Changes between Version 57 and Version 58 of ChromosomeSegregation

Timestamp:

Jan 7, 2015, 11:44:26 AM (6 years ago)

Author:

vw253

Comment:

--

ChromosomeSegregation

@@ -28 +28 @@
  *  mid1 is a plo1 substrate
  * from 21008122 In humans and both yeasts, DSBs are initially detected and processed by the Mre11-Rad50-Nbs1Xrs2 (MRN) nucleolytic protein complex in association with the Tel1ATM checkpoint kinase and the Ctp1CtIP/Sae2 DNA-end processing factor;...implies tel1 /rad50/nbs1 should be annotated to GO:0000729
-  * from 21098122 :The functions of ATM and ATR orthologs are intimately tied to the detection and nucleolytic processing of DSBs. ATMTel1 localizes at DSBs by interacting with Mre11-Rad50- Nbs1Xrs2 (MRN) protein complex, which directly binds DNA ends (12, 20, 24, 50, 52).  use these papers to annotate the missing connection between tel1 and the mre11 complex 
+ * HIGH PRIORITY from 21098122 :The functions of ATM and ATR orthologs are intimately tied to the detection and nucleolytic processing of DSBs. ATMTel1 localizes at DSBs by interacting with Mre11-Rad50- Nbs1Xrs2 (MRN) protein complex, which directly binds DNA ends (12, 20, 24, 50, 52).  use these papers to annotate the missing connection between tel1 and the mre11 complex 
 
  == anything which pins down the cell cycle annotations to the specific phase/transition they regulate ==