# terms

id: MONDO:0006732
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Abnormal movements, including hyperkinesis; hypokinesia; tremor; and dystonia, associated with the use of certain medications or drugs. Muscles of the face, trunk, neck, and extremities are most commonly affected. Tardive dyskinesia refers to abnormal hyperkinetic movements of the muscles of the face, tongue, and neck associated with the use of neuroleptic agents (see antipsychotic agents). (Adams et al., Principles of Neurology, 6th ed, p1199)","definition_xrefs":["MESH:D004409"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nervous system disorder","termid":"MONDO:0005071"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"drug-induced dyskinesia","secondary_identifiers":["SCTID:102448004","UMLS:C0013386","MEDGEN:3935","ICD9:333.99","EFO:1000904","MedDRA:10013916"],"termid":"MONDO:0006732","xrefs":{"Monarch":{"xref_id":"0006732"}}}


id: MONDO:0012960
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any autosomal dominant non-syndromic intellectual disability in which the cause of the disease is a mutation in the SYNGAP1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"infantile epilepsy syndrome","termid":"MONDO:0020071"},{"relation_name":"is_a","term_name":"intellectual disability, autosomal dominant","termid":"MONDO:0100172"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"},{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0005027","MONDO:0000426"],"is_obsolete":false,"name":"intellectual disability, autosomal dominant 5","secondary_identifiers":["GARD:12558","MEDGEN:382611","OMIM:612621","MESH:C567234","DOID:0070035","Orphanet:544254","UMLS:C2675473"],"synonyms":[{"name":"MRD5","type":"exact"},{"name":"SYNGAP1 autosomal dominant non-syndromic intellectual disability","type":"exact"},{"name":"SYNGAP1 gene mutation linked to intellectual disability, schizophrenia and autism","type":"related"},{"name":"SYNGAP1 syndrome","type":"related"},{"name":"SYNGAP1-related NSID","type":"related"},{"name":"SYNGAP1-related developmental and epileptic encephalopathy","type":"exact"},{"name":"SYNGAP1-related non-syndromic intellectual disability","type":"related"},{"name":"autosomal dominant intellectual disability 5","type":"exact"},{"name":"autosomal dominant mental retardation 5","type":"exact"},{"name":"autosomal dominant non-syndromic intellectual disability 5","type":"related"},{"name":"autosomal dominant non-syndromic intellectual disability caused by mutation in SYNGAP1","type":"exact"},{"name":"epilepsy due to SYNGAP mutations","type":"exact"},{"name":"intellectual disability, autosomal dominant 5","type":"exact"},{"name":"intellectual disability, autosomal dominant type 5","type":"exact"},{"name":"mental retardation, autosomal dominant 5","type":"related"},{"name":"mental retardation, autosomal dominant type 5","type":"exact"}],"termid":"MONDO:0012960","xrefs":{"Monarch":{"xref_id":"0012960"}}}


id: PBO:0090832
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"histone H3-H4 chaperone Spt6","termid":"PBO:0090832"}


id: GO:1990161
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A homohexameric protein complex that possesses DNA helicase activity; functions during DNA replication and repair.","definition_xrefs":["GOC:bhm","PMID:17947583"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA helicase complex","termid":"GO:0033202"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"DnaB helicase complex","synonyms":[{"name":"DnaB hexamer","type":"exact"}],"termid":"GO:1990161"}


id: GO:0009325
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"An enzyme complex that catalyzes the formation of nitrate from nitrite with the concomitant reduction of an acceptor.","definition_xrefs":["PMID:2139607"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase complex","termid":"GO:1990204"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"nitrate reductase complex","termid":"GO:0009325"}


id: PBO:0091082
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"candidate Dms1 ortholog, syntenic position (possible gene prediction error)","termid":"PBO:0091082"}


id: PBO:0053928
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1227","termid":"PBO:0053928"}


id: GO:0034336
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to an RNA molecule that has assumed an incorrect conformation.","definition_xrefs":["PMID:10393192","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA binding","termid":"GO:0003723"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003723"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0005488","GO:0003723","GO:0003674"],"is_obsolete":false,"name":"misfolded RNA binding","synonyms":[{"name":"RNA chaperone","type":"related"}],"termid":"GO:0034336"}


id: PBO:0012293
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome segregation impaired protein 1","termid":"PBO:0012293"}


id: GO:0019542
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of propionate, the anion derived from propionic acid.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"propionate metabolic process","termid":"GO:0019541"},{"relation_name":"is_a","term_name":"short-chain fatty acid biosynthetic process","termid":"GO:0051790"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006629","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"propionate biosynthetic process","synonyms":[{"name":"propionate anabolism","type":"exact"},{"name":"propionate biosynthesis","type":"exact"},{"name":"propionate formation","type":"exact"},{"name":"propionate synthesis","type":"exact"}],"termid":"GO:0019542"}


id: PBO:0085626
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein involved in excretion of putrescine and spermidine; putative polyamine transporter in the Golgi or post-Golgi vesicles","termid":"PBO:0085626"}


id: PBO:0000678
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Tim9-Tim10 complex subunit Tim10 (predicted)","termid":"PBO:0000678"}


id: MONDO:0957795
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"arrhythmogenic cardiomyopathy with variable ectodermal abnormalities","secondary_identifiers":["UMLS:C5882696","MEDGEN:1847702","OMIM:620519"],"termid":"MONDO:0957795","xrefs":{"Monarch":{"xref_id":"0957795"}}}


id: PBO:0030915
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_RNA_level_during_vegetative_growth","termid":"PBO:0030915"}


id: SO:0001311
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"N6_N6_dimethyladenosine is a modified adenosine.","direct_ancestors":[{"relation_name":"is_a","term_name":"modified_adenosine","termid":"SO:0001273"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"N6_N6_dimethyladenosine","secondary_identifiers":["RNAMOD:080"],"synonyms":[{"name":"N6,N6-dimethyladenosine","type":"exact"},{"name":"m62A","type":"exact"}],"termid":"SO:0001311"}


id: GO:0004007
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: heavy metal ion(in) + ATP + H2O = heavy metal ion(out) + ADP + phosphate.","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete heavy metal-exporting ATPase activity (obsolete GO:0004007)","synonyms":[{"name":"heavy metal-exporting ATPase activity","type":"exact"}],"termid":"GO:0004007"}


id: GO:0006396
data:
  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id: GO:1904151
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of microglial cell mediated cytotoxicity.","definition_xrefs":["GOC:nc","GO_REF:0000058","GOC:TermGenie","PMID:19100238","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of leukocyte mediated cytotoxicity","termid":"GO:0001912"},{"relation_name":"is_a","term_name":"positive regulation of myeloid leukocyte mediated immunity","termid":"GO:0002888"},{"relation_name":"is_a","term_name":"regulation of microglial cell mediated cytotoxicity","termid":"GO:1904149"},{"relation_name":"positively_regulates","term_name":"microglial cell mediated cytotoxicity","termid":"GO:0090634"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of microglial cell mediated cytotoxicity","synonyms":[{"name":"activation of microglial cell mediated cytotoxicity","type":"narrow"},{"name":"up regulation of microglial cell mediated cytotoxicity","type":"exact"},{"name":"up-regulation of microglial cell mediated cytotoxicity","type":"exact"},{"name":"upregulation of microglial cell mediated cytotoxicity","type":"exact"}],"termid":"GO:1904151"}


id: PBO:0055475
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2908","termid":"PBO:0055475"}


id: PBO:0052449
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"KLF3 antisense RNA 1","termid":"PBO:0052449"}


id: GO:0032484
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"An intracellular signaling cassette in which a small monomeric GTPase of the RaI subfamily relays a signal.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"small GTPase-mediated signal transduction","termid":"GO:0007264"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"Ral protein signal transduction","termid":"GO:0032484"}


id: FYPO:0008354
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of UMP 5'-nucleotidase activity is decreased.","direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal 5'-nucleotidase activity","termid":"FYPO:0008349"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000707"}],"interesting_parent_ids":["FYPO:0000654","FYPO:0001985","FYPO:0000707","FYPO:0000652","FYPO:0000661"],"is_obsolete":false,"name":"decreased UMP 5'-nucleotidase activity","termid":"FYPO:0008354"}


id: PATO:0000764
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A behavioral quality inhering in a bearer by virtue of the bearer's receiving or being subjected to an action without responding or initiating an action in return.","definition_xrefs":["www.answers.com:www.answers.com"],"direct_ancestors":[{"relation_name":"is_a","term_name":"behavioral quality","termid":"PATO:0000186"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"passive","termid":"PATO:0000764"}


id: PR:O94432
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A CUGBP Elav-like family member 4 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO02371","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized RNA-binding protein C660.15 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC660.15","secondary_identifiers":["UniProtKB:O94432"],"synonyms":[{"name":"Spom972h-CELF4","type":"exact"}],"termid":"PR:O94432"}


id: PR:Q9C1W7
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mim1 gene.","definition_xrefs":["UniProtKB:Q9C1W7","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial import protein 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC713.08","synonyms":[{"name":"Spom972h-mim1","type":"exact"}],"termid":"PR:Q9C1W7"}


id: FYPO:0001961
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of DNA topoisomerase II activity is decreased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased catalytic activity","termid":"FYPO:0000663"},{"relation_name":"is_a","term_name":"abnormal DNA topoisomerase II activity","termid":"FYPO:0001960"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000707"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000661","FYPO:0000707","FYPO:0000652","FYPO:0000654"],"is_obsolete":false,"name":"decreased DNA topoisomerase II activity","synonyms":[{"name":"decreased DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity","type":"exact"},{"name":"reduced DNA topoisomerase II activity","type":"exact"}],"termid":"FYPO:0001961"}


id: MOD:01936
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-lysine residue to N6-oleoyl-L-lysine.","definition_xrefs":["RESID:AA0590","PubMed:20942504"],"direct_ancestors":[{"relation_name":"is_a","term_name":"N6-acylated L-lysine","termid":"MOD:01875"},{"relation_name":"is_a","term_name":"N-oleoylated residue","termid":"MOD:02011"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:01155"},{"rel_name":"is_a","termid":"MOD:01875"}],"interesting_parent_ids":["MOD:01875","MOD:01155"],"is_obsolete":false,"name":"N6-oleoyl-L-lysine","synonyms":[{"name":"(2S)-2-amino-6-([(9Z)-octadec-9-enoyl]amino)hexanoic acid","type":"exact"},{"name":"N6-[(9Z)-1-oxo-9-octadecenyl]lysine","type":"exact"},{"name":"N6-oleoyl-L-lysine","type":"exact"}],"termid":"MOD:01936"}


id: GO:0071687
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. The part of the horsetail nucleus where telomeres cluster under the SPB and that leads horsetail movement. The horsetail nucleus is the elongated nucleus which forms during the rapid oscillatory movement at meiotic prophase; characterized in Schizosaccharomyces pombe.","definition_xrefs":["GOC:vw","PMID:15030757","GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete horsetail nucleus leading edge (obsolete GO:0071687)","termid":"GO:0071687"}


id: GO:0005513
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of events in which a calcium ion stimulus is received by a cell and converted into a molecular signal.","definition_xrefs":["GOC:pg"],"direct_ancestors":[{"relation_name":"is_a","term_name":"detection of chemical stimulus","termid":"GO:0009593"},{"relation_name":"is_a","term_name":"response to calcium ion","termid":"GO:0051592"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"detection of calcium ion","synonyms":[{"name":"Ca2+ ion detection","type":"exact"},{"name":"calcium ion detection","type":"exact"},{"name":"calcium ion sensing","type":"exact"},{"name":"detection of Ca2+ ion","type":"exact"}],"termid":"GO:0005513"}


id: MONDO:0018944
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A diverse group of pregnancy-related tumors characterized by excessive proliferation of trophoblasts. Representative examples include hydatidiform mole, gestational choriocarcinoma, and placental site trophoblastic tumor.","definition_xrefs":["NCIT:C4699"],"direct_ancestors":[{"relation_name":"is_a","term_name":"trophoblastic neoplasm","termid":"MONDO:0002872"},{"relation_name":"is_a","term_name":"female reproductive system neoplasm","termid":"MONDO:0021148"},{"relation_name":"is_a","term_name":"pregnancy disorder","termid":"MONDO:0024575"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"gestational trophoblastic neoplasm","secondary_identifiers":["DOID:3590","icd11.foundation:1972855304","SCTID:44782008","Orphanet:59305","NCIT:C3110","MEDGEN:210107","MESH:D006828","UMLS:C1135868","SCTID:609519004","GARD:6498","ICD9:630","MedDRA:10061988"],"synonyms":[{"name":"GTN","type":"exact"},{"name":"GTT","type":"exact"},{"name":"gestational trophoblastic disease","type":"broad"},{"name":"gestational trophoblastic neoplasia","type":"exact"},{"name":"gestational trophoblastic tumor","type":"exact"},{"name":"gestational trophoblastic tumour","type":"exact"},{"name":"hydatidiform mole","type":"related"},{"name":"molar pregnancy","type":"related"}],"termid":"MONDO:0018944","xrefs":{"Monarch":{"xref_id":"0018944"}}}


id: PBO:0016070
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytoplasmic mRNA processing body, zf-CCHC type zinc finger protein (predicted)","termid":"PBO:0016070"}


id: PBO:0043533
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"component of oligomeric golgi complex 1","termid":"PBO:0043533"}


id: GO:0106129
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of store-operated calcium entry.","definition_xrefs":["GOC:BHF_miRNA","GOC:BHF","PMID:23447642","GOC:rph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of calcium ion transport","termid":"GO:0051928"},{"relation_name":"is_a","term_name":"regulation of store-operated calcium entry","termid":"GO:2001256"},{"relation_name":"positively_regulates","term_name":"store-operated calcium entry","termid":"GO:0002115"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0008150"],"is_obsolete":false,"name":"positive regulation of store-operated calcium entry","termid":"GO:0106129"}


id: PBO:0084990
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADPH-dependent aldo-keto reductase; reduces multiple substrates including 2-methylbutyraldehyde and D,L-glyceraldehyde, expression is induced by osmotic and oxidative stress; functionally redundant with other aldo-keto reductases; protein abundance increases in response to DNA replication stress; YPR1 has a paralog, GCY1, that arose from the whole genome duplication; human homolog AKR1B1 can complement yeast null mutant","termid":"PBO:0084990"}


id: MONDO:0019836
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"vascular disorder","termid":"MONDO:0005385"},{"relation_name":"is_a","term_name":"disorder of development or morphogenesis","termid":"MONDO:0021147"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"congenital anomaly of hepatic vein","secondary_identifiers":["GARD:19282","MEDGEN:756237","UMLS:C3163825","Orphanet:95507"],"termid":"MONDO:0019836","xrefs":{"Monarch":{"xref_id":"0019836"}}}


id: GO:0000111
data:
  {"annotated_genes":["SJAG_01049","SJAG_01887"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[74037,74546],"is_not":false,"summary":null,"term":"GO:0000111"}]},"cv_name":"cellular_component","definition":"One of several protein complexes involved in nucleotide-excision repair; possesses damaged DNA binding activity. In S. cerevisiae, it is composed of Rad4p and Rad23p.","definition_xrefs":["PMID:10915862"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleotide-excision repair complex","termid":"GO:0000109"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01049":null,"SJAG_01887":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005634"}],"interesting_parent_ids":["GO:0005634","GO:0032991","GO:0005575"],"is_obsolete":false,"name":"nucleotide-excision repair factor 2 complex","references_by_uniquename":{"GO_REF:0000033":null},"synonyms":[{"name":"NEF2 complex","type":"exact"}],"termid":"GO:0000111","terms_by_termid":{"GO:0000111":null}}


id: FYPO:0006368
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a normal (i.e. indistinguishable from wild type) portion of the centromeric region of the chromosome.","definition_xrefs":["PMID:29214404","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal chromatin organization","termid":"FYPO:0007940"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001312","FYPO:0001320","FYPO:0000002","FYPO:0000257"],"is_obsolete":false,"name":"normal spatial extent of centromeric heterochromatin assembly","synonyms":[{"name":"normal spatial extent of centromeric heterochromatin assembly during mitotic cell cycle","type":"related"},{"name":"normal spatial extent of centromeric heterochromatin assembly during vegetative growth","type":"exact"},{"name":"normal spatial extent of centromeric heterochromatin formation","type":"exact"}],"termid":"FYPO:0006368"}


id: PBO:0051890
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"integrin subunit alpha 1","termid":"PBO:0051890"}


id: PBO:0091363
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small non-coding RNA, stationary phase specific","termid":"PBO:0091363"}


id: PBO:0038707
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"actin gamma 1 pseudogene 1","termid":"PBO:0038707"}


id: GO:0016352
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete insecticide susceptibility/resistance (obsolete GO:0016352)","synonyms":[{"name":"insecticide susceptibility/resistance","type":"exact"}],"termid":"GO:0016352"}


id: PBO:0003211
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RFC-like complex subunit Ctf18","termid":"PBO:0003211"}


id: PBO:0017670
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA-binding protein Rna15","termid":"PBO:0017670"}


id: PBO:0082723
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of the RAM signaling network; is involved in regulation of Ace2p activity and cellular morphogenesis, interacts with protein kinase Cbk1p and also with Kic1p","termid":"PBO:0082723"}


id: PBO:0030874
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_amino_acid_import_during_vegetative_growth","termid":"PBO:0030874"}


id: PBO:0091644
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"O-methyltransferase, human COMT catechol homolog 2","termid":"PBO:0091644"}


id: MONDO:0003637
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare benign lung tumor with perivascular epithelioid cell differentiation. It is composed of round or oval cells with abundant clear or eosinophilic cytoplasm and distinct cell borders. The vast majority of patients are asymptomatic and the tumors are discovered incidentally. Excision is curative.","definition_xrefs":["NCIT:C38152"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lung benign neoplasm","termid":"MONDO:0002732"},{"relation_name":"is_a","term_name":"benign PEComa","termid":"MONDO:0020581"},{"relation_name":"is_a","term_name":"lung PEComa","termid":"MONDO:0020588"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"clear cell-sugar-tumor of the lung","secondary_identifiers":["DOID:5763","UMLS:C1333065","MEDGEN:232370"],"synonyms":[{"name":"CCSTL","type":"exact"},{"name":"Sugar tumor","type":"exact"},{"name":"Sugar tumour","type":"exact"},{"name":"clear cell-Sugar-tumor of lung","type":"exact"},{"name":"clear cell-Sugar-tumor of the lung","type":"exact"},{"name":"lung clear cell tumor","type":"exact"},{"name":"lung clear cell tumour","type":"exact"},{"name":"lung clear cell-sugar-tumor","type":"related"}],"termid":"MONDO:0003637","xrefs":{"Monarch":{"xref_id":"0003637"}}}


id: PBO:0080834
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tyrosyl-tRNA synthetase 2","termid":"PBO:0080834"}


id: MONDO:0014324
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any pachyonychia congenita in which the cause of the disease is a mutation in the KRT6A gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pachyonychia congenita","termid":"MONDO:0016471"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"pachyonychia congenita 3","secondary_identifiers":["MEDGEN:811523","UMLS:C3714948","GARD:16005","OMIM:615726"],"synonyms":[{"name":"KRT6A pachyonychia congenita","type":"exact"},{"name":"PC3","type":"related"},{"name":"pachyonychia congenita 3","type":"exact"},{"name":"pachyonychia congenita caused by mutation in KRT6A","type":"exact"},{"name":"pachyonychia congenita type 3","type":"exact"}],"termid":"MONDO:0014324","xrefs":{"Monarch":{"xref_id":"0014324"}}}


id: GO:0008197
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete yolk protein (obsolete GO:0008197)","synonyms":[{"name":"yolk protein","type":"exact"}],"termid":"GO:0008197"}


id: GO:0051042
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-independent cell-cell adhesion.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cell-cell adhesion","termid":"GO:0022408"},{"relation_name":"is_a","term_name":"regulation of calcium-independent cell-cell adhesion","termid":"GO:0051040"},{"relation_name":"negatively_regulates","term_name":"calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules","termid":"GO:0016338"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0007155"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0007155"}],"interesting_parent_ids":["GO:0007155","GO:0008150"],"is_obsolete":false,"name":"negative regulation of calcium-independent cell-cell adhesion","synonyms":[{"name":"down regulation of calcium-independent cell-cell adhesion","type":"exact"},{"name":"down-regulation of calcium-independent cell-cell adhesion","type":"exact"},{"name":"downregulation of calcium-independent cell-cell adhesion","type":"exact"},{"name":"inhibition of calcium-independent cell-cell adhesion","type":"narrow"}],"termid":"GO:0051042"}


id: GO:1905043
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of epithelium regeneration.","definition_xrefs":["GOC:rph","GOC:TermGenie","GO_REF:0000058","GOC:BHF","PMID:23221517","GOC:BHF_miRNA"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of developmental growth","termid":"GO:0048639"},{"relation_name":"is_a","term_name":"regulation of epithelium regeneration","termid":"GO:1905041"},{"relation_name":"positively_regulates","term_name":"epithelium regeneration","termid":"GO:1990399"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of epithelium regeneration","synonyms":[{"name":"activation of epithelium regeneration","type":"narrow"},{"name":"activation of regeneration of epithelium","type":"narrow"},{"name":"positive regulation of regeneration of epithelium","type":"exact"},{"name":"up regulation of epithelium regeneration","type":"exact"},{"name":"up regulation of regeneration of epithelium","type":"exact"},{"name":"up-regulation of epithelium regeneration","type":"exact"},{"name":"up-regulation of regeneration of epithelium","type":"exact"},{"name":"upregulation of epithelium regeneration","type":"exact"},{"name":"upregulation of regeneration of epithelium","type":"exact"}],"termid":"GO:1905043"}


id: GO:0060942
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a neural crest cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.","definition_xrefs":["GOC:mtg_heart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cardiac fibroblast cell differentiation","termid":"GO:0060935"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"neural crest-derived cardiac fibroblast cell differentiation","termid":"GO:0060942"}


id: PR:O13698
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A malonyl-CoA-acyl carrier protein transacylase, mitochondrial that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO01650","PANTHER:PTHR10982:SF4","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"malonyl CoA-acyl carrier protein transacylase, mitochondrial (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC11G7.05c","secondary_identifiers":["UniProtKB:O13698"],"synonyms":[{"name":"MCT (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-MCAT","type":"exact"},{"name":"malonyl-CoA:ACP transferase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O13698"}


id: MONDO:0022643
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A carcinoma that involves the laryngeal vocal fold.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glottis carcinoma","termid":"MONDO:0002355"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"carcinoma of the vocal tract","synonyms":[{"name":"carcinoma of laryngeal vocal fold","type":"exact"},{"name":"laryngeal vocal fold carcinoma","type":"exact"}],"termid":"MONDO:0022643","xrefs":{"Monarch":{"xref_id":"0022643"}}}


id: PBO:0090694
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial proton-transporting ATP synthase inhibitor Inh1","termid":"PBO:0090694"}


id: FYPO:0005228
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing doxorubicin.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal vegetative cell population growth","termid":"FYPO:0001357"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0002058"}],"interesting_parent_ids":["FYPO:0002057","FYPO:0000003","FYPO:0002058","FYPO:0002060","FYPO:0000257","FYPO:0000139"],"is_obsolete":false,"name":"normal growth on doxorubicin","synonyms":[{"name":"normal cell population growth in presence of doxorubicin","type":"exact"},{"name":"normal cell population growth on doxorubicin","type":"exact"},{"name":"normal cellular response to doxorubicin","type":"related"},{"name":"normal vegetative cell population growth on doxorubicin","type":"exact"}],"termid":"FYPO:0005228"}


id: PBO:0031659
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_pseudohyphal_growth","termid":"PBO:0031659"}


id: MONDO:1011961
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"musculoskeletal system disorder, non-human animal","termid":"MONDO:1011335"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"brachygnathia, cardiomegaly and renal hypoplasia syndrome, non-human animal","secondary_identifiers":["OMIA:001595"],"termid":"MONDO:1011961","xrefs":{"Monarch":{"xref_id":"1011961"}}}


id: GO:1904103
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of convergent extension involved in gastrulation.","definition_xrefs":["GO_REF:0000058","GOC:TermGenie","PMID:24892953","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of morphogenesis of an epithelium","termid":"GO:1905330"},{"relation_name":"regulates","term_name":"convergent extension involved in gastrulation","termid":"GO:0060027"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of convergent extension involved in gastrulation","termid":"GO:1904103"}


id: PBO:0082862
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Core Sm protein Sm D1; part of heteroheptameric complex (with Smb1p, Smd2p, Smd3p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; relocalizes to the cytosol in response to hypoxia; homolog of human Sm D1; protein abundance increases in response to DNA replication stress","termid":"PBO:0082862"}


id: GO:0016858
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Racemase and epimerase activity on compounds other than amino acids, hydroxy acids, carbohydrates or their derivatives.","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete racemase and epimerase activity, acting on other compounds (obsolete GO:0016858)","synonyms":[{"name":"racemase and epimerase activity, acting on other compounds","type":"exact"}],"termid":"GO:0016858"}


id: FYPO:0004818
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of small RNA (such as siRNA) derived from antisense transcription of transfer RNA genes measured in a cell is lower than normal.","definition_xrefs":["PomBase:mah","PMID:25417108"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased antisense RNA level","termid":"FYPO:0004816"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0005447","FYPO:0006551","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"decreased tDNA antisense small RNA level","synonyms":[{"name":"decreased accumulation of tDNA antisense small RNAs","type":"related"},{"name":"decreased antisense small RNA at tDNA","type":"exact"},{"name":"decreased antisense transcription-derived small RNA level at tDNA","type":"exact"},{"name":"decreased tDNA antisense small RNA accumulation","type":"related"},{"name":"decreased tDNA antisense small RNA level during mitotic cell cycle","type":"related"},{"name":"decreased tDNA antisense small RNA level during vegetative growth","type":"exact"},{"name":"reduced tDNA antisense small RNA level","type":"exact"}],"termid":"FYPO:0004818"}


id: PBO:0111757
data:
  {"annotation_feature_type":"gene","cv_name":"pombase_family_or_domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphoinositide 3-kinase family protein","termid":"PBO:0111757"}


id: GO:0044448
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. Any constituent part of the cell cortex, the region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.","definition_xrefs":["GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete cell cortex part (obsolete GO:0044448)","termid":"GO:0044448"}


id: MONDO:0009869
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Pierre-Robin syndrome (or Pierre-Robin sequence) is characterized by triad of orofacial morphological anomalies consisting of retrognathism, glossoptosis and a posterior median velopalatal cleft.","definition_xrefs":["Orphanet:718"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"excluded_subClassOf","term_name":"obsolete syndrome or malformation associated with head and neck malformations (obsolete MONDO:0015501)","termid":"MONDO:0015501"},{"relation_name":"is_a","term_name":"eye disorder","termid":"MONDO:0005328"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"isolated Pierre-Robin syndrome","secondary_identifiers":["icd11.foundation:136361299","NCIT:C85010","SCTID:4602007","UMLS:C0031900","GARD:4347","NORD:1579","OMIM:261800","MESH:D010855","MEDGEN:19310"],"synonyms":[{"name":"PRBNS","type":"related"},{"name":"Pierre Robin Sequence","type":"exact"},{"name":"Pierre Robin sequence","type":"related"},{"name":"Pierre Robin syndrome","type":"related"},{"name":"Pierre Robin syndrome skeletal dysplasia polydactyly","type":"related"},{"name":"Pierre Robin's sequence","type":"related"},{"name":"Pierre Robins sequence","type":"related"},{"name":"Pierre-Robin syndrome","type":"related"},{"name":"Robin sequence","type":"related"},{"name":"Robin syndrome, Pierre","type":"related"},{"name":"glossoptosis, micrognathia, and cleft palate","type":"related"},{"name":"isolated Pierre Robin sequence","type":"exact"},{"name":"isolated Pierre Robin syndrome","type":"related"},{"name":"isolated Pierre-Robin syndrome","type":"exact"},{"name":"sequence, Pierre Robin","type":"related"},{"name":"sequence, Pierre Robin's","type":"related"},{"name":"sequence, Robin","type":"related"},{"name":"syndrome, Pierre Robin","type":"related"},{"name":"syndrome, Pierre-Robin","type":"related"}],"termid":"MONDO:0009869","xrefs":{"Monarch":{"xref_id":"0009869"}}}


id: GO:0008667
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + NAD+ = 2,3-dihydroxybenzoate + H+ + NADH.","definition_xrefs":["EC:1.3.1.28","RHEA:23824"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor","termid":"GO:0016628"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity","secondary_identifiers":["KEGG_REACTION:R01505","MetaCyc:DHBDEHYD-RXN"],"synonyms":[{"name":"2,3-DHB dehydrogenase activity","type":"related"},{"name":"2,3-dihydro-2,3-dihydroxybenzoate:NAD+ oxidoreductase activity","type":"related"}],"termid":"GO:0008667"}


id: PR:O94455
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC1687.14c gene.","definition_xrefs":["PRO:DNx","UniProtKB:O94455"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized calcium-binding protein C1687.14c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1687.14c","synonyms":[{"name":"Spom972h-SPAC1687.14c","type":"exact"}],"termid":"PR:O94455"}


id: PBO:0028305
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_protein_phosphorylation_during_mitotic_G1_phase","termid":"PBO:0028305"}


id: GO:0018954
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving pentaerythritol tetranitrate, C(CH2-O-NO2)4, a substance produced for use as an explosive and a vasodilator.","definition_xrefs":["UM-BBD_pathwayID:petn"],"direct_ancestors":[{"relation_name":"is_a","term_name":"xenobiotic metabolic process","termid":"GO:0006805"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"pentaerythritol tetranitrate metabolic process","synonyms":[{"name":"pentaerythritol tetranitrate metabolism","type":"exact"}],"termid":"GO:0018954"}


id: MONDO:0010517
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any primary ciliary dyskinesia in which the cause of the disease is a mutation in the PIH1D3 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"primary ciliary dyskinesia","termid":"MONDO:0016575"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ciliary dyskinesia, primary, 36, X-linked","secondary_identifiers":["GARD:15280","MEDGEN:1393107","UMLS:C4478372","DOID:0111850","OMIM:300991"],"synonyms":[{"name":"CILD36","type":"exact"},{"name":"PIH1D3 primary ciliary dyskinesia","type":"exact"},{"name":"ciliary dyskinesia, primary, 36, X-linked","type":"exact"},{"name":"ciliary dyskinesia, primary, 36, X-linked, X-linked recessive","type":"exact"},{"name":"ciliary dyskinesia, primary, 36, X-linked; CILD36","type":"exact"},{"name":"ciliary dyskinesia, primary, 36, with or without situs inversus","type":"related"},{"name":"primary ciliary dyskinesia caused by mutation in PIH1D3","type":"exact"}],"termid":"MONDO:0010517","xrefs":{"Monarch":{"xref_id":"0010517"}}}


id: FYPO:0001567
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-histidine measured in a cell is higher than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased cellular amino acid level","termid":"FYPO:0003986"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320","FYPO:0001985"],"is_obsolete":false,"name":"increased cellular histidine level","synonyms":[{"name":"increased cellular L-histidine level","type":"exact"},{"name":"increased cellular histidine level during mitotic cell cycle","type":"related"},{"name":"increased cellular histidine level during vegetative growth","type":"exact"},{"name":"increased histidine accumulation","type":"related"}],"termid":"FYPO:0001567"}


id: PBO:0061569
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"N-terminal asparagine amidase pseudogene 3","termid":"PBO:0061569"}


id: PBO:0059529
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrially encoded tRNA-Ala (GCN)","termid":"PBO:0059529"}


id: PBO:0040949
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BCL2 interacting protein 3 pseudogene 20","termid":"PBO:0040949"}


id: MONDO:0001352
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A malignant neoplasm involving the round ligament of uterus.","direct_ancestors":[{"relation_name":"is_a","term_name":"musculoskeletal system cancer","termid":"MONDO:0000637"},{"relation_name":"is_a","term_name":"uterine adnexa cancer","termid":"MONDO:0001351"},{"relation_name":"is_a","term_name":"peritoneum cancer","termid":"MONDO:0002087"},{"relation_name":"is_a","term_name":"ligament disorder","termid":"MONDO:0045044"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"round ligament malignant neoplasm","secondary_identifiers":["UMLS:C0346867","SCTID:188204000","DOID:11748","ICD9:183.5","MEDGEN:577692","ICD10CM:C57.2"],"synonyms":[{"name":"cancer of round ligament of uterus","type":"exact"},{"name":"malignant neoplasm of round ligament","type":"exact"},{"name":"malignant neoplasm of round ligament of uterus","type":"exact"},{"name":"malignant round ligament of uterus neoplasm","type":"exact"},{"name":"round ligament of uterus cancer","type":"exact"}],"termid":"MONDO:0001352","xrefs":{"Monarch":{"xref_id":"0001352"}}}


id: PBO:0061770
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"OBI1 antisense RNA 1","termid":"PBO:0061770"}


id: GO:0051670
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the endohydrolysis of 2,1-beta-D-fructosidic linkages in inulin.","definition_xrefs":["EC:3.2.1.7"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, hydrolyzing O-glycosyl compounds","termid":"GO:0004553"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016798"}],"interesting_parent_ids":["GO:0016787","GO:0016798","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"inulinase activity","secondary_identifiers":["MetaCyc:3.2.1.7-RXN"],"synonyms":[{"name":"2,1-beta-D-fructan fructanohydrolase activity","type":"exact"},{"name":"endo-inulinase activity","type":"exact"},{"name":"exoinulinase activity","type":"exact"},{"name":"indoinulinase activity","type":"exact"},{"name":"inulase activity","type":"exact"}],"termid":"GO:0051670"}


id: GO:0061925
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that reduces the frequency, rate or extent of the formation of radial glial scaffolds. The scaffolds are used as a substrate for the radial migration of cells.","definition_xrefs":["PMID:22076441"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cell morphogenesis","termid":"GO:0010771"},{"relation_name":"is_a","term_name":"regulation of formation of radial glial scaffolds","termid":"GO:0061924"},{"relation_name":"negatively_regulates","term_name":"formation of radial glial scaffolds","termid":"GO:0021943"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of formation of radial glial scaffolds","synonyms":[{"name":"negative regulation of Bergmann fiber biosynthesis","type":"related"},{"name":"negative regulation of Bergmann fiber formation","type":"related"},{"name":"negative regulation of radial glial scaffold formation","type":"exact"}],"termid":"GO:0061925"}


id: GO:0001584
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. A G protein-coupled receptor that is structurally/functionally related to the rhodopsin receptor.","definition_xrefs":["GOC:dph","GOC:tb","IUPHAR_GPCR:1505","GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete rhodopsin-like receptor activity (obsolete GO:0001584)","synonyms":[{"name":"Class A G protein coupled receptor","type":"exact"},{"name":"Class A G-protein coupled receptor","type":"exact"},{"name":"Class A GPCR","type":"exact"},{"name":"class A orphan receptor activity","type":"exact"},{"name":"rhodopsin-like receptor activity","type":"exact"}],"termid":"GO:0001584"}


id: PBO:0073777
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 4 member 10","termid":"PBO:0073777"}


id: PBO:0068803
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 40, pseudogene","termid":"PBO:0068803"}


id: PATO:0001600
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A rotation quality inhering in a bearer by virtue of being rotated towards the rear of organism.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"rotated","termid":"PATO:0001599"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"posteriorly rotated","termid":"PATO:0001600"}


id: GO:0001118
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The disaggregation of a transcription ternary complex, composed of RNA polymerase, template DNA, and an RNA transcript, into its constituent components.","definition_xrefs":["GOC:txnOH"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-DNA-RNA complex disassembly","termid":"GO:0001117"},{"relation_name":"part_of","term_name":"DNA-templated transcription termination","termid":"GO:0006353"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0006351"},{"rel_name":"part_of","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0010467","GO:0006351","GO:0008150"],"is_obsolete":false,"name":"transcription ternary complex disassembly","synonyms":[{"name":"transcription protein-DNA-RNA complex disassembly","type":"exact"}],"termid":"GO:0001118"}


id: PBO:0028453
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-elongated_multinucleate_cell","termid":"PBO:0028453"}


id: MONDO:0043176
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"inborn disorder of purine or pyrimidine metabolism","termid":"MONDO:0019254"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0019254"}],"interesting_parent_ids":["MONDO:0019254","MONDO:0005066"],"is_obsolete":false,"name":"phosphoribosylpyrophosphate synthetase deficiency","secondary_identifiers":["SCTID:124343001","MESH:C535995","MEDGEN:220944","MESH:C537897","UMLS:C1291401","HGNC:9462"],"synonyms":[{"name":"PRPP synthetase deficiency","type":"related"},{"name":"deafness hyperuricemia neurologic ataxia","type":"exact"}],"termid":"MONDO:0043176","xrefs":{"Monarch":{"xref_id":"0043176"}}}


id: GO:0100041
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates pseudohyphal growth.","definition_xrefs":["GOC:obol","GOC:cjm"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of pseudohyphal growth by transcription from RNA polymerase II promoter (obsolete GO:0100041)","termid":"GO:0100041"}


id: MONDO:0005444
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete leishmaniasis (obsolete MONDO:0005444)","termid":"MONDO:0005444","xrefs":{"Monarch":{"xref_id":"0005444"}}}


id: MOD:01550
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces a hydrogen atom of a protein N-terminal with the Applied Biosystems iTRAQ8plex-116 reporter+balance group.","definition_xrefs":["Unimod:730#N-term"],"direct_ancestors":[{"relation_name":"is_a","term_name":"iTRAQ8plex-116 reporter+balance reagent acylated residue","termid":"MOD:01549"},{"relation_name":"is_a","term_name":"iTRAQ8plex reporter+balance reagent acylated N-terminal","termid":"MOD:01712"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"iTRAQ8plex-116 reporter+balance reagent acylated N-terminal","synonyms":[{"name":"(4-methylpiperazin-1-yl)acetyl","type":"exact"},{"name":"Applied Biosystems iTRAQ(TM) multiplexed quantitation chemistry","type":"related"},{"name":"Representative mass and accurate mass for 113, 114, 116 & 117","type":"related"},{"name":"iTRAQ8plex","type":"related"},{"name":"iTRAQ8plex:13C(7)15N(1)","type":"related"}],"termid":"MOD:01550"}


id: PR:000037030
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the rho3 gene in Schizosaccharomyces pombe.","definition_xrefs":["PRO:DAN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein","termid":"PR:000000001"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GTP-binding protein rho3 (Schizosaccharomyces pombe)","pombase_gene_id":"SPAC23C4.08","synonyms":[{"name":"Spom-rho3","type":"exact"}],"termid":"PR:000037030"}


id: GO:0010007
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A heterotrimeric enzyme complex composed of three subunits, all of which are required for enzyme activity, which catalyzes the chelation of Mg by proto IX in an ATP-dependent manner.","definition_xrefs":["PMID:11842180"],"direct_ancestors":[{"relation_name":"is_a","term_name":"catalytic complex","termid":"GO:1902494"},{"relation_name":"part_of","term_name":"chloroplast","termid":"GO:0009507"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0005737","GO:0032991"],"is_obsolete":false,"name":"magnesium chelatase complex","termid":"GO:0010007"}


id: PBO:0046786
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"enhancer of zeste 1 polycomb repressive complex 2 subunit","termid":"PBO:0046786"}


id: MONDO:0000945
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Impaired venous blood flow or venous return (venous stasis), usually caused by inadequate venous valves. Venous insufficiency often occurs in the legs, and is associated with edema and sometimes with venous stasis ulcers at the ankle.","definition_xrefs":["MESH:D014689"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vein disorder","termid":"MONDO:0004634"},{"relation_name":"is_a","term_name":"vascular insufficiency disorder","termid":"MONDO:0020674"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"venous insufficiency","secondary_identifiers":["SCTID:20696009","HP:0005293","ICD9:459.81","MEDGEN:21841","UMLS:C0042485","DOID:10128"],"synonyms":[{"name":"peripheral venous insufficiency","type":"narrow"},{"name":"venous insufficiency","type":"exact"},{"name":"venous insufficiency (disease)","type":"exact"}],"termid":"MONDO:0000945","xrefs":{"Monarch":{"xref_id":"0000945"}}}


id: GO:0009374
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to biotin (cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid), the (+) enantiomer of which is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.","definition_xrefs":["GOC:jl","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vitamin binding","termid":"GO:0019842"},{"relation_name":"is_a","term_name":"amide binding","termid":"GO:0033218"},{"relation_name":"is_a","term_name":"monocarboxylic acid binding","termid":"GO:0033293"},{"relation_name":"is_a","term_name":"heterocyclic compound binding","termid":"GO:1901363"},{"relation_name":"is_a","term_name":"sulfur compound binding","termid":"GO:1901681"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0005488","GO:0003674"],"is_obsolete":false,"name":"biotin binding","synonyms":[{"name":"vitamin B7 binding","type":"exact"},{"name":"vitamin H binding","type":"exact"}],"termid":"GO:0009374"}


id: PBO:0083239
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; encoded within the 35S rRNA gene on the opposite strand","termid":"PBO:0083239"}


id: GO:1900193
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of oocyte maturation.","definition_xrefs":["GOC:kmv","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cell maturation","termid":"GO:1903429"},{"relation_name":"is_a","term_name":"regulation of reproductive process","termid":"GO:2000241"},{"relation_name":"regulates","term_name":"oocyte maturation","termid":"GO:0001556"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of oocyte maturation","termid":"GO:1900193"}


id: PBO:0084253
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Inositol hexakisphosphate and inositol heptakisphosphate kinase; generation of high energy inositol pyrophosphates by Kcs1p is required for many processes such as vacuolar biogenesis, stress response, RNA polymerase I-mediated rRNA transcription and telomere maintenance; inositol hexakisphosphate is also known as IP6; inositol heptakisphosphate is also known as IP7","termid":"PBO:0084253"}


id: PBO:0074021
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 25 member 14 pseudogene 1","termid":"PBO:0074021"}


id: MONDO:0100402
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any acute myeloid leukemia that has the chromosomal anomaly del(13q14-q21). (A cytogenetic abnormality that refers to deletion of chromosome bands 14-21 on the long arm of chromosome 13.)","definition_xrefs":["NCIT:C168770"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acute myeloid leukemia","termid":"MONDO:0018874"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0004992","MONDO:0005046"],"is_obsolete":false,"name":"acute myeloid leukemia, del(13q14-q21)","synonyms":[{"name":"AML, 13q14-q21 Deletion","type":"exact"},{"name":"AML, del(13)(q14-q21)","type":"exact"},{"name":"AML, del(13)(q14q21)","type":"exact"},{"name":"AML, del(13q)(13q14-21)","type":"exact"},{"name":"AML, del(13q14-q21)","type":"exact"}],"termid":"MONDO:0100402","xrefs":{"Monarch":{"xref_id":"0100402"}}}


id: PBO:0056451
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microtubule affinity regulating kinase 3 pseudogene 3","termid":"PBO:0056451"}


id: GO:0090229
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light.","definition_xrefs":["GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of signal transduction","termid":"GO:0009968"},{"relation_name":"is_a","term_name":"regulation of red or far-red light signaling pathway","termid":"GO:0090227"},{"relation_name":"negatively_regulates","term_name":"red or far-red light signaling pathway","termid":"GO:0010017"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"negative regulation of red or far-red light signaling pathway","synonyms":[{"name":"negative regulation of phytochrome signaling pathway","type":"exact"},{"name":"negative regulation of red or far-red light signalling pathway","type":"exact"}],"termid":"GO:0090229"}


id: MONDO:0012176
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Emanuel syndrome is a constitutional genomic disorder due to the presence of a supernumerary derivative 22 chromosome and characterized by severe intellectual disability, characteristic facial dysmorphism (micrognathia, hooded eyelids, upslanting downslanting parebral fissures, deep set eyes, low hanging columnella and long philtrum), congenital heart defects and kidney abnormalities.","definition_xrefs":["Orphanet:96170"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Emanuel syndrome","secondary_identifiers":["ICD9:758.5","OMIM:609029","UMLS:C1836929","MESH:C535733","NANDO:1200689","MEDGEN:323030","SCTID:702417004","GARD:9835"],"synonyms":[{"name":"Der(22)t(11;22) syndrome","type":"exact"},{"name":"Ehlers-Danlos syndrome, classic-like, 1","type":"related"},{"name":"Emanuel syndrome","type":"exact"},{"name":"supernumerary Der(22)T(11","type":"related"},{"name":"supernumerary der(22) syndrome","type":"exact"},{"name":"supernumerary der(22),t(11;22) syndrome","type":"related"}],"termid":"MONDO:0012176","xrefs":{"Monarch":{"xref_id":"0012176"}}}


id: PBO:0111936
data:
  {"annotation_feature_type":"gene","cv_name":"pombase_family_or_domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PKC subfamily","termid":"PBO:0111936"}


id: MONDO:0002398
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign adenofibroma characterized by the presence of epithelial cells which contain intracytoplasmic mucin and a fibrotic stroma. A representative example is the ovarian mucinous adenofibroma. Cases with epithelial atypia described in the ovary lacking stromal invasion are designated as borderline mucinous adenofibromas and have a low grade malignant potential.","definition_xrefs":["NCIT:C8978"],"direct_ancestors":[{"relation_name":"is_a","term_name":"adenofibroma","termid":"MONDO:0006071"},{"relation_name":"is_a","term_name":"mucinous neoplasm","termid":"MONDO:0024338"},{"relation_name":"is_a","term_name":"benign epithelial neoplasm","termid":"MONDO:0036976"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mucinous adenofibroma","secondary_identifiers":["DOID:2700","MEDGEN:83158","UMLS:C0334499","ICDO:9015/0"],"synonyms":[{"name":"mucinous adenofibroma","type":"exact"}],"termid":"MONDO:0002398","xrefs":{"Monarch":{"xref_id":"0002398"}}}


id: MONDO:0014878
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"patent ductus arteriosus","termid":"MONDO:0011827"},{"relation_name":"is_a","term_name":"TFAP2B-related congenital heart disease spectrum disorder","termid":"MONDO:1010098"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"patent ductus arteriosus 2","secondary_identifiers":["MEDGEN:924886","OMIM:617035","GARD:18489","UMLS:C4284595"],"synonyms":[{"name":"PDA2","type":"exact"},{"name":"patent ductus arteriosus 2","type":"exact"},{"name":"patent ductus arteriosus 2; PDA2","type":"exact"},{"name":"patent ductus arteriosus type 2","type":"exact"}],"termid":"MONDO:0014878","xrefs":{"Monarch":{"xref_id":"0014878"}}}


id: PBO:0045109
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DMD antisense RNA 3","termid":"PBO:0045109"}


id: PBO:0076432
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TATA-box binding protein associated factor 11 like 8","termid":"PBO:0076432"}


id: MONDO:0014485
data:
  {"annotated_genes":["SJAG_04084"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88834],"is_not":false,"summary":null,"term":"MONDO:0014485"}]},"cv_name":"mondo","definition":"Any pontocerebellar hypoplasia type 1 in which the cause of the disease is a mutation in the EXOSC8 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pontocerebellar hypoplasia type 1","termid":"MONDO:0016396"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04084":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0020022"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0037792"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0037792","MONDO:0005559","MONDO:0020022","MONDO:0005066","MONDO:0006025"],"is_obsolete":false,"name":"pontocerebellar hypoplasia, type 1C","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:16058","MEDGEN:863597","UMLS:C4015160","DOID:0112334","OMIM:616081"],"synonyms":[{"name":"EXOSC8 pontocerebellar hypoplasia type 1","type":"exact"},{"name":"PCH1C","type":"related"},{"name":"hypomyelination with spinal muscular atrophy and cerebellar hypoplasia","type":"related"},{"name":"pontocerebellar hypoplasia type 1 caused by mutation in EXOSC8","type":"exact"},{"name":"pontocerebellar hypoplasia, type 1C","type":"exact"}],"termid":"MONDO:0014485","terms_by_termid":{"MONDO:0014485":null},"xrefs":{"Monarch":{"xref_id":"0014485"}}}


id: PBO:0084817
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial protein of unknown function; required for respiratory growth; mutant accumulates less glycogen than does wild type; null mutation results in a decrease in plasma membrane electron transport; YIL060W is not an essential gene","termid":"PBO:0084817"}


id: GO:0044632
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents, or reduces the rate of complement activation by the lectin pathway, in a different organism.","definition_xrefs":["GOC:jl","PMID:20837040"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of complement activation, lectin pathway in another organism (obsolete GO:0044632)","synonyms":[{"name":"negative regulation of complement activation, lectin pathway in other organism","type":"exact"}],"termid":"GO:0044632"}


id: FYPO:0002386
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin at centromere outer repeat regions is decreased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased protein localization to chromatin at centromere outer repeat","termid":"FYPO:0006818"},{"relation_name":"is_a","term_name":"decreased protein localization to pericentric heterochromatin","termid":"FYPO:0008422"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000138","FYPO:0000002","FYPO:0001985","FYPO:0001320"],"is_obsolete":false,"name":"decreased protein localization to pericentric heterochromatin at centromere outer repeat","synonyms":[{"name":"deceased protein localization to heterochromatin at centromere otr","type":"exact"},{"name":"decreased protein localisation to heterochromatin at centromere outer repeat","type":"exact"},{"name":"decreased protein localization to centromere outer repeat heterochromatin","type":"exact"},{"name":"decreased protein localization to heterochromatin at centromere outer repeat during vegetative growth","type":"exact"},{"name":"decreased protein localization to heterochromatin at centromeric outer repeat region","type":"exact"},{"name":"decreased protein localization to heterochromatin at pericentromeric region","type":"related"}],"termid":"FYPO:0002386"}


id: PBO:0061721
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NUT family member 2F","termid":"PBO:0061721"}


id: GO:0021575
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.","definition_xrefs":["GO_REF:0000021","GOC:dph","GOC:jid","ISBN:0838580343","GOC:cls","GOC:dgh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure morphogenesis","termid":"GO:0009653"},{"relation_name":"part_of","term_name":"hindbrain development","termid":"GO:0030902"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"hindbrain morphogenesis","synonyms":[{"name":"rhombencephalon morphogenesis","type":"related"}],"termid":"GO:0021575"}


id: PBO:0089482
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"arrestin-related substrate adaptor for RhoGEF, Art1","termid":"PBO:0089482"}


id: PBO:0077955
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Ala (anticodon AGC) 12-2","termid":"PBO:0077955"}


id: PBO:0030772
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_growth_on_thiabendazole","termid":"PBO:0030772"}


id: PBO:0075203
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nuclear ribonucleoprotein polypeptide G pseudogene 15","termid":"PBO:0075203"}


id: MOD:00664
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces a residue L-enantiomer (stereoisomer) with a D-enantiomer or with a different diastereomeric isomer.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein modification categorized by chemical process","termid":"MOD:01156"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"stereoisomerized residue","synonyms":[{"name":"D-Res","type":"exact"}],"termid":"MOD:00664"}


id: PBO:0116848
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"plasma membrane beta-glucan biosynthesis protein Max1","termid":"PBO:0116848"}


id: MONDO:0013394
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"disorder of development or morphogenesis","termid":"MONDO:0021147"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"porencephaly-microcephaly-bilateral congenital cataract syndrome","secondary_identifiers":["GARD:17380","Orphanet:306547","OMIM:613730","MEDGEN:462350","UMLS:C3151000"],"synonyms":[{"name":"HDBSCC","type":"related"},{"name":"hemorrhagic destruction of the brain, subependymal calcification, and cataracts","type":"related"},{"name":"porencephaly-microcephaly-bilateral congenital cataract syndrome","type":"exact"}],"termid":"MONDO:0013394","xrefs":{"Monarch":{"xref_id":"0013394"}}}


id: GO:0031336
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of sulfur amino acid metabolic process","termid":"GO:0031335"},{"relation_name":"is_a","term_name":"negative regulation of sulfur metabolic process","termid":"GO:0051175"},{"relation_name":"is_a","term_name":"negative regulation of small molecule metabolic process","termid":"GO:0062014"},{"relation_name":"negatively_regulates","term_name":"sulfur amino acid metabolic process","termid":"GO:0000096"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006790"},{"rel_name":"negatively_regulates","termid":"GO:0006790"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"negatively_regulates","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0006790","GO:0044281"],"is_obsolete":false,"name":"negative regulation of sulfur amino acid metabolic process","synonyms":[{"name":"down regulation of sulfur amino acid metabolic process","type":"exact"},{"name":"down-regulation of sulfur amino acid metabolic process","type":"exact"},{"name":"downregulation of sulfur amino acid metabolic process","type":"exact"},{"name":"inhibition of sulfur amino acid metabolic process","type":"narrow"},{"name":"negative regulation of sulfur amino acid metabolism","type":"exact"}],"termid":"GO:0031336"}


id: PBO:0110373
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HNRNPA3 pseudogene 17","termid":"PBO:0110373"}


id: GO:0030117
data:
  {"annotated_genes":["SJAG_00906","SJAG_02349","SJAG_02453","SJAG_00072","SJAG_04070","SJAG_02539","SJAG_04569","SJAG_03153","SJAG_02234","SJAG_02282","SJAG_03558","SJAG_05344","SJAG_01809","SJAG_04474","SJAG_01508","SJAG_03726","SJAG_00284","SJAG_03907","SJAG_04517","SJAG_04609","SJAG_00104","SJAG_04644","SJAG_01167","SJAG_02177","SJAG_00379","SJAG_04391","SJAG_00800","SJAG_02805","SJAG_04002","SJAG_00192","SJAG_00108","SJAG_04931","SJAG_04565","SJAG_02482","SJAG_05345"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[79511,114778,62966,114989],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0030121"},{"annotations":[58827,80144,76346,110309],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0030122"},{"annotations":[113484,96130,98081,80044],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0030123"},{"annotations":[64716],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0030131"},{"annotations":[59234,66770],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0030130"},{"annotations":[78745],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0071439"},{"annotations":[75716,81656],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0030125"},{"annotations":[79903,80213,100400,65472,72758,95174,75527,81770,109094],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0030126"},{"annotations":[80335,74896,78985,73237,77082,78414,97461,77525,76728,73359],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0030127"}]},"cv_name":"cellular_component","definition":"Any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes, and possibly others. They are found associated with membranes on many vesicles as well as other membrane features such as pits and perhaps tubules.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"membrane protein complex","termid":"GO:0098796"},{"relation_name":"part_of","term_name":"cytoplasm","termid":"GO:0005737"},{"relation_name":"part_of","term_name":"coated membrane","termid":"GO:0048475"}],"gene_count":35,"genes_by_uniquename":{"SJAG_00072":null,"SJAG_00104":null,"SJAG_00108":null,"SJAG_00192":null,"SJAG_00284":null,"SJAG_00379":null,"SJAG_00800":null,"SJAG_00906":null,"SJAG_01167":null,"SJAG_01508":null,"SJAG_01809":null,"SJAG_02177":null,"SJAG_02234":null,"SJAG_02282":null,"SJAG_02349":null,"SJAG_02453":null,"SJAG_02482":null,"SJAG_02539":null,"SJAG_02805":null,"SJAG_03153":null,"SJAG_03558":null,"SJAG_03726":null,"SJAG_03907":null,"SJAG_04002":null,"SJAG_04070":null,"SJAG_04391":null,"SJAG_04474":null,"SJAG_04517":null,"SJAG_04565":null,"SJAG_04569":null,"SJAG_04609":null,"SJAG_04644":null,"SJAG_04931":null,"SJAG_05344":null,"SJAG_05345":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005737","GO:0032991","GO:0005575"],"is_obsolete":false,"name":"membrane coat","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0030117","terms_by_termid":{"GO:0030121":null,"GO:0030122":null,"GO:0030123":null,"GO:0030125":null,"GO:0030126":null,"GO:0030127":null,"GO:0030130":null,"GO:0030131":null,"GO:0071439":null}}


id: PBO:0000556
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADPH-dependent diflavin oxidoreductase, involved in iron-sulphur cluster assembly Tah18 (predicted)","termid":"PBO:0000556"}


id: GO:0035305
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a molecule.","definition_xrefs":["GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of dephosphorylation","termid":"GO:0035303"},{"relation_name":"is_a","term_name":"negative regulation of phosphate metabolic process","termid":"GO:0045936"},{"relation_name":"negatively_regulates","term_name":"dephosphorylation","termid":"GO:0016311"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of dephosphorylation","synonyms":[{"name":"down regulation of dephosphorylation","type":"exact"},{"name":"down-regulation of dephosphorylation","type":"exact"},{"name":"downregulation of dephosphorylation","type":"exact"},{"name":"inhibition of dephosphorylation","type":"narrow"}],"termid":"GO:0035305"}


id: PBO:0034359
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-in_syngeny_relationship_with","termid":"PBO:0034359"}


id: PBO:0062940
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"prolyl 4-hydroxylase subunit beta","termid":"PBO:0062940"}


id: GO:0002561
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a basophil.","definition_xrefs":["GOC:add","ISBN:0781735149"],"direct_ancestors":[{"relation_name":"is_a","term_name":"leukocyte degranulation","termid":"GO:0043299"},{"relation_name":"part_of","term_name":"basophil activation involved in immune response","termid":"GO:0002276"},{"relation_name":"part_of","term_name":"basophil mediated immunity","termid":"GO:0002560"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016192"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0008150","GO:0051179","GO:0016192"],"is_obsolete":false,"name":"basophil degranulation","termid":"GO:0002561"}


id: GO:1905005
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation.","definition_xrefs":["GOC:rl","GOC:BHF","GOC:TermGenie","PMID:18718461","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cardiac epithelial to mesenchymal transition","termid":"GO:0062042"},{"relation_name":"regulates","term_name":"epithelial to mesenchymal transition involved in endocardial cushion formation","termid":"GO:0003198"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of epithelial to mesenchymal transition involved in endocardial cushion formation","termid":"GO:1905005"}


id: PBO:0034289
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-in_plerology_relationship_with","termid":"PBO:0034289"}


id: PBO:0042673
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CEA cell adhesion molecule pseudogene 7","termid":"PBO:0042673"}


id: MONDO:0033954
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Mast cell activation syndrome where KIT-mutated and clonal mast cells are detected.","definition_xrefs":["PMID:23409940"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"mast cell activation syndrome","termid":"MONDO:0100004"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0005046"],"is_obsolete":false,"name":"monoclonal mast cell activation syndrome","secondary_identifiers":["MEDGEN:1672509","GARD:12980","NCIT:C181652","ICD10CM:D89.41","Orphanet:529468","UMLS:C4267893"],"synonyms":[{"name":"primary MCAS","type":"exact"},{"name":"primary mast cell activation syndrome","type":"exact"}],"termid":"MONDO:0033954","xrefs":{"Monarch":{"xref_id":"0033954"}}}


id: PBO:0078517
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tripartite motif containing 8","termid":"PBO:0078517"}


id: PBO:0070817
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L12 pseudogene 47","termid":"PBO:0070817"}


id: GO:0043255
data:
  {"annotated_genes":["SJAG_04659","SJAG_00424","SJAG_02278","SJAG_00963","SJAG_01787","SJAG_04462","SJAG_04668","SJAG_04771","SJAG_00610","SJAG_04509","SJAG_03705","SJAG_01255","SJAG_01376","SJAG_04666"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[80901,78982],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0045719"},{"annotations":[94368,89457],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140748"},{"annotations":[89841],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0032951"},{"annotations":[92717,69566,94352,107880,107309,119910,120043],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0090334"},{"annotations":[91386,94374,104802,96891],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070610"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of carbohydrate metabolic process","termid":"GO:0006109"},{"relation_name":"is_a","term_name":"regulation of biosynthetic process","termid":"GO:0009889"},{"relation_name":"regulates","term_name":"carbohydrate biosynthetic process","termid":"GO:0016051"}],"gene_count":14,"genes_by_uniquename":{"SJAG_00424":null,"SJAG_00610":null,"SJAG_00963":null,"SJAG_01255":null,"SJAG_01376":null,"SJAG_01787":null,"SJAG_02278":null,"SJAG_03705":null,"SJAG_04462":null,"SJAG_04509":null,"SJAG_04659":null,"SJAG_04666":null,"SJAG_04668":null,"SJAG_04771":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0005975","GO:0008150"],"is_obsolete":false,"name":"regulation of carbohydrate biosynthetic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null,"GO_REF:0000117":null},"synonyms":[{"name":"regulation of carbohydrate anabolism","type":"exact"},{"name":"regulation of carbohydrate biosynthesis","type":"exact"},{"name":"regulation of carbohydrate formation","type":"exact"},{"name":"regulation of carbohydrate synthesis","type":"exact"}],"termid":"GO:0043255","terms_by_termid":{"GO:0032951":null,"GO:0045719":null,"GO:0070610":null,"GO:0090334":null,"GO:0140748":null}}


id: SO:0001361
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"Five_methoxycarbonylmethyl_2_prime_O_methyluridine is a modified uridine base feature.","direct_ancestors":[{"relation_name":"is_a","term_name":"modified_uridine","termid":"SO:0001277"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"five_methoxycarbonylmethyl_two_prime_O_methyluridine","secondary_identifiers":["RNAMOD:069"],"synonyms":[{"name":"5-methoxycarbonylmethyl-2'-O-methyluridine","type":"exact"},{"name":"five methoxycarbonylmethyl two prime O methyluridine","type":"exact"},{"name":"mcm5Um","type":"exact"}],"termid":"SO:0001361"}


id: PBO:0084351
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Large subunit of trehalose 6-phosphate synthase/phosphatase complex; Tps1p-Tps2p complex converts uridine-5'-diphosphoglucose and glucose 6-phosphate to trehalose; contributes to survival to acute lethal heat stress; mutant has aneuploidy tolerance; protein abundance increases in response to DNA replication stress; TSL1 has a paralog, TPS3, that arose from the whole genome duplication","termid":"PBO:0084351"}


id: PBO:0075654
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"splA/ryanodine receptor domain and SOCS box containing 3","termid":"PBO:0075654"}


id: PBO:0076217
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Sad1 and UNC84 domain containing 5","termid":"PBO:0076217"}


id: PBO:0121007
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PDCD2 pseudogene 2","termid":"PBO:0121007"}


id: PBO:0075358
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sosondowah ankyrin repeat domain family member D","termid":"PBO:0075358"}


id: GO:0071401
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triglyceride stimulus.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to triglyceride","termid":"GO:0034014"},{"relation_name":"is_a","term_name":"cellular response to lipid","termid":"GO:0071396"},{"relation_name":"is_a","term_name":"cellular response to oxygen-containing compound","termid":"GO:1901701"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to triglyceride","synonyms":[{"name":"cellular response to triacylglyceride","type":"exact"},{"name":"cellular response to triacylglycerol","type":"exact"}],"termid":"GO:0071401"}


id: GO:0098545
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process in which a protein complex is maintained in a specific location within the cytoplasm and is prevented from moving elsewhere.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"maintenance of location in cell","termid":"GO:0051651"},{"relation_name":"is_a","term_name":"maintenance of protein complex location","termid":"GO:0098544"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0008150","GO:0051179"],"is_obsolete":false,"name":"maintenance of protein complex location in cytoplasm","termid":"GO:0098545"}


id: PBO:0075428
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sperm associated antigen 17","termid":"PBO:0075428"}


id: GO:0075514
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Viral-induced lysis of the endosome involved in uptake of a virus into a host cell. Occurs after internalization of the virus through the endosomal pathway, and results in release of the viral contents from the endosome into the host cell cytoplasm.","definition_xrefs":["GOC:bf","GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lysis of host organelle involved in viral entry into host cell","termid":"GO:0039664"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"endosome lysis involved in viral entry into host cell","synonyms":[{"name":"viral entry into host cell via caveolae-mediated endocytosis followed by endosome lysis","type":"exact"}],"termid":"GO:0075514"}


id: PATO:0001278
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A color consisting of orange hue and low saturation.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"orange","termid":"PATO:0000953"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"desaturated orange","synonyms":[{"name":"pale orange","type":"exact"}],"termid":"PATO:0001278"}


id: PBO:0067619
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 791, pseudogene","termid":"PBO:0067619"}


id: PBO:0028167
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_crossover_junction_endodeoxyribonuclease_activity","termid":"PBO:0028167"}


id: SO:0002244
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A transcript which is partially duplicated due to duplication of DNA, leading to a new transcript that is only partial and likely nonfunctional.","direct_ancestors":[{"relation_name":"is_a","term_name":"transcript_variant","termid":"SO:0001576"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"partially_duplicated_transcript","synonyms":[{"name":"partially duplicated transcript","type":"exact"}],"termid":"SO:0002244"}


id: PBO:0047281
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FA complementation group E","termid":"PBO:0047281"}


id: PBO:0030508
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_topoisomerase_inhibitor","termid":"PBO:0030508"}


id: MONDO:0000647
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A non-metastasizing neoplasm that arises from the vagina. Representative examples include squamous papilloma and melanocytic nevus.","definition_xrefs":["NCIT:C3610"],"direct_ancestors":[{"relation_name":"is_a","term_name":"benign female reproductive system neoplasm","termid":"MONDO:0000624"},{"relation_name":"is_a","term_name":"vaginal neoplasm","termid":"MONDO:0021050"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"benign vaginal neoplasm","secondary_identifiers":["SCTID:92473001","UMLS:C0154002","MEDGEN:57810","ICD10CM:D28.1","DOID:0060114","ICD9:221.1"],"synonyms":[{"name":"benign neoplasm of the vagina","type":"exact"},{"name":"benign neoplasm of vagina","type":"exact"},{"name":"benign tumor of the vagina","type":"exact"},{"name":"benign tumor of vagina","type":"exact"},{"name":"benign tumour of the vagina","type":"exact"},{"name":"benign tumour of vagina","type":"exact"},{"name":"benign vaginal neoplasm","type":"exact"},{"name":"benign vaginal neoplasms","type":"exact"},{"name":"benign vaginal tumor","type":"exact"},{"name":"benign vaginal tumour","type":"exact"},{"name":"vagina benign neoplasm","type":"exact"},{"name":"vagina female reproductive organ benign neoplasm","type":"exact"},{"name":"vaginal benign neoplasm","type":"exact"}],"termid":"MONDO:0000647","xrefs":{"Monarch":{"xref_id":"0000647"}}}


id: GO:0042785
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any mechanism of active immune avoidance which works by regulating host cytokine networks, e.g. by secreting proteins that mimic cytokine receptors that act to sequester host cytokines and inhibit action. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["PMID:9600978","PMID:9275219","PMID:10620615"],"gene_count":0,"genotype_count":0,"name":"obsolete evasion of host immune response via modulation of host cytokine network (obsolete GO:0042785)","synonyms":[{"name":"active evasion of host immune response via regulation of host cytokine network","type":"related"},{"name":"active evasion of immune response of other organism via regulation of cytokine network of other organism involved in symbiotic interaction","type":"broad"},{"name":"active immune evasion via modulation of host cytokine network","type":"exact"},{"name":"active immune evasion via regulation of host cytokine network","type":"exact"},{"name":"evasion of host immune response via regulation of host cytokine network","type":"exact"}],"termid":"GO:0042785"}


id: GO:1903699
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of a tarsal gland over time, from its formation to the mature structure.","definition_xrefs":["PMID:20664693","GO_REF:0000094","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sebaceous gland development","termid":"GO:0048733"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"tarsal gland development","synonyms":[{"name":"Meibomian gland development","type":"exact"},{"name":"gland of Meibom development","type":"exact"},{"name":"glandula tarsales development","type":"exact"},{"name":"tarsoconjunctival gland development","type":"related"}],"termid":"GO:1903699"}


id: SO:0000744
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"DNA belonging to the genome of a chromoplast, a colored plastid for synthesis and storage of pigments.","direct_ancestors":[{"relation_name":"is_a","term_name":"plastid_sequence","termid":"SO:0000740"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromoplast_sequence","synonyms":[{"name":"chromoplast sequence","type":"exact"}],"termid":"SO:0000744"}


id: PBO:0077078
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TIR domain containing adaptor molecule 1","termid":"PBO:0077078"}


id: MONDO:0016244
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare, genetic thrombotic microangiopathy due to dysregulation of the alternative complement pathway and characterized by the triad of hemolytic anemia, thrombocytopenia, and acute renal dysfunction.","definition_xrefs":["Orphanet:2134"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"hemolytic anemia","termid":"MONDO:0003664"},{"relation_name":"excluded_subClassOf","term_name":"kidney disorder","termid":"MONDO:0005240"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"complement deficiency","termid":"MONDO:0003832"},{"relation_name":"is_a","term_name":"thrombotic microangiopathy","termid":"MONDO:0019737"},{"relation_name":"is_a","term_name":"hereditary hemolytic uremic syndrome","termid":"MONDO:0957097"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005570"],"is_obsolete":false,"name":"atypical hemolytic-uremic syndrome","secondary_identifiers":["UMLS:C2931788","NANDO:1200474","NANDO:1200473","GARD:8702","NANDO:2200131","DOID:0080301","NCIT:C123223","MESH:D065766","MEDGEN:444141","NANDO:2200641","NORD:822"],"synonyms":[{"name":"Atypical Hemolytic Uremic Syndrome","type":"exact"},{"name":"D-HUS","type":"exact"},{"name":"D-minus hemolytic uremic syndrome (D-HUS)","type":"related"},{"name":"HUS, atypical","type":"related"},{"name":"aHUS","type":"exact"},{"name":"atypical HUS","type":"exact"},{"name":"atypical hemolytic uremic syndrome","type":"exact"},{"name":"hemolytic-uremic syndrome without diarrhea","type":"exact"},{"name":"hemolytic-uremic syndrome without diarrhoea","type":"exact"},{"name":"non-diarrhea-associated hemolytic uremic syndrome","type":"exact"}],"termid":"MONDO:0016244","xrefs":{"Monarch":{"xref_id":"0016244"}}}


id: PBO:0030029
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_adenylyl_cyclase_activity","termid":"PBO:0030029"}


id: PBO:0062385
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 7 subfamily E member 4 pseudogene","termid":"PBO:0062385"}


id: PBO:0042156
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"C-C motif chemokine ligand 17","termid":"PBO:0042156"}


id: PBO:0120993
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MYO9A antisense RNA 1","termid":"PBO:0120993"}


id: GO:0098508
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The generation of hematopoietic stem cells from hemogenic endothelial cells by a process that includes tight-junction dissolution and loss of cell polarity followed by delamination from the endothelium.","definition_xrefs":["PMID:22521721","PMID:20154732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell morphogenesis","termid":"GO:0000902"},{"relation_name":"is_a","term_name":"delamination","termid":"GO:0060232"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0007155"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0007155"}],"interesting_parent_ids":["GO:0007155","GO:0008150"],"is_obsolete":false,"name":"endothelial to hematopoietic transition","termid":"GO:0098508"}


id: PBO:0075202
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nuclear ribonucleoprotein polypeptide G pseudogene 14","termid":"PBO:0075202"}


id: MONDO:0016657
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"8p11.2 deletion syndrome is a contiguous gene syndrome characterized by the association of congenital spherocytosis, dysmorphic features, growth delay and hypogonadotropic hypogonadism.","definition_xrefs":["Orphanet:251066"],"direct_ancestors":[{"relation_name":"is_a","term_name":"partial deletion of the short arm of chromosome 8","termid":"MONDO:0016890"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"8p11.2 deletion syndrome","secondary_identifiers":["GARD:20693","MEDGEN:930174","SCTID:719646006","UMLS:C4304505"],"synonyms":[{"name":"Del(8)(p11.2)","type":"exact"},{"name":"monosomy 8p11.2","type":"exact"}],"termid":"MONDO:0016657","xrefs":{"Monarch":{"xref_id":"0016657"}}}


id: PBO:0001011
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PXA domain protein Pxa1","termid":"PBO:0001011"}


id: GO:1904889
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of excitatory synapse assembly.","definition_xrefs":["GO_REF:0000058","GOC:bf","GOC:PARL","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of synapse assembly","termid":"GO:0051963"},{"relation_name":"regulates","term_name":"excitatory synapse assembly","termid":"GO:1904861"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0008150","GO:0044085"],"is_obsolete":false,"name":"regulation of excitatory synapse assembly","synonyms":[{"name":"regulation of excitatory synapse formation","type":"exact"}],"termid":"GO:1904889"}


id: SO:0002167
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"IsomiRs are all the bona fide variants of a mature product. IsomiRs should be connected to the ref_miRNA it is most likely to be the variant of. Some isomiRs can be variations of one or multiple ref_miRNA.","definition_xrefs":["PMID:26453491"],"direct_ancestors":[{"relation_name":"is_a","term_name":"miRNA","termid":"SO:0000276"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"isomiR","termid":"SO:0002167"}


id: PBO:0001909
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"holo-[acyl-carrier-protein] synthase (predicted)","termid":"PBO:0001909"}


id: PR:O94662
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPBC651.04 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O94662"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C651.04 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC651.04","synonyms":[{"name":"Spom972h-SPBC651.04","type":"exact"}],"termid":"PR:O94662"}


id: PBO:0042536
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CDK5 regulatory subunit associated protein 3","termid":"PBO:0042536"}


id: PR:Q09094
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- rec15 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q09094"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiotic recombination protein rec15 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC1711.14","synonyms":[{"name":"Spom972h-rec15","type":"exact"}],"termid":"PR:Q09094"}


id: MOD:00782
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-leucine residue to N-acetyl-L-leucine.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified L-leucine residue","termid":"MOD:00911"},{"relation_name":"is_a","term_name":"alpha-amino acetylated residue","termid":"MOD:01458"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00408"}],"interesting_parent_ids":["MOD:00408"],"is_obsolete":false,"name":"N-acetyl-L-leucine","synonyms":[{"name":"AcLeu","type":"exact"}],"termid":"MOD:00782"}


id: MONDO:0010615
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"isolated congenital growth hormone deficiency","termid":"MONDO:0000050"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320"],"is_obsolete":false,"name":"isolated growth hormone deficiency type III","secondary_identifiers":["SCTID:234533006","OMIM:307200","UMLS:C0472813","Orphanet:231692","DOID:0060875","MEDGEN:141630","GARD:3921","MESH:C537149"],"synonyms":[{"name":"Fleisher syndrome","type":"exact"},{"name":"Growth hormone deficiency with hypogammaglobulinemia","type":"related"},{"name":"IGHD 3","type":"related"},{"name":"IGHD III","type":"exact"},{"name":"IGHD3","type":"related"},{"name":"X-linked IGHD","type":"exact"},{"name":"X-linked agammaglobulinemia and isolated growth hormone deficiency","type":"exact"},{"name":"X-linked hypogammaglobulinemia and isolated growth hormone deficiency","type":"exact"},{"name":"X-linked isolated growth hormone deficiency","type":"exact"},{"name":"agammaglobulinemia and isolated Growth hormone deficiency, X-linked","type":"related"},{"name":"congenital IGHD type III","type":"exact"},{"name":"congenital isolated GH deficiency type III","type":"exact"},{"name":"congenital isolated growth hormone deficiency type III","type":"exact"},{"name":"growth hormone deficiency with hypogammaglobulinemia","type":"exact"},{"name":"hypogammaglobulinemia and isolated Growth hormone deficiency, X-linked","type":"related"},{"name":"isolated growth hormone deficiency type 3","type":"related"},{"name":"isolated growth hormone deficiency type III","type":"exact"},{"name":"isolated growth hormone deficiency, type 3","type":"related"},{"name":"isolated growth hormone deficiency, type III","type":"related"},{"name":"isolated growth hormone deficiency, type IIi, with agammaglobulinemia, X-linked recessive","type":"exact"}],"termid":"MONDO:0010615","xrefs":{"Monarch":{"xref_id":"0010615"}}}


id: MONDO:0012275
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Fetal valproate syndrome (FVS), is an anticonvulsant drug-related embryofetopathy that can occur when a fetus is exposed to valproic acid (VPA), characterized by distinct facial dysmorphism, congenital anomalies and developmental delay (especially in language and communication).","definition_xrefs":["Orphanet:1906"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"toxic or drug-related embryofetopathy","termid":"MONDO:0016677"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fetal valproate syndrome","secondary_identifiers":["UMLS:C0236026","MedDRA:10016524","NORD:1141","SCTID:17231009","MEDGEN:65922","GARD:5447","icd11.foundation:1055155432","ICD9:759.89","DOID:0060471","MESH:C536525","NCIT:C98930","OMIM:609442"],"synonyms":[{"name":"FVS","type":"related"},{"name":"fetal valproate syndrome","type":"exact"},{"name":"fetal valproic acid syndrome","type":"exact"},{"name":"foetal valproic acid syndrome","type":"exact"},{"name":"susceptibility to valproate embryopathy","type":"related"},{"name":"valproate embryopathy, susceptibility to","type":"related"},{"name":"valproic acid embryopathy","type":"related"}],"termid":"MONDO:0012275","xrefs":{"Monarch":{"xref_id":"0012275"}}}


id: PBO:0065401
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proteasome 20S subunit alpha 4","termid":"PBO:0065401"}


id: PBO:0035831
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_histone_H4_acetylation_during_vegetative_growth","termid":"PBO:0035831"}


id: GO:0070131
data:
  {"annotated_genes":["SJAG_03550","SJAG_01249","SJAG_01517"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[100656,114669],"is_not":false,"summary":null,"term":"GO:0070131"},{"annotations":[102420],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070134"}]},"cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of translation","termid":"GO:0045727"},{"relation_name":"is_a","term_name":"regulation of mitochondrial translation","termid":"GO:0070129"},{"relation_name":"positively_regulates","term_name":"mitochondrial translation","termid":"GO:0032543"}],"gene_count":3,"genes_by_uniquename":{"SJAG_01249":null,"SJAG_01517":null,"SJAG_03550":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0140053"},{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467","GO:0140053"],"is_obsolete":false,"name":"positive regulation of mitochondrial translation","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"positive regulation of mitochondrial protein anabolism","type":"exact"},{"name":"positive regulation of mitochondrial protein biosynthesis","type":"exact"},{"name":"positive regulation of mitochondrial protein formation","type":"exact"},{"name":"positive regulation of mitochondrial protein synthesis","type":"exact"}],"termid":"GO:0070131","terms_by_termid":{"GO:0070131":null,"GO:0070134":null}}


id: MONDO:0014279
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete arrhythmogenic right ventricular dysplasia, familial, 13 (obsolete MONDO:0014279)","termid":"MONDO:0014279","xrefs":{"Monarch":{"xref_id":"0014279"}}}


id: GO:0060324
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure development","termid":"GO:0048856"},{"relation_name":"part_of","term_name":"head development","termid":"GO:0060322"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"face development","termid":"GO:0060324"}


id: PBO:0060743
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADH:ubiquinone oxidoreductase complex assembly factor 8","termid":"PBO:0060743"}


id: PBO:0075587
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine peptidase inhibitor Kazal type 14 (putative)","termid":"PBO:0075587"}


id: MONDO:0011742
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Hirschsprung disease, susceptibility to","termid":"MONDO:0100179"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Hirschsprung disease, susceptibility to, 7","secondary_identifiers":["UMLS:C1969836","MEDGEN:370761","OMIM:606875"],"synonyms":[{"name":"HSCR7","type":"exact"},{"name":"Hirschsprung disease, susceptibility to, 7","type":"exact"}],"termid":"MONDO:0011742","xrefs":{"Monarch":{"xref_id":"0011742"}}}


id: PBO:0056939
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MIR7-3 host gene","termid":"PBO:0056939"}


id: GO:0004047
data:
  {"annotated_genes":["SJAG_02901"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[58153],"is_not":false,"summary":null,"term":"GO:0004047"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[protein] + (6S)-5,6,7,8-tetrahydrofolate = N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NH4+.","definition_xrefs":["RHEA:16945"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydroxymethyl-, formyl- and related transferase activity","termid":"GO:0016742"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02901":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016741","GO:0016740"],"is_obsolete":false,"name":"aminomethyltransferase activity","references_by_uniquename":{"GO_REF:0000003":null},"secondary_identifiers":["MetaCyc:GCVT-RXN","EC:2.1.2.10","Reactome:R-HSA-5693977"],"synonyms":[{"name":"S-aminomethyldihydrolipoylprotein:(6S)-tetrahydrofolate aminomethyltransferase (ammonia-forming) activity","type":"related"},{"name":"T-protein","type":"related"},{"name":"glycine synthase activity","type":"related"},{"name":"glycine-cleavage system T-protein activity","type":"related"},{"name":"protein-8-S-aminomethyldihydrolipoyllysine:tetrahydrofolate aminomethyltransferase (ammonia-forming) activity","type":"related"},{"name":"protein-S8-aminomethyldihydrolipoyllysine:tetrahydrofolate aminomethyltransferase (ammonia-forming) activity","type":"related"},{"name":"tetrahydrofolate aminomethyltransferase activity","type":"related"}],"termid":"GO:0004047","terms_by_termid":{"GO:0004047":null}}


id: PBO:0071619
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L36a pseudogene 37","termid":"PBO:0071619"}


id: PBO:0081758
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 688","termid":"PBO:0081758"}


id: PBO:0061424
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NQO1 divergent transcript","termid":"PBO:0061424"}


id: MONDO:0011980
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"autoimmune thyroid disease, susceptibility to","termid":"MONDO:0000162"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"autoimmune thyroid disease, susceptibility to, 1","secondary_identifiers":["MEDGEN:334160","OMIM:608173","UMLS:C1842446"],"synonyms":[{"name":"AITD1","type":"related"},{"name":"autoimmune thyroid disease, susceptibility to, 1","type":"exact"},{"name":"autoimmune thyroid disease, susceptibility to, type 1","type":"exact"}],"termid":"MONDO:0011980","xrefs":{"Monarch":{"xref_id":"0011980"}}}


id: GO:0032244
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of nucleobase-containing compound transport","termid":"GO:0032241"},{"relation_name":"is_a","term_name":"regulation of nucleoside transport","termid":"GO:0032242"},{"relation_name":"positively_regulates","term_name":"nucleoside transport","termid":"GO:0015858"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0008150"],"is_obsolete":false,"name":"positive regulation of nucleoside transport","synonyms":[{"name":"activation of nucleoside transport","type":"narrow"},{"name":"stimulation of nucleoside transport","type":"narrow"},{"name":"up regulation of nucleoside transport","type":"exact"},{"name":"up-regulation of nucleoside transport","type":"exact"},{"name":"upregulation of nucleoside transport","type":"exact"}],"termid":"GO:0032244"}


id: MONDO:0800111
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Persistent tachypnoe of infancy that presents with with no other airway or parenchymal abnormalities upon scanning (N=80; 63%).","definition_xrefs":["PMID:26474448","PMID:32761949"],"direct_ancestors":[{"relation_name":"is_a","term_name":"persistent tachypnoe of infancy","termid":"MONDO:0800109"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"persistent tachypnoe of infancy, usual","synonyms":[{"name":"PTI, usual","type":"exact"}],"termid":"MONDO:0800111","xrefs":{"Monarch":{"xref_id":"0800111"}}}


id: SO:0000059
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A binding site that, of a nucleotide molecule, that interacts selectively and non-covalently with polypeptide residues of a nuclease.","definition_xrefs":["SO:cb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleotide_to_protein_binding_site","termid":"SO:0001654"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nuclease_binding_site","synonyms":[{"name":"nuclease binding site","type":"exact"}],"termid":"SO:0000059"}


id: PBO:0005539
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiotic recombination protein Rec7","termid":"PBO:0005539"}


id: PBO:0013079
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"does not functionally complement E. coli hisD","termid":"PBO:0013079"}


id: FYPO:0002288
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of tyrosine residues in one or more specific proteins, or of specific protein sites, does not occur.","definition_xrefs":["PomBase:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete abolished protein tyrosine phosphorylation during vegetative growth (obsolete FYPO:0002288)","synonyms":[{"name":"abolished peptidyl-tyrosine phosphorylation during vegetative growth","type":"exact"},{"name":"abolished protein tyrosine phosphorylation during mitotic cell cycle","type":"related"},{"name":"protein tyrosine phosphorylation abolished during vegetative growth","type":"exact"}],"termid":"FYPO:0002288"}


id: PBO:0029154
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_cumene_hydroperoxide","termid":"PBO:0029154"}


id: GO:1900313
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of maltohexaose transport.","definition_xrefs":["GOC:mengo_curators","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of hexasaccharide transport","termid":"GO:1900298"},{"relation_name":"is_a","term_name":"regulation of maltohexaose transport","termid":"GO:1900312"},{"relation_name":"negatively_regulates","term_name":"maltohexaose transport","termid":"GO:2001103"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"negatively_regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0006810"],"is_obsolete":false,"name":"negative regulation of maltohexaose transport","synonyms":[{"name":"down regulation of maltohexaose transport","type":"exact"},{"name":"down-regulation of maltohexaose transport","type":"exact"},{"name":"downregulation of maltohexaose transport","type":"exact"},{"name":"inhibition of maltohexaose transport","type":"narrow"}],"termid":"GO:1900313"}


id: PR:Q09739
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A meiotic nuclear division protein 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO00227","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiotic coiled-coil protein 7 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC13A11.03","secondary_identifiers":["UniProtKB:Q09739"],"synonyms":[{"name":"Spom972h-MND1","type":"exact"},{"name":"meiotically up-regulated gene 32 protein (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q09739"}


id: PBO:0046436
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"esophagus epithelial intergenic associated transcript","termid":"PBO:0046436"}


id: PBO:0083179
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the dubious ORF YHR180W-A","termid":"PBO:0083179"}


id: GO:0043230
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi.","definition_xrefs":["PMID:9914479","GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"organelle","termid":"GO:0043226"},{"relation_name":"part_of","term_name":"extracellular region","termid":"GO:0005576"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005576"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0005576"],"is_obsolete":false,"name":"extracellular organelle","termid":"GO:0043230"}


id: PBO:0086158
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein required for proper cell fusion and cell morphology; forms a complex with Bud14p and Kel2p that regulates Bnr1p (formin) to affect actin cable assembly, cytokinesis, and polarized growth; functions in a complex with Kel2p to negatively regulate mitotic exit, interacts with Tem1p and Lte1p; localizes to regions of polarized growth; potential Cdc28p substrate","termid":"PBO:0086158"}


id: PBO:0041871
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"calcium sensing receptor","termid":"PBO:0041871"}


id: PBO:0002754
data:
  {"annotation_feature_type":"gene","cv_name":"gene_ex","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcriptionally induced by Mat1-Mc","termid":"PBO:0002754"}


id: PBO:0032765
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase Erg26 (predicted)","termid":"PBO:0032765"}


id: FYPO:0009042
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of sorbitol than normal.","definition_xrefs":["PomBase:mlr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased resistance to chemical during vegetative growth","termid":"FYPO:0000126"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002682"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0000139"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0002682","FYPO:0005447","FYPO:0000003","FYPO:0000139"],"is_obsolete":false,"name":"resistance to sorbitol","synonyms":[{"name":"resistance to sorbitol during mitotic cell cycle","type":"related"},{"name":"resistance to sorbitol during vegetative growth","type":"exact"},{"name":"resistant to sorbitol","type":"exact"}],"termid":"FYPO:0009042"}


id: GO:0033743
data:
  {"annotated_genes":["SJAG_00365"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[78911],"is_not":false,"summary":null,"term":"GO:0033743"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: peptide-L-methionine + H2O + thioredoxin disulfide = peptide-L-methionine (R)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the R enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin.","definition_xrefs":["GOC:vw","GOC:mah","EC:1.8.4.12","RHEA:24164"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor","termid":"GO:0016671"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00365":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"peptide-methionine (R)-S-oxide reductase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["KEGG_REACTION:R07607","MetaCyc:1.8.4.12-RXN","GO:0000318","Reactome:R-HSA-5676917"],"synonyms":[{"name":"MsrB","type":"related"},{"name":"PilB","type":"related"},{"name":"SelR","type":"related"},{"name":"SelX","type":"related"},{"name":"methionine S-oxide reductase (R-form oxidizing) activity","type":"related"},{"name":"methionine S-oxide reductase activity","type":"broad"},{"name":"methionine sulfoxide reductase B activity","type":"narrow"},{"name":"methionine sulfoxide reductase activity","type":"broad"},{"name":"pMRsr","type":"related"},{"name":"pMSR","type":"related"},{"name":"peptide-methionine:thioredoxin-disulfide S-oxidoreductase [methionine (R)-S-oxide-forming] activity","type":"related"},{"name":"protein-methionine-R-oxide reductase activity","type":"exact"},{"name":"selenoprotein R","type":"related"}],"termid":"GO:0033743","terms_by_termid":{"GO:0033743":null}}


id: PBO:0059135
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MPHOSPH10 pseudogene 2","termid":"PBO:0059135"}


id: GO:0040006
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Attaching of a protein-based cuticle to the epithelium underlying it.","definition_xrefs":["GOC:mtg_sensu","GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete protein-based cuticle attachment to epithelium (obsolete GO:0040006)","synonyms":[{"name":"cuticular attachment to epithelium","type":"broad"},{"name":"protein-based cuticle attachment to epithelium","type":"exact"}],"termid":"GO:0040006"}


id: MONDO:0957301
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"spermatogenic failure","termid":"MONDO:0004983"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005047"}],"interesting_parent_ids":["MONDO:0005047"],"is_obsolete":false,"name":"spermatogenic failure 84","secondary_identifiers":["OMIM:620409","UMLS:C5830562","MEDGEN:1841198","DOID:0070583"],"termid":"MONDO:0957301","xrefs":{"Monarch":{"xref_id":"0957301"}}}


id: PBO:0064897
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein phosphatase 2 regulatory subunit B'gamma","termid":"PBO:0064897"}


id: MOD:02039
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces a hydrogen group with a amino group","direct_ancestors":[{"relation_name":"is_a","term_name":"protein modification categorized by chemical process","termid":"MOD:01156"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aminated residue","synonyms":[{"name":"AmRes","type":"exact"}],"termid":"MOD:02039"}


id: GO:0060462
data:
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id: GO:0098827
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id: GO:0140767
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id: GO:0045209
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id: PBO:0075983
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id: GO:0018302
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id: PBO:0087870
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id: PBO:0051875
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id: GO:0102784
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id: MONDO:0006800
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A form of apraxia characterized by an acquired inability to carry out a complex motor activity despite the ability to mentally formulate the action. This condition has been attributed to a disruption of connections between the dominant parietal cortex and supplementary and premotor cortical regions in both hemispheres. (From Adams et al., Principles of Neurology, 6th ed, p57)","definition_xrefs":["MESH:D020240"],"direct_ancestors":[{"relation_name":"is_a","term_name":"apraxia","termid":"MONDO:0000665"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ideomotor apraxia","secondary_identifiers":["SCTID:229706001","UMLS:C0234523","DOID:4627","EFO:1000980","ICD9:315.8","MedDRA:10021216","MEDGEN:115961"],"synonyms":[{"name":"classic apraxia","type":"exact"},{"name":"classic apraxia (finding) [ambiguous]","type":"exact"},{"name":"ideomotor dyspraxia","type":"exact"},{"name":"limb-kinetic apraxia","type":"exact"},{"name":"limb-kinetic apraxia (finding)","type":"exact"},{"name":"transcortical apraxia","type":"exact"},{"name":"transcortical apraxia (finding)","type":"exact"}],"termid":"MONDO:0006800","xrefs":{"Monarch":{"xref_id":"0006800"}}}


id: MONDO:0001731
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A non-metastasizing neoplasm that arises from the vagina and is characterized by the presence of benign epithelial and benign mesenchymal elements.","definition_xrefs":["NCIT:C40275"],"direct_ancestors":[{"relation_name":"is_a","term_name":"benign vaginal neoplasm","termid":"MONDO:0000647"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"benign vaginal mixed epithelial and mesenchymal neoplasm","secondary_identifiers":["MEDGEN:267349","UMLS:C1511106","DOID:135"],"synonyms":[{"name":"benign vaginal carcinosarcoma","type":"related"},{"name":"benign vaginal mixed epithelial and mesenchymal neoplasm","type":"exact"},{"name":"benign vaginal mixed epithelial and mesenchymal tumor","type":"exact"},{"name":"benign vaginal mixed epithelial and mesenchymal tumour","type":"exact"}],"termid":"MONDO:0001731","xrefs":{"Monarch":{"xref_id":"0001731"}}}


id: GO:0019528
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of D-arabitol to form D-xylulose 5-phosphate. D-arabitol is converted into D-xylulose, which is then phosphorylated to form D-xylulose-5-phosphate.","definition_xrefs":["MetaCyc:DARABITOLUTIL-PWY"],"direct_ancestors":[{"relation_name":"is_a","term_name":"D-arabitol catabolic process","termid":"GO:0051159"},{"relation_name":"is_a","term_name":"D-xylulose 5-phosphate metabolic process","termid":"GO:0051167"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0044281","GO:0005975","GO:0008150"],"is_obsolete":false,"name":"D-arabitol catabolic process to D-xylulose 5-phosphate","synonyms":[{"name":"D-arabitol breakdown to xylulose 5-phosphate","type":"exact"},{"name":"D-arabitol degradation","type":"related"},{"name":"D-arabitol degradation to xylulose 5-phosphate","type":"exact"},{"name":"D-arabitol utilization","type":"related"}],"termid":"GO:0019528"}


id: PBO:0067538
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 683, pseudogene","termid":"PBO:0067538"}


id: PBO:0071940
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S4X pseudogene 17","termid":"PBO:0071940"}


id: MONDO:0013325
data:
  {"annotated_genes":["SJAG_02211"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88976],"is_not":false,"summary":null,"term":"MONDO:0013325"}]},"cv_name":"mondo","definition":"COG5-CDG is an extremely rare form of CDG syndrome characterized clinically in the single reported case to date by moderate mental retardation with slow and inarticulate speech, truncal ataxia, and mild hypotonia.","definition_xrefs":["Orphanet:263487"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"congenital disorder of glycosylation type II","termid":"MONDO:0005501"},{"relation_name":"is_a","term_name":"defect in conserved oligomeric Golgi complex","termid":"MONDO:0017750"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02211":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0024322"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0024322"],"is_obsolete":false,"name":"COG5-congenital disorder of glycosylation","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["SCTID:721100009","UMLS:C3150876","OMIM:613612","DOID:0070261","MEDGEN:462226","GARD:12348"],"synonyms":[{"name":"CDG III","type":"related"},{"name":"CDG syndrome type 3","type":"related"},{"name":"CDG syndrome type III","type":"exact"},{"name":"CDG-III","type":"exact"},{"name":"CDG2I","type":"exact"},{"name":"COG5-CDG","type":"exact"},{"name":"COG5-CDG (CDG-III)","type":"related"},{"name":"COG5-congenital disorder of glycosylation","type":"exact"},{"name":"carbohydrate deficient glycoprotein syndrome type III","type":"exact"},{"name":"congenital disorder of glycosylation type 2i","type":"exact"},{"name":"congenital disorder of glycosylation type III","type":"exact"},{"name":"congenital disorder of glycosylation, type III","type":"related"}],"termid":"MONDO:0013325","terms_by_termid":{"MONDO:0013325":null},"xrefs":{"Monarch":{"xref_id":"0013325"}}}


id: FYPO:0005336
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of histone H3 measured in the cell is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal cellular histone level","termid":"FYPO:0004981"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001312","FYPO:0001320","FYPO:0000257","FYPO:0000002"],"is_obsolete":false,"name":"normal level of histone H3 in cell","synonyms":[{"name":"normal accumulation of histone H3 in cell","type":"related"},{"name":"normal cellular histone H3 level","type":"exact"},{"name":"normal histone H3 level during vegetative growth","type":"exact"},{"name":"normal level of histone H3 in cell during mitotic cell cycle","type":"related"},{"name":"normal level of histone H3 in cell during vegetative growth","type":"exact"}],"termid":"FYPO:0005336"}


id: GO:0006837
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monoamine transport","termid":"GO:0015844"},{"relation_name":"is_a","term_name":"organic hydroxy compound transport","termid":"GO:0015850"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0008150","GO:0051179","GO:0006810"],"is_obsolete":false,"name":"serotonin transport","termid":"GO:0006837"}


id: MONDO:0015760
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A non-Hodgkin lymphoma of T-cell lineage. It includes the T lymphoblastic lymphoma and the mature T- and NK-cell lymphomas. -- 2003","definition_xrefs":["NCIT:C3466"],"direct_ancestors":[{"relation_name":"is_a","term_name":"non-Hodgkin lymphoma","termid":"MONDO:0018908"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"T-cell non-Hodgkin lymphoma","secondary_identifiers":["MedDRA:10042971","DOID:0081312","ICD9:202.70","MESH:D016399","SCTID:109978004","UMLS:C0079772","GARD:20133","Orphanet:171918","MEDGEN:86957"],"synonyms":[{"name":"T cell lymphoma","type":"exact"},{"name":"T-cell NHL","type":"exact"},{"name":"T-cell and NK-cell non-Hodgkin lymphoma","type":"exact"},{"name":"T-cell and NK-cell non-Hodgkin's lymphoma","type":"exact"},{"name":"T-cell lymphoma","type":"exact"},{"name":"T-cell non-Hodgkin lymphoma","type":"exact"},{"name":"T-cell non-Hodgkin's lymphoma","type":"exact"},{"name":"non-Hodgkin's T-cell lymphoma","type":"exact"}],"termid":"MONDO:0015760","xrefs":{"Monarch":{"xref_id":"0015760"}}}


id: GO:0099005
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The component of the postsynaptic recycling endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.","definition_xrefs":["GOC:autophagy","GOC:mf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"extrinsic component of postsynaptic endosome membrane","termid":"GO:0098999"},{"relation_name":"part_of","term_name":"postsynaptic recycling endosome membrane","termid":"GO:0098944"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0031410"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005768"}],"interesting_parent_ids":["GO:0005737","GO:0031410","GO:0005575","GO:0005768"],"is_obsolete":false,"name":"extrinsic component of postsynaptic recycling endosome membrane","termid":"GO:0099005"}


id: PBO:0051804
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"IQ motif and Sec7 domain ArfGEF 3","termid":"PBO:0051804"}


id: PBO:0111800
data:
  {"annotation_feature_type":"gene","cv_name":"pombase_family_or_domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Req family helicase","termid":"PBO:0111800"}


id: GO:0005497
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to an androgen, a male sex hormone.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hormone binding","termid":"GO:0042562"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005488","GO:0003674"],"is_obsolete":false,"name":"androgen binding","termid":"GO:0005497"}


id: PBO:0075373
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SRY-box transcription factor 10","termid":"PBO:0075373"}


id: GO:0008308
data:
  {"annotated_genes":["SJAG_00048"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[73575],"is_not":false,"summary":null,"term":"GO:0008308"}]},"cv_name":"molecular_function","definition":"Enables the transmembrane transfer of an anion by a voltage-gated channel. An anion is a negatively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.","definition_xrefs":["GOC:vw","GOC:mtg_transport","ISBN:0815340729"],"direct_ancestors":[{"relation_name":"is_a","term_name":"voltage-gated monoatomic ion channel activity","termid":"GO:0005244"},{"relation_name":"is_a","term_name":"monoatomic anion channel activity","termid":"GO:0005253"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00048":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0022857","GO:0005215","GO:0003674"],"is_obsolete":false,"name":"voltage-gated monoatomic anion channel activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["Reactome:R-HSA-9012374","GO:0022844"],"synonyms":[{"name":"voltage-dependent ion-selective channel activity","type":"related"},{"name":"voltage-gated anion channel activity","type":"broad"},{"name":"voltage-gated ion-selective channel activity","type":"related"}],"termid":"GO:0008308","terms_by_termid":{"GO:0008308":null}}


id: MONDO:0005427
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete vasuclar dementia (obsolete MONDO:0005427)","termid":"MONDO:0005427","xrefs":{"Monarch":{"xref_id":"0005427"}}}


id: PBO:0034461
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_protein_localization_to_cell_periphery","termid":"PBO:0034461"}


id: GO:0009475
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete high-molecular-weight cytochrome c (hexadecaheme) (obsolete GO:0009475)","synonyms":[{"name":"high-molecular-weight cytochrome c (hexadecaheme)","type":"exact"}],"termid":"GO:0009475"}


id: MONDO:0008209
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Char syndrome is characterized by the triad of patent ductus arteriosus (PDA), facial dysmorphism and hand anomalies.","definition_xrefs":["Orphanet:46627"],"direct_ancestors":[{"relation_name":"is_a","term_name":"patent ductus arteriosus","termid":"MONDO:0011827"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-variable intellectual disability syndrome","termid":"MONDO:0015160"},{"relation_name":"is_a","term_name":"syndromic congenital heart disease","termid":"MONDO:0100614"},{"relation_name":"is_a","term_name":"TFAP2B-related congenital heart disease spectrum disorder","termid":"MONDO:1010098"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"Char syndrome","secondary_identifiers":["SCTID:703534001","GARD:1237","DOID:0060563","UMLS:C1868570","ICD9:759.89","MEDGEN:358356","MESH:C566815","OMIM:169100"],"synonyms":[{"name":"CHAR","type":"related"},{"name":"CHAR syndrome","type":"related"},{"name":"Char","type":"related"},{"name":"Char syndrome","type":"exact"},{"name":"patent ductus arteriosus with Facial Dysmorphism and abnormal fifth digits","type":"related"},{"name":"patent ductus arteriosus with facial dysmorphism and abnormal fifth digits","type":"exact"}],"termid":"MONDO:0008209","xrefs":{"Monarch":{"xref_id":"0008209"}}}


id: PBO:0028503
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-unequal_mitotic_sister_chromatid_segregation","termid":"PBO:0028503"}


id: MONDO:0005872
data:
  {"annotated_genes":["SJAG_05313","SJAG_04755","SJAG_03677","SJAG_01895","SJAG_01671","SJAG_00260"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[89114],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014937"},{"annotations":[88965],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011121"},{"annotations":[87548],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007273"},{"annotations":[87755],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013602"},{"annotations":[89273,89274],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013224"}]},"cv_name":"mondo","definition":"A primary or metastatic malignant neoplasm involving the nervous system.","definition_xrefs":["NCIT:C4788"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cancer","termid":"MONDO:0004992"},{"relation_name":"is_a","term_name":"nervous system neoplasm","termid":"MONDO:0021248"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00260":null,"SJAG_01671":null,"SJAG_01895":null,"SJAG_03677":null,"SJAG_04755":null,"SJAG_05313":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"nervous system cancer","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:99231","ICD9:192.8","MESH:D009423","DOID:3093","ICD9:192.9","EFO:0007392","ICD9:192","UMLS:C0497549","SCTID:372063002"],"synonyms":[{"name":"nervous system neoplasms, malignant","type":"exact"},{"name":"neural neoplasm","type":"broad"},{"name":"neural tumor","type":"broad"},{"name":"neural tumour","type":"broad"},{"name":"tumor of the nervous system","type":"broad"},{"name":"tumour of the nervous system","type":"broad"},{"name":"cancer of nervous system","type":"exact"},{"name":"malignant neoplasm of nervous system","type":"exact"},{"name":"malignant neoplasm of the nervous system","type":"exact"},{"name":"malignant nervous system neoplasm","type":"exact"},{"name":"malignant nervous system tumor","type":"exact"},{"name":"malignant nervous system tumour","type":"exact"},{"name":"malignant tumor of nervous system","type":"exact"},{"name":"malignant tumor of the nervous system","type":"exact"},{"name":"malignant tumour of nervous system","type":"exact"},{"name":"malignant tumour of the nervous system","type":"exact"},{"name":"nervous system cancer","type":"exact"},{"name":"nervous system neoplasm","type":"broad"}],"termid":"MONDO:0005872","terms_by_termid":{"MONDO:0007273":null,"MONDO:0011121":null,"MONDO:0013224":null,"MONDO:0013602":null,"MONDO:0014937":null},"xrefs":{"Monarch":{"xref_id":"0005872"}}}


id: GO:0008051
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. A complex that possesses farnesyl-diphosphate farnesyl transferase activity.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete farnesyl-diphosphate farnesyl transferase complex (obsolete GO:0008051)","synonyms":[{"name":"farnesyl-diphosphate farnesyl transferase complex","type":"exact"}],"termid":"GO:0008051"}


id: MOD:01990
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts a glycine residue to a glycinium (protonated glycine).","definition_xrefs":["ChEBI:64723","PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified glycine residue","termid":"MOD:00908"},{"relation_name":"is_a","term_name":"alpha-amino protonated residue","termid":"MOD:01700"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protonated glycine (glycinium) residue","termid":"MOD:01990"}


id: GO:1901198
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any positive regulation of calcium ion transport into cytosol that is involved in cellular response to calcium ion.","definition_xrefs":["GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of calcium ion transport into cytosol","termid":"GO:0010524"},{"relation_name":"part_of","term_name":"cellular response to calcium ion","termid":"GO:0071277"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0055085"},{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0055085","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"positive regulation of calcium ion transport into cytosol involved in cellular response to calcium ion","synonyms":[{"name":"positive regulation of calcium ion transport into cytosol involved in cellular response to Ca2+ ion","type":"exact"}],"termid":"GO:1901198"}


id: GO:0033168
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process in which double-stranded siRNA molecules are converted to single-stranded siRNAs; required for the formation of a mature RITS complex during RNA interference.","definition_xrefs":["GOC:mah","PMID:17310250"],"gene_count":0,"genotype_count":0,"name":"obsolete conversion of ds siRNA to ss siRNA involved in RNA interference (obsolete GO:0033168)","synonyms":[{"name":"RNA interference, conversion of ds siRNA to ss siRNA","type":"exact"}],"termid":"GO:0033168"}


id: MONDO:0011476
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Immunodeficiency by defective expression of HLA class 1 is a very rare, primary, genetic, immunodeficiency disorder characterized by partial or complete absence of human leukocyte antigen class I expression resulting in a non-specific clinical picture of impaired immune response and susceptibility to infections.","definition_xrefs":["Orphanet:34592"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"severe combined immunodeficiency","termid":"MONDO:0015974"},{"relation_name":"excluded_subClassOf","term_name":"non-SCID combined immunodeficiency","termid":"MONDO:0018814"},{"relation_name":"is_a","term_name":"combined immunodeficiency","termid":"MONDO:0015131"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"MHC class I deficiency","secondary_identifiers":["icd11.foundation:489749747","SCTID:725136003","DOID:0060009","MEDGEN:346868","NANDO:1200328","GARD:8427","OMIMPS:604571","UMLS:C1858266","NANDO:2200701"],"synonyms":[{"name":"BARE lymphocyte syndrome, type I","type":"related"},{"name":"BLS type 1","type":"related"},{"name":"BLS, type I","type":"exact"},{"name":"BLSI","type":"exact"},{"name":"Bare lymphocyte syndrome type 1","type":"exact"},{"name":"Bare lymphocyte syndrome, type 1","type":"related"},{"name":"Bls, type 1","type":"related"},{"name":"HLA CLASS I deficiency","type":"exact"},{"name":"HLA Class 1 deficiency","type":"related"},{"name":"bare lymphocyte syndrome type I","type":"exact"},{"name":"immunodeficiency by defective expression of HLA class 1","type":"exact"},{"name":"immunodeficiency by defective expression of HLA class type 1","type":"exact"}],"termid":"MONDO:0011476","xrefs":{"Monarch":{"xref_id":"0011476"}}}


id: PBO:0053345
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 226","termid":"PBO:0053345"}


id: PBO:0061541
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NSUN5 pseudogene 1","termid":"PBO:0061541"}


id: GO:0002234
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of events in which a stimulus generated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum is received and converted into a molecular signal.","definition_xrefs":["PMID:10390516","GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ER overload response","termid":"GO:0006983"},{"relation_name":"is_a","term_name":"detection of biotic stimulus","termid":"GO:0009595"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"detection of endoplasmic reticulum overloading","synonyms":[{"name":"detection of ER overloading","type":"exact"}],"termid":"GO:0002234"}


id: PBO:0016984
data:
  {"annotation_feature_type":"gene","cv_name":"misc","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rer2 can form a catalytically active complex with S. cerevisiae Nus1p","termid":"PBO:0016984"}


id: GO:0010047
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process leading to the spontaneous opening of the fruit permitting the escape of seeds.","definition_xrefs":["ISBN:0471245208","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dehiscence","termid":"GO:0009900"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"fruit dehiscence","termid":"GO:0010047"}


id: PBO:0039639
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aldehyde oxidase 2, pseudogene","termid":"PBO:0039639"}


id: GO:0017063
data:
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id: MONDO:0015190
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id: PBO:0085404
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id: PBO:0049346
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id: MONDO:0009920
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  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Acro-oto-ocular syndrome is a very rare disorder associating pseudopapilledema (optic disk swelling not secondary to increased intracranial pressure), mixed hearing loss, facial dysmorphism and limb extremity anomalies.","definition_xrefs":["Orphanet:2980"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Acrootoocular syndrome","secondary_identifiers":["MESH:C564866","SCTID:720410001","UMLS:C1849661","GARD:4559","MEDGEN:337882","OMIM:264475"],"synonyms":[{"name":"Aoo syndrome","type":"related"},{"name":"acrootoocular syndrome","type":"exact"},{"name":"pseudopapilledema, ocular hypotelorism, blepharophimosis, and hand anomalies","type":"related"},{"name":"pseudopapilledema-blepharophimosis-hand anomalies syndrome","type":"exact"}],"termid":"MONDO:0009920","xrefs":{"Monarch":{"xref_id":"0009920"}}}


id: MONDO:0043529
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  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Cardiac manifestation of gastrointestinal CARCINOID TUMOR that metastasizes to the liver. Substances secreted by the tumor cells, including SEROTONIN, promote fibrous plaque formation in ENDOCARDIUM and its underlying layers. These deposits cause distortion of the TRICUSPID VALVE and the PULMONARY VALVE eventually leading to STENOSIS and valve regurgitation.","definition_xrefs":["MESH:D002275"],"direct_ancestors":[{"relation_name":"is_a","term_name":"heart disorder","termid":"MONDO:0005267"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"carcinoid heart disease","secondary_identifiers":["SCTID:36222008","MEDGEN:762","UMLS:C0007093"],"synonyms":[{"name":"carcinoid heart disease","type":"exact"},{"name":"carcinoid heart diseases","type":"related"},{"name":"heart disease, carcinoid","type":"related"},{"name":"heart diseases, carcinoid","type":"related"}],"termid":"MONDO:0043529","xrefs":{"Monarch":{"xref_id":"0043529"}}}


id: GO:0042749
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id: MONDO:0002231
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id: PBO:0075004
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id: MONDO:0010656
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  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An X-linked dominant condition caused by mutation(s) in the IQSEC2 gene, encoding IQ motif and SEC7 domain-containing protein 2. It is characterized by substantially impaired intellectual functioning and behavioral abnormalities.","definition_xrefs":["NCIT:C133729"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"X-linked syndromic intellectual disability","termid":"MONDO:0020119"},{"relation_name":"is_a","term_name":"non-syndromic X-linked intellectual disability","termid":"MONDO:0019181"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"intellectual disability, X-linked 1","secondary_identifiers":["GARD:22699","MESH:C567906","MEDGEN:444070","UMLS:C2931498","Orphanet:397933","DOID:0112038","OMIM:309530","MESH:C564489"],"synonyms":[{"name":"IQSEC2","type":"related"},{"name":"IQSEC2-related disorder","type":"exact"},{"name":"IQSEC2-related epilepsy","type":"related"},{"name":"IQSEC2-related intellectual disability","type":"related"},{"name":"IQSEC2-related syndromic intellectual disability","type":"exact"},{"name":"MRX","type":"exact"},{"name":"MRX1","type":"exact"},{"name":"MRX78","type":"exact"},{"name":"X-linked intellectual disability 1","type":"related"},{"name":"X-linked intellectual disability 1/78","type":"related"},{"name":"X-linked intellectual disability 78","type":"related"},{"name":"intellectual developmental disorder, X-linked 1, X-linked dominant","type":"exact"},{"name":"intellectual disability, X-linked 1","type":"exact"},{"name":"mental retardation, X-linked 1","type":"exact"},{"name":"mental retardation, X-linked 18","type":"exact"},{"name":"mental retardation, X-linked 78","type":"exact"},{"name":"mental retardation, X-linked type 1","type":"exact"},{"name":"severe intellectual disability-progressive postnatal microcephaly-midline stereotypic hand movements syndrome","type":"related"}],"termid":"MONDO:0010656","xrefs":{"Monarch":{"xref_id":"0010656"}}}


id: PBO:0090670
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial CH-OH group oxidoreductase, human RTN4IP1 ortholog, implicated in mitochondrial organization or tethering","termid":"PBO:0090670"}


id: PBO:0061810
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id: PR:O94307
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  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A prefoldin subunit 5 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO03960"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"prefoldin subunit 5 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC215.02","secondary_identifiers":["UniProtKB:O94307"],"synonyms":[{"name":"Spom972h-PFDN5","type":"exact"},{"name":"byr1-binding protein Bob1 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O94307"}


id: GO:0097217
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  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A pit-like area in the cell wall of a sieve element; contains pores lined with callose and occupied by strands of protoplasmic material that interconnect the protoplasts of contiguous sieve elements.","definition_xrefs":["POC:curators","ISBN:0471738433"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"plant-type cell wall","termid":"GO:0009505"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005618"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005618","GO:0005575"],"is_obsolete":false,"name":"sieve area","termid":"GO:0097217"}


id: GO:0006069
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id: PBO:0080444
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id: MONDO:1010998
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  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Syringomyelia that occurs in dog.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syringomyelia, non-human animal","termid":"MONDO:1010236"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"syringomyelia, dog","secondary_identifiers":["OMIA:000965-9615"],"termid":"MONDO:1010998","xrefs":{"Monarch":{"xref_id":"1010998"}}}


id: GO:0090522
data:
  {"annotated_genes":["SJAG_02166","SJAG_03938","SJAG_01925","SJAG_03864","SJAG_03357","SJAG_02320","SJAG_04044","SJAG_04960"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[60906,67482,90571,92693,101502,103879,116155,119732],"is_not":false,"summary":null,"term":"GO:0090522"}]},"cv_name":"biological_process","definition":"The initial, indirect interaction between a secretory vesicle membrane and a site of exocytosis in the plasma membrane. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to docking and fusion.","definition_xrefs":["PMID:17488620","PMID:22420621","PMID:10559876","GOC:rn","PMID:27243008","PMID:17052174"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vesicle tethering","termid":"GO:0099022"},{"relation_name":"is_a","term_name":"exocytic process","termid":"GO:0140029"}],"gene_count":8,"genes_by_uniquename":{"SJAG_01925":null,"SJAG_02166":null,"SJAG_02320":null,"SJAG_03357":null,"SJAG_03864":null,"SJAG_03938":null,"SJAG_04044":null,"SJAG_04960":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0016192"}],"interesting_parent_ids":["GO:0016192","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"vesicle tethering involved in exocytosis","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000107":null},"synonyms":[{"name":"vesicle tethering to plasma membrane","type":"narrow"}],"termid":"GO:0090522","terms_by_termid":{"GO:0090522":null}}


id: GO:0042722
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The change in morphology and behavior of alpha-beta T cells resulting from exposure to a superantigen, a microbial antigen with an extremely potent activating effect on T cells that bear a specific variable region.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"alpha-beta T cell activation","termid":"GO:0046631"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"alpha-beta T cell activation by superantigen","synonyms":[{"name":"alpha-beta T lymphocyte activation by superantigen","type":"exact"},{"name":"alpha-beta T-cell activation by superantigen","type":"exact"},{"name":"alpha-beta T-lymphocyte activation by superantigen","type":"exact"}],"termid":"GO:0042722"}


id: FYPO:0005733
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of glutamate-ammonia ligase activity is increased during a cellular response to iron ion starvation.","definition_xrefs":["PMID:20435771","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased glutamate-ammonia ligase activity","termid":"FYPO:0002270"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000661"}],"interesting_parent_ids":["FYPO:0000661","FYPO:0000654","FYPO:0000652","FYPO:0000707","FYPO:0001985"],"is_obsolete":false,"name":"increased glutamate-ammonia ligase activity during cellular response to iron ion starvation","synonyms":[{"name":"increased GS activity during cellular response to iron ion starvation","type":"exact"},{"name":"increased glutamate-ammonia ligase activity during iron ion starvation","type":"exact"},{"name":"increased glutamine synthetase activity during cellular response to iron ion starvation","type":"exact"},{"name":"increased glutamylhydroxamic synthetase activity during cellular response to iron ion starvation","type":"exact"}],"termid":"FYPO:0005733"}


id: GO:0008250
data:
  {"annotated_genes":["SJAG_04090","SJAG_05348","SJAG_04127","SJAG_01006","SJAG_01389","SJAG_03333","SJAG_01069"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[64322,66126,76316,77232,80759,81129,101987],"is_not":false,"summary":null,"term":"GO:0008250"}]},"cv_name":"cellular_component","definition":"A protein complex that is found in the endoplasmic reticulum membrane of eukaryotes and transfers lipid-linked oligosaccharide precursor to asparagine residues on nascent proteins. The complex includes at least eight non-identical subunits. Different forms of the complex containing distinct subunits have been detected in mammals.","definition_xrefs":["PMID:15835887","PMID:31810196","PMID:32316603"],"direct_ancestors":[{"relation_name":"is_a","term_name":"membrane protein complex","termid":"GO:0098796"},{"relation_name":"is_a","term_name":"endoplasmic reticulum protein-containing complex","termid":"GO:0140534"},{"relation_name":"is_a","term_name":"transferase complex","termid":"GO:1990234"},{"relation_name":"part_of","term_name":"endoplasmic reticulum membrane","termid":"GO:0005789"}],"gene_count":7,"genes_by_uniquename":{"SJAG_01006":null,"SJAG_01069":null,"SJAG_01389":null,"SJAG_03333":null,"SJAG_04090":null,"SJAG_04127":null,"SJAG_05348":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005783"},{"rel_name":"part_of","termid":"GO:0005789"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0032991","GO:0005575","GO:0005737","GO:0005783","GO:0005789"],"is_obsolete":false,"name":"oligosaccharyltransferase complex","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null,"GO_REF:0000117":null},"synonyms":[{"name":"OST complex","type":"exact"},{"name":"OSTCI","type":"narrow"},{"name":"OSTCII","type":"narrow"},{"name":"OSTCIII","type":"narrow"},{"name":"oligosaccharyl transferase complex","type":"exact"}],"termid":"GO:0008250","terms_by_termid":{"GO:0008250":null}}


id: GO:0015534
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: (proline, glycine or betaine)(out) + (H+ or Na+)(out) = (proline, glycine or betaine)(in) + (H+ or Na+)(in).","definition_xrefs":["TC:2.A.1.6.4"],"gene_count":0,"genotype_count":0,"name":"obsolete proline/glycine/betaine:hydrogen/sodium symporter activity (obsolete GO:0015534)","synonyms":[{"name":"proline/glycine/betaine:hydrogen/sodium symporter activity","type":"exact"},{"name":"proline/glycine/betaine:proton/sodium symporter","type":"exact"}],"termid":"GO:0015534"}


id: PBO:0040638
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BASP1 antisense RNA 1","termid":"PBO:0040638"}


id: GO:0038037
data:
  {"annotated_genes":["SJAG_01978"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[72602],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0038038"}]},"cv_name":"cellular_component","definition":"A protein complex that contains two G protein-coupled receptors.","definition_xrefs":["GOC:al","GOC:bf","PMID:10713101"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G protein-coupled receptor complex","termid":"GO:0097648"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01978":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005886"}],"interesting_parent_ids":["GO:0005886","GO:0005575","GO:0032991"],"is_obsolete":false,"name":"G protein-coupled receptor dimeric complex","references_by_uniquename":{"GO_REF:0000033":null},"synonyms":[{"name":"G-protein coupled receptor dimer","type":"exact"},{"name":"G-protein coupled receptor dimeric complex","type":"exact"},{"name":"GPCR dimer","type":"exact"}],"termid":"GO:0038037","terms_by_termid":{"GO:0038038":null}}


id: GO:0070817
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process in which the P-TEFb-cap methyltransferase complex is transported to, or maintained in, a specific location.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex localization","termid":"GO:0031503"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0051179","GO:0008150"],"is_obsolete":false,"name":"P-TEFb-cap methyltransferase complex localization","synonyms":[{"name":"P-TEFb-cap methyltransferase complex localisation","type":"exact"},{"name":"establishment and maintenance of P-TEFb-cap methyltransferase complex localization","type":"exact"}],"termid":"GO:0070817"}


id: FYPO:0003247
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which occurrence of histone H3 binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal histone binding","termid":"FYPO:0007157"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000702"},{"rel_name":"is_a","termid":"FYPO:0000652"}],"interesting_parent_ids":["FYPO:0000652","FYPO:0000707","FYPO:0001985","FYPO:0000702"],"is_obsolete":false,"name":"abolished histone H3 binding","synonyms":[{"name":"abolished protein-histone H3 interaction","type":"exact"},{"name":"histone H3 binding abolished","type":"exact"}],"termid":"FYPO:0003247"}


id: PBO:0091891
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA translocase/ubiquitin protein ligase E3, human ERCC4 ortholog Rhp16/Rad16","termid":"PBO:0091891"}


id: PBO:0070126
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U7 small nuclear 40 pseudogene","termid":"PBO:0070126"}


id: PBO:0027657
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_protein_phosphorylation_during_cellular_response_to_hydroxyurea","termid":"PBO:0027657"}


id: PBO:0002758
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"conserved fungal protein, with meiosis specific splicing","termid":"PBO:0002758"}


id: PBO:0059112
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"motile sperm domain containing 1","termid":"PBO:0059112"}


id: GO:0001699
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The regulated release of gastric acid by parietal cells in response to acetylcholine.","definition_xrefs":["GOC:hjd"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gastric acid secretion","termid":"GO:0001696"},{"relation_name":"part_of","term_name":"cellular response to acetylcholine","termid":"GO:1905145"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0051179","GO:0006810"],"is_obsolete":false,"name":"acetylcholine-induced gastric acid secretion","termid":"GO:0001699"}


id: PBO:0036263
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial dihydroorotate dehydrogenase Ura3","termid":"PBO:0036263"}


id: FYPO:0001272
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which mitotic sister chromatid segregation stops before completing separation of chromosomes, and DNA becomes spread into an indistinct mass along much of the length of the mitotic spindle.","definition_xrefs":["PomBase:mah","PMID:22711988"],"direct_ancestors":[{"relation_name":"is_a","term_name":"incomplete, unequal mitotic sister chromatid segregation","termid":"FYPO:0001271"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"part_of","termid":"FYPO:0000337"},{"rel_name":"part_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"part_of","termid":"FYPO:0001320"},{"rel_name":"part_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000641"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"part_of","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000337"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0005447","FYPO:0000641","FYPO:0000631","FYPO:0001320","FYPO:0001985","FYPO:0000337"],"is_obsolete":false,"name":"incomplete, unequal mitotic sister chromatid segregation, with smeared DNA","synonyms":[{"name":"incomplete, unequal mitotic sister chromatid segregation, with smeared DNA during vegetative growth","type":"exact"},{"name":"incomplete, unequal mitotic sister chromatid separation, with smeared DNA","type":"related"},{"name":"incomplete, unequal sister chromatid segregation, with smeared DNA during mitotic cell cycle","type":"related"}],"termid":"FYPO:0001272"}


id: PBO:0016619
data:
  {"annotation_feature_type":"gene","cv_name":"feature_cvtermprop_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"quant_gene_ex_copies_per_cell","termid":"PBO:0016619"}


id: _global:involved_in_regulation_of
data:
  {"annotation_feature_type":"gene","cv_name":"external","definition":"c involved in regulation of p if c is involved in some p' and p' regulates some p","direct_ancestors":[{"relation_name":"is_a","term_name":"acts_upstream_of","termid":"_global:acts_upstream_of"},{"relation_name":"is_a","term_name":"involved_in_or_involved_in_regulation_of","termid":"_global:involved_in_or_involved_in_regulation_of"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"involved_in_regulation_of","secondary_identifiers":["RO:0002428"],"termid":"_global:involved_in_regulation_of"}


id: MONDO:0015821
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Mycosis fungoides (MF) and its variants represent the most common forms of cutaneous T-cell lymphomas. The term MF is restricted to the classical form characterized by the slow progression of patches, plaques and tumors, and to variants with a similar indolent course.","definition_xrefs":["Orphanet:178566"],"direct_ancestors":[{"relation_name":"is_a","term_name":"indolent primary cutaneous T-cell lymphoma","termid":"MONDO:0015816"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005093"},{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0005093","MONDO:0004992"],"is_obsolete":false,"name":"mycosis fungoides and variants","secondary_identifiers":["icd11.foundation:2036068731","GARD:20166"],"termid":"MONDO:0015821","xrefs":{"Monarch":{"xref_id":"0015821"}}}


id: PBO:0087760
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of THO/TREX complexes; this complex couple transcription elongation with mitotic recombination and with mRNA metabolism and export, subunit of an RNA Pol II complex; regulates lifespan; involved in telomere maintenance; similar to Top1p","termid":"PBO:0087760"}


id: MONDO:0004419
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"infiltrating bladder urothelial carcinoma","termid":"MONDO:0003890"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"lymphoma-like variant infiltrating bladder urothelial carcinoma","secondary_identifiers":["NCIT:C39822","DOID:7972"],"synonyms":[{"name":"infiltrating bladder urothelial carcinoma, lymphoma-like variant","type":"exact"}],"termid":"MONDO:0004419","xrefs":{"Monarch":{"xref_id":"0004419"}}}


id: PBO:0036227
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_histone_H3-K4_methylation_at_telomere_during_vegetative_growth","termid":"PBO:0036227"}


id: PBO:0091521
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mcs4-Associated Kinase","termid":"PBO:0091521"}


id: MONDO:0017027
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete primary interstitial lung disease specific to adulthood (obsolete MONDO:0017027)","secondary_identifiers":["Orphanet:264740"],"synonyms":[{"name":"primary ILD specific to adulthood","type":"exact"}],"termid":"MONDO:0017027","xrefs":{"Monarch":{"xref_id":"0017027"}}}


id: MONDO:0018503
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"gastric carcinoma","termid":"MONDO:0004950"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0004992"],"is_obsolete":false,"name":"carcinoma of stomach, salivary gland type","secondary_identifiers":["Orphanet:423781"],"synonyms":[{"name":"gastric carcinoma, salivary gland type","type":"exact"}],"termid":"MONDO:0018503","xrefs":{"Monarch":{"xref_id":"0018503"}}}


id: PBO:0068153
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 460","termid":"PBO:0068153"}


id: FYPO:0006372
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which homologous chromosomes or sister chromatids do not separate completely during meiosis I or meiosis II, and partially separated DNA masses are connected by one or more bridges formed of chromatin.","definition_xrefs":["PomBase:mah","PMID:29123917"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal meiotic chromosome segregation","termid":"FYPO:0000151"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"part_of","termid":"FYPO:0005447"},{"rel_name":"part_of","termid":"FYPO:0001985"},{"rel_name":"part_of","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000631","FYPO:0005447","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"incomplete meiotic chromosome segregation, with chromosomal bridge","synonyms":[{"name":"abnormal meiotic chromosome segregation, with chromosomal bridge","type":"exact"},{"name":"incomplete chromosome segregation, with chromosomal bridge, during meiosis","type":"exact"},{"name":"incomplete meiotic chromosome segregation, with chromatin bridge","type":"exact"}],"termid":"FYPO:0006372"}


id: PBO:0082132
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Actin-binding protein of the cortical actin cytoskeleton; important for activation of actin nucleation mediated by the Arp2/Arp3 complex; inhibits actin filament elongation at the barbed-end; phosphorylation within its proline-rich region, mediated by Cdc28p and Pho85p, protects Abp1p from PEST sequence-mediated proteolysis; mammalian homolog of HIP-55 (hematopoietic progenitor kinase 1 [HPK1]-interacting protein of 55 kDa)","termid":"PBO:0082132"}


id: PBO:0113235
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Nitrogen-responsive activator of Start; nuclear microprotein with transcriptional activator activity; bypasses Start arrest in a cln3 bck2 double mutant when overexpressed; interacts with subunits of the SBF complex (Swi4p-Swi6p); induced by nitrogen limitation and rapamycin with peak abundance at Start; proposed to promote the G1/S transition by rewiring the G1/S transcriptional machinery under poor nitrogen conditions upstream of the Whi5-inhibited form of SBF and independent of Cln3 and Bck2","termid":"PBO:0113235"}


id: MOD:02016
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-lysine residue to N6-arachidonoyl-L-lysine.","direct_ancestors":[{"relation_name":"is_a","term_name":"N6-acylated L-lysine","termid":"MOD:01875"},{"relation_name":"is_a","term_name":"N-arachidonoylated residue","termid":"MOD:02017"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:01155"},{"rel_name":"is_a","termid":"MOD:01875"}],"interesting_parent_ids":["MOD:01875","MOD:01155"],"is_obsolete":false,"name":"N6-arachidonoyl-L-lysine","termid":"MOD:02016"}


id: PBO:0087631
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of the DSC ubiquitin ligase complex; protein of unknown function that localizes to the ER and vacuole lumen; overexpression affects endocytic protein trafficking; ortholog of fission yeast dsc3","termid":"PBO:0087631"}


id: PBO:0087304
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ski complex component and putative RNA helicase; mediates 3'-5' RNA degradation by the cytoplasmic exosome; null mutants have superkiller phenotype of increased viral dsRNAs and are synthetic lethal with mutations in 5'-3' mRNA decay; mutations in the human ortholog, SKIV2L, causes Syndromic diarrhea/Trichohepatoenteric (SD/THE) syndrome","termid":"PBO:0087304"}


id: MONDO:0005145
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Sporadic amyotrophic lateral sclerosis is a amyotrophic lateral sclerosis in which there is no known cause, such as no family history.","definition_xrefs":["EFO:0001357"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amyotrophic lateral sclerosis","termid":"MONDO:0004976"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"sporadic amyotrophic lateral sclerosis","secondary_identifiers":["DOID:0080917","UMLS:C1862941","MEDGEN:400171"],"termid":"MONDO:0005145","xrefs":{"Monarch":{"xref_id":"0005145"}}}


id: GO:0019883
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of endogenous origin on its cell surface in association with an MHC protein complex.","definition_xrefs":["GOC:add","ISBN:0781735149","PMID:15771591","PMID:15928678"],"direct_ancestors":[{"relation_name":"is_a","term_name":"antigen processing and presentation","termid":"GO:0019882"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"antigen processing and presentation of endogenous antigen","synonyms":[{"name":"antigen presentation, endogenous antigen","type":"exact"}],"termid":"GO:0019883"}


id: PBO:0086104
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein required for assembly of cytochrome c oxidase; exists as an oligomer; described as both an integral mitochondrial inner membrane protein facing the intermembrane space (IMS) and as a soluble IMS protein; contains a twin Cx9C motif; imported into the IMS via the MIA import machinery","termid":"PBO:0086104"}


id: GO:0008881
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-glutamate = D-glutamate.","definition_xrefs":["RHEA:12813","EC:5.1.1.3"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amino-acid racemase activity","termid":"GO:0047661"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016853"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016853","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"glutamate racemase activity","secondary_identifiers":["KEGG_REACTION:R00260","MetaCyc:GLUTRACE-RXN"],"termid":"GO:0008881"}


id: PBO:0081986
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger and SCAN domain containing 12 pseudogene 1","termid":"PBO:0081986"}


id: PBO:0066320
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ring-box 1","termid":"PBO:0066320"}


id: PBO:0044742
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DEAD-box helicase 20","termid":"PBO:0044742"}


id: PBO:0084242
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Initiator methionine 2'-O-ribosyl phosphate transferase; modifies the initiator methionine tRNA at position 64 to distinguish it from elongator methionine tRNA","termid":"PBO:0084242"}


id: PBO:0076995
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"THAP9 antisense RNA 1","termid":"PBO:0076995"}


id: _global:parasite_of
data:
  {"annotation_feature_type":"gene","cv_name":"external","direct_ancestors":[{"relation_name":"is_a","term_name":"go_annotation_extension_relation","termid":"_global:go_annotation_extension_relation"},{"relation_name":"is_a","term_name":"has_host","termid":"_global:has_host"},{"relation_name":"is_a","term_name":"interacts_with_via_parasite-host_interaction","termid":"_global:interacts_with_via_parasite-host_interaction"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"parasite_of","secondary_identifiers":["RO:0002444"],"synonyms":[{"name":"direct parasite of","type":"exact"}],"termid":"_global:parasite_of"}


id: PBO:0028805
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_genetic_imprinting_at_mating-type_locus","termid":"PBO:0028805"}


id: PBO:0031452
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_nuclear_pore_distribution","termid":"PBO:0031452"}


id: PBO:0064870
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein phosphatase 1 regulatory subunit 26 pseudogene 3","termid":"PBO:0064870"}


id: GO:0052926
data:
  {"annotated_genes":["SJAG_00334"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[63628],"is_not":false,"summary":null,"term":"GO:0052926"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H+.","definition_xrefs":["RHEA:29531"],"direct_ancestors":[{"relation_name":"is_a","term_name":"alpha-1,2-mannosyltransferase activity","termid":"GO:0000026"},{"relation_name":"is_a","term_name":"GlcNAc(2)-PP-Dol mannosyltransferase activity","termid":"GO:0120562"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00334":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016757"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016757","GO:0016740","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity","references_by_uniquename":{"GO_REF:0000003":null},"secondary_identifiers":["KEGG_REACTION:R06259","MetaCyc:RXN-5467","EC:2.4.1.259"],"synonyms":[{"name":"dolichylphosphomannose-dependent ALG9 mannosyltransferase activity","type":"related"}],"termid":"GO:0052926","terms_by_termid":{"GO:0052926":null}}


id: MONDO:0010531
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Contractures - ectodermal dysplasia - cleft lip/palate is an ectodermal dyplasia syndrome characterized by severe arthrogryposis, multiple ectodermal dysplasia features, cleft lip/palate, facial dysmorphism, growth deficiency and a moderate delay of psychomotor development. Ectodermal dysplasia manifestations include sparse, brittle and hypopigmented hair, xerosis, multiple nevi, small conical shaped teeth and hypodontia, and facial dysmorphism with blepharophimosis, deep-set eyes and micrognathia.","definition_xrefs":["Orphanet:1484"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"is_a","term_name":"ectodermal dysplasia syndrome","termid":"MONDO:0019287"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"contractures-ectodermal dysplasia-cleft lip/palate syndrome","secondary_identifiers":["UMLS:C1844935","OMIM:301815","MEDGEN:375546","GARD:1515","SCTID:720746006"],"synonyms":[{"name":"Ladda Zonana Ramer syndrome","type":"related"},{"name":"Ladda-Zonana-Ramer syndrome","type":"exact"},{"name":"arthrogryposis, ectodermal dysplasia, cleft LIP/palate, and developmental delay","type":"related"},{"name":"congenital contractures, ectodermal dysplasia, cleft lip/palate, and developmental impairment","type":"related"},{"name":"contractures ectodermal dysplasia cleft lip palate","type":"related"}],"termid":"MONDO:0010531","xrefs":{"Monarch":{"xref_id":"0010531"}}}


id: PBO:0085480
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Probable mitochondrial seryl-tRNA synthetase; mutant displays increased invasive and pseudohyphal growth","termid":"PBO:0085480"}


id: PBO:0047698
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FLYWCH-type zinc finger 1 pseudogene 1","termid":"PBO:0047698"}


id: PBO:0087799
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Synthase subunit of trehalose-6-P synthase/phosphatase complex; synthesizes the storage carbohydrate trehalose, which is critically important for survival of long-term desiccation; also found in a monomeric form; expression is induced by the stress response and repressed by the Ras-cAMP pathway; protein abundance increases in response to DNA replication stress and in response to prolonged exposure to boric acid","termid":"PBO:0087799"}


id: PATO:0001494
data:
  {"annotation_feature_type":"gene","cv_name":"quality","direct_ancestors":[{"relation_name":"is_a","term_name":"growth rate","termid":"PATO:0001492"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hypotrophic growth","termid":"PATO:0001494"}


id: PBO:0086587
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative protein of unknown function; epitope-tagged protein localizes to the cytoplasm; YHR033W has a paralog, PRO1, that arose from the whole genome duplication","termid":"PBO:0086587"}


id: MONDO:0010624
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete IFAP/BRESHECK syndrome (obsolete MONDO:0010624)","termid":"MONDO:0010624","xrefs":{"Monarch":{"xref_id":"0010624"}}}


id: GO:0051163
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"arabitol metabolic process","termid":"GO:0051161"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0008150","GO:0044281","GO:0005975"],"is_obsolete":false,"name":"D-arabitol metabolic process","synonyms":[{"name":"D-arabitol metabolism","type":"exact"}],"termid":"GO:0051163"}


id: PBO:0002719
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mannosyltransferase complex subunit, Anp family Mnn9 (predicted)","termid":"PBO:0002719"}


id: MOD:01701
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively removes a hydrogen cation, a proton, forming an anionic residue.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein modification categorized by chemical process","termid":"MOD:01156"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"deprotonated residue","synonyms":[{"name":"H-NRes","type":"exact"}],"termid":"MOD:01701"}


id: MONDO:0016807
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Pure mitochondrial myopathy is a rare mitochondrial disease characterized by exclusive skeletal muscle involvement, without clinical evidence of other organ involvement, manifesting with progressive limb weakness, proximal limb muscle atrophy, and eye muscle anomalies (e.g. ocular motility restriction, ptosis). Patients may present with lactic acidosis, diffuse myalgia and overall fatigability (particularly during/after physical activities), dysphagia, and diminished deep tendon reflexes.","definition_xrefs":["Orphanet:254854"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mitochondrial disease","termid":"MONDO:0044970"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pure mitochondrial myopathy","secondary_identifiers":["UMLS:C4517289","SCTID:732245008","GARD:20768","MEDGEN:1375079","icd11.foundation:141365898"],"termid":"MONDO:0016807","xrefs":{"Monarch":{"xref_id":"0016807"}}}


id: MONDO:0011193
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any cone dystrophy in which the cause of the disease is a mutation in the GUCA1A gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cone dystrophy","termid":"MONDO:0000455"},{"relation_name":"is_a","term_name":"cone-rod dystrophy","termid":"MONDO:0015993"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"cone dystrophy 3","secondary_identifiers":["UMLS:C1865869","OMIM:602093","DOID:0080314","GARD:15342","MEDGEN:356104"],"synonyms":[{"name":"COD3","type":"related"},{"name":"GUCA1A cone dystrophy","type":"exact"},{"name":"cone dystrophy 3","type":"exact"},{"name":"cone dystrophy caused by mutation in GUCA1A","type":"exact"},{"name":"cone dystrophy type 3","type":"exact"},{"name":"cone dystrophy-3","type":"exact"},{"name":"cone-rod dystrophy 14","type":"related"},{"name":"retinal cone dystrophy","type":"related"}],"termid":"MONDO:0011193","xrefs":{"Monarch":{"xref_id":"0011193"}}}


id: PBO:0050339
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heterogeneous nuclear ribonucleoprotein A1 pseudogene 41","termid":"PBO:0050339"}


id: PBO:0062770
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 52 subfamily X member 1 pseudogene","termid":"PBO:0062770"}


id: GO:1905107
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Dizocilpine stimulus.","definition_xrefs":["GO_REF:0000071","PMID:20064280","GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete cellular response to Dizocilpine (obsolete GO:1905107)","termid":"GO:1905107"}


id: GO:0032101
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of a response to an external stimulus.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of response to stimulus","termid":"GO:0048583"},{"relation_name":"regulates","term_name":"response to external stimulus","termid":"GO:0009605"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of response to external stimulus","termid":"GO:0032101"}


id: FYPO:0000350
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the actin cytoskeleton is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal cytoskeleton morphology during vegetative growth","termid":"FYPO:0000352"},{"relation_name":"is_a","term_name":"abnormal actin cytoskeleton during vegetative growth","termid":"FYPO:0002398"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0004803"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000002","FYPO:0004803","FYPO:0001985","FYPO:0001320"],"is_obsolete":false,"name":"abnormal actin cytoskeleton morphology during vegetative growth","synonyms":[{"name":"abnormal actin cytoskeleton morphology during mitotic cell cycle","type":"related"},{"name":"actin cytoskeleton morphology: abnormal","type":"related"}],"termid":"FYPO:0000350"}


id: PBO:0057649
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 1244-2","termid":"PBO:0057649"}


id: PBO:0055326
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2754","termid":"PBO:0055326"}


id: GO:0072256
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular mesangial cell.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glomerular mesangial cell fate commitment","termid":"GO:0072152"},{"relation_name":"part_of","term_name":"metanephric glomerular mesangial cell differentiation","termid":"GO:0072254"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"metanephric glomerular mesangial cell fate commitment","termid":"GO:0072256"}


id: PBO:0054398
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1794","termid":"PBO:0054398"}


id: MONDO:0005511
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Deficiency of janus kinase-3 causing the near absence of T lymphocytes and Natural killer cells; and normal or elevated B lymphocytes due to an autosomal recessive variant of severe combined immunodeficiency.","definition_xrefs":["EFO:0005565"],"direct_ancestors":[{"relation_name":"is_a","term_name":"severe combined immunodeficiency","termid":"MONDO:0015974"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"janus kinase-3 deficiency","secondary_identifiers":["DOID:0060008","Wikipedia:Janus_kinase_3_deficiency"],"termid":"MONDO:0005511","xrefs":{"Monarch":{"xref_id":"0005511"}}}


id: PBO:0013462
data:
  {"annotation_feature_type":"gene","cv_name":"misc","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"trichostatin A partially suppresses rad3delta or rad3-36 sensitivity to UV and hydroxyurea","termid":"PBO:0013462"}


id: MONDO:0003731
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A mature or immature teratoma affecting the central nervous system and occurring in adults.","definition_xrefs":["NCIT:C5794"],"direct_ancestors":[{"relation_name":"is_a","term_name":"central nervous system teratoma","termid":"MONDO:0002718"},{"relation_name":"is_a","term_name":"adult central nervous system germ cell tumor","termid":"MONDO:0003405"},{"relation_name":"is_a","term_name":"adult teratoma","termid":"MONDO:0003516"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"adult central nervous system teratoma","secondary_identifiers":["DOID:6015","MEDGEN:234583","UMLS:C1370506"],"synonyms":[{"name":"Central nervous system teratoma","type":"exact"},{"name":"adult CNS teratoma","type":"exact"},{"name":"adult central nervous system teratoma","type":"exact"},{"name":"central nervous system teratoma of adults","type":"exact"},{"name":"teratoma of adult CNS","type":"exact"},{"name":"teratoma of adult central nervous system","type":"exact"},{"name":"teratoma of the adult CNS","type":"exact"},{"name":"teratoma of the adult central nervous system","type":"exact"}],"termid":"MONDO:0003731","xrefs":{"Monarch":{"xref_id":"0003731"}}}


id: FYECO:0000373
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which thiolutin was added to the medium or assay buffer in excess compared to standard medium or assay buffers.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping excess","termid":"FYECO:0000109"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ thiolutin","termid":"FYECO:0000373"}


id: PBO:0003579
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mdm10/Mdm12/Mmm1 complex subunit Mmm1 (predicted)","termid":"PBO:0003579"}


id: GO:0044437
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. Any constituent part of a vacuole, a closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material.","definition_xrefs":["GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete vacuolar part (obsolete GO:0044437)","synonyms":[{"name":"vacuole component","type":"exact"}],"termid":"GO:0044437"}


id: PBO:0083703
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ER exit adaptor for Golgi mannosyltransferases; facilitates the exit of Kre2p, Ktr1p and Mnn4p from the ER; involved in COPII-coated vesicle cargo loading and transport; may also promote the retention of proteins in the early Golgi compartment; integral membrane protein of early Golgi and ER","termid":"PBO:0083703"}


id: PBO:0114062
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Roadblock/LC7 domain superfamily protein Mug15","termid":"PBO:0114062"}


id: MONDO:0100434
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A pathological condition resulting from chronic exposure to hypoxia at high altitude. The syndrome is characterized by an excessive number of red blood cells associated with a high blood hemoglobin concentration ([Hb]), hypoxemia, and, in some cases, pulmonary hypertension. Clinical signs include headache, fatigue, sleep disturbances, dyspnea, digestive complaints, and high risk of thrombotic events.","definition_xrefs":["EFO:0010143"],"direct_ancestors":[{"relation_name":"is_a","term_name":"altitude sickness","termid":"MONDO:0006625"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chronic mountain sickness","secondary_identifiers":["SCTID:241975000"],"synonyms":[{"name":"Monge's disease","type":"exact"}],"termid":"MONDO:0100434","xrefs":{"Monarch":{"xref_id":"0100434"}}}


id: PBO:0090459
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"translation initiation factor eIF1A-like","termid":"PBO:0090459"}


id: PBO:0084464
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition","termid":"PBO:0084464"}


id: PBO:0088436
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA-binding transcription factor","termid":"PBO:0088436"}


id: PBO:0078964
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Ser (anticodon AGA) 3-1","termid":"PBO:0078964"}


id: GO:0120525
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: choline = acetaldehyde + trimethylamine.","definition_xrefs":["RHEA:35095"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbon-nitrogen lyase activity","termid":"GO:0016840"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016829"}],"interesting_parent_ids":["GO:0003824","GO:0016829","GO:0003674"],"is_obsolete":false,"name":"choline trimethylamine lyase activity","secondary_identifiers":["MetaCyc:RXN-13946","EC:4.3.99.4","KEGG_REACTION:R10285"],"termid":"GO:0120525"}


id: PBO:0026649
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_protein_binding_during_cellular_response_to_hydroxyurea","termid":"PBO:0026649"}


id: MONDO:1011353
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Radiculitis that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inflammatory disease, non-human animal","termid":"MONDO:1011327"},{"relation_name":"is_a","term_name":"nervous system disorder, non-human animal","termid":"MONDO:1011336"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"radiculitis, non-human animal","termid":"MONDO:1011353","xrefs":{"Monarch":{"xref_id":"1011353"}}}


id: PBO:0052628
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"keratin 6B","termid":"PBO:0052628"}


id: MONDO:1011539
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hypokalaemic periodic paralysis that occurs in domestic cat.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hypokalaemic periodic paralysis, non-human animal","termid":"MONDO:1011434"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hypokalaemic periodic paralysis, domestic cat","secondary_identifiers":["OMIA:001759-9685"],"termid":"MONDO:1011539","xrefs":{"Monarch":{"xref_id":"1011539"}}}


id: GO:0047912
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: alpha-D-galacturonate + ATP = 1-phospho-alpha-D-galacturonate + ADP + 2 H+.","definition_xrefs":["EC:2.7.1.44","RHEA:12965"],"direct_ancestors":[{"relation_name":"is_a","term_name":"kinase activity","termid":"GO:0016301"},{"relation_name":"is_a","term_name":"phosphotransferase activity, alcohol group as acceptor","termid":"GO:0016773"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016301"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016301","GO:0016740"],"is_obsolete":false,"name":"galacturonokinase activity","secondary_identifiers":["KEGG_REACTION:R01980","MetaCyc:GALACTURONOKINASE-RXN"],"synonyms":[{"name":"ATP:D-galacturonate 1-phosphotransferase activity","type":"related"},{"name":"galacturonokinase (phosphorylating) D-galacturonic acid kinase activity","type":"related"}],"termid":"GO:0047912"}


id: PBO:0052845
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"keratin associated protein 4-1","termid":"PBO:0052845"}


id: PBO:0074967
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, C/D box 114-9","termid":"PBO:0074967"}


id: PBO:0082727
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of the Rix1 complex and possibly pre-replicative complexes; required for processing of ITS2 sequences from 35S pre-rRNA; component of the pre-60S ribosomal particle with the dynein-related AAA-type ATPase Mdn1p; required for pre-replicative complex (pre-RC) formation and maintenance during DNA replication licensing; relocalizes to the cytosol in response to hypoxia; essential gene","termid":"PBO:0082727"}


id: PBO:0084858
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial ribosomal protein of the large subunit; required for mitochondrial genome integrity, respiratory growth, and mitochondrial redox homeostasis, partially overlaps verified gene YPR099C","termid":"PBO:0084858"}


id: GO:0048402
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process that contributes to the act of creating the structural organization of the intermediate mesoderm. This process pertains to the physical shaping of a rudimentary structure.","definition_xrefs":["GOC:dgh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mesoderm structural organization","termid":"GO:0048338"},{"relation_name":"part_of","term_name":"intermediate mesoderm morphogenesis","termid":"GO:0048390"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"intermediate mesoderm structural organization","synonyms":[{"name":"intermediate mesoderm structural organisation","type":"exact"}],"termid":"GO:0048402"}


id: MONDO:0012239
data:
  {"annotated_genes":["SJAG_04887"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87077],"is_not":false,"summary":null,"term":"MONDO:0012239"}]},"cv_name":"mondo","definition":"Any congenital myopathy in which the cause of the disease is a mutation in the TPM3 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intermediate nemaline myopathy","termid":"MONDO:0015736"},{"relation_name":"is_a","term_name":"childhood-onset nemaline myopathy","termid":"MONDO:0015738"},{"relation_name":"is_a","term_name":"TPM3-related myopathy","termid":"MONDO:0100108"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04887":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"},{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320","MONDO:0005336"],"is_obsolete":false,"name":"congenital myopathy 4B, autosomal recessive","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:609284","DOID:0110926","MEDGEN:1840525","GARD:15453","UMLS:C5829889","MESH:C538348"],"synonyms":[{"name":"NEM1","type":"related"},{"name":"Nem1","type":"related"},{"name":"TPM3 nemaline myopathy","type":"exact"},{"name":"nemaline myopathy 1","type":"related"},{"name":"nemaline myopathy 1, autosomal dominant or recessive","type":"related"},{"name":"nemaline myopathy caused by mutation in TPM3","type":"exact"},{"name":"nemaline myopathy type 1","type":"related"}],"termid":"MONDO:0012239","terms_by_termid":{"MONDO:0012239":null},"xrefs":{"Monarch":{"xref_id":"0012239"}}}


id: GO:0004671
data:
  {"annotated_genes":["SJAG_05016"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[77319],"is_not":false,"summary":null,"term":"GO:0004671"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: S-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine = S-adenosyl-L-homocysteine + protein C-terminal S-farnesyl-L-cysteine methyl ester.","definition_xrefs":["EC:2.1.1.100"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein C-terminal carboxyl O-methyltransferase activity","termid":"GO:0003880"},{"relation_name":"is_a","term_name":"S-adenosylmethionine-dependent methyltransferase activity","termid":"GO:0008757"}],"gene_count":1,"genes_by_uniquename":{"SJAG_05016":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0008276"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0140096","GO:0008276","GO:0003824","GO:0003674","GO:0016740","GO:0016741"],"is_obsolete":false,"name":"protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["Reactome:R-HSA-9647977","GO:0018225","MetaCyc:2.1.1.100-RXN","KEGG_REACTION:R04496","Reactome:R-HSA-6788650","RHEA:21672"],"synonyms":[{"name":"S-adenosyl-L-methionine:protein-C-terminal-S-farnesyl-L-cysteine O-methyltransferase activity","type":"related"},{"name":"S-farnesylcysteine methyltransferase activity","type":"related"},{"name":"farnesyl cysteine C-terminal methyltransferase activity","type":"related"},{"name":"farnesyl-protein carboxymethyltransferase activity","type":"related"},{"name":"farnesylated protein C-terminal O-methyltransferase activity","type":"related"},{"name":"isoprenylated protein methyltransferase activity","type":"related"},{"name":"isoprenylcysteine carboxylmethyltransferase activity","type":"related"},{"name":"prenylated protein carboxyl methyltransferase activity","type":"related"},{"name":"prenylated protein methyltransferase activity","type":"related"},{"name":"prenylcysteine carboxyl methyltransferase activity","type":"related"},{"name":"prenylcysteine carboxylmethyltransferase activity","type":"related"},{"name":"prenylcysteine carboxymethyltransferase activity","type":"related"},{"name":"prenylcysteine methyltransferase activity","type":"related"},{"name":"protein C-terminal farnesylcysteine O-methyltransferase activity","type":"related"},{"name":"protein S-farnesylcysteine C-terminal methyltransferase activity","type":"related"},{"name":"protein-S-isoprenylcysteine O-methyltransferase activity","type":"exact"}],"termid":"GO:0004671","terms_by_termid":{"GO:0004671":null}}


id: PBO:0050687
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heat shock protein family A (Hsp70) member 8 pseudogene 14","termid":"PBO:0050687"}


id: PBO:0061432
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nuclear receptor subfamily 1 group H member 5, pseudogene","termid":"PBO:0061432"}


id: PBO:0029939
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-inviable_mixed_population_including_divided_and_undivided_germinated_spores,_with_elongated_germ_tubes_(obsolete_FYPO:0002298)","termid":"PBO:0029939"}


id: MONDO:0033331
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete genetic precocious puberty in female (obsolete MONDO:0033331)","secondary_identifiers":["Orphanet:435564"],"termid":"MONDO:0033331","xrefs":{"Monarch":{"xref_id":"0033331"}}}


id: GO:0000446
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The THO complex when it is acting as a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. In S. cerevisiae, it is composed of four subunits: Hpr1, Tho2, Thp2, and Mft1, while the human complex is composed of 7 subunits.","definition_xrefs":["PMID:16983072","GOC:krc","GOC:se","PMID:11060033","PMID:11979277"],"direct_ancestors":[{"relation_name":"is_a","term_name":"THO complex","termid":"GO:0000347"},{"relation_name":"is_a","term_name":"transcription elongation factor complex","termid":"GO:0008023"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005654"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005634"}],"interesting_parent_ids":["GO:0005575","GO:0005654","GO:0032991","GO:0005634"],"is_obsolete":false,"name":"nucleoplasmic THO complex","termid":"GO:0000446"}


id: GO:0010356
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (2E,6E,10E)-geranylgeranyl diphosphate + H+ + homogentisate = 6-geranylgeranyl-2-methylbenzene-1,4-diol + CO2 + diphosphate.","definition_xrefs":["EC:2.5.1.116","GOC:pz","PMID:16989822"],"direct_ancestors":[{"relation_name":"is_a","term_name":"homogentisate prenyltransferase activity","termid":"GO:0010354"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016765"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016740","GO:0016765"],"is_obsolete":false,"name":"homogentisate geranylgeranyltransferase activity","secondary_identifiers":["RHEA:38003","MetaCyc:RXN-14929"],"synonyms":[{"name":"HGGT activity","type":"exact"},{"name":"homogentisate geranylgeranyl transferase activity","type":"exact"}],"termid":"GO:0010356"}


id: GO:1990825
data:
  {"annotated_genes":["SJAG_00338"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[75738],"is_not":false,"summary":null,"term":"GO:1990825"}]},"cv_name":"molecular_function","definition":"Binding to messenger RNA (mRNA) of a specific nucleotide composition or a specific sequence motif.","definition_xrefs":["PMID:11886857"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mRNA binding","termid":"GO:0003729"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00338":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003723"}],"interesting_parent_ids":["GO:0003723","GO:0003674","GO:0005488"],"is_obsolete":false,"name":"sequence-specific mRNA binding","references_by_uniquename":{"GO_REF:0000033":null},"termid":"GO:1990825","terms_by_termid":{"GO:1990825":null}}


id: PR:000050397
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the cut12 gene in Schizosaccharomyces pombe.","definition_xrefs":["PRO:DAN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein","termid":"PR:000000001"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spindle pole body-associated protein cut12 (Schizosaccharomyces pombe)","pombase_gene_id":"SPBC649.05","synonyms":[{"name":"SPBC649.05","type":"related"},{"name":"Spom-cut12","type":"exact"},{"name":"cell untimely torn protein 12 (Schizosaccharomyces pombe)","type":"exact"},{"name":"cut12","type":"related"},{"name":"stf1","type":"related"}],"termid":"PR:000050397"}


id: PBO:0113517
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ubiquitin-binding protein; centrally regulates metabolic homeostasis and carbon utilization during nutrient limitation by managing Snf1p activity; subunit of TORC1 rapamycin-sensitive complex involved in growth control; central scaffold that holds the different components of TORC1 together; contains four HEAT repeats and seven WD-40 repeats","termid":"PBO:0113517"}


id: PBO:0083120
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1; upstream component for regulation through the small GTPase Rho5p; may form a complex with Lmo1p that acts as a GEF for Rho5p; interacts with Ino4p; cytoplasmic protein that relocates to mitochondria under oxidative stress; implicated in mitophagy; not an essential protein; DOCK proteins act as guanine nucleotide exchange factors","termid":"PBO:0083120"}


id: GO:1905962
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized cell acquires the specialized features of a glutamatergic neuron.","definition_xrefs":["GO_REF:0000086","GOC:TermGenie","PMID:24030726"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neuron differentiation","termid":"GO:0030182"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"glutamatergic neuron differentiation","termid":"GO:1905962"}


id: PATO:0002441
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A surface feature shape in which the bearer's surface is highly topographical with ridges, pits, rugosity or other surface structures.","definition_xrefs":["PATOC:AD"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ornamentation","termid":"PATO:0002440"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ornamented","termid":"PATO:0002441"}


id: MONDO:0001607
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"lymph node cancer","termid":"MONDO:0001082"},{"relation_name":"is_a","term_name":"hairy cell leukemia","termid":"MONDO:0018935"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005570","MONDO:0004992"],"is_obsolete":false,"name":"intrapelvic lymph node leukemic reticuloendotheliosis","secondary_identifiers":["DOID:12972","SCTID:93145002","ICD9:202.46","MEDGEN:509467","UMLS:C0153831"],"synonyms":[{"name":"leukemic reticuloendotheliosis involving intrapelvic lymph nodes","type":"exact"},{"name":"leukemic reticuloendotheliosis of intrapelvic lymph nodes","type":"exact"}],"termid":"MONDO:0001607","xrefs":{"Monarch":{"xref_id":"0001607"}}}


id: PBO:0083900
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Fimbrin, actin-bundling protein; cooperates with Scp1p in organization and maintenance of the actin cytoskeleton; phosphorylated by Cdc28p/Clb2p in metaphase on T103, to regulate conformation, and modulate actin filament binding affinity and actin cable dynamics; relocalizes from the plasma membrane to the cytoplasm upon DNA replication stress; human homologs PLS3 and LCP1 implicated in spinocerebellar ataxia type 2 (SCA2) can each complement yeast null mutant","termid":"PBO:0083900"}


id: GO:0071518
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 4,5-dihydroxy-pentane-2,3-dione + ATP = 5-phospho-4-hydroxy-pentane-2,3-dione (P-DPD) + ADP.","definition_xrefs":["PMID:17274596","PMID:20025244","GOC:imk"],"direct_ancestors":[{"relation_name":"is_a","term_name":"kinase activity","termid":"GO:0016301"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016301"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016740","GO:0003674","GO:0003824","GO:0016301"],"is_obsolete":false,"name":"autoinducer-2 kinase activity","secondary_identifiers":["MetaCyc:RXN0-5461","RHEA:15377"],"synonyms":[{"name":"4,5-dihydroxy-pentane-2,3-dione kinase activity","type":"exact"}],"termid":"GO:0071518"}


id: PR:O94412
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A geranylgeranyl transferase type-2 subunit alpha that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","PANTHER:PTHR11129:SF2"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"geranylgeranyl transferase type-2 subunit alpha (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC1620.05","secondary_identifiers":["UniProtKB:O94412"],"synonyms":[{"name":"GGTase-II-alpha (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"PGGT (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"SPCC1620.05","type":"related"},{"name":"Spom972h-RABGGTA","type":"exact"},{"name":"geranylgeranyl transferase type II subunit alpha (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"type II protein geranyl-geranyltransferase subunit alpha (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O94412"}


id: PR:Q09898
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- sid2 gene.","definition_xrefs":["UniProtKB:Q09898","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/threonine-protein kinase sid2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC24B11.11c","synonyms":[{"name":"Spom972h-sid2","type":"exact"}],"termid":"PR:Q09898"}


id: PBO:0054472
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1872","termid":"PBO:0054472"}


id: MONDO:0020559
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"O'Sullivan McLeod syndrome is a benign lower motor neuron disorder and a rare variant of monomelic amyotrophy (MA), characterized by an initial unilateral weakness in the intrinsic hand muscles that eventually spreads to the opposite limb (with an asymmetrical distribution) and that has a very slow progression of muscular atrophy over a 20 year period.","definition_xrefs":["Orphanet:99965"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monomelic amyotrophy","termid":"MONDO:0011224"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"O'Sullivan-McLeod syndrome","secondary_identifiers":["MEDGEN:797656","GARD:19718","MedDRA:10069682","UMLS:C2721741"],"termid":"MONDO:0020559","xrefs":{"Monarch":{"xref_id":"0020559"}}}


id: PBO:0057017
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 105-2","termid":"PBO:0057017"}


id: GO:0140251
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the presynapse.","definition_xrefs":["PMID:27764673"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation protein catabolic process at synapse","termid":"GO:0140250"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation protein catabolic process at presynapse","termid":"GO:0140251"}


id: PBO:0041458
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 10 open reading frame 82","termid":"PBO:0041458"}


id: PBO:0005862
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2.1.2.2","termid":"PBO:0005862"}


id: GO:0019234
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of events required for an organism to receive a fast pain stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. Fast pain is often subjectively described as a sharp or stabbing pain; in humans, the signals from a fast pain stimulus are perceived and relayed along myelinated A-delta fibers to the central nervous system, reaching their target in about 0.1 seconds.","definition_xrefs":["PMID:38704307"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sensory perception of pain","termid":"GO:0019233"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"sensory perception of fast pain","termid":"GO:0019234"}


id: GO:1902396
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a protein is transported to, or maintained in, a location within a bicellular tight junction.","definition_xrefs":["GOC:TermGenie","PMID:18332111"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein localization to cell-cell junction","termid":"GO:0150105"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0008150","GO:0051179"],"is_obsolete":false,"name":"protein localization to bicellular tight junction","synonyms":[{"name":"protein localisation in tight junction","type":"exact"},{"name":"protein localisation to tight junction","type":"exact"},{"name":"protein localization in tight junction","type":"exact"}],"termid":"GO:1902396"}


id: MONDO:0044705
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A squamous cell carcinoma that arises from the mucosal epithelial surface of the ethmoid, frontal, maxillary, or sphenoid sinus. Patients may present with nasal fullness, obstruction, and/or epistaxis.","definition_xrefs":["NCIT:C8193"],"direct_ancestors":[{"relation_name":"is_a","term_name":"paranasal sinus carcinoma","termid":"MONDO:0000380"},{"relation_name":"is_a","term_name":"bone squamous cell carcinoma","termid":"MONDO:0000514"},{"relation_name":"is_a","term_name":"head and neck squamous cell carcinoma","termid":"MONDO:0010150"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"paranasal sinus squamous cell carcinoma","secondary_identifiers":["GARD:17927","MEDGEN:79105","Orphanet:500464","UMLS:C0280334"],"synonyms":[{"name":"epidermoid carcinoma of paranasal sinus","type":"exact"},{"name":"epidermoid carcinoma of the paranasal sinus","type":"exact"},{"name":"paranasal sinus epidermoid carcinoma","type":"exact"},{"name":"paranasal sinus squamous cell carcinoma","type":"exact"},{"name":"squamous cell carcinoma of paranasal sinus","type":"exact"},{"name":"squamous cell carcinoma of the nasal cavity and paranasal sinuses","type":"related"},{"name":"squamous cell carcinoma of the nasal cavity and sinuses","type":"exact"},{"name":"squamous cell carcinoma of the paranasal sinus","type":"exact"}],"termid":"MONDO:0044705","xrefs":{"Monarch":{"xref_id":"0044705"}}}


id: PBO:0030555
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_lysine_import","termid":"PBO:0030555"}


id: GO:0061276
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of a mesonephric proximal tubule are generated and organized. The mesonephric proximal tubule extends from the capsule to the distal tubule.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mesonephric nephron tubule morphogenesis","termid":"GO:0061240"},{"relation_name":"is_a","term_name":"proximal tubule morphogenesis","termid":"GO:0072158"},{"relation_name":"part_of","term_name":"mesonephric proximal tubule development","termid":"GO:0061275"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mesonephric proximal tubule morphogenesis","termid":"GO:0061276"}


id: GO:0021638
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.","definition_xrefs":["GOC:dgh","GOC:cls","GOC:dph","GO_REF:0000021","GOC:jid","ISBN:0838580343"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cranial nerve formation","termid":"GO:0021603"},{"relation_name":"part_of","term_name":"trigeminal nerve morphogenesis","termid":"GO:0021636"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"trigeminal nerve formation","synonyms":[{"name":"CN V biosynthesis","type":"related"},{"name":"CN V formation","type":"related"}],"termid":"GO:0021638"}


id: PBO:0091535
data:
  {"annotation_feature_type":"gene","cv_name":"misc","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"binding affinity for ADP-bound F-actin Kd 900 nM","termid":"PBO:0091535"}


id: GO:0070262
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The removal of phosphoric residues from peptidyl-O-phospho-L-serine to form peptidyl-serine.","definition_xrefs":["GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein dephosphorylation","termid":"GO:0006470"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"peptidyl-serine dephosphorylation","termid":"GO:0070262"}


id: PBO:0090982
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/threonine protein phosphatase PP1 regulatory subunit Sds22","termid":"PBO:0090982"}


id: PBO:0011115
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiotic dynein intermediate light chain Dli1/Dil1","termid":"PBO:0011115"}


id: PBO:0063289
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protocadherin gamma subfamily B, 3","termid":"PBO:0063289"}


id: PBO:0069745
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1026, pseudogene","termid":"PBO:0069745"}


id: PBO:0057092
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 188","termid":"PBO:0057092"}


id: PBO:0080629
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WD repeat domain 76","termid":"PBO:0080629"}


id: GO:0102030
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: dTDP-6-deoxy-beta-L-mannose + NAD+ = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + NADH + H+.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete dTDP-L-rhamnose synthetase activity (obsolete GO:0102030)","termid":"GO:0102030"}


id: SO:0000317
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"Complementary DNA; A piece of DNA copied from an mRNA and spliced into a vector for propagation in a suitable host.","direct_ancestors":[{"relation_name":"has_quality","term_name":"cDNA","termid":"SO:0000756"},{"relation_name":"is_a","term_name":"clone","termid":"SO:0000151"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cDNA_clone","synonyms":[{"name":"cDNA clone","type":"exact"}],"termid":"SO:0000317"}


id: PBO:0028764
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_protein_localization_to_nuclear_periphery_during_cellular_response_to_heat","termid":"PBO:0028764"}


id: PBO:0113394
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative protein of unknown function; YMR317W is not an essential gene","termid":"PBO:0113394"}


id: PBO:0035822
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_histone_H3-K9_methylation_at_heterochromatin_island_during_vegetative_growth","termid":"PBO:0035822"}


id: PATO:0000446
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000446 absolute percentage value (obsolete PATO:0000446)","termid":"PATO:0000446"}


id: PBO:0029179
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_level_of_stress_responsive_gene_mRNA_during_vegetative_growth","termid":"PBO:0029179"}


id: GO:0061186
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the frequency, rate, or extent of heterochromatin formation at silent mating-type cassette.","definition_xrefs":["GOC:dph","PMID:10388812"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of heterochromatin formation","termid":"GO:0031452"},{"relation_name":"is_a","term_name":"regulation of silent mating-type cassette heterochromatin formation","termid":"GO:0090054"},{"relation_name":"negatively_regulates","term_name":"silent mating-type cassette heterochromatin formation","termid":"GO:0030466"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006325"},{"rel_name":"negatively_regulates","termid":"GO:0006325"},{"rel_name":"positively_regulates","termid":"GO:0010467"},{"rel_name":"regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0010467","GO:0006325","GO:0008150"],"is_obsolete":false,"name":"negative regulation of silent mating-type cassette heterochromatin formation","synonyms":[{"name":"negative regulation of chromatin silencing at silent mating-type cassette","type":"exact"},{"name":"negative regulation of silent mating-type cassette heterochromatin assembly","type":"exact"}],"termid":"GO:0061186"}


id: PBO:0001759
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribonucleotide reductase (RNR) inhibitor family","termid":"PBO:0001759"}


id: PBO:0041631
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CACNA1C antisense RNA 1","termid":"PBO:0041631"}


id: PBO:0027547
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_cell_population_growth_on_non-fermentable_carbon_source","termid":"PBO:0027547"}


id: PBO:0058494
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 5689","termid":"PBO:0058494"}


id: GO:0140958
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a miRNA is targeted for degradation by a non-coding RNA or mRNA. The binding of an RNA to a target miRNA within a RISC complex results in either ubiquitin-mediated degradation of AGO protein or the displacement of the 3' end of the miRNA, exposing it to nucleases.","definition_xrefs":["PMID:36150386","PMID:33184237"],"direct_ancestors":[{"relation_name":"is_a","term_name":"miRNA catabolic process","termid":"GO:0010587"},{"relation_name":"is_a","term_name":"post-transcriptional gene silencing","termid":"GO:0016441"},{"relation_name":"is_a","term_name":"negative regulation of miRNA-mediated gene silencing","termid":"GO:0060965"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"negatively_regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"target-directed miRNA degradation","synonyms":[{"name":"TDMD","type":"exact"},{"name":"target-directed microRNA degradation","type":"exact"}],"termid":"GO:0140958"}


id: MONDO:0009053
data:
  {"annotated_genes":["SJAG_00660","SJAG_03457"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[89179,89180],"is_not":false,"summary":null,"term":"MONDO:0009053"}]},"cv_name":"mondo","definition":"ALDH18A1-related De Barsy syndrome combines intellectual deficit, bilateral cataracts, and skin and joint hyperlaxity.","definition_xrefs":["Orphanet:35664"],"direct_ancestors":[{"relation_name":"is_a","term_name":"developmental anomaly of metabolic origin","termid":"MONDO:0015327"},{"relation_name":"is_a","term_name":"de Barsy syndrome","termid":"MONDO:0017569"},{"relation_name":"is_a","term_name":"P5CS deficiency","termid":"MONDO:0100126"},{"relation_name":"is_a","term_name":"inherited cutis laxa","termid":"MONDO:0100237"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00660":null,"SJAG_03457":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0019303"},{"rel_name":"is_a","termid":"MONDO:0004736"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0019303","MONDO:0004736","MONDO:0006025"],"is_obsolete":false,"name":"ALDH18A1-related de Barsy syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["ICD9:371.89","MEDGEN:1720006","OMIM:219150","DOID:0070132","SCTID:59252009","GARD:16638","UMLS:C5234852"],"synonyms":[{"name":"ARCL3A","type":"exact"},{"name":"De Barsy syndrome A","type":"exact"},{"name":"De Barsy syndrome a","type":"related"},{"name":"Delta-1-pyrroline 5-carboxylate synthetase deficiency","type":"exact"},{"name":"P5CS deficiency","type":"broad"},{"name":"autosomal recessive cutis laxa type IIIA","type":"related"},{"name":"cutis laxa, autosomal recessive, type 3A","type":"related"},{"name":"cutis laxa, autosomal recessive, type IIIA","type":"related"},{"name":"cutis laxa, corneal clouding, and intellectual disability","type":"related"},{"name":"cutis laxa, corneal clouding, and mental retardation","type":"related"},{"name":"neurocutaneous syndrome, Bicknell type","type":"exact"},{"name":"progeroid syndrome of De Barsy","type":"related"}],"termid":"MONDO:0009053","terms_by_termid":{"MONDO:0009053":null},"xrefs":{"Monarch":{"xref_id":"0009053"}}}


id: MONDO:0024309
data:
  {"annotated_genes":["SJAG_00773"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86985],"is_not":false,"summary":null,"term":"MONDO:0024309"}]},"cv_name":"mondo","definition":"A hereditary sensory and autonomic neuropathy type 2 characterized by progressive sensory neuropathy with onset in childhood that has material basis in mutation in the HSN2 isoform of the WNK1 gene on chromosome 12p13","definition_xrefs":["DOID:0070155"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary sensory and autonomic neuropathy type 2","termid":"MONDO:0019941"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00773":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0005244"],"is_obsolete":false,"name":"neuropathy, hereditary sensory and autonomic, type 2A","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:416701","GARD:15129","OMIM:201300","UMLS:C2752089"],"synonyms":[{"name":"HSAN 2A","type":"exact"},{"name":"HSAN2A","type":"exact"},{"name":"HSN 2A","type":"exact"},{"name":"Morvan disease","type":"related"},{"name":"acroosteolysis, Giaccai type","type":"related"},{"name":"acroosteolysis, neurogenic","type":"related"},{"name":"hereditary sensory and autonomic neuropathy type 2A","type":"related"},{"name":"hereditary sensory and autonomic neuropathy type IIA","type":"exact"},{"name":"neuropathy, congenital sensory","type":"related"},{"name":"neuropathy, hereditary sensory and autonomic, type II","type":"exact"},{"name":"neuropathy, hereditary sensory and autonomic, type IIA","type":"exact"},{"name":"neuropathy, hereditary sensory radicular, autosomal recessive","type":"related"},{"name":"neuropathy, hereditary sensory, type 2A","type":"exact"},{"name":"neuropathy, progressive sensory, of children","type":"related"}],"termid":"MONDO:0024309","terms_by_termid":{"MONDO:0024309":null},"xrefs":{"Monarch":{"xref_id":"0024309"}}}


id: PBO:0071964
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S6 kinase A3","termid":"PBO:0071964"}


id: SO:1001259
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A CDS that is supported by similarity to EST or cDNA data.","definition_xrefs":["SO:xp"],"direct_ancestors":[{"relation_name":"has_quality","term_name":"supported_by_EST_or_cDNA","termid":"SO:0000909"},{"relation_name":"is_a","term_name":"CDS_supported_by_sequence_similarity_data","termid":"SO:1001251"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CDS_supported_by_EST_or_cDNA_data","synonyms":[{"name":"CDS supported by EST or cDNA data","type":"exact"}],"termid":"SO:1001259"}


id: PBO:0038727
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"actin gamma 1 pseudogene 22","termid":"PBO:0038727"}


id: GO:0030961
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The hydroxylation of peptidyl-arginine to form peptidyl-hydroxyarginine.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"peptidyl-arginine modification","termid":"GO:0018195"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"peptidyl-arginine hydroxylation","termid":"GO:0030961"}


id: GO:0071495
data:
  {"annotated_genes":["SJAG_01805","SJAG_04332","SJAG_01837","SJAG_03048","SJAG_04140","SJAG_04183","SJAG_00082"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[113194,91948,118678,104336,95755],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140429"},{"annotations":[106112],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0072429"},{"annotations":[104345],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0072441"},{"annotations":[104346],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990820"},{"annotations":[104347,96495],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0072435"}]},"cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to endogenous stimulus","termid":"GO:0009719"}],"gene_count":7,"genes_by_uniquename":{"SJAG_00082":null,"SJAG_01805":null,"SJAG_01837":null,"SJAG_03048":null,"SJAG_04140":null,"SJAG_04183":null,"SJAG_04332":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to endogenous stimulus","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-9860931"],"termid":"GO:0071495","terms_by_termid":{"GO:0072429":null,"GO:0072435":null,"GO:0072441":null,"GO:0140429":null,"GO:1990820":null}}


id: PBO:0088154
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Very long chain fatty acyl-CoA synthetase and fatty acid transporter; activates imported fatty acids with a preference for very long lengths (C20-C26); has a separate function in the transport of long chain fatty acids","termid":"PBO:0088154"}


id: GO:1900498
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA catabolic process to butanol.","definition_xrefs":["GOC:mengo_curators","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of amide metabolic process","termid":"GO:0034249"},{"relation_name":"is_a","term_name":"negative regulation of fatty acid metabolic process","termid":"GO:0045922"},{"relation_name":"is_a","term_name":"negative regulation of nucleobase-containing compound metabolic process","termid":"GO:0045934"},{"relation_name":"is_a","term_name":"negative regulation of phosphate metabolic process","termid":"GO:0045936"},{"relation_name":"is_a","term_name":"negative regulation of lipid catabolic process","termid":"GO:0050995"},{"relation_name":"is_a","term_name":"negative regulation of lipid biosynthetic process","termid":"GO:0051055"},{"relation_name":"is_a","term_name":"negative regulation of sulfur metabolic process","termid":"GO:0051175"},{"relation_name":"is_a","term_name":"regulation of butyryl-CoA catabolic process to butanol","termid":"GO:1900497"},{"relation_name":"is_a","term_name":"negative regulation of alcohol biosynthetic process","termid":"GO:1902931"},{"relation_name":"negatively_regulates","term_name":"butyryl-CoA catabolic process to butanol","termid":"GO:0044582"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0055086"},{"rel_name":"negatively_regulates","termid":"GO:0006790"},{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"negatively_regulates","termid":"GO:0044281"},{"rel_name":"regulates","termid":"GO:0006790"},{"rel_name":"regulates","termid":"GO:0006629"},{"rel_name":"negatively_regulates","termid":"GO:0055086"}],"interesting_parent_ids":["GO:0006790","GO:0006629","GO:0044281","GO:0008150","GO:0055086"],"is_obsolete":false,"name":"negative regulation of butyryl-CoA catabolic process to butanol","synonyms":[{"name":"down regulation of butyryl-CoA catabolic process to butanol","type":"exact"},{"name":"down regulation of butyryl-CoA catabolism to butanol","type":"exact"},{"name":"down-regulation of butyryl-CoA catabolic process to butanol","type":"exact"},{"name":"down-regulation of butyryl-CoA catabolism to butanol","type":"exact"},{"name":"downregulation of butyryl-CoA catabolic process to butanol","type":"exact"},{"name":"downregulation of butyryl-CoA catabolism to butanol","type":"exact"},{"name":"inhibition of butyryl-CoA catabolic process to butanol","type":"narrow"},{"name":"inhibition of butyryl-CoA catabolism to butanol","type":"exact"},{"name":"negative regulation of butyryl-CoA catabolism to butanol","type":"exact"}],"termid":"GO:1900498"}


id: MOD:01339
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces a hydrogen atom with an ethyl group.","definition_xrefs":["PubMed:9629898","Unimod:280"],"direct_ancestors":[{"relation_name":"is_a","term_name":"alkylated residue","termid":"MOD:00001"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ethylated residue","synonyms":[{"name":"EtRes","type":"exact"},{"name":"Ethyl","type":"related"},{"name":"Ethylation","type":"related"}],"termid":"MOD:01339"}


id: GO:0007010
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id: GO:1905912
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  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of calcium ion export across the plasma membrane.","definition_xrefs":["PMID:22362515","GOC:BHF_miRNA","GO_REF:0000058","GOC:BHF","GOC:TermGenie","GOC:rph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of calcium ion transmembrane transport","termid":"GO:1903169"},{"relation_name":"regulates","term_name":"calcium ion export across plasma membrane","termid":"GO:1990034"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0055085"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0055085","GO:0006810"],"is_obsolete":false,"name":"regulation of calcium ion export across plasma membrane","synonyms":[{"name":"regulation of calcium ion efflux from cell","type":"exact"},{"name":"regulation of calcium ion export from cell","type":"exact"}],"termid":"GO:1905912"}


id: PBO:0060471
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nicotinamide phosphoribosyltransferase pseudogene 1","termid":"PBO:0060471"}


id: GO:0019632
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid. It is an important intermediate in the biosynthesis of aromatic amino acids.","definition_xrefs":["ISBN:0198547684","GOC:sm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monocarboxylic acid metabolic process","termid":"GO:0032787"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0044281"],"is_obsolete":false,"name":"shikimate metabolic process","synonyms":[{"name":"shikimate metabolism","type":"exact"}],"termid":"GO:0019632"}


id: PBO:0027201
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-long_nuclear_microtubules_protruding_through_nuclear_envelope_during_interphase","termid":"PBO:0027201"}


id: PBO:0116405
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"plasma membrane P-type ATPase, calcium transporting, P2 type, Pmc1","termid":"PBO:0116405"}


id: PBO:0086325
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein with similarity to mammalian monocarboxylate permeases; monocarboxylate permeases are involved in transport of monocarboxylic acids across the plasma membrane but mutant is not deficient in monocarboxylate transport","termid":"PBO:0086325"}


id: PBO:0050915
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"interferon induced transmembrane protein 1","termid":"PBO:0050915"}


id: PBO:0034236
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-tracheates","termid":"PBO:0034236"}


id: PBO:0028953
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-T-shaped_cell_during_recovery_from_stationary_phase","termid":"PBO:0028953"}


id: FYPO:0007848
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which microtubules self-assemble into a spindle without the participation of the spindle pole body (SPB) during one or both meiotic nuclear divisions. This phenotype is observed in the absence of both bouquet formation and meiotic SPB insertion into the nuclear envelope.","definition_xrefs":["PMID:34346498","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal meiotic spindle assembly","termid":"FYPO:0000737"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"part_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000054"},{"rel_name":"part_of","termid":"FYPO:0000631"},{"rel_name":"part_of","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000054","FYPO:0000002","FYPO:0005447","FYPO:0000631","FYPO:0001985"],"is_obsolete":false,"name":"meiotic spindle self-assembly","synonyms":[{"name":"SPB-independent meiotic spindle assembly","type":"exact"},{"name":"SPB-independent spindle assembly during meiosis","type":"exact"},{"name":"acentrosomal meiotic spindle assembly","type":"related"},{"name":"acentrosomal spindle assembly during meiosis","type":"related"},{"name":"meiotic SPB-independent spindle","type":"related"},{"name":"spindle pole body-independent meiotic spindle assembly","type":"exact"},{"name":"spindle pole body-independent spindle assembly during meiosis","type":"exact"},{"name":"spindle self-assembly during meiosis","type":"exact"},{"name":"spindle self-assembly during meiotic nuclear division","type":"exact"}],"termid":"FYPO:0007848"}


id: GO:0034238
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The binding and fusion of a macrophage to one or more other cells to form a multinucleated cell.","definition_xrefs":["GOC:sl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syncytium formation by plasma membrane fusion","termid":"GO:0000768"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"macrophage fusion","termid":"GO:0034238"}


id: GO:0044463
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.","definition_xrefs":["GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete cell projection part (obsolete GO:0044463)","termid":"GO:0044463"}


id: PBO:0047801
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"forkhead box J1","termid":"PBO:0047801"}


id: MONDO:0001206
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"glaucoma","termid":"MONDO:0005041"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"aqueous misdirection","secondary_identifiers":["UMLS:C1135189","ICD10CM:H40.83","DOID:11149","ICD9:365.83","MEDGEN:1843475"],"termid":"MONDO:0001206","xrefs":{"Monarch":{"xref_id":"0001206"}}}


id: PBO:0059090
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MORC2 antisense RNA 1","termid":"PBO:0059090"}


id: MONDO:0800451
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"inherited aplastic anemia","termid":"MONDO:0001713"},{"relation_name":"is_a","term_name":"inherited thrombocytopenia","termid":"MONDO:0100241"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"congenital amegakaryocytic thrombocytopenia","secondary_identifiers":["UMLS:C1327915","MEDGEN:272171","icd11.foundation:801723173","OMIMPS:604498"],"synonyms":[{"name":"congenital amegakaryocytic thrombocytopenia","type":"exact"}],"termid":"MONDO:0800451","xrefs":{"Monarch":{"xref_id":"0800451"}}}


id: PBO:0028906
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_transcription_during_cellular_response_to_calcium_ion","termid":"PBO:0028906"}


id: PBO:0086776
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative protein of unknown function; SWAT-GFP and mCherry fusion proteins localize to the cytosol","termid":"PBO:0086776"}


id: PBO:0068281
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribonuclease H1 pseudogene 2","termid":"PBO:0068281"}


id: PR:O42866
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A carbonyl reductase family member 4 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO01330","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3-oxoacyl-[acyl-carrier-protein] reductase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC3G9.02","secondary_identifiers":["UniProtKB:O42866"],"synonyms":[{"name":"3-ketoacyl-acyl carrier protein reductase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-CBR4","type":"exact"}],"termid":"PR:O42866"}


id: FYPO:0006699
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of hercynylcysteine sulfoxide measured in a cell is lower than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased level of substance in cell during vegetative growth","termid":"FYPO:0001329"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001985","FYPO:0001320"],"is_obsolete":false,"name":"decreased cellular hercynylcysteine sulfoxide level during vegetative growth","synonyms":[{"name":"decreased cellular hercynylcysteine sulfoxide level during mitotic cell cycle","type":"related"},{"name":"decreased cellular hercynylcysteine sulphoxide level during vegetative growth","type":"exact"},{"name":"decreased hercynylcysteine sulfoxide level during vegetative growth","type":"exact"},{"name":"reduced cellular hercynylcysteine sulfoxide level during vegetative growth","type":"exact"}],"termid":"FYPO:0006699"}


id: MONDO:0035499
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare genetic primary lymphedema characterized by unilateral or bilateral lower limb lymphedema of variable severity. The condition shows almost complete penetrance with onset in childhood or adolescence in females, whereas in males it shows incomplete penetrance with later onset of disease. Lymphoscintigraphy in more severely affected individuals reveals lymphatic abnormalities consistent with lymphangiectasia, valve dysfunction, and thoracic duct reflux.","definition_xrefs":["Orphanet:569816"],"direct_ancestors":[{"relation_name":"is_a","term_name":"primary lymphedema","termid":"MONDO:0019175"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"CELSR1-related late-onset primary lymphedema","secondary_identifiers":["GARD:22306","MEDGEN:1802645","UMLS:C5681848"],"termid":"MONDO:0035499","xrefs":{"Monarch":{"xref_id":"0035499"}}}


id: PBO:0039180
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"A-kinase anchoring protein 10","termid":"PBO:0039180"}


id: GO:0019575
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways resulting in the breakdown of sucrose, catalyzed by the enzyme beta-fructofuranosidase (EC:3.2.1.26).","definition_xrefs":["GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete sucrose catabolic process, using beta-fructofuranosidase (obsolete GO:0019575)","synonyms":[{"name":"sucrose breakdown, using beta-fructofuranosidase","type":"exact"},{"name":"sucrose catabolic process, using beta-fructofuranosidase","type":"exact"},{"name":"sucrose catabolism, using beta-fructofuranosidase","type":"exact"},{"name":"sucrose degradation, using beta-fructofuranosidase","type":"exact"}],"termid":"GO:0019575"}


id: PBO:0078986
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA suppressor (anticodon CTA) 2-1","termid":"PBO:0078986"}


id: PBO:0074379
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SMG1 pseudogene 5","termid":"PBO:0074379"}


id: PBO:0004477
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Nem1-Spo7 phosphatase complex catalytic subunit Nem1 (predicted)","termid":"PBO:0004477"}


id: GO:0019181
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: a halohydrin = an epoxide + a hydrogen halide.","definition_xrefs":["PMID:8017917"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbon-halide lyase activity","termid":"GO:0016848"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016829"}],"interesting_parent_ids":["GO:0016829","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"halohydrin hydrogen-halide-lyase activity","termid":"GO:0019181"}


id: PBO:0092023
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA Proline (ugg), mitochondrial","termid":"PBO:0092023"}


id: MONDO:0004720
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A orthopoxvirus that causes a milder clinical syndrome than smallpox.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"smallpox","termid":"MONDO:0004651"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"variola minor infection","secondary_identifiers":["NCIT:C34365","UMLS:C0001906","SCTID:72294005","MEDGEN:1393","DOID:9153","ICD9:050.1"],"synonyms":[{"name":"Variola minor","type":"exact"},{"name":"alastrim","type":"exact"},{"name":"cottonpox","type":"exact"},{"name":"milkpox","type":"exact"},{"name":"whitepox","type":"exact"}],"termid":"MONDO:0004720","xrefs":{"Monarch":{"xref_id":"0004720"}}}


