wiki:OrthologInventoriesNoPom

Version 19 (modified by val_wood, 8 years ago) (diff)

--

Known pombe gene losses

misc

  • YAT1 YAR035W carnitine O-acetyltransferase
  • CYS4 YGR155W cystathionine beta-synthase
  • TAZ1 YPR140W TAfaZzin
  • YJL055W involved in the metabolism of purine and pyrimidine base analogues
  • HMO1 YDR174W rDNA-binding component of the Pol I transcription system
  • YPC1 YBR183W
  • HHO1 YPL127C histone H1
  • STE18 YJR086W gamma subunit of G protein
  • PDE2 YOR360C high affinity 3',5'-cAMP phosphodiesterase
  • KXD1 YGl079W
  • VID22
  • YGR071C

Glycogen metabolism

  • GLC3 YEL011W glycogen branching enzyme
  • GDB1YPR184W glycogen debranching enzyme
  • GPH1, YPR160W glycogen debranching enzyme
  • GPH1 YPR160W Glycogen PHosphorylase
  • GDB1,
  • GLG1,
  • GLG2,
  • GSY1,
  • GSY2,
  • FPS1

Tryptophan degradation/ de novo NAD biosynthesis

  • BNA1 YJR025c tryptophan met 3-hydroxyanthranilate 3,4-dioxygenase activity
  • BNA2 YJR078W tryptophan 2,3-dioxygenase activity
  • BNA4 YBL098W tryptophan met kynurenine 3-monooxygenase
  • BNA5 YLR231C tryptophan met kynureninase
  • BNA6 YFR047C biosynthesis of NAD from tryptophan via kynurenine

peroxisomal proteins and components of the fatty acid oxidation pathway

  • PEX8
  • PEX21
  • PXA2
  • FOX1
  • FOX3
  • SPS19
  • DCI1
  • ECI1
  • FAA2
  • TES1
  • CAT2
  • EEB1 YPL095c medium-chain fatty acid ethyl ester biosynthesis during fermentation
  • EHT1 YBR177c medium-chain fatty acid metabolic process
  • YMR210w medium-chain fatty acid metabolic process

Autophagy

  • YHR195W NVJ1
  • YDR357C CNL1
  • ATG10,16,18,21,23,27

biotin synthesis enzymes

  • BIO4
  • BIO3
  • + one?

TMA

  • TMA7,10,16,17,20,24,64,108

May be conserved but not yet detected

  • YDl156W (WD repeat)
  • YML129C COX14
  • YGR008C
  • YJL131C AIM23? mitochondrial IF3
  • tom6 (small)
  • RSF1 YMR030W (yeast only)
  • YCL044C
  • DLS1
  • IPT1
  • cox23 yhr116w
  • OGG1
  • HPA2
  • YPL123C
  • YDL002
  • YBR152W
  • YBL031W
  • YJR101c-A
  • YGL217W
  • PRP7
  • PRP6
  • NTC20 YBR188C
  • UTP8 YGR128C
  • UTP9 YHR196W
  • TOM5 family will be In Pfam release 23
  • TOM6 family will be In Pfam release 23
  • SPC12 PF06645
  • YLR119W
  • there are also 64 essential genes in budding yeast which do not appear to

have a fission yeast ortholog

Distant orthologs not picked up by most ortholog predictors