Changes between Version 211 and Version 212 of ChromosomeSegregation


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Timestamp:
May 13, 2015, 8:49:02 AM (6 years ago)
Author:
vw253
Comment:

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  • ChromosomeSegregation

    v211 v212  
    4040||cdc20|| ?????|| When Cdc20 is overexpressed, securin can be degraded during interphase, whereas other destruction box proteins will remain stable. In cells lacking Cdc20, securin remains stable, and sister chromatids will not separate (Visintin et al., 1997).||
    4141||cut7|||?????|| In the temperature-sensitive cut7 mutant, spindle formation is blocked shortly after duplication of the SPB. The mitotic spindle radiating from the opposite poles cannot interdigitate and thus remains as a V shape (Hagan and Yanagida, 1992). The cut7- specific defect generates a condition whereby the bipolar attachment of the spindle to kinetochores is not achieved. Previously, we demonstrated that this defect causes an arrest in a mad2+-dependent manner (Kim et al., 1998). At the restrictive temperature the majority of Mad2-GFP was found on condensed chromosomes as one or more speckles (Fig. 4).||
    42 || fin1|| PMID: 23333317 PMID: 22684255 ||  priority papers for G2/M network||
     42|| fin1|| PMID:23333317 PMID:22684255 ||  priority papers for G2/M network||
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