Changes between Version 230 and Version 231 of ChromosomeSegregation


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Timestamp:
Oct 23, 2015, 8:39:48 PM (5 years ago)
Author:
vw253
Comment:

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  • ChromosomeSegregation

    v230 v231  
    1919
    2020||crb2||PMID:14739927 ||Finally, we show direct interaction between Rad3 and Crb2, which is inhibitory to Rad3 activity (direct enzyme regulator substrate) ||
    21 ||crb2||PMID:21098122 ||There are two pathways that lead to Crb2 localization at sites of DNA damage (10). One pathway requires two inde- pendent histone modifications: (i) phosphorylation of the C- terminal tail of histone H2A ||
     21
    2222||Tel1 ||PMID:21098122 ||Tel1 phosphorylation of histone H2A at DSBs depends on its interaction with the Nbs1 subunit of MRN complex (52). (add tel1 targets as histones)||
    23 || crb2 ||????||Find physical interaction with Rad9||
    2423||All histones||????||These are often not annotated with their roles in cell cycle regulation and repair, and so they are excluded from the graphs (also need to have specific nucleosome terms, 'what do you call a normal nucleosome?l' and 'centromere specific'||
    2524
    26 ||srw1||PMID:9571240, PMID:9736616 PMID:10921878 ||has no mitotic cell cycle regulation annotation||
     25
    2726|| fnx1 & 2||PMID: 18503766 || This wouldn't normally be a priority, but I'm putting it in becasue the exisitng transport GO annotations look a bit of a mess (stretch) ... need to get detailed phenotypes and then decide what it is possible to infer sensibly||
    2827||Scf complex||?????||-||