Changes between Version 188 and Version 189 of ChromosomeSegregation

Timestamp:

Apr 27, 2015, 9:41:45 PM (6 years ago)

Author:

vw253

Comment:

--

ChromosomeSegregation

@@ -36 +36 @@
 ||pck1||?????||targets ppe1?||
 ||pck1||?????||phosphorylates  mcm2,4,6, caf1, swi6,rad9, swi3, mrc1 crm1 and other importins||
-||Pad1/Rpn11 and Mts3/Rpn12 are subunits of the lid subcomplex|| ||?????|| in PMID: 16149916 Mutations in the genes encoding these two subunits were isolated in a screen for mutants that were both esistant to methyl 2-benzimidazolecarbamate, a microtubule in- hibitor, and Ts for cell-cycle progression [19,20]. Ts mutations in both genes cause arrest of the cells in mitosis, probably because of a failure to degrade cyclin B/Cdc13 and securin/Cut2. ||
+||Pad1/Rpn11 and Mts3/Rpn12 are subunits of the lid subcomplex||?????|| in PMID: 16149916 Mutations in the genes encoding these two subunits were isolated in a screen for mutants that were both esistant to methyl 2-benzimidazolecarbamate, a microtubule in- hibitor, and Ts for cell-cycle progression [19,20]. Ts mutations in both genes cause arrest of the cells in mitosis, probably because of a failure to degrade cyclin B/Cdc13 and securin/Cut2. ||
 || mde4 || ||?????| Previous results showed that in interphase, when Mde4 is dephosphorylated, the Mde4-Pcs1 complex localizes to the nucleolus and to the kinetochores, which cluster at the nuclear periphery next to the spindle pole bodies (SPBs) [6,8]. As cells enter mitosis and Mde4 becomes phosphorylated, Mde4- Pcs1 leave the nucleolus but remain at the kinetochores [6,8]. [6. PubMed: 17627824]  [8. PubMed: 12689592]||