Version 16 (modified by 7 years ago) (diff) | ,
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Examples of distant orthologs not picked up by most ortholog predictors
- Sfr1 / MEI5 http://pfam.sanger.ac.uk/family/PF10376 (conserved to human)
- Rum1 / SIC1
- ipk1 / IPK1 (orthoMcl only)
- orc6 / ORC6 pfam.sanger.ac.uk/family/PF05460
- APC13 / YDR260C http://pfam.sanger.ac.uk/protein/O74358
- SPCC622.10c -> A. gossypii AGL158C (fasta) which is is syntentic ortholog of S. cerevisiae YDR166C
- rrn10/ RRN10 (small) (fungal only) http://pfam.sanger.ac.uk/family/PF05234
- SPCC553.01c/ YGR042W (to human) http://pfam.sanger.ac.uk/family/PF10382
- Sds3 /YIL084C (KOGS only) http://pfam.sanger.ac.uk/family/PF08598
- Swi5/SAE3 http://pfam.sanger.ac.uk/family/PF07061
- Sus1/SUS1 (OrthoMcl? only) http://pfam.sanger.ac.uk/family/PF10163
- Mediator complex subunits (add details)
- APC complex subunits (add details)
- Atp15/ATP15 (KOGS only) http://pfam.sanger.ac.uk/family/PF04627
- SPCC297.06c / YKL142W http://pfam.sanger.ac.uk/family/PF07957
- vps51 OrthoMCL builds to human but not cerevisiae, others miss most
- scm3 human HJURP PMID:19563746 http://pfam.xfam.org/family/PF10384
- mzt1 human MZT1 http://pfam.xfam.org/family/PF12554
- vph2 sequence orphan-> fungal specific-> vertebrate http://pfam.xfam.org/family/PF11712
- cwf20 http://pfam.xfam.org/family/PF10253
- sfc3 http://pfam.xfam.org/family/PF04182
- nrm1 http://pfam.xfam.org/family/PF08528
- SPAC3A12.19 mrpl27 http://pfam.xfam.org/family/PF09809
- Vta1 family http://pfam.xfam.org/family/PF04652
- hop1 YIL072W PMID:15226405;
- SPAC3A12.08
- Spd1 YLR437C http://pfam.xfam.org/family/PF0859
- apm3 YBR288C PMID:14745133
- sst6 YCL008C PMID:14745133
- ker1 PMID:15647272
- cdt1 PMID:11836525
- nse1 PMID:12966087
- cox18 (pers. comm. Nathalie.Bonnefoy) not reciprocal best hits but SPCC1442.15c is the functional ortholog of S. cerevisiae COX18
- SPBC776.06c YOR129C http://pfam.xfam.org/family/PF07792
- SPAC23H4.08 YDL115C http://pfam.xfam.org/family/PF08574
- rap1 http://pfam.xfam.org/family/PF09197
- Hos3 HSK1 (directed search) http://pfam.xfam.org/family/PF08227
- slx4 YLR135W http://pfam.xfam.org/family/PF09494
- SPAC4D7.10c YOL148C (hAT subunit)
- SPACUNK4.15 YGR247W
- SPCC126.13c SAP18 family
- SPAC1F3.07c YLR033W
- SPACC11E10.04 YMR282C
- SPAC7D4.11c YLR440C
- SPBC2A9.04cYDR143c
- SPBC336.08 = spc24
- SPCC188.04c = spc25 Hiroshi PUB, I had an error
- rec10
- sgo1
- sgo2
- SPAC19D5.09c (ctf8)- the ortholog of YHR191C (CTF8),
- SPBC106.05c was identified in a targeted search for the ortholog of YDR322C-A
- SPAC1002.02|YLR018C (pers. comm. Maria Novatchkova) from Psi-blast, family included in Pfam PF08058
- SPC32A11.01|YOR188W (pers. comm. Maria Novatchkova) from Psi-blast, family submitted to Pfam
- SPCC417.02 | YKL138C-A (S. pombe Hos3 identified as ortholog of
- kinetochores DASH complex component HSK3, targeted search for ortholog of new S. cerevisiae gene YKL138C-A), family submitted to Pfam
- shf1
- swi5/sus1
- qci9
- sds3
other egs
- 1. Book chapter
- 2. ortholog table diffs