Changes between Version 588 and Version 589 of CuratorMeeting


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Timestamp:
Jan 13, 2015, 10:03:33 AM (6 years ago)
Author:
vw253
Comment:

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  • CuratorMeeting

    v588 v589  
    4848 
    4949 * annotate to protein complex ID (can get from PRO)?
    50  
    51  * example: PMID:18723846 has direct assays showing ORC binding to origin DNA, but doesn't distinguish subunits; from other work, it's known that some but not all ORC subunits actually make contact with DNA. Annotate all to DNA binding anyway, with or without contributes_to, or annotate to a complex ID? (I'd prefer the latter but will it break anything?)
    52   * same paper: similar issue for annotation extension - cdt1 or cdc18 increase ORC origin binding - put complex ID in has_regulation_target ext?
     50   * example: PMID:18723846 has direct assays showing ORC binding to origin DNA, but doesn't distinguish subunits; from other work, it's known that some but not all ORC subunits actually make contact with DNA. Annotate all to DNA binding anyway, with or without contributes_to, or annotate to a complex ID? (I'd prefer the latter but will it break anything?)
     51   * same paper: similar issue for annotation extension - cdt1 or cdc18 increase ORC origin binding - put complex ID in has_regulation_target ext?
    5352
    5453 * protein domain specific binding, see example in e-mail
    55 
    5654
    5755 * discuss Rama's question about "response to" extensions