Changes between Version 1 and Version 2 of Modification


Ignore:
Timestamp:
Jan 27, 2015, 1:29:55 PM (6 years ago)
Author:
vw253
Comment:

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  • Modification

    v1 v2  
    11== Modification (and other "substrate is" annotations) ==
    22 
    3  * Make the modification annotation explicitly on the molecule which is being modified (and if known, add the modified residues).
     3 Modification annotations are annotated on the gene product which is being modified  (i.e the modified target)
     4
     5 Annotation extensions can be used to capture additional supporting data including
     6
     7   * The molecule doing the modifying (i.e the protein kinase for a phosphorylation, the phosphatase for dephosphorylation)
     8      * In this case you should ensure that you have annotated the  modifier with the molecular fiunction and substrate
     9 
     10
     11(and if known, add the modified residues).
    412  * If you are adding the residues, and the residues numbers apply to a  mature form of the protein, not the precursor translation, make sure that you request a pro ID for the shorter form, and put this in an annotation_extension has_direct_input(PR:xxxxx) so that the residues you specify matches the molecule in this extension.
    513  * See [wiki:AnnotationExtensionSyntax AnnEx Syntax] and [wiki:DescribingResidues describing residues modified or mutated] for "residue=" syntax