":0,"genotype_count":0,"name":"obsolete peptidyl-lysine carboxyethylation (obsolete GO:0018238)","synonyms":[{"name":"protein amino acid carboxyethylation","type":"exact"}],"termid":"GO:0018238"}


id: GO:0033228
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of cysteine from inside of a cell, across the plasma membrane and into the extracellular region.","definition_xrefs":["GOC:mlg"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amino acid export across plasma membrane","termid":"GO:0032973"},{"relation_name":"is_a","term_name":"cysteine transmembrane transport","termid":"GO:1903712"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0055085"}],"interesting_parent_ids":["GO:0051179","GO:0055085","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"cysteine export across plasma membrane","synonyms":[{"name":"cysteine export","type":"broad"}],"termid":"GO:0033228"}


id: FYPO:0004817
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of small RNA (such as siRNA) derived from antisense transcription of ribosomal DNA measured in a cell is lower than normal.","definition_xrefs":["PomBase:mah","PMID:25417108"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased antisense RNA level","termid":"FYPO:0004816"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0006551"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001320","FYPO:0006551","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"decreased rDNA antisense small RNA level","synonyms":[{"name":"decreased accumulation of rDNA antisense small RNAs","type":"related"},{"name":"decreased antisense small RNA at rDNA","type":"exact"},{"name":"decreased antisense transcription-derived small RNA level at rDNA","type":"exact"},{"name":"decreased rDNA antisense small RNA accumulation","type":"related"},{"name":"decreased rDNA antisense small RNA level during mitotic cell cycle","type":"related"},{"name":"decreased rDNA antisense small RNA level during vegetative growth","type":"exact"},{"name":"reduced rDNA antisense small RNA level","type":"exact"}],"termid":"FYPO:0004817"}


id: GO:1900576
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving gerfelin.","definition_xrefs":["GOC:di","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"catechol-containing compound metabolic process","termid":"GO:0009712"},{"relation_name":"is_a","term_name":"ether metabolic process","termid":"GO:0018904"},{"relation_name":"is_a","term_name":"secondary metabolic process","termid":"GO:0019748"},{"relation_name":"is_a","term_name":"carboxylic acid metabolic process","termid":"GO:0019752"},{"relation_name":"is_a","term_name":"benzene-containing compound metabolic process","termid":"GO:0042537"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0019748"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0044281","GO:0019748"],"is_obsolete":false,"name":"gerfelin metabolic process","synonyms":[{"name":"gerfelin metabolism","type":"exact"}],"termid":"GO:1900576"}


id: GO:0032597
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of a B cell receptor into a membrane raft.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"B cell receptor transport within lipid bilayer","termid":"GO:0032595"},{"relation_name":"is_a","term_name":"protein transport into membrane raft","termid":"GO:0032596"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0061024"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0051179","GO:0061024","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"B cell receptor transport into membrane raft","synonyms":[{"name":"B cell receptor translocation into membrane raft","type":"exact"},{"name":"B cell receptor transport into lipid raft","type":"exact"},{"name":"BCR translocation into membrane raft","type":"exact"},{"name":"BCR transport into membrane raft","type":"exact"}],"termid":"GO:0032597"}


id: PBO:0038898
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ADGRA3 pseudogene 1","termid":"PBO:0038898"}


id: MONDO:0035614
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare sporadic human prion disease characterized by adult onset of progredient neurodegeneration presenting as a combination of psychiatric, sleep, and oculomotor disturbances, with development of progressive cognitive impairment (the predominantly affected cognitive domains being memory, temporal and/or spatial orientation, language, executive functions, and attention), postural instability, and sometimes additional motor abnormalities and autonomic hyperactivity, in the course of the disease. Bilateral thalamic hypometabolism on FDG-PET imaging and positive prion seeding activity in the cerebrospinal fluid are present in many cases. The disease is fatal within typically two to three years.","definition_xrefs":["Orphanet:586130"],"direct_ancestors":[{"relation_name":"is_a","term_name":"prion disease","termid":"MONDO:0005429"},{"relation_name":"is_a","term_name":"human prion disease","termid":"MONDO:0018926"},{"relation_name":"is_a","term_name":"inherited neurodegenerative disorder","termid":"MONDO:0024237"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"sporadic fatal insomnia","secondary_identifiers":["ICD10CM:A81.9","MEDGEN:1799312","GARD:22349","UMLS:C5567889"],"termid":"MONDO:0035614","xrefs":{"Monarch":{"xref_id":"0035614"}}}


id: PBO:0073972
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 22 member 23","termid":"PBO:0073972"}


id: PBO:0049612
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"H3 histone pseudogene 15","termid":"PBO:0049612"}


id: GO:0007542
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The transmission of information about sexual status, from the initial general determination, to signals specific to the germ-line.","definition_xrefs":["GOC:ems"],"direct_ancestors":[{"relation_name":"is_a","term_name":"primary sex determination","termid":"GO:0007538"},{"relation_name":"part_of","term_name":"germ-line sex determination","termid":"GO:0018992"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"primary sex determination, germ-line","termid":"GO:0007542"}


id: GO:0060225
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cell fate commitment","termid":"GO:0010455"},{"relation_name":"is_a","term_name":"positive regulation of photoreceptor cell differentiation","termid":"GO:0046534"},{"relation_name":"is_a","term_name":"regulation of retinal rod cell fate commitment","termid":"GO:0060224"},{"relation_name":"positively_regulates","term_name":"retinal rod cell fate commitment","termid":"GO:0060223"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of retinal rod cell fate commitment","termid":"GO:0060225"}


id: MONDO:0015414
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Paramedian nasal cleft is a rare developmental defect during embryogenesis characterized by a unilateral or bilateral coloboma of the nose, ranging in severity from a small notch, resulting in minor deviation of the nasal septum, to variable-sized clefts of the nasal ala which may be associated with small cysts or sinuses in the nasal midline. Defect may be isolated or may occur in association with cleft lip and/or other craniofacial anomalies (e.g. hypertelorism, broadening of nasal root, midline cleft). Dorsum and apex of nose are usually well preserved.","definition_xrefs":["Orphanet:141242"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bifid nose, autosomal recessive","termid":"MONDO:0008866"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0006025"],"is_obsolete":false,"name":"paramedian nasal cleft","secondary_identifiers":["SCTID:204521002","icd11.foundation:1147502981","UMLS:C4759655","GARD:16973","ICD9:748.1","MEDGEN:1681273"],"synonyms":[{"name":"Tessier number 1 cleft","type":"exact"},{"name":"alar cleft","type":"exact"},{"name":"alar rim cleft","type":"exact"},{"name":"cleft nose","type":"exact"},{"name":"isolated cleft of the ala nasi","type":"exact"},{"name":"isolated coloboma of the nose","type":"exact"}],"termid":"MONDO:0015414","xrefs":{"Monarch":{"xref_id":"0015414"}}}


id: PBO:0048373
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GRB2 associated regulator of MAPK1 subtype 1","termid":"PBO:0048373"}


id: PBO:0070860
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L13 pseudogene 13","termid":"PBO:0070860"}


id: GO:0008819
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: cobinamide + ATP = cobinamide phosphate + ADP. This reaction is the phosphorylation of the hydroxyl group of the 1-amino-2-propanol residue of cobinamide, in the presence of ATP, to form cobinamide phosphate.","definition_xrefs":["PMID:1655696"],"gene_count":0,"genotype_count":0,"name":"obsolete cobinamide kinase activity (obsolete GO:0008819)","termid":"GO:0008819"}


id: SO:0001267
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A gene encoding a small noncoding RNA that participates in the processing or chemical modifications of many RNAs, including ribosomal RNAs and spliceosomal RNAs.","direct_ancestors":[{"relation_name":"has_quality","term_name":"snoRNA_encoding","termid":"SO:0000578"},{"relation_name":"is_a","term_name":"sncRNA_gene","termid":"SO:0002342"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"snoRNA_gene","synonyms":[{"name":"snoRNA gene","type":"exact"}],"termid":"SO:0001267"}


id: MONDO:0060457
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"autoinflammation with arthritis and dyskeratosis","secondary_identifiers":["MEDGEN:1380109","UMLS:C4479278","OMIM:617388"],"synonyms":[{"name":"AIADK","type":"related"},{"name":"AUTOINFLAMMATION with arthritis and dyskeratosis","type":"related"}],"termid":"MONDO:0060457","xrefs":{"Monarch":{"xref_id":"0060457"}}}


id: FYPO:0002155
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which chromosome structure is normal (i.e. indistinguishable from wild type) at the telomeric regions. Telomere structure refers to the position, shape, arrangement and connectivity of DNA and associated proteins in the telomeric region.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal telomere morphology during vegetative growth","termid":"FYPO:0006513"},{"relation_name":"is_a","term_name":"normal telomere structure","termid":"FYPO:0006514"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000257","FYPO:0001320"],"is_obsolete":false,"name":"normal telomere structure during vegetative growth","synonyms":[{"name":"normal chromosome structure at telomere during vegetative growth","type":"exact"},{"name":"normal chromosome structure at telomeric region during vegetative growth","type":"exact"},{"name":"normal telomere structure during mitotic cell cycle","type":"related"},{"name":"normal telomeric region structure during vegetative growth","type":"exact"}],"termid":"FYPO:0002155"}


id: GO:0032481
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.","definition_xrefs":["GOC:add","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cytokine production","termid":"GO:0001819"},{"relation_name":"is_a","term_name":"regulation of type I interferon production","termid":"GO:0032479"},{"relation_name":"positively_regulates","term_name":"type I interferon production","termid":"GO:0032606"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"positive regulation of type I interferon production","secondary_identifiers":["Reactome:R-HSA-1834949"],"synonyms":[{"name":"activation of type I interferon production","type":"narrow"},{"name":"positive regulation of type I IFN production","type":"exact"},{"name":"stimulation of type I interferon production","type":"narrow"},{"name":"up regulation of type I interferon production","type":"exact"},{"name":"up-regulation of type I interferon production","type":"exact"},{"name":"upregulation of type I interferon production","type":"exact"}],"termid":"GO:0032481"}


id: MONDO:0012443
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"intracranial berry aneurysm","termid":"MONDO:0016483"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aneurysm, intracranial berry, 4","secondary_identifiers":["UMLS:C1857749","OMIM:610213","DOID:0080967","MESH:C565700","GARD:18323","MEDGEN:341838"],"synonyms":[{"name":"ANIB4","type":"exact"},{"name":"aneurysm, intracranial BERRY, 4","type":"related"}],"termid":"MONDO:0012443","xrefs":{"Monarch":{"xref_id":"0012443"}}}


id: MONDO:0007449
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Dermo-odonto dysplasia belongs to the group of tricho-odonto-onychial dysplasias. It is characterized by signs of variable severity: dry and thin skin, dental anomalies, nail alteration and trichodysplasia. Fourteen cases have been described so far. Autosomal dominant transmission is likely.","definition_xrefs":["Orphanet:1660"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ectodermal dysplasia syndrome","termid":"MONDO:0019287"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"dermo-odonto dysplasia","secondary_identifiers":["MESH:C565103","GARD:1816","MEDGEN:377602","SCTID:721091003","UMLS:C1852144","OMIM:125640"],"synonyms":[{"name":"DERMOODONTODYSPLASIA","type":"related"},{"name":"dermo odontodysplasia","type":"related"},{"name":"dermo-odonto dysplasia","type":"exact"},{"name":"dermo-odonto-dysplasia","type":"related"},{"name":"dermoodonto dysplasia","type":"related"},{"name":"ectodermal dysplasia, hair-nail-Tooth type","type":"related"}],"termid":"MONDO:0007449","xrefs":{"Monarch":{"xref_id":"0007449"}}}


id: MONDO:0002864
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A malignant mesenchymal tumor with skeletal muscle differentiation affecting the anus.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"rectum rhabdomyosarcoma","termid":"MONDO:0002853"},{"relation_name":"is_a","term_name":"anus sarcoma","termid":"MONDO:0002865"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0004335"],"is_obsolete":false,"name":"anus rhabdomyosarcoma","secondary_identifiers":["DOID:4066","UMLS:C1332276","NCIT:C5610","MEDGEN:231065"],"synonyms":[{"name":"anal rhabdomyosarcoma","type":"exact"},{"name":"anus rhabdomyosarcoma (disease)","type":"exact"},{"name":"rhabdomyosarcoma (disease) of anus","type":"exact"},{"name":"rhabdomyosarcoma of anus","type":"exact"},{"name":"rhabdomyosarcoma of the anus","type":"exact"}],"termid":"MONDO:0002864","xrefs":{"Monarch":{"xref_id":"0002864"}}}


