# terms

id: GO:0043232
data:
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id: PBO:0050170
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id: PBO:0113273
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id: GO:0017061
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id: FYPO:0000526
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id: FYPO:0006647
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id: GO:0015447
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id: PBO:0076871
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id: GO:0102106
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id: GO:1900417
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id: PBO:0044095
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id: GO:0060476
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id: MONDO:0015459
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A carcinoma arising from the nasopharyngeal epithelium. It includes the following types: keratinizing squamous cell carcinoma, nonkeratinizing carcinoma (differentiated and undifferentiated), basaloid squamous cell carcinoma, and papillary adenocarcinoma.","definition_xrefs":["NCIT:C3871"],"direct_ancestors":[{"relation_name":"is_a","term_name":"head and neck carcinoma","termid":"MONDO:0002038"},{"relation_name":"is_a","term_name":"Epstein-Barr virus-associated carcinoma","termid":"MONDO:0017344"},{"relation_name":"is_a","term_name":"malignant tumor of nasopharynx","termid":"MONDO:0021315"},{"relation_name":"is_a","term_name":"carcinoma of pharynx","termid":"MONDO:0021345"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0004992"],"is_obsolete":false,"name":"nasopharyngeal carcinoma","secondary_identifiers":["ICD9:147","ICD9:147.0","ICD9:147.1","MESH:D000077274","MESH:C538339","GARD:7163","ICD9:147.2","ICD9:147.9","MESH:D00007727","UMLS:C2931822","ICD9:147.3","DOID:9261","icd11.foundation:1883313543","MedDRA:10028793","MEDGEN:419909","ONCOTREE:NPC","Orphanet:150","SCTID:363398003"],"synonyms":[{"name":"NPC","type":"exact"},{"name":"cancer of nasopharynx","type":"broad"},{"name":"cancer of the nasopharynx","type":"broad"},{"name":"carcinoma of nasopharynx","type":"exact"},{"name":"carcinoma of the nasopharynx","type":"exact"},{"name":"malignant nasopharyngeal tumor","type":"broad"},{"name":"malignant nasopharyngeal tumour","type":"broad"},{"name":"malignant neoplasm of anterior wall of nasopharynx","type":"broad"},{"name":"malignant neoplasm of lateral wall of nasopharynx","type":"broad"},{"name":"malignant neoplasm of nasopharyngeal wall","type":"broad"},{"name":"malignant neoplasm of nasopharynx","type":"broad"},{"name":"malignant neoplasm of nasopharynx (disorder) [ambiguous]","type":"broad"},{"name":"malignant neoplasm of other specified sites of nasopharynx","type":"broad"},{"name":"malignant neoplasm of posterior wall of nasopharynx","type":"broad"},{"name":"malignant neoplasm of roof of nasopharynx","type":"broad"},{"name":"malignant neoplasm of superior wall of nasopharynx","type":"broad"},{"name":"malignant tumor of anterior wall of nasopharynx","type":"broad"},{"name":"malignant tumor of lateral wall of nasopharynx","type":"broad"},{"name":"malignant tumor of posterior wall of nasopharynx","type":"broad"},{"name":"malignant tumour of anterior wall of nasopharynx","type":"broad"},{"name":"malignant tumour of lateral wall of nasopharynx","type":"broad"},{"name":"malignant tumour of posterior wall of nasopharynx","type":"broad"},{"name":"nasopharyngeal cancer","type":"broad"},{"name":"nasopharyngeal carcinoma","type":"exact"},{"name":"nasopharyngeal throat cancer","type":"broad"},{"name":"nasopharynx carcinoma","type":"exact"},{"name":"primary malignant neoplasm of anterior wall of nasopharynx","type":"broad"},{"name":"squamous cell carcinoma of the nasopharynx","type":"exact"}],"termid":"MONDO:0015459","xrefs":{"Monarch":{"xref_id":"0015459"}}}


id: PBO:0091018
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rab family GTPase Ryh1","termid":"PBO:0091018"}


id: PBO:0050336
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heterogeneous nuclear ribonucleoprotein A1pseudogene 38","termid":"PBO:0050336"}


id: PBO:0043489
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ciliary neurotrophic factor receptor","termid":"PBO:0043489"}


id: MONDO:0005252
data:
  {"annotated_genes":["SJAG_03866","SJAG_04757"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88428,88429],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009935"}]},"cv_name":"mondo","definition":"Inability of the heart to pump blood at an adequate rate to meet tissue metabolic requirements. Clinical symptoms of heart failure include: unusual dyspnea on light exertion, recurrent dyspnea occurring in the supine position, fluid retention or rales, jugular venous distension, pulmonary edema on physical exam, or pulmonary edema on chest x-ray presumed to be cardiac dysfunction.","definition_xrefs":["EFO:0003144"],"direct_ancestors":[{"relation_name":"is_a","term_name":"heart disorder","termid":"MONDO:0005267"}],"gene_count":2,"genes_by_uniquename":{"SJAG_03866":null,"SJAG_04757":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"heart failure","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MESH:D006333","NCIT:C50577","MEDGEN:6749","ICD10CM:I50","SCTID:84114007","icd11.foundation:1458683894","UMLS:C0018801","ICD9:428","ICD9:428.9"],"synonyms":[{"name":"cardiac failure","type":"exact"},{"name":"cardiac insufficiency","type":"exact"},{"name":"failure, heart","type":"exact"},{"name":"heart failure","type":"exact"},{"name":"insufficiency, Cardiac","type":"exact"}],"termid":"MONDO:0005252","terms_by_termid":{"MONDO:0009935":null},"xrefs":{"Monarch":{"xref_id":"0005252"}}}


id: PBO:0053829
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1094","termid":"PBO:0053829"}


id: PR:Q9UTK7
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- dsc2 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9UTK7"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DSC E3 ubiquitin ligase complex subunit 2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1486.02c","synonyms":[{"name":"Spom972h-dsc2","type":"exact"},{"name":"UBA domain-containing protein 14 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"defective for SREBP cleavage protein 2 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9UTK7"}


id: PBO:0067098
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 138, pseudogene","termid":"PBO:0067098"}


id: MONDO:0012382
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any hyperinsulinemic hypoglycemia in which the cause of the disease is a mutation in the HADH gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"3-hydroxyacyl-CoA dehydrogenase deficiency","termid":"MONDO:0017715"},{"relation_name":"is_a","term_name":"diazoxide-sensitive diffuse hyperinsulinism","termid":"MONDO:0015624"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0037792"}],"interesting_parent_ids":["MONDO:0037792","MONDO:0004335","MONDO:0005066"],"is_obsolete":false,"name":"hyperinsulinemic hypoglycemia, familial, 4","secondary_identifiers":["SCTID:721236002","MESH:C535310","DOID:0070215","GARD:9870","MESH:C566493","Orphanet:71212","MEDGEN:400646","OMIM:609975","UMLS:C1864948"],"synonyms":[{"name":"3-Alpha-hydroxyacyl-Coenzyme A dehydrogenase deficiency","type":"related"},{"name":"3-alpha hydroxyacyl-CoA dehydrogenase deficiency","type":"related"},{"name":"3-hydroxyacyl-CoA dehydrogenase deficiency","type":"related"},{"name":"3-hydroxyacyl-Coenzyme A dehydrogenase deficiency","type":"related"},{"name":"3-hydroxylacyl-CoA dehydrogenase deficiency","type":"related"},{"name":"HADH deficiency","type":"related"},{"name":"HADH hyperinsulinemic hypoglycemia (disease)","type":"exact"},{"name":"HADHSC deficiency","type":"related"},{"name":"HHF4","type":"related"},{"name":"L-3-Alpha-hydroxyacyl-CoA dehydrogenase, short chain, deficiency","type":"related"},{"name":"M-SCHAD deficiency","type":"related"},{"name":"M/SCHAD","type":"related"},{"name":"SCHAD deficiency","type":"related"},{"name":"SCHAD deficiency, formerly","type":"related"},{"name":"had deficiency","type":"related"},{"name":"hyperinsulinemic hypoglycemia (disease) caused by mutation in HADH","type":"exact"},{"name":"hyperinsulinemic hypoglycemia due to HADH deficiency","type":"exact"},{"name":"hyperinsulinemic hypoglycemia due to short chain 3-hydroxylacyl-CoA dehydrogenase deficiency","type":"exact"},{"name":"hyperinsulinemic hypoglycemia, familial, 4","type":"exact"},{"name":"hyperinsulinemic hypoglycemia, familial, type 4","type":"exact"},{"name":"hyperinsulinism due to SCHAD deficiency","type":"exact"},{"name":"hyperinsulinism due to glutamodehydrogenase deficiency","type":"exact"},{"name":"hyperinsulinism due to short chain 3-hydroxyacyl-coenzyme a dehydrogenase deficiency","type":"exact"},{"name":"hyperinsulinism due to short chain 3-hydroxylacyl-CoA dehydrogenase deficiency","type":"exact"},{"name":"medium and short chain 3-hydroxyacyl-CoA dehydrogenase deficiency","type":"related"}],"termid":"MONDO:0012382","xrefs":{"Monarch":{"xref_id":"0012382"}}}


id: PBO:0054050
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1392","termid":"PBO:0054050"}


id: GO:0043658
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A double-enveloped cell compartment, composed of the endosymbiont with its plasmalemma (as inner envelope) and an outer envelope (the perisymbiontic membrane) derived from the host cell.","definition_xrefs":["GOC:cc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"host intracellular membrane-bounded organelle","termid":"GO:0033648"},{"relation_name":"is_a","term_name":"host cell cytoplasm part","termid":"GO:0033655"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"host symbiosome","termid":"GO:0043658"}


id: GO:0141100
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: S-adenosyl-L-methionine + guanosine 18 in tRNA= S-adenosyl-L-homocysteine + 2'-O-methylguanosine 18 in tRNA + H+.","definition_xrefs":["PMID:25404562"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tRNA (guanine) methyltransferase activity","termid":"GO:0016423"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140101"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0016740","GO:0140101","GO:0003674","GO:0140098","GO:0016741"],"is_obsolete":false,"name":"tRNA (guanine(18)-2'-O)-methyltransferase activity","secondary_identifiers":["RHEA:20077","MetaCyc:2.1.1.34-RXN","EC:2.1.1.34"],"synonyms":[{"name":"tRNA (guanosine(18)-2'-O)-methyltransferase activity","type":"exact"}],"termid":"GO:0141100"}


id: GO:0008923
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-lysine + H+ = cadaverine + CO2.","definition_xrefs":["RHEA:22352"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxy-lyase activity","termid":"GO:0016831"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016829","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"lysine decarboxylase activity","secondary_identifiers":["EC:4.1.1.18","MetaCyc:LYSDECARBOX-RXN","KEGG_REACTION:R00462"],"synonyms":[{"name":"L-lysine carboxy-lyase activity","type":"related"}],"termid":"GO:0008923"}


id: FYPO:0001548
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell differs from normal during a cellular response to hydrogen peroxide. Total protein or a specific protein may be affected.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"altered protein level during vegetative growth","termid":"FYPO:0001325"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0001985","FYPO:0005447","FYPO:0006551","FYPO:0000002"],"is_obsolete":false,"name":"altered protein level during cellular response to hydrogen peroxide","synonyms":[{"name":"abnormal protein level during cellular response to hydrogen peroxide","type":"exact"},{"name":"altered cellular protein level during cellular response to hydrogen peroxide during vegetative growth","type":"exact"},{"name":"altered protein level during cellular response to H2O2","type":"exact"},{"name":"altered protein level during cellular response to hydrogen peroxide during mitotic cell cycle","type":"related"}],"termid":"FYPO:0001548"}


id: MOD:01127
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"OBSOLETE because redundant and identical to MOD:01166. Remap to MOD:01166.","definition_xrefs":["DeltaMass:292"],"gene_count":0,"genotype_count":0,"name":"OBSOLETE MOD:01127 5'phos Uridinyl (obsolete MOD:01127)","termid":"MOD:01127"}


id: FYPO:0002740
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which a cell proceeds normally through a specific mitotic cell cycle phase. A mitotic cell cycle phase is any of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.","definition_xrefs":["GO:0022403","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal mitotic cell cycle","termid":"FYPO:0000411"},{"relation_name":"is_a","term_name":"normal cell cycle phase","termid":"FYPO:0003833"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0001312","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"normal mitotic cell cycle phase","termid":"FYPO:0002740"}


id: PATO:0001339
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A composition quality inhering in an bearer by virtue of the bearer's homogeneity of a biomaterial.","definition_xrefs":["MGED:MGED"],"direct_ancestors":[{"relation_name":"is_a","term_name":"composition","termid":"PATO:0000025"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"biomaterial purity","termid":"PATO:0001339"}


id: FYPO:0001133
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which DNA replication is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal cellular process during vegetative growth","termid":"FYPO:0001319"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001312"}],"interesting_parent_ids":["FYPO:0001312","FYPO:0001320","FYPO:0000002","FYPO:0000257"],"is_obsolete":false,"name":"normal DNA replication","termid":"FYPO:0001133"}


id: PBO:0005256
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2.7.4.7","termid":"PBO:0005256"}


id: MONDO:0000067
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete mitochondrial DNA depletion syndrome (obsolete MONDO:0000067)","termid":"MONDO:0000067","xrefs":{"Monarch":{"xref_id":"0000067"}}}


id: GO:0060102
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A collagen and cuticulin-based noncellular, multilayered structure that is synthesized by an underlying ectodermal (hypodermal) cell layer. The cuticle serves essential functions in body morphology, locomotion, and environmental protection. An example of this component is found in Caenorhabditis elegans.","definition_xrefs":["PMID:12619137","GOC:dph","GOC:kmv","ISSN:15518507"],"direct_ancestors":[{"relation_name":"is_a","term_name":"specialized extracellular matrix","termid":"GO:0140047"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"cuticular extracellular matrix","synonyms":[{"name":"collagen and cuticulin-based cuticle extracellular matrix","type":"exact"},{"name":"collagen and cuticulin-based exoskeleton extracellular matrix","type":"related"},{"name":"cuticular ECM","type":"exact"}],"termid":"GO:0060102"}


id: PBO:0109601
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CR1 antisense RNA 1","termid":"PBO:0109601"}


id: PBO:0081267
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 33B","termid":"PBO:0081267"}


id: PBO:0031015
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-resistance_to_vanadate","termid":"PBO:0031015"}


id: PBO:0054368
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1762","termid":"PBO:0054368"}


id: PBO:0086635
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YGL036W is not an essential gene","termid":"PBO:0086635"}


id: FYPO:0006490
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell cycle phenotype in which the duration of M phase of the mitotic cell cycle is shorter than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal mitotic M phase progression","termid":"FYPO:0000607"},{"relation_name":"is_a","term_name":"decreased duration of mitotic cell cycle phase","termid":"FYPO:0001070"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0001320","FYPO:0000631","FYPO:0005447","FYPO:0000002"],"is_obsolete":false,"name":"decreased duration of mitotic M phase","synonyms":[{"name":"decreased duration of M phase during mitotic cell cycle","type":"exact"},{"name":"decreased duration of mitosis","type":"related"},{"name":"decreased duration of mitosis during mitotic cell cycle","type":"related"},{"name":"decreased duration of mitosis during vegetative growth","type":"related"},{"name":"decreased duration of mitotic nuclear division","type":"related"},{"name":"decreased mitotic M phase duration","type":"exact"},{"name":"decreased mitotic M phase duration during vegetative growth","type":"exact"},{"name":"reduced duration of mitotic M phase","type":"exact"}],"termid":"FYPO:0006490"}


id: FYPO:0006224
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of ferrous iron ions into a cell occurs to a lower extent than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal ferrous iron import","termid":"FYPO:0006223"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000138","FYPO:0001320","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"decreased ferrous iron import","synonyms":[{"name":"decreased cellular ferrous iron import","type":"exact"},{"name":"decreased ferrous ion import","type":"exact"},{"name":"decreased ferrous ion import across plasma membrane","type":"exact"},{"name":"decreased ferrous iron import during mitotic cell cycle","type":"related"},{"name":"decreased ferrous iron import during vegetative growth","type":"exact"},{"name":"decreased ferrous iron import into cell","type":"narrow"},{"name":"decreased ferrous iron ion import","type":"exact"},{"name":"reduced ferrous iron import","type":"exact"}],"termid":"FYPO:0006224"}


id: GO:0009606
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The movement of an organism, or part of an organism, in response to an external source of stimulus, usually toward or away from it.","definition_xrefs":["GOC:curators","ISBN:0877795088"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to external stimulus","termid":"GO:0009605"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"tropism","secondary_identifiers":["Wikipedia:Tropism"],"termid":"GO:0009606"}


id: PBO:0116545
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial dihydrolipoamide S-acetyltransferase (e2 component), Lat1","termid":"PBO:0116545"}


id: GO:0050113
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: myo-inositol + O2 = D-glucuronate + H2O + H+.","definition_xrefs":["RHEA:23696"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monooxygenase activity","termid":"GO:0004497"},{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on single donors with incorporation of molecular oxygen","termid":"GO:0016701"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"inositol oxygenase activity","secondary_identifiers":["MetaCyc:MYO-INOSITOL-OXYGENASE-RXN","EC:1.13.99.1","Reactome:R-HSA-5678327","KEGG_REACTION:R01184"],"synonyms":[{"name":"MOO activity","type":"related"},{"name":"meso-inositol oxygenase activity","type":"related"},{"name":"myo-inositol oxygenase activity","type":"exact"},{"name":"myo-inositol:oxygen oxidoreductase activity","type":"related"}],"termid":"GO:0050113"}


id: GO:0044874
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a lipoprotein is transported to, or maintained in, a specific location in an outer membrane.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lipoprotein localization to membrane","termid":"GO:0044873"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0008150","GO:0051179"],"is_obsolete":false,"name":"lipoprotein localization to outer membrane","termid":"GO:0044874"}


id: FYPO:0004330
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which mitotic sister chromatid separation is normal (i.e. indistinguishable from wild type) at telomeres. Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis.","definition_xrefs":["PMID:17032733","GO:0051306","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal mitotic sister chromatid separation","termid":"FYPO:0004301"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001312","FYPO:0001320","FYPO:0000002","FYPO:0000257"],"is_obsolete":false,"name":"normal mitotic telomeric DNA separation","synonyms":[{"name":"normal mitotic chromosome separation at telomere","type":"exact"},{"name":"normal mitotic sister chromatid separation at telomere","type":"exact"},{"name":"normal mitotic telomere disjunction","type":"exact"},{"name":"normal mitotic telomeric DNA separation during vegetative growth","type":"exact"},{"name":"normal telomere separation","type":"exact"},{"name":"normal telomeric DNA separation during mitotic cell cycle","type":"related"}],"termid":"FYPO:0004330"}


id: PBO:0003409
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"inner centromere protein, shugoshin, Sgo1","termid":"PBO:0003409"}


id: GO:0099109
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds activation of a potassium ion channel.","definition_xrefs":["PMID:9429760","GOC:dos"],"gene_count":0,"genotype_count":0,"name":"obsolete potassium channel activating, G protein-coupled receptor signaling pathway (obsolete GO:0099109)","synonyms":[{"name":"potassium channel activating, G-protein coupled receptor signaling pathway","type":"exact"}],"termid":"GO:0099109"}


id: MONDO:0043919
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Inflammation of the lung due to harmful effects of ionizing or non-ionizing radiation.","definition_xrefs":["MESH:D017564"],"direct_ancestors":[{"relation_name":"is_a","term_name":"interstitial lung disease","termid":"MONDO:0015925"},{"relation_name":"is_a","term_name":"radiation-induced disorder","termid":"MONDO:0043459"},{"relation_name":"is_a","term_name":"pneumonitis","termid":"MONDO:0043905"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"radiation pneumonitis","secondary_identifiers":["icd11.foundation:1914397767","SCTID:84004001"],"synonyms":[{"name":"Pneumonitides, radiation","type":"related"},{"name":"fibrosis, radiation","type":"related"},{"name":"pneumonia, radiation","type":"related"},{"name":"pneumonitis, radiation","type":"related"},{"name":"Pneumonias, radiation","type":"related"},{"name":"pulmonary radiation alveolitis","type":"related"},{"name":"radiation Pneumonias","type":"related"},{"name":"radiation Pneumonitides","type":"related"},{"name":"radiation fibrosis","type":"related"},{"name":"radiation pneumonia","type":"related"},{"name":"radiation pneumonitis","type":"exact"}],"termid":"MONDO:0043919","xrefs":{"Monarch":{"xref_id":"0043919"}}}


id: PBO:0046509
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ERICH3 antisense RNA 1","termid":"PBO:0046509"}


id: MONDO:0032795
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant non-syndromic intellectual disability","termid":"MONDO:0015802"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426"],"is_obsolete":false,"name":"intellectual developmental disorder 59","secondary_identifiers":["UMLS:C5193190","OMIM:618522","MEDGEN:1678593"],"synonyms":[{"name":"INTELLECTUAL DEVELOPMENTAL DISORDER 59","type":"related"},{"name":"MRD59","type":"related"},{"name":"Mental Retardation, Autosomal Dominant 59","type":"related"},{"name":"intellectual developmental disorder 59","type":"exact"}],"termid":"MONDO:0032795","xrefs":{"Monarch":{"xref_id":"0032795"}}}


id: GO:0048818
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of hair follicle maturation.","definition_xrefs":["GOC:devbiol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of hair follicle maturation","termid":"GO:0048819"},{"relation_name":"is_a","term_name":"positive regulation of hair follicle development","termid":"GO:0051798"},{"relation_name":"positively_regulates","term_name":"hair follicle maturation","termid":"GO:0048820"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of hair follicle maturation","synonyms":[{"name":"activation of hair follicle maturation","type":"narrow"},{"name":"stimulation of hair follicle maturation","type":"narrow"},{"name":"up regulation of hair follicle maturation","type":"exact"},{"name":"up-regulation of hair follicle maturation","type":"exact"},{"name":"upregulation of hair follicle maturation","type":"exact"}],"termid":"GO:0048818"}


id: PBO:0058093
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4309","termid":"PBO:0058093"}


id: PR:Q09116
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- spn2 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q09116"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"septin homolog spn2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC821.06","synonyms":[{"name":"Spom972h-spn2","type":"exact"}],"termid":"PR:Q09116"}


id: PBO:0026710
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_MCM_complex_binding","termid":"PBO:0026710"}


id: GO:0042454
data:
  {"annotated_genes":["SJAG_01673","SJAG_02580","SJAG_02959"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[89399,89400],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006154"},{"annotations":[91010],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006216"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ribonucleoside metabolic process","termid":"GO:0009119"},{"relation_name":"is_a","term_name":"nucleoside catabolic process","termid":"GO:0009164"}],"gene_count":3,"genes_by_uniquename":{"SJAG_01673":null,"SJAG_02580":null,"SJAG_02959":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0055086"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0055086"],"is_obsolete":false,"name":"ribonucleoside catabolic process","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"ribonucleoside breakdown","type":"exact"},{"name":"ribonucleoside catabolism","type":"exact"},{"name":"ribonucleoside degradation","type":"exact"}],"termid":"GO:0042454","terms_by_termid":{"GO:0006154":null,"GO:0006216":null}}


id: MONDO:0054560
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"anauxetic dysplasia","termid":"MONDO:0011773"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"anauxetic dysplasia 1","secondary_identifiers":["MEDGEN:1638106","OMIM:607095","UMLS:C4551965","DOID:0050640"],"synonyms":[{"name":"ANXD1","type":"related"},{"name":"anauxetic dysplasia","type":"related"},{"name":"anauxetic dysplasia 1","type":"exact"},{"name":"spondyloepimetaphyseal dysplasia, anauxetic type","type":"related"},{"name":"spondylometaepiphyseal dysplasia, Menger type","type":"related"},{"name":"spondylometaepiphyseal dysplasia, anauxetic type","type":"related"}],"termid":"MONDO:0054560","xrefs":{"Monarch":{"xref_id":"0054560"}}}


id: MONDO:0035472
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare genetic primary lymphedema characterized by lymphedema of all four limbs with age of onset ranging from birth to adulthood. Manifestations are of variable severity, and upper limb involvement may develop only later in the disease course. Recurrent episodes of cellulitis and skin infections are observed in severe cases. Varicose veins and venous incompetence have been reported in association.","definition_xrefs":["Orphanet:568051"],"direct_ancestors":[{"relation_name":"is_a","term_name":"primary lymphedema","termid":"MONDO:0019175"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"GJC2-related late-onset primary lymphedema","secondary_identifiers":["UMLS:C5681305","GARD:22299","MEDGEN:1809328"],"termid":"MONDO:0035472","xrefs":{"Monarch":{"xref_id":"0035472"}}}


id: GO:0042882
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which L-arabinose, the L-enantiomer of arabinose, is transported across a lipid bilayer, from one side of a membrane to the other.","definition_xrefs":["GOC:mah","GOC:jsg","GOC:jl","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"arabinose transmembrane transport","termid":"GO:0015751"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0051179","GO:0008150","GO:0006810","GO:0055085"],"is_obsolete":false,"name":"L-arabinose transmembrane transport","synonyms":[{"name":"L-arabinose transport","type":"related"}],"termid":"GO:0042882"}


id: GO:0002024
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process that results in increased metabolic rate in tissues of an organism. It is triggered by the detection of dietary excess. This process is achieved via signaling in the sympathetic nervous system.","definition_xrefs":["PMID:12161655"],"direct_ancestors":[{"relation_name":"is_a","term_name":"adaptive thermogenesis","termid":"GO:1990845"},{"relation_name":"part_of","term_name":"response to dietary excess","termid":"GO:0002021"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"diet induced thermogenesis","termid":"GO:0002024"}


id: PBO:0044853
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"defensin beta 134","termid":"PBO:0044853"}


id: GO:0008041
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete storage protein of fat body (sensu Insecta) (obsolete GO:0008041)","synonyms":[{"name":"storage protein of fat body (sensu Insecta)","type":"exact"}],"termid":"GO:0008041"}


id: GO:0019917
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The dehydration of peptidyl-serine, followed by hydrogenation to produce peptidyl-D-alanine.","definition_xrefs":["RESID:AA0191"],"gene_count":0,"genotype_count":0,"name":"obsolete peptidyl-D-alanine racemization via peptidyl-L-serine (obsolete GO:0019917)","termid":"GO:0019917"}


id: GO:1900014
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The directed movement of a motile cell in response to the presence of 3',5'-cAMP that results in a change in state or activity (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.","definition_xrefs":["PMID:8937985","GOC:pf","GOC:TermGenie","PMID:19363786","PMID:21239624"],"gene_count":0,"genotype_count":0,"name":"obsolete cellular response to calcium ion involved in chemotaxis to cAMP (obsolete GO:1900014)","synonyms":[{"name":"cellular response to Ca2+ ion of chemotaxis to 3',5' cAMP","type":"exact"},{"name":"cellular response to Ca2+ ion of chemotaxis to 3',5'-cAMP","type":"exact"},{"name":"cellular response to Ca2+ ion of chemotaxis to adenosine 3',5'-cyclophosphate","type":"exact"},{"name":"cellular response to Ca2+ ion of chemotaxis to cAMP","type":"related"},{"name":"cellular response to Ca2+ ion of chemotaxis to cyclic AMP","type":"exact"},{"name":"cellular response to calcium ion involved in chemotaxis to cAMP","type":"exact"},{"name":"cellular response to calcium ion of chemotaxis to 3',5' cAMP","type":"related"},{"name":"cellular response to calcium ion of chemotaxis to 3',5'-cAMP","type":"related"},{"name":"cellular response to calcium ion of chemotaxis to adenosine 3',5'-cyclophosphate","type":"related"},{"name":"cellular response to calcium ion of chemotaxis to cAMP","type":"related"},{"name":"cellular response to calcium ion of chemotaxis to cyclic AMP","type":"related"}],"termid":"GO:1900014"}


id: MONDO:0012743
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any Brugada syndrome in which the cause of the disease is a mutation in the CACNB2 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Brugada syndrome","termid":"MONDO:0015263"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"Brugada syndrome 4","secondary_identifiers":["MESH:C567508","UMLS:C2678477","OMIM:611876","DOID:0110221","GARD:10362","MEDGEN:395632"],"synonyms":[{"name":"BRGDA4","type":"exact"},{"name":"Brugada syndrome 4","type":"exact"},{"name":"Brugada syndrome caused by mutation in CACNB2","type":"exact"},{"name":"Brugada syndrome type 4","type":"exact"},{"name":"CACNB2 Brugada syndrome","type":"exact"}],"termid":"MONDO:0012743","xrefs":{"Monarch":{"xref_id":"0012743"}}}


id: PBO:0113037
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cell wall protein with similarity to glucanases; targeted to vacuole via AP-3 pathway; scw4 scw10 double mutants exhibit defects in mating; SCW4 has a paralog, SCW10, that arose from the whole genome duplication","termid":"PBO:0113037"}


id: PBO:0053853
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1122","termid":"PBO:0053853"}


id: MONDO:0008242
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"photomyoclonus, diabetes mellitus, deafness, nephropathy, and cerebral dysfunction","secondary_identifiers":["MESH:C538113","ICD9:583.9","OMIM:172500","SCTID:237612000","MEDGEN:315660","UMLS:C1809475"],"synonyms":[{"name":"Herrmann syndrome","type":"related"},{"name":"hereditary photomyoclonus associated with diabetes mellitus, deafness, nephropathy, and cerebral dysfunction","type":"related"},{"name":"photomyoclonus, diabetes mellitus, deafness, nephropathy, and cerebral dysfunction","type":"exact"}],"termid":"MONDO:0008242","xrefs":{"Monarch":{"xref_id":"0008242"}}}


id: GO:1904047
data:
  {"annotated_genes":["SJAG_03755","SJAG_01269"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[57398,99664],"is_not":false,"summary":null,"term":"GO:1904047"}]},"cv_name":"molecular_function","definition":"Binding to S-adenosyl-L-methionine.","definition_xrefs":["GOC:BHF","PMID:22985361","GOC:TermGenie","GO_REF:0000067","GOC:hal"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cation binding","termid":"GO:0043169"},{"relation_name":"is_a","term_name":"sulfur compound binding","termid":"GO:1901681"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01269":null,"SJAG_03755":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005488"],"is_obsolete":false,"name":"S-adenosyl-L-methionine binding","references_by_uniquename":{"GO_REF:0000104":null,"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-947535","GO:0070283"],"synonyms":[{"name":"radical SAM enzyme activity","type":"narrow"}],"termid":"GO:1904047","terms_by_termid":{"GO:1904047":null}}


id: GO:0043602
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of nitrates, inorganic or organic salts and esters of nitric acid.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"catabolic process","termid":"GO:0009056"},{"relation_name":"is_a","term_name":"nitrate metabolic process","termid":"GO:0042126"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0044281"],"is_obsolete":false,"name":"nitrate catabolic process","synonyms":[{"name":"nitrate disassimilation","type":"exact"},{"name":"nitrate dissimilation","type":"exact"}],"termid":"GO:0043602"}


id: PBO:0068511
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U1 small nuclear 101, pseudogene","termid":"PBO:0068511"}


id: PBO:0087282
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Signal recognition particle (SRP) receptor alpha subunit; contain GTPase domains; involved in SRP-dependent protein targeting; interacts with the beta subunit, Srp102p","termid":"PBO:0087282"}


id: MONDO:0010010
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Schinzel-Giedion syndrome (SGS) is an ectodermal dysplasia syndrome chiefly characterized by a distinctive facial dysmorphism, hydronephrosis, severe developmental delay, typical skeletal malformations, and genital and cardiac anomalies.","definition_xrefs":["Orphanet:798"],"direct_ancestors":[{"relation_name":"is_a","term_name":"congenital nervous system disorder","termid":"MONDO:0002320"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-variable intellectual disability syndrome","termid":"MONDO:0015160"},{"relation_name":"is_a","term_name":"ectodermal dysplasia syndrome","termid":"MONDO:0019287"},{"relation_name":"is_a","term_name":"autosomal dominant syndromic intellectual disability","termid":"MONDO:0100601"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0002320"},{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0000426","MONDO:0002320","MONDO:0005093"],"is_obsolete":false,"name":"Schinzel-Giedion syndrome","secondary_identifiers":["UMLS:C0265227","icd11.foundation:1542318431","OMIM:269150","NORD:1694","DOID:0070509","GARD:117","ICD9:759.89","MedDRA:10063540","MEDGEN:120517","NCIT:C129308","SCTID:18899000","MESH:C536632"],"synonyms":[{"name":"SGS","type":"exact"},{"name":"Schinzel Giedion Syndrome","type":"exact"},{"name":"Schinzel Giedion midface-retraction syndrome","type":"related"},{"name":"Schinzel Giedion syndrome","type":"related"},{"name":"Schinzel-Giedion midface retraction syndrome","type":"related"},{"name":"Schinzel-Giedion midface-retraction syndrome","type":"exact"},{"name":"Schinzel-Giedion syndrome","type":"exact"},{"name":"Sgs","type":"related"}],"termid":"MONDO:0010010","xrefs":{"Monarch":{"xref_id":"0010010"}}}


id: PBO:0003979
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"4.2.1.19","termid":"PBO:0003979"}


id: MONDO:0015827
data:
  {"annotated_genes":["SJAG_00516","SJAG_00136","SJAG_01183"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86837],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008368"},{"annotations":[87114],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009968"},{"annotations":[87926],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011268"},{"annotations":[86984],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012700"}]},"cv_name":"mondo","definition":"Distal renal tubular acidosis (dRTA) is a disorder of impaired net acid secretion by the distal tubule characterized by hyperchloremic metabolic acidosis. The classic form is often associated with hypokalemia whereas other forms of acquired dRTA may be associated with hypokalemia, hyperkalemia or normokalemia.","definition_xrefs":["Orphanet:18"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inherited kidney disorder","termid":"MONDO:0100191"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00136":null,"SJAG_00516":null,"SJAG_01183":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240"],"is_obsolete":false,"name":"distal renal tubular acidosis","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["ICD9:588.89","NORD:1969","SCTID:236461000","HP:0008341","OMIMPS:179800","MEDGEN:853429","MedDRA:10045224","UMLS:C1704380","GARD:4667"],"synonyms":[{"name":"Primary Distal Renal Tubular Acidosis","type":"exact"},{"name":"classic RTA","type":"exact"},{"name":"dRTA","type":"exact"},{"name":"distal renal tubular acidosis","type":"exact"},{"name":"distal renal tubular acidosis (disease)","type":"exact"},{"name":"familial distal primary acidosis","type":"exact"},{"name":"renal tubular acidosis type 1","type":"exact"},{"name":"renal tubular acidosis, distal","type":"related"}],"termid":"MONDO:0015827","terms_by_termid":{"MONDO:0008368":null,"MONDO:0009968":null,"MONDO:0011268":null,"MONDO:0012700":null},"xrefs":{"Monarch":{"xref_id":"0015827"}}}


id: PBO:0076644
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T-box transcription factor 1","termid":"PBO:0076644"}


id: PBO:0056441
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MARK2 pseudogene 14","termid":"PBO:0056441"}


id: GO:0016521
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"The action characteristic of pituitary adenylate cyclase activating polypeptide, a peptide produced in the hypothalamus that binds to receptors to exert pleiotropic effects including control of neurotransmitter release, vasodilation, bronchodilation, activation of intestinal motility, increase in insulin and histamine secretion, immune modulation, and stimulation of cell proliferation and differentiation.","definition_xrefs":["PMID:19805477","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hormone activity","termid":"GO:0005179"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140677"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0098772"},{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0140677","GO:0005488","GO:0005515","GO:0098772"],"is_obsolete":false,"name":"pituitary adenylate cyclase activating polypeptide activity","synonyms":[{"name":"pituitary adenylyl cyclase activating polypeptide activity","type":"exact"}],"termid":"GO:0016521"}


id: GO:0061739
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The protein lipidation process by which phosphatidylethanolamine is conjugated to a protein of the ATG8 family, leading to membrane insertion of the protein as a step in autophagosome assembly.","definition_xrefs":["PMID:11096062","GOC:dph","GOC:autophagy","PMID:11100732","PMID:15277523"],"direct_ancestors":[{"relation_name":"is_a","term_name":"C-terminal protein lipidation","termid":"GO:0006501"},{"relation_name":"part_of","term_name":"autophagosome assembly","termid":"GO:0000045"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"part_of","termid":"GO:0042158"},{"rel_name":"part_of","termid":"GO:0006914"}],"interesting_parent_ids":["GO:0008150","GO:0044085","GO:0042158","GO:0006914"],"is_obsolete":false,"name":"protein lipidation involved in autophagosome assembly","termid":"GO:0061739"}


id: PBO:0064019
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"piwi-interacting RNA cluster 53","termid":"PBO:0064019"}


id: PBO:0042064
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coiled-coil domain containing 127","termid":"PBO:0042064"}


id: PBO:0038944
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"alcohol dehydrogenase iron containing 1","termid":"PBO:0038944"}


id: GO:0052934
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2 [Fe(III)cytochrome c] + a primary alcohol = 2 [Fe(II)cytochrome c] + an aldehyde + 2 H+.","definition_xrefs":["RHEA:51020"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor","termid":"GO:0016898"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"alcohol dehydrogenase (cytochrome c) activity","secondary_identifiers":["KEGG_REACTION:R05198","MetaCyc:RXN-11333","GO:0052935","KEGG_REACTION:R05285","GO:0018468","GO:0052936","EC:1.1.2.8"],"synonyms":[{"name":"2-chloroethanol:cytochrome c oxidoreductase activity","type":"narrow"},{"name":"PQQ-dependent alcohol dehydrogenase activity","type":"exact"},{"name":"alcohol dehydrogenase (acceptor) activity","type":"broad"},{"name":"alcohol:(acceptor) oxidoreductase activity","type":"related"},{"name":"alcohol:acceptor oxidoreductase activity","type":"related"},{"name":"alcohol:cytochrome c oxidoreductase activity","type":"exact"},{"name":"ethanol:cytochrome c oxidoreductase activity","type":"narrow"},{"name":"quinoprotein alcohol dehydrogenase activity","type":"related"}],"termid":"GO:0052934"}


id: PBO:0017494
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hexose transmembrane transporter Ght3","termid":"PBO:0017494"}


id: GO:1905572
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of ganglioside GM1 to membrane.","definition_xrefs":["GOC:TermGenie","PMID:1454804","GO_REF:0000078"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ceramide transport","termid":"GO:0035627"},{"relation_name":"is_a","term_name":"glycolipid transport","termid":"GO:0046836"},{"relation_name":"is_a","term_name":"carboxylic acid transport","termid":"GO:0046942"},{"relation_name":"is_a","term_name":"localization within membrane","termid":"GO:0051668"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0006810","GO:0051179","GO:0008150"],"is_obsolete":false,"name":"ganglioside GM1 transport to membrane","termid":"GO:1905572"}


id: PBO:0018281
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mediator complex subunit Med17","termid":"PBO:0018281"}


id: PBO:0071701
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L39","termid":"PBO:0071701"}


id: MONDO:0850421
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An acute pancreatits that is characterized by acute inflammation of the pancreas in which the initial edematous pancreatitis evolved into necrosis accompanied by hemorrhage.","definition_xrefs":["DOID:0080999"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acute pancreatitis","termid":"MONDO:0006515"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"acute hemorrhagic pancreatitis","secondary_identifiers":["MEDGEN:541079","UMLS:C0267940"],"termid":"MONDO:0850421","xrefs":{"Monarch":{"xref_id":"0850421"}}}


id: PBO:0004712
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Tel2 interacting protein Tti2, predicted ASTRA complex subunit","termid":"PBO:0004712"}


id: GO:0018643
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: carbon disulfide + NADH + H+ + O2 = [S] + H2O + NAD+ + carbonyl sulfide.","definition_xrefs":["UM-BBD_reactionID:r0599"],"gene_count":0,"genotype_count":0,"name":"obsolete carbon disulfide oxygenase activity (obsolete GO:0018643)","synonyms":[{"name":"carbon disulphide oxygenase activity","type":"exact"}],"termid":"GO:0018643"}


id: GO:0004299
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the cleavage at peptide bonds with very broad specificity.","definition_xrefs":["EC:3.4.25.1"],"gene_count":0,"genotype_count":0,"name":"obsolete proteasome endopeptidase activity (obsolete GO:0004299)","synonyms":[{"name":"multicatalytic endopeptidase","type":"related"},{"name":"proteasome","type":"related"},{"name":"proteasome endopeptidase activity","type":"exact"},{"name":"proteasome endopeptidase complex","type":"related"}],"termid":"GO:0004299"}


id: GO:0044141
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the symbiont's progression from an initial condition to a later condition, on or near the cells or tissues of the host organism.","definition_xrefs":["GOC:pamgo_curators","GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of development of symbiont on or near host surface (obsolete GO:0044141)","termid":"GO:0044141"}


id: MONDO:0001174
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A disorder of the vasculature of the cornea.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ocular vascular disorder","termid":"MONDO:0005552"},{"relation_name":"is_a","term_name":"conjunctival disorder","termid":"MONDO:0006170"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"conjunctival vascular disorder","secondary_identifiers":["NCIT:C35116","SCTID:74100001","ICD9:372.74","ICD10CM:H11.41","UMLS:C0042370","MEDGEN:12052","DOID:10989"],"synonyms":[{"name":"conjunctival vascular abnormality","type":"exact"},{"name":"conjunctival vascular disorder","type":"exact"},{"name":"conjunctival vasculature disease","type":"exact"},{"name":"conjunctival vasculature disease or disorder","type":"exact"},{"name":"disease of conjunctival vasculature","type":"exact"},{"name":"disease or disorder of conjunctival vasculature","type":"exact"},{"name":"disorder of conjunctival vasculature","type":"exact"},{"name":"vascular abnormalities of conjunctiva","type":"exact"}],"termid":"MONDO:0001174","xrefs":{"Monarch":{"xref_id":"0001174"}}}


id: PBO:0001057
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"curved DNA-binding protein Cdb4, peptidase family","termid":"PBO:0001057"}


id: PBO:0044765
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DEAD-box helicase 49","termid":"PBO:0044765"}


id: GO:0000960
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.","definition_xrefs":["GOC:krc","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of catabolic process","termid":"GO:0009894"},{"relation_name":"is_a","term_name":"regulation of RNA metabolic process","termid":"GO:0051252"},{"relation_name":"regulates","term_name":"mitochondrial RNA catabolic process","termid":"GO:0000957"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of mitochondrial RNA catabolic process","termid":"GO:0000960"}


id: PBO:0084772
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial ornithine acetyltransferase; catalyzes the fifth step in arginine biosynthesis; also possesses acetylglutamate synthase activity, regenerates acetylglutamate while forming ornithine","termid":"PBO:0084772"}


id: GO:2001297
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of N(omega)-methyl-L-arginine.","definition_xrefs":["PMID:10510241","GOC:rs"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified amino acid catabolic process","termid":"GO:0042219"},{"relation_name":"is_a","term_name":"L-amino acid catabolic process","termid":"GO:0170035"},{"relation_name":"is_a","term_name":"non-proteinogenic amino acid catabolic process","termid":"GO:0170044"},{"relation_name":"is_a","term_name":"N(omega)-methyl-L-arginine metabolic process","termid":"GO:2001296"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0006520"}],"interesting_parent_ids":["GO:0008150","GO:0044281","GO:0006520"],"is_obsolete":false,"name":"N(omega)-methyl-L-arginine catabolic process","synonyms":[{"name":"N(omega)-methyl-L-arginine breakdown","type":"exact"},{"name":"N(omega)-methyl-L-arginine catabolism","type":"exact"},{"name":"N(omega)-methyl-L-arginine degradation","type":"exact"}],"termid":"GO:2001297"}


id: PBO:0051103
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin heavy variable 1-14 (pseudogene)","termid":"PBO:0051103"}


id: PBO:0073146
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SEC23 interacting protein","termid":"PBO:0073146"}


id: PBO:0025477
data:
  {"annotation_feature_type":"gene","cv_name":"disease_associated","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Fabry disease","termid":"PBO:0025477"}


id: PBO:0005344
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP-dependent RNA helicase Sum3","termid":"PBO:0005344"}


id: GO:0018662
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: phenol + NADPH + H+ + O2 = catechol + NADP+ + H2O.","definition_xrefs":["EC:1.14.13.7"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen","termid":"GO:0016709"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0016491","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"phenol 2-monooxygenase activity","secondary_identifiers":["UM-BBD_enzymeID:r0696","RHEA:17061","MetaCyc:PHENOL-2-MONOOXYGENASE-RXN"],"synonyms":[{"name":"phenol hydroxylase activity","type":"related"},{"name":"phenol o-hydroxylase activity","type":"related"},{"name":"phenol,NADPH:oxygen oxidoreductase (2-hydroxylating)","type":"related"}],"termid":"GO:0018662"}


id: MONDO:1012315
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"congenital erythropoietic porphyria, non-human animal","termid":"MONDO:1011742"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"congenital erythropoietic porphyria, zebu cattle","secondary_identifiers":["OMIA:001175-9915"],"termid":"MONDO:1012315","xrefs":{"Monarch":{"xref_id":"1012315"}}}


id: PBO:0110039
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lncRNA papillary thyroid carcinoma tumor suppressor","termid":"PBO:0110039"}


id: MONDO:0012830
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"10q22.3q23.3 microdeletion syndrome is a rare partial autosomal monosomy characterized by a mild facial dysmorphism variably including macrocephaly, broad forehead, hypertelorism or hypotelorism, deep-set eyes, upslanting or downslanting palpebral fissures, low-set ears, flat nasal bridge, smooth philtrum, thin upper lip), cleft palate, cerebellar and cardiac malformations, psychomotor development delay, and behavioral abnormalities (attention deficit hyperactivity disorder, autism). Other rare features may include congenital breast aplasia, arachnodactyly, joint hyperlaxity, club feet, feeding difficulties, failure to thrive.","definition_xrefs":["Orphanet:276413"],"direct_ancestors":[{"relation_name":"is_a","term_name":"partial monosomy of the long arm of chromosome 10","termid":"MONDO:0016909"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 10q23 deletion syndrome","secondary_identifiers":["GARD:17280","DOID:0060389","UMLS:C4225669","MEDGEN:906099","MESH:C567385","OMIM:612242"],"synonyms":[{"name":"10q22.3q23 microdeletion syndrome","type":"related"},{"name":"10q22.3q23.3 microdeletion syndrome","type":"related"},{"name":"Del(10)(q22.3q23.3)","type":"exact"},{"name":"chromosome 10Q22.3-q23.2 deletion syndrome","type":"related"},{"name":"chromosome 10q22.3-q23.2 deletion syndrome","type":"related"},{"name":"chromosome 10q23 deletion syndrome","type":"exact"},{"name":"deletion 10q22.3q23.3","type":"exact"},{"name":"juvenile polyposis of infancy","type":"related"},{"name":"juvenile polyposis, infantile","type":"related"},{"name":"monosomy 10q22.3q23.3","type":"exact"}],"termid":"MONDO:0012830","xrefs":{"Monarch":{"xref_id":"0012830"}}}


id: GO:1902283
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of primary amine oxidase activity.","definition_xrefs":["GOC:TermGenie","PMID:23349812"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of primary amine oxidase activity (obsolete GO:1902283)","synonyms":[{"name":"down regulation of amine oxidase (copper-containing) activity","type":"narrow"},{"name":"down regulation of primary amine oxidase activity","type":"exact"},{"name":"down regulation of primary-amine:oxygen oxidoreductase (deaminating) activity","type":"exact"},{"name":"down-regulation of amine oxidase (copper-containing) activity","type":"narrow"},{"name":"down-regulation of primary amine oxidase activity","type":"exact"},{"name":"down-regulation of primary-amine:oxygen oxidoreductase (deaminating) activity","type":"exact"},{"name":"downregulation of amine oxidase (copper-containing) activity","type":"narrow"},{"name":"downregulation of primary amine oxidase activity","type":"exact"},{"name":"downregulation of primary-amine:oxygen oxidoreductase (deaminating) activity","type":"exact"},{"name":"inhibition of amine oxidase (copper-containing) activity","type":"narrow"},{"name":"inhibition of primary amine oxidase activity","type":"narrow"},{"name":"inhibition of primary-amine:oxygen oxidoreductase (deaminating) activity","type":"narrow"},{"name":"negative regulation of amine oxidase (copper-containing) activity","type":"narrow"},{"name":"negative regulation of primary-amine:oxygen oxidoreductase (deaminating) activity","type":"exact"}],"termid":"GO:1902283"}


id: PBO:0047754
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"focadhesin","termid":"PBO:0047754"}


id: GO:0070959
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil.","definition_xrefs":["GOC:add","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of neutrophil mediated killing of fungus","termid":"GO:0070953"},{"relation_name":"is_a","term_name":"negative regulation of neutrophil mediated killing of symbiont cell","termid":"GO:0070955"},{"relation_name":"negatively_regulates","term_name":"neutrophil-mediated killing of fungus","termid":"GO:0070947"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of neutrophil mediated killing of fungus","synonyms":[{"name":"down regulation of neutrophil mediated killing of fungus","type":"exact"},{"name":"down-regulation of neutrophil mediated killing of fungus","type":"exact"},{"name":"downregulation of neutrophil mediated killing of fungus","type":"exact"},{"name":"inhibition of neutrophil mediated killing of fungus","type":"narrow"}],"termid":"GO:0070959"}


id: GO:0042315
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the hydrolysis of dipeptides, preferentially hydrophobic dipeptides including prolyl amino acids.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete cytosol nonspecific dipeptidase activity (obsolete GO:0042315)","synonyms":[{"name":"cytosol nonspecific dipeptidase activity","type":"exact"}],"termid":"GO:0042315"}


id: PBO:0110511
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ANKyrin repeats","termid":"PBO:0110511"}


id: GO:0034584
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a piRNA, a Piwi-associated RNA, a 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.","definition_xrefs":["GOC:kmv"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulatory RNA binding","termid":"GO:0061980"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003723"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0003723","GO:0003674","GO:0005488"],"is_obsolete":false,"name":"piRNA binding","synonyms":[{"name":"Piwi-associated RNA binding","type":"exact"}],"termid":"GO:0034584"}


id: PBO:0043799
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CPLANE1 antisense RNA 1","termid":"PBO:0043799"}


id: GO:2001216
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of hydroxymethylglutaryl-CoA reductase (NADPH) activity.","definition_xrefs":["GOC:al"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity (obsolete GO:2001216)","synonyms":[{"name":"negative regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity","type":"related"},{"name":"negative regulation of HMG-CoA reductase activity","type":"related"}],"termid":"GO:2001216"}


id: GO:1903452
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of G1 to G0 transition.","definition_xrefs":["GOC:di","GOC:TermGenie","PMID:24088570","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cell cycle process","termid":"GO:0090068"},{"relation_name":"is_a","term_name":"regulation of G1 to G0 transition","termid":"GO:1903450"},{"relation_name":"positively_regulates","term_name":"G1 to G0 transition","termid":"GO:0070314"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0008150","GO:0007049"],"is_obsolete":false,"name":"positive regulation of G1 to G0 transition","synonyms":[{"name":"activation of G1 to G0 transition","type":"narrow"},{"name":"activation of G1/G0 transition","type":"narrow"},{"name":"activation of cell cycle quiescence","type":"related"},{"name":"activation of establishment of cell quiescence","type":"narrow"},{"name":"activation of stationary phase","type":"related"},{"name":"positive regulation of G1/G0 transition","type":"exact"},{"name":"positive regulation of cell cycle quiescence","type":"related"},{"name":"positive regulation of establishment of cell quiescence","type":"exact"},{"name":"positive regulation of stationary phase","type":"related"},{"name":"up regulation of G1 to G0 transition","type":"exact"},{"name":"up regulation of G1/G0 transition","type":"exact"},{"name":"up regulation of cell cycle quiescence","type":"related"},{"name":"up regulation of establishment of cell quiescence","type":"exact"},{"name":"up regulation of stationary phase","type":"related"},{"name":"up-regulation of G1 to G0 transition","type":"exact"},{"name":"up-regulation of G1/G0 transition","type":"exact"},{"name":"up-regulation of cell cycle quiescence","type":"related"},{"name":"up-regulation of establishment of cell quiescence","type":"exact"},{"name":"up-regulation of stationary phase","type":"related"},{"name":"upregulation of G1 to G0 transition","type":"exact"},{"name":"upregulation of G1/G0 transition","type":"exact"},{"name":"upregulation of cell cycle quiescence","type":"related"},{"name":"upregulation of establishment of cell quiescence","type":"exact"},{"name":"upregulation of stationary phase","type":"related"}],"termid":"GO:1903452"}


id: PBO:0029853
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_histone_H4-K5,_H4-K8,_H4-K12_and_H4-K16_acetylation_at_centromere_outer_repeat","termid":"PBO:0029853"}


id: PBO:0076414
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TATA-box binding protein associated factor 7 like","termid":"PBO:0076414"}


id: GO:0060947
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized cell acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers.","definition_xrefs":["GOC:mtg_heart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cardiocyte differentiation","termid":"GO:0035051"},{"relation_name":"is_a","term_name":"vascular associated smooth muscle cell differentiation","termid":"GO:0035886"},{"relation_name":"part_of","term_name":"coronary vasculature development","termid":"GO:0060976"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cardiac vascular smooth muscle cell differentiation","synonyms":[{"name":"heart vascular smooth muscle cell differentiation","type":"exact"}],"termid":"GO:0060947"}


id: PBO:0087870
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Transcriptional co-activator that regulates mating-type-specific genes; targets the transcription factor Mcm1p to the promoters of alpha-specific genes; one of two genes encoded by the MATalpha mating type cassette","termid":"PBO:0087870"}


id: PBO:0067530
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 674, pseudogene","termid":"PBO:0067530"}


id: FYPO:0004807
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell morphology phenotype in which the cell is narrower than normal at the point where cell fusion occurred during mating. Normally, the cell expands at the fusion site after fusion takes place.","definition_xrefs":["PomBase:mah","PMID:25825517"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal cell shape","termid":"FYPO:0001126"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000005"}],"interesting_parent_ids":["FYPO:0000005","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"narrow cell fusion site following mating","synonyms":[{"name":"narrow cell fusion site following conjugation","type":"exact"},{"name":"narrow cell fusion site following conjugation with cellular fusion","type":"exact"},{"name":"narrow cell-cell fusion site following conjugation with cellular fusion","type":"exact"}],"termid":"FYPO:0004807"}


id: PBO:0048342
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glyceraldehyde 3 phosphate dehydrogenase pseudogene 53","termid":"PBO:0048342"}


id: MONDO:0008253
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"platelet aggregation, spontaneous","secondary_identifiers":["UMLS:C1868263","MEDGEN:401406","OMIM:173400","MESH:C566800"],"synonyms":[{"name":"platelet aggregation, spontaneous","type":"exact"}],"termid":"MONDO:0008253","xrefs":{"Monarch":{"xref_id":"0008253"}}}


id: PBO:0084046
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"G protein gamma subunit; forms dimer with Ste4p to activate mating signaling pathway, heterotrimer with Gpa1p, Ste4p to dampen signaling; C-terminus is palmitoylated and farnesylated, which are required for normal signaling; N-terminal phosphorylation of Ste18p functions synergistically with Fus3p docking site on Ste5p to restrict Ste5p plasma membrane recruitment and signaling; combinatorial phosphorylation at S3 and S7, by pheromone and pH stress, modulates Ste18p structure, Fus3p activation","termid":"PBO:0084046"}


id: MONDO:0002188
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign neoplasm that arises from sweat glands in the vulva and is characterized by the presence of lobules composed of epithelial cells with clear cytoplasm.","definition_xrefs":["NCIT:C40312"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vulvar benign neoplasm","termid":"MONDO:0000643"},{"relation_name":"is_a","term_name":"nodular hidradenoma","termid":"MONDO:0002189"},{"relation_name":"is_a","term_name":"benign neoplasm of sweat gland","termid":"MONDO:0021489"},{"relation_name":"is_a","term_name":"benign epithelial skin neoplasm","termid":"MONDO:0024666"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"vulvar nodular hidradenoma","secondary_identifiers":["DOID:2060","MEDGEN:276994","UMLS:C1520091"],"synonyms":[{"name":"mammalian vulva nodular hidradenoma","type":"exact"},{"name":"nodular hidradenoma of mammalian vulva","type":"exact"},{"name":"vulvar nodular hidradenoma","type":"exact"}],"termid":"MONDO:0002188","xrefs":{"Monarch":{"xref_id":"0002188"}}}


id: MONDO:0008209
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Char syndrome is characterized by the triad of patent ductus arteriosus (PDA), facial dysmorphism and hand anomalies.","definition_xrefs":["Orphanet:46627"],"direct_ancestors":[{"relation_name":"is_a","term_name":"patent ductus arteriosus","termid":"MONDO:0011827"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-variable intellectual disability syndrome","termid":"MONDO:0015160"},{"relation_name":"is_a","term_name":"syndromic congenital heart disease","termid":"MONDO:0100614"},{"relation_name":"is_a","term_name":"TFAP2B-related congenital heart disease spectrum disorder","termid":"MONDO:1010098"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"Char syndrome","secondary_identifiers":["MESH:C566815","MEDGEN:358356","OMIM:169100","UMLS:C1868570","SCTID:703534001","DOID:0060563","GARD:1237","ICD9:759.89"],"synonyms":[{"name":"CHAR","type":"related"},{"name":"CHAR syndrome","type":"related"},{"name":"Char","type":"related"},{"name":"Char syndrome","type":"exact"},{"name":"patent ductus arteriosus with Facial Dysmorphism and abnormal fifth digits","type":"related"},{"name":"patent ductus arteriosus with facial dysmorphism and abnormal fifth digits","type":"exact"}],"termid":"MONDO:0008209","xrefs":{"Monarch":{"xref_id":"0008209"}}}


id: SO:0000964
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"Structural unit composed of a self-replicating, double-stranded, linear RNA molecule.","definition_xrefs":["SO:ma"],"direct_ancestors":[{"relation_name":"has_quality","term_name":"linear","termid":"SO:0000987"},{"relation_name":"is_a","term_name":"double_stranded_RNA_chromosome","termid":"SO:0000965"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"linear_double_stranded_RNA_chromosome","synonyms":[{"name":"linear double stranded RNA chromosome","type":"exact"}],"termid":"SO:0000964"}


id: FYPO:0003089
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at sites within the eukaryotic rDNA repeat spacer is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal chromosome organization","termid":"FYPO:0000641"},{"relation_name":"is_a","term_name":"abnormal cellular component organization during vegetative growth","termid":"FYPO:0001353"},{"relation_name":"is_a","term_name":"abnormal replication fork arrest","termid":"FYPO:0003088"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000641"},{"rel_name":"is_a","termid":"FYPO:0000293"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0001985","FYPO:0000002","FYPO:0005447","FYPO:0000293","FYPO:0000641"],"is_obsolete":false,"name":"abnormal replication fork arrest at rDNA repeats","synonyms":[{"name":"abnormal replication fork arrest at rDNA repeats during mitotic cell cycle","type":"related"},{"name":"abnormal replication fork arrest at rDNA repeats during vegetative growth","type":"exact"},{"name":"abnormal replication fork arrest at ribosomal DNA repeats","type":"exact"}],"termid":"FYPO:0003089"}


id: PBO:0005230
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ino80 complex subunit (predicted)","termid":"PBO:0005230"}


id: FYPO:0002095
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular response to a DNA damage stimulus.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased protein phosphorylation during vegetative growth","termid":"FYPO:0001038"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0002274","FYPO:0000002","FYPO:0001985","FYPO:0005447","FYPO:0002494","FYPO:0001320"],"is_obsolete":false,"name":"increased protein phosphorylation during cellular response to DNA damage","synonyms":[{"name":"increased protein phosphorylation during cellular response to DNA damage during mitotic cell cycle","type":"related"},{"name":"increased protein phosphorylation during cellular response to DNA damage during vegetative growth","type":"exact"},{"name":"increased protein phosphorylation during cellular response to DNA damaging agent","type":"related"},{"name":"increased protein phosphorylation during response to DNA damage stimulus","type":"exact"}],"termid":"FYPO:0002095"}


id: GO:2000586
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of platelet-derived growth factor receptor signaling pathway","termid":"GO:0010640"},{"relation_name":"regulates","term_name":"platelet-derived growth factor receptor-beta signaling pathway","termid":"GO:0035791"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"regulation of platelet-derived growth factor receptor-beta signaling pathway","synonyms":[{"name":"regulation of PDGF receptor-beta signaling pathway","type":"exact"},{"name":"regulation of PDGFR-beta signaling pathway","type":"exact"},{"name":"regulation of betaPDGF receptor signaling pathway","type":"exact"},{"name":"regulation of platelet-derived growth factor receptor-beta signalling pathway","type":"exact"}],"termid":"GO:2000586"}


id: PBO:0038468
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP binding cassette subfamily A member 7","termid":"PBO:0038468"}


id: MONDO:0019550
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare axonal hereditary motor and sensory neuropathy characterized by progressive axonal neuropathy with limb weakness and severe distal sensory loss in all limbs and acrodystrophic changes leading to painless non-healing ulcers, osteomyelitis, contractures and mutilating lesions with loss of terminal phalanges. One family with three affected siblings is described and there have been no further descriptions in the literature since 1999.","definition_xrefs":["Orphanet:90119"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary motor and sensory neuropathy","termid":"MONDO:0015358"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0005244"],"is_obsolete":false,"name":"hereditary motor and sensory neuropathy with acrodystrophy","secondary_identifiers":["MEDGEN:1669448","UMLS:C4749729","GARD:19124"],"synonyms":[{"name":"AR-CMT2 with acrodystrophy","type":"exact"},{"name":"HMSN with acrodystrophy","type":"exact"},{"name":"autosomal recessive Charcot-Marie-Tooth type 2 with acrodystrophy","type":"exact"},{"name":"autosomal recessive axonal Charcot-Marie-Tooth disease with acrodystrophy","type":"exact"}],"termid":"MONDO:0019550","xrefs":{"Monarch":{"xref_id":"0019550"}}}


id: GO:0044684
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 7,8-dihydromethanopterin + NADPH = 5,6,7,8-tetrahydromethanopterin + NADP.","definition_xrefs":["PMID:15028691","GOC:mengo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor","termid":"GO:0016646"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"dihydromethanopterin reductase activity","secondary_identifiers":["EC:1.5.99.15","RHEA:42804"],"termid":"GO:0044684"}


id: PBO:0084762
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial mitophagy-specific protein; required primarily for mitophagy induced at post-log phase; not required for other types of selective autophagy or macroautophagy; conserved within fungi, but not in higher eukaryotes; ATG33 has a paralog, SCM4, that arose from the whole genome duplication","termid":"PBO:0084762"}


id: MONDO:0007911
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lipoprotein, variant of beta","secondary_identifiers":["UMLS:C1835357","OMIM:152400","MEDGEN:322642"],"synonyms":[{"name":"Beta-lipoprotein, Double","type":"related"},{"name":"lipoprotein, variant of beta","type":"exact"}],"termid":"MONDO:0007911","xrefs":{"Monarch":{"xref_id":"0007911"}}}


id: GO:0002124
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Aggressive behavior performed in defence of a fixed area against intruders, typically conspecifics.","definition_xrefs":["GOC:hjd"],"direct_ancestors":[{"relation_name":"is_a","term_name":"aggressive behavior","termid":"GO:0002118"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"territorial aggressive behavior","synonyms":[{"name":"territorial aggression","type":"exact"}],"termid":"GO:0002124"}


id: PBO:0042982
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromodomain helicase DNA binding protein 8","termid":"PBO:0042982"}


id: PBO:0053721
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 933","termid":"PBO:0053721"}


id: PBO:0002385
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glucan beta-glucosidase Bgl2 (predicted)","termid":"PBO:0002385"}


id: MONDO:1010976
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Huntington disease that occurs in Rhesus monkey.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Huntington disease, non-human animal","termid":"MONDO:1010231"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Huntington disease, Rhesus monkey","secondary_identifiers":["OMIA:000485-9544"],"termid":"MONDO:1010976","xrefs":{"Monarch":{"xref_id":"1010976"}}}


id: GO:0071047
data:
  {"annotated_genes":["SJAG_04818","SJAG_03179","SJAG_04084","SJAG_04006","SJAG_01191","SJAG_01818","SJAG_04824","SJAG_01521","SJAG_03745","SJAG_04321","SJAG_00854","SJAG_04153"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[120182,94060,97732,108301,107092,99056,109295,117308,94890,106224,117747,103902],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0071042"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA.","definition_xrefs":["GOC:krc","GOC:dgf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mRNA catabolic process","termid":"GO:0006402"},{"relation_name":"is_a","term_name":"mRNA destabilization","termid":"GO:0061157"}],"gene_count":12,"genes_by_uniquename":{"SJAG_00854":null,"SJAG_01191":null,"SJAG_01521":null,"SJAG_01818":null,"SJAG_03179":null,"SJAG_03745":null,"SJAG_04006":null,"SJAG_04084":null,"SJAG_04153":null,"SJAG_04321":null,"SJAG_04818":null,"SJAG_04824":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"regulates","termid":"GO:0016071"},{"rel_name":"positively_regulates","termid":"GO:0016071"},{"rel_name":"negatively_regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0016071"}],"interesting_parent_ids":["GO:0010467","GO:0016071","GO:0008150"],"is_obsolete":false,"name":"polyadenylation-dependent mRNA catabolic process","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"poly(A)-dependent mRNA catabolic process","type":"related"}],"termid":"GO:0071047","terms_by_termid":{"GO:0071042":null}}


id: PBO:0091263
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"until Jan-28-2019 this was erroneously annotated as mrpl1602","termid":"PBO:0091263"}


id: GO:1904393
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering.","definition_xrefs":["PMID:7722643","GO_REF:0000058","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of receptor clustering","termid":"GO:1903909"},{"relation_name":"regulates","term_name":"skeletal muscle acetylcholine-gated channel clustering","termid":"GO:0071340"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of skeletal muscle acetylcholine-gated channel clustering","synonyms":[{"name":"regulation of skeletal muscle AChR clustering","type":"exact"},{"name":"regulation of skeletal muscle nicotinic acetylcholine receptor clustering","type":"exact"}],"termid":"GO:1904393"}


id: MONDO:0006455
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare primary thymic carcinoma, characterized by an undifferentiated solid tumor growth, without associated sarcomatoid features.","definition_xrefs":["NCIT:C35718"],"direct_ancestors":[{"relation_name":"is_a","term_name":"undifferentiated carcinoma","termid":"MONDO:0005617"},{"relation_name":"is_a","term_name":"thymic carcinoma","termid":"MONDO:0006451"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0005570","MONDO:0005046"],"is_obsolete":false,"name":"thymic undifferentiated carcinoma","secondary_identifiers":["EFO:1000580","UMLS:C1336865","MEDGEN:234452"],"synonyms":[{"name":"thymic undifferentiated carcinoma","type":"exact"}],"termid":"MONDO:0006455","xrefs":{"Monarch":{"xref_id":"0006455"}}}


id: MONDO:0044800
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A Spitz nevus associated with fibrous stroma formation.","definition_xrefs":["NCIT:C82864"],"direct_ancestors":[{"relation_name":"is_a","term_name":"spitz nevus","termid":"MONDO:0044793"},{"relation_name":"is_a","term_name":"desmoplastic nevus","termid":"MONDO:0044797"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"desmoplastic spitz nevus","secondary_identifiers":["MEDGEN:266159","SCTID:400022009","UMLS:C1275419"],"synonyms":[{"name":"Desmoplastic spitz Nevus","type":"exact"}],"termid":"MONDO:0044800","xrefs":{"Monarch":{"xref_id":"0044800"}}}


id: PBO:0003454
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2.7.6.3","termid":"PBO:0003454"}


id: PBO:0110969
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 3126","termid":"PBO:0110969"}


id: PBO:0005725
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein phosphatase 2C Ptc1","termid":"PBO:0005725"}


id: GO:1903380
data:
  {"annotated_genes":["SJAG_03048","SJAG_01837"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[104202,118539],"is_not":false,"summary":null,"term":"GO:1903380"}]},"cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation.","definition_xrefs":["GO_REF:0000058","GOC:TermGenie","PMID:9490640"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cell cycle process","termid":"GO:0090068"},{"relation_name":"is_a","term_name":"regulation of mitotic chromosome condensation","termid":"GO:1903379"},{"relation_name":"is_a","term_name":"positive regulation of chromosome condensation","termid":"GO:1905821"},{"relation_name":"positively_regulates","term_name":"mitotic chromosome condensation","termid":"GO:0007076"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01837":null,"SJAG_03048":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0007049"},{"rel_name":"regulates","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0007049","GO:0008150"],"is_obsolete":false,"name":"positive regulation of mitotic chromosome condensation","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"activation of mitotic chromosome condensation","type":"narrow"},{"name":"up regulation of mitotic chromosome condensation","type":"exact"},{"name":"up-regulation of mitotic chromosome condensation","type":"exact"},{"name":"upregulation of mitotic chromosome condensation","type":"exact"}],"termid":"GO:1903380","terms_by_termid":{"GO:1903380":null}}


id: PBO:0068876
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 116, pseudogene","termid":"PBO:0068876"}


id: PBO:0091907
data:
  {"annotation_feature_type":"gene","cv_name":"misc","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"a disordered region N-terminal to the YTH domain stabilizes RNA binding, and becomes more ordered upon binding","termid":"PBO:0091907"}


id: GO:0071614
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of an NADPH- and oxygen-dependent reaction that converts linoleic acid to a cis-epoxyoctadecenoic acid.","definition_xrefs":["GOC:BHF","PMID:11042099"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monooxygenase activity","termid":"GO:0004497"},{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen","termid":"GO:0016705"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"linoleic acid epoxygenase activity","synonyms":[{"name":"linoleic acid monooxygenase activity","type":"exact"}],"termid":"GO:0071614"}


id: GO:1903646
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of chaperone-mediated protein folding.","definition_xrefs":["PMID:24375412","GOC:TermGenie","GO_REF:0000058"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of chaperone-mediated protein folding (obsolete GO:1903646)","termid":"GO:1903646"}


id: PBO:0005397
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"possible false positive domain, EF hand","termid":"PBO:0005397"}


id: PBO:0041421
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 8 open reading frame 33","termid":"PBO:0041421"}


id: MONDO:0010870
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A distal myopathy characterized by weakness of the muscles of the anterior compartment of lower limbs, appearing in the fourth to seventh decade of life.","definition_xrefs":["Orphanet:609"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant distal myopathy","termid":"MONDO:0016108"},{"relation_name":"is_a","term_name":"autosomal dominant titinopathy","termid":"MONDO:0100494"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"},{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0005336","MONDO:0000426","MONDO:0002320"],"is_obsolete":false,"name":"tibial muscular dystrophy","secondary_identifiers":["DOID:0111078","MEDGEN:333047","SCTID:698846009","UMLS:C1838244","OMIM:600334","GARD:13154"],"synonyms":[{"name":"Finnish tibial muscular dystrophy","type":"exact"},{"name":"TMD","type":"exact"},{"name":"Tmd","type":"related"},{"name":"Udd myopathy","type":"exact"},{"name":"Udd type distal myopathy","type":"exact"},{"name":"distal myopathy, Udd type","type":"exact"},{"name":"distal titinopathy","type":"exact"},{"name":"tardive tibial muscular dystrophy","type":"exact"},{"name":"tibial muscular dystrophy, tardive","type":"related"}],"termid":"MONDO:0010870","xrefs":{"Monarch":{"xref_id":"0010870"}}}


id: PBO:0004726
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial PPR repeat protein Ppr1","termid":"PBO:0004726"}


id: MONDO:0020604
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"X-linked dominant form of disease.","definition_xrefs":["MONDO:patterns/x_linked"],"direct_ancestors":[{"relation_name":"is_a","term_name":"X-linked disease","termid":"MONDO:0000425"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"X-linked dominant disease","secondary_identifiers":["UMLS:C5566661","MEDGEN:1798084","DOID:0080009"],"termid":"MONDO:0020604","xrefs":{"Monarch":{"xref_id":"0020604"}}}


id: PBO:0077227
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TMC3 antisense RNA 1","termid":"PBO:0077227"}


id: PBO:0072095
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S12 pseudogene 26","termid":"PBO:0072095"}


id: MONDO:0045030
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"diarrheal disease","termid":"MONDO:0001673"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"non-infectious diarrheal disease","secondary_identifiers":["MEDGEN:540680","SCTID:69980003","UMLS:C0267436"],"synonyms":[{"name":"non-infective diarrhea","type":"exact"},{"name":"non-infective diarrhoea","type":"exact"},{"name":"presumed non-infectious diarrhea","type":"related"},{"name":"presumed non-infectious diarrhoea","type":"related"}],"termid":"MONDO:0045030","xrefs":{"Monarch":{"xref_id":"0045030"}}}


id: PBO:0028492
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-mislocalized_post-anaphase_array","termid":"PBO:0028492"}


id: PBO:0113338
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein of unknown function; proposed role as basic amino acid permease based on phylogeny; targeted to vacuole via AP-3 pathway; physical interaction with Atg27p suggests possible role in autophagy; non-essential gene","termid":"PBO:0113338"}


id: PR:P87118
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An inorganic pyrophosphatase that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO00572"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"inorganic pyrophosphatase C3A12.02 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC3A12.02","secondary_identifiers":["UniProtKB:P87118"],"synonyms":[{"name":"PPase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-PPA1","type":"exact"},{"name":"pyrophosphate phosphohydrolase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:P87118"}


id: FYPO:0001903
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell population phenotype in which the septation index is normal (i.e. indistinguishable from wild type). The septation index is the proportion of the population undergoing septation at any given time, and is usually around 10% (varying between 7-15%) for vegetatively growing wild type cell populations, and less for stationary populations.","definition_xrefs":["PomBase:vw","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell population phenotype","termid":"FYPO:0000003"},{"relation_name":"is_a","term_name":"normal phenotype","termid":"FYPO:0000257"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000003","FYPO:0000257"],"is_obsolete":false,"name":"normal septation index","synonyms":[{"name":"normal septation","type":"related"}],"termid":"FYPO:0001903"}


id: GO:0003866
data:
  {"annotated_genes":["SJAG_00337"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[74063],"is_not":false,"summary":null,"term":"GO:0003866"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: 3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate.","definition_xrefs":["EC:2.5.1.19","RHEA:21256"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transferase activity, transferring alkyl or aryl (other than methyl) groups","termid":"GO:0016765"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00337":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016765"}],"interesting_parent_ids":["GO:0016765","GO:0003674","GO:0016740","GO:0003824"],"is_obsolete":false,"name":"3-phosphoshikimate 1-carboxyvinyltransferase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["KEGG_REACTION:R03460","MetaCyc:2.5.1.19-RXN"],"synonyms":[{"name":"3-enol-pyruvoylshikimate-5-phosphate synthase activity","type":"related"},{"name":"5-enolpyruvylshikimate-3-phosphate synthase activity","type":"related"},{"name":"EPSP synthase activity","type":"related"},{"name":"phosphoenolpyruvate:3-phosphoshikimate 5-O-(1-carboxyvinyl)-transferase activity","type":"related"}],"termid":"GO:0003866","terms_by_termid":{"GO:0003866":null}}


id: FYPO:0003024
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is abnormal. Synapsis is the process in which the side by side pairing and physical juxtaposition of homologous chromosomes is established and maintained. Pairing may be assayed globally or at one or more specific loci.","definition_xrefs":["GO:0007129","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal homologous chromosome segregation","termid":"FYPO:0004159"},{"relation_name":"is_a","term_name":"abnormal meiotic chromosome organization","termid":"FYPO:0006759"},{"relation_name":"is_a","term_name":"abnormal cellular process during meiotic cell cycle","termid":"FYPO:0007260"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000641"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"part_of","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"part_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000641","FYPO:0001985","FYPO:0005447","FYPO:0000631"],"is_obsolete":false,"name":"abnormal homologous chromosome pairing","synonyms":[{"name":"abnormal homologous chromosome pairing at meiosis","type":"exact"},{"name":"abnormal synapsis","type":"exact"}],"termid":"FYPO:0003024"}


id: MONDO:0007321
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Autosomal dominant form of chondrodysplasia punctata.","definition_xrefs":["MONDO:patterns/autosomal_dominant"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant disease","termid":"MONDO:0000426"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"non-rhizomelic chondrodysplasia punctata","termid":"MONDO:0015775"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426"],"is_obsolete":false,"name":"autosomal dominant chondrodysplasia punctata","secondary_identifiers":["DOID:0060293","MEDGEN:303176","MONDO:0022728","GARD:1298","OMIM:118650","UMLS:C1442935","MESH:C563248","Orphanet:79344"],"synonyms":[{"name":"chondrodysplasia punctata Sheffield type","type":"exact"},{"name":"chondrodysplasia punctata due to vitamin K deficiency","type":"related"},{"name":"chondrodysplasia punctata due to warfarin teratogenicity","type":"related"},{"name":"chondrodysplasia punctata, Sheffield type","type":"exact"},{"name":"chondrodysplasia punctata, autosomal dominant","type":"exact"}],"termid":"MONDO:0007321","xrefs":{"Monarch":{"xref_id":"0007321"}}}


id: PBO:0076632
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TBL1XR1 antisense RNA 1","termid":"PBO:0076632"}


id: PBO:0062560
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 10 subfamily A member 7","termid":"PBO:0062560"}


id: MOD:01920
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-histidine residue to 3-hydroxy-L-histidine.","definition_xrefs":["PubMed:21251231","ChEBI:138021","RESID:AA0580"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydroxylated residue","termid":"MOD:00677"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3-hydroxy-L-histidine","synonyms":[{"name":"(2S)-2-amino-3-hydroxy-3-(1H-imidazol-4-yl)propanoic acid","type":"exact"},{"name":"3-hydroxy-L-histidine","type":"exact"},{"name":"MOD_RES (3S)-3-hydroxyhistidine","type":"exact"}],"termid":"MOD:01920"}


id: GO:0097339
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which glycolate is transported across a membrane. Glycolate is the anion of hydroxyethanoic acid (glycolic acid).","definition_xrefs":["PMID:11785976","PMID:11283302","GOC:am"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glycolate transport","termid":"GO:1900866"},{"relation_name":"is_a","term_name":"carboxylic acid transmembrane transport","termid":"GO:1905039"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0051179","GO:0008150","GO:0055085","GO:0006810"],"is_obsolete":false,"name":"glycolate transmembrane transport","synonyms":[{"name":"glycolate membrane transport","type":"exact"}],"termid":"GO:0097339"}


id: PBO:0034373
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-overlaps_sequence_of","termid":"PBO:0034373"}


id: GO:0070631
data:
  {"annotated_genes":["SJAG_03200","SJAG_02332","SJAG_04558","SJAG_01422","SJAG_01460","SJAG_05196"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[113289,104643,91944,102422,105277,114702],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140480"}]},"cv_name":"biological_process","definition":"Any process in which a spindle pole body is transported to, or maintained in, a specific location. A spindle pole body is a type of microtubule organizing center found in fungal cells.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular localization","termid":"GO:0051641"},{"relation_name":"is_a","term_name":"microtubule organizing center localization","termid":"GO:0061842"}],"gene_count":6,"genes_by_uniquename":{"SJAG_01422":null,"SJAG_01460":null,"SJAG_02332":null,"SJAG_03200":null,"SJAG_04558":null,"SJAG_05196":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0008150","GO:0051179"],"is_obsolete":false,"name":"spindle pole body localization","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["GO:1990944","GO:0071790"],"synonyms":[{"name":"maintenance of spindle pole body localization","type":"narrow"},{"name":"spindle pole body localisation","type":"exact"}],"termid":"GO:0070631","terms_by_termid":{"GO:0140480":null}}


id: MONDO:1012957
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Cerebellar ataxia that occurs in dogs.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cerebellar degeneration, dog","termid":"MONDO:1011016"},{"relation_name":"is_a","term_name":"cerebellar ataxia, non-human animal","termid":"MONDO:1012956"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cerebellar ataxia, dog","termid":"MONDO:1012957","xrefs":{"Monarch":{"xref_id":"1012957"}}}


id: GO:0004039
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: H2O + 3 H+ + urea-1-carboxylate = 2 CO2 + 2 NH4.","definition_xrefs":["EC:3.5.1.54","RHEA:19029"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides","termid":"GO:0016811"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016810"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"}],"interesting_parent_ids":["GO:0016810","GO:0016787","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"allophanate hydrolase activity","secondary_identifiers":["MetaCyc:ALLOPHANATE-HYDROLASE-RXN","KEGG_REACTION:R00005","UM-BBD_reactionID:r0848"],"synonyms":[{"name":"allophanate lyase activity","type":"related"},{"name":"urea-1-carboxylate amidohydrolase activity","type":"related"}],"termid":"GO:0004039"}


id: FYPO:0003524
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cytoskeleton organization is abnormal at one or both cell tips.","definition_xrefs":["GO:0030036","PomBase:mah","PMID:24954052"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal actin cytoskeleton organization during vegetative growth","termid":"FYPO:0000801"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0004803"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0005447","FYPO:0001985","FYPO:0004803","FYPO:0000002"],"is_obsolete":false,"name":"abnormal actin cytoskeleton organization at cell tip","synonyms":[{"name":"abnormal actin cytoskeleton organisation at cell tip","type":"exact"},{"name":"abnormal actin cytoskeleton organization at cell end","type":"exact"},{"name":"abnormal actin cytoskeleton organization at cell tip during mitotic cell cycle","type":"related"},{"name":"abnormal actin cytoskeleton organization at cell tip during vegetative growth","type":"exact"}],"termid":"FYPO:0003524"}


id: PBO:0062102
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 4 subfamily B member 2 pseudogene","termid":"PBO:0062102"}


id: PBO:0012526
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-regulates_o_results_in_development_of","termid":"PBO:0012526"}


id: PBO:0049576
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"H2B.W histone 4, pseudogene","termid":"PBO:0049576"}


id: MONDO:0011669
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare syndrome including neonatal and infantile hypotonia and failure to thrive, cystinuria type 1 and nephrolithiasis, growth retardation due to growth hormone deficiency, and minor facial dysmorphism.","definition_xrefs":["Orphanet:163690"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"inherited renal tubular disease","termid":"MONDO:0015962"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"inborn mitochondrial metabolism disorder","termid":"MONDO:0004069"},{"relation_name":"is_a","term_name":"partial deletion of the short arm of chromosome 2","termid":"MONDO:0016884"},{"relation_name":"is_a","term_name":"inborn disorder of amino acid transport","termid":"MONDO:0019216"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0004736"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0004069","MONDO:0004736"],"is_obsolete":false,"name":"hypotonia-cystinuria syndrome","secondary_identifiers":["MEDGEN:341133","DOID:0060858","UMLS:C1848030","icd11.foundation:1852649756","GARD:16998","icd11.foundation:1742079513","SCTID:721173005","OMIM:606407","MESH:C564710","Orphanet:238517"],"synonyms":[{"name":"HCS","type":"exact"},{"name":"cystinuria with mitochondrial disease","type":"exact"},{"name":"homozygous 2P16 deletion syndrome","type":"related"},{"name":"homozygous 2P16 deletion syndrome, formerly","type":"related"},{"name":"homozygous 2P21 deletion syndrome","type":"related"},{"name":"hypotonia-cystinuria syndrome","type":"exact"},{"name":"hypotonia-cystinuria syndrome type 1","type":"exact"},{"name":"hypotonia-cystinuria type 1 syndrome","type":"exact"}],"termid":"MONDO:0011669","xrefs":{"Monarch":{"xref_id":"0011669"}}}


id: SO:0000600
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","gene_count":0,"genotype_count":0,"name":"OBSOLETE SO:0000600 edited_by_A_to_I_substitution (obsolete SO:0000600)","termid":"SO:0000600"}


id: MONDO:0006313
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign, mucus-filled cervical cyst that occurs when mucus-secreting columnar epithelial cells are covered with squamous epithelium.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"uterine cervix neoplasm","termid":"MONDO:0021230"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nabothian cyst","secondary_identifiers":["UMLS:C0027269","EFO:1000390","icd11.foundation:1329172977","Wikipedia:Nabothian_cyst","MEDGEN:6510","SCTID:24565001","NCIT:C34835"],"termid":"MONDO:0006313","xrefs":{"Monarch":{"xref_id":"0006313"}}}


id: PBO:0073481
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serum/glucocorticoid regulated kinase 2","termid":"PBO:0073481"}


id: MONDO:0023563
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Hermansky-Pudlak syndrome","termid":"MONDO:0019312"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"},{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0005093","MONDO:0005570"],"is_obsolete":false,"name":"Kotzot-Richter syndrome","secondary_identifiers":["GARD:3134","OMIM:203285","UMLS:C2931399","MESH:C537025","MEDGEN:419793"],"synonyms":[{"name":"albinism with immune and hematologic defects","type":"related"},{"name":"oculocutaneous albinism, immunodeficiency, haematological disorders, and minor anomalies","type":"related"},{"name":"oculocutaneous albinism, immunodeficiency, hematological disorders, and minor anomalies","type":"related"}],"termid":"MONDO:0023563","xrefs":{"Monarch":{"xref_id":"0023563"}}}


id: PBO:0083326
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps ORFs PTC2/YER089C and YER088W-B","termid":"PBO:0083326"}


id: MONDO:0009617
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any autosomal recessive primary microcephaly in which the cause of the disease is a mutation in the MCPH1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive primary microcephaly","termid":"MONDO:0016660"},{"relation_name":"is_a","term_name":"microcephaly with intellectual disability","termid":"MONDO:0100200"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0700092"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0700092","MONDO:0006025"],"is_obsolete":false,"name":"microcephaly 1, primary, autosomal recessive","secondary_identifiers":["UMLS:C1855081","MESH:C565384","GARD:15198","OMIM:251200","DOID:0070285","Orphanet:52183","MEDGEN:344415"],"synonyms":[{"name":"MCPH1","type":"related"},{"name":"MCPH1 autosomal recessive primary microcephaly","type":"exact"},{"name":"PCC syndrome","type":"related"},{"name":"autosomal recessive primary microcephaly caused by mutation in MCPH1","type":"exact"},{"name":"microcephaly 1, primary, autosomal recessive","type":"exact"},{"name":"premature chromosome condensation syndrome","type":"related"},{"name":"premature chromosome condensation with microcephaly and intellectual disability","type":"related"},{"name":"premature chromosome condensation with microcephaly and mental retardation","type":"related"}],"termid":"MONDO:0009617","xrefs":{"Monarch":{"xref_id":"0009617"}}}


id: PBO:0064425
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"patatin like phospholipase domain containing 3","termid":"PBO:0064425"}


id: GO:0002872
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell tolerance induction.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of tolerance induction","termid":"GO:0002644"},{"relation_name":"is_a","term_name":"regulation of acute inflammatory response","termid":"GO:0002673"},{"relation_name":"is_a","term_name":"regulation of natural killer cell tolerance induction","termid":"GO:0002871"},{"relation_name":"negatively_regulates","term_name":"natural killer cell tolerance induction","termid":"GO:0002519"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of natural killer cell tolerance induction","synonyms":[{"name":"down regulation of natural killer cell tolerance induction","type":"exact"},{"name":"down-regulation of natural killer cell tolerance induction","type":"exact"},{"name":"downregulation of natural killer cell tolerance induction","type":"exact"},{"name":"inhibition of natural killer cell tolerance induction","type":"narrow"},{"name":"negative regulation of NK cell tolerance induction","type":"exact"}],"termid":"GO:0002872"}


id: GO:0004154
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: a 7,8-dihydropteridine compound + O2 = an oxidized 7,8-dihydropteridine compound + H2O2. Specific substrates and their fully oxidized products include: 7,8-dihydropteridin/pterin, 7,8-dihydrobiopterin/biopterin, 7,8-dihydroxanthopterin/xanthopterin and sepiapterin/oxidized sepiapterin.","definition_xrefs":["PMID:38786926","GOC:sjm","PMID:1745247","PMID:6815189"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor","termid":"GO:0016647"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"dihydropterin oxidase activity","termid":"GO:0004154"}


id: PBO:0080086
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin specific peptidase 47","termid":"PBO:0080086"}


id: GO:0160264
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: histone H1 L-asparagine [positions 76 and 77] + H2O = histone H1 L-aspartate [positions 76 and 77] + NH4+.","definition_xrefs":["PMID:40240600"],"direct_ancestors":[{"relation_name":"is_a","term_name":"histone H1 asparagine deamidase activity","termid":"GO:0160261"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0016810"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016787","GO:0016810","GO:0140096"],"is_obsolete":false,"name":"histone H1N76/N77 asparagine deamidase activity","termid":"GO:0160264"}


id: GO:0043583
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the ear over time, from its formation to the mature structure. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals.","definition_xrefs":["GOC:jl","ISBN:0192801023"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sensory organ development","termid":"GO:0007423"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"ear development","synonyms":[{"name":"hearing organ development","type":"exact"}],"termid":"GO:0043583"}


id: MONDO:0004994
data:
  {"annotated_genes":["SJAG_04621","SJAG_04231","SJAG_02611","SJAG_00547","SJAG_02431","SJAG_02536","SJAG_03077","SJAG_02785","SJAG_04567","SJAG_MIT13","SJAG_04553","SJAG_03453","SJAG_04397","SJAG_02923","SJAG_03145","SJAG_03126","SJAG_MIT03","SJAG_00930","SJAG_02229","SJAG_03703","SJAG_02131","SJAG_02342","SJAG_05199","SJAG_00993","SJAG_01139","SJAG_01665","SJAG_01240","SJAG_02919","SJAG_01671","SJAG_01322","SJAG_00228","SJAG_03824","SJAG_03815","SJAG_MIT15","SJAG_01209","SJAG_01754","SJAG_01181"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87605],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:8000015"},{"annotations":[87140],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011451"},{"annotations":[86893],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014051"},{"annotations":[86872],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014667"},{"annotations":[86870],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014668"},{"annotations":[86792],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014112"},{"annotations":[86793,86794,86795],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014113"},{"annotations":[86799,86798,86800],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014114"},{"annotations":[88059],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0032592"},{"annotations":[88345,88344],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0030300"},{"annotations":[87337],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0859358"},{"annotations":[88159],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0957545"},{"annotations":[88126],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0030330"},{"annotations":[87478],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012557"},{"annotations":[87665,87666],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008409"},{"annotations":[86971],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009026"},{"annotations":[87979],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012808"},{"annotations":[88249,88250],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013198"},{"annotations":[88850],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013339"},{"annotations":[86929,86930,86928],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014073"},{"annotations":[87959],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013261"},{"annotations":[87961,87960],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013262"},{"annotations":[87469],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012556"},{"annotations":[87010,87011],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009290"},{"annotations":[86949,86950],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008647"},{"annotations":[88237],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012112"},{"annotations":[87999],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012799"},{"annotations":[88246,88247],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013197"},{"annotations":[87125],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010946"},{"annotations":[88242],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012111"},{"annotations":[87331,87330,87329],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010788"},{"annotations":[88025],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009867"},{"annotations":[89075,89076,89074],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008104"},{"annotations":[87558],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0033669"},{"annotations":[88441],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012371"},{"annotations":[88232],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013186"},{"annotations":[87295,87296],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0054588"},{"annotations":[89009],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013968"},{"annotations":[87813],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008685"}]},"cv_name":"mondo","definition":"A disease of the heart muscle or myocardium proper. Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive.","definition_xrefs":["NCIT:C34830"],"direct_ancestors":[{"relation_name":"is_a","term_name":"muscle tissue disorder","termid":"MONDO:0003939"},{"relation_name":"is_a","term_name":"heart disorder","termid":"MONDO:0005267"}],"gene_count":37,"genes_by_uniquename":{"SJAG_00228":null,"SJAG_00547":null,"SJAG_00930":null,"SJAG_00993":null,"SJAG_01139":null,"SJAG_01181":null,"SJAG_01209":null,"SJAG_01240":null,"SJAG_01322":null,"SJAG_01665":null,"SJAG_01671":null,"SJAG_01754":null,"SJAG_02131":null,"SJAG_02229":null,"SJAG_02342":null,"SJAG_02431":null,"SJAG_02536":null,"SJAG_02611":null,"SJAG_02785":null,"SJAG_02919":null,"SJAG_02923":null,"SJAG_03077":null,"SJAG_03126":null,"SJAG_03145":null,"SJAG_03453":null,"SJAG_03703":null,"SJAG_03815":null,"SJAG_03824":null,"SJAG_04231":null,"SJAG_04397":null,"SJAG_04553":null,"SJAG_04567":null,"SJAG_04621":null,"SJAG_05199":null,"SJAG_MIT03":null,"SJAG_MIT13":null,"SJAG_MIT15":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"cardiomyopathy","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["DOID:0050700","MESH:D009202","icd11.foundation:282225286","ICD9:425.4","SCTID:57809008","ICD9:425.9","Orphanet:167848","UMLS:C0878544","ICD9:425","MEDGEN:209232","EFO:0000318","ICD10CM:I42","MedDRA:10007636","SCTID:85898001"],"synonyms":[{"name":"Cardiomyopathies","type":"exact"},{"name":"cardiomyopathy","type":"exact"}],"termid":"MONDO:0004994","terms_by_termid":{"MONDO:0008104":null,"MONDO:0008409":null,"MONDO:0008647":null,"MONDO:0008685":null,"MONDO:0009026":null,"MONDO:0009290":null,"MONDO:0009867":null,"MONDO:0010788":null,"MONDO:0010946":null,"MONDO:0011451":null,"MONDO:0012111":null,"MONDO:0012112":null,"MONDO:0012371":null,"MONDO:0012556":null,"MONDO:0012557":null,"MONDO:0012799":null,"MONDO:0012808":null,"MONDO:0013186":null,"MONDO:0013197":null,"MONDO:0013198":null,"MONDO:0013261":null,"MONDO:0013262":null,"MONDO:0013339":null,"MONDO:0013968":null,"MONDO:0014051":null,"MONDO:0014073":null,"MONDO:0014112":null,"MONDO:0014113":null,"MONDO:0014114":null,"MONDO:0014667":null,"MONDO:0014668":null,"MONDO:0030300":null,"MONDO:0030330":null,"MONDO:0032592":null,"MONDO:0033669":null,"MONDO:0054588":null,"MONDO:0859358":null,"MONDO:0957545":null,"MONDO:8000015":null},"xrefs":{"Monarch":{"xref_id":"0004994"}}}


id: MONDO:0044995
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A disease or disorder that involves the parasympathetic nervous system.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autonomic nervous system disorder","termid":"MONDO:0001292"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"parasympathetic nervous system disorder","secondary_identifiers":["MEDGEN:148205","SCTID:46091002","UMLS:C0750945"],"synonyms":[{"name":"disease of parasympathetic nervous system","type":"exact"},{"name":"disease or disorder of parasympathetic nervous system","type":"exact"},{"name":"disorder of parasympathetic nervous system","type":"exact"},{"name":"parasympathetic nervous system disease","type":"exact"},{"name":"parasympathetic nervous system disease or disorder","type":"exact"}],"termid":"MONDO:0044995","xrefs":{"Monarch":{"xref_id":"0044995"}}}


id: PBO:0044151
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CTD nuclear envelope phosphatase 1","termid":"PBO:0044151"}


id: PBO:0091261
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small non-coding RNA, poly(A)-bearing, not reproduced","termid":"PBO:0091261"}


id: GO:0061741
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chaperone-mediated protein transport process in which a protein that is bound to a chaperone and a lysosomal receptor is unfolded and transported into the lysosome as part of chaperone-mediated autophagy.","definition_xrefs":["GOC:autophagy","GOC:PARL","GOC:pad","GOC:dph","PMID:22748206"],"gene_count":0,"genotype_count":0,"name":"obsolete chaperone-mediated protein transport involved in chaperone-mediated autophagy (obsolete GO:0061741)","termid":"GO:0061741"}


id: MONDO:1011647
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"cardiovascular disorder, non-human animal","termid":"MONDO:1011306"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chronic valvular disease, non-human animal","secondary_identifiers":["OMIA:001246"],"termid":"MONDO:1011647","xrefs":{"Monarch":{"xref_id":"1011647"}}}


id: PBO:0081662
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 585A","termid":"PBO:0081662"}


id: MONDO:0004786
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Cholangitis that is persistent and long-standing.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cholangitis","termid":"MONDO:0004789"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002515"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0002515"],"is_obsolete":false,"name":"chronic cholangitis","secondary_identifiers":["UMLS:C0267918","DOID:9439","NCIT:C35335","MEDGEN:82765","SCTID:71912000"],"synonyms":[{"name":"cholangitis, chronic","type":"exact"}],"termid":"MONDO:0004786","xrefs":{"Monarch":{"xref_id":"0004786"}}}


id: MONDO:0022504
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"arthrogryposis spinal muscular atrophy","termid":"MONDO:0022504","xrefs":{"Monarch":{"xref_id":"0022504"}}}


id: GO:0045481
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 6-endo-hydroxycineole + NAD+ = 6-oxocineole + H+ + NADH.","definition_xrefs":["RHEA:11736","EC:1.1.1.241"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"6-endo-hydroxycineole dehydrogenase activity","secondary_identifiers":["MetaCyc:6-ENDO-HYDROXYCINEOLE-DEHYDROGENASE-RXN","KEGG_REACTION:R02994"],"synonyms":[{"name":"6-endo-hydroxycineole:NAD+ 6-oxidoreductase activity","type":"related"}],"termid":"GO:0045481"}


id: MOD:01580
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces the O4'-hydrogen atom of a tyrosine residue with the Applied Biosystems iTRAQ8plex-121 reporter+balance group.","definition_xrefs":["Unimod:731#Y"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified L-tyrosine residue","termid":"MOD:00919"},{"relation_name":"is_a","term_name":"iTRAQ8plex-121 reporter+balance reagent acylated residue","termid":"MOD:01577"},{"relation_name":"is_a","term_name":"iTRAQ8plex reporter+balance reagent O-acylated residue","termid":"MOD:01714"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"iTRAQ8plex-121 reporter+balance reagent O4'-acylated tyrosine","synonyms":[{"name":"(4-methylpiperazin-1-yl)acetyl","type":"exact"},{"name":"Accurate mass for 115, 118, 119 & 121","type":"related"},{"name":"Applied Biosystems iTRAQ(TM) multiplexed quantitation chemistry","type":"related"},{"name":"iTRAQ8plex:13C(6)15N(2)","type":"related"}],"termid":"MOD:01580"}


id: GO:0047567
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 3-methyloxindole + NADP+ = 3-methyleneoxindole + H+ + NADPH.","definition_xrefs":["RHEA:20257","EC:1.3.1.17"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor","termid":"GO:0016628"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"3-methyleneoxindole reductase activity","secondary_identifiers":["MetaCyc:3-METHYLENEOXINDOLE-REDUCTASE-RXN","KEGG_REACTION:R03930"],"synonyms":[{"name":"3-methyl-1,3-dihydroindol-2-one:NADP+ oxidoreductase activity","type":"related"},{"name":"3-methyloxindole:NADP+ oxidoreductase activity","type":"related"}],"termid":"GO:0047567"}


id: PATO:0002462
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A composition quality inhering in an bearer by virtue of the bearer's consisting of collagen.","definition_xrefs":["PATOC:WD"],"direct_ancestors":[{"relation_name":"is_a","term_name":"composition","termid":"PATO:0000025"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"collagenous","termid":"PATO:0002462"}


id: FYPO:0004136
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 in telomeric regions does not occur.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished histone H3-K9 methylation at telomere during vegetative growth","termid":"FYPO:0002820"},{"relation_name":"is_a","term_name":"abolished histone H3-K9 dimethylation during vegetative growth","termid":"FYPO:0007886"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0002494"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0002274","FYPO:0001985","FYPO:0002494","FYPO:0005447","FYPO:0001320"],"is_obsolete":false,"name":"abolished histone H3-K9 dimethylation at telomere during vegetative growth","synonyms":[{"name":"abolished histone H3 K9 dimethylation at telomere during vegetative growth","type":"exact"},{"name":"abolished histone H3-K9 dimethylation at telomere during mitotic cell cycle","type":"related"},{"name":"abolished histone H3-K9 dimethylation at telomeric region during vegetative growth","type":"exact"},{"name":"abolished histone H3K9me2 at telomere during vegetative growth","type":"exact"},{"name":"abolished histone lysine H3 K9 dimethylation at telomere during vegetative growth","type":"exact"},{"name":"abolished telomeric histone H3-K9 dimethylation during vegetative growth","type":"exact"},{"name":"histone H3-K9 dimethylation abolished at telomere during vegetative growth","type":"exact"},{"name":"histone H3-K9 dimethylation absent at telomere during vegetative growth","type":"exact"}],"termid":"FYPO:0004136"}


id: PBO:0029429
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_RNA_level_during_cellular_response_to_heat","termid":"PBO:0029429"}


id: PBO:0072590
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal RNA processing 36","termid":"PBO:0072590"}


id: GO:0072155
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The orderly movement of epithelial cells within a renal tubule that contributes to nephron tubule morphogenesis.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epithelial cell migration","termid":"GO:0010631"},{"relation_name":"is_a","term_name":"cell migration involved in kidney development","termid":"GO:0035787"},{"relation_name":"part_of","term_name":"nephron tubule morphogenesis","termid":"GO:0072078"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"epithelial cell migration involved in nephron tubule morphogenesis","termid":"GO:0072155"}


id: PBO:0058046
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4267","termid":"PBO:0058046"}


id: PBO:0085768
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication","termid":"PBO:0085768"}


id: PBO:0084843
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial ribosomal protein of the large subunit; has similarity to E. coli L4 ribosomal protein and human mitoribosomal MRP-L4 protein; essential for viability, unlike most other mitoribosomal proteins","termid":"PBO:0084843"}


id: GO:0006622
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process of directing proteins towards the lysosome using signals contained within the protein.","definition_xrefs":["GOC:curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein targeting to vacuole","termid":"GO:0006623"},{"relation_name":"is_a","term_name":"lysosomal transport","termid":"GO:0007041"},{"relation_name":"is_a","term_name":"protein localization to lysosome","termid":"GO:0061462"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006605"}],"interesting_parent_ids":["GO:0051179","GO:0006605","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"protein targeting to lysosome","synonyms":[{"name":"protein-lysosome targeting","type":"exact"}],"termid":"GO:0006622"}


id: PBO:0083647
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Elongin A; F-box protein that forms a heterodimer with Elc1p and is required for ubiquitin-dependent degradation of the RNA Polymerase II subunit Rpo21p; subunit of the Elongin-Cullin-Socs (ECS) ligase complex","termid":"PBO:0083647"}


id: GO:0016971
data:
  {"annotated_genes":["SJAG_03992","SJAG_01647"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[58258,65553],"is_not":false,"summary":null,"term":"GO:0016971"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: [protein]-dithiol + O2 = [protein]-disulfide + H2O2 using FAD as a cofactor, leading to formation of disulfide bridges in proteins.","definition_xrefs":["PMID:10899311","PMID:19679655","PMID:35495482"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-disulfide reductase activity","termid":"GO:0015035"},{"relation_name":"is_a","term_name":"thiol oxidase activity","termid":"GO:0016972"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01647":null,"SJAG_03992":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0015036"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0015036","GO:0140096","GO:0016491","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"flavin-dependent sulfhydryl oxidase activity","references_by_uniquename":{"GO_REF:0000002":null},"secondary_identifiers":["RHEA:59116"],"synonyms":[{"name":"flavin-linked sulfhydryl oxidase activity","type":"exact"}],"termid":"GO:0016971","terms_by_termid":{"GO:0016971":null}}


id: PBO:0091978
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"wtf meiotic drive poison Wtf19","termid":"PBO:0091978"}


id: FYPO:0007913
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which organelle localization is normal.","direct_ancestors":[{"relation_name":"is_a","term_name":"normal cellular process during vegetative growth","termid":"FYPO:0001319"},{"relation_name":"is_a","term_name":"localization phenotype during vegetative growth","termid":"FYPO:0001337"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001312"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0000002","FYPO:0000138","FYPO:0001320","FYPO:0001312"],"is_obsolete":false,"name":"normal organelle localization","termid":"FYPO:0007913"}


id: PBO:0073942
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 18 member B1","termid":"PBO:0073942"}


id: GO:1902532
data:
  {"annotated_genes":["SJAG_01679","SJAG_03185","SJAG_00883","SJAG_01253","SJAG_04206","SJAG_06270","SJAG_00457","SJAG_02392","SJAG_04249","SJAG_00169","SJAG_03486","SJAG_00875","SJAG_00991","SJAG_00526","SJAG_00293","SJAG_04825","SJAG_01297","SJAG_02389","SJAG_00229","SJAG_03681","SJAG_04462","SJAG_03508","SJAG_02000","SJAG_03678","SJAG_04910","SJAG_00824","SJAG_02765","SJAG_03126","SJAG_02169","SJAG_01983","SJAG_00209","SJAG_02858","SJAG_03355","SJAG_03501","SJAG_01386","SJAG_05346","SJAG_04259","SJAG_04455","SJAG_01184","SJAG_00642","SJAG_03893","SJAG_02233","SJAG_03072","SJAG_03089","SJAG_03263","SJAG_02013","SJAG_02451","SJAG_03353","SJAG_01142","SJAG_02379","SJAG_00289","SJAG_02231","SJAG_05000","SJAG_04943","SJAG_01790","SJAG_01114","SJAG_03974","SJAG_03592","SJAG_02336","SJAG_02514","SJAG_04522","SJAG_03799","SJAG_00975","SJAG_01464"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[92535,116131,117762,113815,115643,105713,110094,101405,109066],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1902426"},{"annotations":[117989,102817],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0106057"},{"annotations":[101254,109447,105621,108879,120196,97667],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903138"},{"annotations":[96010],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140499"},{"annotations":[93482,97789,120197,96851,118945,101256],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903753"},{"annotations":[90021,108972],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0180040"},{"annotations":[74066],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0046580"},{"annotations":[73283],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0035024"},{"annotations":[74647,103092,109377,93550,106873,92539,112017,94742,97454,101407,108934,109067,95270,117765,94657],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031030"},{"annotations":[93053,107726,113567],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:2000639"},{"annotations":[74910],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0032007"},{"annotations":[111521,116437,117990,75289,81668,118345,115835,118908,62916,108984,120100,95141,97916,119907,75396,103276,100692,111114,101389,104835,115017,89836,106963],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1904262"},{"annotations":[118136],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903940"}]},"cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction.","definition_xrefs":["GOC:tb","GOC:signaling","GOC:TermGenie","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of signal transduction","termid":"GO:0009968"},{"relation_name":"is_a","term_name":"regulation of intracellular signal transduction","termid":"GO:1902531"},{"relation_name":"negatively_regulates","term_name":"intracellular signal transduction","termid":"GO:0035556"}],"gene_count":64,"genes_by_uniquename":{"SJAG_00169":null,"SJAG_00209":null,"SJAG_00229":null,"SJAG_00289":null,"SJAG_00293":null,"SJAG_00457":null,"SJAG_00526":null,"SJAG_00642":null,"SJAG_00824":null,"SJAG_00875":null,"SJAG_00883":null,"SJAG_00975":null,"SJAG_00991":null,"SJAG_01114":null,"SJAG_01142":null,"SJAG_01184":null,"SJAG_01253":null,"SJAG_01297":null,"SJAG_01386":null,"SJAG_01464":null,"SJAG_01679":null,"SJAG_01790":null,"SJAG_01983":null,"SJAG_02000":null,"SJAG_02013":null,"SJAG_02169":null,"SJAG_02231":null,"SJAG_02233":null,"SJAG_02336":null,"SJAG_02379":null,"SJAG_02389":null,"SJAG_02392":null,"SJAG_02451":null,"SJAG_02514":null,"SJAG_02765":null,"SJAG_02858":null,"SJAG_03072":null,"SJAG_03089":null,"SJAG_03126":null,"SJAG_03185":null,"SJAG_03263":null,"SJAG_03353":null,"SJAG_03355":null,"SJAG_03486":null,"SJAG_03501":null,"SJAG_03508":null,"SJAG_03592":null,"SJAG_03678":null,"SJAG_03681":null,"SJAG_03799":null,"SJAG_03893":null,"SJAG_03974":null,"SJAG_04206":null,"SJAG_04249":null,"SJAG_04259":null,"SJAG_04455":null,"SJAG_04462":null,"SJAG_04522":null,"SJAG_04825":null,"SJAG_04910":null,"SJAG_04943":null,"SJAG_05000":null,"SJAG_05346":null,"SJAG_06270":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"negative regulation of intracellular signal transduction","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null,"GO_REF:0000117":null},"secondary_identifiers":["GO:0010741"],"synonyms":[{"name":"down regulation of intracellular signal transduction","type":"exact"},{"name":"down regulation of intracellular signal transduction pathway","type":"narrow"},{"name":"down regulation of intracellular signaling cascade","type":"narrow"},{"name":"down regulation of intracellular signaling chain","type":"exact"},{"name":"down regulation of intracellular signaling pathway","type":"related"},{"name":"down regulation of signal transduction via intracellular signaling cascade","type":"related"},{"name":"down regulation of signal transmission via intracellular cascade","type":"narrow"},{"name":"down-regulation of intracellular signal transduction","type":"exact"},{"name":"down-regulation of intracellular signal transduction pathway","type":"narrow"},{"name":"down-regulation of intracellular signaling cascade","type":"related"},{"name":"down-regulation of intracellular signaling chain","type":"exact"},{"name":"down-regulation of intracellular signaling pathway","type":"related"},{"name":"down-regulation of signal transduction via intracellular signaling cascade","type":"related"},{"name":"down-regulation of signal transmission via intracellular cascade","type":"related"},{"name":"downregulation of intracellular signal transduction","type":"exact"},{"name":"downregulation of intracellular signal transduction pathway","type":"narrow"},{"name":"downregulation of intracellular signaling cascade","type":"narrow"},{"name":"downregulation of intracellular signaling chain","type":"exact"},{"name":"downregulation of intracellular signaling pathway","type":"related"},{"name":"downregulation of signal transduction via intracellular signaling cascade","type":"related"},{"name":"downregulation of signal transmission via intracellular cascade","type":"narrow"},{"name":"inhibition of intracellular signal transduction","type":"narrow"},{"name":"inhibition of intracellular signal transduction pathway","type":"narrow"},{"name":"inhibition of intracellular signaling cascade","type":"narrow"},{"name":"inhibition of intracellular signaling chain","type":"narrow"},{"name":"inhibition of intracellular signaling pathway","type":"related"},{"name":"inhibition of signal transduction via intracellular signaling cascade","type":"related"},{"name":"inhibition of signal transmission via intracellular cascade","type":"narrow"},{"name":"negative regulation of intracellular protein kinase cascade","type":"exact"},{"name":"negative regulation of intracellular signal transduction pathway","type":"narrow"},{"name":"negative regulation of intracellular signaling cascade","type":"exact"},{"name":"negative regulation of intracellular signaling chain","type":"exact"},{"name":"negative regulation of intracellular signaling pathway","type":"related"},{"name":"negative regulation of signal transduction via intracellular signaling cascade","type":"related"},{"name":"negative regulation of signal transmission via intracellular cascade","type":"narrow"}],"termid":"GO:1902532","terms_by_termid":{"GO:0031030":null,"GO:0032007":null,"GO:0035024":null,"GO:0046580":null,"GO:0106057":null,"GO:0140499":null,"GO:0180040":null,"GO:1902426":null,"GO:1903138":null,"GO:1903753":null,"GO:1903940":null,"GO:1904262":null,"GO:2000639":null}}


id: MONDO:0034189
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"cholangitis","termid":"MONDO:0004789"},{"relation_name":"is_a","term_name":"autoimmune hepatitis","termid":"MONDO:0016264"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0002515"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0004335","MONDO:0002515"],"is_obsolete":false,"name":"primary biliary cholangitis/primary sclerosing cholangitis and autoimmune hepatitis overlap syndrome","secondary_identifiers":["Orphanet:562639","GARD:22250","MEDGEN:1812237","UMLS:C5680117"],"termid":"MONDO:0034189","xrefs":{"Monarch":{"xref_id":"0034189"}}}


id: PBO:0108934
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PLEKHB2 pseudogene 1","termid":"PBO:0108934"}


id: GO:1900339
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of methane biosynthetic process from formic acid.","definition_xrefs":["GOC:TermGenie","GOC:mengo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of ketone metabolic process","termid":"GO:0010565"},{"relation_name":"is_a","term_name":"regulation of cellular respiration","termid":"GO:0043457"},{"relation_name":"is_a","term_name":"regulation of small molecule metabolic process","termid":"GO:0062012"},{"relation_name":"is_a","term_name":"regulation of alkane biosynthetic process","termid":"GO:1901577"},{"relation_name":"regulates","term_name":"methane biosynthetic process from formic acid","termid":"GO:2001127"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"regulates","termid":"GO:0006091"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006091","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"regulation of methane biosynthetic process from formic acid","termid":"GO:1900339"}


id: GO:1904918
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of L-histidine from the lysosomal lumen across the lysosomal membrane and into the cytosol.","definition_xrefs":["GOC:kmv","GO_REF:0000078","GOC:TermGenie","PMID:22822152"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amino acid transmembrane export from vacuole","termid":"GO:0032974"},{"relation_name":"is_a","term_name":"L-histidine transmembrane transport","termid":"GO:0089709"},{"relation_name":"is_a","term_name":"transmembrane transport from lysosomal lumen to cytosol","termid":"GO:0170063"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0008150","GO:0051179","GO:0055085"],"is_obsolete":false,"name":"L-histidine transmembrane transport from lysosomal lumen to cytosol","synonyms":[{"name":"transmembrane L-histidine transport from lysosomal lumen to cytosol","type":"exact"}],"termid":"GO:1904918"}


id: MONDO:0017566
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"macrodactyly of toes","termid":"MONDO:0017475"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"macrodactyly of toes, unilateral","secondary_identifiers":["Orphanet:295243","MEDGEN:1843435","GARD:21229","icd11.foundation:1009940304","UMLS:C5679988"],"synonyms":[{"name":"macrodactyly of foot, unilateral","type":"exact"}],"termid":"MONDO:0017566","xrefs":{"Monarch":{"xref_id":"0017566"}}}


id: GO:1990315
data:
  {"annotated_genes":["SJAG_03828","SJAG_02342","SJAG_06622","SJAG_06621","SJAG_00318","SJAG_04777","SJAG_03384","SJAG_03903","SJAG_00027","SJAG_02135","SJAG_02945"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[89349,102720,110761,110762,110763,110764,110765,110766,110767,112188,114335],"is_not":false,"summary":null,"term":"GO:1990315"}]},"cv_name":"cellular_component","definition":"A protein complex that consists of a phospho relay component and a MAPK cascade component. The complex is involved in signaling oxidative stress and osmostress.","definition_xrefs":["PMID:24255738"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex","termid":"GO:0032991"}],"gene_count":11,"genes_by_uniquename":{"SJAG_00027":null,"SJAG_00318":null,"SJAG_02135":null,"SJAG_02342":null,"SJAG_02945":null,"SJAG_03384":null,"SJAG_03828":null,"SJAG_03903":null,"SJAG_04777":null,"SJAG_06621":null,"SJAG_06622":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"Mcs4 RR-MAPKKK complex","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:1990315","terms_by_termid":{"GO:1990315":null}}


id: GO:0015133
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of uronic acid from one side of a membrane to the other. Uronic acids are any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monocarboxylic acid transmembrane transporter activity","termid":"GO:0008028"},{"relation_name":"is_a","term_name":"monosaccharide transmembrane transporter activity","termid":"GO:0015145"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0022857","GO:0005215","GO:0003674"],"is_obsolete":false,"name":"uronic acid transmembrane transporter activity","termid":"GO:0015133"}


id: SO:0100015
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"The more polar, carboxy-terminal region of the signal peptide (approx 3-7 aa).","definition_xrefs":["EBIBS:GAR"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cleaved_peptide_region","termid":"SO:0100011"},{"relation_name":"part_of","term_name":"signal_peptide","termid":"SO:0000418"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"SO:0000839"}],"interesting_parent_ids":["SO:0000839"],"is_obsolete":false,"name":"c_terminal_region","synonyms":[{"name":"C-region","type":"related"}],"termid":"SO:0100015"}


id: PBO:0087204
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"S-adenosylmethionine decarboxylase; required for the biosynthesis of spermidine and spermine; cells lacking Spe2p require spermine or spermidine for growth in the presence of oxygen but not when grown anaerobically","termid":"PBO:0087204"}


id: PBO:0073812
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SLC6A14 pseudogene 3","termid":"PBO:0073812"}


id: GO:1990621
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"An ESCRT complex that has AAA-ATPase activity and is involved in ESCRT-mediated intralumenal vesicle formation and the final stages of cytokinesis. The complex catalyzes disassembly of the ESCRT III filament around the neck of the budding vesicle in an ATP-driven reaction, resulting in membrane scission and recycling of the ESCRT III components back to the cytosol. In yeast, it is formed by the AAA ATPase Vps4 and its cofactor Vta1.","definition_xrefs":["PMID:21925211","GOC:ha","PMID:25164817","PMID:20696398","PMID:26775243","PMID:20653365","GOC:bhm","PMID:24456136"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ESCRT complex","termid":"GO:0036452"},{"relation_name":"is_a","term_name":"membrane protein complex","termid":"GO:0098796"},{"relation_name":"is_a","term_name":"ATPase complex","termid":"GO:1904949"},{"relation_name":"part_of","term_name":"endosome membrane","termid":"GO:0010008"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"part_of","termid":"GO:0005768"},{"rel_name":"part_of","termid":"GO:0031410"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005768","GO:0005575","GO:0031410","GO:0032991","GO:0005737"],"is_obsolete":false,"name":"ESCRT IV complex","synonyms":[{"name":"ESCRT-IV","type":"exact"},{"name":"VPS4A-VPS4B","type":"narrow"},{"name":"VPS4A/B complex","type":"narrow"},{"name":"Vps4 complex","type":"related"},{"name":"Vps4-Vta1 complex","type":"narrow"},{"name":"Vta1-Vps4 complex","type":"related"},{"name":"vacuolar protein sorting-associated complex","type":"related"}],"termid":"GO:1990621"}


id: PBO:0072801
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spalt like transcription factor 4 pseudogene 7","termid":"PBO:0072801"}


id: MONDO:0009209
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Autosomal recessive facio-digito-genital syndrome is a very rare syndrome including short stature, facial dysmorphism, hand abnormalities and shawl scrotum.","definition_xrefs":["Orphanet:1974"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive disease","termid":"MONDO:0006025"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome without intellectual disability","termid":"MONDO:0015161"},{"relation_name":"is_a","term_name":"faciodigitogenital syndrome","termid":"MONDO:0021005"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0006025"],"is_obsolete":false,"name":"autosomal recessive faciodigitogenital syndrome","secondary_identifiers":["UMLS:C1856871","MEDGEN:341637","GARD:5124","OMIM:227330"],"synonyms":[{"name":"Aarskog-like syndrome","type":"exact"},{"name":"Kuwait type faciodigitogenital syndrome","type":"related"},{"name":"Teebi-Naguib-Alawadi syndrome","type":"exact"},{"name":"facio-digito-genital syndrome, Kuwait type","type":"exact"},{"name":"faciodigitogenital syndrome, autosomal recessive","type":"related"}],"termid":"MONDO:0009209","xrefs":{"Monarch":{"xref_id":"0009209"}}}


id: PBO:0049944
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HIC ZBTB transcriptional repressor 2","termid":"PBO:0049944"}


id: PBO:0001239
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"from cerevisie","termid":"PBO:0001239"}


id: PBO:0059196
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MAS related GPR family member X3","termid":"PBO:0059196"}


id: GO:0000264
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Subunit of a heterotrimeric G-protein GTPase; associates tightly with the gamma subunit.","definition_xrefs":["GOC:mah","ISBN:0198547684"],"gene_count":0,"genotype_count":0,"name":"obsolete heterotrimeric G-protein GTPase, beta-subunit (obsolete GO:0000264)","synonyms":[{"name":"heterotrimeric G-protein GTPase, beta-subunit","type":"exact"}],"termid":"GO:0000264"}


id: PBO:0004447
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GRAM domain protein","termid":"PBO:0004447"}


id: PBO:0004361
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id: GO:1905591
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id: MONDO:0800147
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id: PBO:0069028
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id: GO:0009182
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id: PBO:0000155
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id: PBO:0065016
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id: PBO:0054615
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id: GO:0009269
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id: PBO:0076559
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id: GO:0031410
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id: MONDO:0100446
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id: GO:0042177
data:
  {"annotated_genes":["SJAG_00052","SJAG_01528","SJAG_00475","SJAG_03048","SJAG_02244"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[104183],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905785"},{"annotations":[79802,79281],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1904293"},{"annotations":[79064,108784],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0032435"}]},"cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process.","definition_xrefs":["PMID:24785082","GO_REF:0000058","GOC:kmv","GOC:obol","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of catabolic process","termid":"GO:0009895"},{"relation_name":"is_a","term_name":"regulation of protein catabolic process","termid":"GO:0042176"},{"relation_name":"is_a","term_name":"negative regulation of protein metabolic process","termid":"GO:0051248"},{"relation_name":"negatively_regulates","term_name":"protein catabolic process","termid":"GO:0030163"}],"gene_count":5,"genes_by_uniquename":{"SJAG_00052":null,"SJAG_00475":null,"SJAG_01528":null,"SJAG_02244":null,"SJAG_03048":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0030163"},{"rel_name":"regulates","termid":"GO:0030163"}],"interesting_parent_ids":["GO:0008150","GO:0030163"],"is_obsolete":false,"name":"negative regulation of protein catabolic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["GO:1903363","GO:2000599"],"synonyms":[{"name":"down regulation of cellular protein breakdown","type":"exact"},{"name":"down regulation of cellular protein catabolic process","type":"exact"},{"name":"down regulation of cellular protein catabolism","type":"exact"},{"name":"down regulation of cellular protein degradation","type":"exact"},{"name":"down regulation of protein catabolic process","type":"exact"},{"name":"down-regulation of cellular protein breakdown","type":"exact"},{"name":"down-regulation of cellular protein catabolic process","type":"exact"},{"name":"down-regulation of cellular protein catabolism","type":"exact"},{"name":"down-regulation of cellular protein degradation","type":"exact"},{"name":"down-regulation of protein catabolic process","type":"exact"},{"name":"downregulation of cellular protein breakdown","type":"exact"},{"name":"downregulation of cellular protein catabolic process","type":"exact"},{"name":"downregulation of cellular protein catabolism","type":"exact"},{"name":"downregulation of cellular protein degradation","type":"exact"},{"name":"downregulation of protein catabolic process","type":"exact"},{"name":"inhibition of cellular protein breakdown","type":"narrow"},{"name":"inhibition of cellular protein catabolic process","type":"narrow"},{"name":"inhibition of cellular protein catabolism","type":"narrow"},{"name":"inhibition of cellular protein degradation","type":"narrow"},{"name":"inhibition of protein catabolic process","type":"narrow"},{"name":"negative regulation of cellular protein breakdown","type":"exact"},{"name":"negative regulation of cellular protein catabolic process","type":"exact"},{"name":"negative regulation of cellular protein catabolism","type":"exact"},{"name":"negative regulation of cellular protein degradation","type":"exact"},{"name":"negative regulation of protein breakdown","type":"exact"},{"name":"negative regulation of protein catabolism","type":"exact"},{"name":"negative regulation of protein degradation","type":"exact"}],"termid":"GO:0042177","terms_by_termid":{"GO:0032435":null,"GO:1904293":null,"GO:1905785":null}}


id: PBO:0067154
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 204, pseudogene","termid":"PBO:0067154"}


id: GO:0046160
data:
  {"annotated_genes":["SJAG_04397","SJAG_03173"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[81786,80137],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006784"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving heme a, a derivative of heme found in cytochrome aa3.","definition_xrefs":["GOC:curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"heme metabolic process","termid":"GO:0042168"}],"gene_count":2,"genes_by_uniquename":{"SJAG_03173":null,"SJAG_04397":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0033013"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0033013"],"is_obsolete":false,"name":"heme a metabolic process","references_by_uniquename":{"GO_REF:0000033":null},"synonyms":[{"name":"haem a metabolic process","type":"exact"},{"name":"haem a metabolism","type":"exact"},{"name":"heme a metabolism","type":"exact"}],"termid":"GO:0046160","terms_by_termid":{"GO:0006784":null}}


id: PBO:0057774
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 2277","termid":"PBO:0057774"}


id: GO:0062001
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac endothelial to mesenchymal transition.","definition_xrefs":["PMID:26857067","GOC:rph","GOC:BHF","GOC:BHF_miRNA"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cell differentiation","termid":"GO:0045596"},{"relation_name":"is_a","term_name":"negative regulation of multicellular organismal process","termid":"GO:0051241"},{"relation_name":"is_a","term_name":"regulation of cardiac endothelial to mesenchymal transition","termid":"GO:0061999"},{"relation_name":"negatively_regulates","term_name":"cardiac endothelial to mesenchymal transition","termid":"GO:0140074"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of cardiac endothelial to mesenchymal transition","termid":"GO:0062001"}


id: GO:0044520
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of the activity of a vasoactive intestinal polypeptide receptor in the bitten organism.","definition_xrefs":["GOC:fj","GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete envenomation resulting in positive regulation of vasoactive intestinal polypeptide receptor activity in another organism (obsolete GO:0044520)","synonyms":[{"name":"envenomation resulting in positive regulation of VIP receptor activity in other organism","type":"exact"},{"name":"envenomation resulting in positive regulation of vasoactive intestinal polypeptide receptor activity in other organism","type":"exact"}],"termid":"GO:0044520"}


id: PBO:0046941
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 66 member C","termid":"PBO:0046941"}


id: PBO:0062696
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 51 subfamily B member 8 pseudogene","termid":"PBO:0062696"}


id: GO:0016172
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Inhibits the growth and recrystallization of ice crystals, thereby lowering the freezing point of water and preventing cellular damage at subzero temperatures. This activity is observed in various cold-adapted organisms, including certain fish, insects, and plants, and contributes to survival in extreme cold environments by stabilizing supercooled liquid states.","definition_xrefs":["PMID:33317024","GOC:cjm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ice binding","termid":"GO:0050825"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005488","GO:0003674"],"is_obsolete":false,"name":"antifreeze activity","termid":"GO:0016172"}


id: FYPO:0003573
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin at the silenced mating-type cassettes is decreased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased protein localization to heterochromatin during vegetative growth","termid":"FYPO:0002385"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0005447","FYPO:0000138","FYPO:0001320"],"is_obsolete":false,"name":"decreased protein localization to heterochromatin at silent mating-type cassette","synonyms":[{"name":"decreased protein localisation to heterochromatin at silent mating-type cassette","type":"exact"},{"name":"decreased protein localization to heterochromatin at mating-type region","type":"exact"},{"name":"decreased protein localization to heterochromatin at silent mating-type cassette during mitotic cell cycle","type":"related"},{"name":"decreased protein localization to heterochromatin at silent mating-type cassette during vegetative growth","type":"exact"},{"name":"decreased protein localization to mating-type region heterochromatin","type":"exact"},{"name":"decreased protein localization to silent mating type heterochromatin","type":"exact"},{"name":"reduced protein localization to heterochromatin at silent mating-type cassette","type":"exact"}],"termid":"FYPO:0003573"}


id: PBO:0036549
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HOPS/CORVET complex subunit, ubiquitin-protein ligase E3 Pep3/Vps18 (predicted)","termid":"PBO:0036549"}


id: FYPO:0002340
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of DNA recombination is decreased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal DNA recombination during vegetative growth","termid":"FYPO:0001345"},{"relation_name":"is_a","term_name":"decreased DNA recombination","termid":"FYPO:0002712"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000293"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0005447","FYPO:0000293","FYPO:0001320"],"is_obsolete":false,"name":"decreased DNA recombination during vegetative growth","synonyms":[{"name":"decreased DNA recombination during mitotic cell cycle","type":"related"},{"name":"decreased DNA recombination frequency during vegetative growth","type":"exact"},{"name":"decreased DNA recombination rate during vegetative growth","type":"related"},{"name":"decreased recombination during vegetative growth","type":"exact"},{"name":"reduced DNA recombination during vegetative growth","type":"exact"}],"termid":"FYPO:0002340"}


id: PBO:0049367
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GTF2I repeat domain containing 2","termid":"PBO:0049367"}


id: GO:0000123
data:
  {"annotated_genes":["SJAG_03792","SJAG_00783","SJAG_00641","SJAG_04205","SJAG_04613","SJAG_01009","SJAG_00087","SJAG_02165","SJAG_01711","SJAG_04274","SJAG_00584","SJAG_02990","SJAG_04793","SJAG_03579","SJAG_05282","SJAG_01658","SJAG_03599","SJAG_03036","SJAG_04815","SJAG_01385","SJAG_04355","SJAG_00676","SJAG_03628","SJAG_04097","SJAG_02385","SJAG_03145","SJAG_00349","SJAG_03230","SJAG_00187","SJAG_02927","SJAG_01475","SJAG_02066","SJAG_02773","SJAG_00545","SJAG_02541","SJAG_03776","SJAG_03752","SJAG_00184","SJAG_03668","SJAG_00411","SJAG_02458","SJAG_02629"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[90241],"is_not":false,"summary":null,"term":"GO:0000123"},{"annotations":[106252,92563,101489,107138],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0036410"},{"annotations":[95764,108347,109759,107139],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033100"},{"annotations":[79602],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990467"},{"annotations":[110903,105855,75536,74711,81894,81766,108709,75411,79171,80028,106543,94184,74664,69738,80817,100773,78031],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0035267"},{"annotations":[93221,63998,80622,75704,105185,75535,119428,75250,90306,67721,78454,72680,62732,73308,58160,78911,113602,118144,77313],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000124"},{"annotations":[58587,64000],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0046695"}]},"cv_name":"cellular_component","definition":"A protein complex that possesses histone acetyltransferase activity.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein acetyltransferase complex","termid":"GO:0031248"},{"relation_name":"part_of","term_name":"chromatin","termid":"GO:0000785"}],"gene_count":42,"genes_by_uniquename":{"SJAG_00087":null,"SJAG_00184":null,"SJAG_00187":null,"SJAG_00349":null,"SJAG_00411":null,"SJAG_00545":null,"SJAG_00584":null,"SJAG_00641":null,"SJAG_00676":null,"SJAG_00783":null,"SJAG_01009":null,"SJAG_01385":null,"SJAG_01475":null,"SJAG_01658":null,"SJAG_01711":null,"SJAG_02066":null,"SJAG_02165":null,"SJAG_02385":null,"SJAG_02458":null,"SJAG_02541":null,"SJAG_02629":null,"SJAG_02773":null,"SJAG_02927":null,"SJAG_02990":null,"SJAG_03036":null,"SJAG_03145":null,"SJAG_03230":null,"SJAG_03579":null,"SJAG_03599":null,"SJAG_03628":null,"SJAG_03668":null,"SJAG_03752":null,"SJAG_03776":null,"SJAG_03792":null,"SJAG_04097":null,"SJAG_04205":null,"SJAG_04274":null,"SJAG_04355":null,"SJAG_04613":null,"SJAG_04793":null,"SJAG_04815":null,"SJAG_05282":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005694"}],"interesting_parent_ids":["GO:0032991","GO:0005694","GO:0005575"],"is_obsolete":false,"name":"histone acetyltransferase complex","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000104":null,"GO_REF:0000107":null},"synonyms":[{"name":"histone acetylase complex","type":"exact"}],"termid":"GO:0000123","terms_by_termid":{"GO:0000123":null,"GO:0000124":null,"GO:0033100":null,"GO:0035267":null,"GO:0036410":null,"GO:0046695":null,"GO:1990467":null}}


id: GO:0080088
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of spermidine hydroxycinnamate conjugates.","definition_xrefs":["PMID:19077165"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amide biosynthetic process","termid":"GO:0043604"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"spermidine hydroxycinnamate conjugate biosynthetic process","termid":"GO:0080088"}


id: PBO:0050600
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hydroxy-delta-5-steroid dehydrogenase, 3 beta, pseudogene 5","termid":"PBO:0050600"}


id: PATO:0000406
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A curvature quality inhering in a bearer by virtue of the bearer's having or being marked by a curve or smoothly rounded bend.","definition_xrefs":["WordNet:WordNet"],"direct_ancestors":[{"relation_name":"is_a","term_name":"curvature","termid":"PATO:0001591"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"curved","synonyms":[{"name":"bowing","type":"narrow"},{"name":"curled","type":"related"}],"termid":"PATO:0000406"}


id: GO:0019673
data:
  {"annotated_genes":["SJAG_02783","SJAG_00890","SJAG_02648","SJAG_03188"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[79734,104911,77167,69856],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009298"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleotide-sugar metabolic process","termid":"GO:0009225"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00890":null,"SJAG_02648":null,"SJAG_02783":null,"SJAG_03188":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0044281","GO:0055086"],"is_obsolete":false,"name":"GDP-mannose metabolic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000041":null,"GO_REF:0000107":null},"synonyms":[{"name":"GDP-mannose metabolism","type":"exact"}],"termid":"GO:0019673","terms_by_termid":{"GO:0009298":null}}


id: GO:0110141
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which L-glutamate is transported from the cytosol into the mitochondrial matrix.","definition_xrefs":["GOC:vw","PMID:30297026"],"direct_ancestors":[{"relation_name":"is_a","term_name":"L-glutamate transmembrane transport","termid":"GO:0015813"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0051179","GO:0006810","GO:0055085","GO:0008150"],"is_obsolete":false,"name":"L-glutamate import into mitochondrion","termid":"GO:0110141"}


id: MONDO:0008965
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"CHARGE syndrome is a multiple congenital anomaly syndrome characterized by the variable combination of multiple anomalies, mainly Coloboma; Choanal atresia/stenosis; Cranial nerve dysfunction; Characteristic ear anomalies (known as the major 4 C's).","definition_xrefs":["Orphanet:138"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete syndrome or malformation associated with head and neck malformations (obsolete MONDO:0015501)","termid":"MONDO:0015501"},{"relation_name":"excluded_subClassOf","term_name":"obsolete lens shape anomaly (obsolete MONDO:0020237)","termid":"MONDO:0020237"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-variable intellectual disability syndrome","termid":"MONDO:0015160"},{"relation_name":"is_a","term_name":"congenital hypogonadotropic hypogonadism","termid":"MONDO:0015770"},{"relation_name":"is_a","term_name":"neurocristopathy","termid":"MONDO:0021635"},{"relation_name":"is_a","term_name":"cardiogenetic disease","termid":"MONDO:0100547"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"CHARGE syndrome","secondary_identifiers":["SCTID:47535005","MEDGEN:75567","UMLS:C0265354","NANDO:2200972","DOID:0050834","NANDO:1200464","ICD9:759.89","MESH:D058747","NORD:920","MedDRA:10064063","GARD:29","icd11.foundation:52086532","NCIT:C75100","OMIM:214800"],"synonyms":[{"name":"CHARGE association","type":"exact"},{"name":"CHARGE syndrome","type":"exact"},{"name":"Charge association--coloboma, heart anomaly, choanal atresia, retardation, genital and Ear anomalies","type":"related"},{"name":"Hall-Hittner syndrome","type":"exact"},{"name":"coloboma, heart anomaly, choanal atresia, retardation, genital and ear anomalies","type":"related"},{"name":"coloboma, heart defects, choanal atresia, retardation of Growth and development, genital abnormalities, and Ear anomalies association","type":"exact"},{"name":"coloboma, heart malformation, choanal atresia, retardation of Growth and development, genital abnormalities, and Ear malformations (CHARGE) association","type":"exact"},{"name":"coloboma-heart defects-atresia choanae-retardation of growth and development-genitourinary problems-ear abnormalities syndrome","type":"exact"}],"termid":"MONDO:0008965","xrefs":{"Monarch":{"xref_id":"0008965"}}}


id: GO:0045486
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2-oxoglutarate + a (2S)-flavan-4-one + O2 = a (2R,3R)-dihydroflavonol + CO2 + succinate.","definition_xrefs":["RHEA:18621"],"direct_ancestors":[{"relation_name":"is_a","term_name":"2-oxoglutarate-dependent dioxygenase activity","termid":"GO:0016706"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"flavanone 3-dioxygenase activity","secondary_identifiers":["MetaCyc:1.14.11.9-RXN","EC:1.14.11.9"],"synonyms":[{"name":"(2S)-flavanone 3-hydroxylase activity","type":"related"},{"name":"flavanone 3-beta-hydroxylase activity","type":"related"},{"name":"flavanone 3-hydroxylase activity","type":"related"},{"name":"flavanone 3beta-hydroxylase activity","type":"related"},{"name":"flavanone synthase I activity","type":"related"},{"name":"flavanone,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)","type":"related"},{"name":"naringenin 3-dioxygenase activity","type":"narrow"},{"name":"naringenin 3-hydroxylase activity","type":"related"},{"name":"naringenin,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity","type":"related"}],"termid":"GO:0045486"}


id: MONDO:0018445
data:
  {"annotated_genes":["SJAG_03689"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88050],"is_not":false,"summary":null,"term":"MONDO:0018445"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"overgrowth syndrome","termid":"MONDO:0019716"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03689":null},"genotype_count":0,"is_obsolete":false,"name":"global developmental delay - lung cysts - overgrowth - Wilms tumor syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1648360","Orphanet:404476","OMIM:618272","UMLS:C4748924","GARD:17676"],"synonyms":[{"name":"GLOW","type":"exact"},{"name":"GLOW syndrome, somatic mosaic","type":"exact"},{"name":"global developmental delay, lung cysts, overgrowth, and wilms tumor","type":"exact"},{"name":"global developmental delay, lung cysts, overgrowth, and wilms tumour","type":"exact"},{"name":"glow syndrome","type":"exact"}],"termid":"MONDO:0018445","terms_by_termid":{"MONDO:0018445":null},"xrefs":{"Monarch":{"xref_id":"0018445"}}}


id: MONDO:0011049
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A syndrome characterized by psychomotor delay, brachycephaly with flat face, small nose, microstomia, cleft palate, cataract, hearing loss, hypoplastic scrotum and digital anomalies.","definition_xrefs":["Orphanet:1272"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Fine-Lubinsky syndrome","secondary_identifiers":["OMIM:601353","SCTID:720955004","UMLS:C0795941","MESH:C537933","MEDGEN:163198","GARD:958"],"synonyms":[{"name":"brachycephaly, deafness, cataract and intellectual disability","type":"related"},{"name":"brachycephaly, deafness, cataract and mental retardation","type":"related"},{"name":"brachycephaly, deafness, cataract, microstomia, and intellectual disability","type":"related"},{"name":"brachycephaly, deafness, cataract, microstomia, and mental retardation","type":"related"},{"name":"brachycephaly-deafness-cataract-intellectual disability syndrome","type":"exact"},{"name":"fine-Lubinsky syndrome","type":"exact"}],"termid":"MONDO:0011049","xrefs":{"Monarch":{"xref_id":"0011049"}}}


id: PBO:0039876
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rho GTPase activating protein 32","termid":"PBO:0039876"}


id: GO:1990976
data:
  {"annotated_genes":["SJAG_03437","SJAG_00918","SJAG_05319","SJAG_01211","SJAG_01775","SJAG_02731","SJAG_01371","SJAG_05266","SJAG_05220","SJAG_01546","SJAG_01224"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[90957,91564,92794,98589,100440,102343,109343,110730,111740,115957,118780],"is_not":false,"summary":null,"term":"GO:1990976"}]},"cv_name":"biological_process","definition":"The directed movement of a protein along a microtubule to the mitotic spindle pole body, mediated by motor proteins.","definition_xrefs":["PMID:25987607"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein localization to mitotic spindle pole body","termid":"GO:1902440"},{"relation_name":"is_a","term_name":"protein transport along microtubule to spindle pole body","termid":"GO:1990852"}],"gene_count":11,"genes_by_uniquename":{"SJAG_00918":null,"SJAG_01211":null,"SJAG_01224":null,"SJAG_01371":null,"SJAG_01546":null,"SJAG_01775":null,"SJAG_02731":null,"SJAG_03437":null,"SJAG_05220":null,"SJAG_05266":null,"SJAG_05319":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0051179","GO:0008150"],"is_obsolete":false,"name":"protein transport along microtubule to mitotic spindle pole body","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:1990976","terms_by_termid":{"GO:1990976":null}}


id: PBO:0026793
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-septated_spheroid_vegetative_cell","termid":"PBO:0026793"}


id: GO:0052100
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process in which single-celled organisms of the same species monitor population density by detecting the concentration of small, diffusible signal molecules.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"gene_count":0,"genotype_count":0,"name":"obsolete intraspecies quorum sensing (obsolete GO:0052100)","termid":"GO:0052100"}


id: PBO:0053817
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1078","termid":"PBO:0053817"}


id: PBO:0072174
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S16 pseudogene 1","termid":"PBO:0072174"}


id: PBO:0053246
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"LHX1 divergent transcript","termid":"PBO:0053246"}


id: PBO:0046300
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"EMX2 opposite strand/antisense RNA","termid":"PBO:0046300"}


id: PBO:0042871
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CFAP100 divergent transcript","termid":"PBO:0042871"}


id: GO:0060788
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.","definition_xrefs":["GOC:tb","GOC:dph","GOC:sdb_2009"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure formation involved in morphogenesis","termid":"GO:0048646"},{"relation_name":"part_of","term_name":"ectodermal placode morphogenesis","termid":"GO:0071697"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"ectodermal placode formation","termid":"GO:0060788"}


id: MONDO:0020111
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete constitutional megaloblastic anemia due to folate metabolism disorder (obsolete MONDO:0020111)","secondary_identifiers":["Orphanet:98408"],"termid":"MONDO:0020111","xrefs":{"Monarch":{"xref_id":"0020111"}}}


id: GO:0050182
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: butanoyl-CoA + phosphate = butanoyl phosphate + CoA.","definition_xrefs":["RHEA:20892","EC:2.3.1.19"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acyltransferase activity, transferring groups other than amino-acyl groups","termid":"GO:0016747"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016746","GO:0003674","GO:0003824","GO:0016740"],"is_obsolete":false,"name":"phosphate butyryltransferase activity","secondary_identifiers":["KEGG_REACTION:R01174","MetaCyc:PHOSPHATE-BUTYRYLTRANSFERASE-RXN"],"synonyms":[{"name":"butanoyl-CoA:phosphate butanoyltransferase activity","type":"related"},{"name":"phosphotransbutyrylase activity","type":"related"}],"termid":"GO:0050182"}


id: PBO:0039356
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"amidohydrolase domain containing 2","termid":"PBO:0039356"}


id: PBO:0054748
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2157","termid":"PBO:0054748"}


id: MONDO:0100619
data:
  {"annotated_genes":["SJAG_01184","SJAG_02765","SJAG_00824","SJAG_04513"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87153],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0024556"},{"annotations":[88951],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014924"},{"annotations":[88950],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014925"},{"annotations":[87819],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013526"}]},"cv_name":"mondo","definition":"An epilepsy syndrome that has an onset during variable ages and stages of life.","direct_ancestors":[{"relation_name":"is_a","term_name":"epilepsy syndrome","termid":"MONDO:0015650"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00824":null,"SJAG_01184":null,"SJAG_02765":null,"SJAG_04513":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027"],"is_obsolete":false,"name":"variable age epilepsy syndrome","references_by_uniquename":{"PB_REF:0000006":null},"synonyms":[{"name":"variable age onset epilepsy","type":"broad"}],"termid":"MONDO:0100619","terms_by_termid":{"MONDO:0013526":null,"MONDO:0014924":null,"MONDO:0014925":null,"MONDO:0024556":null},"xrefs":{"Monarch":{"xref_id":"0100619"}}}


id: PBO:0065518
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"polypyrimidine tract binding protein 3","termid":"PBO:0065518"}


id: PBO:0045928
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"EF-hand domain containing 1","termid":"PBO:0045928"}


id: PBO:0055566
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 3002","termid":"PBO:0055566"}


id: PBO:0011123
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"guanyl-nucleotide exchange factor Syt22","termid":"PBO:0011123"}


id: PBO:0082581
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Chorismate mutase; catalyzes the conversion of chorismate to prephenate to initiate the tyrosine/phenylalanine-specific branch of aromatic amino acid biosynthesis","termid":"PBO:0082581"}


id: MONDO:0001516
data:
  {"annotated_genes":["SJAG_03815","SJAG_00754","SJAG_03328","SJAG_01537","SJAG_04321","SJAG_00053","SJAG_05289","SJAG_03170","SJAG_01260","SJAG_03894","SJAG_01522","SJAG_02399","SJAG_00853","SJAG_02695","SJAG_02919","SJAG_01352","SJAG_04907","SJAG_02286","SJAG_03598","SJAG_04567","SJAG_03495","SJAG_04084"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88509,88508],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008453"},{"annotations":[87632],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008026"},{"annotations":[87041],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011436"},{"annotations":[86925],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011585"},{"annotations":[86959],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010043"},{"annotations":[88829],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010532"},{"annotations":[87808,87807,87806],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008025"},{"annotations":[88422,88420,88421],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012080"},{"annotations":[88103,88102,88101],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013243"},{"annotations":[87104],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0015353"},{"annotations":[87957],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013884"},{"annotations":[87480],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0030860"},{"annotations":[87982],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011879"},{"annotations":[87005],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0060585"},{"annotations":[88098],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013853"},{"annotations":[88395],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010190"},{"annotations":[88884],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012890"},{"annotations":[88888],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012891"},{"annotations":[88703],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014485"},{"annotations":[87880],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014874"},{"annotations":[87975],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009669"},{"annotations":[88231],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009673"},{"annotations":[87837],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009672"},{"annotations":[87997],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010056"},{"annotations":[88064],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010338"}]},"cv_name":"mondo","definition":"A motor neuron disease that affect the muscles, and characterized by muscle weakness and atrophy resulting from progressive degeneration and irreversible loss of the anterior horn cells in the spinal cord (i.e., lower motor neurons) and the brain stem nuclei. The severity of the condition; the associated signs and symptoms; and the age at which symptoms develop varies by subtype. In general, people with spinal muscular atrophy (SMA) experience progressive weakness and atrophy of muscles involved in mobility, the ability to sit unassisted, and head control. Breathing and swallowing may also be affected in severe cases. SMA is generally caused by changes (mutations) in the SMN1 gene and is inherited in an autosomal recessive manner. Extra copies of the SMN2 gene modify the severity of SMA. Rare autosomal dominant (caused by mutations in DYNC1H1, BICD2, or VAPB genes) and X-linked (caused by mutations in UBA1) forms of SMA exist. Treatment is based on the signs and symptoms present in each person.","definition_xrefs":["GARD:7674","PMID:20301526"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"myopathy","termid":"MONDO:0005336"},{"relation_name":"is_a","term_name":"anterior horn disorder","termid":"MONDO:0003182"},{"relation_name":"is_a","term_name":"hereditary motor neuron disease","termid":"MONDO:0024257"}],"gene_count":22,"genes_by_uniquename":{"SJAG_00053":null,"SJAG_00754":null,"SJAG_00853":null,"SJAG_01260":null,"SJAG_01352":null,"SJAG_01522":null,"SJAG_01537":null,"SJAG_02286":null,"SJAG_02399":null,"SJAG_02695":null,"SJAG_02919":null,"SJAG_03170":null,"SJAG_03328":null,"SJAG_03495":null,"SJAG_03598":null,"SJAG_03815":null,"SJAG_03894":null,"SJAG_04084":null,"SJAG_04321":null,"SJAG_04567":null,"SJAG_04907":null,"SJAG_05289":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"spinal muscular atrophy","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["NANDO:2100231","NCIT:C85075","DOID:12377","UMLS:C0026847","EFO:0008525","MESH:D009134","icd11.foundation:71074342","ICD9:335.10","MEDGEN:7755","NANDO:2200853","SCTID:5262007","ICD9:335.19","NANDO:1200003","ICD9:335.1"],"termid":"MONDO:0001516","terms_by_termid":{"MONDO:0008025":null,"MONDO:0008026":null,"MONDO:0008453":null,"MONDO:0009669":null,"MONDO:0009672":null,"MONDO:0009673":null,"MONDO:0010043":null,"MONDO:0010056":null,"MONDO:0010190":null,"MONDO:0010338":null,"MONDO:0010532":null,"MONDO:0011436":null,"MONDO:0011585":null,"MONDO:0011879":null,"MONDO:0012080":null,"MONDO:0012890":null,"MONDO:0012891":null,"MONDO:0013243":null,"MONDO:0013853":null,"MONDO:0013884":null,"MONDO:0014485":null,"MONDO:0014874":null,"MONDO:0015353":null,"MONDO:0030860":null,"MONDO:0060585":null},"xrefs":{"Monarch":{"xref_id":"0001516"}}}


id: GO:0030641
data:
  {"annotated_genes":["SJAG_00301","SJAG_03962","SJAG_01129","SJAG_02470","SJAG_04258","SJAG_05294","SJAG_01397","SJAG_01817","SJAG_00212","SJAG_04616","SJAG_00516","SJAG_00136","SJAG_00605","SJAG_04955","SJAG_01913","SJAG_01669","SJAG_02023","SJAG_02716"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[102332],"is_not":false,"summary":null,"term":"GO:0030641"},{"annotations":[74954,67956,79665,72540,73140],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051453"},{"annotations":[80261,74784,74521,105731,75822,81796,101836,97647,97467,89851,72635,103458],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0007035"}]},"cv_name":"biological_process","definition":"Any process involved in the maintenance of an internal equilibrium of hydrogen ions (protons) within a cell or between a cell and its external environment.","definition_xrefs":["GOC:tb","GOC:mah","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of pH","termid":"GO:0006885"},{"relation_name":"is_a","term_name":"intracellular monoatomic cation homeostasis","termid":"GO:0030003"}],"gene_count":18,"genes_by_uniquename":{"SJAG_00136":null,"SJAG_00212":null,"SJAG_00301":null,"SJAG_00516":null,"SJAG_00605":null,"SJAG_01129":null,"SJAG_01397":null,"SJAG_01669":null,"SJAG_01817":null,"SJAG_01913":null,"SJAG_02023":null,"SJAG_02470":null,"SJAG_02716":null,"SJAG_03962":null,"SJAG_04258":null,"SJAG_04616":null,"SJAG_04955":null,"SJAG_05294":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of cellular pH","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null,"GO_REF:0000117":null},"synonyms":[{"name":"cellular hydrogen ion homeostasis","type":"exact"},{"name":"proton homeostasis","type":"exact"}],"termid":"GO:0030641","terms_by_termid":{"GO:0007035":null,"GO:0030641":null,"GO:0051453":null}}


id: PBO:0050289
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HNF1 homeobox B","termid":"PBO:0050289"}


id: PBO:0032771
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"translation initiation factor eIF2B alpha subunit","termid":"PBO:0032771"}


id: PBO:0030476
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_vacuolar_cysteine_level","termid":"PBO:0030476"}


id: PBO:0065620
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein tyrosine phosphatase mitochondrial 1","termid":"PBO:0065620"}


id: GO:0043595
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A layer surrounding a bacterial endospore found inside the outer endospore membrane, but outside the membrane surrounding the endospore core. It consists of peptidoglycan of a different chemical nature than that found in vegetative cell walls which results in less cross-linking of peptidoglycan.","definition_xrefs":["GOC:mlg"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"endospore external encapsulating structure","termid":"GO:0043591"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005618"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005618","GO:0005575"],"is_obsolete":false,"name":"endospore cortex","termid":"GO:0043595"}


id: PBO:0083669
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Endoplasmic reticulum protein; member of DUP380 subfamily of conserved, often subtelomerically-encoded proteins; may contribute to maintenance of ER and nuclear morphology; null mutants have distorted nuclear envelope shape, and discontinuous, misshapen perinuclear ER","termid":"PBO:0083669"}


id: MONDO:0001884
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A neoplasm involving a abducens nerve.","definition_xrefs":["MONDO:patterns/neoplasm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cranial nerve neoplasm","termid":"MONDO:0002633"},{"relation_name":"is_a","term_name":"abducens nerve disorder","termid":"MONDO:0020594"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"abducens nerve neoplasm","secondary_identifiers":["ICD9:239.7","NCIT:C5826","MEDGEN:224732","UMLS:C1263898","SCTID:126972009","DOID:14125"],"synonyms":[{"name":"VIth cranial nerve neoplasms","type":"exact"},{"name":"VIth cranial nerve tumors","type":"exact"},{"name":"VIth cranial nerve tumours","type":"exact"},{"name":"abducens nerve neoplasm (disease)","type":"exact"},{"name":"abducens nerve neoplasms","type":"exact"},{"name":"abducens nerve tumor","type":"exact"},{"name":"abducens nerve tumors","type":"exact"},{"name":"abducens nerve tumour","type":"exact"},{"name":"abducens nerve tumours","type":"exact"},{"name":"neoplasm of abducens nerve","type":"exact"},{"name":"neoplasm of sixth cranial nerve","type":"exact"},{"name":"neoplasm of the abducens nerve","type":"exact"},{"name":"neoplasm of the sixth cranial nerve","type":"exact"},{"name":"sixth cranial nerve neoplasm","type":"exact"},{"name":"sixth cranial nerve neoplasms","type":"exact"},{"name":"sixth cranial nerve tumor","type":"exact"},{"name":"sixth cranial nerve tumors","type":"exact"},{"name":"sixth cranial nerve tumour","type":"exact"},{"name":"sixth cranial nerve tumours","type":"exact"},{"name":"tumor of abducens nerve","type":"exact"},{"name":"tumor of sixth cranial nerve","type":"exact"},{"name":"tumor of the abducens nerve","type":"exact"},{"name":"tumor of the sixth cranial nerve","type":"exact"},{"name":"tumour of abducens nerve","type":"exact"},{"name":"tumour of sixth cranial nerve","type":"exact"},{"name":"tumour of the abducens nerve","type":"exact"},{"name":"tumour of the sixth cranial nerve","type":"exact"}],"termid":"MONDO:0001884","xrefs":{"Monarch":{"xref_id":"0001884"}}}


id: PBO:0063713
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphoglucomutase 5 pseudogene 2","termid":"PBO:0063713"}


id: PBO:0081093
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger DHHC-type containing 20 pseudogene 2","termid":"PBO:0081093"}


id: PBO:0070124
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U7 small nuclear 38 pseudogene","termid":"PBO:0070124"}


id: PBO:0077583
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tropomodulin 2","termid":"PBO:0077583"}


id: GO:0018135
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete peptidyl-cysteine cyclase activity (obsolete GO:0018135)","synonyms":[{"name":"peptidyl-cysteine cyclase activity","type":"exact"}],"termid":"GO:0018135"}


id: GO:0072045
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"convergent extension involved in organogenesis","termid":"GO:0060029"},{"relation_name":"part_of","term_name":"nephron morphogenesis","termid":"GO:0072028"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"convergent extension involved in nephron morphogenesis","termid":"GO:0072045"}


id: PBO:0082891
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant","termid":"PBO:0082891"}


id: MONDO:0012527
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any early-onset non-syndromic cataract in which the cause of the disease is a mutation in the PITX3 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"early-onset non-syndromic cataract","termid":"MONDO:0011060"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"cataract 11 multiple types","secondary_identifiers":["MESH:C535344","UMLS:C1864567","MEDGEN:351162","OMIM:610623","DOID:0110249"],"synonyms":[{"name":"CPP4","type":"narrow"},{"name":"CTPP4","type":"narrow"},{"name":"CTRCT11","type":"exact"},{"name":"Cpp4","type":"related"},{"name":"PITX3 early-onset non-syndromic cataract","type":"exact"},{"name":"Posterior polar cataract, 4","type":"related"},{"name":"cataract 11 with microphthalmia and neurodevelopmental abnormalities","type":"related"},{"name":"cataract 11, multiple types","type":"related"},{"name":"cataract 11, syndromic, autosomal recessive","type":"exact"},{"name":"cataract, posterior polar, 4","type":"related"},{"name":"early-onset non-syndromic cataract caused by mutation in PITX3","type":"exact"},{"name":"posterior polar cataract 4","type":"narrow"}],"termid":"MONDO:0012527","xrefs":{"Monarch":{"xref_id":"0012527"}}}


id: FYPO:0003151
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to heat is lower than normal. Total protein or a specific protein may be affected.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased protein level during vegetative growth","termid":"FYPO:0001324"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0006551"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0005447","FYPO:0001985","FYPO:0006551","FYPO:0000002"],"is_obsolete":false,"name":"decreased protein level during cellular response to heat","synonyms":[{"name":"decreased protein accumulation during cellular response to heat","type":"related"},{"name":"decreased protein level during cellular response to heat during mitotic cell cycle","type":"related"},{"name":"decreased protein level during cellular response to heat during vegetative growth","type":"exact"},{"name":"reduced protein level during cellular response to heat","type":"exact"},{"name":"thermo-sensitive","type":"related"},{"name":"thermosensitive","type":"related"}],"termid":"FYPO:0003151"}


id: GO:0031695
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to an alpha-2B adrenergic receptor.","definition_xrefs":["GOC:mah","GOC:nln"],"direct_ancestors":[{"relation_name":"is_a","term_name":"adrenergic receptor binding","termid":"GO:0031690"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005515","GO:0005488"],"is_obsolete":false,"name":"alpha-2B adrenergic receptor binding","synonyms":[{"name":"alpha-2B adrenergic receptor ligand","type":"narrow"}],"termid":"GO:0031695"}


id: GO:0036337
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals initiated by the binding of a ligand to a Fas receptor on the surface of the cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Fas is a death domain-containing member of the tumor necrosis factor receptor (TNFR) superfamily.","definition_xrefs":["Wikipedia:Fas_receptor","PMID:12040174","GOC:nhn"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell surface receptor signaling pathway","termid":"GO:0007166"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"Fas signaling pathway","synonyms":[{"name":"Apo-1 signaling pathway","type":"exact"},{"name":"CD95 signaling pathway","type":"exact"},{"name":"FAS ligand-Fas signaling pathway","type":"narrow"},{"name":"Fas receptor signaling pathway","type":"exact"},{"name":"Fas-FasL signaling pathway","type":"narrow"},{"name":"FasL signaling pathway","type":"related"},{"name":"FasR signaling pathway","type":"exact"}],"termid":"GO:0036337"}


id: PBO:0070665
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L7 pseudogene 36","termid":"PBO:0070665"}


id: GO:0044873
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a lipoprotein is transported to, or maintained in, a specific location in a membrane.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lipoprotein localization","termid":"GO:0044872"},{"relation_name":"is_a","term_name":"localization within membrane","termid":"GO:0051668"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0008150","GO:0051179"],"is_obsolete":false,"name":"lipoprotein localization to membrane","termid":"GO:0044873"}


id: PBO:0052965
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"L1CAM antisense RNA 1","termid":"PBO:0052965"}


id: MOD:00047
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.","definition_xrefs":["PubMed:7678926","OMSSA:7","PubMed:12923550","DeltaMass:0","RESID:AA0038","Unimod:21#T","ChEBI:21967"],"direct_ancestors":[{"relation_name":"is_a","term_name":"residues isobaric at 181.00-181.02 Da","termid":"MOD:00773"},{"relation_name":"is_a","term_name":"modified L-threonine residue","termid":"MOD:00917"},{"relation_name":"is_a","term_name":"O-phosphorylated residue","termid":"MOD:01455"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00696"}],"interesting_parent_ids":["MOD:00696"],"is_obsolete":false,"name":"O-phospho-L-threonine","synonyms":[{"name":"(2S,3R)-2-amino-3-(phosphonooxy)butanoic acid","type":"exact"},{"name":"2-amino-3-hydroxybutanoic acid 3-phosphate","type":"exact"},{"name":"2-azanyl-3-(phosphonooxy)butanoic acid","type":"exact"},{"name":"MOD_RES Phosphothreonine","type":"exact"},{"name":"O-phospho-L-threonine","type":"exact"},{"name":"O-phosphorylated L-threonine","type":"exact"},{"name":"O3-phosphothreonine","type":"exact"},{"name":"OPThr","type":"exact"},{"name":"Phospho","type":"related"},{"name":"Phospho Threonyl","type":"exact"},{"name":"Phosphorylation","type":"related"},{"name":"phosphorylationt","type":"exact"},{"name":"threonine phosphate ester","type":"exact"}],"termid":"MOD:00047"}


id: MONDO:0001600
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign cyst located in the salivary gland that is lined by epithelium and filled with mucoid fluid, tissue, or other material; it is usually caused by duct obstruction.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"salivary gland disorder","termid":"MONDO:0001142"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mucocele of salivary gland","secondary_identifiers":["icd11.foundation:48444833","MESH:D011900","UMLS:C0026686","DOID:12904","MEDGEN:10117","ICD10CM:K11.6","SCTID:69825009","ICD9:527.6"],"synonyms":[{"name":"mucous retention cyst of salivary gland","type":"exact"},{"name":"ranula","type":"exact"},{"name":"salivary cyst","type":"exact"},{"name":"salivary gland mucocele","type":"exact"}],"termid":"MONDO:0001600","xrefs":{"Monarch":{"xref_id":"0001600"}}}


id: PBO:0005577
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"60S ribosomal protein L39","termid":"PBO:0005577"}


id: PBO:0091754
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"II:g.1987118delG","termid":"PBO:0091754"}


id: GO:0032664
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of interleukin-20 production.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cytokine production","termid":"GO:0001817"},{"relation_name":"regulates","term_name":"interleukin-20 production","termid":"GO:0032624"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"regulation of interleukin-20 production","secondary_identifiers":["GO:0045387"],"synonyms":[{"name":"regulation of IL-20 production","type":"exact"},{"name":"regulation of interleukin-20 biosynthetic process","type":"narrow"}],"termid":"GO:0032664"}


id: MONDO:0018883
data:
  {"annotated_genes":["SJAG_01957","SJAG_01537"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87382],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012071"},{"annotations":[86876],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010020"}]},"cv_name":"mondo","definition":"A lipodystrophy characterized by the association of lipoatrophy, hypertriglyceridemia, hepatomegaly and acromegaloid features. BSCL belongs to the group of extreme insulin resistance syndromes, which also includes leprechaunism, Rabson-Mendenhall syndrome, acquired generalized lipodystrophy, and types A and B insulin resistance.","definition_xrefs":["Orphanet:528"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"diabetes mellitus","termid":"MONDO:0005015"},{"relation_name":"excluded_subClassOf","term_name":"progeroid syndrome","termid":"MONDO:0015333"},{"relation_name":"is_a","term_name":"hereditary lipodystrophy","termid":"MONDO:0020087"},{"relation_name":"is_a","term_name":"disorder of development or morphogenesis","termid":"MONDO:0021147"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01537":null,"SJAG_01957":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005093","MONDO:0005066"],"is_obsolete":false,"name":"Berardinelli-Seip congenital lipodystrophy","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["NANDO:1200859","NANDO:2200465","MedDRA:10024603","NCIT:C84594","ICD9:250.80","icd11.foundation:1628738474","GARD:13388","SCTID:127012008","icd11.foundation:641763399"],"synonyms":[{"name":"BSCL","type":"exact"},{"name":"Beradinelli-Seip syndrome","type":"exact"},{"name":"Berardinelli Seip syndrome","type":"exact"},{"name":"Berardinelli lipodystrophy syndrome","type":"exact"},{"name":"Brunzell syndrome","type":"exact"},{"name":"GCL","type":"exact"},{"name":"Lawrence-Seip syndrome","type":"related"},{"name":"Seip-Bernardinelli syndrome","type":"exact"},{"name":"congenital generalised lipodystrophy","type":"related"},{"name":"congenital generalized lipodystrophy","type":"related"},{"name":"generalised congenital lipodystrophy","type":"exact"},{"name":"generalized congenital lipodystrophy","type":"exact"},{"name":"lipoatrophic diabetes","type":"related"},{"name":"total lipodystrophy","type":"exact"}],"termid":"MONDO:0018883","terms_by_termid":{"MONDO:0010020":null,"MONDO:0012071":null},"xrefs":{"Monarch":{"xref_id":"0018883"}}}


id: FYPO:0006503
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the localization of a protein to the actin fusion focus is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein transport","termid":"FYPO:0005744"},{"relation_name":"is_a","term_name":"abnormal protein localization during mating","termid":"FYPO:0005989"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0000002","FYPO:0001985","FYPO:0005447"],"is_obsolete":false,"name":"abnormal protein localization to actin fusion focus","synonyms":[{"name":"abnormal protein localisation to actin fusion focus","type":"exact"}],"termid":"FYPO:0006503"}


id: PBO:0061688
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nucleoporin 160","termid":"PBO:0061688"}


id: PBO:0078155
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T cell receptor alpha variable 33 (pseudogene)","termid":"PBO:0078155"}


id: PBO:0087967
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Transporter of thiamine or related compound; contributes to uptake of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (acadesine); shares sequence similarity with Thi7p","termid":"PBO:0087967"}


id: GO:0043290
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid.","definition_xrefs":["PMID:34956282","GOC:jl","PMID:33721905"],"direct_ancestors":[{"relation_name":"is_a","term_name":"isoprenoid catabolic process","termid":"GO:0008300"},{"relation_name":"is_a","term_name":"apocarotenoid metabolic process","termid":"GO:0043288"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0006629"],"is_obsolete":false,"name":"apocarotenoid catabolic process","synonyms":[{"name":"apo carotenoid catabolic process","type":"exact"},{"name":"apocarotenoid breakdown","type":"exact"},{"name":"apocarotenoid catabolism","type":"exact"},{"name":"apocarotenoid degradation","type":"exact"}],"termid":"GO:0043290"}


id: PBO:0013033
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"human HID1 ortholog 1","termid":"PBO:0013033"}


id: GO:0051263
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The modification of serine to N-[5-(6-O-seryl-beta-glucosyl)-2,3-dihydroxybenzoyl]-O-[N-(2,3-dihydroxybenzoyl)-O-[N-(2,3-dihydroxybenzoyl)seryl]seryl]serine as found in microcin E492 produced from the mceA gene in plasmid pJAM229 of the E. coli VCS257 strain and the K. pneumoniae RYC492 strain.","definition_xrefs":["RESID:AA0374"],"gene_count":0,"genotype_count":0,"name":"obsolete microcin E492 biosynthetic process by siderophore ester modification of peptidyl-serine (obsolete GO:0051263)","synonyms":[{"name":"microcin E492 anabolism by siderophore ester modification of peptidyl-serine","type":"exact"},{"name":"microcin E492 formation by siderophore ester modification of peptidyl-serine","type":"exact"},{"name":"microcin E492 synthesis by siderophore ester modification of peptidyl-serine","type":"exact"}],"termid":"GO:0051263"}


id: GO:1904363
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of calcitonin secretion.","definition_xrefs":["GO_REF:0000058","PMID:11278900","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of peptide hormone secretion","termid":"GO:0090278"},{"relation_name":"is_a","term_name":"regulation of calcitonin secretion","termid":"GO:1904362"},{"relation_name":"negatively_regulates","term_name":"calcitonin secretion","termid":"GO:0036161"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0006810"},{"rel_name":"negatively_regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"negative regulation of calcitonin secretion","synonyms":[{"name":"down regulation of calcitonin secretion","type":"exact"},{"name":"down-regulation of calcitonin secretion","type":"exact"},{"name":"downregulation of calcitonin secretion","type":"exact"},{"name":"inhibition of calcitonin secretion","type":"narrow"}],"termid":"GO:1904363"}


id: PBO:0074327
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SMARCA2 antisense RNA 1","termid":"PBO:0074327"}


id: PBO:0081010
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger and BTB domain containing 45 pseudogene 1","termid":"PBO:0081010"}


id: FYPO:0004741
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount of filamentous actin (F-actin) in the actomyosin contractile ring is normal (i.e. indistinguishable from wild type) during mitotic anaphase B.","definition_xrefs":["PMID:25688133","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal actomyosin contractile ring","termid":"FYPO:0004740"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000257","FYPO:0001320"],"is_obsolete":false,"name":"normal F-actin level in actomyosin contractile ring during anaphase B","synonyms":[{"name":"normal F-actin level in actomyosin contractile ring during anaphase B during mitotic cell cycle","type":"related"},{"name":"normal F-actin level in actomyosin contractile ring during anaphase B during vegetative growth","type":"exact"},{"name":"normal F-actin level in contractile ring during anaphase B","type":"exact"},{"name":"normal F-actin level in cytokinetic contractile ring during anaphase B","type":"exact"},{"name":"normal abundance of actin in actomyosin contractile ring in anaphase B","type":"exact"},{"name":"normal actomyosin contractile ring F-actin level during anaphase B","type":"exact"},{"name":"normal filamentous actin level in actomyosin contractile ring during anaphase B","type":"exact"}],"termid":"FYPO:0004741"}


id: MONDO:0006258
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A non-neoplastic hamartomatous polyp that arises from the stomach and intestinal tract. It is characterized by the presence of tortuous and cystically dilated glands, edematous changes, and inflammation.","definition_xrefs":["NCIT:C3826"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gastrointestinal hamartoma","termid":"MONDO:0006231"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"juvenile polyp","secondary_identifiers":["MEDGEN:113158","EFO:1000310","UMLS:C0221273"],"synonyms":[{"name":"juvenile polyp","type":"exact"},{"name":"retention polyp","type":"exact"}],"termid":"MONDO:0006258","xrefs":{"Monarch":{"xref_id":"0006258"}}}


id: MONDO:0015146
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"lissencephaly spectrum disorders","termid":"MONDO:0018838"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320"],"is_obsolete":false,"name":"classic lissencephaly","secondary_identifiers":["Orphanet:102009","GARD:5049","UMLS:C0431375","MEDGEN:98463","icd11.foundation:570001324","NANDO:1201068","NANDO:1201069"],"synonyms":[{"name":"ILS","type":"related"},{"name":"lissencephaly classic","type":"related"},{"name":"lissencephaly sequence isolated","type":"related"},{"name":"lissencephaly type 1","type":"exact"}],"termid":"MONDO:0015146","xrefs":{"Monarch":{"xref_id":"0015146"}}}


id: PBO:0077321
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein 59 like","termid":"PBO:0077321"}


id: MONDO:0019332
data:
  {"annotated_genes":["SJAG_05011"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86797],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007858"}]},"cv_name":"mondo","definition":"Punctate palmoplantar keratoderma type I (PPKP1), also known as Buschke-Fischer-Brauer syndrome, is a very rare hereditary skin disease characterized by irregularly distributed epidermal hyperkeratosis of the palms and soles with wide variation among patients..","definition_xrefs":["Orphanet:79501"],"direct_ancestors":[{"relation_name":"is_a","term_name":"punctate palmoplantar keratoderma","termid":"MONDO:0017675"}],"gene_count":1,"genes_by_uniquename":{"SJAG_05011":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"punctate palmoplantar keratoderma type 1","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:372099","GARD:3103","SCTID:717184007","UMLS:C1835662"],"synonyms":[{"name":"Brauer-Buschke-Fischer syndrome","type":"related"},{"name":"Buschke-Fischer-Brauer syndrome","type":"exact"},{"name":"PPKP1","type":"exact"},{"name":"keratoderma, palmoplantar punctate type 1","type":"related"},{"name":"keratodermia palmoplantaris papulosa, Buschke-Fischer-Brauer type","type":"exact"},{"name":"punctate palmoplantar keratoderma type I","type":"related"},{"name":"type I punctate palmoplantar keratoderma","type":"related"}],"termid":"MONDO:0019332","terms_by_termid":{"MONDO:0007858":null},"xrefs":{"Monarch":{"xref_id":"0019332"}}}


id: PBO:0050446
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heterogeneous nuclear ribonucleoprotein U","termid":"PBO:0050446"}


id: GO:0015214
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a pyrimidine nucleoside, a pyrimidine base covalently bonded to a ribose or deoxyribose sugar from one side of a membrane to the other.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleoside transmembrane transporter activity","termid":"GO:0005337"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0022857","GO:0003674","GO:0005215"],"is_obsolete":false,"name":"pyrimidine nucleoside transmembrane transporter activity","termid":"GO:0015214"}


id: PBO:0081678
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 599","termid":"PBO:0081678"}


id: PBO:0075088
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, C/D box 138","termid":"PBO:0075088"}


id: MONDO:0006244
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A biologic subset of breast carcinoma defined by high expression of HER2, GRB7, and TRAP100, and by lack of expression of estrogen receptor (ER).","definition_xrefs":["NCIT:C53556"],"direct_ancestors":[{"relation_name":"is_a","term_name":"breast carcinoma by gene expression profile","termid":"MONDO:0006116"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"HER2 positive breast carcinoma","secondary_identifiers":["EFO:1000294","DOID:0060079","UMLS:C1960398","MEDGEN:743175","SCTID:427685000"],"synonyms":[{"name":"ERBB2 Overexpressing subtype of breast carcinoma","type":"exact"},{"name":"HER2 Overexpressing breast carcinoma","type":"exact"},{"name":"HER2 Overexpressing subtype of breast carcinoma","type":"exact"},{"name":"HER2 Positive breast cancer","type":"exact"},{"name":"HER2 positive breast carcinoma","type":"exact"},{"name":"Her2-receptor positive breast cancer","type":"exact"}],"termid":"MONDO:0006244","xrefs":{"Monarch":{"xref_id":"0006244"}}}


id: PBO:0051683
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"inhibitor of carbonic anhydrase pseudogene","termid":"PBO:0051683"}


id: GO:0004151
data:
  {"annotated_genes":["SJAG_00444"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[73341],"is_not":false,"summary":null,"term":"GO:0004151"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: (S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate + H+.","definition_xrefs":["EC:3.5.2.3","RHEA:24296"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides","termid":"GO:0016812"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00444":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016810"},{"rel_name":"is_a","termid":"GO:0016787"}],"interesting_parent_ids":["GO:0016787","GO:0003674","GO:0003824","GO:0016810"],"is_obsolete":false,"name":"dihydroorotase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["KEGG_REACTION:R01993","Reactome:R-HSA-73571","MetaCyc:DIHYDROOROT-RXN"],"synonyms":[{"name":"(S)-dihydroorotate amidohydrolase activity","type":"related"},{"name":"DHOase activity","type":"related"},{"name":"carbamoylaspartic dehydrase activity","type":"related"},{"name":"dihydroorotate hydrolase activity","type":"related"}],"termid":"GO:0004151","terms_by_termid":{"GO:0004151":null}}


id: PBO:0113553
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"oligosaccharyltransferase complex, dolichyl-diphosphooligosaccharide-protein glycotransferase catalytic subunit, Stt3","termid":"PBO:0113553"}


id: GO:0061981
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: L-3-hydroxykynurenine + H2O = 3-hydroxyanthranilate + L-alanine.","definition_xrefs":["PMID:17300176"],"gene_count":0,"genotype_count":0,"name":"obsolete 3-hydroxykynureninase activity (obsolete GO:0061981)","termid":"GO:0061981"}


id: MONDO:0958202
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Moyamoya disease","termid":"MONDO:0016820"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"moyamoya disease 7","secondary_identifiers":["MEDGEN:1851566","OMIM:620687","UMLS:C5882748"],"termid":"MONDO:0958202","xrefs":{"Monarch":{"xref_id":"0958202"}}}


id: PBO:0080597
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WD repeat domain 27","termid":"PBO:0080597"}


id: PBO:0053929
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1228","termid":"PBO:0053929"}


id: MONDO:0044992
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A disease or disorder that involves the mouth mucosa.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mouth disorder","termid":"MONDO:0006858"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mouth mucosa disorder","secondary_identifiers":["UMLS:C1290071","SCTID:128046007","MEDGEN:712457"],"synonyms":[{"name":"disease of mouth mucosa","type":"exact"},{"name":"disease or disorder of mouth mucosa","type":"exact"},{"name":"disorder of mouth mucosa","type":"exact"},{"name":"disorder of oral mucous membrane","type":"exact"},{"name":"mouth mucosa disease or disorder","type":"exact"},{"name":"oral mucous membrane disease","type":"exact"}],"termid":"MONDO:0044992","xrefs":{"Monarch":{"xref_id":"0044992"}}}


id: GO:0010045
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nickel cation stimulus.","definition_xrefs":["GOC:sm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to metal ion","termid":"GO:0010038"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to nickel cation","synonyms":[{"name":"response to nickel","type":"exact"}],"termid":"GO:0010045"}


id: PBO:0003336
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"inositol-polyphosphate 5-phosphatase, synaptojanin homolog 2 (predicted)","termid":"PBO:0003336"}


id: SO:0000013
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A small non coding RNA sequence, present in the cytoplasm.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"derives_from","term_name":"scRNA_primary_transcript","termid":"SO:0000012"},{"relation_name":"is_a","term_name":"ncRNA","termid":"SO:0000655"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"scRNA","synonyms":[{"name":"INSDC_feature:ncRNA","type":"broad"},{"name":"INSDC_qualifier:scRNA","type":"exact"},{"name":"small cytoplasmic RNA","type":"exact"}],"termid":"SO:0000013"}


id: PBO:0049743
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hemoglobin subunit gamma 1","termid":"PBO:0049743"}


id: PBO:0000093
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"short chain dehydrogenase (predicted)","termid":"PBO:0000093"}


id: PBO:0042423
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cell division cycle 27 pseudogene 7","termid":"PBO:0042423"}


id: GO:0072732
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of calcium ions.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to starvation","termid":"GO:0009267"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to calcium ion starvation","synonyms":[{"name":"cellular response to calcium starvation","type":"exact"}],"termid":"GO:0072732"}


id: MONDO:0000062
data:
  {"annotated_genes":["SJAG_03497","SJAG_03786","SJAG_04199"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86892],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014050"},{"annotations":[88471],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013783"},{"annotations":[88647],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0975809"}]},"cv_name":"mondo","definition":"A microphthalmia that is not part of a larger syndrome.","definition_xrefs":["MONDO:patterns/isolated"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"microphthalmia","termid":"MONDO:0021129"}],"gene_count":3,"genes_by_uniquename":{"SJAG_03497":null,"SJAG_03786":null,"SJAG_04199":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"isolated microphthalmia","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIMPS:251600","DOID:0080637"],"synonyms":[{"name":"microphthalmia, isolated","type":"exact"},{"name":"nonsyndromic microphthalmia","type":"exact"}],"termid":"MONDO:0000062","terms_by_termid":{"MONDO:0013783":null,"MONDO:0014050":null,"MONDO:0975809":null},"xrefs":{"Monarch":{"xref_id":"0000062"}}}


id: PBO:0061873
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"OOEP antisense RNA 1","termid":"PBO:0061873"}


id: FYPO:0006373
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in one or more heterochromatin islands occurs to a greater extent than normal.","definition_xrefs":["PMID:29214404","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased histone H3-K9 dimethylation during vegetative growth","termid":"FYPO:0000873"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0002274","FYPO:0000002","FYPO:0001985","FYPO:0001320","FYPO:0002494"],"is_obsolete":false,"name":"increased histone H3-K9 dimethylation at heterochromatin island during vegetative growth","synonyms":[{"name":"increased histone H3 K9 dimethylation at heterochromatin island during vegetative growth","type":"exact"},{"name":"increased histone H3-K9 dimethylation at heterochromatin island during mitotic cell cycle","type":"related"},{"name":"increased histone H3K9 dimethylation at heterochromatin island during vegetative growth","type":"exact"},{"name":"increased histone H3K9me2 at heterochromatin island during vegetative growth","type":"exact"},{"name":"increased histone lysine H3 K9 dimethylation at heterochromatin island during vegetative growth","type":"exact"}],"termid":"FYPO:0006373"}


id: MONDO:0022846
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"jaundice, familial obstructive, of infancy","termid":"MONDO:0010634"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"congenital nonhemolytic jaundice","termid":"MONDO:0022846","xrefs":{"Monarch":{"xref_id":"0022846"}}}


id: FYPO:0006469
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature non-coding RNA (ncRNA) measured in a cell is normal (i.e. indistinguishable from wild type). Total ncRNA or a specific ncRNA may be measured.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal RNA level during vegetative growth","termid":"FYPO:0001317"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000257","FYPO:0001312","FYPO:0000002"],"is_obsolete":false,"name":"normal mature ncRNA level","synonyms":[{"name":"normal mature ncRNA accumulation","type":"related"},{"name":"normal mature ncRNA level during mitotic cell cycle","type":"related"},{"name":"normal mature ncRNA level during vegetative growth","type":"exact"},{"name":"normal mature ncRNA transcript level","type":"exact"},{"name":"normal mature non-coding RNA level","type":"exact"},{"name":"normal ncRNA level","type":"broad"}],"termid":"FYPO:0006469"}


id: PBO:0079781
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UDP glucuronosyltransferase family 1 member A2, pseudogene","termid":"PBO:0079781"}


id: MONDO:0018110
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete lethal idiopathic viral infection (obsolete MONDO:0018110)","secondary_identifiers":["Orphanet:35064"],"termid":"MONDO:0018110","xrefs":{"Monarch":{"xref_id":"0018110"}}}


id: MONDO:1011437
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Neurofibromatosis that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cancer or benign tumor, non-human animal","termid":"MONDO:1011305"},{"relation_name":"is_a","term_name":"syndromic disease, non-human animal","termid":"MONDO:1011360"},{"relation_name":"is_a","term_name":"hereditary neurological disease, non-human animal","termid":"MONDO:1012972"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"neurofibromatosis, non-human animal","secondary_identifiers":["OMIA:000716"],"termid":"MONDO:1011437","xrefs":{"Monarch":{"xref_id":"1011437"}}}


id: GO:0017183
data:
  {"annotated_genes":["SJAG_04544","SJAG_04085","SJAG_00251","SJAG_01418","SJAG_02467","SJAG_01058","SJAG_04846","SJAG_00235"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[59922,60252,68210,78771,79614,80863,81868,120658],"is_not":false,"summary":null,"term":"GO:0017183"}]},"cv_name":"biological_process","definition":"The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria.","definition_xrefs":["PMID:20559380","GOC:pde"],"direct_ancestors":[{"relation_name":"is_a","term_name":"peptidyl-histidine modification","termid":"GO:0018202"}],"gene_count":8,"genes_by_uniquename":{"SJAG_00235":null,"SJAG_00251":null,"SJAG_01058":null,"SJAG_01418":null,"SJAG_02467":null,"SJAG_04085":null,"SJAG_04544":null,"SJAG_04846":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"protein histidyl modification to diphthamide","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000041":null,"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-5358493","RESID:AA0040"],"synonyms":[{"name":"peptidyl-diphthamide anabolism from peptidyl-histidine","type":"exact"},{"name":"peptidyl-diphthamide biosynthetic process from peptidyl-histidine","type":"exact"},{"name":"peptidyl-diphthamide formation from peptidyl-histidine","type":"exact"},{"name":"peptidyl-diphthamide synthesis from peptidyl-histidine","type":"exact"}],"termid":"GO:0017183","terms_by_termid":{"GO:0017183":null}}


id: PBO:0090260
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cell wall glucan 1,3-beta-glucosidase Exg3","termid":"PBO:0090260"}


id: GO:0006401
data:
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