Version 10 (modified by 6 years ago) (diff) | ,
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Rough guidelines for when to pre- or post-compose phenotype terms with condition information
Most phenotypes are defined independently of any experimental conditions, since we can annotate conditions separately. There are a few exceptions, however, in which condition information is included as one of the features of a pre-composed term, usually for things that users will want to find easily, e.g. "temperature sensitive".
- Always pre-compose:
- any sensitive to chemical other than N or C source
- any resistant to chemical other than N or C source
- Always post-compose (i.e. capture conditions at annotation time, not as part of a complicated phenotype term)
- anything other than viable/inviable (or growth/no growth/death) at high temperature
- anything other than viable/inviable (or growth/no growth/death) at low temperature
- presence or absence of chemicals with phenotypes other than population growth sensitivity/resistance
- Grey areas - phenotypes curators haven't felt sure about, but are leaving in place until/unless problems crop up [updated 2013-01-07, 2013-09-06]
- viable/inviable (or growth/no growth/death) on specific carbon source
- anything during starvation for a specific nutrient/limiting [stuff]
- growth at [whatever] pH, e.g. FYPO:0001157 increased cell growth rate at high pH
- viable/inviable or population growth at high or low temperature (aka sensitive/resistant to heat/cold)
- discussing whether to make a pre/post distinction along cell vs. population lines
- Other outstanding issues
- in vitro enzyme assays, with inhibitors (e.g. SF #238)
- no terms included yet (last updated 2013-01-07)
- in vitro enzyme assays, with inhibitors (e.g. SF #238)
- Other decisions (archived)
- As of 2013-11-04, decided to use conditions for aerobic/semi-aerobic/anaerobic where FYPO term mentions carbon source.
updated 2012-06-15, 2013-01-07, 2013-09-06, 2013-11-04, 2015-04-10 mah