Changes between Version 84 and Version 85 of GOAnnotationGuidelines


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Timestamp:
Feb 25, 2015, 6:41:43 PM (6 years ago)
Author:
vw253
Comment:

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  • GOAnnotationGuidelines

    v84 v85  
    6161
    6262   *  When to make a GO process  annotation 
    63       *   GO or phenotype  (update)
    64 
    65  === Making GO process annotations from IMP ===
    66 
    67 We use GO annotations to describe direct involvement in a process, or its regulation (see below for more detail on regulation). We don't  annotate indirect upstream effects. Caution must therefore be used when using IMP to make process annotation, as it often isn't clear whether the effect is directly involved, regulation, or only affecting a process indirectly.
     63      *   GO or phenotype  ?
     64         * We use GO annotations to describe direct involvement in a process, or its regulation (see below for more detail on regulation). We don't  annotate indirect upstream effects. Caution must therefore be used when using IMP to make process annotation, as it often isn't clear whether the effect is directly involved, regulation, or only affecting a process indirectly.
    6865 
    6966Often a number of phenotypes are used to make a GO annotation. [[BR]]
    7067 
    71 Example 1
    72  dil1 in /curs/c7fac5251ee4f493/ro/ where annotation to dynein-driven meiotic oscillatory nuclear movement with IMP is based on a combination of phenotypes :
    73  * decreased meiotic recombination
    74  * horsetail movement abolished
    75  * unequal meiotic chromosome segregation
    76  * decreased protein localization to microtubule cytoskeleton
     68        * Example 1 dil1 in /curs/c7fac5251ee4f493/ro/ where annotation to dynein-driven meiotic oscillatory nuclear movement with IMP is based on a combination of phenotypes :
     69            * decreased meiotic recombination
     70            * horsetail movement abolished
     71            * unequal meiotic chromosome segregation
     72            * decreased protein localization to microtubule cytoskeleton
    7773
    78 Example 2
    79  nda3 and mug164 annotations to intracellular distribution of mitochondria with IMP is based on
    80  * abolished mitochondrion inheritance
    81  * mitochondrial aggregation at cell tip
    82  * normal mitochondrial fission
    83  * normal mitochondrial fusion
     74         * Example 2 nda3 and mug164 annotations to intracellular distribution of mitochondria with IMP is based on
     75            * abolished mitochondrion inheritance
     76            * mitochondrial aggregation at cell tip
     77            * normal mitochondrial fission
     78            * normal mitochondrial fusion
    8479
    85  
    8680   * Regulation
    8781       *  [http://www.geneontology.org/GO.annotation.conventions.shtml#regulationTerms  GOC Regulation]