Changes between Version 290 and Version 291 of ChromosomeSegregation


Ignore:
Timestamp:
Mar 1, 2016, 9:57:24 PM (5 years ago)
Author:
vw253
Comment:

--

Legend:

Unmodified
Added
Removed
Modified
  • ChromosomeSegregation

    v290 v291  
    102102||ubc11 ubiquitin conjugating enzyme E2- ||annotation complete ||18/11/2015||
    103103||cut8 tethering factor for nuclear proteasome ||PMID:12653962 PMID:17178839|| -||
    104 ||pop1|| PMID:14970237||-||
    105 ||pop2|| PMID:14970237||-||
     104||pop1||PMID:14970237||-||
     105||pop2||PMID:14970237||-||
    106106===
    107107||dis1 ||PMID:16920624 plus…XMAP215/ TOG/Stu2-family homolog, binds microtubules and localizes to kinetochores (Nakaseko et al., 2001). Mutants in dis1 lack the chromosome alignment phase in metaphase and arrest with elongated spindles and segregated but unseparated chromosome pairs (Nabe- shima et al., 1998; Ohkura et al., 1988).dis1 mutants arrest with an activated spindle checkpoint and appear to ex- perience an increase in sister chromatid cosegregation (70%) at full restrictive temperature. Such cosegregation results when mono-oriented attachment of sister kineto- chores to microtubules from the same SPB is not corrected. Since dis1 mutants lack the phase of constant spindle length when chromosomes are properly aligned ||-||