PMID | Pombe gene/allele | Organism complemented | gene complemented | phenotypes suppressed
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PMID:1327149 | tmp1 | S. cerevisiae | cdc8-1 | complements cell cycle defect | Val
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PMID:1922021 | tbp1 | S. cerevisiae | SPT15 | complements growth defect | Val
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PMID:2197558 | tbp1 | S. cerevisiae | SPT15 | complements growth defect | Val
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PMID:2227411 | suc1 | S. cerevisiae | cks1-null | complements ? | Val
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PMID:3063400 | leu1 | E. coli | leuB | Val
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PMID:3063400 | leu1 | S. cerevisiae | leu2 | Val
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PMID:9559549 | spt3 | S. cerevisiae | spt3-delta | partially complements | Val
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PMID:9693378 | mam4 | S. cerevisiae | Deltaste14 | complements | Val
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PMID:10050047 | hba1 | S. cerevisiae | Deltayrb2 | rescues cold sensitivity | Val
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PMID:1448066 | ade2 | E. coli | purA | E. coli carrying a mutation in purA can grow in MM-adenine when transformed with pombe ade2 | AL
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PMID:8663290 | rip1 | S. cerevisiae | RIP1 | RIP1 deletion mutant can grow on a non-fermentable carbon source (2% glycerol) when expressing pombe rip1
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PMID:8663290 | rip1 | S. cerevisiae | RIP1 | pombe rip1 restores 25-30% of ubiquinol-cytochrome c reductase activity in cerevisiae
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PMID:8663290 | rip1 | S. cerevisiae | RIP1 | pombe rip1 restores 65% of succinate-cytochrome c reductase activity in mitochondrial membrane in cerevisiae
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PMID:8663290 | rip1 | S. cerevisiae | RIP1 | pombe rip1 restores 70% of NADH-cytochrome c reductase activity in mitochondrial membrane in cerevisiae
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PMID:1409592 | ura3 | S. cerevisiae | URA1 | pombe ura3 makes cerevisiae ura1-delta ura+ when grown in an aerobic condition. Cells cease growth however under anaerobic conditions (WT cerevisiae can grow anaerobically unlike pombe) | AL
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PMID:10712694 | oxa101 | S. cerevisiae | OXA1 | Cerevisiae cells transformed with pombe oxa101 can grow on glycerol which oxa1 mutants in cerevisiae normally cannot, however, growth is slower than WT. | AL
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PMID:10712694 | oxa102 | S. cerevisiae | OXA1 | Cerevisiae cells transformed with pombe oxa102 can grow on glycerol which oxa1 mutants in cerevisiae normally cannot, however, growth is slower than wt but better than when complementing with oxa101. | AL
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PMID: | cyc1 | S. cerevisiae | CYC1 + CYC7 | cerevisiae double deletion for cyc1 and cyc7 cannot grow on glycerol (which is a non-fermentable carbon source in cerevisiae). S. cerevisiae transformed with Pombe cyc1 can grow on glycerol
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PMID:10234787 | stt3 | S. cerevisiae | STT3 | pombe stt3 suppress temperature sensitivity of cerevisiae sttr3-1 mutation when cells are grown on rich medium. It is not suppressed when grown on minimal medium. Glycosylation defect is also not supressed | AL
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PMID:8921872 | mag1 | E. coli | alkA/tag | pombe mag1 partially restores resistance of an alkA/tag E. coli double mutant to alkylation by MMS/MNNG/ENNG and PNNG | AL
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PMID:20106903 | vrs1 | S. cerevisiae | VAS1 | pombe vrs1 rescues the cytoplasmic form (growth assay) of VAS1 knockout | AL
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PMID:15075270 | liz1 | S. cerevisiae | FEN2 | pombe liz1 rescues growth of fen2 knockout on low pantothenate medium | AL
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PMID:15075270 | vht1 | S. cerevisiae | VHT1 | pombe vht1 rescues growth of VHT1 knockout on low biotin medium | AL
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PMID:17559414 | mpr1 | S. cerevisiae | Ypd1 | delta-ypd1 is lethal. Pombe mpr1 rescues growth. N-terminal truncationst of mpr1 also rescues growth | AL
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PMID:8765231 | gpm1 | S. cerevisiae | GPM1 | cerevisiae deleted for GPM1 cannot grow in YEPD medium. Pombe gpm1 rescues growth | AL
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PMID:8765231 | pma1 | S. cerevisiae | PMA1 | cerevisiae deleted for PMA1 grows small colonies and lacks membrane fraction ATPase activity | AL
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PMID:2112089 | ypt2 | S. cerevisiae | SEC4 | a ts cerevisiae sec4- mutant that cannot grow at high temp is rescued by pombe ypt2 | AL
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PMID:6294096 | adh1 | S. cerevisiae | ADR1-1, ADR2-delta | pombe adh1 complements a cerevisiae strain deficient in alcohol dehydrogenase activity | AL
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PMID:8879272 | rhp16 | S. cerevisiae | RAD16-delta | cerevisiae rad16delta are sensitive to UV and are deficient in nontranscribed dna repair. pombe rhp16 partially rescues survival upon UV radiation and nontranscribed dna repair | AL
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PMID:9001235 | dbr1 | S. cerevisiae | dbr1 | intron accumulation defect of a cerevisiae dbr1 mutant is complemented by pombe dbr1 | AL
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PMID:3912263 | tpi1 | S. cerevisiae | TPI1 | growth deficiency of s. cerevisiae N582-4B in glucose MM mitigated by pombe tpi1 | AL
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PMID:8299169 | his7 | E. coli | EcoCyc:EG10451 | pombe his7 rescues histidine auxotrophy in an E. coli hisI mutant | AL
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PMID:23640107 | oga1 | S. cerevisiae | STM1 | deletion of STM1 in cerevisiae makes them caffeine sensitive. pombe oga1 rescues this sensitivity | AL
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PMID:11095668 | pus1 | S. cerevisiae | PUS1 | deletion of PUS1 and LOS1 in cerevisiae makes them cunable to grow at 37 degrees. Pombe pus1 rescues this | AL
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PMID:3796591 | cdc2 | S. cerevisiae | CDC28 | pombe cdc2 fully complements growth defect of cerevisiae cdc28.4 but only when the introns are removed | AL
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PMID:7657644 | cam1 | S. cerevisiae | CMD1 | pombe cam1 supports growth of cerevisiae cmd1 | AL
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PMID:8675018 | anc1 | S. cerevisiae | ANC1 and ANC2 | pombe anc1 supports growth of cerevisiae ANC1 and ANC2 delta on non-fermentable carbon source | AL
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PMID:9737967 | myh1 | E. coli | MutY | pombe myh1 restores mutation rate in e. coli MutY mutant almost to WT level, probably within error of assay. They do have slightly different affinities for substrates though and kinetics | AL
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PMID:8021171 | tps1 | S. cerevisiae | TPS1 | pombe tps1 enables cerevisiae tps1-delta to grow on glucose (growth rate a bit lower than wt) and to have trehalose-6-p synthase activity (though lower than wt) also functional in stress response | AL
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PMID:11284010 | hut1 | S. cerevisiae | HUT1 | pombe hut1 alleviates cerevisiae ero1ts/hut1-delta DTT sensitivity | AL
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PMID:11754480 | SPBC428.11 | S. cerevisiae | MET17 | pombe SPBC428.11 restores O-acetylhomoserine and O-acetylserine sulphydrolase activity in a cerevisiae met17 mutant | AL
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PMID:2668944 | cyr1 | S. cerevisiae | CYR1 | pombe cyr1 resores low adenylate cyclase activity in cerevisiae but cannot be further activated by RAS2 | AL
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PMID:11124699 | gpi8 | S. cerevisiae | GPI8 | cerevisiae where expression of GPI8 is expressed is lethal, but can grow when pombe gpi8 is expressed | AL
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PMID:18388974 | sua1 | S. cerevisiae | MET3 | sua1 rescues methionine/cysteine auxotrophy of cerevisiae met3 mutant | AL
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PMID:7744766 | idi1 | S. cerevisiae | IDI1 | IDI1 cerevisiae deletion does not grow, idi1 rescues growth | AL
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PMID:7732725 | his1 | S. cerevisiae | HIS1 | A cerevisiae HIS1 mutant is a histidine auxotroph, his1 from pombe restores auxotrophy | AL
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PMID:8144551 | pka1 | S. cerevisiae | CDC25 | protein kinase A is necessary for cerevisiae cell growth, pombe pka1 rescues viability at restrictive temp in a CDC25 ts strain | AL
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PMID:8039497 | cdc7 | S. cerevisiae | CDC15 | pombe cdc7 restores colony formation, but somewhat poorly, in a cerevisiae CDC15 ts strain | AL
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PMID:7985419 | car1 | S. cerevisiae | CAR1 | pombe car1 restores growth on arginine as a nitrogen source in cerevisiae car1 mutant also restores arginase activity in the strain | AL
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PMID:10617635 | cpp1 | S. cerevisiae | RAM1 | pombe cpp1 restores growth at high temp in cerevisiae dpr1 mutant | AL
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PMID:12455993 | pct1 and pce1 | S. cerevisiae | CET1 and CEG1 | pombe pct1 AND pce1 support viability in a CET1 AND CEG1 straindeletion strain | AL
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PMID:12557275 | vht1 | S. cerevisiae | VHT1 | pombe vht1 supports growth in a VHT1 deletion strain on media with low biotin | AL
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PMID | Pombe gene/allele | Organism | gene | phenotypes suppressed
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PMID:1313771 | cdc25-22 | M. Musculus | Cdc25M2 | OEX restoring the temperature-conditional growth defect | Val
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PMID:1314161 | dis2-11 | A. thaliana | PP1-At | restores cs chromosome disjuction phenotype | Val
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PMID:1606618 | cdc25-? | D. melanogaster | string | rescues ts mutant | Val
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PMID:1606618 | cdc25-? | D. melanogaster | twine | rescues ts mutant | Val
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PMID:2120044 | cdc25-22 | D. melanogaster | string | rescues ts mutant | Val
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PMID:2120044 | cdc25-22 | D. melanogaster | Dm cdc2 | rescues ts mutant | Val
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PMID:2120045 | cdc2-? | D. melanogaster | Dm cdc2 | rescues ts mutant | Val
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PMID:7962194 | cdc2-33 | A. nidulans | nimXcdc2 | Val
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PMID:7476862 | cdc2delta | D. melanogaster | Dm cdc2 | capable of mating and producing four viable meiotic products, responds to nutritional starvation and to incomplete DNA synthesis, produces a 'wee' phenotype, and it is largely insensitive to the action of the S. pombe wee1+ mitotic inhibitor, hypersensitive to UV irradiation | Val
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PMID:1662986 | cdc25-? | H. sapiens | CDC25Hu2 | full rescue of ?? | Val
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PMID:2195549 | cdc25-? | H. sapiens | CDC25 | rescue of cell cycle defect | Val
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PMID:1937013 | cdc2-33 | A. thaliana | CDC2a | rescues cell cycle phenotype | Val
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PMID:1937013 | cdc2-33 | A. thaliana | CDC2b | rescues cell cycle phenotype | Val
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PMID:2000373 | cdc2-?? | Medicago sativa L. | cdc2Ms | rescues ts cell cycle phenotype | Val
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PMID:1983087 | ras1delta | H. sapiens | RAP1A | suppress defects in cell morphology and sporulation, not conjugation | Val
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PMID:1983087 | ras1delta | H. sapiens | RAP1B | suppress defects in cell morphology and sporulation, not conjugation | Val
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PMID:2663184 | rad13 | S. cerevisiae | RAD2 | repair defect | Val
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PMID:6347688 | cdc17 | S. cerevisiae | cdc9 | DNA ligase defect | Val
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PMID:7565716 | vps34-delta | D. discoideum | PIK1 | complemented the temperature-sensitive growth defect | Val
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PMID:7589895 | fbp1 | R. norvegecus | fbp2 | complemented fructose-1,6-bisphosphatase (Fru-1,6-Pase) activity | Val
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PMID:7808417 | wee1-50/mik1delta | D. melanogaster | Hel25E | mitotic catastrophe | Val
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PMID:7808417 | wee1-50/OEXcdc25 | D. melanogaster | Hel25E | mitotic catastrophe | Val
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PMID:8573790 | wee1-50/mik1 delta | D. melanogaster | Dwee1 | mitotic catastrophe | Val
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PMID:7816619 | pde1-mutant ? | A. thaliana | At PP2C | sterile phenotype, defective in cAMP phosphodiesterase | Val
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PMID:7816619 | pde1-mutant ? | A. thaliana | At Dr1 | sterile phenotype, defective in cAMP phosphodiesterase | Val
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PMID:7816619 | pde1-mutant ? | A. thaliana | TBP | sterile phenotype, defective in cAMP phosphodiesterase | Val
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PMID:7816619 | pde1-mutant ? | S. cerevisie | TBP | sterile phenotype, defective in cAMP phosphodiesterase | Val
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PMID:7885830 | dhp1-ts ? | M. musculus | Dhm1 | rescued the temperature-sensitivity | Val
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PMID:7885830 | dhp1delta | M. musculus | Dhm1 | rescued lethality | Val
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PMID:7962207 | cap1 | H. sapiens | CAP | elongation (CC) phenotype, propensity to sporulate | Val
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PMID:7962207 | cap1 | H. sapiens | CAP2 | elongation (CC) phenotype | Val
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PMID:8007985 | rad2 | H. sapiens | FEN1 | UV sensitivity | Val
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PMID:8041632 | cdc2-L7 | H. sapiens | scr2 | Val
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PMID:8041632 | cdc2-L7 | H. sapiens | scr3 | Val
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PMID:8041632 | cdc13-117 | H. sapiens | scr2 | Val
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PMID:8041632 | cdc13-117 | H. sapiens | scr3 | Val
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PMID:8045419 | wee1 several | X. laevis | ??? | Val
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PMID:8089179 | gtb1 | H. sapiens | TUBG1 | growth defect/ microtubule defects | Val
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PMID:8106391 | mutant25 ??? | C. kessleri | HUP1 | glucose uptake deficiency | Val
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PMID:8552193 | ??? | X. laevis | XORC2 | rescues mitotic catastrophe | Val
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PMID:8573795 | rad1-1 | H. sapiens | RACH2 | rescues checkpoint defect, restores UV resistance | Val
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PMID:8573795 | rad1-1/wee1-50 | H. sapiens | RACH2 | rescues lethality | Val
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PMID:8573795 | rad1-1/cdc25-22 | H. sapiens | RACH2 | partially restores the dose-dependent delay in mitotic entry after irradiation | Val
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PMID:9716408 | rad1 (mutant) | H. sapiens | RAD1 | complements UV sensitivity &checkpoint control defect | Val
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PMID:9828139 | rad1 (mutant) | H. sapiens | RAD1 | partially complements UV sensitivity & ionizing radiation sensitivity | Val
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PMID:8660701 | gsa1 | M. musculus | GSS | glutathione synthetase deficiency | Val
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PMID:8771785 | cdc3-124 | A. thaliana | PFN1 | Val
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PMID:8771785 | cdc3-124 | A. thaliana | PFN2 | Val
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PMID:8771785 | cdc3-124 | A. thaliana | PFN3 | Val
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PMID:8771785 | cdc3-124 | A. thaliana | PFN4 | Val
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PMID:8943031 | rad9-delta | H. sapiens | RAD9 | rescue degrees of sensitivity to hydroxyurea and gamma rays, & associated checkpoint control | Val
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PMID:9766521 | rad9-delta | M. musculus | Mrad9 | restores hydroxyurea resistance and early S phase checkpoint control, UV resistance minimally restored, and mutant cells remain sensitive to gamma radiation | Val
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PMID:10208430 | rad17 | H. sapiens | hRAD17 | partially revert its hydroxyurea and ionizing radiation hypersensitivity, but not its UV hypersensitivity | Val
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PMID:9013334 | ppe1-374 | H. sapiens | PP6 | restores morphology defects | Val
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PMID:9339378 | dis2-11 | M. musculus | Ppp1cc | restores cold sensitivity | Val
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PMID:9370289 | rae1-1 | H. sapiens | RAE1 | partially the temperature sensitivity (by increasing export at restrictive temperature) | Val
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PMID:9547260 | prp8-ts?? | H. sapiens | DBP2 | partially rescued the temperature-sensitive phenotype | Val
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PMID:9562621 | dis3-54 | S. cerevisie | Dis3 | complements | Val
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PMID:9729469 | gpi1 | H. sapiens | PIGQ | rescues lethality | Val
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PMID:10022880 | gap1 ??? | D. melanogaster | p120 Ras-GAP | complement the sterility | Val
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PMID:10409438 | dhm1delta | M. musculus | dhm1 | rescued lethality | Val
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PMID:7923372 | scd1-delta/scd1-1 | S. cerevisiae | CDC24 | partially restores conjugation. Weakly improves cell shape | AL
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PMID:21449051 | arc3-delta | H. sapiens | ARPC3 | ARPC3 restores colony formation of null mutant on solid medium, in liquid cells are very slow growing. Cells are rounder, wider and shorter than normal. Septum is sometimes mispositioned. | AL
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PMID:11115118 | krp1-delta | S. cerevisiae | KEX2 | Supports growth at low expression level (i.e. non-induced nmt1 promoter | AL
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PMID:11115118 | krp1-delta | S. cerevisiae | YPS1 | Supports growth when overexpressed, like the krp1-ts mutant (i.e. induced nmt1 promoter | AL
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PMID:10219997 | gsa1 - allele M379/8 | A. thaliana | GSH2 | cells can grow in presence of 2 mM cadmium. Cells produce similar quantities of GSH but slightly less phytochelatins | AL
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PMID:8914526 | gsa1 | A. thaliana | GSH2 | can't access paper on UCL subscription, see if I have it printed at work | AL
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PMID:9291132 | gsa1 - MN101 | A. thaliana | GSH2 | mutant transformed with GSH2 can grow as well as wt in presence of 0.5 mM cadmium but has lower GSH synthase activity than WT: GSH synthetase activity (nmol/h per mg of protein) in WT is 4.8 and in mutant transformed with GSH2 2.5 | AL
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PMID:7893167 | gpt2 | CHO (Chinese Hamster Ovary | L-G1PT | spores are viable when gpt2-delta is complemented by L-G1PT as opposed to null mutant | AL
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PMID:7499352 | tnr3 | S. cerevisiase | THI80 | pho4 is again repressible by thiamine and cells have high TPK activity | AL
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PMID:2020549 | can1 | S. cerevisiae | CAN1 | a can1-1 strain is sensitive to canavanine when grown in minimal media when expressing the CAN1 gene | AL
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PMID:9404894 | sla1 | S. cerevisiae | LHP1 | pombe cells carrying a sla1-deletion form abnormal tRNA intermediates during tRNA maturation (though the mature form appears normal). LHP1 restores the normal intermediate forms | AL
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PMID:9404894 | sla1 | H. sapiens | SSB | pombe cells carrying a sla1-deletion form abnormal tRNA intermediates during tRNA maturation (though the mature form appears normal). SSB restores the normal intermediate forms | AL
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PMID:18662319 | pgt1 | S. cerevisiae | HGT1 | pombe pgt1-delta cells that cannot grow on on GSH as sulphur source, can grow on GSH as sulphur source when expressing cerevisiae HGT1 | AL
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PMID:18662319 | pgt1 | S. cerevisiae | HGT1 | when overexpressing HGT1 cells become sensitive to high doses of GSH | AL
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PMID:11092853 | ppt1 | S. cerevisiae | COQ2 | cells expressing COQ2 have restored coenzyme Q10 production | AL
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PMID:11071923 | int6 | human | int6 | pombe int6-delta grow slower and less than wt in YE and MM. Human int6 rescues growth on plates (liquid not tested) | AL
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PMID:9368044 | crm1 | human | XPO1 | Human XPO1 rescues growth defect at cold temp in the crm1-809 mutant | AL
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PMID:2112088 | ryh1 | human | Rab6 | pombe ryh1-delta doesn't grow at 36 degrees, human rab6 rescues growth defect | AL
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PMID:3553962 | cdc2 | human | CDK1 | pombe cdc2-delta is elongated and growth-arrested. This is rescued by CDC2 | AL
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PMID:1944283 | cdc2 | human | CDK1 | human CDK1 fully rescues pombe cdc2-33 | AL
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PMID:1435723 | byr2 | S. cerevisiae | STE11 | cerevisiae STE11 enables a ste8 mutant to mate and sporulate on sporulation medium. Mat-pm is expressed. | AL
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PMID:10373512 | dss1 | H. sapiens | SHFM1 | human SHFM1 complements growth arrest of pombe dss1 knockout | AL
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PMID:23447405 | ras1 | H. sapiens | HRAS | morphology and pheromone response, tea1 localization and mating partially restored when expressed under control of endogenous promoter | AL
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PMID:23447405 | ras1 | H. sapiens | KRAS | morphology and pheromone response, tea1 localization and mating partially restored when expressed under control of endogenous promoter | AL
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PMID:23447405 | ras1 | H. sapiens | NRAS | mating and tea1 localization partially restored but will only restore morphology and pheromone response partially when overexpressed | AL
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PMID:12402243 | gtb1 | S. japonicus | gtb1 | viability of pombe gtb1-delta mutant (plasmid loss experiment) maintained when japonicus gtb1 is expressed, cells grows as fast as WT | AL
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PMID:11729194 | pnk1 | Human | PNKP | delta-pnk1 cells have no 3'-DNA phosphatase activity. These cells expressing PNKP have 3'-DNA phosphatase activity | AL
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PMID:11729194 | pnk1 | Human | PNKP | delta-pnk1 cells are sensitive to gamma irradiation and camptothecin, PNKP restores normal resistance | AL
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PMID:22748672 | pnk1 | cerevisiae | TPP1 | delta-pnk1 cells are sensitive to gamma irradiation, camptothecin, EMS, MMS, and H2O2. TPP1 restores normal resistance | AL
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PMID:22692683 | ura3 | human | DHODH | ura3-delta uracil auxotrophy rescued by DHODH | AL
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PMID:7657644 | cam1 | 'vertebrate' | vCaM | pombe cam1-delta mutant can grow when it is swapped for vertebrate calmodulin | AL
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PMID:21091378 | txl1 | h. sapiens | TXNL1 | pombe cut8-delta and txl1-delta mutant can grow when expressing TXNL1 | AL
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PMID:11030744 | dpm1 | t. reesei | dpm1 | pombe dpm1 deletion mutants do not sporulate, but can when expressing t. reesei dpm1 | AL
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PMID:11030744 | cdc2 | G. gallus | cdc2 | show how pombe cdc2 deletion mutant and cdc2-33 is complemented by gallus gallus cdc2. Also shows effects of mutations in chicken cdc2 on pombe | AL
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PMID:8021171 | tps1 | S. cerevisiae | TPS1 | cerevisiae tps1 enables pombe tps1-delta to make trehalose | AL
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PMID:11284010 | hut1 | S. cerevisiae | HUT1 | cerevisiae hut1 enables pombe hut1-delta to grow on DTT at 37 degrees | AL
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PMID:6765174 | fur4 | S. cerevisiae | FUR4 | cerevisiae fur4 enables pombe fur4 and ura4 mutant to grow on uracil | AL
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PMID:10996309 | rad9 | H. sapiens | BCL2 | BCL2 partially restores resistance to MMS IR and UV in pombe rad9-delta mutants | AL
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PMID:10850973 | tol1 | S. cerevisiae | MET22 | tol1 deletion does not grow, hal2 rescues growth | AL
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PMID:7732727 | plc1 | S. cerevisiae | PLC1 | plc1 deletion does not grow on MM or at high temp on YPD, PLC1 rescues growth | AL
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PMID:7987414 | spi1 | N. tabacum | RAN-A1 | dosage rescue of a pim1-46 mutant, same as spi1 does | AL
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PMID:24298023 | lot5 | H. sapiens | CLNS1A | growth defect rescued | AL
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PMID:9455919 | gtp2 | hamster | Dpagt1 | growth and tunicamycin resistance rescued | AL
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PMID:1286615 | cdc25 | D. melanogaster | twine | growth of ts mutant rescued | AL
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PMID:9374539 | rpn11 | human | PSMD14 | growth on emm plates restored in deletion mutant | AL
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PMID:9136929 | mcs4 | S. cerevisiae | SSK1 | SSK1 rescues inviability of mcs4-13 cdc25-22 cells | AL
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PMID:8078473 | ste13 | D. melanogaster | ME31B | rescues sterility of ste13-delta | AL
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PMID:9092625 | rad31 | S. cerevisiae | AOS1 | AOS1 rescues slow growth and radiation sensitivity of deltarad31 | AL
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PMID:19120452 | coq10 | human | COQ10A | human coq10A rescues growth deficiency of deletion mutant on minimal medium | AL
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