https://sourceforge.net/apps/trac/pombase/wiki/AntoniasCuratedPapers https://sourceforge.net/apps/trac/pombase/wiki/AntoniasDoubleMutants [[BR]] ||2038319||http://curation.pombase.org/pombe/curs/468db0c3950bdbf6|| ||ste6 | gap1 ||elongated during nitrogen starvation||ste6-delta, gap1-delta|| ||ral2 | gap1 ||elongated d|||| [[BR]] ||8804400||http://curation.pombase.org/pombe/curs/d8d3bfcf3cf532c6|| ||git5 | gpa1||conjugation abolished||double deletion, cga|| ||git5 | ras1||spheroid cells||double deletion, EMM, cga|| ||git5 | ras1||abolished conjugation||double deletion, EMM, cga|| ||git5 | ras1||spheroid cells||git5-OP, ras1-delta, EMM, cga|| ||git5 | ras1||abolished conjugation||git5-OP, ras1-delta, EMM, cga|| ||git5 | gpa2||increased conjugation||double deletion, MEA or YE, cga|| ||git5 | gpa2||increased sporulation||double deletion, MEA or YE, cga|| [[BR]] ||8887550||http://curation.pombase.org/pombe/curs/0e9fdcae51e973b7|| ||cwg2 | cdc42||cell lysis ||cwg2-1, cdc42-OP, high temp|| ||cwg2 | cdc42||cell lysis ||cwg2-1, cdc42G12V-OP, high temp| ||cwg2 | cdc42||cell lysis ||cwg2-1, cdc42Q61L-OP, high temp| ||cwg2 | rho1||cell lysis ||cwg2-1, rho1-OP, high temp|| ||cwg2 | rho1||cell lysis ||cwg2-1, rho1G15V-OP, high temp|| ||cwg2 | rho1||cell lysis ||cwg2-1, rho1Q64L-OP, high temp|| ||cwg2 | cdc42||decreased (1-3)f-D-glucan synthase activity ||cwg2-1, cdc42-OP, high temp, EMM, sorbitol added, GTP added|| ||cwg2 | cdc42||decreased (1-3)f-D-glucan synthase activity ||cwg2-1, cdc42G12V-OP, high temp, EMM, sorbitol added, GTP added|| ||cwg2 | cdc42||decreased (1-3)f-D-glucan synthase activity ||cwg2-1, cdc42Q61L-OP, high temp, EMM, sorbitol added, GTP added|| ||cwg2 | rho1||increased (1-3)f-D-glucan synthase activity ||cwg2-1, rho1-OP, high temp, EMM, sorbitol added, GTP added|| ||cwg2 | rho1||increased (1-3)f-D-glucan synthase activity ||cwg2-1, rho1G15V-OP, high temp, EMM, sorbitol added, GTP added|| ||cwg2 | rho1||increased (1-3)f-D-glucan synthase activity ||cwg2-1, rho1Q64L-OP, high temp, EMM, sorbitol added, GTP added|| ||cwg2 | rho1||increased (1-3)f-D-glucan synthase activity ||cwg2-1, rho1G15V-OP, high temp, EMM, sorbitol added|| ||cwg2 | rho1||increased (1-3)f-D-glucan synthase activity ||cwg2-1, rho1Q64L-OP, high temp, EMM, sorbitol added|| [[BR]] ||8887552||http://curation.pombase.org/pombe/curs/f1afdd21aae916be|| ||cdc2 | spd1|| small vegetative cells (wee) ||cdc2-3w, spd1-delta, microscopy|| ||cdc2 | spd1|| small vegetative cells (wee) ||cdc2-3w, spd1-delta|| ||cig2 | spd1|| normal cell shape ||cig2-delta, spd1-delta, microscopy|| ||cig2 | spd1|| normal cell size ||cig2-delta, spd1-delta|| ||cdc10 | spd1|| normal aerobic growth on glucose ||cdc10-129, spd1-delta, cga, standard temp, agar|| ||cdc10 | spd1|| normal aerobic growth on glucose ||cdc10-129, spd1-delta, cga, standard temp, agar|| ||cdc10 | spd1|| normal aerobic growth on glucose ||cdc10-129, spd1-delta, cga, high temp, agar|| ||cdc10 | spd1|| normal aerobic growth on glucose ||cdc10-129, spd1-delta, cga, high temp, agar|| [[BR]] ||8887647||http://curation.pombase.org/pombe/curs/ec1e2e8292ae5f6e|| ||mal2| nda2||inviable, spores germinate but cannot divide||mal2-1, nda2-KM52, CGA, high penetrance || ||mal2| nda2||inviable, multiple cell divisions||mal2-1, nda2-KM52, CGA, low penetrance || ||mal2| nda3||normal cell growth||mal2-1, nda3-KM311, CGA, standard temp || ||mal2| nda3||sensitive to high temp||mal2-1, nda3-KM311, CGA|| ||mal2| nda3||sensitive to low temp||mal2-1, nda3-KM311, CGA || [[BR]] ||8887553||http://curation.pombase.org/pombe/curs/c5bcc1ff40b42c22|| ||cdc1 | cdc6 ||normal growth||cdc1-18, cdc6-OP, agar, thiamine added|| ||cdc1 | cdc6 ||normal growth||cdc1-M78, cdc6-OP, agar, thiamine added|| ||cdc1 | cdc6 ||inviable following spore germination, 1-3 cell divisions and elongated||cdc1-P13(D389G), cdc6-121(unknown), standard temp|| ||cdc1 | cdc27 ||normal veg cell growth||cdc1-OP, cdc27-P11(unknown), agar, standard temp|| ||cdc1 | cdc27 ||inviable veg cells||cdc1-delta, cdc27-OP|| ||cdc1 | cdc27 ||slow cell growth||cdc1-P13(D389G), cdc27-OP|| ||cdc1 | cdc27 ||elongated cells||cdc1-P13(D389G), cdc27-OP|| ||cdc27 | rad1 ||inviable vegetative cells cells||cdc27-P11(unknown), radl-1, high temp|| ||cdc27 | rad3 ||inviable vegetative cells cells||cdc27-P11(unknown), rad3-136, high temp|| ||cdc27 | rad9 ||inviable vegetative cells cells||cdc27-P11(unknown), rad9-192, high temp|| ||cdc27 | rad17 ||inviable vegetative cells cells||cdc27-P11(unknown), radl7-W, high temp|| ||cdc27 | hus1 ||inviable vegetative cells cells||cdc27-P11(unknown), husl-14, high temp|| ||cdc27 | rad27 ||inviable vegetative cells cells||cdc27-P11(unknown), rad27-delta, high temp|| ||cdc27 | rad1 ||viable vegetative cells cells||cdc27-P11(unknown), radl-1, standard temp|| ||cdc27 | rad3 ||viable vegetative cells cells||cdc27-P11(unknown), rad3-136, standard temp|| ||cdc27 | rad9 ||viable vegetative cells cells||cdc27-P11(unknown), rad9-192, standard temp|| ||cdc27 | rad17 ||viable vegetative cells cells||cdc27-P11(unknown), radl7-W, standard temp|| ||cdc27 | hus1 ||viable vegetative cells cells||cdc27-P11(unknown), husl-14, standard temp|| ||cdc27 | rad27 ||viable vegetative cells cells||cdc27-P11(unknown), rad27-delta, standard temp|| ||cdc1 | rad1 ||inviable germinating spores, 2-5 cell divisions||cdc1-P13(D389G), radl-1, standard temp|| ||cdc1 | rad3 ||inviable germinating spores, 2-5 cell divisions||cdc1-P13(D389G), rad3-136, standard temp|| ||cdc1 | rad9 ||inviable germinating spores, 2-5 cell divisions||cdc1-P13(D389G), rad9-192, standard temp|| ||cdc1 | rad17 ||inviable germinating spores, 2-5 cell divisions||cdc1-P13(D389G), radl7-W, standard temp|| ||cdc1 | hus1 ||inviable germinating spores, 2-5 cell divisions||cdc1-P13(D389G), husl-14, standard temp|| ||cdc1 | rad27 ||decreased cell growth||cdc1-P13(D389G), rad27-delta, standard temp|| ||cdc1 | rad27 ||shorter than normal cells||cdc1-P13(D389G), rad27-delta, standard temp|| ||cdc1 | rad27 ||inviable germinating spores, 2-5 cell divisions||cdc1-P13(D389G), rad27-delta, high temp|| [[BR]] ||9197411||http://curation.pombase.org/pombe/curs/f1d8eeb553561925|| ||ade6 | ura4 | leu1||sensitive to high pH (abolsihed growth)||CGA, EMM, liquid, ade6-216, ura4-D18, leu1-32|| ||pub1 | ade6 | ura4 | leu1||sensitive to high pH (almost abolished)||CGA, EMM, liquid, pub1-1, ade6-216, ura4-D18, leu1-32|| ||pub1 | elp3 | ade6 | ura4 | leu1||sensitive to high pH (decreased growth)||CGA, EMM, liquid, pub1-1, elp3-1, ade6-216, ura4-D18, leu1-32|| ||sod1 | ade6 | ura4 | leu1||sensitive to lithium ||CGA, EMM, liquid, sod1-delta, ade6-216, ura4-D18, leu1-32|| ||pub1 | ade6 | ura4 | leu1 ||sensitive to lithium ||CGA, deletion, EMM, liquid, pub1-1, ade6-216, ura4-D18, leu1-32|| ||elp3 | ade6 | ura4 | leu1 ||normal growth on lithium||CGA, deletion, EMM, liquid, elp3-1, ade6-216, ura4-D18, leu1-32|| ||sod2 | pub1 | ade6 | ura4 | leu1 ||sensitive to lithium ||CGA, deletion, EMM, liquid, sod2-delta, pub1-1, ade6-216, ura4-D18, leu1-32|| ||sod2 | elp3 | ade6 | ura4 | leu1 ||sensitive to lithium ||CGA, deletion, EMM, liquid, sod2-delta, elp3-1, ade6-216, ura4-D18, leu1-32|| ||elp3 | pub1||normal growth at low pH||micro, elp3-1, pub1-1(OP), standard temp, emm, agar|| ||elp3 | pub1||sensitive to low pH||micro, elp3-1, pub1-1, standard temp, emm, agar|| ||elp3 | pub1||elongated vegetative cells||micro, elp3-1, pub1-1, standard temp, emm|| [[BR]] ||9203579||http://curation.pombase.org/pombe/curs/583bc6e2762656b4|| ||cdc7||long multinucleate inviable||cdc7-24,cdc7(K38R)OP, micro|| ||cdc7 | spg1 ||normal morphology||cdc7-24,cdc7(K38R)OP, spg1-OP, micro|| ||cdc7 | spg1 ||normal growth at high temp||cdc7-OP,spg1-B8, cga, high temp|| ||cdc7 | spg1 ||decreased growth on glucose||cdc7-OP,spg1-delta, cga|| ||cdc7 | spg1 ||viable binucleate septate cells||cdc7-OP,spg1-delta, cga, emm|| ||cdc2| spg1 || increased septation index ||cdc2-17, spg1-OP|| ||cdc2| spg1 || septated mononucleate cells ||cdc2-17, spg1-OP|| ||cdc2| spg1 || (septation in the absence of nuclear division)||cdc2-17, spg1-OP|| ||cdc10| spg1 || septated mononucleate cells||cdc10-V50, spg1-OP|| ||cdc15| spg1 || abolished septum formation||cdc15-140, spg1-OP|| ||cdc16| spg1 || multiseptate||cdc16-116, spg1-OP, micro, high temp|| ||cdc11| spg1 || multiseptate||cdc11-136, spg1-OP|| ||cdc7| spg1 || abolished septum formation||cdc7-delta, spg1-OP|| ||cdc16| spg1 || viable||cdc16-116, spg1-B8, high temp|| ||spg1 | cdc7 ||decreased growth|| cdc7-24, spg1-B8, agar, ye, low temp|| ||spg1 | cdc7 ||inviable|| cdc7-24, spg1-B8, agar, ye, standard temp|| ||spg1 | cdc7 ||inviable at high temp|| cdc7-24, spg1-B8, agar, ye, high temp|| ||spg1 | cdc7 ||decreased growth|| cdc7-A20, spg1-B8, agar, ye, low temp|| ||spg1 | cdc7 ||inviable|| cdc7-A20, spg1-B8, agar, ye, standard temp|| ||spg1 | cdc7 ||inviable at high temp|| cdc7-A20, spg1-B8, agar, ye, high temp|| ||spg1 | cdc11 ||decreased growth|| cdc11-136, spg1-B8, agar, ye, low temp|| ||spg1 | cdc11 ||inviable|| cdc11-136, spg1-B8, agar, ye, standard temp|| ||spg1 | cdc11 ||inviable at high temp|| cdc11-136, spg1-B8, agar, ye, high temp|| ||spg1 | cdc14 ||decreased growth|| cdc14-118, spg1-B8, agar, ye, low temp|| ||spg1 | cdc14 ||inviable|| cdc14-118, spg1-B8, agar, ye, standard temp|| ||spg1 | cdc14 ||inviable at high temp|| cdc14-118, spg1-B8, agar, ye, high temp|| ||spg1 | cdc15 ||decreased growth|| cdc15-140, spg1-B8, agar, ye, low temp|| ||spg1 | cdc15 ||inviable|| cdc15-140, spg1-B8, agar, ye, standard temp|| ||spg1 | cdc15 ||inviable at high temp|| cdc15-140, spg1-B8, agar, ye, high temp|| ||spg1 | cdc15 ||decreased growth|| cdc16-116, spg1-B8, agar, ye, low temp|| ||spg1 | cdc15 ||decreased growth|| cdc16-116, spg1-B8, agar, ye, standard temp|| ||spg1 | cdc15 ||decreased growth at high temp|| cdc16-116, spg1-B8, agar, ye, high temp|| [[BR]] ||2107403||http://curation.pombase.org/pombe/curs/e80c868d6c0d1ca5|| ||ste6 | ras1 ||normal formation of diploid zygotes||ste6-delta, ras1-val17|| ||ste6 | ras1 ||shmoos with long tips||ste6-delta, ras1-val17|| ||ste6 | ras1 ||increased conjugation frequency||ste6-delta, ras1-val17|| ||ste6 | ras1 ||decreased mating efficiency||ste6-delta, ras1-val17|| [[BR]] ||1340462||http://curation.pombase.org/pombe/curs/34d8f97a921167ba|| ||cgs1 | gpa2 ||increased cellular cAMP level||annotation_extension=has_expressivity(FYPO_EXT:0000003) cgs2-delta, gpa2-delta || ||cgs1 | gpa2 ||increased cellular cAMP level||annotation_extension=has_expressivity(FYPO_EXT:0000001) cgs2-delta, gpa2-R176H || ||cgs1 | gpa2 ||increased cellular cAMP level||annotation_extension=has_expressivity(FYPO_EXT:0000001) cgs2-delta, gpa2-Q202L || [[BR]] ||1563349||http://curation.pombase.org/pombe/curs/69403b8ceb819841|| ||rad1 | cdc17 ||inviable at high temp||high temp, cga, rad1-1, cdc17-K42 || ||rad1 | wee1 ||inviable at high temp||high temp, cga, rad1-1, wee1-50 || ||rad1 | wee1 ||viable vegetative cells||standard temp, cga, rad1-1, wee1-50 || ||rad1 | wee1 ||multinucleate||high temp, cga, rad1-1, wee1-50 || ||rad1 | wee1 ||misshapen nuclei||high temp, cga, rad1-1, wee1-50 || [[BR]] ||1594599||http://curation.pombase.org/pombe/curs/38560610372534b4|| ||rad3||elongated vegetative cells||rad3-136, rad3-OP, micro|| ||rad3||normal growth on HU||rad3-136, rad3-OP, CGA|| [[BR]] ||1464319||http://curation.pombase.org/pombe/curs/65c76fa511461156|| ||pyp1 | pyp2 ||abolished spore germination||pyp1-delta, pyp2-delta, cga|| ||pyp1 | cdc25 ||small viable vegetative cells||pyp1-delta, cdc25-22, standard, micro|| ||pyp2 | wee1 ||elongated viable cells||pyp2-delta, wee1-50-OP, standard temp, micro|| ||pyp1 | nim1 ||wee cells||pyp1-delta, nim1-delta, standard temp, micro|| ||pyp1 | cdc25 ||mitotic catastrophe||pyp1-delta, cdc25-OP, standard temp, micro|| ||pyp1 | cdc25 ||viable||pyp1-delta, cdc25-22, high temp, CGA, agar,|| ||pyp2 | cdc25 ||viable||pyp2-delta, cdc25-22, high temp, CGA, agar, yes|| ||pyp2 | cdc25 ||really elongated cells (30 um so high expressivity)||pyp2-OP, cdc25-22, standard temp, CGA, agar, yes|| [[BR]] ||1756736||http://curation.pombase.org/pombe/curs/1cf6a37d7872772f|| ||wis1 | wee1 ||wee||wis1-delta, wee1-50, high temp, micro|| ||wis1 | cdc2 ||normal length||wis1-delta, cdc2-1w, micro|| ||wis1 | cdc2 ||normal length||wis1-delta, cdc2-3w, micro|| ||wis1 | ppa1 ||elongated viable cells||wis1-delta, ppa1-delta, micro|| ||wis1 | ppa2 ||elongated viable cells||wis1-delta, ppa2-delta, micro|| [[BR]] ||1435723||http://curation.pombase.org/pombe/curs/b5aa547b2e76978f|| ||byr2 | mat1pm||normal meiosis||ste8-mutant, matipm-OP, micro, occurs_in(diploid)|| ||byr2 | mat1pm||normal sporulation||ste8-mutant, matipm-OP, micro, occurs_in(diploid)|| [[BR]] ||23115244||http://curation.pombase.org/pombe/curs/1f78fe7de80af20c|| ||fep1 | fxn1 (frataxin) ||increased RNA level during veg growth||deletion, northern, assayed_using(fio1), yes|| ||fep1 | fxn1 ||increased RNA level during veg growth||deletion, northern, assayed_using(str3), yes|| ||fep1 | fxn1 ||decreased RNA level during veg growth||deletion, northern, assayed_using(pcl1), yes|| ||fep1 | fxn1 ||increased RNA level during iron ion starvation||deletion, northern, assayed_using(fio1), yes|| ||fep1 | fxn1 ||increased RNA level during iron ion starvation||deletion, northern, assayed_using(str3), yes|| ||fep1 | fxn1 ||increased RNA level during iron ion starvation||deletion, northern, assayed_using(pcl1), yes|| ||fep1 | fxn1 ||decreased hypox cell growth on glucose||deletion, cga, yes, plates|| ||fep1 | fxn1 ||inviable on aerobic glucose||deletion, cga, yes, plates|| ||php4 | fxn1 ||decreased growth on aerobic glucose||deletion, cga, yes, plates|| ||php4 | fxn1 ||decreased growth on aerobic glucose||deletion, cga, yes, liquid|| ||php4 | fxn1 ||sensitive to iron ion starvation||deletion, cga, yes, plates|| ||php4 | fxn1 ||increased RNA level during veg growth||deletion, northern, assayed_using(pcl1), yes|| ||php4 | fxn1 ||increased RNA level during iron ion starv||deletion, northern, assayed_using(pcl1), yes|| ||php4 | fxn1 ||increased RNA level during veg growth||deletion, northern, assayed_using(isa1), yes|| ||php4 | fxn1 ||increased RNA level during iron ion starv||deletion, northern, assayed_using(isa1), yes|| ||php4 | fxn1 ||increased RNA level during veg growth||deletion, northern, assayed_using(fio1), yes|| ||php4 | fxn1 ||increased RNA level during iron ion starv||deletion, northern, assayed_using(fio1), yes|| ||php4 | fxn1 ||increased RNA level during veg growth||deletion, northern, assayed_using(str3), yes|| ||php4 | fxn1 ||increased RNA level during iron ion starv||deletion, northern, assayed_using(str3), yes|| ||grx4 | fxn1 ||decreased RNA level during veg growth||deletion, northern, assayed_using(pcl1), yes|| ||grx4 | fxn1 ||increased RNA level during veg growth||deletion, northern, assayed_using(fio1), yes|| [[BR]] ||1855255||http://curation.pombase.org/pombe/curs/e113c7320f53efc5|| ||pim1 | cdc2||cell cycle arrest in mitotic G2||cdc2-33, pim1-46, micro|| ||pim1 | cdc13||cell cycle arrest in mitotic G2||cdc13-117, pim1-46, micro|| ||pim1 | spi1||inviable spore||pim1-delta, spi1-op, cga|| ||pim1 | spi1||viable||pim1-46, spi1-op, cga|| [[BR]] ||1846086||http://curation.pombase.org/pombe/curs/c93df2f114eaee6e|| ||sds22 | sds23||viable vegetative cells||sds22-delta, sds23-OP, emm|| ||sds22 | sds21||viable vegetative cells||sds22-delta, sds21-OP, emm|| ||sds22 | sds21 | dis2||inviable spore||sds22-OP, sds21-delta, dis2-delta|| ||dis2 | sds21||viable vegetative cells||sds21-delta, dis2-OP, || ||dis2 | sds21||viable vegetative||sds21-OP, dis2-delta,|| ||dis2 | sds21||inviable||sds21-delta, dis2-delta,|| ||dis2 | sds22||viable vegetative cells||sds22-OP, dis2-cs,|| [[BR]] ||3042386||http://curation.pombase.org/pombe/curs/a64b97197e845b5b|| ||ras1 | mat1-M||normal sporulation||cga, ras1-delta, mat1-M-OP|| ||ras1 | mat1-P||normal sporulation||cga, ras1-delta, mat1-P-OP|| ||ras1 | byr1||normal sporulation||micro, diploid cells, ras1-delta, byr1-OP|| ||ras1 | byr1||abolished conjugation||micro, ras1-delta, byr1-OP|| ||ras1 | byr1||abnormal morphology||micro, ras1-delta, byr1-OP|| ||ras1 | byr1||elongated conjugation tubes (shmoo)||micro, ras1-G17V, byr1-OP|| ||ras1 | byr1||sterile||micro, ras1-OP, byr1-delta|| [[BR]] ||3034608||http://curation.pombase.org/pombe/curs/93c0ecbe5a58d0fe|| ||mei2 | mei3||viable vegetative cells||mei3-OP, mei2.16, CGA|| ||3357510||http://curation.pombase.org/pombe/curs/b2b393b33cecb3fd|| ||mei3| ran1 ||sporulation in haploid||both OP CGA|| [[BR]] ||6090122||http://curation.pombase.org/pombe/curs/b2369c57c9545f6d|| ||top1 | end1 ||decreased DNA topoisomerase activity||top1-710, end1-458 enzyme assay|| ||top1 | end1 ||decreased endodeoxyribonuclease activity||top1-710, end1-458 enzyme assay|| ||top1 | end1 ||viable vegetative cells||top1-710, end1-458 cga|| ||top1 | top2 ||abnormal chromatin organization during vegetative growth||strain 3421 unknown microscopy high temp|| ||top1 | top2 ||inviable high temp||strain 3421 unknown CGA high temp|| [[BR]] ||9135083||http://curation.pombase.org/pombe/curs/6ff4c9edff12167b|| ||wee1 | atf1 ||normal cell cycle arrest in mitotic G1 phase during nitrogen starvation||wee1-50, gad7::ura4, flow cytometry|| ||wee1 | atf1 ||decreased conjugation||wee1-50, gad7::ura4, CGA|| ||wee1 | atf1 ||decreased RNA level during nitrogen starvation||wee1-50, gad7::ura4, transcript expr, annotation_extension=assayed_using(PomBase:SPBC32C12.02)|| [[BR]] ||15347659||http://curation.pombase.org/pombe/curs/4395e90f8fc7e6d8|| ||cds1 | mad2 ||sensitive to HU||both deletion, cga yes 30 agar|| ||cds1 | mad2 ||normal growth during UV rad||both deletion, cga yes 30 agar|| ||cds1 | mad2 ||sensitive to MMS||both deletion, cga yes 30|| [[BR]] ||22910366||http://curation.pombase.org/pombe/curs/8ffe6ded62ad4ebc|| ||msy1 | msy2 || sensitive to sorbitol||both deleted, cga, yes|| ||msy1 | msy2 || sensitive to high osmolarity ||both deleted, cga, yes|| ||msy1 | msy2 || sensitive to sorbitol||both deleted, microscopy, emm|| ||msy1 | msy2 || sensitive to high osmolarity ||both deleted, microscopy, emm|| ||msy1 | msy2 || normal growth on sorbitol/normal viability high osmolarity||msy2 delted, msy1-OP, cga, emm|| ||msy1 | msy2 || normal growth on sorbitol/normal viability high osmolarity||msy1 delted, msy2-OP, cga, emm|| ||msy1 | msy2 ||sensitive to hypoosmotic conditions||deletion, cga|| ||msy1 | msy2 ||sensitive to hypoosmotic conditions||deletion, microscopy, emm|| ||msy1 | msy2 ||sensitive to calcium during cellular hypotonic response||deletion, cga|| ||msy1 | msy2 ||sensitive to calcium during cellular hypotonic response||msy2-deletion, msy1-D556A,D558A,E566A,E567A cga|| ||msy1 | msy2 ||normal growth on calcium during cellular hypotonic response||msy1-deletion, msy2-D405A,D407A,D415A,E416A cga|| [[BR]] ||12553909||http://curation.pombase.org/pombe/curs/20b51f83ef3dce69/|| ||int6 | rpn12||inviable cell population||int6-delta, rpn12-1, cga, yes, agar, standard temp|| ||int6 | rpn12||decreased cell population growth||int6-delta, rpn12-1, cga, yes, agar, low temp|| ||int6 | rpt2||decreased cell population growth||int6-delta, rpt2-1, cga, yes, agar, standard temp|| ||rpn501 | rpn502||normal cell growth||both OP, agar, standard temp, cga|| ||rpn501 | rpn502||normal cell growth on TPCK||both OP, agar, EMM, standard temp, cga|| ||int6 | rpn12||decreased cell population growth||int6-OP, rpn12-1, cga, emm, agar, high temp|| ||int6 | rpn12||normal cell population growth||int6-OP, rpn12-1, cga, emm, agar, standard temp|| ||int6 | rpn12||mitotic cell cycle arrest in metaphase||int6-delta, rpn12-1, microscopy, yes, standard temp|| ||int6 | rpn12||short spindle||int6-delta, rpn12-1, microscopy, yes, standard temp|| ||int6 | rpn12||cut||int6-delta, rpn12-1, microscopy, yes, standard temp|| ||rpn501 | rpn502||sensitive to cold||both deleted, agar, low temp, YES, cga|| ||rpn501 | rpn502||sensitive to canavanine||both deleted, agar, low temp, YES, cga|| ||rpn501 | rpn502||normal protein localization to nucleus||both deleted, microscopy, assayed using int6|| ||cut8 | int6||viable cell pop at low temp||int6-delta, cut8-653, cga, yes, agar|| ||cut8 | int6||inviable cell pop at normal temp||int6-delta, cut8-653, cga, yes, agar|| ||cut8 | int6||inviable cell pop at high temp||int6-delta, cut8-653, cga, yes, agar|| [[BR]] ||17189249||http://curation.pombase.org/pombe/curs/6d2d5b10bcbc0a55|| ||chk1 | cds1 ||sensitive to HU||both deleted, CGA, agar, standard temp, emm, thiamine added|| ||chk1 | tel2 ||sensitive to HU||tel2 knockdown, chk1 deleted, CGA, agar, standard temp, emm, thiamine added|| ||tel2 | cds1 ||sensitive to HU||tel2 knockdown, cds1 deleted, CGA, agar, standard temp, emm, thiamine added|| ||chk1 | cds1 ||sensitive to UV||both deleted, CGA, agar, standard temp, emm, thiamine added|| ||chk1 | tel2 ||sensitive to UV||tel2 knockdown, chk1 deleted, CGA, agar, standard temp, emm, thiamine added|| ||tel2 | cds1 ||normal cell cycle regulation during cellular response to hydroxyurea ||tel2-knockdown, cds1 deleted,microscopy|| ||tel2 | chk1 ||cut during cellular response to hydroxyurea ||tel2-knockdown, chk1 deleted,microscopy|| ||tel2 | swi1 ||inviable vegetative cells||tel2-knockdown, swi1-delta, CGA, emm, thiamine added|| ||tel2 | swi1 ||accumulation of rad22 foci||tel2-knockdown, swi1-delta, microscopy|| ||tel2 | swi1 ||accumulation of double-strand break sites ||tel2-knockdown, swi1-delta, microscopy|| [[BR]] ||8290359||http://curation.pombase.org/pombe/curs/d8499d610fc61689|| ||rad8 | rad13 ||sensitive to UV||both deleted, cga|| ||rad8 | rad9 ||sensitive to UV||both deleted, cga|| ||rad8 | rad21 ||sensitive to UV||both deleted, cga|| ||rad8 | smc6 ||sensitive to UV||both deleted, cga|| [[BR]] ||12724426||http://curation.pombase.org/pombe/curs/55c12e425ccc4499|| ||top3 | rqh1 ||viable vegetative cells||top3-delta, rqh1-hus2-22 cga, yes, agar, 30|| ||top3 | rqh1 ||viable vegetative cells||top3-delta, rqh1-K/I cga, yes, agar, 30|| ||top3 | rqh1 ||viable vegetative cells||top3-delta, rqh1-rad12-502 cga, yes, agar, 30|| ||top3 | rqh1 ||viable vegetative cells||top3-delta, rqh1-K/R cga, yes, agar, 30|| ||top3 | rqh1 ||viable vegetative cells||top3-delta, rqh1-K/A cga, yes, agar, 30|| ||top3 | rqh1 ||viable vegetative cells||top3-Y330F(OP), wildtype protein in background, rqh1-delta cga, yes, agar, 30|| ||top3 | rqh1 ||normal cell morphology||top3-Y330F(OP), wildtype protein in background, rqh1-delta microscopy|| ||top3 | rqh1 ||sensitive to gamma irradiation||top3-delta, rqh1-delta cga|| ||top3 | rqh1 ||sensitive to gamma irradiation||top3-delta, rqh1-rad12-502 cga|| ||top3 | rqh1 ||sensitive to UV||top3-delta, rqh1-rad12-502 cga|| ||top3 | rqh1 ||sensitive to UV||top3-delta, rqh1-delta cga|| ||top3 | rqh1 ||decreased protein level||top3-delta, rqh1-rad12-502 western, assayed_using(rqh1)|| ||rad3 | rqh1 ||inviable cell population||rad3-delta, rqh1-delta cga|| ||rad3 | top3 ||inviable cell population||rad3-delta, top3-delta cga|| ||rad3 | top3 | rqh1 ||inviable cell population||rad3-delta, top3-delta, rqh1-delta cga|| ||rad26 | rqh1 ||inviable cell population||rad26-delta, rqh1-delta cga|| ||rad26 | top3 ||inviable cell population||rad26-delta, top3-delta cga|| ||rad26 | top3 | rqh1 ||inviable cell population||rad26-delta, top3-delta, rqh1-delta cga|| ||rad1 | top3 ||inviable cell population||rad1-delta, top3-delta cga|| ||cds1 | top3 ||inviable cell population||cds1-delta, top3-delta cga|| ||rhp18 | top3 ||inviable cell population||rhp18-delta, top3-delta cga|| ||uve1 | top3 ||inviable cell population||uve1-delta, top3-delta cga|| ||rad1 | rqh1 ||normal cell population growth||rad1-delta, rqh1-delta cga|| ||rad1 | top3 | rqh1 ||normal cell population growth||rad1-delta, top3-delta, rqh1-delta cga|| ||rad1 | rqh1 ||viable vegetative cell||rad1-delta, rqh1-delta cga|| ||rad1 | top3 | rqh1 ||viable vegetative cell||rad1-delta, top3-delta, rqh1-delta cga|| ||cds1 | rqh1 ||normal cell population growth||cds1-delta, rqh1-delta cga|| ||cds1 | top3 | rqh1 ||normal cell population growth||cds1-delta, top3-delta, rqh1-delta cga|| ||cds1 | rqh1 ||viable vegetative cell||cds1-delta, rqh1-delta cga|| ||cds1 | top3 | rqh1 ||viable vegetative cell||cds1-delta, top3-delta, rqh1-delta cga|| ||rhp51 | rqh1 ||normal cell population growth||rhp51-delta, rqh1-delta cga|| ||rhp51 | top3 ||normal cell population growth||rhp51-delta, top3-delta cga|| ||rhp51 | top3 | rqh1 ||normal cell population growth||rhp51-delta, top3-delta, rqh1-delta cga|| ||rhp51 | rqh1 ||viable vegetative cell||rhp51-delta, rqh1-delta cga|| ||rhp51 | top3 ||viable vegetative cell||rhp51-delta, top3-delta cga|| ||rhp51 | top3 | rqh1 ||viable vegetative cell||rhp51-delta, top3-delta, rqh1-delta cga|| ||rhp54 | rqh1 ||normal cell population growth||rhp54-delta, rqh1-delta cga|| ||rhp54 | top3 ||normal cell population growth||rhp54-delta, top3-delta cga|| ||rhp54 | top3 | rqh1 ||normal cell population growth||rhp54-delta, top3-delta, rqh1-delta cga|| ||rhp54 | rqh1 ||viable vegetative cell||rhp54-delta, rqh1-delta cga|| ||rhp54 | top3 ||viable vegetative cell||rhp54-delta, top3-delta cga|| ||rhp54 | top3 | rqh1 ||viable vegetative cell||rhp54-delta, top3-delta, rqh1-delta cga|| ||rhp55 | rqh1 ||normal cell population growth||rhp55-delta, rqh1-delta cga|| ||rhp55 | top3 ||normal cell population growth||rhp55-delta, top3-delta cga|| ||rhp55 | top3 | rqh1 ||normal cell population growth||rhp55-delta, top3-delta, rqh1-delta cga|| ||rhp55 | rqh1 ||viable vegetative cell||rhp55-delta, rqh1-delta cga|| ||rhp55 | top3 ||viable vegetative cell||rhp55-delta, top3-delta cga|| ||rhp55 | top3 | rqh1 ||viable vegetative cell||rhp55-delta, top3-delta, rqh1-delta cga|| ||rhp18 | rqh1 ||normal cell population growth||rhp18-delta, rqh1-delta cga|| ||rhp18 | top3 | rqh1 ||normal cell population growth||rhp18-delta, top3-delta, rqh1-delta cga|| ||rhp18 | rqh1 ||viable vegetative cell||rhp18-delta, rqh1-delta cga|| ||rhp18 | top3 | rqh1 ||viable vegetative cell||rhp18-delta, top3-delta, rqh1-delta cga|| ||uve1 | rqh1 ||normal cell population growth||uve1-delta, rqh1-delta cga|| ||uve1 | top3 | rqh1 ||normal cell population growth||uve1-delta, top3-delta, rqh1-delta cga|| ||uve1 | rqh1 ||viable vegetative cell||uve1-delta, rqh1-delta cga|| ||uve1 | top3 | rqh1 ||viable vegetative cell||uve1-delta, top3-delta, rqh1-delta cga|| ||rad22 | rqh1 ||decreased cell growth||rad22-delta, rqh1-delta cga|| ||rad22 | top3 ||decreased cell growth||rad22-delta, top3-delta cga|| ||rad22 | top3 | rqh1 ||normal cell population growth||rad22-delta, top3-delta, rqh1-delta cga|| ||rad22 | rqh1 ||viable vegetative cell||rad22-delta, rqh1-delta cga|| ||rad22 | top3 ||viable vegetative cell||rad22-delta, top3-delta cga|| ||rad22 | top3 | rqh1 ||viable vegetative cell||rad22-delta, top3-delta, rqh1-delta cga|| ||rhp51 | top3||viable vegetative cell||rhp51-delta, top3-Y330F OP, cga|| ||rhp54 | top3||viable vegetative cell||rhp54-delta, top3-Y330F OP, cga|| ||rhp55 | top3||viable vegetative cell||rhp55-delta, top3-Y330F OP, cga|| ||rad22 | top3||viable vegetative cell||rad22-delta, top3-Y330F OP, cga|| ||rhp51 | top3||viable cell population||rhp51-delta, top3-Y330F OP, cga|| ||rhp54 | top3||viable cell population||rhp54-delta, top3-Y330F OP, cga|| ||rhp55 | top3||viable cell population||rhp55-delta, top3-Y330F OP, cga|| ||rad22 | top3||viable cell population||rad22-delta, top3-Y330F OP, cga|| ||rhp51 | rqh1 ||sensitive to UV||all deleted, cga, agar|| ||rhp51 | top3 ||sensitive to UV||all deleted, cga, agar|| ||rhp51 | top3 | rqh1 ||sensitive to UV||all deleted, cga, agar|| ||rhp54 | rqh1 ||sensitive to UV||all deleted, cga, agar|| ||rhp54 | top3 ||sensitive to UV||all deleted, cga, agar|| ||rhp54 | top3 | rqh1 ||sensitive to UV||all deleted, cga, agar|| ||rad22 | rqh1 ||sensitive to UV||all deleted, cga, agar|| ||rad22 | top3 ||sensitive to UV||all deleted, cga, agar|| ||rad22 | top3 | rqh1 ||sensitive to UV||all deleted, cga, agar|| ||rhp55 | top3 | rqh1 ||sensitive to UV||all deleted, cga, agar|| ||rhp51 | top3 ||sensitive to gamma irradiation||all deleted, cga|| ||rhp51 | rqh1 ||sensitive to gamma irradiation||all deleted, cga|| ||rhp51 | top3 | rqh1 ||sensitive to gamma irradiation||all deleted, cga|| [[BR]] ||12931193||http://curation.pombase.org/pombe/curs/747342ebb6e04e9d|| ||ppb1 | rnc1 ||normal veg cell growth on glucose carbon source||cga, ppb1-delta, rnc1-OP, agar, standard temp|| ||ppb1 | pmp1 ||normal veg cell growth on glucose carbon source||cga, ppb1-delta, pmp1-OP, agar, standard temp|| ||ppb1 | pek1 ||normal veg cell growth on glucose carbon source||cga, ppb1-delta, pek1-OP, agar, standard temp|| ||ppb1 | rnc1 ||normal cell population growth during cellular response to salt stress||cga, ppb1-delta, rnc1-OP, agar, standard temp, mgcl2 added|| ||ppb1 | pmp1 ||normal cell population growth during cellular response to salt stress||cga, ppb1-delta, pmp1-OP, agar, standard temp, mgcl2 added|| ||ppb1 | pek1 ||normal veg cell growth on glucose carbon source||cga, ppb1-delta, pek1A(T238A)-OP, agar, YPD|| ||ppb1 | rnc1 | pmp1 ||normal veg cell growth on glucose carbon source||cga, ppb1-delta, rnc1-delta, pmp1-OP, agar, YPD|| ||ppb1 | rnc1 | pek1 ||normal veg cell growth on glucose carbon source||cga, ppb1-delta, rnc1-delta, pek1-OP, agar, YPD|| ||ppb1 | rnc1 | pek1 ||normal veg cell growth on glucose carbon source||cga, ppb1-delta, rnc1-delta, pek1A(T238A)-OP, agar, YPD|| ||ppb1 | rnc1 ||sensitive to salt stress||cga, ppb1-delta, rnc1-delta, agar, YPD, mgcl2 added|| ||ppb1 | rnc1 | pmp1 ||sensitive to salt stress||cga, ppb1-delta, rnc1-delta, pmp1-OP, agar, YPD, mgcl2 added|| ||ppb1 | rnc1 | pek1 ||normal cell population growth during cellular response to salt stress||cga, ppb1-delta, rnc1-delta, pek1A(T238A)-OP, agar, YPD, mgcl2 added|| ||pmp1 | pek1 ||normal cell population growth on tacrolimus during salt stress||cga, pmp1-delta, pek1-OP, agar, YPD, mgcl2 added| ||ppb1 | rnc1 ||sensitive to salt stress||cga, ppb1-delta, rnc1-G110D-OP, agar, YPD, mgcl2 added|| ||ppb1 | rnc1 ||sensitive to salt stress||cga, ppb1-delta, rnc1-G195D-OP, agar, YPD, mgcl2 added|| ||ppb1 | rnc1 ||sensitive to salt stress||cga, ppb1-delta, rnc1-G337D-OP, agar, YPD, mgcl2 added|| ||ppb1 | pmp1 ||sensitive to salt stress||cga, ppb1-delta, pmp1-M2, agar, YPD, mgcl2 added|| ||ppb1 | pmp1 ||sensitive to salt stress||cga, ppb1-delta, pmp1-M12, agar, YPD, mgcl2 added|| ||ppb1 | pmp1 ||sensitive to salt stress||cga, ppb1-delta, pmp1-M23, agar, YPD, mgcl2 added|| ||ppb1 | pmp1 ||sensitive to salt stress||cga, ppb1-delta, pmp1-M123, agar, YPD, mgcl2 added|| ||ppb1 | pmp1 | rnc1 ||sensitive to salt stress||cga, ppb1-delta, pmp1-M123, rnc1-op agar, YPD, mgcl2 added|| ||ppb1 | rnc1 ||sensitive to salt stress||cga, ppb1-delta, rnc1-T50A, agar, YPD, mgcl2 added|| ||ppb1 | rnc1 ||normal cell population growth during cellular response to salt stress||cga, ppb1-delta, rnc1-T171A, agar, YPD, mgcl2 added|| ||ppb1 | rnc1 ||normal cell population growth during cellular response to salt stress||cga, ppb1-delta, rnc1-T171A, agar, YPD, mgcl2 added|| ||ppb1 | rnc1 ||normal cell population growth during cellular response to salt stress||cga, ppb1-delta, rnc1-TT177A, agar, YPD, mgcl2 added|| ||ppb1 | rnc1 ||normal cell population growth during cellular response to salt stress||cga, ppb1-delta, rnc1-S278A, agar, YPD, mgcl2 added|| ||ppb1 | rnc1 ||normal cell population growth during cellular response to salt stress||cga, ppb1-delta, rnc1-S283A, agar, YPD, mgcl2 added|| ||ppb1 | rnc1 ||normal cell population growth during cellular response to salt stress||cga, ppb1-delta, rnc1-T45A, agar, YPD, mgcl2 added|| ||ppb1 | rnc1 ||resistant to salt stress||cga, ppb1-delta, rnc1-T50D, agar, YPD, mgcl2 added|| ||ppb1 | rnc1 ||resistant to salt stress||cga, ppb1-delta, rnc1-T50E, agar, YPD, mgcl2 added|| [[BR]] ||10504305||http://curation.pombase.org/pombe/curs/e0e85df0e0e16a77|| ||pck1 | pck2||decreased 1,3-beta-D-glucan synthase activity||pck1-deletion, pck2-kd enzyme assay|| ||pck1 | pck2||decreased 1,3-beta-D-glucan synthase activity||pck1-kd, pck2-deletion enzyme assay|| ||pck1 | pck2||shrunken inviable septate cells||pck1-kd, pck2-deletion enzyme assay|| ||pck1 | pck2||shrunken inviable septate cells||pck1-delta, pck2-kd cga || ||pck1 | pck2||shrunken inviable septate cells||pck1-delta, pck2-kd cga sorbitol added|| ||pck1 | pck2||sensitive to papulacandin||pck1-kd, pck2-op cga agar standard temp|| ||pck1 | pck2||sensitive to calcofluor||pck1-kd, pck2-op cga agar standard temp|| ||pck1 | pck2||sensitive to echinocandin||pck1-kd, pck2-op cga agar standard temp|| ||pck1 | cps1||sensitive to calcofluor||pck1-kd, cps1-op cga agar standard temp|| ||pck1 | gls2||sensitive to calcofluor||pck1-kd, gls2-op cga agar standard temp|| [[BR]] ||22748672||http://curation.pombase.org/pombe/curs/6eecc9d84084dc5c|| ||pnk1 | pku70||sensitive to ionizing radiation||both deleted, cga, yes|| ||pnk1 | rad51||sensitive to ionizing radiation||both deleted, cga, yes|| ||pnk1 | apn2||inviable after spore germination, multiple cell divisions, elongated & branched cells||both deleted, microscopy|| ||pnk1 | apn2 | nth1||decreased cell growth on glucose||all deleted, cga|| ||pnk1 | apn2 | tdp1||decreased cell growth on glucose||all deleted, cga|| ||pnk1 | apn2 | nth1||elongated branched cells ||all deleted, micro|| ||pnk1 | apn2 | tdp1||elongated branched cells||all deleted, micro|| ||nth1 | apn2||normal cell population growth on glucose carbon source ||all deleted, cga, yes, agar, 30|| ||nth1 | tdp1||normal cell population growth on glucose carbon source ||all deleted, cga, yes, agar, 30|| ||tdp1 | apn2||normal cell population growth on glucose carbon source ||all deleted, cga, yes, agar, 30|| ||tdp1 | pnk1||normal cell population growth on glucose carbon source ||all deleted, cga, yes, agar, 30|| ||nth1 | pnk1||normal cell population growth on glucose carbon source ||all deleted, cga, yes, agar, 30|| ||nth1 | apn2||sensitive to MMS ||all deleted, cga, yes, agar, 30|| ||nth1 | tdp1||sensitive to MMS ||all deleted, cga, yes, agar, 30|| ||tdp1 | apn2||sensitive to MMS ||all deleted, cga, yes, agar, 30|| ||tdp1 | pnk1||sensitive to MMS ||all deleted, cga, yes, agar, 30|| ||nth1 | pnk1||sensitive to MMS ||all deleted, cga, yes, agar, 30|| [[BR]] ||23658229||http://curation.pombase.org/pombe/curs/bdc65ab8c484c62c/|| ||red5 | sme2||decreased sporulation||red5-2, sme2-delta mciroscopy|| [[BR]] ||22592553||http://curation.pombase.org/pombe/curs/fa1b6031c1a25b19|| ||spcc1450.16c | spac1786.01c||increased cellular triglyceride level||subst quant, deletion, emm, stationary phase|| ||spac1786.01c | spac1a6.05c||increased cellular triglyceride level||subst quant, deletion, emm, stationary phase|| ||spcc1450.16c | spac1786.01c | spac1a6.05c||increased cellular triglyceride level||subst quant, deletion, emm, stationary phase|| ||spcc1450.16c | spac1786.01c | spac1a6.05c||increased cellular triglyceride level||microscopy, deletion, stationary phase|| ||spcc1450.16c | spac1786.01c | spac1a6.05c||normal cellular sterol ester level||subst quant, deletion, stationary phase|| ||spcc1450.16c | spac1786.01c | spac1a6.05c||sensitive to cerulenin||cga, deletion, liquid emm 30|| ||spcc1450.16c | spac1786.01c | spac1a6.05c||normal growth on cerulenin||cga, deletion, oleic acid added, liquid emm 30|| ||spcc1450.16c | spac1786.01c ||sensitive to cerulenin||cga, deletion, liquid emm 30|| ||spcc1450.16c | spac1a6.05c||sensitive to cerulenin||cga, deletion, liquid emm 30|| ||spac1786.01c | spac1a6.05c||sensitive to cerulenin||cga, deletion, liquid emm 30|| [[BR]] ||12686557||http://curation.pombase.org/pombe/curs/197fff91f52f0f50|| ||gda1 | ynd1||inviable germinating spore 1-4 cell divisions||cga dbl deletion yes|| [[BR]] ||23145048||http://curation.pombase.org/pombe/curs/9abb48d4dd839d0a|| ||erg31 | erg32||normal cellular squalene level||deletion, subst quant|| ||erg31 | erg32||decreased cellular lanesterol level||deletion, subst quant|| ||erg31 | erg32||decreased cellular ergosterol level||deletion, subst quant|| ||erg31 | erg32||viable veg cell||deletion, cga, ypd, agar, stand temp|| ||erg31 | erg32||normal cell population growth on glucose carbon source||deletion, cga, ypd, agar, stand temp|| ||erg31 | erg32||normal growth on pravastatin||deletion, cga, ypd, stand temp|| ||erg31 | erg32||normal growth at high temp||deletion, cga, ypd|| ||erg31 | erg32||viable cell high temp||deletion, cga, ypd,|| [[BR]] ||12963726||http://curation.pombase.org/pombe/curs/4781b51189a37d78|| ||plh1 | dga1|| FYPO:0002195 normal morphology viable vegetative cell population ||cga dbl deletion, all combinations of glucose MM, YES, low, stand, hi temp|| ||plh1 | dga1|| viable veg cell at hi temp ||cga dbl deletion, glucose MM & YES, || ||plh1 | dga1|| viable veg cell at low temp ||cga dbl deletion, glucose MM & YES, || ||plh1 | dga1|| viable veg cell ||cga dbl deletion, standard temp, glucose MM, YES, || ||plh1 | dga1|| TAG absent from cell ||subst quant both delted || [[BR]] ||23051734||http://curation.pombase.org/pombe/curs/1a58c3ee1e7be06d|| ||myo51 | myo52||dispersed actin cortical patch localization||myoV-delta, deletion, microsopy, || ||myo51 | myo52||pear-shaped during veg growth||deletion, microsopy|| ||myo51 | myo52||short, misoriented, actin cable bundles ||deletion, microsopy, || ||myo51 | myo52||decreased rate of actin cable retrograde flow||deletion, microsopy|| ||myo51 | myo52||normal protein localization to cell tip||deletion-51, tailless-52, assayed_using(myo52)|| ||myo51 | myo52||normal protein localization to cell tip||both deleted, assayed_using(bud6, pob1, tea4, cdc42, tip1)|| ||myo51 | myo52||short, misoriented, actin cable bundles ||51-deletion, 52-delta-tail, microsopy, || ||myo51 | myo52||decreased rate of actin cable retrograde flow||51-deletion, 52-delta-tail, microsopy, || ||myo51 | ypt3||short, misoriented, actin cable bundles||deletion-51, ypt3-i5, microsopy,stand temp|| ||myo51 | ypt3||loss of cytoplasmic foci||deletion-51, ypt3-i5, microsopy, stand temp, assayed_using(myo52)|| ||myo51 | ypt3||normal protein localization to cell tip||deletion-51, ypt3-i5, microsopy, stand temp, assayed_using(myo52)|| [[BR]] ||||http://curation.pombase.org/pombe/curs/d445419299dddade|| ||swi6 | mis4||decreased protein localization to heterochromatin during vegetative growth||deletion, unknown, microscopy, assayed_using(rad21)|| ||eso1 | wpl1||normal protein localization to telomeric region/heterochromatin||deletion, deletion, CHIP, assayed_using(rad21)|| ||eso1 | wpl1||normal protein localization to peri-centromeric region/heterochromatin||deletion, deletion, CHIP, assayed_using(rad21)|| ||eso1 | wpl1||increased protein localization to rDNA||deletion, deletion, CHIP, assayed_using(rad21)|| ||eso1 | wpl1||viable cell pop following spore germination||deletion, deletion, cga|| ||eso1 | wpl1||normal minichromosome loss||deletion, deletion, loss exp|| ||wpl1 | psm3||normal veg cell pop growth||deletion, K105R, cga, agar, yes, endogenous expr, standard temp|| ||wpl1 | psm3||normal veg cell pop growth||deletion, K106R, cga, agar, yes, endogenous expr, standard temp|| ||wpl1 | psm3||normal veg cell pop growth||deletion, K105R,K106R cga, agar, yes, endogenous expr, standard temp|| ||wpl1 | psm3||normal veg cell pop growth hi temp||deletion, K105R, cga, agar, yes, endogenous expr, || ||wpl1 | psm3||normal veg cell pop growth hi temp||deletion, K106R, cga, agar, yes, endogenous expr, || ||wpl1 | psm3||normal veg cell pop growth hi temp||deletion, K105R, K106R cga, agar, yes, endogenous expr, || ||wpl1 | eso1||normal veg cell population growth||deletion, deletion, cga, agar, yes, standard temp|| ||psm3 | wpl1 |eso1||normal veg cell population growth||K105N, deletion, deletion, cga, agar, yes, standard temp|| ||psm3 | wpl1 |eso1||normal veg cell population growth||K106N, deletion, deletion, cga, agar, yes, standard temp|| ||psm3 | wpl1 |eso1||normal veg cell population growth||K105N, K106N, deletion, deletion, cga, agar, yes, standard temp|| ||psm3 | eso1||normal veg cell population growth||K105N,K106N, deletion, cga, agar, yes, standard temp|| ||psm3 | eso1||decreased veg cell population growth||K105N, deletion, cga, agar, yes, standard temp|| ||psm3 | eso1||decreased veg cell population growth||K106N, deletion, cga, agar, yes, standard temp|| ||psm3 | eso1||normal veg cell pop growth||K105R,K106R, eso1-H17, cga, agar, yes, standard temp|| ||psm3 | eso1 | wpl1||normal veg cell pop growth||K105R,K106R, eso1-H17, deletion, cga, agar, yes, standard temp|| ||wpl1 | eso1||normal veg cell population growth hi temp||deletion, deletion, cga, agar, yes|| ||psm3 | wpl1 |eso1||normal veg cell population growth hi temp||K105N, deletion, deletion, cga, agar, yes|| ||psm3 | wpl1 |eso1||normal veg cell population growth hi temp||K106N, deletion, deletion, cga, agar, yes|| ||psm3 | wpl1 |eso1||normal veg cell population growth hi temp||K105N, K106N, deletion, deletion, cga, agar, yes|| ||psm3 | eso1||normal veg cell population growth hi temp||K105N,K106N, deletion, cga, agar, yes, standard temp|| ||psm3 | eso1||decreased veg cell population growth hi temp||K105N, deletion, cga, agar, yes|| ||psm3 | eso1||decreased veg cell population growth hi temp||K106N, deletion, cga, agar, yes|| ||psm3 | eso1||inviable veg cell pop at high temp||K105R,K106R, eso1-H17, cga, agar, yes|| ||eso1 | psm3||inviable spore||deletion, K105R, cga, agar, yes, standadr temp, endogenous expr, || ||eso1 | wpl1||normal minichromosome loss||deletion, deletion, other|| ||eso1 | wpl1 | psm3 ||normal minichromosome loss||deletion, deletion, K105N, other|| ||eso1 | wpl1 | psm3 ||normal minichromosome loss||deletion, deletion, K106N, other|| ||eso1 | wpl1 | psm3 ||normal minichromosome loss||deletion, deletion, K105N, K106N, other|| ||wpl1 | psm3||normal minichromosome loss||deletion, K105N, K106N, other|| ||wpl1 | psm3||normal minichromosome loss||deletion, K105R, other|| ||wpl1 | psm3||normal minichromosome loss||deletion, K106R, other|| ||wpl1 | psm3||normal minichromosome loss||deletion, K105R, K106R, other|| ||eso1 | psm3||increased minichromosome loss||deletion, K105N, K106N, other|| ||wpl1 | psm3||normal protein localization to pericentromeric region||deletion, K105N, K106N, CHIP, assayed_using(rad21)||? ||wpl1 | psm3||decreased maintenance of protein localization to pericentromeric region||deletion, K105N, K106N, CHIP, assayed_using(rad21)|| ||wpl1 | psm3||normal viability in stationary phase||deletion, psm3-RR CGA|| [[BR]] ||http://curation.pombase.org/pombe/curs/758c93b03dfe5c59|| ||pof3 | swi1||decreased protein degradation during vegetative growth||deletion, western, assayed_using(mcm4)|| ||pof3 | swi1||sensitive to cpt||deletion, cga, std temp yes agar|| ||pof3 | swi1||mitotic catastrophe with cut (this one is NOT elongated)||deletion, micro, std temp yes|| [[BR]] ||http://curation.pombase.org/pombe/curs/7415c70250f4c0b2|| ||wis4| win1 ||decreased protein phosphorylation during salt stress||win1-1, wis4-delta, western, assayed_using(sty1) KCl added|| ||wis4| win1 ||abolished protein phosphorylation during salt stress||Win1KM, Wis4KM, western, assayed_using(sty1) KCl added|| [[BR]] ||http://curation.pombase.org/pombe/curs/68ae1fabd9900b1b|| ||rad3| tel1 ||abolished H2A phosphorylation during IR||deletion, western|| ||rad3| mre11 ||abolished H2A phosphorylation during IR||deletion, western|| ||rad3| mre11 ||normal protein localisation to telomeres||deletion-rad3, mre11-W248R, gel electro assayed_using(tel1)|| ||rad3| mre11 ||normal protein localisation to telomeres||deletion-rad3, mre11-H134S, gel electro assayed_using(tel1)|| ||rad3| mre11 ||abolished protein localisation to telomeres||deletion-rad3, mre11-deletion, gel electro assayed_using(tel1)|| [[BR]] ||http://curation.pombase.org/pombe/curs/68ae1fabd9900b1b|| ||fml1| sfr1||increased occurrence of meiotic cross-overs||deletion, other|| ||mus81| sfr1||decreased occurrence of meiotic cross-overs||deletion, other|| ||mus81| sfr1||decreased sporulation||deletion, cga|| ||mus81| fml1||decreased sporulation||deletion, high penetrance, cga|| ||mus81| sfr1| fml1||decreased sporulation||deletion cga|| ||fml1| sfr1||decreased spore germination||deletion, sfr1-delta2, cga|| ||mus81| sfr1||decreased spore germination||deletion, sfr1-delta2, cga|| ||mus81| rec12| fml1||decreased spore germination||deletion, cga|| [[BR]] ||||http://curation.pombase.org/pombe/curs/0f9cbe164dbdc4a4|| ||erf2 | erf4||normal protein palmitoylation during veg growth||OP, western, annotation_extension=assayed_using(PomBase:ras1)|| ||erf2 | erf4||increased protein palmitoylation during veg growth||OP, western, annotation_extension=assayed_using(PomBase:rho3)|| ||pfa5 | akr1||normal protein palmitoylation during meiosis||deletion, western, annotation_extension=assayed_using(PomBase:SPAC17H9.09c)|| ||ran1 | erf2 | erf4 ||sporulation in haploid||pat1-114, OP, OP, standard temp, EMM || ||ran1 | erf2 | erf4 ||meiosis in haploid||pat1-114, OP, OP, standard temp, EMM || ||ran1 | erf2 | erf4 ||normal vegetative cell population growth||pat1-114, DHHA(C212A)-OP, OP, standard temp, EMM || ||ran1 | erf2 | erf4 | mei4 ||arrested cells with 1 nucleus and abnormal morphology||pat1-114, OP, OP, deletion, standard temp, EMM || [[BR]] ||http://curation.pombase.org/pombe/curs/83b3cec202522e28|| ||dcd1| brc1 ||mutator|| dbl deletion other||| ||dcd1| brc1 ||decreased cell population growth on glucose|| dbl deletion yes agar||| ||dcd1| brc1 ||sensitive to uv|| dbl deletion yes agar||| ||dcd1| brc1 ||sensitive to hu|| dbl deletion yes agar||| ||dcd1| brc1 ||sensitive to cpt|| dbl deletion yes agar||| ||dcd1| brc1 ||sensitive to mms|| dbl deletion yes agar||| ||dcd1| brc1 ||sensitive to 4nqo|| dbl deletion yes agar||| ||dcd1| brc1 ||sensitive to bleomycin|| dbl deletion yes agar||| ||dcd1| chk1 ||decreased cell population growth on glucose|| dbl deletion yes agar||| ||dcd1| chk1 ||sensitive to uv|| dbl deletion yes agar||| ||dcd1| chk1 ||sensitive to hu|| dbl deletion yes agar||| ||dcd1| chk1 ||sensitive to cpt|| dbl deletion yes agar||| ||dcd1| chk1 ||sensitive to mms|| dbl deletion yes agar||| ||dcd1| cds1 ||decreased cell population growth on glucose|| dbl deletion yes agar||| ||dcd1| cds1 ||sensitive to uv|| dbl deletion yes agar||| ||dcd1| cds1 ||sensitive to hu|| dbl deletion yes agar||| ||dcd1| cds1 ||sensitive to cpt|| dbl deletion yes agar||| ||dcd1| cds1 ||sensitive to mms|| dbl deletion yes agar||| ||dcd1| cds1 ||decreased cell population growth on glucose|| deletion, cds1-T8A yes agar||| ||dcd1| cds1 ||sensitive to uv|| deletion, cds1-T8A yes agar||| ||dcd1| cds1 ||sensitive to hu|| deletion, cds1-T8A yes agar||| ||dcd1| cds1 ||sensitive to cpt|| deletion, cds1-T8A yes agar||| ||dcd1| cds1 ||sensitive to mms|| deletion, cds1-T8A yes agar||| ||dcd1| ssb3 ||decreased cell population growth on glucose|| dbl deletion yes agar||| ||dcd1| ssb3 ||sensitive to uv|| dbl deletion yes agar||| ||dcd1| ssb3 ||sensitive to hu|| dbl deletion yes agar||| ||dcd1| ssb3 ||sensitive to cpt|| dbl deletion yes agar||| ||dcd1| ssb3 ||sensitive to mms|| dbl deletion yes agar||| ||dcd1| swi1 ||decreased cell population growth on glucose|| dbl deletion yes agar||| ||dcd1| swi1 ||sensitive to uv|| dbl deletion yes agar||| ||dcd1| swi1 ||sensitive to hu|| dbl deletion yes agar||| ||dcd1| swi1 ||sensitive to cpt|| dbl deletion yes agar||| ||dcd1| swi1 ||sensitive to mms|| dbl deletion yes agar||| ||dcd1| mus81 ||decreased cell population growth on glucose|| dbl deletion yes agar||| ||dcd1| mus81 ||sensitive to uv|| dbl deletion yes agar||| ||dcd1| mus81 ||sensitive to hu|| dbl deletion yes agar||| ||dcd1| mus81 ||sensitive to cpt|| dbl deletion yes agar||| ||dcd1| mus81 ||sensitive to mms|| dbl deletion yes agar||| [[BR]] ||http://curation.pombase.org/pombe/curs/8a0da77ab1315722|| ||txl1 | txc1|| normal veg cell growth on glucose||both deleted, cga|| ||txl1 | txc1||normal level of protein-ubiquitin conjugates||deletion, gel elec|| ||txl1 | cut8||decreased cell pop growth on glucose||deletion, cga, agar, standrad temp|| ||txc1 | cut8||normal cell pop growth on glucose||deletion, cga, agar, standrad temp|| [[BR]] ||http://curation.pombase.org/pombe/curs/08562810fce65760|| ||rad3| tel1|| abolished histone H2A phosphorylation||both deleted, chip|| ||hta1| hta2|| normal protein localization to centromere||htaAQ hta1-S129A, hta2-S128A, chip, assayed_using rad21|| ||hta1| hta2|| normal protein localization to subtelomere||htaAQ hta1-S129A, hta2-S128A, chip, assayed_using rad21|| ||hta1| hta2|| normal chromosome segregation||htaAQ hta1-S129A, hta2-S128A, micro|| ||hta1| hta2|| normal legnth of telomere||htaAQ hta1-S129A, hta2-S128A, micro|| ||hta1| hta2|| decreased protein localization to rDNA||htaAQ hta1-S129A, hta2-S128A, chip assayed using(brc1)|| ||hta1| hta2|| decreased protein localization to telomere||htaAQ hta1-S129A, hta2-S128A, chip assayed using(brc1)|| ||hta1| hta2|| decreased protein localization to centromere otr||htaAQ hta1-S129A, hta2-S128A, chip assayed using(brc1)|| ||hta1| hta2|| loss of punctate nuclear localization||htaAQ hta1-S129A, hta2-S128A, micro assayed using(brc1)|| ||hta1| hta2|| normal cell pop growth on glucose||htaAQ hta1-S129A, hta2-S128A, cga, agar, stand temp, yes|| ||brc1| rqh1|| decreased cell pop growth on glucose||brc1-T672A rqh1-delta, cga, agar, stand temp, yes|| ||brc1| rqh1|| viable elongated veg cell||brc1-T672A rqh1-delta, micro|| ||brc1| rqh1|| viable elongated veg cell||brc1-delta rqh1-delta, micro|| ||hta1 | hta2 | rqh1|| viable elongated veg cell||htaAQ hta1-S129A, hta2-S128A, rqh1-delta, micro|| ||brc1| rqh1|| abnormal mitotic chromosome segregation||brc1-T672A rqh1-delta, micro|| ||brc1| rqh1|| abnormal mitotic chromosome segregation||brc1-delta rqh1-delta, micro|| ||hta1 | hta2 | rqh1|| abnormal mitotic chromosome segregation||htaAQ hta1-S129A, hta2-S128A, rqh1-delta, micro|| ||http://curation.pombase.org/pombe/curs/b6cb6d3911a0b608/|| ||pka1| sck1|| abolished cellular alpha alpha trehalase activity||both deleted, enzyme assay|| ||http://curation.pombase.org/pombe/curs/b63f265d4bdd37d2|| ||tsc1| leu1|| inviable cell pop on glucose||both deleted, cga, EMM|| ||tsc1| leu1|| normal cell pop growth glucose||both deleted, cga, low Nitrogen MM|| ||tsc1| leu1|| normal cell pop growth glucose||both deleted, cga, YES|| ||npr2| leu1|| inviable cell pop on glucose||both deleted, cga, EMM|| ||npr2| leu1|| normal cell pop growth glucose||both deleted, cga, low Nitrogen MM|| ||npr2| leu1|| normal cell pop growth glucose||both deleted, cga, YES|| ||npr2| cat1|| normal cell pop growth glucose||both deleted, cga, emm, agar|| ||tsc2| cat1|| normal cell pop growth glucose||both deleted, cga, emm, agar|| ||npr2| tor2|| normal cell pop growth glucose||deletion, tor2-287, cga, emm, agar|| ||tsc2| tor2|| normal cell pop growth glucose||deletion, tor2-287, cga, emm, agar||