Complementation

• (qualifiers: full, partial)
• If has a human ortholog is it associated with any disease?
• If has catalytic activity can you curate rate constant etc?
• If DNA binding do you know the binding specificity?
• Is the gene used in any experimental gene constructs?

syntax used for complementation

full complementation	qualifier=full
partial complementation	qualifier=partial
pombe gene X complements loss of homologous gene in other organism Y	functionally complements organismY geneX
loss of pombe gene is complemented by gene X from another organism Y	functionally complemented by organismY geneX
no complementation observed	does not functionally complement organismY + geneX
no complementation observed	is not functionally complemented by organismY + geneX
example string	/controlled_curation="term=complementation, functionally complements S. cerevisiae GSH2; qualifier=partial; db_xref=; date="