Changes between Version 59 and Version 60 of ChromosomeSegregation


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Timestamp:
Jan 7, 2015, 1:27:09 PM (6 years ago)
Author:
vw253
Comment:

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  • ChromosomeSegregation

    v59 v60  
    3030 * HIGH PRIORITY from 21098122 :The functions of ATM and ATR orthologs are intimately tied to the detection and nucleolytic processing of DSBs. ATMTel1 localizes at DSBs by interacting with Mre11-Rad50- Nbs1Xrs2 (MRN) protein complex, which directly binds DNA ends (12, 20, 24, 50, 52).  use these papers to annotate the missing connection between tel1 and the mre11 complex
    3131 * PMID: 14739927 Finally, we show direct interaction between Rad3 and Crb2, which is inhibitory to Rad3 activity (direct enzyme regulator substrate)
     32 * HIGH PRIORITY from 21098122 There are two pathways that lead to Crb2 localization at sites of DNA damage (10). One pathway requires two inde- pendent histone modifications: (i) phosphorylation of the C- terminal tail of histone H2A
    3233
    3334 == anything which pins down the cell cycle annotations to the specific phase/transition they regulate ==