Changes between Version 171 and Version 172 of ChromosomeSegregation


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Timestamp:
Mar 9, 2015, 10:18:26 PM (6 years ago)
Author:
vw253
Comment:

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  • ChromosomeSegregation

    v171 v172  
    3434
    3535||Pad1/Rpn11 and Mts3/Rpn12 are subunits of the lid subcomplex|| in PMID: 16149916 Mutations in the genes encoding these two subunits were isolated in a screen for mutants that were both esistant to methyl 2-benzimidazolecarbamate, a microtubule in- hibitor, and Ts for cell-cycle progression [19,20]. Ts mutations in both genes cause arrest of the cells in mitosis, probably because of a failure to degrade cyclin B/Cdc13 and securin/Cut2. ||-||
    36 
     36|| mde4 || Previous results showed that in interphase, when Mde4 is dephosphorylated, the Mde4-Pcs1 complex localizes to the nucleolus and to the kinetochores, which cluster at the nuclear periphery next to the spindle pole bodies (SPBs) [6,8]. As cells enter mitosis and Mde4 becomes phosphorylated, Mde4- Pcs1 leave the nucleolus but remain at the kinetochores [6,8]. [6. PubMed: 17627824]  [8. PubMed: 12689592]||
    3737 
    3838||phosphatase||||||||1703321,||