Changes between Version 116 and Version 117 of MidoriCuratedPapers


Ignore:
Timestamp:
Jun 10, 2015, 5:26:02 PM (5 years ago)
Author:
mah79
Comment:

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  • MidoriCuratedPapers

    v116 v117  
    4545||cdc21-M68(unknown) mcm4 C-terminus overexpression [note: says overexp piece from BamHI site to end, but the only BamHI site I saw looks too close to N-term to yield fragment in fig 1 gel||fypo:2061||
    4646
    47 
    48 [[BR]]
    49 ||PMID:19197239||new session||
    50 ||top1delta tdp1delta||FYPO: sensitive to camptothecin ev. cell growth||
    51 
    52 [[BR]]
    53 ||PMID:8838655||new session||
    54 ||mcm2||GO:0005634||extension: throughout cell cycle||
    55 ||mcm5||GO:0005634||extension: throughout cell cycle||
    56 
    57 [[BR]]
    58 ||PMID:12136010||new session||
    59 ||tsc1 leu1||fypo:46; ev cell growth assay; cond. limiting leu||
    60 ||tsc1 ade2||fypo:46; ev cell growth assay; cond. limiting ade||
    61 ||tsc2 leu1||fypo:46; ev cell growth assay; cond. limiting leu||
    62 ||tsc2 ade2||fypo:46; ev cell growth assay; cond. limiting ade||
    63 ||tsc1 tsc2||fypo:46; ev cell growth assay; cond. limiting ade||
    6447
    6548[[BR]]
     
    132115
    133116||PMID:9658174||
    134 ||gene expression - Mcm2, Mcm4, Mcm5, Mcm6||protein levels constant throughout cell cycle (ev: western)||
    135117||annotated physical interactions||no change throughout cell cycle||
    136118||negative result||no physical interaction between Mcms and Cdc18||
     
    138120[[BR]]
    139121||PMID:9705504||
    140 ||gene expression - Mcm3||protein level constant throughout cell cycle (ev: western)||
    141 ||GO mcm3 nucleus 5634 IDA||extension: throughout cell cycle||
    142122||mcm3-mcm5 phys int "tight"||what to do about interaction strength/affinity?||
    143123
     
    150130
    151131[[BR]]
    152 ||PMID:10388806||
    153 ||many, many double and triple mutant phenotypes||
    154 ||rum1+ overexp, cdc18-K46||fypo:1427 facs||
    155 ||rum1+ overexp, cdc23-M36||fypo:1427 facs||
    156 ||rum1+ overexp, cdc6(pold-1)||fypo:1427 facs||
    157 ||rum1+ overexp, orc1(orp1-4)||fypo:1427 facs||
    158 ||rum1+ overexp, cdc17-K42||fypo:1426 facs||
    159 ||rum1+ overexp, cdc24-g1||fypo:1426 facs||
    160 ||rum1+ overexp, cdc20-M10||fypo:1426 facs||
    161 ||rum1+ overexp, rad4-116||fypo:1426 facs||
    162 ||rum1+ overexp, cdc1-7||fypo:1428 facs||
    163 ||rum1+ overexp, cdc10-V50||fypo:1428 facs||
    164 ||rum1+ overexp, pol1-1||fypo:1428 facs||
    165 ||rum1+ overexp, mcm2(cdc19-P1)||fypo:1428 facs||
    166 ||rum1+ overexp, mcm4(cdc21-M68)||fypo:1428 facs||
    167 ||rum1+ overexp, cig1delta::ura4+||fypo:1425 facs, enlarged nuc fypo:344 ev: micr, elong fypo:839 ev: micr||
    168 ||rum1+ overexp, cig2delta::ura4+||fypo:1425 facs, enlarged nuc fypo:344 ev: micr, elong fypo:839 ev: micr||
    169 ||rum1+ overexp, cig1delta::ura4+, cig2delta::ura4+||fypo:1428 facs||
    170 ||cdc13delta::ura4+, cdc10-V50||fypo:1428 facs; elong fypo:839 ev: micr, cond high temp||
    171 ||cdc13delta::ura4+, mcm2(cdc19-P1)||fypo:1428 facs; elong fypo:839 ev: micr, cond high temp||
    172 ||cdc13delta::ura4+, mcm4(cdc21-M68)||fypo:1428 facs; elong fypo:839 ev: micr, cond high temp||
    173 ||cdc13delta::ura4+, cdc6(pold-1)||fypo:1428 facs; elong fypo:839 ev: micr, cond high temp||
    174 ||cdc13delta::ura4+, cdc18-K46||fypo:1428 facs; elong fypo:839 ev: micr, cond high temp||
    175 ||cdc13delta::ura4+, cdc18delta::p[nmt*.cdc18+-LEU2]||fypo:1428 ev facs, fypo:1430 ev:facs||
    176 ||cdc13delta::ura4+, mcm2delta::his3+||fypo:1428 ev facs, abn chr morph fypo:848 ev: 'other' (for PFGE)||
    177 ||cdc13delta::ura4+, mcm4delta::his3+||fypo:1428 ev facs, abn chr morph fypo:848 ev: 'other' (for PFGE)||
    178 
    179 [[BR]]
    180 ||PMID:19286980||
    181 ||psd1delta,psd2delta||viable rich med, std temp; viable minimal med, std temp||
    182 ||psd1delta,psd3delta||viable rich med, std temp; viable minimal med, std temp||
    183 ||psd2delta,psd3delta||viable rich med, std temp; viable minimal med, std temp||
    184 ||psd1delta,psd2delta||normal cell morph rich med, std temp, limited eth pco:169|
    185 ||psd1delta,psd3delta||normal cell morph rich med, std temp, limited eth pco:169||
    186 ||psd2delta,psd3delta||normal cell morph rich med, std temp, limited eth pco:169||
    187 ||psd1delta,psd2delta,psd3delta||viable rich med, std temp; inviable minimal med, std temp||
    188 ||psd1delta,psd2delta,psd3delta||fypo:38, minimal med, std temp; rich med, std temp||
    189 ||psd1delta,psd2delta,psd3delta||decr PE fypo:1285 rich med, minimal, minimal + ethanolamine; all std temp||
    190 ||psd1delta,psd2delta,psd3delta||incr PS fypo:1505 rich med, minimal, minimal + ethanolamine; all std temp||
    191 ||psd1delta,psd2delta,psd3delta||normal PC fypo:1506 rich med, minimal, minimal + ethanolamine; all std temp||
    192 ||psd1delta,psd2delta,psd3delta||normal PI fypo:1507 rich med, minimal, minimal + ethanolamine; all std temp||
    193 ||psd1delta,psd2delta,psd3delta||fypo:1496 minimal pco:169 std temp||
    194 ||psd1delta,psd2delta,psd3delta||fypo:339 minimal pco:169 std temp||
    195 ||psd1delta,psd2delta,psd3delta||fypo:20 minimal pco:169 std temp||
    196 ||psd1delta,psd2delta,psd3delta||fypo:21 minimal pco:169 std temp||
    197 ||psd1delta,psd2delta,psd3delta||fypo:1390 minimal pco:169 std temp||
    198 ||psd1delta,psd2delta,psd3delta||fypo:672 rich pco:154 std temp||
    199 ||psd1delta,psd2delta,psd3delta||fypo:673 rich pco:154 std temp||
    200 ||psd1delta,psd2delta,psd3delta||fypo:5 ext has_penetrance(FYPO_EXT:0000003) minimal pco:154 std temp||
    201 ||psd1delta,psd2delta,psd3delta||fypo:5 ext has_penetrance(FYPO_EXT:0000001) minimal pco:169 std temp||
    202 ||psd1delta,psd2delta,psd3delta||fypo:161 rich pco:169 std temp||
    203 ||psd1delta,psd2delta,psd3delta||fypo:182 rich pco:169 std temp||
    204 ||all evidence cell growth or microscopy as appropriate||
    205 
    206 [[BR]]
    207132
    208133||PMID:19168988||
    209 ||note: SPAPB2B4.04c has pmc1 as synonym (used in the paper), so document allele synonyms||
    210 ||SPAPB2B4.04cdelta,cta5delta||fypo:1419 rich med std temp||
    211 ||SPAPB2B4.04cdelta,SPCC1672.11cdelta||fypo:1487 fypo:636 rich med std temp||
    212 ||pmr1delta,cta5delta||fypo:1487 fypo:636 rich med std temp||
    213 ||pmr1delta,SPCC1672.11cdelta||fypo:1487 fypo:636 rich med std temp||
    214 ||cta5delta,SPCC1672.11cdelta||fypo:1487 fypo:636 rich med std temp||
    215 ||SPAPB2B4.04cdelta,cta5delta||fypo:98 ext has_expressivity(FYPO_EXT:0000001) rich std temp||
    216 ||SPAPB2B4.04cdelta,cta5delta||fypo:92 ext has_expressivity(FYPO_EXT:0000001) rich std temp||
    217 ||SPAPB2B4.04cdelta,SPCC1672.11cdelta||fypo:98 ext has_expressivity(FYPO_EXT:0000001) rich std temp||
    218 ||SPAPB2B4.04cdelta,cta5delta||fypo:286 minimal std temp||
    219 ||SPAPB2B4.04cdelta,SPCC1672.11cdelta||fypo:286 minimal std temp||
    220 ||SPAPB2B4.04cdelta,cta5delta, overexp pmr1+||fypo:1020 minimal std temp||
    221 ||SPAPB2B4.04cdelta,cta5delta||fypo:1020 pco:114 minimal std temp||
     134||note: SPAPB2B4.04c has pmc1 as synonym (used in the paper); documented allele synonyms||
    222135||multi-way genetic interaction||overexp pmr1+ sup (SPAPB2B4.04cdelta,cta5delta fypo:98)||
    223136||gene expression||pmr1+ > SPAPB2B4.04c+ > cta5+ during veg growth GO:0072690, but nothing else shown (e.g. change upon stimulus/during GO BP); one measurement||
     
    228141||hsk1 gene exp||both mRNA and protein "relatively constant throughout cell cycle"||
    229142||dfp1 C-term del, exact residues not specified||inviable; no further data||
    230 ||dfp1 him1-3A, chk1delta::ura4+||cut annotation_extension=has_penetrance(FYPO_EXT:0000002), micr, HU added||
    231 ||cds1delta::ura4+,chk1delta::ura4+||cut annotation_extension=has_penetrance(FYPO_EXT:0000001), micr, HU added||
    232143||Dfp1 "hyperphosphorylated" in presence of HU||
    233144
     
    240151
    241152||PMID:10490657||
    242 ||orc1 GO:790||throughout cell cycle||
    243 ||mcm6 go:5634||throughout cell cycle||
    244153||lots of Mcm2 & Mcm6 in unspecified "soluble" fraction||throughout cell cycle||
    245 ||cdc10-129, overexp cdc18+||normal prot loc to chromatin fypo:1509; annotation_extension=assayed_using(PomBase:SPBC211.04c)||
    246 ||cdc10-129, knockdown cdc18+||abol prot loc to chromatin fypo:1508; annotation_extension=assayed_using(PomBase:SPBC211.04c)||
    247154
    248155[[BR]]
    249156
    250157||PMID:10588642||
    251 ||mcm6 nucleus go:5634||throughout cell cycle||
    252 ||mcm2/cdc19-P1, crm1-11R||fypo:838 prot loc; high temp; annotation_extension=assayed_using(PomBase:SPBC211.04c)||
    253 ||mcm4/cdc21-M68, crm1-11R||fypo:838 prot loc; high temp; annotation_extension=assayed_using(PomBase:SPBC211.04c)||
    254 ||mcm2/cdc19-P1, mcm3-HA||fypo:783 prot loc; high temp; annotation_extension=assayed_using(PomBase:SPBC4.04c)|assayed_using(PomBase:SPCC16A11.17)|assayed_using(PomBase:SPBC211.04c)||
    255 ||mcm2/cdc19-P1, mcm3-HA||fypo:1424 prot loc; high temp; annotation_extension=assayed_using(PomBase:SPBC4.04c)|assayed_using(PomBase:SPCC16A11.17)||
    256 ||mcm4/cdc21-M68, mcm3-HA||fypo:783, fypo:1424 all prot loc; high temp; annotation_extension=assayed_using(PomBase:SPBC4.04c)|assayed_using(PomBase:SPCC16A11.17)|assayed_using(PomBase:SPBC211.04c)||
    257 ||crm1-809, mcm3-HA||fypo:838 prot loc; low temp; annotation_extension=assayed_using(PomBase:SPBC4.04c)|assayed_using(PomBase:SPCC16A11.17)|assayed_using(PomBase:SPBC211.04c)||
    258158||GFP-beta-galactosidase + SV40 NLS||nucleus||
    259159||GFP-beta-galactosidase + mcm2-M9 residues 5-10 (mutated NLS1)||cytoplasm||
    260160||GFP-beta-galactosidase + Mcm2 residues 114-118 (NLS2)||cytoplasm||
    261 ||mcm2/cdc19, mcm2-M9 overexp||inviable||
    262 ||mcm2/cdc19, mcm2-M9 overexp, mcm3-HA||inviable; fypo:783, fypo:1424 all prot loc; std temp; annotation_extension=assayed_using(PomBase:SPCC1682.02c)|assayed_using(PomBase:SPCC16A11.17)|assayed_using(PomBase:SPBC211.04c)||
    263 ||crm1-809, mcm2+ overexp||fypo:783; prot loc; low temp; annotation_extension=assayed_using(PomBase:SPBC4.04c)||
    264 ||crm1-809, mcm2-M2||fypo:783; prot loc; low temp; annotation_extension=assayed_using(PomBase:SPBC4.04c)||
    265 ||crm1-809, mcm2-M9||fypo:783; prot loc; low temp; annotation_extension=assayed_using(PomBase:SPBC4.04c)||
    266 ||crm1-809, mcm2-M10||fypo:783; prot loc; low temp; annotation_extension=assayed_using(PomBase:SPBC4.04c)||
    267 ||crm1-809, mcm2-D6||fypo:783; prot loc; low temp; annotation_extension=assayed_using(PomBase:SPBC4.04c)||
    268 ||crm1-809, mcm2-D7||fypo:783; prot loc; low temp; annotation_extension=assayed_using(PomBase:SPBC4.04c)||
    269 
    270 [[BR]]
    271 ||PMID:10747035||
    272 ||mcm4 nucleus go:5634||throughout cell cycle||
    273 ||cdc18+ overexp; mcm4 cdc21-M68||no rereplication; normal neg reg initiation?||
    274161
    275162[[BR]]