Changes between Version 13 and Version 14 of GOAnnotationGuidelines


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Timestamp:
Jan 27, 2015, 5:05:07 PM (6 years ago)
Author:
vw253
Comment:

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  • GOAnnotationGuidelines

    v13 v14  
    209209  * Can you make any further annotations based on what SGD has? (Note reasons why annotations cannot be transferred; 1:1 is easiest)
    210210
     211
     212=== Making GO process annotations from IMP ===
     213
     214We use GO annotations to describe direct involvement in a process, or its regulation (see below for more detail on regulation). We don't  annotate indirect upstream effects. Caution must therefore be used when using IMP to make process annotation, as it often isn't clear whether the effect is directly involved, regulation, or only affecting a process indirectly.
     215 
     216Often a number of phenotypes are used to make a GO annotation. [[BR]]
     217 
     218Example 1
     219 dil1 in /curs/c7fac5251ee4f493/ro/ where annotation to dynein-driven meiotic oscillatory nuclear movement with IMP is based on a combination of phenotypes :
     220 * decreased meiotic recombination
     221 * horsetail movement abolished
     222 * unequal meiotic chromosome segregation
     223 * decreased protein localization to microtubule cytoskeleton
     224
     225Example 2
     226 nda3 and mug164 annotations to intracellular distribution of mitochondria with IMP is based on
     227 * abolished mitochondrion inheritance
     228 * mitochondrial aggregation at cell tip
     229 * normal mitochondrial fission
     230 * normal mitochondrial fusion
     231
     232
     233=== Regulation in GO , describe here ===
     234
    211235----
    212236[WikiStart Return to main page] or [CurationGuidelines Curation Guidelines]