# terms

id: GO:0033095
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A membrane-bounded storage granule found in cells of the aleurone layer in plants; contains either a protein matrix, protein-carbohydrate bodies and/or globoids. Aleurone grains are formed by the vacuole, rough endoplasmic reticulum and dictyosomes.","definition_xrefs":["PMID:22452734","Wikipedia:Aleurone"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytoplasmic vesicle","termid":"GO:0031410"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0031410"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0005737","GO:0031410"],"is_obsolete":false,"name":"aleurone grain","synonyms":[{"name":"aleurone body","type":"exact"}],"termid":"GO:0033095"}


id: PBO:0003335
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"endoribonuclease (predicted)","termid":"PBO:0003335"}


id: GO:1903134
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any trehalose catabolic process that is involved in cellular response to stress.","definition_xrefs":["GOC:TermGenie","PMID:15965643","GO_REF:0000060"],"gene_count":0,"genotype_count":0,"name":"obsolete trehalose catabolic process involved in cellular response to stress (obsolete GO:1903134)","synonyms":[{"name":"mycose catabolic process involved in cellular response to stress","type":"exact"},{"name":"mycose catabolism involved in cellular response to stress","type":"exact"},{"name":"mykose catabolic process involved in cellular response to stress","type":"exact"},{"name":"mykose catabolism involved in cellular response to stress","type":"exact"},{"name":"trehalose breakdown involved in cellular response to stress","type":"exact"},{"name":"trehalose catabolism involved in cellular response to stress","type":"exact"},{"name":"trehalose degradation involved in cellular response to stress","type":"exact"}],"termid":"GO:1903134"}


id: FYPO:0002469
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"OBSOLETE. A cell population phenotype in which a cell undergoes one or a few rounds of cell division before cells die, resulting in the formation a colony that contains only a few inviable cells that are longer than normal and taper at one end to a diameter smaller than the other. Up to 6 rounds of cell division (generating 64 cells) may be observed, but 3 divisions or fewer is more typical.","definition_xrefs":["PomBase:mah","PomBase:vw"],"gene_count":0,"genotype_count":0,"name":"obsolete inviable microcolony, elongated tapered cells (obsolete FYPO:0002469)","synonyms":[{"name":"inviable microcolony, elongated bottle/skittle cells","type":"exact"},{"name":"inviable microcolony, elongated skittle-shaped cells","type":"exact"},{"name":"inviable microcolony, elongated tapered vegetative cells","type":"exact"}],"termid":"FYPO:0002469"}


id: PBO:0079886
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uroplakin 3B like 3, pseudogene","termid":"PBO:0079886"}


id: GO:0005366
data:
  {"annotated_genes":["SJAG_04506","SJAG_03595"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[73767,74764],"is_not":false,"summary":null,"term":"GO:0005366"}]},"cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: myo-inositol(out) + H+(out) = myo-inositol(in) + H+(in).","definition_xrefs":["TC:2.A.1.1.8"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myo-inositol transmembrane transporter activity","termid":"GO:0005365"},{"relation_name":"is_a","term_name":"solute:proton symporter activity","termid":"GO:0015295"}],"gene_count":2,"genes_by_uniquename":{"SJAG_03595":null,"SJAG_04506":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0003674","GO:0022857","GO:0005215"],"is_obsolete":false,"name":"myo-inositol:proton symporter activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["Reactome:R-HSA-429101","RHEA:60364"],"synonyms":[{"name":"hydrogen/myo-inositol transporter activity","type":"broad"},{"name":"myo-inositol:hydrogen symporter activity","type":"exact"}],"termid":"GO:0005366","terms_by_termid":{"GO:0005366":null}}


id: PBO:0117119
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SLC35F4 antisense RNA 1","termid":"PBO:0117119"}


id: MONDO:0029051
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. Autosomal recessive nail dysplasia is a rare, isolated nail anomaly characterized by claw-shaped, thick, hyperplastic, hard and hyperpigmented nails, subungual hyperkeratosis, onycholysis and slow nail growth. Variable degree of disease severity has been reported. [Orphanet:280654]","definition_xrefs":["Orphanet:280654"],"gene_count":0,"genotype_count":0,"name":"obsolete autosomal recessive nail dysplasia (obsolete MONDO:0029051)","secondary_identifiers":["ICD10CM:Q84.6"],"termid":"MONDO:0029051","xrefs":{"Monarch":{"xref_id":"0029051"}}}


id: MONDO:0004325
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare benign tumor that arises from the testis and is characterized by the presence of lipid-rich neoplastic spindle cells.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"testicular sex cord-stromal neoplasm","termid":"MONDO:0003125"},{"relation_name":"is_a","term_name":"thecoma","termid":"MONDO:0037252"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"testicular thecoma","secondary_identifiers":["DOID:7676","NCIT:C39952","MEDGEN:308260","UMLS:C1515299"],"synonyms":[{"name":"testis thecoma","type":"exact"},{"name":"thecoma of testis","type":"exact"}],"termid":"MONDO:0004325","xrefs":{"Monarch":{"xref_id":"0004325"}}}


id: MONDO:0044649
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"heart disorder","termid":"MONDO:0005267"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-variable intellectual disability syndrome","termid":"MONDO:0015160"},{"relation_name":"is_a","term_name":"dysostosis","termid":"MONDO:0018234"},{"relation_name":"is_a","term_name":"congenital limb malformation","termid":"MONDO:0019054"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"},{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005497","MONDO:0005267"],"is_obsolete":false,"name":"omphalocele-diaphragmatic hernia-cardiovascular anomalies-radial ray defect syndrome","secondary_identifiers":["GARD:10354","Orphanet:496693"],"synonyms":[{"name":"Gershoni-Baruch syndrome","type":"exact"}],"termid":"MONDO:0044649","xrefs":{"Monarch":{"xref_id":"0044649"}}}


id: PBO:0004166
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"guanyl-nucleotide exchange factor Vps901 (predicted)","termid":"PBO:0004166"}


id: GO:1900559
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of austinol.","definition_xrefs":["GOC:di","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"catabolic process","termid":"GO:0009056"},{"relation_name":"is_a","term_name":"austinol metabolic process","termid":"GO:1900558"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"austinol catabolic process","synonyms":[{"name":"austinol breakdown","type":"exact"},{"name":"austinol catabolism","type":"exact"},{"name":"austinol degradation","type":"exact"}],"termid":"GO:1900559"}


id: GO:0045092
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that binds interleukin-18; comprises an alpha and a beta subunit.","definition_xrefs":["GOC:mah","PMID:12759435"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plasma membrane signaling receptor complex","termid":"GO:0098802"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005886"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0005886","GO:0032991"],"is_obsolete":false,"name":"interleukin-18 receptor complex","synonyms":[{"name":"IL-18 receptor complex","type":"exact"}],"termid":"GO:0045092"}


id: MONDO:0005123
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete Hibiscus chlorotic ringspot virus infection (obsolete MONDO:0005123)","termid":"MONDO:0005123","xrefs":{"Monarch":{"xref_id":"0005123"}}}


id: GO:0019242
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"methylglyoxal metabolic process","termid":"GO:0009438"},{"relation_name":"is_a","term_name":"ketone biosynthetic process","termid":"GO:0042181"},{"relation_name":"is_a","term_name":"aldehyde biosynthetic process","termid":"GO:0046184"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0044281","GO:0008150"],"is_obsolete":false,"name":"methylglyoxal biosynthetic process","synonyms":[{"name":"methylglyoxal anabolism","type":"exact"},{"name":"methylglyoxal biosynthesis","type":"exact"},{"name":"methylglyoxal formation","type":"exact"},{"name":"methylglyoxal synthesis","type":"exact"}],"termid":"GO:0019242"}


id: GO:0102804
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: oripavine + 2-oxoglutarate + O2 = morphinone + formaldehyde + succinate + carbon dioxide.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete oripavine 6-O-demethylase activity (obsolete GO:0102804)","termid":"GO:0102804"}


id: GO:0019204
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: phosphopolynucleotide + H2O = polynucleotide + phosphate.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete nucleotide phosphatase activity (obsolete GO:0019204)","synonyms":[{"name":"nucleotide phosphatase activity","type":"exact"}],"termid":"GO:0019204"}


id: GO:0004076
data:
  {"annotated_genes":["SJAG_01935"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[81075],"is_not":false,"summary":null,"term":"GO:0004076"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: (4R,5S)-dethiobiotin + [sulfur carrier]-SH + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = [sulfur carrier]-H + biotin + 2 5'-deoxyadenosine + 2 L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin].","definition_xrefs":["RHEA:22060","EC:2.8.1.6"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sulfurtransferase activity","termid":"GO:0016783"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01935":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016782"}],"interesting_parent_ids":["GO:0003674","GO:0016782","GO:0003824","GO:0016740"],"is_obsolete":false,"name":"biotin synthase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["MetaCyc:2.8.1.6-RXN","KEGG_REACTION:R01078"],"synonyms":[{"name":"biotin synthetase activity","type":"related"},{"name":"dethiobiotin:sulfur sulfurtransferase activity","type":"related"}],"termid":"GO:0004076","terms_by_termid":{"GO:0004076":null}}


id: PBO:0117030
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"LRRC32 antisense RNA 1","termid":"PBO:0117030"}


id: FYPO:0004947
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of cardiolipin measured in membranes that form the mitochondrial envelope is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal cellular cardiolipin level","termid":"FYPO:0005590"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000257","FYPO:0001312","FYPO:0000002"],"is_obsolete":false,"name":"normal mitochondrial membrane cardiolipin level","synonyms":[{"name":"normal level of cardiolipin in mitochondrial membrane","type":"exact"},{"name":"normal mitochondrial cardiolipin level","type":"exact"},{"name":"normal mitochondrial envelope cardiolipin level","type":"related"},{"name":"normal mitochondrial membrane cardiolipin level during mitotic cell cycle","type":"related"},{"name":"normal mitochondrial membrane cardiolipin level during vegetative growth","type":"exact"}],"termid":"FYPO:0004947"}


id: PBO:0048338
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glyceraldehyde 3 phosphate dehydrogenase pseudogene 49","termid":"PBO:0048338"}


id: MONDO:0016338
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"dilated cardiomyopathy","termid":"MONDO:0005021"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"non-familial dilated cardiomyopathy","secondary_identifiers":["Orphanet:217629","GARD:20530","icd11.foundation:1782708952","MEDGEN:1843057","UMLS:C5681849"],"termid":"MONDO:0016338","xrefs":{"Monarch":{"xref_id":"0016338"}}}


id: PBO:0055203
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2628","termid":"PBO:0055203"}


id: MONDO:0035235
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare subtype of pyoderma gangrenosum disease characterized by rapidly progressive, single or multiple, painful, aseptic ulcers which present overhanging, violaceous and undermined borders, surrounding induration and erythema, and granulation tissue (occasionally necrotic tissue and/or a purulent exudate) at the base, mainly affecting the legs (but other body surfaces may also be involved), leading to chronic ulcerations and often regressing with cribriform mutilating scars. The disease presents a chronic relapsing course and systemic features (e.g. fever, malaise, arthralgia, myalgia) may be associated.","definition_xrefs":["Orphanet:538863"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pyoderma gangrenosum","termid":"MONDO:0018824"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"classic pyoderma gangrenosum","secondary_identifiers":["ICD10CM:L88","MEDGEN:1814456","UMLS:C5680157","GARD:22220"],"synonyms":[{"name":"Ulcerative pyoderma gangrenosum","type":"exact"}],"termid":"MONDO:0035235","xrefs":{"Monarch":{"xref_id":"0035235"}}}


id: PR:O74173
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An elongation factor 1-beta that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO04800","PRO:DNx","PANTHER:PTHR11595:SF7"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"elongation factor 1-beta (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC1450.04","secondary_identifiers":["UniProtKB:O74173"],"synonyms":[{"name":"EF-1-beta (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-EEF1B2","type":"exact"}],"termid":"PR:O74173"}


id: SO:0000612
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"The polypyrimidine tract is one of the cis-acting sequence elements directing intron removal in pre-mRNA splicing.","direct_ancestors":[{"relation_name":"is_a","term_name":"spliceosomal_intron_region","termid":"SO:0000841"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"polypyrimidine_tract","secondary_identifiers":["http://en.wikipedia.org/wiki/Polypyrimidine_tract"],"synonyms":[{"name":"polypyrimidine tract","type":"exact"}],"termid":"SO:0000612"}


id: PBO:0054237
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1619","termid":"PBO:0054237"}


id: PR:P0CS85
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPBCPT2R1.03 gene.","definition_xrefs":["PRO:DNx","UniProtKB:P0CS85"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein CPT2R1.03 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBCPT2R1.03","synonyms":[{"name":"Spom972h-SPBCPT2R1.03","type":"exact"}],"termid":"PR:P0CS85"}


id: GO:0002542
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates Factor XII (Hageman factor). Factor XII is a protein synthesized by the liver that circulates in an inactive form until it encounters collagen or basement membrane or activated platelets (as occurs at the site of endothelial injury). Factor XII then undergoes a conformational change (becoming factor XIIa), exposing an active serine center that can subsequently cleave protein substrates and activate a variety of mediator systems. Factor XII is a participant in the clotting cascade as well as the kinin cascade.","definition_xrefs":["ISBN:0721601871","GOC:jal"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of acute inflammatory response","termid":"GO:0002673"},{"relation_name":"is_a","term_name":"positive regulation of protein processing","termid":"GO:0010954"},{"relation_name":"part_of","term_name":"plasma kallikrein-kinin cascade","termid":"GO:0002353"},{"relation_name":"positively_regulates","term_name":"activation of plasma proteins involved in acute inflammatory response","termid":"GO:0002541"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0010467"},{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"regulates","termid":"GO:0051604"},{"rel_name":"part_of","termid":"GO:0051604"},{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0051604"}],"interesting_parent_ids":["GO:0010467","GO:0008150","GO:0051604"],"is_obsolete":false,"name":"Factor XII activation","synonyms":[{"name":"Hageman factor activation","type":"exact"}],"termid":"GO:0002542"}


id: SO:0001664
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A discontinuous core element of RNA polymerase II transcribed genes, situated downstream of the TSS. It is composed of three sub elements: SI, SII and SIII.","definition_xrefs":["PMID:16858867"],"direct_ancestors":[{"relation_name":"is_a","term_name":"core_eukaryotic_promoter_element","termid":"SO:0001660"},{"relation_name":"part_of","term_name":"RNApol_II_core_promoter","termid":"SO:0001669"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DCE","synonyms":[{"name":"downstream core element","type":"related"}],"termid":"SO:0001664"}


id: GO:0002920
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of a humoral immune response.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of immune response","termid":"GO:0050776"},{"relation_name":"regulates","term_name":"humoral immune response","termid":"GO:0006959"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of humoral immune response","termid":"GO:0002920"}


id: PBO:0012257
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proteiasome complex subunit Ecm29","termid":"PBO:0012257"}


id: PR:O14155
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A UPF0047 protein YjbQ that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO01063","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UPF0047 protein C4A8.02c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC4A8.02c","secondary_identifiers":["UniProtKB:O14155"],"synonyms":[{"name":"Spom972h-yjbQ","type":"exact"}],"termid":"PR:O14155"}


id: PBO:0044096
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cancer/testis antigen family 47 member A4","termid":"PBO:0044096"}


id: FYPO:0003160
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell morphology phenotype in which a cell is elongated, i.e. has a greater length and length:diameter ratio than normal, when the cell is in a culture in stationary phase.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"elongated cell","termid":"FYPO:0000017"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000005"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"has_part","termid":"FYPO:0000005"}],"interesting_parent_ids":["FYPO:0000005","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"elongated cell during stationary phase","synonyms":[{"name":"long cell during stationary phase","type":"exact"}],"termid":"FYPO:0003160"}


id: GO:0071144
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex composed of SMAD family proteins, a transcription factor complex which binds to the promoters of target genes and recruits co-activators and histone acetyltransferases, facilitating transcription. Phosphorylation of the non-SMAD4 subunit(s) enables binding of SMAD4 to form heteromeric complexes that enter the nucleus to initiate gene transcription. DNA-binding specificity is conferred by other transcription factors binding to SMAD complexes. Interactions with coactivators or corepressors modulate their transcriptional activity. Can be heterotrimeric or heterodimeric.","definition_xrefs":["PMID:16322555","PMID:9670020","GOC:mah","PMID:15350224","PMID:9389648","GOC:bhm","PMID:11779505"],"direct_ancestors":[{"relation_name":"is_a","term_name":"SMAD protein complex","termid":"GO:0071141"},{"relation_name":"is_a","term_name":"RNA polymerase II transcription regulator complex","termid":"GO:0090575"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005634"}],"interesting_parent_ids":["GO:0032991","GO:0005634","GO:0005575"],"is_obsolete":false,"name":"heteromeric SMAD protein complex","secondary_identifiers":["GO:0071145","GO:0071146"],"synonyms":[{"name":"SMAD1-SMAD4 protein complex","type":"narrow"},{"name":"SMAD2-SMAD3-SMAD4 protein complex","type":"narrow"},{"name":"SMAD2-SMAD4 protein complex","type":"narrow"},{"name":"SMAD3-SMAD4 protein complex","type":"narrow"}],"termid":"GO:0071144"}


id: GO:0007268
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.","definition_xrefs":["MeSH:D009435","GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anterograde trans-synaptic signaling","termid":"GO:0098916"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"chemical synaptic transmission","secondary_identifiers":["Reactome:R-HSA-9620244","Reactome:R-HSA-451308","Reactome:R-HSA-9619229","Reactome:R-HSA-451307","Reactome:R-HSA-9619483","Reactome:R-HSA-442742","Reactome:R-HSA-442729","Wikipedia:Neurotransmission","Reactome:R-HSA-112316","Reactome:R-HSA-442720"],"synonyms":[{"name":"neurotransmission","type":"related"},{"name":"signal transmission across a synapse","type":"broad"},{"name":"synaptic transmission","type":"broad"}],"termid":"GO:0007268"}


id: PBO:0087552
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of RNase MRP, nuclear RNase P and telomerase; forms a soluble heterodimer with Pop6p that binds P3 domain of RNase MRP and RNase P RNAs; RNase MRP cleaves pre-rRNA, nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs, while telomerase replenishes telomeric DNA","termid":"PBO:0087552"}


id: PBO:0113376
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative cysteine synthase; localized to the mitochondrial outer membrane; interacts with TCD1 and TCD2, likely forming a complex","termid":"PBO:0113376"}


id: GO:0010745
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.","definition_xrefs":["GOC:add","GOC:BHF","GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of macrophage derived foam cell differentiation","termid":"GO:0010743"},{"relation_name":"is_a","term_name":"negative regulation of cell differentiation","termid":"GO:0045596"},{"relation_name":"negatively_regulates","term_name":"macrophage derived foam cell differentiation","termid":"GO:0010742"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of macrophage derived foam cell differentiation","termid":"GO:0010745"}


id: PBO:0064368
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphomannomutase 2","termid":"PBO:0064368"}


id: GO:0010487
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: S-adenosyl-L-methioninamine + spermidine = S-methyl-5'-thioadenosine + thermospermine + H+.","definition_xrefs":["PMID:17560575","EC:2.5.1.79","MetaCyc:RXN-11190"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transferase activity, transferring alkyl or aryl (other than methyl) groups","termid":"GO:0016765"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016765"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016765","GO:0016740","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"thermospermine synthase activity","secondary_identifiers":["RHEA:30515"],"termid":"GO:0010487"}


id: GO:0035753
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process involved in sustaining the fidelity and copy number of DNA trinucleotide repeats. DNA trinucleotide repeats are naturally occurring runs of three base-pairs.","definition_xrefs":["GOC:rb","SO:0000291","PMID:21347277"],"direct_ancestors":[{"relation_name":"is_a","term_name":"maintenance of DNA repeat elements","termid":"GO:0043570"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006259"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006259","GO:0008150"],"is_obsolete":false,"name":"maintenance of DNA trinucleotide repeats","termid":"GO:0035753"}


id: PBO:0070574
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L7a pseudogene 40","termid":"PBO:0070574"}


id: PBO:0060665
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NDC1 transmembrane nucleoporin","termid":"PBO:0060665"}


id: GO:1905094
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway.","definition_xrefs":["PMID:25084135","GOC:TermGenie","GO_REF:0000058","GOC:bc","GOC:BHF_miRNA","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of signal transduction","termid":"GO:0009966"},{"relation_name":"regulates","term_name":"apolipoprotein A-I-mediated signaling pathway","termid":"GO:0038027"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"regulation of apolipoprotein A-I-mediated signaling pathway","synonyms":[{"name":"regulation of apolipoprotein A-I-mediated signalling pathway","type":"exact"}],"termid":"GO:1905094"}


id: PBO:0062608
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 10 subfamily R member 3 pseudogene","termid":"PBO:0062608"}


id: PBO:0025538
data:
  {"annotation_feature_type":"gene","cv_name":"disease_associated","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acatalasemia","termid":"PBO:0025538"}


id: PBO:0080397
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"VPS26C pseudogene 1","termid":"PBO:0080397"}


id: GO:0046447
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving terpenoid indole alkaloids, compounds formed from the condensation of tryptamine (derived from tryptophan) and secologanin (derived from geranyl pyrophosphate).","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"indole alkaloid metabolic process","termid":"GO:0035834"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"terpenoid indole alkaloid metabolic process","synonyms":[{"name":"terpenoid indole alkaloid metabolism","type":"exact"}],"termid":"GO:0046447"}


id: MONDO:0100173
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An inherited susceptibility or predisposition to developing leukemia, acute myeloid.","definition_xrefs":["MONDO:patterns/inherited_susceptibility"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary neoplastic syndrome","termid":"MONDO:0015356"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leukemia, acute myeloid, susceptibility to","secondary_identifiers":["MEDGEN:477590","UMLS:C3275959"],"termid":"MONDO:0100173","xrefs":{"Monarch":{"xref_id":"0100173"}}}


id: PBO:0026677
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-resistance_to_sodium_dodecyl_sulfate","termid":"PBO:0026677"}


id: PBO:0077311
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein 50A","termid":"PBO:0077311"}


id: PBO:0113282
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Poly(A) binding protein; interacts with the cleavage factor complex CF I, mediates interactions between the 5' cap structure and the 3' mRNA poly(A) tail, involved in control of poly(A) tail length, interacts with translation factor eIF-4G; stimulates, but is not required for the deadenylation activity of the Pan2p-Pan3p poly(A)-ribonuclease complex; role in preventing L-A mycovirus pathogenesis","termid":"PBO:0113282"}


id: MONDO:0006009
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Encephalitis resulting from viral infection.","definition_xrefs":["NCIT:C35302"],"direct_ancestors":[{"relation_name":"is_a","term_name":"infectious encephalitis","termid":"MONDO:0020067"},{"relation_name":"is_a","term_name":"viral infection of central nervous system","termid":"MONDO:0024318"},{"relation_name":"is_a","term_name":"primary viral infectious disease","termid":"MONDO:0100329"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"viral encephalitis","secondary_identifiers":["GARD:19433","MedDRA:10058805","EFO:0007538","MEDGEN:116719","SCTID:34476008","DOID:646","Orphanet:98252","UMLS:C0243010"],"synonyms":[{"name":"Viruses caused encephalitis","type":"exact"},{"name":"Viruses encephalitis","type":"exact"},{"name":"viral encephalitis","type":"exact"}],"termid":"MONDO:0006009","xrefs":{"Monarch":{"xref_id":"0006009"}}}


id: GO:1904372
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of protein localization to actin cortical patch.","definition_xrefs":["GOC:TermGenie","PMID:18216290","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of protein localization to actin cortical patch","termid":"GO:1904370"},{"relation_name":"is_a","term_name":"positive regulation of protein localization to cell cortex","termid":"GO:1904778"},{"relation_name":"positively_regulates","term_name":"protein localization to actin cortical patch","termid":"GO:0044379"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of protein localization to actin cortical patch","synonyms":[{"name":"activation of protein localisation to actin cortical patch","type":"narrow"},{"name":"activation of protein localization to actin cortical patch","type":"narrow"},{"name":"positive regulation of protein localisation to actin cortical patch","type":"exact"},{"name":"up regulation of protein localisation to actin cortical patch","type":"exact"},{"name":"up regulation of protein localization to actin cortical patch","type":"exact"},{"name":"up-regulation of protein localisation to actin cortical patch","type":"exact"},{"name":"up-regulation of protein localization to actin cortical patch","type":"exact"},{"name":"upregulation of protein localisation to actin cortical patch","type":"exact"},{"name":"upregulation of protein localization to actin cortical patch","type":"exact"}],"termid":"GO:1904372"}


id: GO:0140976
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The cellular processes and signaling pathways by which a cell responds to disruption of the integrity of its plasma membrane by another organism. Some toxins produced by other organisms can form pores in membranes, or affect the membrane permeability.","definition_xrefs":["PMID:17234446","PMID:21518219"],"direct_ancestors":[{"relation_name":"is_a","term_name":"defense response to symbiont","termid":"GO:0140546"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"host defense response against symbiont-mediated perturbation of plasma membrane integrity","synonyms":[{"name":"defense response against disruption of plasma membrane integrity","type":"exact"},{"name":"defense response against perturbation of plasma membrane integrity","type":"related"}],"termid":"GO:0140976"}


id: GO:0016138
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glycoside metabolic process","termid":"GO:0016137"},{"relation_name":"is_a","term_name":"glycosyl compound biosynthetic process","termid":"GO:1901659"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"glycoside biosynthetic process","secondary_identifiers":["GO:0016141"],"synonyms":[{"name":"O-glycoside anabolism","type":"exact"},{"name":"O-glycoside biosynthesis","type":"exact"},{"name":"O-glycoside biosynthetic process","type":"exact"},{"name":"O-glycoside formation","type":"exact"},{"name":"O-glycoside synthesis","type":"exact"},{"name":"glycoside anabolism","type":"exact"},{"name":"glycoside biosynthesis","type":"exact"},{"name":"glycoside formation","type":"exact"},{"name":"glycoside synthesis","type":"exact"}],"termid":"GO:0016138"}


id: PBO:0086730
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative protein of unknown function; not conserved in closely related Saccharomyces species; 98% of ORF overlaps the verified gene YPT6; deletion causes a vacuolar protein sorting defect; decreased levels of protein in enolase deficient mutant","termid":"PBO:0086730"}


id: PBO:0002464
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"actin cortical patch component, with EF hand and WH2 motif Panl (predicted)","termid":"PBO:0002464"}


id: MONDO:0003845
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare benign adipose tissue neoplasm of the corpus callosum.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cerebral hemisphere lipoma","termid":"MONDO:0003843"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"corpus callosum lipoma","secondary_identifiers":["MEDGEN:272510","NCIT:C5438","UMLS:C1333160","DOID:6294"],"synonyms":[{"name":"corpus callosum lipoma","type":"exact"},{"name":"lipoma of corpus callosum","type":"exact"},{"name":"lipoma of the corpus callosum","type":"exact"}],"termid":"MONDO:0003845","xrefs":{"Monarch":{"xref_id":"0003845"}}}


id: PR:O74851
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- adg3 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O74851"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"secreted beta-glucosidase adg3 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC18.01c","synonyms":[{"name":"Spom972h-adg3","type":"exact"}],"termid":"PR:O74851"}


id: PBO:0080762
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"X-linked inhibitor of apoptosis pseudogene 1","termid":"PBO:0080762"}


id: PBO:0027231
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-fragmented_DNA_during_stationary_phase","termid":"PBO:0027231"}


id: GO:0004358
data:
  {"annotated_genes":["SJAG_01592"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[66639],"is_not":false,"summary":null,"term":"GO:0004358"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: N2-acetyl-L-ornithine + L-glutamate = N-acetyl-L-glutamate + L-ornithine.","definition_xrefs":["RHEA:15349"],"direct_ancestors":[{"relation_name":"is_a","term_name":"L-amino-acid N-acetyltransferase activity","termid":"GO:0140085"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01592":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016746"}],"interesting_parent_ids":["GO:0003824","GO:0016746","GO:0016740","GO:0003674"],"is_obsolete":false,"name":"L-glutamate N-acetyltransferase activity, acting on acetyl-L-ornithine as donor","references_by_uniquename":{"GO_REF:0000003":null},"secondary_identifiers":["KEGG_REACTION:R02282","MetaCyc:GLUTAMATE-N-ACETYLTRANSFERASE-RXN","EC:2.3.1.35"],"synonyms":[{"name":"2-N-acetyl-L-ornithine:L-glutamate N-acetyltransferase activity","type":"related"},{"name":"L-glutamate N-acetyltransferase activity","type":"broad"},{"name":"N-acetyl-L-glutamate synthetase activity","type":"broad"},{"name":"N-acetylglutamate synthase activity","type":"broad"},{"name":"N-acetylglutamate synthetase activity","type":"broad"},{"name":"N2-acetyl-L-ornithine:L-glutamate N-acetyltransferase activity","type":"related"},{"name":"acetyl-L-glutamate:acetyl-L-ornithine transacetylase activity","type":"exact"},{"name":"acetylglutamate synthetase activity","type":"related"},{"name":"acetylglutamate-acetylornithine transacetylase activity","type":"related"},{"name":"acetylglutamic synthetase activity","type":"related"},{"name":"acetylglutamic-acetylornithine transacetylase activity","type":"related"},{"name":"acetylornithinase activity","type":"broad"},{"name":"acetylornithine glutamate acetyltransferase activity","type":"related"},{"name":"alpha-N-acetyl-L-ornithine:L-glutamate N-acetyltransferase activity","type":"related"},{"name":"glutamate N-acetyltransferase activity","type":"broad"},{"name":"glutamate acetyltransferase activity","type":"related"},{"name":"ornithine acetyltransferase activity","type":"related"},{"name":"ornithine transacetylase activity","type":"related"}],"termid":"GO:0004358","terms_by_termid":{"GO:0004358":null}}


id: MONDO:0018869
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Cobblestone lissencephaly is a rare central nervous system malformation which includes a group of diseases that are characterized by a bumpy (or pebbled) appearance of the cerebral cortex, associated with a thickened cortex, reduction in normal sulcation, ventriculomegaly and reduced, abnormal white matter, as well as brainstem and cerebellum hypoplasia and corpus callosum agenesis. Patients generally present variable degrees of developmental delay, hypotonia and ocular abnomalities, however muscular and ocular involvement may be absent.","definition_xrefs":["Orphanet:51577"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lissencephaly spectrum disorders","termid":"MONDO:0018838"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320"],"is_obsolete":false,"name":"cobblestone lissencephaly","secondary_identifiers":["MESH:D054222","GARD:3277","UMLS:C0431376","NANDO:1201072","MEDGEN:96562","SCTID:253149002"],"synonyms":[{"name":"lissencephaly type 2","type":"exact"}],"termid":"MONDO:0018869","xrefs":{"Monarch":{"xref_id":"0018869"}}}


id: GO:0002428
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC class Ib protein complex on its cell surface. The peptide antigen may originate from an endogenous or exogenous protein. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E family.","definition_xrefs":["GOC:add","PMID:15928678"],"direct_ancestors":[{"relation_name":"is_a","term_name":"antigen processing and presentation via MHC class Ib","termid":"GO:0002475"},{"relation_name":"is_a","term_name":"antigen processing and presentation of peptide antigen","termid":"GO:0048002"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"antigen processing and presentation of peptide antigen via MHC class Ib","synonyms":[{"name":"peptide antigen processing and presentation via MHC class Ib","type":"exact"}],"termid":"GO:0002428"}


id: MONDO:0008539
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete distal arthrogryposis type 10 (obsolete MONDO:0008539)","termid":"MONDO:0008539","xrefs":{"Monarch":{"xref_id":"0008539"}}}


id: GO:0035177
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The movement of a larva through a feeding substrate whilst feeding on food.","definition_xrefs":["PMID:12848927"],"direct_ancestors":[{"relation_name":"is_a","term_name":"larval behavior","termid":"GO:0030537"},{"relation_name":"is_a","term_name":"foraging behavior","termid":"GO:0060756"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"larval foraging behavior","synonyms":[{"name":"larval foraging behaviour","type":"exact"}],"termid":"GO:0035177"}


id: PBO:0071408
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L31 pseudogene 14","termid":"PBO:0071408"}


id: GO:0010150
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The last stage of leaf development during which programmed degradation of macromolecules and nutrient recycling take place.","definition_xrefs":["PMID:17177638","PMID:34938309","ISBN:0387987819"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plant organ senescence","termid":"GO:0090693"},{"relation_name":"part_of","term_name":"leaf development","termid":"GO:0048366"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"leaf senescence","termid":"GO:0010150"}


id: GO:0072124
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of glomerular mesangial cell proliferation.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cell proliferation involved in kidney development","termid":"GO:1901722"},{"relation_name":"regulates","term_name":"glomerular mesangial cell proliferation","termid":"GO:0072110"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of glomerular mesangial cell proliferation","termid":"GO:0072124"}


id: GO:1902392
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of exodeoxyribonuclease activity.","definition_xrefs":["GOC:TermGenie","GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of exodeoxyribonuclease activity (obsolete GO:1902392)","termid":"GO:1902392"}


id: GO:0015092
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of ferric iron (Fe(III) or Fe3+) ions from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.","definition_xrefs":["PMID:1447137","GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ferric iron transmembrane transporter activity","termid":"GO:0015091"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0003674","GO:0022857","GO:0005215"],"is_obsolete":false,"name":"high-affinity ferric iron transmembrane transporter activity","synonyms":[{"name":"high affinity ferric uptake transmembrane transporter activity","type":"related"}],"termid":"GO:0015092"}


id: PBO:0031114
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_phenotype_during_exponential_phase","termid":"PBO:0031114"}


id: GO:0052343
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the production of phytoalexins as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation by organism of symbiont phytoalexin production (obsolete GO:0052343)","synonyms":[{"name":"positive regulation by organism of symbiont phytoalexin production","type":"exact"}],"termid":"GO:0052343"}


id: PBO:0086393
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative component of the TOR regulatory pathway; negative regulator of early meiotic gene expression; required, with Pmd1p, for growth under alkaline conditions; has an N-terminal kelch-like domain; MDS3 has a paralog, PMD1, that arose from the whole genome duplication","termid":"PBO:0086393"}


id: GO:0009819
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of prolonged deprivation of water that restores that organism to a normal (non-stressed) condition.","definition_xrefs":["GOC:lr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to water deprivation","termid":"GO:0009414"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"drought recovery","synonyms":[{"name":"drought tolerance","type":"related"}],"termid":"GO:0009819"}


id: GO:0160176
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of magnesium ion from cytosol to endoplasmic reticulum.","definition_xrefs":["PMID:38513662"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytosol to endoplasmic reticulum transport","termid":"GO:0046967"},{"relation_name":"is_a","term_name":"magnesium ion transmembrane transport","termid":"GO:1903830"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0055085","GO:0051179","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"magnesium ion transport from cytosol to endoplasmic reticulum","termid":"GO:0160176"}


id: PBO:0111850
data:
  {"annotation_feature_type":"gene","cv_name":"pombase_family_or_domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RecA family","termid":"PBO:0111850"}


id: MONDO:0000990
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Acute form of subendocardial myocardial infarction.","definition_xrefs":["MONDO:patterns/acute"],"direct_ancestors":[{"relation_name":"is_a","term_name":"subendocardial myocardial infarction","termid":"MONDO:0003674"},{"relation_name":"is_a","term_name":"acute myocardial infarction","termid":"MONDO:0004781"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"acute subendocardial myocardial infarction","secondary_identifiers":["ICD9:410.7","ICD9:410.70","ICD9:410.72","UMLS:C0264710","DOID:10266","ICD9:410.71","SCTID:70422006","MEDGEN:538778"],"synonyms":[{"name":"acute nontransmural infarction","type":"related"},{"name":"acute subendocardial infarction","type":"exact"},{"name":"subendocardial infarction acute myocardial infarction","type":"related"},{"name":"subendocardial myocardial infarction, acute","type":"exact"}],"termid":"MONDO:0000990","xrefs":{"Monarch":{"xref_id":"0000990"}}}


id: PBO:0069918
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1210, pseudogene","termid":"PBO:0069918"}


id: GO:0006424
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process of coupling glutamate to glutamyl-tRNA, catalyzed by glutamyl-tRNA synthetase. The glutamyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a glutamic acid-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.","definition_xrefs":["GOC:mcc","ISBN:0716730510"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tRNA aminoacylation for protein translation","termid":"GO:0006418"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006399"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006520"},{"rel_name":"part_of","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0006520","GO:0010467","GO:0008150","GO:0006399"],"is_obsolete":false,"name":"glutamyl-tRNA aminoacylation","termid":"GO:0006424"}


id: PBO:0000423
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein phosphatase regulatory subunit Reg1 (predicted)","termid":"PBO:0000423"}


id: MONDO:0006470
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A squamous cell carcinoma that arises from the mucosal lining of the tonsil and tends to metastasize early to the lymph nodes. It predominantly affects middle aged and elderly patients who have a history of alcohol and tobacco use. Patients may present with tonsillar swelling, sore throat, pain radiating to the ipsilateral ear, or a neck mass.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tonsil carcinoma","termid":"MONDO:0021337"},{"relation_name":"is_a","term_name":"oropharynx squamous cell carcinoma","termid":"MONDO:0044704"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0004992","MONDO:0004335"],"is_obsolete":false,"name":"tonsillar squamous cell carcinoma","secondary_identifiers":["DOID:0050920","MEDGEN:79101","EFO:1000597","NCIT:C8183","UMLS:C0280317"],"synonyms":[{"name":"SCC of the tonsil","type":"exact"},{"name":"SCC of tonsil","type":"exact"},{"name":"palatine tonsil squamous cell carcinoma","type":"exact"},{"name":"squamous cell carcinoma of the tonsil","type":"exact"},{"name":"squamous cell carcinoma of tonsil","type":"exact"},{"name":"tonsil SCC","type":"exact"},{"name":"tonsil squamous cell carcinoma","type":"exact"},{"name":"tonsillar SCC","type":"exact"}],"termid":"MONDO:0006470","xrefs":{"Monarch":{"xref_id":"0006470"}}}


id: PBO:0001603
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein phosphatase 2C Ptc4","termid":"PBO:0001603"}


id: PBO:0111864
data:
  {"annotation_feature_type":"gene","cv_name":"pombase_family_or_domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"C2 domain","termid":"PBO:0111864"}


id: GO:2000209
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of anoikis.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of apoptotic process","termid":"GO:0042981"},{"relation_name":"regulates","term_name":"anoikis","termid":"GO:0043276"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of anoikis","synonyms":[{"name":"regulation of detachment induced cell death","type":"exact"},{"name":"regulation of suspension induced apoptosis","type":"exact"}],"termid":"GO:2000209"}


id: PBO:0056514
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"muscleblind like splicing regulator 3","termid":"PBO:0056514"}


id: GO:0009788
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of abscisic acid (ABA) signaling.","definition_xrefs":["GOC:lr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of abscisic acid-activated signaling pathway","termid":"GO:0009787"},{"relation_name":"is_a","term_name":"negative regulation of signal transduction","termid":"GO:0009968"},{"relation_name":"is_a","term_name":"negative regulation of cellular response to alcohol","termid":"GO:1905958"},{"relation_name":"negatively_regulates","term_name":"abscisic acid-activated signaling pathway","termid":"GO:0009738"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"negative regulation of abscisic acid-activated signaling pathway","synonyms":[{"name":"down regulation of abscisic acid mediated signaling","type":"exact"},{"name":"down-regulation of abscisic acid mediated signaling","type":"exact"},{"name":"downregulation of abscisic acid mediated signaling","type":"exact"},{"name":"inhibition of abscisic acid mediated signaling","type":"narrow"},{"name":"negative regulation of abscisic acid mediated signaling pathway","type":"related"},{"name":"negative regulation of abscisic acid mediated signalling","type":"exact"}],"termid":"GO:0009788"}


id: PBO:0053293
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"LIMK2 pseudogene 1","termid":"PBO:0053293"}


id: GO:0009580
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete thylakoid (sensu Bacteria) (obsolete GO:0009580)","synonyms":[{"name":"thylakoid (sensu Bacteria)","type":"exact"}],"termid":"GO:0009580"}


id: PBO:0002673
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"splicing associated factor Saf3","termid":"PBO:0002673"}


id: PBO:0087294
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Single stranded DNA-binding protein found at TG1-3 telomere G-tails; key roles in regulation of telomerase, telomere end protection, conventional telomere replication; regulates telomere replication through recruitment of specific sub-complexes, essential function is telomere capping; forms homodimer via N-terminus; disruption of dimerization leads to short telomeres; autophagy and proteasome are involved in Cdc13p degradation; differentially phosphorylated through cell cycle","termid":"PBO:0087294"}


id: FYPO:0006368
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a normal (i.e. indistinguishable from wild type) portion of the centromeric region of the chromosome.","definition_xrefs":["PMID:29214404","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal chromatin organization","termid":"FYPO:0007940"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001312"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000257","FYPO:0001312","FYPO:0001320"],"is_obsolete":false,"name":"normal spatial extent of centromeric heterochromatin assembly","synonyms":[{"name":"normal spatial extent of centromeric heterochromatin assembly during mitotic cell cycle","type":"related"},{"name":"normal spatial extent of centromeric heterochromatin assembly during vegetative growth","type":"exact"},{"name":"normal spatial extent of centromeric heterochromatin formation","type":"exact"}],"termid":"FYPO:0006368"}


id: GO:0102004
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 3-(all-trans-octaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine = H+ + 2-methoxy-6-(all-trans-octaprenyl)phenol + S-adenosyl-L-homocysteine.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete 2-octaprenyl-6-hydroxyphenol methylase activity (obsolete GO:0102004)","termid":"GO:0102004"}


id: GO:0019504
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline.","definition_xrefs":["PMID:1804402","PMID:24520058","PMID:10689197"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amino-acid betaine catabolic process","termid":"GO:0006579"},{"relation_name":"is_a","term_name":"alkaloid catabolic process","termid":"GO:0009822"},{"relation_name":"is_a","term_name":"L-proline betaine metabolic process","termid":"GO:0019502"},{"relation_name":"is_a","term_name":"L-amino acid catabolic process","termid":"GO:0170035"},{"relation_name":"is_a","term_name":"non-proteinogenic amino acid catabolic process","termid":"GO:0170044"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006520"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0006520","GO:0044281"],"is_obsolete":false,"name":"L-proline betaine catabolic process","secondary_identifiers":["MetaCyc:P561-PWY"],"synonyms":[{"name":"stachydrine breakdown","type":"exact"},{"name":"stachydrine catabolic process","type":"exact"},{"name":"stachydrine catabolism","type":"exact"},{"name":"stachydrine degradation","type":"exact"}],"termid":"GO:0019504"}


id: GO:0019370
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"leukotriene metabolic process","termid":"GO:0006691"},{"relation_name":"is_a","term_name":"icosanoid biosynthetic process","termid":"GO:0046456"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0044281"],"is_obsolete":false,"name":"leukotriene biosynthetic process","secondary_identifiers":["Wikipedia:Leukotriene#Leukotriene_synthesis"],"synonyms":[{"name":"leukotriene anabolism","type":"exact"},{"name":"leukotriene biosynthesis","type":"exact"},{"name":"leukotriene formation","type":"exact"},{"name":"leukotriene synthesis","type":"exact"}],"termid":"GO:0019370"}


id: PBO:0027942
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_protein_localization_to_chromatin_at_RNA_polymerase_II-regulated_genes_during_vegetative_growth","termid":"PBO:0027942"}


id: FYPO:0003535
data:
  {"alleles_by_uniquename":{"SJAG_02392:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02392","name":"pom1delta","uniquename":"SJAG_02392:allele-1"}},"annotation_feature_type":"genotype","cv_annotations":{"single_locus_phenotype":[{"annotations":[121350],"is_not":false,"summary":null,"term":"FYPO:0003535"}]},"cv_name":"fission_yeast_phenotype","definition":"A cell population phenotype in which the bipolar index is lower than normal. The bipolar index is the proportion of the population undergoing bipolar growth at any given time.","definition_xrefs":["PMID:20501954","PomBase:mah","PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell population phenotype","termid":"FYPO:0000003"},{"relation_name":"is_a","term_name":"abnormal phenotype","termid":"FYPO:0001985"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02392":null},"genotype_count":1,"genotypes_by_uniquename":{"pom1delta":{"display_name":"pom1delta","display_uniquename":"pom1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02392:allele-1","expression":"Null"}]}]}},"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000003"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000003"],"is_obsolete":false,"name":"decreased bipolar index","references_by_uniquename":{"PMID:25866389":null},"single_locus_annotated_genes":["SJAG_02392"],"single_locus_genotype_uniquenames":["pom1delta"],"synonyms":[{"name":"decreased frequency of bipolar growth polarity","type":"related"},{"name":"decreased number of cells undergoing bipolar growth","type":"exact"},{"name":"reduced bipolar index","type":"exact"}],"termid":"FYPO:0003535","terms_by_termid":{"FYECO:0000162":null,"FYPO:0003535":null}}


id: GO:0110129
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. A histone deacetylase complex formed by the association of an HP1 protein with a SHREC complex. The SHREC2 complex is required for deacetylation of H3K14, and mediates transcriptional gene silencing by limiting RNA polymerase II access to heterochromatin. In fission yeast, the complex contains the SHREC subunits Clr1, Clr2, Clr3, and Mit1, and the HP1 protein Chp2.","definition_xrefs":["PMID:19111658","GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete SHREC2 complex (obsolete GO:0110129)","termid":"GO:0110129"}


id: MONDO:0021654
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"cutaneous mucinosis","termid":"MONDO:0002523"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"diffuse cutaneous mucinosis","secondary_identifiers":["MEDGEN:590581","SCTID:238945000","UMLS:C0406655","ICD9:701.8"],"termid":"MONDO:0021654","xrefs":{"Monarch":{"xref_id":"0021654"}}}


id: PBO:0038307
data:
  {"annotation_feature_type":"gene","cv_name":"gene_ex","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA_degradation","termid":"PBO:0038307"}


id: PBO:0054053
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1395","termid":"PBO:0054053"}


id: GO:0009323
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. An enzyme complex that catalyzes the transfer of an acetyl group to ribosomal-protein alanine, forming ribosomal-protein acetylalanine.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete ribosomal-protein-alanine N-acetyltransferase complex (obsolete GO:0009323)","termid":"GO:0009323"}


id: MONDO:0000858
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"colonic disorder","termid":"MONDO:0003409"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"neuronal intestinal dysplasia","secondary_identifiers":["MEDGEN:576840","UMLS:C0345244","ICD9:751.5","DOID:0080072","SCTID:253783001"],"termid":"MONDO:0000858","xrefs":{"Monarch":{"xref_id":"0000858"}}}


id: GO:0002010
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the molecular signal from the arterial baroreceptors is relayed to the vasomotor center causing it to signal increase arterial pressure.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nervous system process involved in regulation of systemic arterial blood pressure","termid":"GO:0001976"},{"relation_name":"part_of","term_name":"baroreceptor response to decreased systemic arterial blood pressure","termid":"GO:0001982"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"excitation of vasomotor center by baroreceptor signaling","synonyms":[{"name":"excitation of vasomotor center by baroreceptor signalling","type":"exact"}],"termid":"GO:0002010"}


id: PBO:0051627
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ILRUN pseudogene 1","termid":"PBO:0051627"}


id: PATO:0000938
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A structural quality inhering in a bearer by virtue of the bearer's exhibiting organisation.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"organization quality","termid":"PATO:0002264"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"organized","termid":"PATO:0000938"}


id: GO:0045500
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals initiated by an extracellular ligand binding to sevenless (sev; a receptor tyrosine kinase) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.","definition_xrefs":["GOC:bf","GOC:signaling","PMID:10771085"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell surface receptor protein tyrosine kinase signaling pathway","termid":"GO:0007169"},{"relation_name":"part_of","term_name":"R7 cell fate commitment","termid":"GO:0007465"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"sevenless signaling pathway","synonyms":[{"name":"sev receptor signaling pathway","type":"exact"},{"name":"sev signaling pathway","type":"exact"},{"name":"sevenless signalling pathway","type":"exact"}],"termid":"GO:0045500"}


id: GO:0009126
data:
  {"annotated_genes":["SJAG_01661","SJAG_03355","SJAG_01081","SJAG_01859","SJAG_06634","SJAG_02364","SJAG_01298","SJAG_04123","SJAG_04634","SJAG_01814","SJAG_02038","SJAG_02850","SJAG_03140","SJAG_01070","SJAG_04849","SJAG_00964","SJAG_04681","SJAG_00044"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[80706,78728],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0044208"},{"annotations":[66803,71662,78503,65440,73333,58353,60564,57215],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006189"},{"annotations":[59838,78141],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0046033"},{"annotations":[75680,57366],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0044209"},{"annotations":[59857,63912],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006177"},{"annotations":[65367],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0046037"},{"annotations":[77381,103014],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0032263"},{"annotations":[80707],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0046040"},{"annotations":[77382,65953],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0032264"},{"annotations":[77383,110114],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0032265"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.","definition_xrefs":["ISBN:0198506732","GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleoside monophosphate metabolic process","termid":"GO:0009123"}],"gene_count":18,"genes_by_uniquename":{"SJAG_00044":null,"SJAG_00964":null,"SJAG_01070":null,"SJAG_01081":null,"SJAG_01298":null,"SJAG_01661":null,"SJAG_01814":null,"SJAG_01859":null,"SJAG_02038":null,"SJAG_02364":null,"SJAG_02850":null,"SJAG_03140":null,"SJAG_03355":null,"SJAG_04123":null,"SJAG_04634":null,"SJAG_04681":null,"SJAG_04849":null,"SJAG_06634":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0044281","GO:0055086"],"is_obsolete":false,"name":"purine nucleoside monophosphate metabolic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000041":null,"GO_REF:0000104":null,"GO_REF:0000107":null,"GO_REF:0000108":null},"synonyms":[{"name":"purine nucleoside monophosphate metabolism","type":"exact"}],"termid":"GO:0009126","terms_by_termid":{"GO:0006177":null,"GO:0006189":null,"GO:0032263":null,"GO:0032264":null,"GO:0032265":null,"GO:0044208":null,"GO:0044209":null,"GO:0046033":null,"GO:0046037":null,"GO:0046040":null}}


id: PBO:0082806
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of U4/U6-U5 snRNP complex; involved in second catalytic step of splicing; participates in spliceosomal assembly through its interaction with U1 snRNA; largest and most evolutionarily conserved protein of the spliceosome; mutations in human ortholog, PRPF8, cause Retinitis pigmentosa and missplicing in Myelodysplastic syndrome; mouse ortholog interacts with androgen receptor and may have a role in prostate cancer","termid":"PBO:0082806"}


id: MONDO:0001609
data:
  {"annotated_genes":["SJAG_02330","SJAG_03684","SJAG_03089","SJAG_01798","SJAG_02453","SJAG_03889","SJAG_01759","SJAG_02208","SJAG_01732"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86802],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014118"},{"annotations":[87764],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011997"},{"annotations":[88024],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0957809"},{"annotations":[87884,87883],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0958017"},{"annotations":[88483],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0032899"},{"annotations":[88579],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011405"},{"annotations":[87488],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012559"},{"annotations":[88419],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010294"}]},"cv_name":"mondo","definition":"A decrease in the number of mature granulocytes (neutrophils, eosinophils, and basophils) in the peripheral blood.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"leukopenia","termid":"MONDO:0003785"}],"gene_count":9,"genes_by_uniquename":{"SJAG_01732":null,"SJAG_01759":null,"SJAG_01798":null,"SJAG_02208":null,"SJAG_02330":null,"SJAG_02453":null,"SJAG_03089":null,"SJAG_03684":null,"SJAG_03889":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0005046"],"is_obsolete":false,"name":"agranulocytosis","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["SCTID:417672002","ICD10WHO:D70","MEDGEN:7932","MESH:D000380","UMLS:C0001824","DOID:12987","ICD10CM:D70","icd11.foundation:1913706366","ICD9:288.8","NCIT:C2863"],"synonyms":[{"name":"Granulocytopenic disorder","type":"exact"},{"name":"Granulopenia","type":"exact"},{"name":"granulocytopenia","type":"exact"}],"termid":"MONDO:0001609","terms_by_termid":{"MONDO:0010294":null,"MONDO:0011405":null,"MONDO:0011997":null,"MONDO:0012559":null,"MONDO:0014118":null,"MONDO:0032899":null,"MONDO:0957809":null,"MONDO:0958017":null},"xrefs":{"Monarch":{"xref_id":"0001609"}}}


id: PBO:0113107
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dual-specificity S/T and tyrosine protein kinase; spindle position checkpoint component that works in parallel with Kin4p to prevent mitotic exit network (MEN) activation by the Cdc14 early anaphase release (FEAR) network; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent degradation of Rcn1p and Cdc6p, inhibition of protein kinase A, transcriptional regulation, inhibition of RNAPIII, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division","termid":"PBO:0113107"}


id: PBO:0036191
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_protein_transport_along_microtubule_to_cell_tip_during_vegetative_growth","termid":"PBO:0036191"}


id: GO:0048692
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in regeneration.","definition_xrefs":["GOC:lm","GOC:dph","GOC:jid","GOC:dgh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of axon extension","termid":"GO:0030517"},{"relation_name":"is_a","term_name":"negative regulation of sprouting of injured axon","termid":"GO:0048688"},{"relation_name":"is_a","term_name":"regulation of axon extension involved in regeneration","termid":"GO:0048690"},{"relation_name":"negatively_regulates","term_name":"axon extension involved in regeneration","termid":"GO:0048677"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of axon extension involved in regeneration","synonyms":[{"name":"down regulation of axon extension involved in regeneration","type":"exact"},{"name":"down-regulation of axon extension involved in regeneration","type":"exact"},{"name":"downregulation of axon extension involved in regeneration","type":"exact"},{"name":"inhibition of axon extension involved in regeneration","type":"narrow"}],"termid":"GO:0048692"}


id: GO:0002901
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any apoptotic process in a B cell that is mature, having left the bone marrow.","definition_xrefs":["GOC:mtg_apoptosis","ISBN:0781735149","CL:0000785","GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"B cell apoptotic process","termid":"GO:0001783"},{"relation_name":"part_of","term_name":"B cell homeostasis","termid":"GO:0001782"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mature B cell apoptotic process","synonyms":[{"name":"apoptosis of mature B cells","type":"exact"},{"name":"apoptosis of mature B lymphocytes","type":"exact"},{"name":"apoptosis of mature B-cells","type":"exact"},{"name":"apoptosis of mature B-lymphocytes","type":"exact"},{"name":"mature B cell apoptosis","type":"narrow"},{"name":"mature B cell programmed cell death by apoptosis","type":"exact"},{"name":"mature B lymphocyte apoptosis","type":"exact"},{"name":"mature B lymphocyte programmed cell death by apoptosis","type":"exact"},{"name":"mature B-cell apoptosis","type":"exact"},{"name":"mature B-cell programmed cell death by apoptosis","type":"exact"},{"name":"mature B-lymphocyte apoptosis","type":"exact"},{"name":"mature B-lymphocyte programmed cell death by apoptosis","type":"exact"},{"name":"programmed cell death of mature B cells by apoptosis","type":"exact"},{"name":"programmed cell death of mature B lymphocytes by apoptosis","type":"exact"},{"name":"programmed cell death of mature B-cells by apoptosis","type":"exact"},{"name":"programmed cell death of mature B-lymphocytes by apoptosis","type":"exact"},{"name":"programmed cell death, mature B cells","type":"exact"},{"name":"programmed cell death, mature B lymphocytes","type":"exact"},{"name":"programmed cell death, mature B-cells","type":"exact"},{"name":"programmed cell death, mature B-lymphocytes","type":"exact"}],"termid":"GO:0002901"}


id: MONDO:0001505
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Acute hepatitis resulting from ingestion of alcohol.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hepatitis","termid":"MONDO:0002251"},{"relation_name":"is_a","term_name":"alcoholic liver diseases","termid":"MONDO:0043693"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0002515"}],"interesting_parent_ids":["MONDO:0002515","MONDO:0004335"],"is_obsolete":false,"name":"alcoholic hepatitis","secondary_identifiers":["UMLS:C0019187","MEDGEN:42422","icd11.foundation:229221394","DOID:12351","EFO:1001345","CSP:1754-6978","ICD10CM:K70.1","ICD9:571.1","NCIT:C34684","SCTID:235875008","MESH:D006519"],"synonyms":[{"name":"acute alcoholic Hepatitis","type":"exact"},{"name":"acute alcoholic hepatitis","type":"exact"},{"name":"acute alcoholic liver disease","type":"exact"},{"name":"alcoholic Hepatitis","type":"exact"},{"name":"alcoholic hepatitis","type":"exact"}],"termid":"MONDO:0001505","xrefs":{"Monarch":{"xref_id":"0001505"}}}


id: PBO:0085680
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein involved in prospore membrane morphogenesis; peripheral membrane protein that localizes to the prospore membrane and at numerous membrane contact sites; involved in sporulation, vacuolar protein sorting, prospore membrane formation during sporulation, and protein-Golgi retention; required for mitochondrial integrity; contains a PH-like domain; homologous to human CHAC and COH1 which are involved in Chorea-acanthocytosis and Cohen syndrome, respectively","termid":"PBO:0085680"}


id: MONDO:1011307
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Chromosomal disorder that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"non-human animal disease","termid":"MONDO:0005583"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosomal disorder, non-human animal","termid":"MONDO:1011307","xrefs":{"Monarch":{"xref_id":"1011307"}}}


id: GO:0050807
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).","definition_xrefs":["GOC:tb","GOC:ai","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cellular component organization","termid":"GO:0051128"},{"relation_name":"part_of","term_name":"regulation of synapse structure or activity","termid":"GO:0050803"},{"relation_name":"regulates","term_name":"synapse organization","termid":"GO:0050808"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of synapse organization","synonyms":[{"name":"regulation of synapse organisation","type":"exact"},{"name":"regulation of synapse organization and biogenesis","type":"related"},{"name":"regulation of synapse structure","type":"exact"}],"termid":"GO:0050807"}


id: PBO:0040670
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BCAN antisense RNA 2","termid":"PBO:0040670"}


id: PBO:0072160
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S15a pseudogene 37","termid":"PBO:0072160"}


id: RO:0002107
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"A relation between a motor neuron and a muscle that it synapses to via a type II bouton.","direct_ancestors":[{"relation_name":"is_a","term_name":"synapsed_to","termid":"RO:0002120"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"synapsed_via_type_II_bouton_to","termid":"RO:0002107"}


id: PBO:0060289
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myosin light chain 6","termid":"PBO:0060289"}


id: PBO:0077479
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein 200B","termid":"PBO:0077479"}


id: FYPO:0007456
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of 3' overhang single-stranded DNA endodeoxyribonuclease activity is increased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased catalytic activity","termid":"FYPO:0000662"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000707","FYPO:0000661","FYPO:0000654","FYPO:0000652"],"is_obsolete":false,"name":"increased 3' overhang single-stranded DNA endodeoxyribonuclease activity","termid":"FYPO:0007456"}


id: PBO:0000061
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pseudogene","termid":"PBO:0000061"}


id: PBO:0071320
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L27a pseudogene 4","termid":"PBO:0071320"}


id: MONDO:0016594
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Superficial siderosis is a rare neurologic disease characterized by progressive sensorineural hearing loss, cerebellar ataxia, pyramidal signs, and neuroimaging findings revealing hemosiderin deposits in the spinal and cranial leptomeninges and subpial layer. The disease progresses slowly and patients may present with mild cognitive impairment, nystagmus, dysmetria, spasticity, dysdiadochokinesia, dysarthria, hyperreflexia, and Babinski signs. Additional features reported include dementia, urinary incontinence, anosmia, ageusia, and anisocoria.","definition_xrefs":["Orphanet:247245"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"acquired ataxia","termid":"MONDO:0016593"},{"relation_name":"is_a","term_name":"neurodegenerative disease","termid":"MONDO:0005559"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"superficial siderosis","secondary_identifiers":["NANDO:1200543","UMLS:C2938918","MEDGEN:1371500","GARD:9484"],"synonyms":[{"name":"hemosiderosis of the central nervous system","type":"exact"},{"name":"superficial hemosiderosis of the CNS","type":"exact"},{"name":"superficial hemosiderosis of the central nervous system","type":"exact"},{"name":"superficial siderosis of the CNS","type":"exact"},{"name":"superficial siderosis of the central nervous system","type":"exact"}],"termid":"MONDO:0016594","xrefs":{"Monarch":{"xref_id":"0016594"}}}


id: PBO:0085767
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein kinase primarily involved in telomere length regulation; contributes to cell cycle checkpoint control in response to DNA damage; acts with Red1p and Mec1p to promote interhomolog recombination by phosphorylation of Hop1; functionally redundant with Mec1p; regulates P-body formation induced by replication stress; homolog of human ataxia-telangiectasia mutated (ATM) gene","termid":"PBO:0085767"}


id: PBO:0003855
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial manganese ion transporter (predicted)","termid":"PBO:0003855"}


id: PBO:0086700
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative protein of unknown function; located adjacent to ARS503 and the telomere on the left arm of chromosome V; regulated by inositol/choline","termid":"PBO:0086700"}


id: PBO:0082688
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of the GARP (Golgi-associated retrograde protein) complex; GARP is required for the recycling of proteins from endosomes to the late Golgi, and for mitosis after DNA damage induced checkpoint arrest; required for vacuolar protein sorting; members of the GARP complex are Vps51p-Vps52p-Vps53p-Vps54p; human ortholog is implicated in progressive cerebello-cerebral atrophy type 2 (PCCA2)","termid":"PBO:0082688"}


id: PBO:0113381
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative lipid transport protein; peripheral membrane protein required for vesicle formation during autophagy, pexophagy and the CVT pathway; directed to autophagic membranes by Atg18p where it acts as a PAS-ER membrane tether during autophagosome formation; involved in Atg9p cycling between the PAS and mitochondria; binds the phospholipid PI(3)P via an APT1 domain; essential for cell cycle progression from G2/M to G1 under nitrogen starvation; forms cytoplasmic foci upon DNA replication stress","termid":"PBO:0113381"}


id: FYPO:0006221
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the site of cell division is decreased, and some of the protein is present in the cytoplasm instead.","definition_xrefs":["PMID:26132084","PomBase:mah"],"direct_ancestors":[{"relation_name":"has_part","term_name":"protein mislocalized to cytoplasm during vegetative growth","termid":"FYPO:0000783"},{"relation_name":"is_a","term_name":"protein mislocalized to cytoplasm during vegetative growth","termid":"FYPO:0000783"},{"relation_name":"is_a","term_name":"decreased protein localization to cell division site","termid":"FYPO:0002869"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"has_part","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0000138"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001985","FYPO:0000138","FYPO:0001320","FYPO:0005447"],"is_obsolete":false,"name":"decreased protein localization to cell division site, with protein mislocalized to cytoplasm","synonyms":[{"name":"decreased protein localisation to cell division site, with protein mislocalised to cytoplasm","type":"exact"},{"name":"decreased protein localization to cell division site, with protein mislocalized to cytoplasm, during mitotic cell cycle","type":"related"},{"name":"decreased protein localization to cell division site, with protein mislocalized to cytoplasm, during vegetative growth","type":"exact"},{"name":"decreased protein recruitment to cell division site, with protein mislocalized to cytoplasm","type":"related"},{"name":"reduced protein localization to cell division site, with protein mislocalized to cytoplasm","type":"exact"}],"termid":"FYPO:0006221"}


id: GO:0047503
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (-)-borneol + NAD+ = (1S,4S)-camphor + H+ + NADH.","definition_xrefs":["RHEA:22128","EC:1.1.1.227"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"(-)-borneol dehydrogenase activity","secondary_identifiers":["KEGG_REACTION:R02945","MetaCyc:--BORNEOL-DEHYDROGENASE-RXN"],"synonyms":[{"name":"(-)-borneol:NAD+ oxidoreductase activity","type":"related"}],"termid":"GO:0047503"}


id: MONDO:0005055
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A malignant neoplasm characterized by a vascular proliferation which usually contains blunt endothelial cells. Erythrocyte extravasation and hemosiderin deposition are frequently present. The most frequent site of involvement is the skin; however it may also occur internally. It generally develops in people with compromised immune systems including those with acquired immune deficiency syndrome (AIDS).","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete connective tissue cancer (obsolete MONDO:0002176)","termid":"MONDO:0002176"},{"relation_name":"is_a","term_name":"viral infectious disease","termid":"MONDO:0005108"},{"relation_name":"is_a","term_name":"human herpesvirus 8-related tumor","termid":"MONDO:0015157"},{"relation_name":"is_a","term_name":"angiosarcoma","termid":"MONDO:0016982"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"Kaposi's sarcoma","secondary_identifiers":["ICDO:9140/3","EFO:0000558","Orphanet:33276","ICD9:176.8","ICD9:176.9","MEDGEN:11321","HP:0100726","UMLS:C0036220","MESH:D012514","MedDRA:10023284","DOID:8632","ICD10CM:C46","ICD9:176","GARD:6814","NCIT:C9087","SCTID:109385007"],"synonyms":[{"name":"African lymphadenopathic Kaposi's sarcoma","type":"related"},{"name":"HHV8","type":"related"},{"name":"KS","type":"exact"},{"name":"KSHV","type":"related"},{"name":"Kaposi sarcoma","type":"exact"},{"name":"Kaposi sarcoma herpesvirus","type":"related"},{"name":"Kaposi's sarcoma","type":"exact"},{"name":"Kaposi's sarcoma (disease)","type":"exact"},{"name":"Kaposi's sarcoma of anus","type":"narrow"},{"name":"Kaposi's sarcoma of central nervous system","type":"narrow"},{"name":"Kaposi's sarcoma of conjunctiva","type":"exact"},{"name":"Kaposi's sarcoma of cornea","type":"exact"},{"name":"Kaposi's sarcoma of esophagus","type":"narrow"},{"name":"Kaposi's sarcoma of gastrointestinal sites","type":"narrow"},{"name":"Kaposi's sarcoma of heart","type":"narrow"},{"name":"Kaposi's sarcoma of lung","type":"exact"},{"name":"Kaposi's sarcoma of lymph nodes","type":"narrow"},{"name":"Kaposi's sarcoma of oesophagus","type":"narrow"},{"name":"Kaposi's sarcoma of palate","type":"exact"},{"name":"Kaposi's sarcoma of penis","type":"narrow"},{"name":"Kaposi's sarcoma of skin","type":"narrow"},{"name":"Kaposi's sarcoma of soft tissue","type":"exact"},{"name":"Kaposi's sarcoma of soft tissues","type":"exact"},{"name":"Kaposi's sarcoma of the CNS","type":"narrow"},{"name":"Kaposi's sarcoma of the gallbladder","type":"narrow"},{"name":"Kaposi's sarcoma of the prostate","type":"narrow"},{"name":"Kaposi's sarcoma, lung","type":"narrow"},{"name":"Kaposi's sarcoma, skin","type":"narrow"},{"name":"Kaposi's sarcoma-associated herpesvirus (KSHV)","type":"related"},{"name":"Mediterranean Kaposi sarcoma","type":"related"},{"name":"anal Kaposi's sarcoma","type":"narrow"},{"name":"cardiac Kaposi's sarcoma","type":"narrow"},{"name":"central nervous system Kaposi's sarcoma","type":"narrow"},{"name":"conjunctival Kaposi's sarcoma","type":"narrow"},{"name":"corneal Kaposi's sarcoma","type":"narrow"},{"name":"cutaneous Kaposi's sarcoma","type":"narrow"},{"name":"esophageal Kaposi's sarcoma","type":"narrow"},{"name":"gallbladder Kaposi's sarcoma","type":"narrow"},{"name":"gastric Kaposi's sarcoma","type":"narrow"},{"name":"human herpesvirus 8","type":"related"},{"name":"intestinal Kaposi's sarcoma","type":"narrow"},{"name":"lymph node Kaposi's sarcoma","type":"narrow"},{"name":"lymphadenopathic Kaposi's sarcoma","type":"narrow"},{"name":"multiple hemorrhagic sarcoma","type":"narrow"},{"name":"non AIDS related Kaposi sarcoma","type":"related"},{"name":"palate Kaposi's sarcoma","type":"narrow"},{"name":"penis Kaposi's sarcoma","type":"narrow"},{"name":"prostate Kaposi's sarcoma","type":"narrow"},{"name":"pulmonary Kaposi's sarcoma","type":"narrow"},{"name":"soft tissue Kaposi's sarcoma","type":"narrow"}],"termid":"MONDO:0005055","xrefs":{"Monarch":{"xref_id":"0005055"}}}


id: PBO:0109123
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Gfo/Idh/MocA-like oxidoreductase domain containing 3, pseudogene","termid":"PBO:0109123"}


id: PBO:0078292
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Cys (anticodon GCA) 25-1","termid":"PBO:0078292"}


id: FYPO:0005117
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which transcription occurs to is normal (i.e. indistinguishable from wild type) in extent, timing, start or termination site, etc. when the cell is subject to nitrogen starvation. All genes, or a specific subset of genes, may be measured.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal transcription","termid":"FYPO:0002882"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000294"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000257","FYPO:0000294"],"is_obsolete":false,"name":"normal transcription during nitrogen starvation","synonyms":[{"name":"normal transcription during cellular response to nitrogen starvation","type":"exact"},{"name":"normal transcription during nitrogen depletion","type":"exact"},{"name":"normal transcription during nitrogen deprivation","type":"exact"},{"name":"normal transcription during nitrogen limitation","type":"exact"},{"name":"normal transcription in response to nitrogen starvation","type":"exact"}],"termid":"FYPO:0005117"}


id: PBO:0005245
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial ribosomal protein subunit L2 (predicted)","termid":"PBO:0005245"}


id: PBO:0080682
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WAS/WASL interacting protein family member 2","termid":"PBO:0080682"}


id: GO:0043422
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to protein kinase B, an intracellular kinase that is important in regulating glucose metabolism.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein kinase binding","termid":"GO:0019901"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0005515"}],"interesting_parent_ids":["GO:0005515","GO:0005488","GO:0003674"],"is_obsolete":false,"name":"protein kinase B binding","synonyms":[{"name":"Akt binding","type":"exact"},{"name":"PKB binding","type":"exact"}],"termid":"GO:0043422"}


id: PBO:0047139
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 174 member B","termid":"PBO:0047139"}


id: PBO:0060920
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"neurofibromin 1 pseudogene 7","termid":"PBO:0060920"}


id: MONDO:0009798
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare, genetic intellectual disability syndrome characterized by macrocephaly, hypotonia, dysmorphic facial features (wide forehead, ptosis, downslanting palpebral fissures, enlarged and calcified external ears, large jaw), sparse body hair, tall stature, and intellectual disability. Hearing loss, insulin-resistant diabetes, and progressive distal muscle wasting (leading to joint contractures) have also been reported in adulthood. Rare manifestations include behavioral abnormalities (aggression and restlessness), hypothyroidism, cerebral calcification, ataxia, and peripheral neuropathy.","definition_xrefs":["Orphanet:3042"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Primrose syndrome","secondary_identifiers":["UMLS:C0796121","GARD:4488","MESH:C536420","SCTID:726709001","OMIM:259050","MEDGEN:162911"],"synonyms":[{"name":"PRIMS","type":"related"},{"name":"Primrose syndrome","type":"exact"},{"name":"intellectual disability-cataracts-calcified pinnae-myopathy syndrome","type":"exact"},{"name":"ossified EAR cartilages with mental deficiency, muscle wasting, and BONY changes","type":"related"}],"termid":"MONDO:0009798","xrefs":{"Monarch":{"xref_id":"0009798"}}}


id: FYPO:0003233
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 at heterochromatin islands is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal histone H3-K9 methylation during vegetative growth","termid":"FYPO:0003232"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001312","FYPO:0001320","FYPO:0000257","FYPO:0000002"],"is_obsolete":false,"name":"normal histone H3-K9 methylation at heterochromatin island during vegetative growth","synonyms":[{"name":"normal histone H3 K9 methylation at heterochromatin island during vegetative growth","type":"exact"},{"name":"normal histone H3-K9 methylation at heterochromatin island during mitotic cell cycle","type":"related"},{"name":"normal histone H3K9me at heterochromatin island during vegetative growth","type":"exact"},{"name":"normal histone lysine H3 K9 methylation at heterochromatin island during vegetative growth","type":"exact"}],"termid":"FYPO:0003233"}


id: GO:0006662
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol.","definition_xrefs":["GOC:ai","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ether metabolic process","termid":"GO:0018904"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0008150"],"is_obsolete":false,"name":"glycerol ether metabolic process","synonyms":[{"name":"glycerol ether metabolism","type":"exact"}],"termid":"GO:0006662"}


id: PBO:0057411
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 548m","termid":"PBO:0057411"}


id: PBO:0044286
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome X open reading frame 49B","termid":"PBO:0044286"}


id: MONDO:0016183
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete qualitative or quantitative defects of protein glycosyltransferase-like (obsolete MONDO:0016183)","secondary_identifiers":["Orphanet:209027"],"termid":"MONDO:0016183","xrefs":{"Monarch":{"xref_id":"0016183"}}}


id: FYPO:0007185
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which progression through the mitotic cell cycle is abnormally arrested at the mitotic G2/M phase transition during a cellular response to hydroxyurea.","definition_xrefs":["PMID:28377506","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal cell cycle arrest at mitotic G2/M phase transition","termid":"FYPO:0000400"},{"relation_name":"is_a","term_name":"abnormal mitotic cell cycle regulation during cellular response to hydroxyurea","termid":"FYPO:0001933"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000298"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000631"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000002","FYPO:0000298","FYPO:0005447","FYPO:0000631","FYPO:0001985"],"is_obsolete":false,"name":"abnormal cell cycle arrest at mitotic G2/M phase transition during cellular response to hydroxyurea","synonyms":[{"name":"abnormal cell cycle arrest at mitotic G2/M phase transition during cellular response to HU","type":"exact"},{"name":"abnormal cell cycle arrest in mitotic G2 phase during cellular response to hydroxyurea","type":"related"},{"name":"abnormal mitotic cell cycle arrest at mitotic G2/M phase transition during cellular response to hydroxyurea","type":"exact"},{"name":"abolished mitotic G2/M phase transition during cellular response to hydroxyurea","type":"related"},{"name":"cell cycle arrest at mitotic G2/M phase transition during cellular response to hydroxyurea","type":"exact"},{"name":"mitotic G2 phase arrest during cellular response to hydroxyurea","type":"exact"}],"termid":"FYPO:0007185"}


id: MONDO:0014145
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any Leber congenital amaurosis in which the cause of the disease is a mutation in the GDF6 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Leber congenital amaurosis","termid":"MONDO:0018998"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"},{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328","MONDO:0002320"],"is_obsolete":false,"name":"Leber congenital amaurosis 17","secondary_identifiers":["MEDGEN:811616","OMIM:615360","UMLS:C3715164","GARD:15950","DOID:0110217","ICD10CM:H35.5"],"synonyms":[{"name":"GDF6 Leber congenital amaurosis","type":"exact"},{"name":"LCA17","type":"exact"},{"name":"Leber congenital amaurosis 17","type":"exact"},{"name":"Leber congenital amaurosis caused by mutation in GDF6","type":"exact"},{"name":"Leber congenital amaurosis type 17","type":"exact"}],"termid":"MONDO:0014145","xrefs":{"Monarch":{"xref_id":"0014145"}}}


id: PBO:0065719
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Prader Willi/Angelman region RNA 5","termid":"PBO:0065719"}


id: MONDO:0018774
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete erythrokeratodermia-cardiomyopathy syndrome (obsolete MONDO:0018774)","secondary_identifiers":["GARD:21950"],"termid":"MONDO:0018774","xrefs":{"Monarch":{"xref_id":"0018774"}}}


id: GO:2000489
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of hepatic stellate cell activation.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cell activation","termid":"GO:0050865"},{"relation_name":"regulates","term_name":"hepatic stellate cell activation","termid":"GO:0035733"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of hepatic stellate cell activation","termid":"GO:2000489"}


id: PBO:0117253
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TORC1 inhibitor, Ecl3","termid":"PBO:0117253"}


id: GO:0014876
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a injury. This process occurs as part of the regulation of muscle adaptation.","definition_xrefs":["GOC:ef","GOC:mtg_muscle"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to wounding","termid":"GO:0009611"},{"relation_name":"is_a","term_name":"response to stimulus involved in regulation of muscle adaptation","termid":"GO:0014874"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to injury involved in regulation of muscle adaptation","synonyms":[{"name":"response to injury involved in regulation of muscle plasticity","type":"related"}],"termid":"GO:0014876"}


id: PBO:0027153
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_vacuolar_histidine_level","termid":"PBO:0027153"}


id: GO:0075283
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of a multicellular or syncytial spore via septations over time, from its initiation to the mature structure.","definition_xrefs":["GOC:pamgo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sporulation","termid":"GO:0043934"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"sporulation resulting in formation of a multicellular or syncytial spore","synonyms":[{"name":"multicellular or syncytial spore formation by sporulation","type":"exact"}],"termid":"GO:0075283"}


id: GO:0001848
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a component or product of the complement cascade.","definition_xrefs":["GOC:add","ISBN:0781735149"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein binding","termid":"GO:0005515"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0005488","GO:0005515","GO:0003674"],"is_obsolete":false,"name":"complement binding","termid":"GO:0001848"}


id: GO:1902749
data:
  {"annotated_genes":["SJAG_00214","SJAG_01118","SJAG_03160","SJAG_03602","SJAG_03073","SJAG_02266","SJAG_00600","SJAG_02074","SJAG_03942","SJAG_02858","SJAG_05373","SJAG_01010","SJAG_00318","SJAG_00082","SJAG_03126","SJAG_01076","SJAG_01205","SJAG_03026","SJAG_01901","SJAG_00216","SJAG_02563","SJAG_00256","SJAG_02332","SJAG_01805","SJAG_01837","SJAG_01146","SJAG_01429","SJAG_04671","SJAG_03695","SJAG_00364","SJAG_02342","SJAG_00883","SJAG_03486","SJAG_01855","SJAG_01456","SJAG_04140","SJAG_04394","SJAG_01044","SJAG_00640","SJAG_04287","SJAG_01084","SJAG_03854","SJAG_01873","SJAG_02576","SJAG_06592","SJAG_00526","SJAG_03927","SJAG_04597","SJAG_01000","SJAG_04486","SJAG_00117","SJAG_02098","SJAG_02771","SJAG_02723","SJAG_04332","SJAG_04280","SJAG_01680","SJAG_02392","SJAG_03309","SJAG_01605","SJAG_02592","SJAG_03592","SJAG_03067"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[117919,93243,108449],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033315"},{"annotations":[96221,103261,117865,91811,102357],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0044878"},{"annotations":[101172,76642,80677,95776,117921,93244,81268,108452,119142,72857,101005,74071,111162,113890,118665,118970,102358],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033314"},{"annotations":[100242,96354,117867,97666],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031569"},{"annotations":[93245,108453,62364,81141,101174,61540,118883,113584,60831,74073,67830,76994,102872,90935,111163],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0007095"},{"annotations":[116330,114336,108484,108847,80335,96180,102818,58822,95030,113672,60729,95374,106324,113290],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010972"},{"annotations":[72427,80337],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0110031"},{"annotations":[95615,75217,112192,96223,89862,100243,110414,96184,109068,118536,72475,103578,89871,100815,93952,118347,105310,113055,93552],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010971"},{"annotations":[103211,89666],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905287"},{"annotations":[75219],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0110032"},{"annotations":[113821],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010389"}]},"cv_name":"biological_process","definition":"Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle.","definition_xrefs":["GO_REF:0000058","GOC:jl","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cell cycle phase transition","termid":"GO:1901987"},{"relation_name":"regulates","term_name":"cell cycle G2/M phase transition","termid":"GO:0044839"}],"gene_count":63,"genes_by_uniquename":{"SJAG_00082":null,"SJAG_00117":null,"SJAG_00214":null,"SJAG_00216":null,"SJAG_00256":null,"SJAG_00318":null,"SJAG_00364":null,"SJAG_00526":null,"SJAG_00600":null,"SJAG_00640":null,"SJAG_00883":null,"SJAG_01000":null,"SJAG_01010":null,"SJAG_01044":null,"SJAG_01076":null,"SJAG_01084":null,"SJAG_01118":null,"SJAG_01146":null,"SJAG_01205":null,"SJAG_01429":null,"SJAG_01456":null,"SJAG_01605":null,"SJAG_01680":null,"SJAG_01805":null,"SJAG_01837":null,"SJAG_01855":null,"SJAG_01873":null,"SJAG_01901":null,"SJAG_02074":null,"SJAG_02098":null,"SJAG_02266":null,"SJAG_02332":null,"SJAG_02342":null,"SJAG_02392":null,"SJAG_02563":null,"SJAG_02576":null,"SJAG_02592":null,"SJAG_02723":null,"SJAG_02771":null,"SJAG_02858":null,"SJAG_03026":null,"SJAG_03067":null,"SJAG_03073":null,"SJAG_03126":null,"SJAG_03160":null,"SJAG_03309":null,"SJAG_03486":null,"SJAG_03592":null,"SJAG_03602":null,"SJAG_03695":null,"SJAG_03854":null,"SJAG_03927":null,"SJAG_03942":null,"SJAG_04140":null,"SJAG_04280":null,"SJAG_04287":null,"SJAG_04332":null,"SJAG_04394":null,"SJAG_04486":null,"SJAG_04597":null,"SJAG_04671":null,"SJAG_05373":null,"SJAG_06592":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0007049"],"is_obsolete":false,"name":"regulation of cell cycle G2/M phase transition","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null,"GO_REF:0000117":null},"secondary_identifiers":["Reactome:R-HSA-8852276"],"termid":"GO:1902749","terms_by_termid":{"GO:0007095":null,"GO:0010389":null,"GO:0010971":null,"GO:0010972":null,"GO:0031569":null,"GO:0033314":null,"GO:0033315":null,"GO:0044878":null,"GO:0110031":null,"GO:0110032":null,"GO:1905287":null}}


id: PBO:0081331
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 132","termid":"PBO:0081331"}


id: PBO:0060422
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NAALADL2 antisense RNA 1","termid":"PBO:0060422"}


id: PBO:0046378
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"endosomal transmembrane epsin interactor 2","termid":"PBO:0046378"}


id: PBO:0064671
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peptidylprolyl isomerase A pseudogene 6","termid":"PBO:0064671"}


id: PBO:0027805
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_JM216","termid":"PBO:0027805"}


id: PBO:0039098
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"adenosylhomocysteinase pseudogene 2","termid":"PBO:0039098"}


id: GO:0007516
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the hemocyte over time, from its formation to the mature structure. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.","definition_xrefs":["GOC:bf","GOC:mtg_sensu"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hemopoiesis","termid":"GO:0030097"},{"relation_name":"part_of","term_name":"hemocyte differentiation","termid":"GO:0042386"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"hemocyte development","synonyms":[{"name":"arthropod blood cell development","type":"exact"}],"termid":"GO:0007516"}


id: PBO:0063333
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2","termid":"PBO:0063333"}


id: PBO:0039800
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"amphiregulin","termid":"PBO:0039800"}


id: GO:0016438
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: GDP-alpha-D-mannose + queuosine34 in tRNA(Asp) = GDP + H+ + O-4''-alpha-D-mannosylqueuosine34 in tRNA(Asp).","definition_xrefs":["RHEA:12885"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mannosyltransferase activity","termid":"GO:0000030"},{"relation_name":"is_a","term_name":"catalytic activity, acting on a tRNA","termid":"GO:0140101"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0140101"},{"rel_name":"is_a","termid":"GO:0016757"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0016740","GO:0003824","GO:0140098","GO:0140101","GO:0016757","GO:0003674"],"is_obsolete":false,"name":"tRNA-queuosine(34) beta-mannosyltransferase activity","secondary_identifiers":["MetaCyc:2.4.1.110-RXN","EC:2.4.1.110"],"synonyms":[{"name":"GDP-mannose:tRNAAsp-queuosine O-5''-beta-D-mannosyltransferase activity","type":"related"},{"name":"tRNA-queuosine beta-mannosyltransferase activity","type":"broad"}],"termid":"GO:0016438"}


id: GO:0008521
data:
  {"annotated_genes":["SJAG_04325"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[59996],"is_not":false,"summary":null,"term":"GO:0008521"}]},"cv_name":"molecular_function","definition":"Enables the transfer of acetyl-CoA from one side of a membrane to the other. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"organic anion transmembrane transporter activity","termid":"GO:0008514"},{"relation_name":"is_a","term_name":"organophosphate ester transmembrane transporter activity","termid":"GO:0015605"},{"relation_name":"is_a","term_name":"nucleobase-containing compound transmembrane transporter activity","termid":"GO:0015932"},{"relation_name":"is_a","term_name":"amide transmembrane transporter activity","termid":"GO:0042887"},{"relation_name":"is_a","term_name":"sulfur compound transmembrane transporter activity","termid":"GO:1901682"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04325":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005215","GO:0022857"],"is_obsolete":false,"name":"acetyl-CoA transmembrane transporter activity","references_by_uniquename":{"GO_REF:0000002":null},"secondary_identifiers":["Reactome:R-HSA-727759","Reactome:R-HSA-5649742"],"synonyms":[{"name":"acetyl-CoA transporter activity","type":"related"}],"termid":"GO:0008521","terms_by_termid":{"GO:0008521":null}}


id: PBO:0070094
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U7 small nuclear 8 pseudogene","termid":"PBO:0070094"}


id: PBO:0046948
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 74 member A1","termid":"PBO:0046948"}


id: MONDO:0018675
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A IgG4-related disease that involves the eye.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"eye disorder","termid":"MONDO:0005328"},{"relation_name":"is_a","term_name":"immunoglobulin G4-related sclerosing disease","termid":"MONDO:0017287"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005328"],"is_obsolete":false,"name":"IgG4-related ophthalmic disorder","secondary_identifiers":["MEDGEN:1800432","UMLS:C5569009","Orphanet:449563","GARD:21885"],"synonyms":[{"name":"IgG4-related disease of eye","type":"exact"},{"name":"eye IgG4-related disease","type":"exact"}],"termid":"MONDO:0018675","xrefs":{"Monarch":{"xref_id":"0018675"}}}


id: GO:2000524
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of T cell costimulation.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of immune system process","termid":"GO:0002683"},{"relation_name":"is_a","term_name":"regulation of T cell costimulation","termid":"GO:2000523"},{"relation_name":"negatively_regulates","term_name":"T cell costimulation","termid":"GO:0031295"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0007155"}],"interesting_parent_ids":["GO:0007155","GO:0008150"],"is_obsolete":false,"name":"negative regulation of T cell costimulation","synonyms":[{"name":"negative regulation of T cell co-stimulation","type":"exact"},{"name":"negative regulation of T lymphocyte costimulation","type":"exact"},{"name":"negative regulation of T-cell co-stimulation","type":"exact"},{"name":"negative regulation of T-cell costimulation","type":"exact"},{"name":"negative regulation of T-lymphocyte costimulation","type":"exact"}],"termid":"GO:2000524"}


id: MONDO:0005364
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Graves' disease is an autoimmune disorder that leads to overactivity of the thyroid gland (hyperthyroidism).It is caused by an abnormal immune system response that causes the thyroid gland to produce too much thyroid hormones. Graves disease is the most common cause of hyperthyroidism andoccurs mostoften in women over age 20. However, the disorder may occur at any age and may affect males as well.Treatmentmayinclude radioiodine therapy, antithyroid drugs, and/or thyroid surgery.","definition_xrefs":["GARD:0006549"],"direct_ancestors":[{"relation_name":"is_a","term_name":"toxic diffuse goiter","termid":"MONDO:0001104"},{"relation_name":"is_a","term_name":"autoimmune thyroid disease","termid":"MONDO:0005623"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"Graves disease","secondary_identifiers":["MEDGEN:6677","NANDO:2200328","UMLS:C0018213","MESH:D006111","SCTID:353295004","NCIT:C3071","EFO:0004237","DOID:12361","ICD9:242.0"],"synonyms":[{"name":"Basedow disease","type":"related"},{"name":"Basedow's disease","type":"related"},{"name":"Graves disease","type":"exact"},{"name":"Graves' disease","type":"related"},{"name":"Graves' hyperthyroidism","type":"related"},{"name":"exophthalmic goiter","type":"exact"},{"name":"exophthalmic goitre","type":"exact"},{"name":"grave's disease","type":"exact"},{"name":"parry disease","type":"related"}],"termid":"MONDO:0005364","xrefs":{"Monarch":{"xref_id":"0005364"}}}


id: GO:0046192
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anaerobic phenol-containing compound metabolic process","termid":"GO:0042215"},{"relation_name":"is_a","term_name":"phenol-containing compound biosynthetic process","termid":"GO:0046189"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"anaerobic phenol-containing compound biosynthetic process","synonyms":[{"name":"anaerobic phenol-containing compound anabolism","type":"exact"},{"name":"anaerobic phenol-containing compound biosynthesis","type":"exact"},{"name":"anaerobic phenol-containing compound formation","type":"exact"},{"name":"anaerobic phenol-containing compound synthesis","type":"exact"}],"termid":"GO:0046192"}


id: MONDO:0014815
data:
  {"annotated_genes":["SJAG_01991"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87600],"is_not":false,"summary":null,"term":"MONDO:0014815"}]},"cv_name":"mondo","definition":"Any autosomal recessive non-syndromic intellectual disability in which the cause of the disease is a mutation in the LMAN2L gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive non-syndromic intellectual disability","termid":"MONDO:0019502"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01991":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0037792"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0006025","MONDO:0037792"],"is_obsolete":false,"name":"intellectual disability, autosomal recessive 52","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["DOID:0081215","MEDGEN:903181","GARD:22572","OMIM:616887","UMLS:C4225168"],"synonyms":[{"name":"LMAN2L autosomal recessive non-syndromic intellectual disability","type":"exact"},{"name":"MRT52","type":"exact"},{"name":"autosomal recessive non-syndromic intellectual disability caused by mutation in LMAN2L","type":"exact"},{"name":"intellectual developmental disorder, autosomal recessive 52","type":"exact"},{"name":"intellectual disability, autosomal recessive 52","type":"exact"},{"name":"intellectual disability, autosomal recessive type 52","type":"exact"},{"name":"mental retardation, autosomal recessive 52","type":"exact"},{"name":"mental retardation, autosomal recessive type 52","type":"exact"}],"termid":"MONDO:0014815","terms_by_termid":{"MONDO:0014815":null},"xrefs":{"Monarch":{"xref_id":"0014815"}}}


id: PBO:0039656
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"adaptor related protein complex 1 subunit sigma 3","termid":"PBO:0039656"}


id: GO:0032276
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the regulated release of a gonadotropin.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of endocrine process","termid":"GO:0044060"},{"relation_name":"is_a","term_name":"regulation of hormone secretion","termid":"GO:0046883"},{"relation_name":"regulates","term_name":"gonadotropin secretion","termid":"GO:0032274"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0023052","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"regulation of gonadotropin secretion","synonyms":[{"name":"regulation of gonadotrophin secretion","type":"exact"}],"termid":"GO:0032276"}


id: PBO:0028276
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_protein_localization_to_septum","termid":"PBO:0028276"}


id: SO:0002383
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A variant that has been found to be pathogenic in the context of a neoplastic disease.","definition_xrefs":["PMID:35101336"],"direct_ancestors":[{"relation_name":"is_a","term_name":"disease_associated_variant","termid":"SO:0001771"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"oncogenic_variant","termid":"SO:0002383"}


id: PBO:0036301
data:
  {"annotation_feature_type":"gene","cv_name":"genome_org","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"alternative transcripts, alternative splicing","termid":"PBO:0036301"}


id: PBO:0110367
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"EPS8 signaling adaptor L1","termid":"PBO:0110367"}


id: MOD:00586
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"modification from Unimod Chemical derivative","definition_xrefs":["Unimod:264"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Unimod","termid":"MOD:00003"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphorylation to pyridyl thiol","synonyms":[{"name":"PET","type":"related"},{"name":"phosphorylation to pyridyl thiol","type":"related"}],"termid":"MOD:00586"}


id: PBO:0002883
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2.7.7.52","termid":"PBO:0002883"}


id: MONDO:1011668
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"disorder of development or morphogenesis, non-human animal","termid":"MONDO:1011313"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"perosomus elumbis, non-human animal","secondary_identifiers":["OMIA:000789"],"termid":"MONDO:1011668","xrefs":{"Monarch":{"xref_id":"1011668"}}}


id: GO:0060264
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.","definition_xrefs":["GOC:rl","GOC:dph","GOC:BHF","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of immune effector process","termid":"GO:0002697"},{"relation_name":"is_a","term_name":"regulation of innate immune response","termid":"GO:0045088"},{"relation_name":"is_a","term_name":"regulation of inflammatory response","termid":"GO:0050727"},{"relation_name":"is_a","term_name":"regulation of multicellular organismal process","termid":"GO:0051239"},{"relation_name":"is_a","term_name":"regulation of respiratory burst","termid":"GO:0060263"},{"relation_name":"regulates","term_name":"respiratory burst involved in inflammatory response","termid":"GO:0002536"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of respiratory burst involved in inflammatory response","synonyms":[{"name":"regulation of respiratory burst involved in acute inflammatory response","type":"broad"}],"termid":"GO:0060264"}


id: PBO:0064363
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PMF1-BGLAP readthrough","termid":"PBO:0064363"}


id: PBO:0061232
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NOP9 nucleolar protein","termid":"PBO:0061232"}


id: GO:0004347
data:
  {"annotated_genes":["SJAG_00839"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[71946],"is_not":false,"summary":null,"term":"GO:0004347"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate.","definition_xrefs":["RHEA:11816"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intramolecular oxidoreductase activity, interconverting aldoses and ketoses","termid":"GO:0016861"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00839":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016853"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016853","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"glucose-6-phosphate isomerase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["MetaCyc:PGLUCISOM-RXN","Reactome:R-HSA-70471","Reactome:R-HSA-70475","EC:5.3.1.9"],"synonyms":[{"name":"D-glucose-6-phosphate aldose-ketose-isomerase activity","type":"related"},{"name":"D-glucose-6-phosphate ketol-isomerase activity","type":"related"},{"name":"glucose phosphate isomerase activity","type":"related"},{"name":"hexose monophosphate isomerase activity","type":"broad"},{"name":"hexose phosphate isomerase activity","type":"related"},{"name":"hexosephosphate isomerase activity","type":"broad"},{"name":"oxoisomerase activity","type":"related"},{"name":"phosphoglucoisomerase activity","type":"related"},{"name":"phosphoglucose isomerase activity","type":"related"},{"name":"phosphohexoisomerase activity","type":"broad"},{"name":"phosphohexomutase activity","type":"broad"},{"name":"phosphohexose isomerase activity","type":"broad"},{"name":"phosphosaccharomutase activity","type":"broad"}],"termid":"GO:0004347","terms_by_termid":{"GO:0004347":null}}


id: PR:Q9URX0
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC922.06 gene.","definition_xrefs":["UniProtKB:Q9URX0","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized oxidoreductase C922.06 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC922.06","synonyms":[{"name":"Spom972h-SPAC922.06","type":"exact"}],"termid":"PR:Q9URX0"}


id: PBO:0065564
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"prostaglandin E synthase 3 pseudogene 4","termid":"PBO:0065564"}


id: PBO:0039567
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ankyrin repeat domain 62 pseudogene 1","termid":"PBO:0039567"}


id: PBO:0081410
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 260","termid":"PBO:0081410"}


id: GO:0060892
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a cell becomes capable of differentiating autonomously into an limb basal epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.","definition_xrefs":["GOC:dph","GOC:sdb_2009","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epidermal cell fate specification","termid":"GO:0009957"},{"relation_name":"is_a","term_name":"cell fate specification involved in pattern specification","termid":"GO:0060573"},{"relation_name":"part_of","term_name":"limb epidermis stratification","termid":"GO:0060888"},{"relation_name":"part_of","term_name":"limb basal epidermal cell differentiation","termid":"GO:0060889"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"limb basal epidermal cell fate specification","termid":"GO:0060892"}


id: PBO:0045407
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DPPA3 pseudogene 9","termid":"PBO:0045407"}


id: PBO:0113199
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Member of the DRG family of GTP-binding proteins; associates with translating ribosomes; interacts with Tma46p, Ygr250cp, Gir2p and Yap1p via two-hybrid; localizes to cytosol and peroxisomes","termid":"PBO:0113199"}


id: MOD:00883
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces a 1-carboxyl group (usually referred to as the alpha-carboxyl) with a carboxamido group.","definition_xrefs":["DeltaMass:0","Unimod:2","OMSSA:25"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amidated residue","termid":"MOD:00674"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"C1-amidated residue","synonyms":[{"name":"Amidated","type":"related"},{"name":"Amidation","type":"related"},{"name":"Amide formation (C terminus)","type":"exact"},{"name":"ResN","type":"exact"},{"name":"alpha-amidated residue","type":"exact"},{"name":"ctermamide","type":"exact"}],"termid":"MOD:00883"}


id: PBO:0043602
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"collectin subfamily member 11","termid":"PBO:0043602"}


id: PBO:0090497
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"U3 snoRNP-associated protein Utp6","termid":"PBO:0090497"}


id: GO:0038154
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals initiated by the binding of interleukin-11 to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.","definition_xrefs":["GOC:nhn","GOC:signaling"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytokine-mediated signaling pathway","termid":"GO:0019221"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"interleukin-11-mediated signaling pathway","synonyms":[{"name":"IL-11-mediated signaling pathway","type":"exact"},{"name":"interleukin-11-mediated signalling pathway","type":"exact"}],"termid":"GO:0038154"}


id: PBO:0109129
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CRIPTO pseudogene 1","termid":"PBO:0109129"}


id: PBO:0087008
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ribokinase, phosphorylates ribose to ribose-5-phosphate; required for recycling ribose during nucleotide metabolism","termid":"PBO:0087008"}


id: PBO:0070998
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L21","termid":"PBO:0070998"}


id: MONDO:0016424
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Progressive sensorineural hearing loss - hypertrophic cardiomyopathy is an extremely rare disorder described in one family to date that is characterized by progressive, late onset, autosomal dominant sensorineural hearing loss, QT interval prolongation, and mild cardiac hypertrophy.","definition_xrefs":["Orphanet:228012"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hypertrophic cardiomyopathy","termid":"MONDO:0005045"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"progressive sensorineural hearing loss-hypertrophic cardiomyopathy syndrome","secondary_identifiers":["GARD:17145","UMLS:C4304831","MEDGEN:930500"],"synonyms":[{"name":"progressive neurosensory deafness-hypertrophic cardiomyopathy syndrome","type":"exact"},{"name":"progressive neurosensory hearing loss-hypertrophic cardiomyopathy syndrome","type":"exact"},{"name":"progressive sensorineural deafness-hypertrophic cardiomyopathy syndrome","type":"exact"}],"termid":"MONDO:0016424","xrefs":{"Monarch":{"xref_id":"0016424"}}}


id: PBO:0067322
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 413, pseudogene","termid":"PBO:0067322"}


id: PBO:0088583
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ketoreductase involved in fatty acid elongation","termid":"PBO:0088583"}


id: GO:0008714
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: AMP + H2O = D-ribose 5-phosphate + adenine.","definition_xrefs":["RHEA:20129","EC:3.2.2.4"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, hydrolyzing N-glycosyl compounds","termid":"GO:0016799"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016798"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016787","GO:0016798","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"AMP nucleosidase activity","secondary_identifiers":["MetaCyc:AMP-NUCLEOSID-RXN","KEGG_REACTION:R00182"],"synonyms":[{"name":"AMP phosphoribohydrolase activity","type":"related"},{"name":"adenosine monophosphate nucleosidase activity","type":"related"},{"name":"adenylate nucleosidase activity","type":"related"}],"termid":"GO:0008714"}


id: PBO:0079044
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Val (anticodon CAC) 1-6","termid":"PBO:0079044"}


id: PBO:0005715
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WD repeat protein, human WDR85 family, implicated in rRNA transcription","termid":"PBO:0005715"}


id: GO:0071885
data:
  {"annotated_genes":["SJAG_01425","SJAG_00508"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[64968,79096],"is_not":false,"summary":null,"term":"GO:0071885"}]},"cv_name":"molecular_function","definition":"Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the alpha-amino group of the N-terminal amino or imino acid residue of a protein substrate. For example, yeast Tae1p and mammalian family member METTL11A preferentially modify the N-terminal residue of substrates with the N-terminal sequence X-Pro-Lys, where X can be Pro, Ala, or Ser.","definition_xrefs":["PMID:20481588"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein methyltransferase activity","termid":"GO:0008276"},{"relation_name":"is_a","term_name":"S-adenosylmethionine-dependent methyltransferase activity","termid":"GO:0008757"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00508":null,"SJAG_01425":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0008276"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0016740","GO:0003824","GO:0008276","GO:0003674","GO:0140096","GO:0016741"],"is_obsolete":false,"name":"N-terminal protein N-methyltransferase activity","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000104":null},"secondary_identifiers":["EC:2.1.1.244"],"synonyms":[{"name":"X-Pro-Lys N-terminal methyltransferase","type":"narrow"}],"termid":"GO:0071885","terms_by_termid":{"GO:0071885":null}}


id: MONDO:0002251
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An active inflammatory process affecting the liver for more than six months. Causes include viral infections, autoimmune disorders, drugs, and metabolic disorders.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"liver disorder","termid":"MONDO:0005154"},{"relation_name":"is_a","term_name":"inflammatory disease","termid":"MONDO:0021166"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002515"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0002515"],"is_obsolete":false,"name":"hepatitis","secondary_identifiers":["ICD9:571.41","ICD9:571.4","DOID:2237","ICD9:571.40","NCIT:C3095","MESH:D006505","SCTID:197268000","ICD9:570","MEDGEN:5515","UMLS:C0019158"],"synonyms":[{"name":"Hepatitides","type":"related"},{"name":"Hepatitis","type":"exact"},{"name":"acute and subacute liver necrosis","type":"narrow"},{"name":"acute hepatitis","type":"narrow"},{"name":"acute/subac. necrosis of liver","type":"narrow"},{"name":"animal hepatitis","type":"narrow"},{"name":"chronic hepatitis","type":"narrow"},{"name":"chronic persistent hepatitis","type":"narrow"},{"name":"hepatitis","type":"exact"},{"name":"inflammation of liver","type":"exact"},{"name":"liver inflammation","type":"exact"}],"termid":"MONDO:0002251","xrefs":{"Monarch":{"xref_id":"0002251"}}}


id: GO:0019650
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The anaerobic chemical reactions and pathways resulting in the breakdown of glucose into butanediol; effected by some members of the Enterobacteriaceae, e.g. Enterobacter, Erwinia, Klebsiella, and Serratia.","definition_xrefs":["GOC:dph","GOC:nr","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glucose metabolic process","termid":"GO:0006006"},{"relation_name":"is_a","term_name":"glycolytic fermentation","termid":"GO:0019660"},{"relation_name":"is_a","term_name":"butanediol metabolic process","termid":"GO:0034077"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0006091"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006091","GO:0005975","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"glycolytic fermentation to butanediol","secondary_identifiers":["GO:0030646","Wikipedia:Butanediol_fermentation"],"synonyms":[{"name":"butanediol fermentation","type":"exact"},{"name":"glucose catabolic process to butanediol","type":"exact"},{"name":"glucose fermentation to butanediol","type":"exact"}],"termid":"GO:0019650"}


id: PBO:0116987
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FRMD4A antisense RNA 2","termid":"PBO:0116987"}


id: PBO:0046902
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 25 member A","termid":"PBO:0046902"}


id: PBO:0041744
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CAMTA1 antisense RNA 1","termid":"PBO:0041744"}


id: MONDO:0004922
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A disorder characterized by an impairment in the development of an individual's motor coordination skills; this impairment in motor development is not due to a medical condition.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"specific developmental disorder","termid":"MONDO:0000592"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"developmental coordination disorder","secondary_identifiers":["UMLS:C0011757","NCIT:C92561","ICD9:315.4","MESH:D019957","MEDGEN:41511","SCTID:27544004","DOID:9923"],"synonyms":[{"name":"clumsy child syndrome","type":"exact"},{"name":"development coordination disorder","type":"exact"},{"name":"developmental dyspraxia","type":"exact"}],"termid":"MONDO:0004922","xrefs":{"Monarch":{"xref_id":"0004922"}}}


id: GO:1903112
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of single-strand break repair via homologous recombination.","definition_xrefs":["GO_REF:0000058","PMID:24339919","GOC:TermGenie","GOC:bhm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of DNA recombination","termid":"GO:0045911"},{"relation_name":"is_a","term_name":"regulation of single-strand break repair via homologous recombination","termid":"GO:1903110"},{"relation_name":"is_a","term_name":"positive regulation of single strand break repair","termid":"GO:1903518"},{"relation_name":"positively_regulates","term_name":"single-strand break repair via homologous recombination","termid":"GO:1990396"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006310"},{"rel_name":"positively_regulates","termid":"GO:0006259"},{"rel_name":"regulates","termid":"GO:0006259"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0006281"},{"rel_name":"positively_regulates","termid":"GO:0006310"},{"rel_name":"regulates","termid":"GO:0006281"}],"interesting_parent_ids":["GO:0008150","GO:0006281","GO:0006310","GO:0006259"],"is_obsolete":false,"name":"positive regulation of single-strand break repair via homologous recombination","synonyms":[{"name":"activation of single-strand break repair via homologous recombination","type":"narrow"},{"name":"up regulation of single-strand break repair via homologous recombination","type":"exact"},{"name":"up-regulation of single-strand break repair via homologous recombination","type":"exact"},{"name":"upregulation of single-strand break repair via homologous recombination","type":"exact"}],"termid":"GO:1903112"}


id: MONDO:0015229
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A ciliopathy with multisystem involvement. It is invariantly characterized by rod-cone dystrophy, and at least three additional non-ocular features such as intellectual disability, obesity, polydactyly, hypogonadism, or renal anomalies as primary manifestations. In the absence of one of these four primary clinical features, the diagnosis of BBS is made when at least two secondary features are observed, including hepatic fibrosis, diabetes mellitus, reproductive and developmental abnormalities, growth retardation, speech delays, or cardiovascular problems","definition_xrefs":["Orphanet:110","PMID:10874630"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"multiple congenital anomalies/dysmorphic syndrome-variable intellectual disability syndrome","termid":"MONDO:0015160"},{"relation_name":"excluded_subClassOf","term_name":"congenital hypogonadotropic hypogonadism","termid":"MONDO:0015770"},{"relation_name":"excluded_subClassOf","term_name":"obsolete syndromic genetic obesity (obsolete MONDO:0016565)","termid":"MONDO:0016565"},{"relation_name":"excluded_subClassOf","term_name":"familial cystic renal disease","termid":"MONDO:0019741"},{"relation_name":"excluded_subClassOf","term_name":"obsolete syndromic retinitis pigmentosa (obsolete MONDO:0020240)","termid":"MONDO:0020240"},{"relation_name":"excluded_subClassOf","term_name":"female infertility","termid":"MONDO:0021124"},{"relation_name":"excluded_subClassOf","term_name":"intestinal motility disease","termid":"MONDO:0021189"},{"relation_name":"excluded_subClassOf","term_name":"obsolete genetic multiple congenital anomalies/dysmorphic syndrome-variable intellectual disability syndrome (obsolete MONDO:0043007)","termid":"MONDO:0043007"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"ciliopathy","termid":"MONDO:0005308"},{"relation_name":"is_a","term_name":"autosomal recessive disease","termid":"MONDO:0006025"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0006025"],"is_obsolete":false,"name":"Bardet-Biedl syndrome","secondary_identifiers":["MedDRA:10056715","NORD:838","SCTID:5619004","GARD:6866","icd11.foundation:255526264","DOID:1935","MEDGEN:156019","NANDO:2200414","NCIT:C118632","OMIMPS:209900","UMLS:C0752166","MESH:D020788","ICD9:759.89"],"synonyms":[{"name":"BBS","type":"exact"},{"name":"Bardet-Biedl syndrome","type":"exact"}],"termid":"MONDO:0015229","xrefs":{"Monarch":{"xref_id":"0015229"}}}


id: _global:transcribed_from
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"X is transcribed_from Y if X is synthesized from template Y.","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcribed_from","termid":"_global:transcribed_from"}


id: PBO:0074284
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SLIT3 antisense RNA 1","termid":"PBO:0074284"}


id: GO:1904810
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule transport.","definition_xrefs":["GOC:TermGenie","PMID:22699897","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of intracellular transport","termid":"GO:0032387"},{"relation_name":"is_a","term_name":"regulation of dense core granule transport","termid":"GO:1904809"},{"relation_name":"negatively_regulates","term_name":"dense core granule transport","termid":"GO:1901950"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"negatively_regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810"],"is_obsolete":false,"name":"negative regulation of dense core granule transport","synonyms":[{"name":"down regulation of dense core granule transport","type":"exact"},{"name":"down regulation of dense core vesicle transport","type":"exact"},{"name":"down-regulation of dense core granule transport","type":"exact"},{"name":"down-regulation of dense core vesicle transport","type":"exact"},{"name":"downregulation of dense core granule transport","type":"exact"},{"name":"downregulation of dense core vesicle transport","type":"exact"},{"name":"inhibition of dense core granule transport","type":"narrow"},{"name":"inhibition of dense core vesicle transport","type":"narrow"},{"name":"negative regulation of dense core vesicle transport","type":"exact"}],"termid":"GO:1904810"}


id: PBO:0001528
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TOR signaling pathway transcriptional corepressor Crf1 (predicted)","termid":"PBO:0001528"}


id: PBO:0058357
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4730","termid":"PBO:0058357"}


id: PBO:0108540
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cyclin Y like 1B","termid":"PBO:0108540"}


id: PBO:0005419
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vigilin (predicted)","termid":"PBO:0005419"}


id: PBO:0085264
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Permease of basic amino acids in the vacuolar membrane; VBA3 has a paralog, VBA5, that arose from a segmental duplication","termid":"PBO:0085264"}


id: PBO:0054227
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1609","termid":"PBO:0054227"}


id: MONDO:1010712
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Trimethylaminuria (fishy taint) that occurs in cattle.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"trimethylaminuria (fishy taint), non-human animal","termid":"MONDO:1010104"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"trimethylaminuria (fishy taint), cattle","secondary_identifiers":["OMIA:001360-9913"],"termid":"MONDO:1010712","xrefs":{"Monarch":{"xref_id":"1010712"}}}


id: GO:0006031
data:
  {"annotated_genes":["SJAG_03723","SJAG_04868","SJAG_02845","SJAG_00978","SJAG_00442","SJAG_04728"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[72737,73672,75979,76187,80090,111897],"is_not":false,"summary":null,"term":"GO:0006031"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.","definition_xrefs":["GOC:jl","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"aminoglycan biosynthetic process","termid":"GO:0006023"},{"relation_name":"is_a","term_name":"chitin metabolic process","termid":"GO:0006030"},{"relation_name":"is_a","term_name":"glucosamine-containing compound biosynthetic process","termid":"GO:1901073"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00442":null,"SJAG_00978":null,"SJAG_02845":null,"SJAG_03723":null,"SJAG_04728":null,"SJAG_04868":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"chitin biosynthetic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["MetaCyc:PWY-6981"],"synonyms":[{"name":"beta-1,4-linked N-acetylglucosamine biosynthesis","type":"exact"},{"name":"beta-1,4-linked N-acetylglucosamine biosynthetic process","type":"exact"},{"name":"chitin anabolism","type":"exact"},{"name":"chitin biosynthesis","type":"exact"},{"name":"chitin formation","type":"exact"},{"name":"chitin synthesis","type":"exact"}],"termid":"GO:0006031","terms_by_termid":{"GO:0006031":null}}


id: PBO:0058269
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4647","termid":"PBO:0058269"}


id: MONDO:0012175
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A cataract that has material basis in variation in the region 6p12-q12.","definition_xrefs":["DOID:0110244","PMID:15452352"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cataract","termid":"MONDO:0005129"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"cataract 28","secondary_identifiers":["MEDGEN:373214","MESH:C563812","OMIM:609026","UMLS:C1836942"],"synonyms":[{"name":"ARCC1","type":"exact"},{"name":"CTRCT28","type":"exact"},{"name":"age-related cortical cataract 1","type":"exact"},{"name":"cataract 28","type":"exact"},{"name":"cataract 28, age-related cortical, susceptibility to","type":"exact"},{"name":"cataract type 28","type":"exact"},{"name":"cataract, age-related cortical, 1","type":"related"}],"termid":"MONDO:0012175","xrefs":{"Monarch":{"xref_id":"0012175"}}}


id: FYPO:0006645
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone during metaphase is normal (i.e. indistinguishable from wild type). The mitotic spindle midzone is the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap.","definition_xrefs":["GO:1990023","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein localization to mitotic spindle midzone","termid":"FYPO:0004692"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000138"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0001312","FYPO:0000002","FYPO:0000138","FYPO:0000257"],"is_obsolete":false,"name":"normal protein localization to mitotic spindle midzone during metaphase","synonyms":[{"name":"normal protein localisation to mitotic spindle midzone during metaphase","type":"exact"},{"name":"normal protein localization to mitotic spindle midzone during metaphase during vegetative growth","type":"exact"},{"name":"normal protein localization to spindle midzone during metaphase during mitotic cell cycle","type":"exact"}],"termid":"FYPO:0006645"}


id: PBO:0038410
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-characteristic_of_part_of","termid":"PBO:0038410"}


id: PBO:0111868
data:
  {"annotation_feature_type":"gene","cv_name":"pombase_family_or_domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zf-ZZ type","termid":"PBO:0111868"}


id: PBO:0054366
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1760","termid":"PBO:0054366"}


id: MONDO:0007228
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"brachymesomelia-renal syndrome","secondary_identifiers":["MEDGEN:350586","MESH:C537096","OMIM:113470","UMLS:C1862084"],"synonyms":[{"name":"brachymesomelia renal syndrome","type":"related"},{"name":"brachymesomelia-renal syndrome","type":"exact"},{"name":"severe upper limb brachymesomelia, glomerulocystic renal dysplasia, cranial and facial abnormalities, corneal opacities","type":"related"}],"termid":"MONDO:0007228","xrefs":{"Monarch":{"xref_id":"0007228"}}}


id: PBO:0079977
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"USP9Y pseudogene 15","termid":"PBO:0079977"}


id: GO:0006577
data:
  {"annotated_genes":["SJAG_00832","SJAG_03856"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[113392,105446],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0052699"},{"annotations":[72672,105447],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903257"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving any betaine, the N-trimethyl derivative of an amino acid.","definition_xrefs":["GOC:mah","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified amino acid metabolic process","termid":"GO:0006575"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00832":null,"SJAG_03856":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"amino-acid betaine metabolic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"betaine metabolic process","type":"exact"},{"name":"betaine metabolism","type":"exact"}],"termid":"GO:0006577","terms_by_termid":{"GO:0052699":null,"GO:1903257":null}}


id: MONDO:0024913
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Diseases of domestic cattle of the genus Bos. It includes diseases of cows, yaks, and zebus.","definition_xrefs":["MESH:D002418"],"direct_ancestors":[{"relation_name":"is_a","term_name":"non-human animal disease","termid":"MONDO:0005583"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cattle disease","synonyms":[{"name":"bovine disease","type":"related"},{"name":"bovine diseases","type":"related"},{"name":"cattle disease","type":"exact"},{"name":"disease, bovine","type":"related"},{"name":"disease, cattle","type":"related"},{"name":"diseases, bovine","type":"related"},{"name":"diseases, cattle","type":"related"}],"termid":"MONDO:0024913","xrefs":{"Monarch":{"xref_id":"0024913"}}}


id: MONDO:0010090
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Summitt syndrome is an extremely rare disorder originally described in two brothers and characterized by mild to severe craniosynostosis and syndactyly, obesity, and normal intelligence. Acrocephaly, brachydactyly, clinodactyly, mild syndactyly of the hands and feet, genu valgum and marked obesity were later described in another patient. There have been no further descriptions in the literature since 1979. Summitt syndrome could be a variant of Carpenter syndrome.","definition_xrefs":["Orphanet:3210"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic craniosynostosis","termid":"MONDO:0015338"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"Summitt syndrome","secondary_identifiers":["SCTID:733606001","UMLS:C1802405","MEDGEN:369198","OMIM:272350","ICD10CM:Q82.0","GARD:127","MESH:C538142","NORD:1746"],"synonyms":[{"name":"Summitt syndrome","type":"exact"},{"name":"Summitt's acrocephalosyndactyly","type":"related"},{"name":"recessive acrocephalosyndactyly with normal intelligence","type":"related"}],"termid":"MONDO:0010090","xrefs":{"Monarch":{"xref_id":"0010090"}}}


id: PR:Q9P6J0
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPBC1683.12 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9P6J0"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized transporter C1683.12 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC1683.12","synonyms":[{"name":"Spom972h-SPBC1683.12","type":"exact"}],"termid":"PR:Q9P6J0"}


id: MONDO:0033618
data:
  {"annotated_genes":["SJAG_03597"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87505],"is_not":false,"summary":null,"term":"MONDO:0033618"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03597":null},"genotype_count":0,"is_obsolete":false,"name":"Vissers-Bodmer syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1776566","DOID:0081397","UMLS:C5436647","OMIM:619033"],"synonyms":[{"name":"VIBOS","type":"exact"}],"termid":"MONDO:0033618","terms_by_termid":{"MONDO:0033618":null},"xrefs":{"Monarch":{"xref_id":"0033618"}}}


id: PBO:0057607
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 941-4","termid":"PBO:0057607"}


id: PBO:0035952
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_histone_H4-K5_acetylation_during_vegetative_growth","termid":"PBO:0035952"}


id: PBO:0063562
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proline, glutamate and leucine rich protein 1","termid":"PBO:0063562"}


id: GO:0044045
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. An interaction with the host organism mediated by a substance in the symbiont cell outer membrane - a lipid bilayer that forms the outermost layer of the symbiont cell envelope. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["MITRE:tk"],"gene_count":0,"genotype_count":0,"name":"obsolete interaction with host via substance in symbiont cell outer membrane (obsolete GO:0044045)","termid":"GO:0044045"}


id: GO:0005666
data:
  {"annotated_genes":["SJAG_03761","SJAG_03035","SJAG_03921","SJAG_03181","SJAG_00637","SJAG_04261","SJAG_00731","SJAG_01444","SJAG_04934","SJAG_04161","SJAG_00619","SJAG_04408","SJAG_01765","SJAG_02070","SJAG_02600","SJAG_02101","SJAG_01313"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[57205,64236,71840,72805,72869,73037,75190,75897,76740,76924,77277,78283,78599,78705,81415,81553,118626],"is_not":false,"summary":null,"term":"GO:0005666"}]},"cv_name":"cellular_component","definition":"RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.","definition_xrefs":["GOC:mtg_sensu","GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nuclear DNA-directed RNA polymerase complex","termid":"GO:0055029"}],"gene_count":17,"genes_by_uniquename":{"SJAG_00619":null,"SJAG_00637":null,"SJAG_00731":null,"SJAG_01313":null,"SJAG_01444":null,"SJAG_01765":null,"SJAG_02070":null,"SJAG_02101":null,"SJAG_02600":null,"SJAG_03035":null,"SJAG_03181":null,"SJAG_03761":null,"SJAG_03921":null,"SJAG_04161":null,"SJAG_04261":null,"SJAG_04408":null,"SJAG_04934":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005634"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0032991","GO:0005634","GO:0005575"],"is_obsolete":false,"name":"RNA polymerase III complex","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000104":null,"GO_REF:0000107":null,"GO_REF:0000117":null},"synonyms":[{"name":"DNA-directed RNA polymerase III activity","type":"related"},{"name":"DNA-directed RNA polymerase III complex","type":"exact"}],"termid":"GO:0005666","terms_by_termid":{"GO:0005666":null}}


id: PBO:0034793
data:
  {"annotation_feature_type":"gene","cv_name":"misc","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"this gene product was previously annotated to the NADH dehydrogenase of the mitochondrial respiratory chain complex I. This mapping was removed because fission yeast lacks the remaining 40 subunits found in mammals (PMID:1518044).","termid":"PBO:0034793"}


id: PBO:0088674
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"arrestin-related substrate adaptor Rod1","termid":"PBO:0088674"}


id: PBO:0067597
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 760, pseudogene","termid":"PBO:0067597"}


id: GO:0030486
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"Electron-dense region associated with a smooth muscle contractile fiber.","definition_xrefs":["GOC:mah","ISBN:0815316194"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"smooth muscle contractile fiber","termid":"GO:0030485"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0005737","GO:0005575"],"is_obsolete":false,"name":"smooth muscle dense body","termid":"GO:0030486"}


id: PBO:0017673
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Schizosaccharomyces specific protein New2","termid":"PBO:0017673"}


id: GO:0045547
data:
  {"annotated_genes":["SJAG_02163","SJAG_00554"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[73800,76175],"is_not":false,"summary":null,"term":"GO:0045547"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + n isopentenyl diphosphate = a di-trans,poly-cis-polyprenyl diphosphate + n diphosphate.","definition_xrefs":["RHEA:53008","PMID:9858571"],"direct_ancestors":[{"relation_name":"is_a","term_name":"prenyl diphosphate synthase activity","termid":"GO:0120531"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00554":null,"SJAG_02163":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016765"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016740","GO:0016765"],"is_obsolete":false,"name":"ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["EC:2.5.1.87"],"synonyms":[{"name":"dehydrodolichyl diphosphate synthase activity","type":"exact"}],"termid":"GO:0045547","terms_by_termid":{"GO:0045547":null}}


id: MONDO:0012447
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"non-syndromic synpolydactyly","termid":"MONDO:0000722"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"synpolydactyly type 3","secondary_identifiers":["GARD:17360","MEDGEN:344005","icd11.foundation:1671501762","Orphanet:295199","UMLS:C1853255","MESH:C565216","OMIM:610234"],"synonyms":[{"name":"SD2, Malik type","type":"exact"},{"name":"SD2c","type":"exact"},{"name":"SPD, Malik type","type":"exact"},{"name":"SPD3","type":"exact"},{"name":"synpolydactyly 3","type":"related"},{"name":"synpolydactyly, Malik type","type":"exact"}],"termid":"MONDO:0012447","xrefs":{"Monarch":{"xref_id":"0012447"}}}


id: PBO:0083853
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; predicted to contain both S1 and KH RNA binding domains; mutations in the human homolog, EXOSC3, cause pontocerebellar hypoplasia with motor neuron degeneration","termid":"PBO:0083853"}


id: PBO:0089559
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial translation elongation factor G Mef1","termid":"PBO:0089559"}


id: MONDO:0017677
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"punctate palmoplantar keratoderma","termid":"MONDO:0017675"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"focal acral hyperkeratosis","secondary_identifiers":["MEDGEN:724380","GARD:21299","Orphanet:308013","SCTID:400115004","UMLS:C1302839"],"synonyms":[{"name":"PPKP3 without elastoidosis","type":"exact"},{"name":"PPPK3 without elastoidosis","type":"exact"},{"name":"punctate palmoplantar hyperkeratosis type 3 without elastoidosis","type":"exact"},{"name":"punctate palmoplantar keratoderma type 3 without elastoidosis","type":"exact"}],"termid":"MONDO:0017677","xrefs":{"Monarch":{"xref_id":"0017677"}}}


id: GO:0019056
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process in which a virus modulates the frequency, rate or extent of its host's transcription.","definition_xrefs":["PMID:7799962"],"gene_count":0,"genotype_count":0,"name":"obsolete modulation by virus of host transcription (obsolete GO:0019056)","synonyms":[{"name":"modification of host transcription","type":"exact"},{"name":"modulation by virus of host transcription","type":"narrow"},{"name":"perturbation of host cell transcription","type":"exact"}],"termid":"GO:0019056"}


id: PBO:0013811
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by G. gallus cdc2","termid":"PBO:0013811"}


id: PBO:0076894
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"testis expressed 48","termid":"PBO:0076894"}


id: GO:2000925
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of cellodextrin metabolic process.","definition_xrefs":["GOC:mengo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of macromolecule metabolic process","termid":"GO:0010605"},{"relation_name":"is_a","term_name":"negative regulation of carbohydrate metabolic process","termid":"GO:0045912"},{"relation_name":"is_a","term_name":"regulation of cellodextrin metabolic process","termid":"GO:2000924"},{"relation_name":"negatively_regulates","term_name":"cellodextrin metabolic process","termid":"GO:2000889"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0005975"},{"rel_name":"negatively_regulates","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0005975","GO:0008150"],"is_obsolete":false,"name":"negative regulation of cellodextrin metabolic process","synonyms":[{"name":"negative regulation of cellodextrin metabolism","type":"exact"}],"termid":"GO:2000925"}


id: PBO:0034798
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitotic cohesin N-acetyltransferase/DNA polymerase eta Eso1 fusion protein","termid":"PBO:0034798"}


id: GO:0075032
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont germ tube hook structure formation.","definition_xrefs":["GOC:pamgo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of developmental process","termid":"GO:0051093"},{"relation_name":"is_a","term_name":"modulation of formation of symbiont germ tube hook structure for appressorium development","termid":"GO:0075030"},{"relation_name":"negatively_regulates","term_name":"formation of appressorium germ tube hook structure","termid":"GO:0075029"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of formation of symbiont germ tube hook structure for appressorium development","synonyms":[{"name":"negative regulation of formation of symbiont germ tube hook structure on or near host","type":"exact"},{"name":"negative regulation of germ tube tip of symbiont on or near the exterior of host","type":"exact"},{"name":"negative regulation of symbiont germ tube hook structure formation on or near host","type":"related"}],"termid":"GO:0075032"}


id: PBO:0062761
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 52 subfamily P member 1 (gene/pseudogene)","termid":"PBO:0062761"}


id: GO:0061652
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Isoenergetic transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y = Y-FAT10 + X, where both the X-FAT10 and Y-FAT10 linkages are thioester bonds between the C-terminal amino acid of FAT10 and a sulfhydryl side group of a cysteine residue.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"FAT10 transferase activity","termid":"GO:0019775"},{"relation_name":"is_a","term_name":"ubiquitin-like protein conjugating enzyme activity","termid":"GO:0061650"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0019787"},{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0140096","GO:0003824","GO:0016740","GO:0019787","GO:0003674","GO:0016746"],"is_obsolete":false,"name":"FAT10 conjugating enzyme activity","synonyms":[{"name":"E2","type":"broad"}],"termid":"GO:0061652"}


id: PomGeneEx:0000025
data:
  {"annotation_feature_type":"gene","cv_name":"PomGeneExRD","definition":"A qualifier that describes the fraction of ribosomes that are translating each codon of an mRNA, and reflects the average time spent by the ribosome on each codon.","definition_xrefs":["PMID:33313903","PMID:29432178","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gene expression qualifier","termid":"PomGeneEx:0000001"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal density","synonyms":[{"name":"ribosome density","type":"exact"},{"name":"ribosome occupancy","type":"exact"}],"termid":"PomGeneEx:0000025"}


id: PBO:0076678
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcription elongation factor A1 pseudogene 3","termid":"PBO:0076678"}


id: GO:0051733
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: NTP + 5'-dephospho-DNA = NDP + 5'-phospho-DNA.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete polydeoxyribonucleotide kinase activity (obsolete GO:0051733)","synonyms":[{"name":"DNA 5'-hydroxyl kinase activity","type":"exact"},{"name":"DNA kinase activity","type":"exact"}],"termid":"GO:0051733"}


id: PBO:0083063
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dihydroorotase; catalyzes the third enzymatic step in the de novo biosynthesis of pyrimidines, converting carbamoyl-L-aspartate into dihydroorotate","termid":"PBO:0083063"}


id: GO:0002758
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals generated by a ligand binding to its receptor that lead to the activation or perpetuation of an innate immune response.","definition_xrefs":["GOC:mah","GOC:jy","PMID:11418339","PMID:28105028"],"direct_ancestors":[{"relation_name":"is_a","term_name":"activation of innate immune response","termid":"GO:0002218"},{"relation_name":"is_a","term_name":"immune response-activating signaling pathway","termid":"GO:0002757"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"innate immune response-activating signaling pathway","secondary_identifiers":["GO:0009870","GO:0010204"],"synonyms":[{"name":"defence response signaling pathway, resistance gene-dependent","type":"related"},{"name":"defence response signaling pathway, resistance gene-independent","type":"related"},{"name":"defence response signalling pathway, resistance gene-dependent","type":"related"},{"name":"defence response signalling pathway, resistance gene-independent","type":"related"},{"name":"defense response signaling pathway, resistance gene-dependent","type":"related"},{"name":"defense response signaling pathway, resistance gene-independent","type":"related"},{"name":"defense response signalling pathway, resistance gene-dependent","type":"related"},{"name":"effector triggered immunity","type":"broad"},{"name":"effector-triggered immune signaling","type":"related"},{"name":"effector-triggered immunity","type":"broad"}],"termid":"GO:0002758"}


id: GO:0065007
data:
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id: MONDO:0010667
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id: MONDO:0018062
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id: PBO:0027185
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id: SO:0002283
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id: PBO:0077691
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id: MONDO:0020291
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id: GO:0033799
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id: PBO:0050924
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id: GO:0010542
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id: MONDO:0014493
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A somatic mutation in the CTLA4 gene resulting in only a single functional gene. Haploinsufficiency for CTLA4 is associated with autoimmune lymphoproliferative syndrome, type V.","definition_xrefs":["NCIT:C126341"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autoimmune lymphoproliferative syndrome","termid":"MONDO:0017979"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"autoimmune lymphoproliferative syndrome due to CTLA4 haploinsufficiency","secondary_identifiers":["GARD:12316","OMIM:616100","MEDGEN:863651","Orphanet:436159","UMLS:C4015214"],"synonyms":[{"name":"ALPS due to CTLA4 haploinsufficiency","type":"exact"},{"name":"ALPS type 5","type":"exact"},{"name":"ALPS type V","type":"exact"},{"name":"ALPS5","type":"related"},{"name":"CHAI","type":"exact"},{"name":"CTLA-4 haploinsufficiency with autoimmune infiltration disease","type":"exact"},{"name":"CTLA4 haploinsufficiency","type":"exact"},{"name":"CTLA4 haploinsufficiency with autoimmune infiltration","type":"related"},{"name":"autoimmune lymphoproliferative syndrome due to CTLA4 haploinsufficiency","type":"exact"},{"name":"autoimmune lymphoproliferative syndrome type 5","type":"exact"},{"name":"autoimmune lymphoproliferative syndrome type V","type":"exact"},{"name":"autoimmune lymphoproliferative syndrome, type 5","type":"related"},{"name":"autoimmune lymphoproliferative syndrome, type V","type":"related"},{"name":"chai","type":"exact"},{"name":"immune dysregulation with autoimmunity, immunodeficiency, and lymphoproliferation","type":"exact"}],"termid":"MONDO:0014493","xrefs":{"Monarch":{"xref_id":"0014493"}}}


id: PBO:0027148
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_farnesyltranstransferase_activity","termid":"PBO:0027148"}


id: GO:2000369
data:
  {"annotated_genes":["SJAG_04052","SJAG_04465","SJAG_00649"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[112876,113523,120739],"is_not":false,"summary":null,"term":"GO:2000369"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of clathrin-mediated endocytosis.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of receptor-mediated endocytosis","termid":"GO:0048259"},{"relation_name":"regulates","term_name":"clathrin-dependent endocytosis","termid":"GO:0072583"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00649":null,"SJAG_04052":null,"SJAG_04465":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0016192"}],"interesting_parent_ids":["GO:0016192","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"regulation of clathrin-dependent endocytosis","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"regulation of clathrin coated pit-dependent endocytosis","type":"exact"},{"name":"regulation of clathrin-mediated endocytosis","type":"exact"}],"termid":"GO:2000369","terms_by_termid":{"GO:2000369":null}}


id: MONDO:0030981
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"severe combined immunodeficiency","termid":"MONDO:0015974"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"immunodeficiency 79","secondary_identifiers":["MEDGEN:1783683","UMLS:C5543220","OMIM:619238","GARD:9523","DOID:0112277"],"synonyms":[{"name":"CD4 Deficiency","type":"exact"},{"name":"IMD79","type":"exact"},{"name":"immunodeficiency 79","type":"exact"}],"termid":"MONDO:0030981","xrefs":{"Monarch":{"xref_id":"0030981"}}}


id: GO:0016578
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The modification of histones by removal of ubiquitin groups.","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete histone deubiquitination (obsolete GO:0016578)","synonyms":[{"name":"histone deubiquitinylation","type":"exact"},{"name":"histone deubiquitylation","type":"exact"}],"termid":"GO:0016578"}


id: PBO:0054062
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1409","termid":"PBO:0054062"}


id: PBO:0082995
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cytosolic leucyl tRNA synthetase; ligates leucine to the appropriate tRNA; human homolog LARS can complement yeast temperature-sensitive mutant at restrictive temperature","termid":"PBO:0082995"}


id: PBO:0058628
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 6760","termid":"PBO:0058628"}


id: PBO:0077861
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tropomyosin 3 pseudogene 2","termid":"PBO:0077861"}


id: GO:1900452
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of long term synaptic depression.","definition_xrefs":["GOC:TermGenie","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of synaptic plasticity","termid":"GO:0048167"},{"relation_name":"regulates","term_name":"long-term synaptic depression","termid":"GO:0060292"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"regulation of long-term synaptic depression","synonyms":[{"name":"regulation of LTD","type":"related"},{"name":"regulation of long term depression","type":"broad"},{"name":"regulation of long term synaptic depression","type":"exact"}],"termid":"GO:1900452"}


id: GO:0008035
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to high-density lipoprotein particle, a lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lipoprotein particle binding","termid":"GO:0071813"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005488"],"is_obsolete":false,"name":"high-density lipoprotein particle binding","synonyms":[{"name":"HDL binding","type":"exact"}],"termid":"GO:0008035"}


id: PBO:0051778
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"IQ motif containing B1","termid":"PBO:0051778"}


id: MONDO:0021092
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign or malignant neoplasm affecting the fallopian tube. Representative examples of benign neoplasms include papilloma, adenofibroma, and leiomyoma. Representative examples of malignant neoplasms include carcinoma, carcinosarcoma, and adenosarcoma.","definition_xrefs":["NCIT:C3032"],"direct_ancestors":[{"relation_name":"is_a","term_name":"fallopian tube disorder","termid":"MONDO:0002156"},{"relation_name":"is_a","term_name":"female reproductive system neoplasm","termid":"MONDO:0021148"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fallopian tube neoplasm","secondary_identifiers":["MEDGEN:8775","ICD9:239.5","MESH:D005185","SCTID:126916003","UMLS:C0015558"],"synonyms":[{"name":"fallopian tube neoplasm","type":"exact"},{"name":"fallopian tube neoplasm (disease)","type":"exact"},{"name":"fallopian tube tumor","type":"exact"},{"name":"fallopian tube tumour","type":"exact"},{"name":"neoplasm of fallopian tube","type":"exact"},{"name":"neoplasm of the fallopian tube","type":"exact"},{"name":"tumor of fallopian tube","type":"exact"},{"name":"tumor of the fallopian tube","type":"exact"},{"name":"tumour of fallopian tube","type":"exact"},{"name":"tumour of the fallopian tube","type":"exact"}],"termid":"MONDO:0021092","xrefs":{"Monarch":{"xref_id":"0021092"}}}


id: PR:Q9P6K7
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- asc1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9P6K7"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-aminoacylation cofactor arc1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC30C2.04","synonyms":[{"name":"Spom972h-asc1","type":"exact"}],"termid":"PR:Q9P6K7"}


id: PBO:0060056
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-ND5 pseudogene 3","termid":"PBO:0060056"}


id: GO:0021832
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The attachment of cells to one another to form groups of cells involved in cerebral cortex tangential migration.","definition_xrefs":["PMID:12626695","GOC:jid","GO_REF:0000021","GOC:dgh","GOC:dph","GOC:cls"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell-cell adhesion via plasma-membrane adhesion molecules","termid":"GO:0098742"},{"relation_name":"part_of","term_name":"cerebral cortex tangential migration using cell-cell interactions","termid":"GO:0021823"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0007155"}],"interesting_parent_ids":["GO:0008150","GO:0007155"],"is_obsolete":false,"name":"cell-cell adhesion involved in cerebral cortex tangential migration using cell-cell interactions","termid":"GO:0021832"}


id: PBO:0001002
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"thiamine transporter Thi9","termid":"PBO:0001002"}


id: PBO:0089118
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiotic spindle pole body KASH domain protein Kms1","termid":"PBO:0089118"}


id: GO:0051328
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The cell cycle phase which begins after cytokinesis and ends when meiotic prophase begins. Meiotic cells have an interphase after each meiotic division, but only interphase I involves replication of the cell's DNA.","definition_xrefs":["GOC:mtg_cell_cycle"],"direct_ancestors":[{"relation_name":"is_a","term_name":"interphase","termid":"GO:0051325"},{"relation_name":"is_a","term_name":"meiotic cell cycle phase","termid":"GO:0098762"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"meiotic interphase","synonyms":[{"name":"interphase of meiotic cell cycle","type":"exact"}],"termid":"GO:0051328"}


id: MONDO:0020283
data:
  {"annotated_genes":["SJAG_00856","SJAG_01756"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[89071],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009624"},{"annotations":[87036],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014592"}]},"cv_name":"mondo","definition":"An inflammatory process affecting a part of or the entire uvea. Causes include inflammatory agents (e.g., herpes simplex, herpes zoster, leptospirosis) and systemic diseases (e.g., inflammatory bowel disease, multiple sclerosis, systemic lupus erythematosus, ankylosing spondylitis). Patients present with pain and redness in the eye, light sensitivity, and blurred and decreased vision.","definition_xrefs":["NCIT:C26909"],"direct_ancestors":[{"relation_name":"is_a","term_name":"uveal disorder","termid":"MONDO:0002661"},{"relation_name":"is_a","term_name":"inflammatory disease","termid":"MONDO:0021166"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00856":null,"SJAG_01756":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"uveitis","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["Orphanet:98715","SCTID:128473001","MESH:D014605","UMLS:C0042164","MEDGEN:52961","EFO:1001231","GARD:19549","HP:0000554","DOID:13141","MedDRA:10046851"],"synonyms":[{"name":"inflammation of uvea","type":"exact"},{"name":"uvea inflammation","type":"exact"},{"name":"uveitis","type":"exact"},{"name":"uveitis (disease)","type":"exact"}],"termid":"MONDO:0020283","terms_by_termid":{"MONDO:0009624":null,"MONDO:0014592":null},"xrefs":{"Monarch":{"xref_id":"0020283"}}}


id: PBO:0080453
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"visinin like 1","termid":"PBO:0080453"}


id: PBO:0044468
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome P450 family 7 subfamily A member 1","termid":"PBO:0044468"}


id: GO:0045937
data:
  {"annotated_genes":["SJAG_02613","SJAG_00685"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[119397],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1902648"},{"annotations":[91509],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905857"}]},"cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of phosphorus metabolic process","termid":"GO:0010562"},{"relation_name":"is_a","term_name":"regulation of phosphate metabolic process","termid":"GO:0019220"},{"relation_name":"positively_regulates","term_name":"phosphate-containing compound metabolic process","termid":"GO:0006796"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00685":null,"SJAG_02613":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of phosphate metabolic process","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"activation of phosphate metabolic process","type":"narrow"},{"name":"positive regulation of phosphate metabolism","type":"exact"},{"name":"stimulation of phosphate metabolic process","type":"narrow"},{"name":"up regulation of phosphate metabolic process","type":"exact"},{"name":"up-regulation of phosphate metabolic process","type":"exact"},{"name":"upregulation of phosphate metabolic process","type":"exact"}],"termid":"GO:0045937","terms_by_termid":{"GO:1902648":null,"GO:1905857":null}}


id: MONDO:0013419
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare defect resulting in C1 deficiency and impaired activation of the complement classical pathway. C1 deficiency generally leads to severe immune complex disease with features of systemic lupus erythematosus and glomerulonephritis.","definition_xrefs":["PMID:11390518"],"direct_ancestors":[{"relation_name":"is_a","term_name":"classic complement early component deficiency","termid":"MONDO:0000015"},{"relation_name":"is_a","term_name":"immunodeficiency due to a classical component pathway complement deficiency","termid":"MONDO:0015699"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"complement component C1s deficiency","secondary_identifiers":["NANDO:2200779","OMIM:613783","UMLS:C3151078","MESH:C565170","MEDGEN:462428","GARD:15707"],"synonyms":[{"name":"C1SD","type":"related"},{"name":"C1s deficiency","type":"related"},{"name":"complement component C1s deficiency","type":"exact"}],"termid":"MONDO:0013419","xrefs":{"Monarch":{"xref_id":"0013419"}}}


id: PBO:0060606
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nuclear cap binding protein subunit 2","termid":"PBO:0060606"}


id: SO:0000123
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"An attribute describing a gene that is regulated at transcription.","definition_xrefs":["SO:ma"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulated","termid":"SO:0000119"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcriptionally_regulated","synonyms":[{"name":"transcriptionally regulated","type":"exact"}],"termid":"SO:0000123"}


id: PBO:0045933
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"elongation factor like GTPase 1","termid":"PBO:0045933"}


id: GO:0036273
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a statin stimulus. Statins are organooxygen compounds whose structure is related to compactin (mevastatin) and which may be used as an anticholesteremic drug due its EC:1.1.1.34/EC:1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitory properties.","definition_xrefs":["GOC:hp"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to oxygen-containing compound","termid":"GO:1901700"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to statin","synonyms":[{"name":"response to HMG-CoA reductase inhibitor","type":"related"},{"name":"response to hydroxymethylglutaryl-CoA reductase inhibitor","type":"related"}],"termid":"GO:0036273"}


id: GO:1900404
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of DNA repair.","definition_xrefs":["PMID:20299455","GOC:TermGenie","GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter (obsolete GO:1900404)","synonyms":[{"name":"activation of DNA repair by positive regulation of transcription from RNA polymerase II promoter","type":"narrow"},{"name":"stimulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter","type":"narrow"},{"name":"up regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"up-regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"upregulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter","type":"exact"}],"termid":"GO:1900404"}


id: PBO:0001861
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3.4.17.4","termid":"PBO:0001861"}


id: MONDO:0013327
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Primary hyperoxaluria type 3 (PH3) is a disorder of glyoxylate metabolism that can be asymptomatic or characterized by oxalate nephrolithiasis.","definition_xrefs":["Orphanet:93600"],"direct_ancestors":[{"relation_name":"is_a","term_name":"primary hyperoxaluria","termid":"MONDO:0002474"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0037792"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0037792"],"is_obsolete":false,"name":"primary hyperoxaluria type 3","secondary_identifiers":["GARD:10738","NCIT:C123214","MEDGEN:462228","SCTID:734990008","UMLS:C3150878","OMIM:613616","DOID:0111672"],"synonyms":[{"name":"HOGA1 primary hyperoxaluria","type":"exact"},{"name":"HP3","type":"related"},{"name":"PH III","type":"related"},{"name":"hyperoxaluria, primary, type 3","type":"related"},{"name":"hyperoxaluria, primary, type III","type":"related"},{"name":"primary hyperoxaluria caused by mutation in HOGA1","type":"exact"},{"name":"primary hyperoxaluria type III","type":"exact"}],"termid":"MONDO:0013327","xrefs":{"Monarch":{"xref_id":"0013327"}}}


id: GO:0045773
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of axon extension.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cell growth","termid":"GO:0030307"},{"relation_name":"is_a","term_name":"regulation of axon extension","termid":"GO:0030516"},{"relation_name":"is_a","term_name":"positive regulation of developmental growth","termid":"GO:0048639"},{"relation_name":"is_a","term_name":"positive regulation of axonogenesis","termid":"GO:0050772"},{"relation_name":"positively_regulates","term_name":"axon extension","termid":"GO:0048675"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of axon extension","synonyms":[{"name":"activation of axon extension","type":"narrow"},{"name":"stimulation of axon extension","type":"narrow"},{"name":"up regulation of axon extension","type":"exact"},{"name":"up-regulation of axon extension","type":"exact"},{"name":"upregulation of axon extension","type":"exact"}],"termid":"GO:0045773"}


id: GO:0140363
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A ribonucleoprotein granule located in the cytoplasm that is formed by the RNA-binding protein TIS11B and RNA molecules, enriched in membrane protein-encoding mRNAs with multiple AU-rich elements. TIS granules are reticular meshworks intertwined with the endoplasmic reticulum (ER).","definition_xrefs":["Wikipedia:TIGER_domain","PMID:30449617","PMID:30479375"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytoplasmic ribonucleoprotein granule","termid":"GO:0036464"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005737","GO:0005575"],"is_obsolete":false,"name":"TIS granule","termid":"GO:0140363"}


id: FYPO:0006733
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which movement of the CMG complex away from replication origins during DNA replication is normal.","definition_xrefs":["PMID:22718908","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal cellular process during vegetative growth","termid":"FYPO:0001319"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001312"}],"interesting_parent_ids":["FYPO:0001312","FYPO:0001320","FYPO:0000002","FYPO:0000257"],"is_obsolete":false,"name":"normal CMG complex progression from replication origin","synonyms":[{"name":"normal CMG complex translocation from replication origin","type":"exact"},{"name":"normal replicative helicase progression from replication origin","type":"exact"}],"termid":"FYPO:0006733"}


id: FYPO:0003781
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of all or part of the nuclear envelope is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal nuclear envelope morphology","termid":"FYPO:0003751"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"normal nuclear envelope morphology during mitotic interphase","synonyms":[{"name":"normal nuclear envelope morphology during interphase during vegetative growth","type":"exact"},{"name":"normal nuclear envelope morphology during interphase of mitotic cell cycle","type":"exact"},{"name":"normal nuclear membrane morphology during mitotic interphase","type":"narrow"}],"termid":"FYPO:0003781"}


id: PBO:0085136
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Nucleolar protein required for export of tRNAs from the nucleus; also copurifies with the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA","termid":"PBO:0085136"}


id: MONDO:0005946
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Chronic, localized granulomatous infection of mucocutaneous tissues, especially the nose, and characterized by hyperplasia and the development of polyps. It is found in humans and other animals and is caused by the mesomycetozoean organism rhinosporidium seeberi.","definition_xrefs":["MESH:D012227"],"direct_ancestors":[{"relation_name":"is_a","term_name":"parasitic Ichthyosporea infectious disease","termid":"MONDO:0000307"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"rhinosporidiosis","secondary_identifiers":["EFO:0007471","MEDGEN:48452","UMLS:C0035469","ICD9:117.0","DOID:2409","SCTID:18140003","ICD10CM:B48.1","icd11.foundation:1150206155"],"synonyms":[{"name":"Rhinosporidioses","type":"related"},{"name":"Rhinosporidium seeberi caused disease or disorder","type":"exact"},{"name":"Rhinosporidium seeberi disease or disorder","type":"exact"},{"name":"Rhinosporidium seeberi infectious disease","type":"exact"},{"name":"infection by Rhinosporidium seeberi","type":"exact"}],"termid":"MONDO:0005946","xrefs":{"Monarch":{"xref_id":"0005946"}}}


id: PBO:0079845
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"unc-13 homolog D","termid":"PBO:0079845"}


id: PR:Q10086
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- toe4 gene.","definition_xrefs":["UniProtKB:Q10086","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized transcriptional regulatory protein C11D3.07c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC11D3.07c","synonyms":[{"name":"Spom972h-toe4","type":"exact"}],"termid":"PR:Q10086"}


id: PBO:0040267
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"atlastin GTPase 2","termid":"PBO:0040267"}


id: PBO:0001223
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial glutamyl-tRNA synthetase Mse1 (predicted)","termid":"PBO:0001223"}


id: PBO:0083140
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; almost completely overlaps 3' end of ORF FKS3/YMR306W","termid":"PBO:0083140"}


id: PBO:0073917
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SLC16A6 pseudogene 1","termid":"PBO:0073917"}


id: PBO:0068946
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 190, pseudogene","termid":"PBO:0068946"}


id: GO:0140008
data:
  {"annotated_genes":["SJAG_00545","SJAG_02701","SJAG_01205"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[100721],"is_not":false,"summary":null,"term":"GO:0140008"},{"annotations":[109764,111168],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140005"},{"annotations":[109765],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990889"}]},"cv_name":"molecular_function","definition":"A histone reader that specifically binds either to an unmodified histone H4 or a form modified by a post-translational modification on a specific residue. The most common PTMs on histones are methylation, acetylation and phosphorylation.","definition_xrefs":["PMID:25688442","PMID:31082667","PMID:34726351","PMID:11498575"],"direct_ancestors":[{"relation_name":"is_a","term_name":"histone reader activity","termid":"GO:0140566"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00545":null,"SJAG_01205":null,"SJAG_02701":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0030674"},{"rel_name":"is_a","termid":"GO:0060090"},{"rel_name":"is_a","termid":"GO:0140566"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0030674","GO:0003674","GO:0140566","GO:0060090"],"is_obsolete":false,"name":"histone H4 reader activity","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0140008","terms_by_termid":{"GO:0140005":null,"GO:0140008":null,"GO:1990889":null}}


id: PBO:0082721
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of the Paf1p complex involved in transcription elongation; binds to and modulates the activity of RNA polymerases I and II; required for expression of a subset of genes, including cyclin genes; involved in SER3 repression by helping to maintain SRG1 transcription-dependent nucleosome occupancy; contains TPR repeats","termid":"PBO:0082721"}


id: PR:P24339
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- cut7 gene.","definition_xrefs":["PRO:DNx","UniProtKB:P24339"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kinesin-like protein cut7 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC25G10.07c","synonyms":[{"name":"Spom972h-cut7","type":"exact"},{"name":"cell untimely torn protein 7 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:P24339"}


id: PBO:0078274
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Cys (anticodon GCA) 9-2","termid":"PBO:0078274"}


id: MONDO:0018721
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete rare combined vascular malformation (obsolete MONDO:0018721)","secondary_identifiers":["Orphanet:458837"],"termid":"MONDO:0018721","xrefs":{"Monarch":{"xref_id":"0018721"}}}


id: PBO:0083251
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; identified by homology to a hemiascomycetous yeast protein","termid":"PBO:0083251"}


id: GO:1904327
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a protein is transported to, or maintained in, a location within a cytosolic proteasome complex.","definition_xrefs":["GOC:TermGenie","PMID:17000876","GOC:bf","GO_REF:0000087","GOC:PARL"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracellular protein localization","termid":"GO:0008104"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0051179","GO:0008150"],"is_obsolete":false,"name":"protein localization to cytosolic proteasome complex","synonyms":[{"name":"protein localisation in cytosolic proteasome complex","type":"exact"},{"name":"protein localisation to cytosolic proteasome complex","type":"exact"},{"name":"protein localization in cytosolic proteasome complex","type":"exact"}],"termid":"GO:1904327"}


id: PR:O42893
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- ntp1 gene.","definition_xrefs":["UniProtKB:O42893","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"neutral trehalase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC660.07","synonyms":[{"name":"Spom972h-ntp1","type":"exact"},{"name":"alpha,alpha-trehalase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"alpha,alpha-trehalose glucohydrolase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O42893"}


id: PBO:0053711
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 920","termid":"PBO:0053711"}


id: FYPO:0004946
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to one or more potassium ionophores. A potassium ionophore is any compound that can carry potassium ions through membranes of cells or organelles.","definition_xrefs":["CHEBI:24869","PMID:25483891","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased sensitivity to chemical during vegetative growth","termid":"FYPO:0000127"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002683"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000139","FYPO:0002683","FYPO:0000003","FYPO:0001985"],"is_obsolete":false,"name":"sensitive to potassium ionophore","synonyms":[{"name":"hypersensitive to potassium ionophore","type":"exact"},{"name":"sensitive to potassium ionophore during mitotic cell cycle","type":"related"},{"name":"sensitive to potassium ionophore during vegetative growth","type":"exact"}],"termid":"FYPO:0004946"}


id: GO:1904230
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of succinate dehydrogenase activity.","definition_xrefs":["PMID:18160053","GOC:BHF","GOC:rl","GO_REF:0000059","GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of succinate dehydrogenase activity (obsolete GO:1904230)","synonyms":[{"name":"down regulation of fumarate dehydrogenase activity","type":"exact"},{"name":"down regulation of fumarate reductase activity","type":"exact"},{"name":"down regulation of fumaric hydrogenase activity","type":"exact"},{"name":"down regulation of succinate dehydrogenase activity","type":"exact"},{"name":"down regulation of succinate oxidoreductase activity","type":"exact"},{"name":"down regulation of succinate:(acceptor) oxidoreductase activity","type":"exact"},{"name":"down regulation of succinate:acceptor oxidoreductase activity","type":"exact"},{"name":"down regulation of succinic acid dehydrogenase activity","type":"exact"},{"name":"down regulation of succinodehydrogenase activity","type":"exact"},{"name":"down regulation of succinyl dehydrogenase activity","type":"exact"},{"name":"down-regulation of fumarate dehydrogenase activity","type":"exact"},{"name":"down-regulation of fumarate reductase activity","type":"exact"},{"name":"down-regulation of fumaric hydrogenase activity","type":"exact"},{"name":"down-regulation of succinate dehydrogenase activity","type":"exact"},{"name":"down-regulation of succinate oxidoreductase activity","type":"exact"},{"name":"down-regulation of succinate:(acceptor) oxidoreductase activity","type":"exact"},{"name":"down-regulation of succinate:acceptor oxidoreductase activity","type":"exact"},{"name":"down-regulation of succinic acid dehydrogenase activity","type":"exact"},{"name":"down-regulation of succinodehydrogenase activity","type":"exact"},{"name":"down-regulation of succinyl dehydrogenase activity","type":"exact"},{"name":"downregulation of fumarate dehydrogenase activity","type":"exact"},{"name":"downregulation of fumarate reductase activity","type":"exact"},{"name":"downregulation of fumaric hydrogenase activity","type":"exact"},{"name":"downregulation of succinate dehydrogenase activity","type":"exact"},{"name":"downregulation of succinate oxidoreductase activity","type":"exact"},{"name":"downregulation of succinate:(acceptor) oxidoreductase activity","type":"exact"},{"name":"downregulation of succinate:acceptor oxidoreductase activity","type":"exact"},{"name":"downregulation of succinic acid dehydrogenase activity","type":"exact"},{"name":"downregulation of succinodehydrogenase activity","type":"exact"},{"name":"downregulation of succinyl dehydrogenase activity","type":"exact"},{"name":"inhibition of fumarate dehydrogenase activity","type":"narrow"},{"name":"inhibition of fumarate reductase activity","type":"narrow"},{"name":"inhibition of fumaric hydrogenase activity","type":"narrow"},{"name":"inhibition of succinate dehydrogenase activity","type":"narrow"},{"name":"inhibition of succinate oxidoreductase activity","type":"narrow"},{"name":"inhibition of succinate:(acceptor) oxidoreductase activity","type":"narrow"},{"name":"inhibition of succinate:acceptor oxidoreductase activity","type":"narrow"},{"name":"inhibition of succinic acid dehydrogenase activity","type":"narrow"},{"name":"inhibition of succinodehydrogenase activity","type":"narrow"},{"name":"inhibition of succinyl dehydrogenase activity","type":"narrow"},{"name":"negative regulation of fumarate dehydrogenase activity","type":"exact"},{"name":"negative regulation of fumarate reductase activity","type":"exact"},{"name":"negative regulation of fumaric hydrogenase activity","type":"exact"},{"name":"negative regulation of succinate oxidoreductase activity","type":"exact"},{"name":"negative regulation of succinate:(acceptor) oxidoreductase activity","type":"exact"},{"name":"negative regulation of succinate:acceptor oxidoreductase activity","type":"exact"},{"name":"negative regulation of succinic acid dehydrogenase activity","type":"exact"},{"name":"negative regulation of succinodehydrogenase activity","type":"exact"},{"name":"negative regulation of succinyl dehydrogenase activity","type":"exact"}],"termid":"GO:1904230"}


id: MONDO:0010185
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A form of methylmalonic acidemia with homocystinuria, an inborn error of vitamin B12 (cobalamin) metabolism characterized by variable biochemical, neurological and hematological manifestations.","definition_xrefs":["Orphanet:79283"],"direct_ancestors":[{"relation_name":"is_a","term_name":"methylmalonic aciduria and homocystinuria","termid":"MONDO:0016826"},{"relation_name":"is_a","term_name":"methylmalonic aciduria and/or homocystinuria, cblD type","termid":"MONDO:0100463"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002280"},{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004736"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0002280","MONDO:0005570","MONDO:0004736"],"is_obsolete":false,"name":"methylmalonic aciduria and homocystinuria type cblD","secondary_identifiers":["UMLS:C1848552","MESH:C564743","NANDO:2201108","SCTID:31220004","MEDGEN:341253","OMIM:277410","GARD:3582","DOID:0050716","NANDO:1200797"],"synonyms":[{"name":"MAHCD","type":"related"},{"name":"cblD - cobalamin locus d","type":"related"},{"name":"cblD defect","type":"exact"},{"name":"cblD methylmalonic acidemia and homocystinuria","type":"related"},{"name":"cobalamin D defect","type":"exact"},{"name":"cobalamin D deficiency","type":"exact"},{"name":"cobalamin d disease","type":"exact"},{"name":"combined defect in adenosylcobalamin and methylcobalamin synthesis, type cblD","type":"exact"},{"name":"homocystinuria, cblD type, variant 1","type":"related"},{"name":"homocystinuria, cblD type, variant 1, included","type":"related"},{"name":"m0e.321 cobalamin locus d variant","type":"related"},{"name":"mehtylmalonic acidemia with homocystinuria cbI d","type":"related"},{"name":"methylmalonic acidemia and homocystinuria, cblD type","type":"related"},{"name":"methylmalonic acidemia with homocystinuria type cblD","type":"related"},{"name":"methylmalonic acidemia with homocystinuria, type cblD","type":"related"},{"name":"methylmalonic acidemia, Cblh type","type":"related"},{"name":"methylmalonic acidemia, Cblh type, formerly","type":"related"},{"name":"methylmalonic aciduria and homocystinuria type cblD","type":"exact"},{"name":"methylmalonic aciduria and homocystinuria, cblD type","type":"related"},{"name":"methylmalonic aciduria with homocystinuria, type cblD","type":"exact"},{"name":"methylmalonic aciduria, Cblh type","type":"related"},{"name":"methylmalonic aciduria, Cblh type, formerly","type":"related"},{"name":"methylmalonic aciduria, cblD type, variant 2","type":"related"},{"name":"methylmalonic aciduria, cblD type, variant 2, included","type":"related"}],"termid":"MONDO:0010185","xrefs":{"Monarch":{"xref_id":"0010185"}}}


id: PBO:0000308
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"C-4 methylsterol oxidase (predicted)","termid":"PBO:0000308"}


id: MONDO:1012820
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Congenital hypotrichosis that occurs in sheep due to a mutation in the HR gene.","definition_xrefs":["MONDO:patterns/nonhuman_disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"congenital hypotrichosis, non-human animal","termid":"MONDO:1012977"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hypotrichosis, HR-related, sheep","secondary_identifiers":["OMIA:002229-9940"],"termid":"MONDO:1012820","xrefs":{"Monarch":{"xref_id":"1012820"}}}


id: PBO:0052112
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"potassium voltage-gated channel subfamily B member 2","termid":"PBO:0052112"}


id: PBO:0075830
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"signal sequence receptor subunit 4 pseudogene 1","termid":"PBO:0075830"}


id: PBO:0044228
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cubilin pseudogene 2","termid":"PBO:0044228"}


id: PBO:0043103
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"carbohydrate sulfotransferase 15","termid":"PBO:0043103"}


id: PBO:0004065
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA snR33","termid":"PBO:0004065"}


id: MONDO:0017335
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Microtriplication 11q24.1 is an extremely rare partial autosomal tetrasomy, resulting from a partial triplication of the long arm of chromosome 11, characterized by intellectual disability (with severe verbal impairment), short stature with small extremities, keratoconus and distinctive facial features (round, course face, upward slanting palpebral fissures, mild synophris, large nose with thick ala nasi and triangular tip, large mouth with broad lips, short and smooth philtrum, large protruded chin, ears with adherent lobules). Additionally, patients are overweight and present hypercholesterolemia.","definition_xrefs":["Orphanet:289522"],"direct_ancestors":[{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"},{"relation_name":"is_a","term_name":"chromosome 11q trisomy","termid":"MONDO:0022173"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microtriplication 11q24.1","secondary_identifiers":["MEDGEN:1656562","GARD:21142","UMLS:C4749373"],"synonyms":[{"name":"tetrasomy 11q24.1","type":"exact"}],"termid":"MONDO:0017335","xrefs":{"Monarch":{"xref_id":"0017335"}}}


id: PBO:0060224
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"matrix remodeling associated 5 Y-linked (pseudogene)","termid":"PBO:0060224"}


id: PATO:0001125
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0001125 absolute pressure value (obsolete PATO:0001125)","termid":"PATO:0001125"}


id: MONDO:0001375
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A malignant neoplasm involving the trigone of urinary bladder.","direct_ancestors":[{"relation_name":"is_a","term_name":"bladder dome cancer","termid":"MONDO:0001380"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"bladder trigone cancer","secondary_identifiers":["SCTID:188239000","MEDGEN:635606","DOID:11813","UMLS:C0496826","ICD9:188.0"],"synonyms":[{"name":"cancer of trigone of urinary bladder","type":"exact"},{"name":"malignant neoplasm of trigone of urinary bladder","type":"exact"},{"name":"malignant trigone of urinary bladder neoplasm","type":"exact"},{"name":"trigone of urinary bladder cancer","type":"exact"}],"termid":"MONDO:0001375","xrefs":{"Monarch":{"xref_id":"0001375"}}}


id: SO:0001613
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A sequence variant with in the CDS that causes out of frame elongation of the resulting polypeptide sequence at the C terminus.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"elongated_polypeptide_C_terminal","termid":"SO:0001610"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"elongated_out_of_frame_polypeptide_C_terminal","synonyms":[{"name":"elongated polypeptide out of frame C terminal","type":"exact"}],"termid":"SO:0001613"}


id: PR:Q9HDY5
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAPB1A10.05 gene.","definition_xrefs":["UniProtKB:Q9HDY5","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein PB1A10.05 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAPB1A10.05","synonyms":[{"name":"Spom972h-SPAPB1A10.05","type":"exact"}],"termid":"PR:Q9HDY5"}


id: GO:0002759
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of an antimicrobial humoral response.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of response to biotic stimulus","termid":"GO:0002831"},{"relation_name":"is_a","term_name":"regulation of humoral immune response","termid":"GO:0002920"},{"relation_name":"is_a","term_name":"regulation of defense response","termid":"GO:0031347"},{"relation_name":"is_a","term_name":"regulation of response to external stimulus","termid":"GO:0032101"},{"relation_name":"regulates","term_name":"antimicrobial humoral response","termid":"GO:0019730"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of antimicrobial humoral response","termid":"GO:0002759"}


id: MONDO:1010465
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Patent ductus arteriosus that occurs in dog.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"patent ductus arteriosus, non-human animal","termid":"MONDO:1010017"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"patent ductus arteriosus, dog","secondary_identifiers":["OMIA:000779-9615"],"termid":"MONDO:1010465","xrefs":{"Monarch":{"xref_id":"1010465"}}}


id: PBO:0045922
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"EF-hand calcium binding domain 14 pseudogene 1","termid":"PBO:0045922"}


id: GO:0071278
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to cesium ion","termid":"GO:0010164"},{"relation_name":"is_a","term_name":"cellular response to metal ion","termid":"GO:0071248"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to cesium ion","synonyms":[{"name":"cellular response to cesium","type":"exact"}],"termid":"GO:0071278"}


id: GO:0014012
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The regrowth of axons outside the central nervous system (outside the brain and spinal cord) following an axonal injury.","definition_xrefs":["GOC:ef"],"direct_ancestors":[{"relation_name":"is_a","term_name":"axon regeneration","termid":"GO:0031103"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"peripheral nervous system axon regeneration","synonyms":[{"name":"axon regeneration in peripheral nervous system","type":"exact"}],"termid":"GO:0014012"}


id: PBO:0060496
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nucleosome assembly protein 1 like 1 pseudogene 1","termid":"PBO:0060496"}


id: PBO:0067439
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 560, pseudogene","termid":"PBO:0067439"}


id: MONDO:0005094
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An antiquated term that refers to benign or malignant mesenchymal neoplasms characterized by the presence of neoplastic spindle-shaped to round cells arranged around thin-walled branching vascular spaces.","definition_xrefs":["NCIT:C3087"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete connective tissue cancer (obsolete MONDO:0002176)","termid":"MONDO:0002176"},{"relation_name":"is_a","term_name":"hemangiopericytic tumor","termid":"MONDO:0002789"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hemangiopericytoma","secondary_identifiers":["MESH:D006393","DOID:264","SCTID:134335004","UMLS:C0018922","ICDO:9150/1","MEDGEN:5478"],"synonyms":[{"name":"haemangiopericytic meningioma","type":"exact"},{"name":"haemangiopericytic meningioma [obs]","type":"exact"},{"name":"hemangiopericytoma","type":"exact"},{"name":"hemangiopericytoma, malignant (morphologic abnormality)","type":"narrow"},{"name":"malignant hemangiopericytoma","type":"narrow"}],"termid":"MONDO:0005094","xrefs":{"Monarch":{"xref_id":"0005094"}}}


id: PBO:0078712
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Leu (anticodon CAG) 1-7","termid":"PBO:0078712"}


id: MONDO:0000575
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete MONDO:0000575 (obsolete MONDO:0000575)","termid":"MONDO:0000575","xrefs":{"Monarch":{"xref_id":"0000575"}}}


id: MONDO:0014298
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"PDE4D haploinsufficiency syndrome is a rare syndromic intellectual disability characterized by developmental delay, intellectual disability, low body mass index, long arms, fingers and toes, prominent nose and small chin.","definition_xrefs":["Orphanet:439822"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"},{"relation_name":"is_a","term_name":"partial deletion of the long arm of chromosome 5","termid":"MONDO:0016904"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 5q12 deletion syndrome","secondary_identifiers":["GARD:17742","MEDGEN:816612","OMIM:615668","UMLS:C3810282","DOID:0060421"],"synonyms":[{"name":"PDE4D haploinsufficiency syndrome","type":"related"},{"name":"chromosome 5q12 deletion syndrome","type":"exact"}],"termid":"MONDO:0014298","xrefs":{"Monarch":{"xref_id":"0014298"}}}


id: PBO:0052469
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"KLF transcription factor 15","termid":"PBO:0052469"}


id: PBO:0082484
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cargo-transport protein involved in endocytosis; interacts with phosphatidylinositol-4-kinase Stt4p; is required, along with Efr3p, for the assembly and recruitment of multiple copies of the kinase into phosphoinositide kinase (PIK) patches at the plasma membrane; positively regulates Stt4p; GFP-fusion protein localizes to the cytoplasm; YGR198W is an essential gene","termid":"PBO:0082484"}


id: GO:0055035
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The lipid bilayer membrane of any thylakoid within a plastid.","definition_xrefs":["GOC:jid","GOC:rph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plastid membrane","termid":"GO:0042170"},{"relation_name":"is_a","term_name":"thylakoid membrane","termid":"GO:0042651"},{"relation_name":"part_of","term_name":"plastid thylakoid","termid":"GO:0031976"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005737","GO:0005575"],"is_obsolete":false,"name":"plastid thylakoid membrane","termid":"GO:0055035"}


id: PBO:0113033
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cell-wall L-asparaginase II involved in asparagine catabolism; expression induced during nitrogen starvation; ORF contains a short non-coding RNA that enhances expression of full-length gene; likely arose in via horizontal gene transfer from the wine yeast Wickerhamomyces anomalus or a close relative; enzyme preparation shows antitumor activity; reference strain S288C has four copies of ASP3; ASP3-3 has a paralog, ASP3-1, that arose from a segmental duplication","termid":"PBO:0113033"}


id: MONDO:0009113
data:
  {"annotated_genes":["SJAG_02009"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88881],"is_not":false,"summary":null,"term":"MONDO:0009113"}]},"cv_name":"mondo","definition":"A rare, autosomal recessive, inherited disorder caused by mutation of the BPGM gene. It is characterized by hemolytic anemia and splenomegaly.","definition_xrefs":["NCIT:C131638"],"direct_ancestors":[{"relation_name":"is_a","term_name":"familial hemolytic anemia","termid":"MONDO:0003689"},{"relation_name":"is_a","term_name":"inborn errors of metabolism","termid":"MONDO:0019052"},{"relation_name":"is_a","term_name":"anemia due to erythrocyte enzyme disorder","termid":"MONDO:0020585"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02009":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0002280"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0005066","MONDO:0002280"],"is_obsolete":false,"name":"hemolytic anemia due to diphosphoglycerate mutase deficiency","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["DOID:0111630","GARD:1874","MEDGEN:489898","OMIM:222800","Orphanet:714","UMLS:C1291620"],"synonyms":[{"name":"BPGM deficiency","type":"related"},{"name":"DPGM deficiency","type":"related"},{"name":"bisphosphoglycerate mutase deficiency","type":"related"},{"name":"bisphosphoglyceromutase deficiency","type":"related"},{"name":"diphosphoglycerate mutase deficiency of erythrocyte","type":"related"},{"name":"diphosphoglycerate phosphatase deficiency","type":"exact"},{"name":"erythrocytosis, familial, 8","type":"exact"}],"termid":"MONDO:0009113","terms_by_termid":{"MONDO:0009113":null},"xrefs":{"Monarch":{"xref_id":"0009113"}}}


id: MONDO:0014767
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any Seckel syndrome in which the cause of the disease is a mutation in the TRAIP gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Seckel syndrome","termid":"MONDO:0019342"},{"relation_name":"is_a","term_name":"primordial dwarfism and slender bone disorder","termid":"MONDO:0800063"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0006025"],"is_obsolete":false,"name":"Seckel syndrome 9","secondary_identifiers":["UMLS:C4225212","MEDGEN:907155","DOID:0070005","OMIM:616777","GARD:16158"],"synonyms":[{"name":"SCKL9","type":"exact"},{"name":"Seckel syndrome 9","type":"exact"},{"name":"Seckel syndrome caused by mutation in TRAIP","type":"exact"},{"name":"Seckel syndrome type 9","type":"exact"},{"name":"TRAIP Seckel syndrome","type":"exact"}],"termid":"MONDO:0014767","xrefs":{"Monarch":{"xref_id":"0014767"}}}


id: PATO:0000380
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A frequency which is relatively high.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"increased_in_magnitude_relative_to","term_name":"normal","termid":"PATO:0000461"},{"relation_name":"is_a","term_name":"frequency","termid":"PATO:0000044"},{"relation_name":"is_a","term_name":"increased rate","termid":"PATO:0000912"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"increased frequency","synonyms":[{"name":"frequent","type":"related"},{"name":"high frequency","type":"exact"}],"termid":"PATO:0000380"}


id: GO:0052183
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process in which a host organism destabilizes a cellular component of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"gene_count":0,"genotype_count":0,"name":"obsolete disruption of symbiont cellular component (obsolete GO:0052183)","synonyms":[{"name":"degradation of symbiont cellular component by organism","type":"related"},{"name":"disassembly by host of symbiont cellular component","type":"narrow"},{"name":"disruption by host of symbiont cellular component","type":"related"},{"name":"disruption by host of symbiont structure","type":"exact"},{"name":"modification by host of symbiont cellular component","type":"exact"},{"name":"modification by host of symbiont structure","type":"broad"},{"name":"perturbation of symbiont cellular component","type":"exact"}],"termid":"GO:0052183"}


id: GO:0043420
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving anthranilate (2-aminobenzoate).","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"aromatic amino acid metabolic process","termid":"GO:0009072"},{"relation_name":"is_a","term_name":"monocarboxylic acid metabolic process","termid":"GO:0032787"},{"relation_name":"is_a","term_name":"benzene-containing compound metabolic process","termid":"GO:0042537"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0006520"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0006520"],"is_obsolete":false,"name":"anthranilate metabolic process","secondary_identifiers":["UM-BBD_pathwayID:abz2","GO:0018869"],"synonyms":[{"name":"2-aminobenzoate metabolic process","type":"exact"},{"name":"2-aminobenzoate metabolism","type":"exact"},{"name":"anthranilate metabolism","type":"exact"},{"name":"anthranilic acid metabolic process","type":"narrow"},{"name":"anthranilic acid metabolism","type":"narrow"},{"name":"ortho-aminobenzoic acid metabolic process","type":"narrow"},{"name":"ortho-aminobenzoic acid metabolism","type":"narrow"}],"termid":"GO:0043420"}


id: FYPO:0001502
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is higher than normal during a cellular response to osmotic stress.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased cellular trehalose level during vegetative growth","termid":"FYPO:0001444"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"increased cellular trehalose level during cellular response to osmotic stress","synonyms":[{"name":"increased cellular trehalose level during cellular response to osmotic stress during mitotic cell cycle","type":"related"},{"name":"increased cellular trehalose level during vegetative growth and during cellular response to osmotic stress","type":"exact"},{"name":"increased cellular trehalose level in response to osmotic stress","type":"exact"},{"name":"increased trehalose accumulation during cellular response to osmotic stress","type":"related"}],"termid":"FYPO:0001502"}


id: PBO:0045355
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dolichyl-phosphate N-acetylglucosaminephosphotransferase 1","termid":"PBO:0045355"}


id: MONDO:0012761
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"3q29 microduplication is a chromosomal abnormality associated with variable clinical findings including mild or moderate intellectual deficit and microcephaly.","definition_xrefs":["PMID:18241066"],"direct_ancestors":[{"relation_name":"is_a","term_name":"partial duplication of the long arm of chromosome 3","termid":"MONDO:0016954"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 3q29 microduplication syndrome","secondary_identifiers":["DECIPHER:77","Orphanet:251038","SCTID:717973004","MESH:C567626","GARD:10360","OMIM:611936","UMLS:C2749873","DOID:0060459","MEDGEN:440897"],"synonyms":[{"name":"3q29 microduplication","type":"exact"},{"name":"3q29 microduplication syndrome","type":"exact"},{"name":"chromosome 3q29 DUPLICATION syndrome","type":"related"},{"name":"microduplication 3Q29 syndrome","type":"related"},{"name":"trisomy 3q29","type":"exact"}],"termid":"MONDO:0012761","xrefs":{"Monarch":{"xref_id":"0012761"}}}


id: PBO:0042981
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromodomain helicase DNA binding protein 7","termid":"PBO:0042981"}


id: PBO:0036221
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_arginase_activity","termid":"PBO:0036221"}


id: PBO:0082192
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Aldehyde reductase; substrates include both aromatic and aliphatic aldehydes; uses NADPH as cofactor; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and vacuole respectively","termid":"PBO:0082192"}


id: PBO:0088788
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP-dependent RNA helicase Rok1","termid":"PBO:0088788"}


id: PBO:0040359
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP synthase membrane subunit g pseudogene 8","termid":"PBO:0040359"}


id: PBO:0113122
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Essential ATP-binding protein required for DNA replication; component of the pre-replicative complex (pre-RC) which requires ORC to associate with chromatin and is in turn required for Mcm2-7p DNA association; dual role as a mitotic cyclin-dependent kinase inhibitor, that binds to and inhibits Cdc28p/Clb2p along with Sic1p, contributing to mitotic exit; homologous to S. pombe Cdc18p; relocalizes from nucleus to cytoplasm upon DNA replication stress; degraded in response to plasma membrane stress","termid":"PBO:0113122"}


id: PBO:0081322
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 112","termid":"PBO:0081322"}


id: GO:0008104
data:
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id: MONDO:0013915
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  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any hypogonadotropic hypogonadism in which the cause of the disease is a mutation in the KISS1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hypogonadotropic hypogonadism","termid":"MONDO:0018555"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hypogonadotropic hypogonadism 13 with or without anosmia","secondary_identifiers":["MEDGEN:762090","DOID:0090073","GARD:18601","ICD10CM:E23.0","OMIM:614842","UMLS:C3541462"],"synonyms":[{"name":"HH13","type":"related"},{"name":"KISS1 hypogonadotropic hypogonadism","type":"exact"},{"name":"hypogonadotropic hypogonadism 13 with or without anosmia","type":"exact"},{"name":"hypogonadotropic hypogonadism caused by mutation in KISS1","type":"exact"}],"termid":"MONDO:0013915","xrefs":{"Monarch":{"xref_id":"0013915"}}}


id: PBO:0036507
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"inositol polyphosphate kinase Kcs1 (predicted)","termid":"PBO:0036507"}


id: PBO:0041533
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 17 open reading frame 49","termid":"PBO:0041533"}


id: PBO:0113230
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADH-dependent short-chain aldehyde reductase; involved in detoxification of furfural; expression is upregulated in cells treated with the aldehydes furfural and glycolaldehyde, the mycotoxin patulin, and also the quinone methide triterpene celastrol; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm","termid":"PBO:0113230"}


id: PBO:0070503
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L6 pseudogene 2","termid":"PBO:0070503"}


id: MONDO:0008267
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Oral-facial-digital syndrome, type 5 is characterized by median cleft of the upper lip, postaxial polydactyly of hands and feet, and oral manifestations (duplicated frenulum).","definition_xrefs":["Orphanet:2919"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"is_a","term_name":"orofaciodigital syndrome","termid":"MONDO:0015375"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"orofaciodigital syndrome V","secondary_identifiers":["DOID:0060375","OMIM:174300","MEDGEN:358131","GARD:4120","MESH:C557819","SCTID:722105002","UMLS:C1868118"],"synonyms":[{"name":"OFD syndrome 5","type":"related"},{"name":"OFD5","type":"exact"},{"name":"Ofds 5","type":"related"},{"name":"Thurston syndrome","type":"exact"},{"name":"oral facial digital syndrome 5","type":"related"},{"name":"oral facial digital syndrome type 5","type":"related"},{"name":"oral-Facial-digital syndrome, type 5","type":"related"},{"name":"oral-facial-digital syndrome 5","type":"related"},{"name":"oral-facial-digital syndrome type 5","type":"exact"},{"name":"orofaciodigital syndrome 5","type":"related"},{"name":"orofaciodigital syndrome Thurston type","type":"exact"},{"name":"orofaciodigital syndrome V","type":"exact"},{"name":"orofaciodigital syndrome type 5","type":"exact"},{"name":"orofaciodigital syndrome type V","type":"exact"},{"name":"orofaciodigital syndrome, Thurston type","type":"exact"},{"name":"polydactyly postaxial with median cleft of upper lip","type":"exact"},{"name":"polydactyly, postaxial, with Median cleft of upper lip","type":"related"},{"name":"polydactyly, postaxial, with median cleft of upper lip","type":"exact"}],"termid":"MONDO:0008267","xrefs":{"Monarch":{"xref_id":"0008267"}}}


